» Home » Research 
Print this pageEmail this page URLConvert this page to PDF

Publications from this research unit

This page shows only publications with IRC as the affiliation of at least one author.
Publications by IRC members mentioning other affiliations are not in our database. Sorry.
See "Extra muros" papers of the units.

For copyright reasons, PDF-versions of our publications are available on the intranet only (login required  ). If you would like to receive a reprint of an IRC paper, please copy/paste the reference in the
reprint request form 


Aegerter, H, Smole, U, Heyndrickx, I, Verstraete, K, Savvides, SN, Hammad, H, Lambrecht, BN.
Charcot-Leyden crystals and other protein crystals driving type 2 immunity and allergy
Curr Opin Immunol 72, 72-78, 2021. (Epub 2021 Apr 16)

Aguilera-Lizarraga, J, Florens, MV, Viola, MF, Jain, P, Decraecker, L, Appeltans, I, Cuende-Estevez, M, Fabre, N, Van Beek, K, Perna, E, Balemans, D, Stakenborg, N, Theofanous, S, Bosmans, G, Mondelaers, SU, Matteoli, G, Ibiza Martinez, S, Lopez-Lopez, C, Jaramillo-Polanco, J, et al..
Local immune response to food antigens drives meal-induced abdominal pain
Nature 590, 151-156, 2021. (Epub 2021 Jan 13)

Almeida, L, Dhillon-LaBrooy, A, Castro, CN, Adossa, N, Carriche, GM, Guderian, M, Lippens, S, Dennerlein, S, Hesse, C, Lambrecht, BN, Berod, L, Schauser, L, Blazar, BR, Kalesse, M, Muller, R, Moita, LF, Sparwasser, T.
Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis
Immunity 54, 68-83, 2021. (Epub 2020 Nov 24)

Backers, L, Parton, B, De Bruyne, M, Tavernier, SJ, Van Den Bogaert, K, Lambrecht, BN, Haerynck, F, Claes, KBM.
Missing heritability in Bloom syndrome: First report of a deep intronic variant leading to pseudo-exon activation in the BLM gene
Clin Genet 99, 292-297, 2021. (Epub 2020 Oct 9)

Baptista, AP, Gerner, MY.
Lymphoid stromal cells proGrem dendritic cell homeostasis
Nat Immunol 22, 541-543, 2021. (Epub 2021 Apr 26)

Bosteels, C, Fierens, K, De Prijck, S, Van Moorleghem, J, Vanheerswynghels, M, De Wolf, C, Chalon, A, Collignon, C, Hammad, H, Didierlaurent, AM, Lambrecht, BN.
CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Immunity by the Human Vaccine Adjuvant System AS01
Front Immunol 11, 606805, 2021. (Epub 2021 Jan 14)

Brightling, C, Kulkarni, S, Lambrecht, BN, Sandham, D, Weiss, M, Altman, P.
The pharmacology of the prostaglandin D2 receptor 2 (DP2) receptor antagonist, fevipiprant
Pulm Pharmacol Ther 68, 102030, 2021. (Epub 2021 Apr 4)

Cloots, E, Debeuf, N, Deswarte, K, Fayazpour, F, Vanheerswynghels, M, De Wolf, C, Van De Velde, E, Hammad, H, Lambrecht, BN, Eyckerman, S, Janssens, S.
IRE1beta does not affect mucus secretion during allergic asthma development in a house dust mite murine model
Allergy , in press, 2021. (Epub 2021 Aug 12)

de Reuver, R, Dierick, E, Wiernicki, B, Staes, K, Seys, L, De Meester, E, Muyldermans, T, Botzki, A, Lambrecht, BN, Van Nieuwerburgh, F, Vandenabeele, P, Maelfait, J.
ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation
Cell Rep 36, 109500, 2021. (Epub 2021 Aug 10)

De Vrieze, J, Baptista, AP, Nuhn, L, Van Herck, S, Deswarte, K, Yu, HJ, Lambrecht, BN, De Geest, BG.
Lipid Nature and Alkyl Length Influence Lymph Node Accumulation of Lipid-Polyethylene Glycol Amphiphiles
Advanced Therapeutics , in press, 2021. (Epub 2021 Jul 26)

Dhont, S, Derom, E, Van Braeckel, E, Depuydt, P, Lambrecht, BN.
Conceptions of the pathophysiology of happy hypoxemia in COVID-19
Respir Res 22, 12, 2021. (Epub 2021 Jan 8)

Gola, A, Dorrington, MG, Speranza, E, Sala, C, Shih, RM, Radtke, AJ, Wong, HS, Baptista, AP, Hernandez, JM, Castellani, G, Fraser, IDC, Germain, RN.
Commensal-driven immune zonation of the liver promotes host defence
Nature 589, 131-136, 2021. (Epub 2020 Nov 25)

Hammad, H, Lambrecht, BN.
The basic immunology of asthma
Cell 184, 1469-1485, 2021. (Epub 2021 Mar 18)

Huppertsberg, A, Kaps, L, Zhong, Z, Schmitt, S, Stickdorn, J, Deswarte, K, Combes, F, Czysch, C, De Vrieze, J, Kasmi, S, Choteschovsky, N, Klefenz, A, Medina-Montano, C, Winterwerber, P, Chen, C, Bros, M, Lienenklaus, S, Sanders, NN, Koynov, K, et al..
Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-like Receptor 7/8 Agonistic Immune Modulators
J Am Chem Soc 143, 9872-9883, 2021. (Epub 2021 Jun 24)

Jangra, S, De Vrieze, J, Choi, A, Rathnasinghe, R, Laghlali, G, Uvyn, A, Van Herck, S, Nuhn, L, Deswarte, K, Zhong, Z, Sanders, N, Lienenklaus, S, David, S, Strohmeier, S, Amanat, F, Krammer, F, Hammad, H, Lambrecht, BN, Coughlan, L, et al..
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine
Angew Chem Int Ed Engl 60, 9467-9473, 2021. (Epub 2021 Jan 19)

Meyts, I, Bucciol, G, Quinti, I, Neven, B, Fischer, A, Seoane, E, Lopez-Granados, E, Gianelli, C, Robles-Marhuenda, A, Jeandel, PY, Paillard, C, Sankaran, VG, Demirdag, YY, et al, Bosteels, C, Lambrecht, BN, et al..
Coronavirus Disease 2019 in patients with inborn errors of immunity: an international study
J Allergy Clin Immunol 147, 520-531, 2021. (Epub 2020 Sep 24)

Naesens, L, Smet, J, Tavernier, SJ, Schelstraete, P, Hoste, L, Lambrecht, S, Verhelst, H, van der Werff Ten Bosch, J, Ferster, A, Blumental, S, Hilbert, P, Kerre, T, Vande Walle, J, Licht, C, Roumenina, LT, Stordeur, P, Haerynck, F.
Plasma C3d levels as a diagnostic marker for complete complement factor I deficiency
J Allergy Clin Immunol 147, 749-753, 2021. (Epub 2020 Aug 24)

Oikonomou, N, Schuijs, MJ, Chatzigiagkos, A, Androulidaki, A, Aidinis, V, Hammad, H, Lambrecht, BN, Pasparakis, M.
Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation
Mucosal Immunol , in press, 2021. (Epub 2021 May 27)

Vanderkerken, M, Baptista, AP, De Giovanni, M, Fukuyama, S, Browaeys, R, Scott, CL, Norris, PS, Eberl, G, Di Santo, JP, Vivier, E, Saeys, Y, Hammad, H, Cyster, JG, Ware, CF, Tumanov, AV, De Trez, C, Lambrecht, BN.
ILC3s control splenic cDC homeostasis via lymphotoxin signaling
J Exp Med 218, e20190835, 2021. (Epub 2021 Mar 16)

Van Lysebetten, D, Malfanti, A, Deswarte, K, Koynov, K, Golba, B, Ye, T, Zhong, Z, Kasmi, S, Lamoot, A, Chen, Y, Van Herck, S, Lambrecht, BN, Sanders, NN, Lienenklaus, S, David, SA, Vicent, MJ, De Koker, S, De Geest, BG.
Lipid-Polyglutamate Nanoparticle Vaccine Platform
ACS Appl Mater Interfaces 13, 6011-6022, 2021. (Epub 2021 Jan 28)

Vidal-Quist, JC, Vidal, C, Escolar, F, Lambrecht, BN, Rombauts, S, Hernandez-Crespo, P.
RNA viruses in the house dust mite Dermatophagoides pteronyssinus, detection in environmental samples and in commercial allergen extracts used for in vivo diagnosis
Allergy , in press, 2021. (Epub 2021 Apr 29)

WHO REACT Working Group, Shankar-Hari, M, Vale, CL, Godolphin, PJ, Fisher, D, Higgins, JPT, Spiga, F, Savovic, J, Tierney, J, Baron, G, Benbenishty, JS, Berry, LR, Broman, N, Cavalcanti, AB, Colman, R, De Buyser, SL, Derde, LPG, Domingo, P, Omar, SF, et al..
Association Between Administration of IL-6 Antagonists and Mortality Among Patients Hospitalized for COVID-19: A Meta-analysis
JAMA 326, 499-518, 2021. (Epub 2021 Aug 10)

Bachert, C, Marple, B, Schlosser, RJ, Hopkins, C, Schleimer, RP, Lambrecht, BN, Broker, BM, Laidlaw, T, Song, WJ.
Adult chronic rhinosinusitis
Nat Rev Dis Primers 6, 86, 2020. (Epub 2020 Oct 29)

Beziat, V, Tavernier, SJ, Chen, YH, Ma, CS, Materna, M, Laurence, A, Staal, J, Aschenbrenner, D, Roels, L, Worley, L, Claes, K, Gartner, L, Kohn, LA, De Bruyne, M, Schmitz-Abe, K, Charbonnier, LM, Keles, S, Nammour, J, Vladikine, N, et al..
Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome
J Exp Med 217, e20191804, 2020. (Epub 2020 Mar 24)

Bogaert, DJ, Laureys, G, Naesens, L, Mazure, D, De Bruyne, M, Hsu, AP, Bordon, V, Wouters, E, Tavernier, SJ, Lambrecht, BN, De Baere, E, Haerynck, F, Kerre, T.
GATA2 deficiency and haematopoietic stem cell transplantation: challenges for the clinical practitioner
Br J Haematol 188, 768-773, 2020. (Epub 2019 Nov 11)

Bosteels, C, Maes, B, Van Damme, K, De Leeuw, E, Declercq, J, Delporte, A, Demeyere, B, Vermeersch, S, Vuylsteke, M, Willaert, J, Bolle, L, Vanbiervliet, Y, Decuypere, J, Libeer, F, Vandecasteele, S, Peene, I, Lambrecht, B.
Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial
Trials 21, 491, 2020. (Epub 2020 Jun 5)

Bosteels, C, Neyt, K, Vanheerswynghels, M, van Helden, MJ, Sichien, D, Debeuf, N, De Prijck, S, Bosteels, V, Vandamme, N, Martens, L, Saeys, Y, Louagie, E, Lesage, M, Williams, DL, Tang, SC, Mayer, JU, Ronchese, F, Scott, CL, Hammad, H, et al..
Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection
Immunity 52, 1039-1056, 2020. (Epub 2020 May 4)

Declercq, J, Bosteels, C, Van Damme, K, De Leeuw, E, Maes, B, Vandecauter, A, Vermeersch, S, Delporte, A, Demeyere, B, Vuylsteke, M, Lalla, M, Smart, T, Detalle, L, Bouw, R, Streffer, J, Degeeter, T, Vergotte, M, Guisez, T, Van Braeckel, E, et al..
Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV): A structured summary of a study protocol for a randomised controlled trial
Trials 21, 934, 2020. (Epub 2020 Nov 19)

Del Valle, JR, Betts, BC, Yu, XZ, Janssens, S, Lambrecht, BN, Simon, MC, Hu, CA.
Clarifying the translational potential of B-I09
Nat Chem Biol 16, 1152, 2020. (Epub 2020 Oct 16)

Devos, T, Geukens, T, Schauwvlieghe, A, Arien, KK, Barbezange, C, Cleeren, M, Compernolle, V, Dauby, N, Desmecht, D, Grimaldi, D, Lambrecht, BN, Luyten, A, Maes, P, Moutschen, M, Romano, M, Seyler, L, Nevessignsky, MT, Vandenberghe, K, van Griensven, J, et al..
A randomized, multicentre, open-label phase II proof-of-concept trial investigating the clinical efficacy and safety of the addition of convalescent plasma to the standard of care in patients hospitalized with COVID-19: the Donated Antibodies Working against nCoV (DAWn-Plasma) trial
Trials 21, 981, 2020. (Epub 2020 Nov 27)

Dhont, S, Derom, E, Van Braeckel, E, Depuydt, P, Lambrecht, BN.
The pathophysiology of 'happy' hypoxemia in COVID-19
Respir Res 21, 198, 2020. (Epub 2020 JUl 28)

Gevaert, E, Delemarre, T, De Volder, J, Zhang, N, Holtappels, G, De Ruyck, N, Persson, E, Heyndrickx, I, Verstraete, K, Aegerter, H, Nauwynck, H, Savvides, SN, Lambrecht, BN, Bachert, C.
Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis
J Allergy Clin Immunol 145, 427-430, 2020. (Epub 2019 Sep 4)

Hammad, H, Lambrecht, BN.
Rbm7 in Structural Cells: A NEAT Way to Control Fibrosis
Immunity 52, 429-431, 2020. (Epub 2020 Mar 17)

Hammad, H, Lambrecht, BN.
Wnt and Hippo pathways in regulatory T cells: a NOTCH above in asthma
Nat Immunol 21, 13131314, 2020. (Epub 2020 Sep 23)

Jangra, S, De Vrieze, J, Choi, A, Rathnasinghe, R, Laghlali, G, Uvyn, A, Van Herck, S, Nuhn, L, Deswarte, K, Zhong, Z, Sanders, N, Lienenklaus, S, David, S, Strohmeier, S, Amanat, F, Krammer, F, Hammad, H, Lambrecht, BN, Coughlan, L, et al..
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine
bioRxiv , , 2020. (Epub 2020 Oct 23)

Kerr, SC, Gonzalez, JR, Schanin, J, Peters, MC, Lambrecht, BN, Brock, EC, Charbit, A, Ansel, KM, Youngblood, BA, Fahy, JV.
An Anti-Siglec-8 Antibody Depletes Sputum Eosinophils from Asthmatic Subjects and Inhibits Lung Mast Cells
Clin Exp Allergy 50, 904-914, 2020. (Epub 2020 Jun 15)

Li, Z, Oh, H, Cung, M, Marquez, SJ, Sun, J, Hammad, H, Janssens, S, Pouliot, P, Lambrecht, BN, Yang, YS, Shim, JH, Greenblatt, MB.
TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization
Biochem Biophys Res Commun 531, 497-502, 2020. (Epub 2020 Aug 14)

Maes, B, Bosteels, C, De Leeuw, E, Declercq, J, Van Damme, K, Delporte, A, Demeyere, B, Vermeersch, S, Vuylsteke, M, Willaert, J, Bolle, L, Vanbiervliet, Y, Decuypere, J, Libeer, F, Vandecasteele, S, Peene, I, Lambrecht, B.
Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID): A structured summary of a study protocol for a randomised controlled trial
Trials 21, 468, 2020. (Epub 2020 Jun 3)

Naessens, T, Morias, Y, Hamrud, E, Gehrmann, U, Budida, R, Mattsson, J, Baker, T, Skogberg, G, Israelsson, E, Thorn, K, Schuijs, MJ, Angermann, B, Melville, F, Staples, KJ, Cunoosamy, DM, Lambrecht, BN.
Human Lung Conventional Dendritic Cells Orchestrate Lymphoid Neogenesis During COPD
Am J Respir Crit Care Med 202, 535-548, 2020. (Epub 2020 Apr 7)

Osier, F, Ting, JPY, Fraser, J, Lambrecht, BN, Romano, M, Gazzinelli, RT, Bortoluci, KR, Zamboni, DS, Akbar, AN, Evans, J, Brown, DE, Patel, KD, Wu, Y, Perez, AB, Perez, O, Kamradt, T, Falk, C, Barda-Saad, M, Ariel, A, et al..
The global response to the COVID-19 pandemic: how have immunology societies contributed?
Nat Rev Immunol 20, 594-602, 2020. (Epub 2020 Sep 10)

Slowicka, K, Petta, I, Blancke, G, Hoste, E, Dumas, E, Sze, M, Vikkula, H, Radaelli, E, Haigh, J, Jonckheere, S, Taminau, J, Vandamme, N, Wullaert, A, Tulchinsky, E, Nittner, D, Van Vlierberghe, P, De Hertogh, G, Baldin, P, Etlioglu, E, et al. Berx, G, Vereecke, L, van Loo,G.
Zeb2 drives invasive and microbiota-dependent colon carcinoma
Nature Cancer 1, 620-634, 2020. (Epub 2020 Jun 15)

Trocha, KM, Kip, P, Tao, M, MacArthur, MR, Trevino-Villarreal, H, Longchamp, A, Toussaint, W, Lambrecht, BN, de Vries, MR, Quax, PHA, Mitchell, JR, Ozaki, CK.
Short-Term Preoperative Protein Restriction Attenuates Vein Graft Disease via Induction of Cystathionine Upsilon-Lyase
Cardiovasc Res 116, 416428, 2020. (Epub 2019 Mar 29)

Van Damme, KFA, Tavernier, S, Van Roy, N, De Leeuw, E, Declercq, J, Bosteels, C, Maes, B, De Bruyne, M, Bogaert, D, Bosteels, V, Hoste, L, Naesens, L, Maes, P, Grifoni, A, Weiskopf, D, Sette, A, Depuydt, P, Van Braeckel, E, Haerynck, F, et al..
Case Report: Convalescent Plasma, a Targeted Therapy for Patients with CVID and Severe COVID-19
Front Immunol 11, 596761, 2020. (Epub 2020 Nov 20)

Vanderkerken, M, Maes, B, Vandersarren, L, Toussaint, W, Deswarte, K, Vanheerswynghels, M, Pouliot, P, Martens, L, Van Gassen, S, Arthur, CM, Kirkling, ME, Reizis, B, Conrad, D, Stowell, S, Hammad, H, Lambrecht, BN.
TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells
Proc Natl Acad Sci U S A 117, 31331-31342, 2020. (Epub 2020 Nov 19)

Van Gorp, H, Huang, L, Saavedra, P, Vuylsteke, M, Asaoka, T, Prencipe, G, Insalaco, A, Ogunjimi, B, Jeyaratnam, J, Cataldo, I, Jacques, P, Vermaelen, K, Dullaers, M, Joos, R, Sabato, V, Stella, A, Frenkel, J, De Benedetti, F, Dehoorne, J, et al..
Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever
Ann Rheum Dis 79, 960-968, 2020. (Epub 2020 Apr 20)

Vlaminck, S, Acke, F, Prokopakis, E, Speleman, K, Kawauchi, H, van Cutsem, JC, Hellings, PW, Jorissen, M, Seys, S, Bachert, C, Zele, TV, Lambrecht, BN, Gevaert, P.
Surgery in Nasal Polyp Patients: Outcome After a Minimum Observation of 10 Years
Am J Rhinol Allergy in press, , 2020. (Epub 2020 Oct 5)

Vroman, H, van Uden, D, Bergen, IM, van Hulst, JAC, Lukkes, M, van Loo, G, Clausen, BE, Boon, L, Lambrecht, BN, Hammad, H, Hendriks, RW, Kool, M.
Tnfaip3 expression in pulmonary conventional type 1 Langerin-expressing dendritic cells regulates T helper 2-mediated airway inflammation in mice
Allergy 75, 2587-2598, 2020. (Epub 2020 Apr 23)

Wang, B, Van Herck, S, Chen, Y, Bai, X, Zhong, Z, Deswarte, K, Lambrecht, BN, Sanders, NN, Lienenklaus, S, Scheeren, HW, David, SA, Kiessling, F, Lammers, T, De Geest, BG, Shi, Y.
Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles
J Am Chem Soc 142, 12133-12139, 2020. (Epub 2020 Jun 11)

Ballegeer, M, Vandewalle, J, Eggermont, M, Van Isterdael, G, Dejager, L, De Bus, L, Decruyenaere, J, Vandenbroucke, RE, Libert, C.
Overexpression of Gilz Protects Mice Against Lethal Septic Peritonitis
Shock 52, 208-214, 2019. (Epub 2018 Aug 17)

Bonnardel, J, T'Jonck, W, Gaublomme, D, Browaeys, R, Scott, CL, Martens, L, Vanneste, B, De Prijck, S, Nedospasov, SA, Kremer, A, Van Hamme, E, Borghgraef, P, Toussaint, W, De Bleser, P, Mannaerts, I, Beschin, A, van Grunsven, LA, Lambrecht, BN, Taghon, T, et al..
Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche
Immunity 51, 638-654, 2019. (Epub 2019 Sep 24)

Back to previous page

Export in CSV

Page 1 of 7
<< 1 - 2 - 3 - 4 - 5 - 6 - 7 >>

To top

What do these icons mean?

pdf file (800 kb)