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Devos, M, Mogilenko, DA, Fleury, S, Gilbert, B, Becquart, C, Quemener, S, Dehondt, H, Tougaard, P, Staels, B, Bachert, C, Vandenabeele, P, Van Loo, G, Staumont-Salle, D, Declercq, W, Dombrowicz, D.
Keratinocyte expression of A20/TNFAIP3 controls skin inflammation associated with atopic dermatitis and psoriasis
J Invest Dermatol 139, 135-145, 2019. (Epub 2018 Aug 14)

Deckers, J, Bougarne, N, Mylka, V, Desmet, S, Luypaert, A, Devos, M, Tanghe, G, Van Moorleghem, J, Vanheerswynghels, M, De Cauwer, L, Thommis, J, Vuylsteke, M, Tavernier, J, Lambrecht, B, Hammad, H, De Bosscher, K.
Co-activation of GR and PPARgamma in murine skin prevents worsening of atopic march
J Invest Dermatol 138, 1360-1370, 2018. (Epub 2017 Dec 27)

Tanghe, G, Urwyler-Rosselet, C, De Groote, P, Dejardin, E, De Bock, PJ, Gevaert, K, Vandenabeele, P, Declercq, W.
RIPK4 activity in keratinocytes is controlled by the SCF(beta-TrCP) ubiquitin ligase to maintain cortical actin organization
Cell Mol Life Sci 75, 2827-2841, 2018. (Epub 2018 Feb 12)

Teufelberger, AR, Nordengrun, M, Braun, H, Maes, T, De Grove, K, Holtappels, G, O'Brien, C, Provoost, S, Hammad, H, Goncalves, A, Beyaert, R, Declercq, W, Vandenabeele, P, Krysko, DV, Broker, BM, Bachert, C, Krysko, O.
The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D.
J Allergy Clin Immunol 141, 549-559, 2018. (Epub 2017 May 19)

Urwyler-Rosselet, C, Tanghe, G, Leurs, K, Gilbert, B, De Rycke, R, De Bruyne, M, Lippens, S, Bartunkova, S, De Groote, P, Niessen, C, Haftek, M, Vandenabeele, P, Declercq, W.
Keratinocyte-specific ablation of RIPK4 allows epidermal cornification but impairs skin barrier formation
J Invest Dermatol 138, 1268-1278, 2018. (Epub 2018 Jan 6)

Vandenabeele, P, Declercq, W, Roelandt, R, Vanden Berghe, T.
MLKL Reveals Its Friendly Face: A Role in Nerve Regeneration
Mol Cell 72, 397-399, 2018. (Epub 2018 Nov 1)

Devos, M, Gilbert, B, Denecker, G, Leurs, K, Mc Guire, C, Lemeire, K, Hochepied, T, Vuylsteke, M, Lambert, J, Van Den Broecke, C, Libbrecht, L, Haigh, J, Berx, G, Lippens, S, Vandenabeele, P, Declercq, W.
Elevated DeltaNp63alpha levels facilitate epidermal and biliary oncogenic transformation
J Invest Dermatol 137, 494-505, 2017. (Epub 2016 Oct 7)

Kurdi, A, Cleenewerck, M, Vangestel, C, Lyssens, S, Declercq, W, Timmermans, JP, Stroobants, S, Augustyns, K, De Meyer, GRY, Van Der Veken, P, Martinet, W.
ATG4B inhibitors with a benzotropolone core structure block autophagy and augment efficiency of chemotherapy in mice
Biochem Pharmacol 138, 150-162, 2017. (Epub 2017 Jun 19)

Latil, M, Nassar, D, Beck, B, Boumahdi, S, Wang, L, Brisebarre, A, Dubois, C, Nkusi, E, Lenglez, S, Checinska, A, Vercauteren Drubbel, A, Devos, M, Declercq, W, Yi, R, Blanpain, C.
Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
Cell Stem Cell 20, 191-204, 2017. (Epub 2016 Nov 16)

Aaes, TL, Kaczmarek, A, Delvaeye, T, De Craene, B, De Koker, S, Heyndrickx, L, Delrue, I, Taminau, J, Wiernicki, B, De Groote, P, Garg, AD, Leybaert, L, Grooten, J, Bertrand, MJ, Agostinis, P, Berx, G, Declercq, W, Vandenabeele, P, Krysko, DV.
Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity
Cell Rep 15, 274-287, 2016. (Epub 2016 Mar 30)

Cleenewerck, M, Grootaert, MO, Gladysz, R, Adriaenssens, Y, Roelandt, R, Joossens, J, Lambeir, AM, De Meyer, GR, Declercq, W, Augustyns, K, Martinet, W, Van der Veken, P.
Inhibitor screening and enzymatic activity determination for autophagy target Atg4B using a gel electrophoresis-based assay
Eur J Med Chem 123, 631-638, 2016. (Epub 2016 Jul 31)

De Groote, P, Grootjans, S, Lippens, S, Eichperger, C, Leurs, K, Kahr, I, Tanghe, G, Bruggeman, I, De Schamphelaire, W, Urwyler, C, Vandenabeele, P, Haustraete, J, Declercq, W.
Generation of a new Gateway-compatible inducible lentiviral vector platform allowing easy derivation of co-transduced cells
Biotechniques 60, 252-259, 2016. (Epub 2016 May 1)

Panayotova-Dimitrova, D, Declercq, W.
Martin Leverkus, MD (1965-2016)
J Invest Dermatol 136, 891-892, 2016. (Epub 2016 May)

Lyrio, EC, Campos-Souza, IC, Correa, C, Lechuga, G, Vericimo, M, Castro, HC, Bourguignon, SC, Faria, SC, Ratcliffe, N, Declercq, W, Santos, DO.
Interaction of Mycobacterium leprae with the HaCaT human keratinocyte cell line: New frontiers in the cellular immunology of leprosy
Exp Dermatol 24, 536-542, 2015. (Epub 2015 Apr 1)

Vorhagen, S, Jackow, J, Mohor, SG, Tanghe, G, Tanrikulu, L, Skazik-Vogt, C, Tellkamp, F.
Lineage tracing mediated by Cre-recombinase activity
J Invest Dermatol 135, e28, 2015. (Epub 2014 Dec 12)

De Groote, P, Tran, HT, Fransen, M, Tanghe, G, Urwyler, C, De Craene, B, Leurs, K, Gilbert, B, Van Imschoot, G, De Rycke, R, Guerin, CJ, Holland, P, Berx, G, Vandenabeele, P, Lippens, S, Vleminckx, K, Declercq, W.
A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes
Cell Death Differ 22, 1012-1024, 2014. (Epub 2014 Nov 28)

Dondelinger, Y, Declercq, W, Montessuit, S, Roelandt, R, Goncalves, A, Bruggeman, I, Hulpiau, P, Weber, K, Sehon, CA, Marquis, RW, Bertin, J, Gough, PJ, Savvides, S, Martinou, JC, Bertrand, MJ, Vandenabeele, P.
MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates
Cell Rep 7, 971981, 2014. (Epub 2014 May 7)

Kubica, M, Hildebrand, F, Brinkman, BM, Goossens, D, Del Favero, J, Vercammen, K, Cornelis, P, Schroder, JM, Vandenabeele, P, Raes, J, Declercq, W.
The skin microbiome of caspase-14 deficient mice shows mild dysbiosis
Exp Dermatol 23, 561-567, 2014. (Epub 2014 May 26)

Quimbaya, M, Raspe, E, Denecker, G, De Craene, B, Roelandt, R, Declercq, W, Sagaert, X, De Veylder, L, Berx, G.
Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability
Neoplasia 16, 694-709, 2014. (Epub 2014 Sep)

Takahashi, N, Vereecke, L, Bertrand, MJ, Duprez, L, Berger, SB, Divert, T, Goncalves, A, Sze, M, Gilbert, B, Kourula, S, Goossens, V, Lefebvre, S, Gunther, C, Becker, C, Bertin, J, Gough, PJ, Declercq, W, van Loo, G, Vandenabeele, P.
RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis
Nature 513, 95-99, 2014. (Epub 2014 Sep 4)

Vanden Berghe, T, Demon, D, Bogaert, P, Vandendriessche, B, Goethals, A, Depuydt, B, Vuylsteke, M, Roelandt, R, Van Wonterghem, E, Vandenbroecke, J, Choi, SM, Meyer, E, Krautwald, S, Declercq, W, Takahashi, N, Cauwels, A, Vandenabeele, P.
Simultaneous targeting of Interleukin-1 and -18 is required for protection against inflammatory and septic shock
Am J Respir Crit Care Med 189, 282-291, 2014. (Epub 2014 Jan 23)

Beck, IM, Drebert, ZJ, Hoya-Arias, R, Bahar, AA, Devos, M, Clarisse, D, Desmet, S, Bougarne, N, Ruttens, B, Gossye, V, Denecker, G, Lievens, S, Bracke, M, Tavernier, J, Declercq, W, Gevaert, K, Vanden Berghe, W, Haegeman, G, De Bosscher, K.
Compound A, a selective glucocorticoid receptor modulator, enhances heat shock protein hsp70 gene promoter activation
PLoS One 8, e69115, 2013. (Epub 2013 Jul 30)

Bisteau, X, Paternot, S, Colleoni, B, Ecker, K, Coulonval, K, De Groote, P, Declercq, W, Hengst, L, Roger, PP.
CDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction point
PLoS Genet 9, e1003546, 2013. (Epub 2013 May 30)

Declercq, W.
Caspase-14
In Handbook of Proteolytic Enzymes. (Rawlings, N.D. & Salvesen, G.S., eds.), Oxford, Academic Press, pp. 2280-2285, 2013. (Epub 2013 Jan)

Devos, M, De Groote, P, Gilbert, B, Bruggeman, I, Leurs, K, Lippens, S, Vandenabeele, P, Declercq, W.
Caspase-14 overexpression in hairless mice is not involved in utricle formation
Exp Dermatol 22, 484-486, 2013. (Epub 2013 Jul)

Eckhart, L, Lippens, S, Tschachler, E, Declercq, W.
Cell death by cornification
Biochim Biophys Acta - Mol Cell Res 1833, 3471-3480, 2013. (Epub 2013 Jun 20)

Hoste, E, Denecker, G, Gilbert, B, Van Nieuwerburgh, F, van der Fits, L, Asselbergh, B, De Rycke, R, Hachem, JP, Deforce, D, Prens, EP, Vandenabeele, P, Declercq, W.
Caspase-14-deficient mice are more prone to the development of parakeratosis
J Invest Dermatol 133, 742-750, 2013. (Epub 2012 Sep 27)

Devos, M, Prawitt, J, Staumont-Salle, D, Hoste, E, Fleury, S, Bouchaert, E, Gilbert, B, Lippens, S, Vandenabeele, P, Dombrowicz, D, Declercq, W.
Filaggrin degradation by Caspase-14 is required for UVB photoprotection but does not influence allergic sensitization in a mouse model of atopic dermatitis
J Invest Dermatol 132, 2857-2860, 2012. (Epub 2012 Aug 30)

Takahashi, N, Duprez, L, Grootjans, S, Cauwels, A, Nerinckx, W, Duhadaway, JB, Goossens, V, Roelandt, R, Van Hauwermeiren, F, Libert, C, Declercq, W, Callewaert, N, Prendergast, GC, Degterev, A, Yuan, J, Vandenabeele, P.
Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models
Cell Death Dis 3, e437, 2012. (Epub 2012 Nov 29)

Bertrand, MJ, Lippens, S, Staes, A, Gilbert, B, Roelandt, R, De Medts, J, Gevaert, K, Declercq, W, Vandenabeele, P.
cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to Receptor Interacting Protein Kinases 1 to 4 (RIP1-4)
PLoS One 6, e22356, 2011. (Epub 2011 Sep 22)

Brinkman, BM, Hildebrand, F, Kubica, M, Goosens, D, Del Favero, J, Declercq, W, Raes, J, Vandenabeele, P.
Caspase deficiency alters the murine gut microbiome
Cell Death Dis 2, e220, 2011. (Epub 2011 Oct 20)

Declercq, W, Agostinis, P, Vandenabeele, P.
18th Euroconference on Apoptosis in Ghent, Belgium, 1-4 September 2010
Cell Death Differ 18, 1540-1542, 2011. (Epub 2011 Jun 3)

Declercq, W, Takahashi, N, Vandenabeele, P.
Dual face apoptotic machinery: from initiator of apoptosis to guardian of necroptosis
Immunity 35, 493-495, 2011. (Epub 2011 Oct 28)

Duprez, L, Takahashi, N, Van Hauwermeiren, F, Vandendriessche, B, Goossens, V, Vanden Berghe, T, Declercq, W, Libert, C, Cauwels, A, Vandenabeele, P.
RIP Kinase-dependent necroptosis drives lethal systemic inflammatory response syndrome
Immunity 35, 908-918, 2011. (Epub 2011 Dec 23)

Hoste, E, Kemperman, P, Devos, M, Denecker, G, Kezic, S, Yau, N, Gilbert, B, Lippens, S, De Groote, P, Roelandt, R, Van Damme, P, Gevaert, K, Presland, RB, Takahara, H, Puppels, G, Caspers, P, Vandenabeele, P, Declercq, W.
Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin
J Invest Dermatol 131, 2233-2241, 2011. (Epub 2011 Jun 9)

Kantyka, T, Fischer, J, Wu, Z, Declercq, W, Reiss, K, Schroder, JM, Meyer-Hoffert, U.
Inhibition of Kallikrein-related peptidases by the serine protease inhibitor of Kazal-type 6
Peptides 32, 1187-1192, 2011. (Epub 2011 Mar 22)

Lippens, S, Hoste, E, Vandenabeele, P, Declercq, W.
Cell death in the skin
In Apoptosis: Physiology and pathology. (Reed, JC, Green, DR, eds.), Cambridge, Cambridge University Press, pp. 323-332, 2011. (Epub 2011)

Lippens, S, Lefebvre, S, Gilbert, B, Sze, M, Devos, M, Verhelst, K, Vereecke, L, Mc Guire, C, Guerin, C, Vandenabeele, P, Pasparakis, M, Mikkola, ML, Beyaert, R, Declercq, W, van Loo, G.
Keratinocyte-specific ablation of the NF-?B regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis
Cell Death Differ 18, 1845-1853, 2011. (Epub 2011 May 13)

Vanbokhoven, H, Melino, G, Candi, E, Declercq, W.
p63, a story of mice and men
J Invest Dermatol 131, 1196-1207, 2011. (Epub 2011 Apr 7)

Declercq, W.
Caspases in epidermal differentiation and cornification
Exp Dermatol 19, 938-940, 2010. (Epub ---)

Vandenabeele, P, Declercq, W, Van Herreweghe, F, Vanden Berghe, T.
The role of the kinases RIP1 and RIP3 in TNF-induced necrosis
Sci Signal 3, re4, 2010. (Epub 2010 Mar 30)

Vanden Berghe, T, Vanlangenakker, N, Parthoens, E, Deckers, W, Devos, M, Festjens, N, Guerin, CJ, Brunk, U, Declercq, W, Vandenabeele, P.
Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features
Cell Death Differ 17, 922-930, 2010. (Epub 2009 Dec 11)

Van Herreweghe, F, Festjens, N, Declercq, W, Vandenabeele, P.
Tumor necrosis factor-mediated cell death: to break or to burst, that's the question
Cell Mol Life Sci 67, 1567-1579, 2010. (Epub 2010 Mar 4)

Wirawan, E, Vande Walle, L, Kersse, K, Cornelis, S, Claerhout, S, Vanoverberghe, I, Roelandt, R, De Rycke, R, Verspurten, J, Declercq, W, Agostinis, P, Vanden Berghe, T, Lippens, S, Vandenabeele, P.
Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria
Cell Death Dis 1, e18, 2010. (Epub 2010 Jan 21)

Declercq, W, Vanden Berghe, T, Vandenabeele, P.
RIP kinases at the crossroads of cell death and survival
Cell 138, 229-232, 2009. (Epub 2009 Jul)

Declercq, W, Van Herreweghe, F, Vanden Berghe, T, Vandenabeele, P.
Death receptor-induced necroptosis
In Encyclopedia of Life Sciences. Chichester, Wiley & Sons, DOI: 10.1002/9780470015902.a0021566, 2009. (Epub 2009 Dec)

Demon, D, Van Damme, P, Vanden Berghe, T, Deceuninck, A, Van Durme, J, Verspurten, J, Helsens, K, Impens, F, Wejda, M, Schymkowitz, J, Rousseau, F, Madder, A, Vandekerckhove, J, Declercq, W, Gevaert, K, Vandenabeele, P.
Proteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificity
Mol Cell Proteomics 8, 2700-2714, 2009. (Epub 2009 Sep 16)

Demon, D, Van Damme, P, Vanden Berghe, T, Vandekerckhove, J, Declercq, W, Gevaert, K, Vandenabeele, P.
Caspase substrates: easily caught in deep waters?
Trends Biotechnol 27, 680-688, 2009. (Epub 2009 Oct 28)

Lippens, S, Hoste, E, Vandenabeele, P, Agostinis, P, Declercq, W.
Cell death in the skin
Apoptosis 14, 549-569, 2009. (Epub 2009 Feb 17)

Ovaere, P, Lippens, S, Vandenabeele, P, Declercq, W.
The emerging roles of serine protease cascades in the epidermis
Trends Biochem Sci 34, 453-463, 2009. (Epub 2009 Aug 31)

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