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Publications from this research unit
This page shows only publications with IRC as the affiliation of at least one author.
Publications by IRC members mentioning other affiliations are not in our database. Sorry.
See "Extra muros" papers of the units.
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Ackaert, C, Smiejkowska, N, Xavier, C, Sterckx, YGJ, Denies, S, Stijlemans, B, Elkrim, Y, Devoogdt, N, Caveliers, V, Lahoutte, T, Muyldermans, S, Breckpot, K, Keyaerts, M. Immunogenicity Risk Profile of Nanobodies Front Immunol 12, 632687, 2021. (Epub 2021 Mar 9) 
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Ackermann, M, Anders, HJ, Bilyy, R, Bowlin, GL, Daniel, C, De Lorenzo, R, Egeblad, M, Henneck, T, Hidalgo, A, Hoffmann, M, Hohberger, B, Kanthi, Y, Kaplan, MJ, Knight, JS, Knopf, J, Kolaczkowska, E, Kubes, P, Leppkes, M, Mahajan, A, et al.. Patients with COVID-19: in the dark-NETs of neutrophils Cell Death Differ , in press, 2021. (Epub 2021 May 24)
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Adami, V, Homer, N, Utz, N, Lippens, S, Rappoport, JZ, Fernandez-Rodriguez, J. An international survey of Training Needs and Career Paths of Core Facility Staff J Biomol Tech 32, 1-9, 2021. (Epub 2020 Nov 20)
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Aegerter, H, Smole, U, Heyndrickx, I, Verstraete, K, Savvides, SN, Hammad, H, Lambrecht, BN. Charcot-Leyden crystals and other protein crystals driving type 2 immunity and allergy Curr Opin Immunol 72, 72-78, 2021. (Epub 2021 Apr 16)
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Afonina, IS, Van Nuffel, E, Beyaert, R. Immune responses and therapeutic options in psoriasis Cell Mol Life Sci 78, 2709–2727, 2021. (Epub 2021 Jan 2)
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Aguilera-Lizarraga, J, Florens, MV, Viola, MF, Jain, P, Decraecker, L, Appeltans, I, Cuende-Estevez, M, Fabre, N, Van Beek, K, Perna, E, Balemans, D, Stakenborg, N, Theofanous, S, Bosmans, G, Mondelaers, SU, Matteoli, G, Ibiza Martinez, S, Lopez-Lopez, C, Jaramillo-Polanco, J, et al.. Local immune response to food antigens drives meal-induced abdominal pain Nature 590, 151-156, 2021. (Epub 2021 Jan 13)
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Almeida, L, Dhillon-LaBrooy, A, Castro, CN, Adossa, N, Carriche, GM, Guderian, M, Lippens, S, Dennerlein, S, Hesse, C, Lambrecht, BN, Berod, L, Schauser, L, Blazar, BR, Kalesse, M, Muller, R, Moita, LF, Sparwasser, T. Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis Immunity 54, 68-83, 2021. (Epub 2020 Nov 24)
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Anderson, CJ, Medina, CB, Barron, BJ, Karvelyte, L, Aaes, TL, Lambertz, I, Perry, JSA, Mehrotra, P, Goncalves, A, Lemeire, K, Blancke, G, Andries, V, Ghazavi, F, Martens, A, van Loo, G, Vereecke, L, Vandenabeele, P, Ravichandran, KS. Microbes exploit death-induced nutrient release by gut epithelial cells Nature 596, 262-267, 2021. (Epub 2021 Aug 4)
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Andries, L, Masin, L, Navarro, MS, Zaunz, S, Claes, M, Bergmans, S, Brouwers, V, Lefevere, E, Verfaillie, C, Movahedi, K, De Groef, L, Moons, L. MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System Cells 10, 1672, 2021. (Epub 2021 Jul 2)
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Arandjelovic, S, Perry, JSA, Zhou, M, Ceroi, A, Smirnov, I, Walk, SF, Shankman, LS, Cambre, I, Onengut-Gumuscu, S, Elewaut, D, Conrads, TP, Ravichandran, KS. ELMO1 signaling is a promoter of osteoclast function and bone loss Nat Commun 12, 4974, 2021. (Epub 2021 Aug 17)
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Backers, L, Parton, B, De Bruyne, M, Tavernier, SJ, Van Den Bogaert, K, Lambrecht, BN, Haerynck, F, Claes, KBM. Missing heritability in Bloom syndrome: First report of a deep intronic variant leading to pseudo-exon activation in the BLM gene Clin Genet 99, 292-297, 2021. (Epub 2020 Oct 9)
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Baeten, P, Van Zeebroeck, L, Kleinewietfeld, M, Hellings, N, Broux, B. Improving the Efficacy of Regulatory T Cell Therapy Clin Rev Allergy Immunol , in press, 2021. (Epub 2021 Jul 5)
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Baptista, AP, Gerner, MY. Lymphoid stromal cells proGrem dendritic cell homeostasis Nat Immunol 22, 541-543, 2021. (Epub 2021 Apr 26)
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Baraliakos, X, Van den Bosch, F, Machado, PM, Gensler, LS, Marzo-Ortega, H, Sherif, B, Quebe-Fehling, E, Porter, B, Gaillez, C, Deodhar, A. Achievement of Remission Endpoints with Secukinumab Over 3 Years in Active Ankylosing Spondylitis: Pooled Analysis of Two Phase 3 Studies Rheumatol Ther 8, 273-288, 2021. (Epub 2020 Dec 22)
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Baudhuin, H, Cousaert, J, Vanwolleghem, P, Raes, G, Caveliers, V, Keyaerts, M, Lahoutte, T, Xavier, C. (68)Ga-Labeling: Laying the Foundation for an Anti-Radiolytic Formulation for NOTA-sdAb PET Tracers Pharmaceuticals (Basel) 14, 448, 2021. (Epub 2021 May 10)
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Baudhuin, H, Puttemans, J, Hanssens, H, Vanwolleghem, P, Hernot, S, Raes, G, Xavier, C, Lahoutte, T, Debie, P. Decorating sdAbs with Chelators: Effect of Conjugation on Biodistribution and Functionality Pharmaceuticals (Basel) 14, 407, 2021. (Epub 2021 Apr 25)
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Baudhuin, H, Van Bockstal, PJ, De Beer, T, Vaneycken, I, Bridoux, J, Raes, G, Caveliers, V, Keyaerts, M, Devoogdt, N, Lahoutte, T, Xavier, C. Lyophilization of NOTA-sdAbs: first step towards a cold diagnostic kit for (68)Ga-labeling Eur J Pharm Biopharm , in press, 2021. (Epub 2021 Jun 26)
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Bolli, E, Scherger, M, Arnouk, SM, Pombo Antunes, AR, Strassburger, D, Urschbach, M, Stickdorn, J, De Vlaminck, K, Movahedi, K, Rader, HJ, Hernot, S, Besenius, P, Van Ginderachter, JA, Nuhn, L. Targeted Repolarization of Tumor-Associated Macrophages via Imidazoquinoline-Linked Nanobodies Adv Sci (Weinh) 8, 2004574, 2021. (Epub 2021 Mar 8)
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Borras-Tuduri, R, Alcaide, A, Aspeslag, S, Usero, L, Serra, C, Roura-Mir, C, Elewaut, D, Llebaria, A. New paradigm in NKT cell antigens: MCS-0208 (2-(Hydroxymethyl)phenylthio-phytoceramide) an aryl-phytoceramide compound with a single hydroxyl group stimulates NKT cells ChemMedChem 16, in press, 2021. (Epub 2021 Apr 6)
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Bosteels, C, Fierens, K, De Prijck, S, Van Moorleghem, J, Vanheerswynghels, M, De Wolf, C, Chalon, A, Collignon, C, Hammad, H, Didierlaurent, AM, Lambrecht, BN. CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Immunity by the Human Vaccine Adjuvant System AS01 Front Immunol 11, 606805, 2021. (Epub 2021 Jan 14)
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Braun, J, Blanco, R, Marzo-Ortega, H, Gensler, LS, van den Bosch, F, Hall, S, Kameda, H, Poddubnyy, D, van de Sande, M, Wiksten, AS, Porter, BO, Shete, A, Richards, HB, Haemmerle, S, Deodhar, A. Secukinumab in non-radiographic axial spondyloarthritis: subgroup analysis based on key baseline characteristics from a randomized phase III study, PREVENT Arthritis Res Ther 23, 231, 2021. (Epub 2021 Sep 4)
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Brightling, C, Kulkarni, S, Lambrecht, BN, Sandham, D, Weiss, M, Altman, P. The pharmacology of the prostaglandin D2 receptor 2 (DP2) receptor antagonist, fevipiprant Pulm Pharmacol Ther 68, 102030, 2021. (Epub 2021 Apr 4)
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Burgelman, M, Vandendriessche, C, Vandenbroucke, RE. Extracellular Vesicles: A Double-Edged Sword in Sepsis Pharmaceuticals (Basel) 14, 829, 2021. (Epub 2021 Aug 23)
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Cannoodt, R, Saelens, W, Deconinck, L, Saeys, Y. Spearheading future omics analyses using dyngen, a multi-modal simulator of single cells Nat Commun 12, 3942, 2021. (Epub 2021 Jun 24)
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Carbo, JM, Leon, TE, Font-Diaz, J, De la Rosa, JV, Castrillo, A, Picard, FR, Staudenraus, D, Huber, M, Cedo, L, Escola-Gil, JC, Campos, L, Bakiri, L, Wagner, EF, Caelles, C, Stratmann, T, Van Ginderachter, JA, Valledor, AF. Pharmacological activation of LXR alters the expression profile of tumor-associated macrophages and the abundance of regulatory T cells in the tumor microenvironment Cancer Res 81, 968-985, 2021. (Epub 2020 Dec 23)
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Cloots, E, Debeuf, N, Deswarte, K, Fayazpour, F, Vanheerswynghels, M, De Wolf, C, Van De Velde, E, Hammad, H, Lambrecht, BN, Eyckerman, S, Janssens, S. IRE1beta does not affect mucus secretion during allergic asthma development in a house dust mite murine model Allergy , in press, 2021. (Epub 2021 Aug 12)
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Cloots, E, Simpson, MS, De Nolf, C, Lencer, WI, Janssens, S, Grey, MJ. Evolution and function of the epithelial cell-specific ER stress sensor IRE1beta Mucosal Immunol , in press, 2021. (Epub 2021 Jun 1)
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Coornaert, I, Puylaert, P, Marcasolli, G, Grootaert, MOJ, Vandenabeele, P, De Meyer, GRY, Martinet, W. Impact of myeloid RIPK1 gene deletion on atherogenesis in ApoE-deficient mice Atherosclerosis 322, 51-60, 2021. (Epub 2021 Feb 24)
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de Haan, W, Dheedene, W, Apelt, K, Decombas-Deschamps, S, Vinckier, S, Verhulst, S, Conidi, A, Deffieux, T, Staring, MW, Vandervoort, P, Caluwe, E, Lox, M, Mannaerts, I, Takagi, T, Jaekers, J, Berx, G, Haigh, J, Topal, B, Zwijsen, A, et al.. Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis Cardiovasc Res , in press, 2021. (Epub 2021 Apr 28)
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Delaney, C, Farrell, M, Doherty, CP, Brennan, K, O'Keeffe, E, Greene, C, Byrne, K, Kelly, E, Birmingham, N, Hickey, P, Cronin, S, Savvides, SN, Doyle, SL, Campbell, M. Attenuated CSF-1R signalling drives cerebrovascular pathology EMBO Mol Med 13, e12889, 2021. (Epub 2020 Dec 22)
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Delanghe, T, Huyghe, J, Lee, S, Priem, D, Van Coillie, S, Gilbert, B, Choi, SM, Vandenabeele, P, Degterev, A, Cuny, GD, Dondelinger, Y, Bertrand, MJM. Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor Cell Death Dis 12, 699, 2021. (Epub 2021 Jul 14)
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De Mits, S, De Craemer, AS, Deroo, L, Renson, T, Van den Bosch, FE, Carron, P, Elewaut, D. Unexpected impact of COVID-19 lockdown on spinal mobility and health perception in spondyloarthritis Ann Rheum Dis , in press, 2021. (Epub 2021 Jun 29)
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Deodhar, A, van der Heijde, D, Sieper, J, Van den Bosch, F, Maksymowych, WP, Kim, TH, Kishimoto, M, Ostor, A, Combe, B, Sui, Y, Chu, AD, Song, IH. Upadacitinib in Active Ankylosing Spondylitis: 1-Year Results From the Double-Blind, Placebo-Controlled SELECT-AXIS 1 Study and Open-Label Extension Arthritis Rheumatol , in press, 2021. (Epub 2021 Jul 1)
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de Reuver, R, Dierick, E, Wiernicki, B, Staes, K, Seys, L, De Meester, E, Muyldermans, T, Botzki, A, Lambrecht, BN, Van Nieuwerburgh, F, Vandenabeele, P, Maelfait, J. ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation Cell Rep 36, 109500, 2021. (Epub 2021 Aug 10)
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De Schutter, E, Cappe, B, Wiernicki, B, Vandenabeele, P, Riquet, FB. Plasma membrane permeabilization following cell death: many ways to dye! Cell Death Discov 7, 183, 2021. (Epub 2021 Jul 19)
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De Schutter, E, Roelandt, R, Riquet, FB, Van Camp, G, Wullaert, A, Vandenabeele, P. Punching Holes in Cellular Membranes: Biology and Evolution of Gasdermins Trends Cell Biol 31, 500-513, 2021. (Epub 2021 Mar 23)
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Desmet, S, Saeys, Y, Verstaen, K, Dauwe, R, Kim, H, Niculaes, C, Fukushima, A, Goeminne, G, Vanholme, R, Ralph, J, Boerjan, W, Morreel, K. Maize specialized metabolome networks reveal organ-preferential mixed glycosides Comput Struct Biotechnol J 19, 1127-1144, 2021. (Epub 2021 jan 26)
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De Spiegeleer, A, Kahya, H, Sanchez-Rodriguez, D, Piotrowicz, K, Surquin, M, Marco, E, Detremerie, C, Hussein, D, Hope, S, Dallmeier, D, Decker, G, Hrnciarikova, D, Czesak, J, Toscano-Rico, M, Meza-Valderrama, D, Bahat, G, Descamps, A, Wynendaele, E, Elewaut, D, et al.. Acute sarcopenia changes following hospitalization: influence of pre-admission care dependency level Age Ageing , in press, 2021. (Epub 2021 Aug 9)
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De Spiegeleer, A, Van Migerode, J, Bronselaer, A, Wynendaele, E, Peelman, M, Vandaele, F, Byttebier, G, De Tre, G, Belmans, L, Van De Wiele, C, Sathekge, M, Van Dijck, D, Saxberg, B, Alexander, M, Fedson, D, Elewaut, D, Van Den Noortgate, N, De Spiegeleer, B. Statin Intake and All-Cause Mortality among Older Nursing Home Residents Gerontology , in press, 2021. (Epub 2021 Jun 16)
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de Vlam, K, Steinfeld, S, Toukap, AN, van den Bosch, F, Joos, R, Geussens, P, Leroi, H, Lories, R, Investigators, BS. The burden of psoriatic arthritis in the biological era: data from the Belgian Epidemiological Psoriatic Arthritis Study (BEPAS) Rheumatology (Oxford) , in press, 2021. (Epub 2021 Mar 12)
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De Vrieze, J, Baptista, AP, Nuhn, L, Van Herck, S, Deswarte, K, Yu, HJ, Lambrecht, BN, De Geest, BG. Lipid Nature and Alkyl Length Influence Lymph Node Accumulation of Lipid-Polyethylene Glycol Amphiphiles Advanced Therapeutics , in press, 2021. (Epub 2021 Jul 26)
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Dhont, S, Derom, E, Van Braeckel, E, Depuydt, P, Lambrecht, BN. Conceptions of the pathophysiology of happy hypoxemia in COVID-19 Respir Res 22, 12, 2021. (Epub 2021 Jan 8)
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Duetz, C, Van Gassen, S, Westers, TM, van Spronsen, MF, Bachas, C, Saeys, Y, van de Loosdrecht, AA. Computational flow cytometry as a diagnostic tool in suspected-myelodysplastic syndromes Cytometry A , in press, 2021. (Epub 2021 May 3)
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Elewaut, D, Braun, J, Anderson, JK, Arikan, D, Chen, S, Hojnik, M, De Craemer, AS, Curtis, JR. Low Incidence of Inflammatory Bowel Disease Adverse Events in Adalimumab Clinical Trials Across Nine Different Diseases Arthritis Care Res (Hoboken) 73, 289–295, 2021. (Epub 2020 Feb 26)
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Fleischmann, RM, Blanco, R, Hall, S, Thomson, GTD, Van den Bosch, FE, Zerbini, C, Bessette, L, Enejosa, J, Li, Y, Song, Y, DeMasi, R, Song, IH. Switching between Janus kinase inhibitor upadacitinib and adalimumab following insufficient response: efficacy and safety in patients with rheumatoid arthritis Ann Rheum Dis 80, 432-439, 2021. (Epub 2020 Nov 4)
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Geisberger, S, Bartolomaeus, H, Neubert, P, Willebrand, R, Zasada, C, Bartolomaeus, T, McParland, V, Swinnen, D, Geuzens, A, Maifeld, A, Krampert, L, Vogl, M, Mahler, A, Wilck, N, Marko, L, Tilic, E, Forslund, SK, Binger, KJ, Stegbauer, J, et al.. Salt Transiently Inhibits Mitochondrial Energetics in Mononuclear Phagocytes Circulation 144, 144-158, 2021. (Epub 2021 Apr 28)
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Germanova, D, Keirsse, J, Kohler, A, Hastir, JF, Demetter, P, Delbauve, S, Elkrim, Y, Verset, L, Larbanoix, L, Preyat, N, Laurent, S, Nedospasov, S, Donckier, V, Van Ginderachter, JA, Flamand, V. Myeloid TNF and HO-1 regulate the progression of colorectal liver metastases during hepatic ischemia-reperfusion Int J Cancer 148, 1276–1288, 2021. (Epub 2020 Oct 10)
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Gola, A, Dorrington, MG, Speranza, E, Sala, C, Shih, RM, Radtke, AJ, Wong, HS, Baptista, AP, Hernandez, JM, Castellani, G, Fraser, IDC, Germain, RN. Commensal-driven immune zonation of the liver promotes host defence Nature 589, 131-136, 2021. (Epub 2020 Nov 25)
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Gorle, N, Bauwens, E, Haesebrouck, F, Smet, A, Vandenbroucke, RE. Helicobacter and the Potential Role in Neurological Disorders: There Is More Than Helicobacter pylori Front Immunol 11, 584165, 2021. (Epub 2021 Jan 28)
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Grigoryan, R, Costas-Rodriguez, M, Van Wonterghem, E, Vandenbroucke, RE, Vanhaecke, F. Effect of Endotoxemia Induced by Intraperitoneal Injection of Lipopolysaccharide on the Mg isotopic Composition of Biofluids and Tissues in Mice Front Med (Lausanne) 8, 664666, 2021. (Epub 2021 Jul 23)
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