» Home » Research 
Print this pageEmail this page URLConvert this page to PDF

Publications from this research unit

This page shows only publications with IRC as the affiliation of at least one author.
Publications by IRC members mentioning other affiliations are not in our database. Sorry.
See "Extra muros" papers of the units.

For copyright reasons, PDF-versions of our publications are available on the intranet only (login required  ). If you would like to receive a reprint of an IRC paper, please copy/paste the reference in the
reprint request form 

Gorle, N, Bauwens, E, Haesebrouck, F, Smet, A, Vandenbroucke, RE.
Helicobacter and the Potential Role in Neurological Disorders: There Is More Than Helicobacter pylori
Front Immunol 11, 584165, 2021. (Epub 2021 Jan 28)

Bos, S, Laukens, D.
Metabolic modulation during intestinal fibrosis
J Dig Dis , in press, 2020. (Epub 2020 May 14)

Grigoryan, R, Costas-Rodriguez, M, Vandenbroucke, RE, Vanhaecke, F.
High-precision isotopic analysis of Mg and Ca in biological samples using multi-collector ICP-mass spectrometry after their sequential chromatographic isolation - Application to the characterization of the body distribution of Mg and Ca isotopes in mice
Anal Chim Acta 1130, 137-145, 2020. (Epub 2020 Jul 28)

Lefevere, E, Salinas-Navarro, M, Andries, L, Noterdaeme, L, Etienne, I, Van Wonterghem, E, Vinckier, S, Davis, BM, Van Bergen, T, Van Hove, I, Movahedi, K, Vandenbroucke, RE, Moons, L, De Groef, L.
Tightening the retinal glia limitans attenuates neuroinflammation after optic nerve injury
Glia 68, 2643-2660, 2020. (Epub 2020 Jul 9)

Vandendriessche, C, Bruggeman, A, Van Cauwenberghe, C, Vandenbroucke, RE.
Extracellular Vesicles in Alzheimer's and Parkinson's Disease: Small Entities with Large Consequences
Cells 9, 2485, 2020. (Epub 2020 Nov 15)

van Olst, L, Verhaege, D, Franssen, M, Kamermans, A, Roucourt, B, Carmans, S, Ytebrouck, E, van der Pol, SMA, Wever, D, Popovic, M, Vandenbroucke, RE, Sobrino, T, Schouten, M, de Vries, HE.
Microglial activation arises after aggregation of phosphorylated-tau in a neuron-specific P301S tauopathy mouse model
Neurobiol Aging 89, 89-98, 2020. (Epub 2020 Jan 10)

Ballegeer, M, Vandewalle, J, Eggermont, M, Van Isterdael, G, Dejager, L, De Bus, L, Decruyenaere, J, Vandenbroucke, RE, Libert, C.
Overexpression of Gilz Protects Mice Against Lethal Septic Peritonitis
Shock 52, 208-214, 2019. (Epub 2018 Aug 17)

Coenen-Stass, AML, Pauwels, MJ, Hanson, B, Martin Perez, C, Conceicao, M, Wood, MJA, Mager, I, Roberts, TC.
Extracellular microRNAs exhibit sequence-dependent stability and cellular release kinetics
RNA Biol 16, 696-706, 2019. (Epub 2019 Mar 5)

Delvaeye, T, De Smet, MAJ, Verwaerde, S, Decrock, E, Czekaj, A, Vandenbroucke, RE, Lemeire, K, Goncalves, A, Declercq, W, Vandenabeele, P, Krysko, DV, Leybaert, L.
Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock
Sci Rep 9, 16623, 2019. (Epub 2019 Nov 12)

Gorle, N, Vandenbroucke, RE.
Interferons: A molecular switch between damage and repair in ageing and Alzheimer's disease
Mech Ageing Dev 183, 111148, 2019. (Epub 2019 Sep 18)

Lepko, T, Pusch, M, Muller, T, Schulte, D, Ehses, J, Kiebler, M, Hasler, J, Huttner, HB, Vandenbroucke, RE, Vandendriessche, C, Modic, M, Martin-Villalba, A, Zhao, S, E, LL-B, Schneider, A, Fischer, A, Breunig, CT, Stricker, SH, Gotz, M, et al..
Choroid plexus-derived miR-204 regulates the number of quiescent neural stem cells in the adult brain
EMBO J , e100481, 2019. (Epub 2019 Jul 15)

Naessens, S, De Zaeytijd, J, Syx, D, Vandenbroucke, RE, Smeets, F, Van Cauwenbergh, C, Leroy, BP, Peelman, F, Coppieters, F.
The N-terminal p.(Ser38Cys) TIMP3 mutation underlying Sorsby fundus dystrophy is a founder mutation disrupting an intramolecular disulfide bond
Hum Mutat 40, 539-551, 2019. (Epub 2019 Feb 6)

Russell, AE, Sneider, A, Witwer, KW, Bergese, P, Bhattacharyya, SN, Cocks, A, Cocucci, E, Erdbrugger, U, Falcon-Perez, JM, Freeman, DW, Gallagher, TM, Hu, S, Huang, Y, Jay, SM, Kano, SI, Lavieu, G, Leszczynska, A, Llorente, AM, Lu, Q, et al..
Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop
J Extracell Vesicles 8, 1684862, 2019. (Epub 2019 Nov 8)

Steeland, S, Vandenbroucke, RE.
Choroid plexus tumor necrosis factor receptor 1: A new neuroinflammatory piece of the complex Alzheimer's disease puzzle
Neural Regen Res 14, 1144-1147, 2019. (Epub 2019 Feb 26)

Vandewalle, J, Steeland, S, Van Ryckeghem, S, Eggermont, M, Van Wonterghem, E, Vandenbroucke, RE, Libert, C.
A Study of Cecal Ligation and Puncture-Induced Sepsis in Tissue-Specific Tumor Necrosis Factor Receptor 1-Deficient Mice
Front Immunol 10, 2574, 2019. (Epub 2019 Nov 8)

Van Hove, H, Martens, L, Scheyltjens, I, De Vlaminck, K, Pombo Antunes, AR, De Prijck, S, Vandamme, N, De Schepper, S, Van Isterdael, G, Scott, CL, Aerts, J, Berx, G, Boeckxstaens, GE, Vandenbroucke, RE, Vereecke, L, Moechars, D, Guilliams, M, Van Ginderachter, JA, Saeys, Y, Movahedi, K.
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
Nat Neurosci 22, 1021–1035, 2019. (Epub 2019 May 6)

Zhong, Z, Portela Catani, JP, Mc Cafferty, S, Couck, L, Van Den Broeck, W, Gorle, N, Vandenbroucke, RE, Devriendt, B, Ulbert, S, Cnops, L, Michels, J, Arien, KK, Sanders, NN.
Immunogenicity and Protection Efficacy of a Naked Self-Replicating mRNA-Based Zika Virus Vaccine
Vaccines (Basel) 7, 96, 2019. (Epub 2019 Aug 23)

Ballegeer, M, Van Looveren, K, Timmermans, S, Eggermont, M, Vandevyver, S, Thery, F, Dendoncker, K, Souffriau, J, Vandewalle, J, Van Wyngene, L, De Rycke, R, Takahashi, N, Vandenabeele, P, Tuckermann, J, Reichardt, HM, Impens, F, Beyaert, R, De Bosscher, K, Vandenbroucke, RE, et al..
Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice
J Clin Invest 128, 3265-3279, 2018. (Epub 2018 May 10)

Gorle, N, Blaecher, C, Bauwens, E, Vandendriessche, C, Balusu, S, Vandewalle, J, Van Cauwenberghe, C, Van Wonterghem, E, Van Imschoot, G, Liu, C, Ducatelle, R, Libert, C, Haesebrouck, F, Smet, A, Vandenbroucke, RE.
The choroid plexus epithelium as a novel player in the stomach-brain axis during Helicobacter infection
Brain Behav Immun 69, 35-47, 2018. (Epub 2017 Dec 16)

Steeland, S, Gorle, N, Vandendriessche, C, Balusu, S, Brkic, M, Van Cauwenberghe, C, Van Imschoot, G, Van Wonterghem, E, De Rycke, R, Kremer, A, Lippens, S, Stopa, E, Johanson, CE, Libert, C, Vandenbroucke, RE.
Counteracting the effects of TNF receptor-1 has therapeutic potential in Alzheimer's disease
EMBO Mol Med 10, UNSP e8300, 2018. (Epub 2018 Feb 22)

Steeland, S, Libert, C, Vandenbroucke, RE.
A New Venue of TNF Targeting
Int J Mol Sci 19, e1442, 2018. (Epub 2018 May 11)

Steeland, S, Van Ryckeghem, S, Vandewalle, J, Ballegeer, M, Van Wonterghem, E, Eggermont, M, Decruyenaere, J, De Bus, L, Libert, C, Vandenbroucke, RE.
Simultaneous Inhibition of Tumor Necrosis Factor Receptor 1 and Matrix Metalloproteinase 8 Completely Protects Against Acute Inflammation and Sepsis
Crit Care Med 46, e67–e75, 2018. (Epub 2017 Oct 31)

Voet, S, Mc Guire, C, Hagemeyer, N, Martens, A, Schroeder, A, Wieghofer, P, Daems, C, Staszewski, O, Vande Walle, L, Jordao, MJC, Sze, M, Vikkula, HK, Demeestere, D, Van Imschoot, G, Scott, CL, Hoste, E, Goncalves, A, Guilliams, M, Lippens, S, Libert, C, Vandenbroucke, RE, et al., Lamkanfi, M, Prinz, M, van Loo, G.
A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation
Nat Commun 9, 2036, 2018. (Epub 2018 May 23)

Zagato, E, Vermeulen, L, Dewitte, H, Van Imschoot, G, Vandenbroucke, RE, Demeester, J, De Schmedt, SC, Neyts, K, Remaut, K, Braeckmans, K.
Quantifying the average number of nucleic acid therapeutics per nanocarrier by Single Particle Tracking microscopy
Mol Pharm 15, 1142-1149, 2018. (Epub 2018 Feb 12)

Greenwood, J, Hammarlund-Udenaes, M, Jones, HC, Stitt, AW, Vandenbroucke, RE, Romero, IA, Campbell, M, Fricker, G, Brodin, B, Manninga, H, Gaillard, PJ, Schwaninger, M, Webster, C, Wicher, KB, Khrestchatisky, M.
Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017
Fluids Barriers CNS 14, 31, 2017. (Epub 2017 Nov 7)

Holvoet, T, Devriese, S, Castermans, K, Boland, S, Leysen, D, Vandewynckel, YP, Devisscher, L, Van den Bossche, L, Van Welden, S, Dullaers, M, Vandenbroucke, RE, De Rycke, R, Geboes, K, Bourin, A, Defert, O, Hindryckx, P, De Vos, M, Laukens, D.
Treatment of intestinal fibrosis in experimental inflammatory bowel disease by the pleiotropic actions of a local Rho kinase inhibitor
Gastroenterology 153, 1054-1067, 2017. (Epub 2017 Jun 19)

Steeland, S, Van Ryckeghem, S, Van Imschoot, G, De Rycke, R, Toussaint, W, Vanhoutte, L, Vanhove, C, De Vos, F, Vandenbroucke, RE, Libert, C.
TNFR1 inhibition with a Nanobody protects against EAE development in mice
Sci Rep 7, 13646, 2017. (Epub 2017 Oct 20)

Balusu, S, Brkic, M, Libert, C, Vandenbroucke, RE.
The choroid plexus-cerebrospinal fluid interface in Alzheimer's disease: more than just a barrier
Neural Regen Res 11, 534-537, 2016. (Epub 2016 Apr)

Balusu, S, Van Wonterghem, E, De Rycke, R, Raemdonck, K, Stremersch, S, Gevaert, K, Brkic, M, Demeestere, D, Vanhooren, V, Hendrix, A, Libert, C, Vandenbroucke, RE.
Identification of a novel mechanism of blood-brain communication during peripheral inflammation via choroid plexus-derived extracellular vesicles
EMBO Mol Med 8, 1162-1183, 2016. (Epub 2016 Oct 4)

De Bock, M, Van Haver, V, Vandenbroucke, RE, Decrock, E, Wang, N, Leybaert, L.
Into rather unexplored terrain-transcellular transport across the blood-brain barrier
Glia 64, 1097-1123, 2016. (Epub 2016 Feb 8)

Demeestere, D, Dejonckheere, E, Steeland, S, Hulpiau, P, Haustraete, J, Devoogdt, N, Wichert, R, Becker-Pauly, C, Van Wonterghem, E, Dewaele, S, Van Imschoot, G, Aerts, J, Arckens, L, Saeys, Y, Libert, C, Vandenbroucke, RE.
Development and validation of a small single domain antibody that effectively inhibits matrix metalloproteinase 8
Mol Ther 24, 890-902, 2016. (Epub 2016 Jan 18)

Drechsler, S, Lynch, MA, Novella, S, Gonzalez-Navarro, H, Hecimovic, S, Barini, E, Tucci, V, Castro, RE, Vandenbroucke, RE, Osuchowski, M, Potter, PK.
With mouse age comes wisdom: a review and suggestions of relevant mouse models for age-related conditions
Mech Ageing Dev 160, 54-68, 2016. (Epub 2016 Jul 20)

Gorlé, N, Van Cauwenberghe, C, Libert, C, Vandenbroucke, RE.
The effect of aging on brain barriers and the consequences for Alzheimer's disease development
Mamm Genome 27, 407-420, 2016. (Epub 2016 May 3)

Grine, L, Libert, C, Vandenbroucke, R.
Comment on "Tumour necrosis factor alpha plays a significant role in the Aldara-induced skin inflammation in mice"
Br J Dermatol 174, 1419-1419, 2016. (Epub 2016 Feb 6)

Grine, L, Steeland, S, Van Ryckeghem, S, Ballegeer, M, Lienenklaus, S, Weiss, S, Sanders, NN, Vandenbroucke, RE, Libert, C.
Topical imiquimod yields systemic effects due to unintended oral uptake
Sci Rep 6, 20134, 2016. (Epub 2016 Jan 28)

Kessler, SM, Laggai, S, Van Wonterghem, E, Gemperlein, K, Muller, R, Haybaeck, J, Vandenbroucke, RE, Ogris, M, Libert, C, Kiemer, AK.
Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation
Front Physiol 7, 147, 2016. (Epub 2016 Apr 25)

Koks, S, Dogan, S, Tuna, BG, Gonzalez-Navarro, H, Potter, P, Vandenbroucke, RE.
Mouse models of ageing and their relevance to disease
Mech Ageing Dev 160, 41-53, 2016. (Epub 2016 Oct 4)

Steeland, S, Timmermans, S, Van Ryckeghem, S, Hulpiau, P, Saeys, Y, Van Montagu, M, Vandenbroucke, RE, Libert, C.
Efficient analysis of mouse genome sequences reveal many nonsense variants
Proc Natl Acad Sci U S A 113, 5670-5675, 2016. (Epub 2016 May 17)

Steeland, S, Vandenbroucke, RE, Libert, C.
Nanobodies as therapeutics: big opportunities for small antibodies
Drug Discov Today 21, 1076-1113, 2016. (Epub 2016 Apr 11)

Storck, SE, Meister, S, Nahrath, J, Meissner, JN, Schubert, N, Di Spiezio, A, Baches, S, Vandenbroucke, RE, Bouter, Y, Prikulis, I, Korth, C, Weggen, S, Heimann, A, Schwaninger, M, Bayer, TA, Pietrzik, CU.
Endothelial LRP1 transports amyloid-beta1-42 across the blood-brain barrier
J Clin Invest 126, 123-136, 2016. (Epub 2015 Nov 30)

Stremersch, S, Vandenbroucke, RE, Van Wonterghem, E, Hendrix, A, De Smedt, SC, Raemdonck, K.
Comparing exosome-like vesicles with liposomes for the functional cellular delivery of small RNAs
J Control Release 232, 51-61, 2016. (Epub 2016 Apr 9)

Van Cauwenberghe, C, Vandendriessche, C, Libert, C, Vandenbroucke, RE.
Caloric restriction: beneficial effects on brain aging and Alzheimer's disease
Mamm Genome 27, 300-319, 2016. (Epub 2016 May 30)

Vandenbroucke, RE.
A Hidden Epithelial Barrier in the Brain with a Central Role in Regulating Brain Homeostasis. Implications for Aging
Ann Am Thorac Soc 13, S407-S410, 2016. (Epub 2016 Dec 13)

Van Hove, I, Lefevere, E, De Groef, L, Sergeys, J, Salinas-Navarro, M, Libert, C, Vandenbroucke, R, Moons, L.
MMP-3 Deficiency Alleviates Endotoxin-Induced Acute Inflammation in the Posterior Eye Segment
Int J Mol Sci 17, E1825, 2016. (Epub 2016 Nov 1)

Xiong, R, Vandenbroucke, RE, Broos, K, Brans, T, Van Wonterghem, E, Libert, C, Demeester, J, De Smedt, SC, Braeckmans, K.
Sizing nanomaterials in bio-fluids by cFRAP enables protein aggregation measurements and diagnosis of bio-barrier permeability
Nat Commun 7, 12982, 2016. (Epub 2016 Sep 22)

Aerts, J, Vandenbroucke, RE, Dera, R, Balusu, S, Van Wonterghem, E, Moons, L, Libert, C, Dehaen, W, Arckens, L.
Synthesis and Validation of a Hydroxypyrone-Based, Potent, and Specific Matrix Metalloproteinase-12 Inhibitor with Anti-Inflammatory Activity In Vitro and In Vivo
Mediators Inflamm 2015, 510679, 2015. (Epub 2015 Aug 13)

Brkic, M, Balusu, S, Libert, C, Vandenbroucke, RE.
Friends or Foes: Matrix Metalloproteinases and Their Multifaceted Roles in Neurodegenerative Diseases
Mediators Inflamm 2015, 620581, 2015. (Epub 2015 Oct 11)

Brkic, M, Balusu, S, Van Wonterghem, E, Gorle, N, Benilova, I, Kremer, A, Van Hove, I, Moons, L, De Strooper, B, Kanazir, S, Libert, C, Vandenbroucke, RE.
Amyloid beta Oligomers Disrupt Blood-CSF Barrier Integrity by Activating Matrix Metalloproteinases
J Neurosci 35, 12766-78, 2015. (Epub 2015 Sep 16)

De Groef, L, Salinas-Navarro, M, Van Imschoot, G, Libert, C, Vandenbroucke, RE, Moons, L.
Decreased TNF Levels and Improved Retinal Ganglion Cell Survival in MMP-2 Null Mice Suggest a Role for MMP-2 as TNF Sheddase
Mediators Inflamm 2015, 108617, 2015. (Epub 2015 Sep 15)

Demeestere, D, Libert, C, Vandenbroucke, RE.
Clinical implications of leukocyte infiltration at the choroid plexus in (neuro)inflammatory disorders
Drug Discov Today 20, 928-941, 2015. (Epub 2015 May 13)

Back to previous page

Export in CSV

Page 1 of 2
<< 1 - 2 >>

To top

What do these icons mean?

pdf file (800 kb)