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Goossens, S, Wang, J, Tremblay, C, De Medts, J, T'Sas, S, Nguyen, T, Saw, J, Haigh, K, Curtis, DJ, Van Vlierberghe, P, Berx, G, Taghon, T, Haigh, JJ.
ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms
Haematologica , in press, 2019. (Epub 2019 Jan 24)

Haensel, D, Sun, P, MacLean, AL, Ma, X, Zhou, Y, Stemmler, MP, Brabletz, S, Berx, G, Plikus, MV, Nie, Q, Brabletz, T, Dai, X.
An Ovol2-Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation
EMBO Rep 20, e46273, 2019. (Epub 2018 Nov 9)

Jin, Q, Martinez, CA, Arcipowski, KM, Zhu, Y, Gutierrez-Diaz, BT, Wang, KK, Johnson, MR, Volk, A, Wang, F, Wu, J, Grove, C, Wang, H, Sokirniy, I, Thomas, PM, Goo, YA, et al., Vandamme, N, Berx, G, Goossens, S, et al..
USP7 cooperates with NOTCH1 to drive the oncogenic transcriptional program in T cell leukemia
Clin Cancer Res 25, 222-239, 2019. (Epub 2018 Sep 17)

Bouhy, D, Juneja, M, Katona, I, Holmgren, A, Asselbergh, B, De Winter, V, Hochepied, T, Goossens, S, Haigh, JJ, Libert, C, Ceuterick-de Groote, C, Irobi, J, Weis, J, Timmerman, V.
A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8
Acta Neuropathol 135, 131-148, 2018. (Epub 2017 Aug 5)

De Jaeghere, E, De Vlieghere, E, Van Hoorick, J, Van Vlierberghe, S, Wagemans, G, Pieters, L, Melsens, E, Praet, M, Van Dorpe, J, Boone, MN, Ghobeira, R, De Geyter, N, Bracke, M, Vanhove, C, Neyt, S, Berx, G, De Geest, BG, Dubruel, P, Declercq, H, et al..
Heterocellular 3D scaffolds as biomimetic to recapitulate the tumor microenvironment of peritoneal metastases in vitro and in vivo
Biomaterials 158, 95-105, 2018. (Epub 2017 Dec 23)

De Keuckelaere, E, Hulpiau, P, Saeys, Y, Berx, G, van Roy, F.
Nanos genes and their role in development and beyond
Cell Mol Life Sci 75, 1929-1946, 2018. (Epub 2018 Feb 3)

El Ashkar, S, Schwaller, J, Pieters, T, Goossens, S, Demeulemeester, J, Christ, F, Van Belle, S, Juge, S, Boeckx, N, Engelman, A, Van Vlierberghe, P, Debyser, Z, De Rijck, J.
LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis
Blood 131, 95-107, 2018. (Epub 2017 Oct 30)

Milani, G, Matthijssens, F, Van Loocke, W, Durinck, K, Roels, J, Peirs, S, Thenoz, M, Pieters, T, Reunes, L, Lintermans, B, Vandamme, N, Lammens, T, Van Roy, N, Van Nieuwerburgh, F, Deforce, D, Schwab, C, Raimondi, S, Dalla Pozza, L, Carroll, AJ, 3rd, et al..
Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia
Br J Haematol , in press, 2018. (Epub 2018 Jun 25)

Renard, M, Vanhauwaert, S, Vanhomwegen, M, Rihani, A, Vandamme, N, Goossens, S, Berx, G, Van Vlierberghe, P, Haigh, JJ, Decaesteker, B, Van Laere, J, Lambertz, I, Speleman, F, Vandesompele, J, Willaert, A.
Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice
Sci Rep 8, 7642, 2018. (Epub 2018 May 16)

Scott, CL, T'Jonck, W, Martens, L, Todorov, H, Sichien, D, Soen, B, Bonnardel, J, De Prijck, S, Vandamme, N, Cannoodt, R, Saelens, W, Vanneste, B, Toussaint, W, De Bleser, P, Takahashi, N, Vandenabeele, P, et al., Lambrecht, BN, De Baetselier, P, Milling, SWF, Van Ginderachter, JA, Malissen, B, Berx, G, Beschin, A, Saeys, Y, Guilliams, M.
The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages
Immunity 49, 312-325, 2018. (Epub 2018 Jul 31)

Skrypek, N, Bruneel, K, Vandewalle, C, De Smedt, E, Soen, B, Loret, N, Taminau, J, Goossens, S, Vandamme, N, Berx, G.
ZEB2 stably represses RAB25 expression through epigenetic regulation by SIRT1 and DNMTs during epithelial-to-mesenchymal transition
Epigenetics Chromatin 11, 70, 2018. (Epub 2018 Nov 16)

Consortium, E-T, Van Deun, J, Mestdagh, P, Agostinis, P, Akay, O, Anand, S, Anckaert, J, Martinez, ZA, Baetens, T, Beghein, E, Bertier, L, Berx, G, Boere, J, al., E, De Smedt, E, al., E, Soen, B, al., E, Van Vliet, AR, Vandamme, N, et al..
EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research
Nat Methods 14, 228-232, 2017. (Epub 2017 Feb 28)

Devos, M, Gilbert, B, Denecker, G, Leurs, K, Mc Guire, C, Lemeire, K, Hochepied, T, Vuylsteke, M, Lambert, J, Van Den Broecke, C, Libbrecht, L, Haigh, J, Berx, G, Lippens, S, Vandenabeele, P, Declercq, W.
Elevated DeltaNp63alpha levels facilitate epidermal and biliary oncogenic transformation
J Invest Dermatol 137, 494-505, 2017. (Epub 2016 Oct 7)

Goossens, S, Peirs, S, Van Loocke, W, Wang, J, Takawy, M, Matthijssens, F, Sonderegger, SE, Haigh, K, Nguyen, T, Vandamme, N, Costa, M, Carmichael, C, Van Nieuwerburgh, F, Deforce, D, Kleifeld, O, Curtis, DJ, Berx, G, Van Vlierberghe, P, Haigh, JJ.
Oncogenic ZEB2 activation drives sensitivity towards KDM1A inhibition in T-cell acute lymphoblastic leukemia
Blood 129, 981-990, 2017. (Epub 2017 Jan 9)

Goossens, S, Vandamme, N, Van Vlierberghe, P, Berx, G.
EMT transcription factors in cancer development re-evaluated: Beyond EMT and MET
Biochim Biophys Acta 1868, 584-591, 2017. (Epub 2017 Jun 29)

Kohler, C, Nittner, D, Rambow, F, Radaelli, E, Stanchi, F, Vandamme, N, Baggiolini, A, Sommer, L, Berx, G, van den Oord, JJ, Gerhardt, H, Blanpain, C, Marine, JC.
Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes
Cell Stem Cell 21, 679-693, 2017. (Epub 2017 Oct 12)

Li, J, Riedt, T, Goossens, S, Carrillo Garcia, C, Szczepanski, S, Brandes, M, Pieters, T, Dobrosch, L, Gutgemann, I, Farla, N, Radaelli, E, Hulpiau, P, Mallela, N, Frohlich, H, La Starza, R, Matteucci, C, Chen, T, Brossart, P, Mecucci, C, et al..
The EMT transcription factor Zeb2 controls adult murine hematopoietic differentiation by regulating cytokine signaling
Blood 129, 460-472, 2017. (Epub 2016 Sep 28)

Peirs, S, Frismantas, V, Matthijssens, F, Van Loocke, W, Pieters, T, Vandamme, N, Lintermans, B, Dobay, MP, Berx, G, Poppe, B, Goossens, S, Bornhauser, BC, Bourquin, JP, Van Vlierberghe, P.
Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia
Leukemia 31, 2037-2047, 2017. (Epub 2017 Feb 3 )

Pieters, T, Haenebalcke, L, Bruneel, K, Vandamme, N, Hochepied, T, van Hengel, J, Wirth, D, Berx, G, Haigh, JJ, van Roy, F, Goossens, S.
Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange
J Vis Exp , 122, 2017. (Epub 2017 Apr 27)

Skrypek, N, Goossens, S, De Smedt, E, Vandamme, N, Berx, G.
Epithelial-to-Mesenchymal Transition: Epigenetic Reprogramming Driving Cellular Plasticity
Trends Genet 33, 943-959, 2017. (Epub 2017 Sep 14)

Stryjewska, A, Dries, R, Pieters, T, Verstappen, G, Conidi, A, Coddens, K, Francis, A, Umans, L, van, IWF, Berx, G, van Grunsven, LA, Grosveld, F, Goossens, S, Haigh, JJ, Huylebroeck, D.
Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells
Stem Cells 35, 611-625, 2017. (Epub 2016 Oct 14)

Vergauwen, G, Dhondt, B, Van Deun, J, De Smedt, E, Berx, G, Timmerman, E, Gevaert, K, Miinalainen, I, Cocquyt, V, Braems, G, Van den Broecke, R, Denys, H, De Wever, O, Hendrix, A.
Confounding factors of ultrafiltration and protein analysis in extracellular vesicle research
Sci Rep 7, 2704, 2017. (Epub 2017 Jun 2)

Aaes, TL, Kaczmarek, A, Delvaeye, T, De Craene, B, De Koker, S, Heyndrickx, L, Delrue, I, Taminau, J, Wiernicki, B, De Groote, P, Garg, AD, Leybaert, L, Grooten, J, Bertrand, MJ, Agostinis, P, Berx, G, Declercq, W, Vandenabeele, P, Krysko, DV.
Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity
Cell Rep 15, 274-287, 2016. (Epub 2016 Mar 30)

Bouhy, D, Geuens, T, De Winter, V, Almeida-Souza, L, Katona, I, Weis, J, Hochepied, T, Goossens, S, Haigh, J, Janssens, S, Timmerman, V.
Characterization of New Transgenic Mouse Models for Two Charcot-Marie-Tooth-Causing HspB1 Mutations using the Rosa26 Locus
Journal of Neuromuscular Diseases 3, 183-200, 2016. (Epub 2016 May 27)

Bourcy, M, Suarez-Carmona, M, Lambert, J, Francart, ME, Schroeder, H, Delierneux, C, Skrypek, N, Thompson, EW, Jerusalem, G, Berx, G, Thiry, M, Blacher, S, Hollier, BG, Noel, A, Oury, C, Polette, M, Gilles, C.
Tissue factor induced by epithelial-mesenchymal transition triggers a pro-coagulant state that drives metastasis of circulating tumor cells
Cancer Res 76, 4270-4282, 2016. (Epub 2016 May 24)

Goossens, S, Van Vlierberghe, P.
Overcoming Steroid Resistance in T Cell Acute Lymphoblastic Leukemia
PLoS Med 13, e1002208, 2016. (Epub 2016 Dec 20)

Helsmoortel, HH, De Moerloose, B, Pieters, T, Ghazavi, F, Bresolin, S, Cave, H, de Vries, A, de Haas, V, Flotho, C, Labarque, V, Niemeyer, C, De Paepe, P, Van Roy, N, Stary, J, van den Heuvel-Eibrink, MM, Benoit, Y, Schulte, J, Goossens, S, Berx, G, et al., Van Vlierberghe, P, Lammens, T.
LIN28B is over-expressed in specific subtypes of paediatric leukaemia and regulates lncRNA H19
Haematologica 101, E240-E244, 2016. (Epub 2016 Mar 11)

Pieters, T, Goossens, S, Haenebalcke, L, Andries, V, Stryjewska, A, De Rycke, R, Lemeire, K, Hochepied, T, Huylebroeck, D, Berx, G, Stemmler, MP, Wirth, D, Haigh, JJ, van Hengel, J, van Roy, F.
p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification
PLoS Genet 12, e1006243, 2016. (Epub 2016 Aug 24)

Scott, CL, Soen, B, Martens, L, Skrypek, N, Saelens, W, Taminau, J, Blancke, G, Van Isterdael, G, Huylebroeck, D, Haigh, J, Saeys, Y, Guilliams, M, Lambrecht, BN, Berx, G.
The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2
J Exp Med 213, 897-911, 2016. (Epub 2016 May 16)

Andries, V, Vandepoele, K, Staes, K, Berx, G, Bogaert, P, Van Isterdael, G, Ginneberge, D, Parthoens, E, Vandenbussche, J, Gevaert, K, van Roy, F.
NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest
BMC Cancer 15, 391, 2015. (Epub 2015 May 10)

Ballantyne, LL, Sin, YY, St Amand, T, Si, J, Goossens, S, Haenebalcke, L, Haigh, JJ, Kyriakopoulou, L, Schulze, A, Funk, CD.
Strategies to rescue the consequences of inducible arginase-1 deficiency in mice
PLoS One 10, e0125967, 2015. (Epub 2015 May 4)

De Vlieghere, E, Gremonprez, F, Verset, L, MariŽn, L, Jones, CJ, De Craene, B, Berx, G, Descamps, B, Vanhove, C, Remon, J-P, Ceelen, W, Demetter, P, Bracke, M, De Geest, BG, De Wever, O.
Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells
Biomaterials 54, 148-157, 2015. (Epub 2015 Mar 4)

Durinck, K, Goossens, S, Peirs, S, Wallaert, A, Van Loocke, W, Matthijssens, F, Pieters, T, Milani, G, Lammens, T, Rondou, P, Van Roy, N, De Moerloose, B, Benoit, Y, Haigh, J, Speleman, F, Poppe, B, Van Vlierberghe, P.
Novel biological insights in T-cell acute lymphoblastic leukemia
Exp Hematol 43, 625-639, 2015. (Epub 2015 Jun 26)

Goossens, S, Radaelli, E, Blanchet, O, Durinck, K, Van der Meulen, J, Peirs, S, Taghon, T, Tremblay, CS, Costa, M, Farhang Ghahremani, M, De Medts, J, Bartunkova, S, Haigh, K, Schwab, C, Farla, N, Pieters, T, Matthijssens, F, Van Roy, N, Best, JA, et al..
ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling
Nat Commun 6, 5794, 2015. (Epub 2015 Jan 7)

Horvay, K, Jarde, T, Casagranda, F, Perreau, VM, Haigh, K, Nefzger, CM, Akhtar, R, Gridley, T, Berx, G, Haigh, JJ, Barker, N, Polo, JM, Hime, GR, Abud, HE.
Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium
EMBO J 34, 1319-1335, 2015. (Epub 2015 Mar 10)

Omilusik, KD, Best, JA, Yu, B, Goossens, S, Weidemann, A, Nguyen, JV, Seuntjens, E, Stryjewska, A, Zweier, C, Roychoudhuri, R, Gattinoni, L, Bird, LM, Higashi, Y, Kondoh, H, Huylebroeck, D, Haigh, J, Goldrath, AW.
Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection
J Exp Med 212, 2027-2039, 2015. (Epub 2015 Oct 26)

Ramboer, E, De Craene, B, De Kock, J, Berx, G, Rogiers, V, Vanhaecke, T, Vinken, M.
Development and chararcterization of a new human hepatic cell line
Excli Journal 14, 875-889, 2015. (Epub 2015 Jul 28)

Van der Meulen, J, Sanghvi, V, Mavrakis, K, Durinck, K, Fang, F, Matthijssens, F, Rondou, P, Rosen, M, Pieters, T, Vandenberghe, P, Delabesse, E, Lammens, T, De Moerloose, B, Menten, B, Van Roy, N, Verhasselt, B, Poppe, B, Benoit, Y, Taghon, T, et al..
The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia
Blood 125, 13-21, 2015. (Epub 2014 Oct 15)

van Helden, MJ, Goossens, S, Daussy, C, Mathieu, AL, Faure, F, Marcais, A, Vandamme, N, Farla, N, Mayol, K, Viel, S, Degouve, S, Debien, E, Seuntjens, E, Conidi, A, Chaix, J, Mangeot, P, de Bernard, S, Buffat, L, Haigh, JJ, et al..
Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection
J Exp Med 212, 2015-2025, 2015. (Epub 2015 Oct 26)

Castiglioni, V, Farhang Ghahremani, M, Goossens, S, De Maglie, M, Ardizzone, M, Haigh, JJ, Radaelli, E.
Immunohistological description of nongestational ovarian choriocarcinoma in two female mice with conditional loss of Trp53 driven by the Tie2 promoter
Vet Pathol 52, 752-756, 2014. (Epub 2014 Sep 24)

De Craene, B, Denecker, G, Vermassen, P, Taminau, J, Mauch, C, Derore, A, Jonkers, J, Fuchs, E, Berx, G.
Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential
Cell Death Differ 21, 310-320, 2014. (Epub 2013 Oct 25)

De Groote, P, Tran, HT, Fransen, M, Tanghe, G, Urwyler, C, De Craene, B, Leurs, K, Gilbert, B, Van Imschoot, G, De Rycke, R, Guerin, CJ, Holland, P, Berx, G, Vandenabeele, P, Lippens, S, Vleminckx, K, Declercq, W.
A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes
Cell Death Differ 22, 1012-1024, 2014. (Epub 2014 Nov 28)

Denecker, G, Vandamme, N, Akay, Ö, Koludrovic, D, Taminau, J, Lemeire, K, Gheldof, A, De Craene, B, Van Gele, M, Brochez, L, Udupi, G, Rafferty, M, Balint, B, Gallagher, WM, Ghanem, G, Huylebroeck, D, Haigh, JJ, van den Oord, J, Larue, L, Davidson, I, Marine, JC, Berx, G.
Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression
Cell Death Differ 21, 1250-1261, 2014. (Epub 2014 Apr 25)

Farhang Ghahremani, M, Radaelli, E, Haigh, K, Bartunkova, S, Haenebalcke, L, Marine, JC, Goossens, S, Haigh, JJ.
Loss of autocrine endothelial-derived VEGF significantly reduces hemangiosarcoma development in conditional p53-deficient mice
Cell Cycle 13, 1501-1507, 2014. (Epub 2014 Mar 11)

Goossens, S, Van Vlierberghe, P.
Controlling Pre-leukemic Thymocyte Self-Renewal
PLoS Genet 10, e1004881, 2014. (Epub 2014 Dec 18)

Mets, E, Van der Meulen, J, Van Peer, G, Boice, M, Mestdagh, P, Van de Walle, I, Lammens, T, Goossens, S, De Moerloose, B, Benoit, Y, Van Roy, N, Clappier, E, Poppe, B, Vandesompele, J, Wendel, HG, Taghon, T, Rondou, P, Soulier, J, Van Vlierberghe, P, Speleman, F.
MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia
Leukemia 29, 798-806, 2014. (Epub 2014 Sep 18)

Mets, E, Van Peer, G, Van der Meulen, J, Boice, M, Taghon, T, Goossens, S, Mestdagh, P, Benoit, Y, De Moerloose, B, Van Roy, N, Poppe, B, Vandesompele, J, Wendel, HG, Van Vlierberghe, P, Speleman, F, Rondou, P.
MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia
Haematologica 99, 1326-1333, 2014. (Epub 2014 Jun 3)

Peirs, S, Matthijssens, F, Goossens, S, Van de Walle, I, Ruggero, K, de Bock, CE, Degryse, S, Cante-Barrett, K, Briot, D, Clappier, E, Lammens, T, De Moerloose, B, Benoit, Y, Poppe, B, Meijerink, J, Cools, J, Soulier, J, Rabbitts, TH, Taghon, T, Speleman, F, Van Vlierberghe, P.
ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia
Blood 124, 3738-3747, 2014. (Epub 2014 Oct 9)

Quimbaya, M, Raspe, E, Denecker, G, De Craene, B, Roelandt, R, Declercq, W, Sagaert, X, De Veylder, L, Berx, G.
Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability
Neoplasia 16, 694-709, 2014. (Epub 2014 Sep)

Ramboer, E, De Craene, B, De Kock, J, Vanhaecke, T, Berx, G, Rogiers, V, Vinken, M.
Strategies for immortalization of primary hepatocytes
J Hepatol 61, 925-943, 2014. (Epub 2014 Jun 6)

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