» Home » Research 
Print this pageEmail this page URLConvert this page to PDF

Publications from this research unit

This page shows only publications with IRC as the affiliation of at least one author.
Publications by IRC members mentioning other affiliations are not in our database. Sorry.
See "Extra muros" papers of the units.

For copyright reasons, PDF-versions of our publications are available on the intranet only (login required  ). If you would like to receive a reprint of an IRC paper, please copy/paste the reference in the
reprint request form 


Cambre, I, Gaublomme, D, Schryvers, N, Lambrecht, S, Lories, R, Venken, K, Elewaut, D.
Running promotes chronicity of arthritis by local modulation of complement activators and impairing T regulatory feedback loops
Ann Rheum Dis , in press, 2019. (Epub 2019 Mar 30)

Chuang, YT, Leung, K, Chang, YJ, DeKruyff, RH, Savag, PB, Cruse, R, Benoit, C, Elewaut, D, Baumgarth, N, Umetsu, DT.
A Natural Killer T cell subset that protects against airway hyperreactivity
J Allergy Clin Immunol 143, 565-576, 2019. (Epub 2018 May 28)

Claudepierre, P, Van den Bosch, F, Sarzi-Puttini, P, Vastesaeger, N, Govoni, M, Kachroo, S.
Treatment with golimumab or infliximab reduces health resource utilization and increases work productivity in patients with ankylosing spondylitis in the QUO-VADIS study, a large, prospective real-life cohort
Int J Rheum Dis , in press, 2019. (Epub 2019 Apr 15)

Gracey, E, Dumas, E, Yerushalmi, M, Qaiyum, Z, Inman, RD, Elewaut, D.
The ties that bind: skin, gut and spondyloarthritis
Curr Opin Rheumatol 31, 62-69, 2019. (Epub 2018 Nov 6)

Janssens, J, Bitra, A, Wang, J, Decruy, T, Venken, K, van der Eycken, J, Elewaut, D, Zajonc, DM, van Calenbergh, S.
4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies
ChemMedChem 14, 147-168, 2019. (Epub 2018 Dec 17)

Petta, I, Peene, I, Elewaut, D, Vereecke, L, De Bosscher, K.
Risks and benefits of corticosteroids in arthritic diseases in the clinic
Biochem Pharmacol , in press, 2019. (Epub 2019 Apr 10)

Van Hove, H, Martens, L, Scheyltjens, I, De Vlaminck, K, Pombo Antunes, AR, De Prijck, S, Vandamme, N, De Schepper, S, Van Isterdael, G, Scott, CL, Aerts, J, Berx, G, Boeckxstaens, GE, Vandenbroucke, RE, Vereecke, L, Moechars, D, Guilliams, M, Van Ginderachter, JA, Saeys, Y, Movahedi, K.
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
Nat Neurosci , in press, 2019. (Epub 2019 May 6)

Veale, DJ, McGonagle, D, McInnes, IB, Krueger, JG, Ritchlin, CT, Elewaut, D, Kanik, KS, Hendrikx, T, Berstein, G, Hodge, J, Telliez, JB.
The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis
Rheumatology (Oxford) 58, 197-205, 2019. (Epub 2018 Apr 3)

Venken, K, Jacques, P, Mortier, C, Labadia, ME, Decruy, T, Coudenys, J, et al., Van Gassen, S, Martens, L, Smith, D, Harcken, C, Wahle, J, Wang, CT, Verheugen, E, Schryvers, N, Varkas, G, Cypers, H, et al.,Van den Bosch, F, Saeys, Y, Nabozny, G, Elewaut D.
RORgammat inhibition selectively targets IL-17 producing iNKT and gammadelta-T cells enriched in Spondyloarthritis patients
Nat Commun 10, 9, 2019. (Epub 2019 Jan 2)

Bogie, JF, Boelen, E, Louagie, E, Delputte, P, Elewaut, D, van Horssen, J, Hendriks, JJ, Hellings, N.
CD169 is a marker for highly pathogenic phagocytes in multiple sclerosis
Multiple Sclerosis Journal 24, 290-300, 2018. (Epub 2017 Mar 1)

Burmester, GR, Kremer, JM, Van den Bosch, F, Kivitz, A, Bessette, L, Li, Y, Zhou, Y, Othman, AA, Pangan, AL, Camp, HS.
Safety and efficacy of upadacitinib in patients with rheumatoid arthritis and inadequate response to conventional synthetic disease-modifying anti-rheumatic drugs (SELECT-NEXT): a randomised, double-blind, placebo-controlled phase 3 trial
Lancet 391, 2503-2512, 2018. (Epub 2018 Jun 23)

Cambre, I, Gaublomme, D, Burssens, A, Jacques, P, Schryvers, N, De Muynck, A, Meuris, L, Lambrecht, S, Carter, S, de Bleser, P, Saeys, Y, Van Hoorebeke, L, Kollias, G, Mack, M, Simoens, P, Lories, R, Callewaert, N, Schett, G, Elewaut, D.
Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis
Nat Commun 9, 4613, 2018. (Epub 2018 Nov 5)

Carron, P, Varkas, G, Renson, T, Colman, R, Elewaut, D, Van den Bosch, F.
High rate of drug-free remission after induction therapy with golimumab in early peripheral spondyloarthritis
Arthritis Rheumatol 70, 1769-1777, 2018. (Epub 2018 May 27)

De Bruyne, M, Bogaert, DJ, Venken, K, Van den Bossche, L, Bonroy, C, Roels, L, Tavernier, SJ, van de Vijver, E, Driessen, A, van Gijn, M, Gamez-Diaz, L, Elewaut, D, Grimbacher, B, Haerynck, F, Moes, N, Dullaers, M.
A novel LRBA mutation presents with normal CTLA-4 and overactive Th17 immunity
J Allergy Clin Immunol , in press, 2018. (Epub 2018 Sep 4)

Gilis, E, Mortier, C, Venken, K, Debusschere, K, Vereecke, L, Elewaut, D.
The Role of the Microbiome in Gut and Joint Inflammation in Psoriatic Arthritis and Spondyloarthritis
J Rheumatol Suppl 94, 36-39, 2018. (Epub 2018 Jun)

Govindarajan, S, Gaublomme, D, Van der Cruyssen, R, Verheugen, E, Van Gassen, S, Saeys, Y, Tavernier, S, Iwawaki, T, Bloch, Y, Savvides, SN, Lambrecht, BN, Janssens, S, Elewaut, D, Drennan, MB.
Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha
Nat Commun 9, 5340, 2018. (Epub 2018 Dec 17)

Jans, L, De Kock, I, Herregods, N, Verstraete, KL, Van den Bosch, FE, Carron, P, Oei, EH, Elewaut, D, Jacques, P.
Response to: 'The use of dual-energy CT to detect and depict bone marrow oedema in rheumatoid arthritis: is it ready to substitute MRI?' by Wu et al
Ann Rheum Dis , annrheumdis-2018-213960, 2018. (Epub 2018 Jul 12)

Jans, L, De Kock, I, Herregods, N, Verstraete, K, Van den Bosch, F, Carron, P, Oei, EH, Elewaut, D, Jacques, P.
Dual-energy CT: a new imaging modality for bone marrow oedema in rheumatoid arthritis
Ann Rheum Dis , in press, 2018. (Epub 2018 Mar 1)

Kiltz, U, van der Heijde, D, Boonen, A, Akkoc, N, Bautista-Molano, W, Burgos-Vargas, R, Wei, JC, Chiowchanwisawakit, P, Dougados, M, Duruoz, MT, Elzorkany, BK, Gaydukova, I, Gensler, LS, Gilio, M, Grazio, S, et al., Van den Bosch, FE, et al.
Measurement properties of the ASAS Health Index: results of a global study in patients with axial and peripheral spondyloarthritis
Ann Rheum Dis 77, 1311-1317, 2018. (Epub 2018 Sep)

Kloppenburg, M, Ramonda, R, Bobacz, K, Kwok, WY, Elewaut, D, Huizinga, TWJ, Kroon, FPB, Punzi, L, Smolen, JS, Vander Cruyssen, B, Wolterbeek, R, Verbruggen, G, Wittoek, R.
Etanercept in patients with inflammatory hand osteoarthritis (EHOA): a multicentre, randomised, double-blind, placebo-controlled trial
Ann Rheum Dis 77, 1757-1764, 2018. (Epub 2018 Oct 3)

Laloo, F, Herregods, N, Jaremko, JL, Carron, P, Elewaut, D, Van den Bosch, F, Verstraete, K, Jans, L.
New bone formation in the intervertebral joint space in spondyloarthritis: An MRI study
Eur J Radiol 109, 210-217, 2018. (Epub 2018 Dec)

Mease, P, Coates, LC, Helliwell, PS, Stanislavchuk, M, Rychlewska-Hanczewska, A, Dudek, A, Abi-Saab, W, Tasset, C, Meuleners, L, Harrison, P, Besuyen, R, Van der Aa, A, Mozaffarian, N, Greer, JM, Kunder, R, Van den Bosch, F, Gladman, DD.
Efficacy and safety of filgotinib, a selective Janus kinase 1 inhibitor, in patients with active psoriatic arthritis (EQUATOR): results from a randomised, placebo-controlled, phase 2 trial
Lancet 392, 2367-2377, 2018. (Epub 2018 Dec 1)

Mortier, C, Govindarajan, S, Venken, K, Elewaut, D.
It Takes "Guts" to Cause Joint Inflammation: Role of Innate-Like T Cells
Front Immunol 9, in press, 2018. (Epub 2018 Jun 29)

Nikiphorou, E, Ramiro, S, van der Heijde, D, Norton, S, Molto, A, Dougados, M, van den Bosch, F, Landewe, R, Force, A-CT.
Comorbidities in Spondyloarthritis associate with poor function, work disability and quality of life: Results from the ASAS-COMOSPA study
Arthritis Care Res (Hoboken) , in press, 2018. (Epub 2017 Nov 10)

Nikiphorou, E, van der Heijde, D, Norton, S, Landewe, RB, Molto, A, Dougados, M, Van den Bosch, FE, Ramiro, S, Collaborators.
Inequity in biological DMARD prescription for spondyloarthritis across the globe: results from the ASAS-COMOSPA study
Ann Rheum Dis 77, 3, 2018. (Epub 2017 Dec 8)

Rodrigues Manica, S, Sepriano, A, Ramiro, S, Pimentel Santos, F, Putrik, P, Nikiphorou, E, Norton, S, Molto, A, Dougados, M, van der Heijde, D, Landewe, RBM, van den Bosch, FE, Boonen, A.
Work participation in spondyloarthritis across countries: analysis from the ASAS-COMOSPA study
Ann Rheum Dis 77, 1303-1310, 2018. (Epub 2018 Sep)

Van den Bosch, F, Coates, L.
Clinical management of psoriatic arthritis
Lancet 391, 2285-2294, 2018. (Epub 2018 Jun 2)

Van den Bosch, F, Flipo, RM, Braun, J, Vastesaeger, N, Kachroo, S, Govoni, M.
Clinical and quality of life improvements with golimumab or infliximab in a real-life ankylosing spondylitis population: the QUO-VADIS study
Clin Exp Rheumatol 37, 199-207, 2018. (Epub 2018 Jul 19)

Varkas, G, de Hooge, M, Renson, T, De Mits, S, Carron, P, Jacques, P, Moris, M, Souverijns, G, Jans, L, Elewaut, D, Van den Bosch, F.
Effect of mechanical stress on magnetic resonance imaging of the sacroiliac joints: assessment of military recruits by magnetic resonance imaging study
Rheumatology (Oxford) 57, 508-513, 2018. (Epub 2017 Dec 14)

Varkas, G, Elewaut, D.
Response to: 'Simultaneous inhibition of alpha4/beta7 integrin and tumor necrosis factor-alpha in concomitant spondyloarthritis and inflammatory bowel disease' by Richard et al
Ann Rheum Dis , in press, 2018. (Epub 2018 Jan 26)

Varkas, G, Vastesaeger, N, Cypers, H, Colman, R, Renson, T, Van Praet, L, Carron, P, Raeman, F, Devinck, M, Gyselbrecht, L, Corluy, L, Piette, Y, Lenaerts, J, Thevissen, K, Vanneuville, B, Van den Bosch, F, Elewaut, D.
Association of Inflammatory Bowel Disease and Acute Anterior Uveitis, but Not Psoriasis, With Disease Duration in Patients With Axial Spondyloarthritis: Results From Two Belgian Nationwide Axial Spondyloarthritis Cohorts
Arthritis Rheumatol 70, 1588-1596, 2018. (Epub 2018 May 9)

Venken, K, Favreau, M, Gaublomme, D, Menu, E, Vanderkerken, K, Elewaut, D.
Checkpoint inhibition in the treatment of multiple myeloma: A way to boost innate-like T cell anti-tumor function?
Mol Immunol 101, 521-526, 2018. (Epub 2018 Aug 15)

Vereecke, L, Elewaut, D.
Tumour necrosis factor: out of my heart!
Ann Rheum Dis 77, 793-794, 2018. (Epub 2018 Apr 3)

Wang, X, Shaalan, A, Liefers, S, Coudenys, J, Elewaut, D, Proctor, GB, Bootsma, H, Kroese, FGM, Pringle, S.
Dysregulation of NF-kB in glandular epithelial cells results in Sjogren's-like features
PLoS One 13, e0200212, 2018. (Epub 2018 Aug 1)

Wittoek, R, Carron, P, Lambert, B, Meersseman, P, Verbruggen, G, Van den Bosch, F, Elewaut, D.
Immunoscintigraphic detection of tumour necrosis factor by radiolabelled certolizumab pegol in patients with erosive hand osteoarthritis: a proof-of-concept study
Ann Rheum Dis 77, 310-311, 2018. (Epub 2016 Dec 8)

Zhao, M, Svensson, MND, Venken, K, Chawla, A, Liang, S, Engel, I, Mydel, P, Day, J, Elewaut, D, Bottini, N, Kronenberg, M.
Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70
Nat Commun 9, 2627, 2018. (Epub 2018 Jul 6)

Bakker, P, Molto, A, Etcheto, A, Van den Bosch, F, Landewe, R, van Gaalen, F, Dougados, M, van der Heijde, D.
The performance of different classification criteria sets for spondyloarthritis in the worldwide ASAS-COMOSPA study
Arthritis Res Ther 19, 96, 2017. (Epub 2017 May 16)

Bloch, Y, Bouchareychas, L, Merceron, R, Skladanowska, K, Van den Bossche, L, Detry, S, Govindarajan, S, Elewaut, D, Haerynck, F, Dullaers, M, Adamopoulos, IE, Savvides, SN.
Structural Activation of Pro-inflammatory Human Cytokine IL-23 by Cognate IL-23 Receptor Enables Recruitment of the Shared Receptor IL-12Rbeta1
Immunity 48, 45-58, 2017. (Epub 2017 Dec 21)

Carron, P, Varkas, G, Cypers, H, Van Praet, L, Elewaut, D, Van den Bosch, F, group, Ci.
Anti-TNF-induced remission in very early peripheral spondyloarthritis: the CRESPA study
Ann Rheum Dis 76, 1389-1395, 2017. (Epub 2017 Feb 17)

Ciccia, F, Guggino, G, Rizzo, A, Alessandro, R, Luchetti, MM, Milling, S, Saieva, L, Cypers, H, Stampone, T, Di Benedetto, P, Gabrielli, A, Fasano, A, Elewaut, D, Triolo, G.
Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis
Ann Rheum Dis 76, 1123-1132, 2017. (Epub 2017 Jan 9)

De Beule, N, Menu, E, Bertrand, MJ, Favreau, M, De Bruyne, E, Maes, K, De Veirman, K, Radwanska, M, Samali, A, Magez, S, Vanderkerken, K, De Trez, C.
Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cells
Oncotarget 8, 52016-52025, 2017. (Epub 2017 May 24)

Debusschere, K, Cambre, I, Gracey, E, Elewaut, D.
Born to run: The paradox of biomechanical force in spondyloarthritis from an evolutionary perspective
Best Pract Res Clin Rheumatol 31, 887-894, 2017. (Epub 2017 Dec)

De Schryver, M, Cappoen, D, Elewaut, D, Nauwynck, HJ, Maes, L, Caljon, G, Cos, P, Delputte, PL.
Monoclonal antibody binding to the macrophage-specific receptor sialoadhesin alters the phagocytic properties of human and mouse macrophages
Cell Immunol 312, 51-60, 2017. (Epub 2016 Dec 9)

De Wilde, K, Martens, A, Lambrecht, S, Jacques, P, Drennan, MB, Debusschere, K, Govindarajan, S, Coudenys, J, Verheugen, E, Windels, F, Catrysse, L, Lories, R, McGonagle, D, Beyaert, R, van Loo, G, Elewaut, D.
A20 inhibition of STAT1 expression in myeloid cells: a novel endogenous regulatory mechanism preventing development of enthesitis
Ann Rheum Dis 76, 585-592, 2017. (Epub 2016 Aug 22)

Dougados, M, van der Heijde, D, Sieper, J, Braun, J, Citera, G, Lenaerts, J, van den Bosch, F, Wei, JC, Pedersen, R, Bonin, R, Jones, H, Marshall, L, Logeart, I, Vlahos, B, Bukowski, JF, Maksymowych, WP.
Effects of Long-Term Etanercept Treatment on Clinical Outcomes and Objective Signs of Inflammation in Early Nonradiographic Axial Spondyloarthritis: 104-Week Results From a Randomized, Placebo-Controlled Study
Arthritis Care Res (Hoboken) 69, 1590-1598, 2017. (Epub 2017 Aug 31)

Favreau, M, Menu, E, Gaublomme, D, Vanderkerken, K, Faict, S, Maes, K, De Bruyne, E, Govindarajan, S, Drennan, M, Van Calenbergh, S, Leleu, X, Zabeau, L, Tavernier, J, Venken, K, Elewaut, D.
Leptin receptor antagonism of iNKT cell function: a novel strategy to combat multiple myeloma
Leukemia 31, 2678-2685, 2017. (Epub 2017 May 11)

Favreau, M, Venken, K, Faict, S, Maes, K, De Veirman, K, De Bruyne, E, Leleu, X, Boon, L, Elewaut, D, Vanderkerken, K, Menu, E.
Both mucosal- associated invariant and natural killer T cell deficiency in multiple myeloma can be countered by PD-1 inhibition
Haematologica 102, E266-E270, 2017. (Epub 2017 Apr 6)

Guillaume, J, Seki, T, Decruy, T, Venken, K, Elewaut, D, Tsuji, M, Van Calenbergh, S.
Synthesis of C6''-modified alpha-C-GalCer analogues as mouse and human iNKT cell agonists
Org Biomol Chem 15, 2217-2225, 2017. (Epub 2017 Feb 21)

Guillaume, J, Wang, J, Janssens, J, Remesh, SG, Risseeuw, MDP, Decruy, T, Froeyen, M, Elewaut, D, Zajonc, DM, Calenbergh, SV.
Galactosylsphingamides: new alpha-GalCer analogues to probe the F'-pocket of CD1d
Sci Rep 7, 4276, 2017. (Epub 2017 Jun 27)

Herregods, N, Dehoorne, J, Van den Bosch, F, Jaremko, JL, Van Vlaenderen, J, Joos, R, Baraliakos, X, Varkas, G, Verstraete, K, Elewaut, D, Jans, L.
ASAS definition for sacroiliitis on MRI in SpA: applicable to children?
Pediatr Rheumatol 15, 24, 2017. (Epub 2017 Apr 11)

Back to previous page

Export in CSV

Page 1 of 3
<< 1 - 2 - 3 >>

To top

What do these icons mean?

pdf file (800 kb)