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Afonina, IS, Van Nuffel, E, Beyaert, R.
Immune responses and therapeutic options in psoriasis
Cell Mol Life Sci 78, 2709–2727, 2021. (Epub 2021 Jan 2)

Backers, L, Parton, B, De Bruyne, M, Tavernier, SJ, Van Den Bogaert, K, Lambrecht, BN, Haerynck, F, Claes, KBM.
Missing heritability in Bloom syndrome: First report of a deep intronic variant leading to pseudo-exon activation in the BLM gene
Clin Genet 99, 292-297, 2021. (Epub 2020 Oct 9)

Heine, H, Adanitsch, F, Peternelj, TT, Haegman, M, Kasper, C, Ittig, S, Beyaert, R, Jerala, R, Zamyatina, A.
Tailored Modulation of Cellular Pro-inflammatory Responses With Disaccharide Lipid A Mimetics
Front Immunol 12, 631797, 2021. (Epub 2021 Mar 18)

Klionsky, DJ, Abdel-Aziz, AK, Abdelfatah, S, Abdellatif, M, Abdoli, A, Abel, S, Abeliovich, H, Abildgaard, MH, Abudu, YP, Acevedo-Arozena, A, Adamopoulos, IE, Adeli, K, Adolph, TE, Adornetto, A, Aflaki, E, Agam, G, Agarwal, A, Aggarwal, BB, Agnello, M, et al..
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Autophagy 1, 1-382, 2021. (Epub 2021 Feb 8)

Meireson, A, Tavernier, SJ, Van Gassen, S, Sundahl, N, Demeyer, A, Spaas, M, Kruse, V, Ferdinande, L, Van Dorpe, J, Hennart, B, Allorge, D, Haerynck, F, Decaestecker, K, Rottey, S, Saeys, Y, Ost, P, Brochez, L.
Immune Monitoring in Melanoma and Urothelial Cancer Patients Treated with Anti-PD-1 Immunotherapy and SBRT Discloses Tumor Specific Immune Signatures
Cancers (Basel) 13, 2630, 2021. (Epub 2021 May 27)

Meyts, I, Bucciol, G, Quinti, I, Neven, B, Fischer, A, Seoane, E, Lopez-Granados, E, Gianelli, C, Robles-Marhuenda, A, Jeandel, PY, Paillard, C, Sankaran, VG, Demirdag, YY, et al, Bosteels, C, Lambrecht, BN, et al..
Coronavirus Disease 2019 in patients with inborn errors of immunity: an international study
J Allergy Clin Immunol 147, 520-531, 2021. (Epub 2020 Sep 24)

Percier, P, De Prins, S, Tima, G, Beyaert, R, Grooten, J, Romano, M, Denis, O.
Aspergillus fumigatus Recognition by Dendritic Cells Negatively Regulates Allergic Lung Inflammation Through a TLR2/MyD88 Pathway
Am J Respir Cell Mol Biol 64, 39-49, 2021. (Epub 2020 Sep 24)

Skordos, I, Demeyer, A, Beyaert, R.
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry
STAR Protoc 2, 100351, 2021. (Epub 2021 Feb 20)

Staal, J, Driege, Y, Haegman, M, Kreike, M, Iliaki, S, Vanneste, D, Lork, M, Afonina, IS, Braun, H, Beyaert, R.
Defining the combinatorial space of PKC::CARD-CC signal transduction nodes
FEBS J 288, 1630-1647, 2021. (Epub 2020 Aug 13)

Sun, X, He, X, Zhang, Y, Hosaka, K, Andersson, P, Wu, J, Wu, J, Jing, X, Du, Q, Hui, X, Ding, B, Guo, Z, Hong, A, Liu, X, Wang, Y, Ji, Q, Beyaert, R, Yang, Y, Li, Q, et al..
Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism
Gut , in press, 2021. (Epub 2021 Feb 10)

Vanderhaeghen, T, Beyaert, R, Libert, C.
Bidirectional Crosstalk Between Hypoxia Inducible Factors and Glucocorticoid Signalling in Health and Disease
Front Immunol 12, 684085, 2021. (Epub 2021 Jun 4)

Van Hove, I, Van Bergen, T, Etienne, I, Holgado, A, Afonina, IS, Beyaert, R, Feyen, JH, Hu, TT.
IL-33trap-mediated IL-33 neutralization does not exacerbate choroidal neovascularization, but fails to protect against retinal degeneration in a dry age-related macular degeneration model
Exp Eye Res 207, 108608, 2021. (Epub 2021 Apr 27)

Van Wyngene, L, Vanderhaeghen, T, Petta, I, Timmermans, S, Corbeels, K, Van der Schueren, B, Vandewalle, J, Van Looveren, K, Wallaeys, C, Eggermont, M, Dewaele, S, Catrysse, L, van Loo, G, Beyaert, R, Vangoitsenhoven, R, Nakayama, T, Tavernier, J, De Bosscher, K, Libert, C.
ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation
iScience 24, 102790, 2021. (Epub 2021 Jun 28)

Beziat, V, Tavernier, SJ, Chen, YH, Ma, CS, Materna, M, Laurence, A, Staal, J, Aschenbrenner, D, Roels, L, Worley, L, Claes, K, Gartner, L, Kohn, LA, De Bruyne, M, Schmitz-Abe, K, Charbonnier, LM, Keles, S, Nammour, J, Vladikine, N, et al..
Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome
J Exp Med 217, e20191804, 2020. (Epub 2020 Mar 24)

Bogaert, DJ, Laureys, G, Naesens, L, Mazure, D, De Bruyne, M, Hsu, AP, Bordon, V, Wouters, E, Tavernier, SJ, Lambrecht, BN, De Baere, E, Haerynck, F, Kerre, T.
GATA2 deficiency and haematopoietic stem cell transplantation: challenges for the clinical practitioner
Br J Haematol 188, 768-773, 2020. (Epub 2019 Nov 11)

Braun, H, Staal, J.
Stabilization of the TAK1 adaptor proteins TAB2 and TAB3 is critical for optimal NF-kappaB activation
FEBS J 287, 3161-3164, 2020. (Epub 2020 Jan 29)

Demeyer, A, Beyaert, R.
Fragility can be a good thing in cancer
Nat Immunol 21, 11-13, 2020. (Epub 2019 Dec 10)

Demeyer, A, Driege, Y, Skordos, I, Coudenys, J, Lemeire, K, Elewaut, D, Staal, J, Beyaert, R.
Long-Term MALT1 Inhibition in Adult Mice Without Severe Systemic Autoimmunity
iScience 23, 101557, 2020. (Epub 2020 Sep 12)

Holgado, A, Braun, H, Verstraete, K, Vanneste, D, Callewaert, N, Savvides, SN, Afonina, IS, Beyaert, R.
Single-Chain Soluble Receptor Fusion Proteins as Versatile Cytokine Inhibitors
Front Immunol 11, 1422, 2020. (Epub 2020 Jul 13)

Kim, S.W, Goossens, A, Libert, C, Van Immerseel, F, Staal, J, Beyaert, R.
Phytohormones: Multifunctional nutraceuticals against metabolic syndrome and comorbid diseases
Biochem Pharmacol 175, 113866, 2020. (Epub 2020 Feb 20)

Martens, A, Priem, D, Hoste, E, Vetters, J, Rennen, S, Catrysse, L, Voet, S, Deelen, L, Sze, M, Vikkula, H, Slowicka, K, Hochepied, T, Iliaki, K, Wullaert, A, Janssens, S, Lamkanfi, M, Beyaert, R, Armaka, M, Bertrand, MJM, et al..
Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities
Nat Immunol 21, 381-387, 2020. (Epub 2020 Mar 16)

Minina, EA, Staal, J, Alvarez, VE, Berges, JA, Berman-Frank, I, Beyaert, R, Bidle, KD, Bornancin, F, Casanova, M, Cazzulo, JJ, Choi, CJ, Coll, NS, Dixit, VM, Dolinar, M, Fasel, N, Funk, C, Gallois, P, Gevaert, K, Gutierrez-Beltran, E, et al..
Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases
Mol Cell 77, 927-929, 2020. (Epub 2020 Mar 5)

Souffriau, J, Timmermans, S, Vanderhaeghen, T, Wallaeys, C, Van Looveren, K, Aelbrecht, L, Dewaele, S, Vandewalle, J, et al., Eggermont, M, De Rycke, R, De Bruyne, M, Ballegeer, M, Vandevyver, S, Hochepied, T, Beyaert, R, Libert, C.
Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium
EMBO Mol Med , e11917, 2020. (Epub 2020 Sep 11)

Staal, J.
Fytohormonen : verschillende bioactieve moleculen die metabolisme en ontsteking beïnvloeden in de mens
Bloedvaten, Hart, Longen 25, 32 - 35, 2020. (Epub 2020)

Van Damme, KFA, Tavernier, S, Van Roy, N, De Leeuw, E, Declercq, J, Bosteels, C, Maes, B, De Bruyne, M, Bogaert, D, Bosteels, V, Hoste, L, Naesens, L, Maes, P, Grifoni, A, Weiskopf, D, Sette, A, Depuydt, P, Van Braeckel, E, Haerynck, F, et al..
Case Report: Convalescent Plasma, a Targeted Therapy for Patients with CVID and Severe COVID-19
Front Immunol 11, 596761, 2020. (Epub 2020 Nov 20)

Van der Jeught, K, Sun, Y, Fang, Y, Zhou, Z, Jiang, H, Yu, T, Yang, J, Kamocka, MM, So, KM, Li, Y, Eyvani, H, Sandusky, GE, Frieden, M, Braun, H, Beyaert, R, He, X, Zhang, X, Zhang, C, Paczesny, S, et al..
ST2 as checkpoint target for colorectal cancer immunotherapy
JCI Insight 5, 136073, 2020. (Epub 2020 May 7)

Vandewalle, J, Vanderhaeghen, T, Beyaert, R, Libert, C.
Taking the STING Out of Sepsis?
Cell Host Microbe 27, 491-493, 2020. (Epub 2020 Apr 8)

Van Dingenen, J, Pieters, L, Van Nuffel, E, Lefebvre, RA.
Hemin reduces postoperative ileus in a heme oxygenase 1-dependent manner while dimethyl fumarate does without heme oxygenase 1-induction
Neurogastroenterol Motil , e13624, 2020. (Epub 2019 May 23)

Van Nuffel, E, Staal, J, Baudelet, G, Haegman, M, Driege, Y, Hochepied, T, Afonina, IS, Beyaert, R.
MALT1 targeting suppresses CARD14-induced psoriatic dermatitis in mice
EMBO Rep 21, e49237, 2020. (Epub 2020 Apr 28)

Cochet, F, Facchini, FA, Zaffaroni, L, Billod, JM, Coelho, H, Holgado, A, Braun, H, Beyaert, R, Jerala, R, Jimenez-Barbero, J, Martin-Santamaria, S, Peri, F.
Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties
Sci Rep 9, 919, 2019. (Epub 2019 Jan 29)

Cossarizza, A, Chang, HD, Radbruch, A, Acs, A, Adam, D, Adam-Klages, S, Agace, WW, Aghaeepour, N, Akdis, M, Allez, M, Almeida, LN, Alvisi, G, Anderson, G, Andra, I, Annunziato, F, Anselmo, A, Bacher, P, Baldari, CT, Bari, S, et al..
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
Eur J Immunol 49, 1457-1973, 2019. (Epub 2019 Oct)

Demeyer, A, Skordos, I, Driege, Y, Kreike, M, Hochepied, T, Baens, M, Staal, J, Beyaert, R.
MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner
Front Immunol 10, 1898, 2019. (Epub 2019 Aug 14)

Demeyer, A, Van Nuffel, E, Baudelet, G, Driege, Y, Kreike, M, Muyllaert, D, Staal, J, Beyaert, R.
MALT1-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging
Front Immunol 10, 2330, 2019. (Epub 2019 Oct 1)

Dendoncker, K, Timmermans, S, Vandewalle, J, Eggermont, M, Lempiainen, J, Van Hamme, E, Dewaele, S, Vandevyver, S, Ballegeer, M, Souffriau, J, Van Wyngene, L, Van Looveren, K, Vanderhaeghen, T, Beyaert, R, De Bosscher, K, Palvimo, JJ, Van Montagu, M, Libert, C.
TNF-alpha inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile
Proc Natl Acad Sci U S A 116, 12942-12951, 2019. (Epub 2019 Jun 10)

Drutman, SB, Haerynck, F, Zhong, FL, Hum, D, Hernandez, NJ, Belkaya, S, Rapaport, F, de Jong, SJ, Creytens, D, Tavernier, SJ, Bonte, K, De Schepper, S, van der Werff Ten Bosch, J, Lorenzo-Diaz, L, Wullaert, A, Bossuyt, X, Orth, G, Bonagura, VR, Beziat, V, et al..
Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form of recurrent respiratory papillomatosis
Proc Natl Acad Sci U S A 116, 19055-19063, 2019. (Epub 2019 Sep 4)

Emmaneel, A, Bogaert, DJ, Van Gassen, S, Tavernier, SJ, Dullaers, M, Haerynck, F, Saeys, Y.
A Computational Pipeline for the Diagnosis of CVID Patients
Frontiers in Immunology 10, 2009, 2019. (Epub 2019 Aug 30)

Gilis, E, Gaublomme, D, Staal, J, Venken, K, Dhaenens, M, Lambrecht, S, Coudenys, J, Decruy, T, Schryvers, N, Driege, Y, Dumas, E, Demeyer, A, De Muynck, A, van Hengel, J, Van Hoorebeke, L, Deforce, D, Beyaert, R, Elewaut, D.
Deletion of Mucosa‐Associated Lymphoid Tissue Lymphoma Translocation Protein 1 in Mouse T Cells Protects Against Development of Autoimmune Arthritis but Leads to Spontaneous Osteoporosis
Arthritis Rheumatol 71, 2005-2015, 2019. (Epub 2019 Jul 1)

Holgado, A, Braun, H, Van Nuffel, E, Detry, S, Schuijs, MJ, Deswarte, K, Vergote, K, Haegman, M, Baudelet, G, Haustraete, J, Hammad, H, Lambrecht, BN, Savvides, SN, Afonina, IS, Beyaert, R.
IL-33trap is a novel IL-33 neutralizing biologic that inhibits allergic airway inflammation
J Allergy Clin Immunol 144, 204-215, 2019. (Epub 2019 Mar 12)

Lork, M, Staal, J, Beyaert, R.
Ubiquitination and phosphorylation of the CARD11-BCL10-MALT1 signalosome in T cells
Cell Immunol 340, 103877, 2019. (Epub 2018 Nov 9)

Pauwels, AM, Hartlova, A, Peltier, J, Driege, Y, Baudelet, G, Brodin, P, Trost, M, Beyaert, R, Hoffmann, E.
Spatiotemporal changes of the phagosomal proteome in dendritic cells in response to LPS stimulation
Mol Cell Proteomics 18, 909-922, 2019. (Epub 2019 Feb 26)

Staal, J, Alci, K, De Schamphelaire, W, Vanhoucke, M, Beyaert, R.
Engineering a minimal cloning vector from a pUC18 plasmid backbone with an extended multiple cloning site
Biotechniques 66, 254-259, 2019. (Epub 2019 May 24)

Tavernier, SJ, Athanasopoulos, V, Verloo, P, Behrens, G, Staal, J, Bogaert, DJ, Naesens, L, De Bruyne, M, Van Gassen, S, Parthoens, E, Ellyard, J, Cappello, J, Morris, LX, Van Gorp, H, Van Isterdael, G, Saeys, Y, Lamkanfi, M, Schelstraete, P, Dehoorne, J, et al..
A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation
Nat Commun 10, 4779, 2019. (Epub 2019 oct 21)

Adanitsch, F, Shi, J, Shao, F, Beyaert, R, Heine, H, Zamyatina, A.
Synthetic glycan-based TLR4 agonists targeting caspase-4/11 for the development of adjuvants and immunotherapeutics
Chem Sci 9, 3957-3963, 2018. (Epub 2018 Mar 15)

Andersson, P, Yang, Y, Hosaka, K, Zhang, Y, Fischer, C, Braun, H, Liu, S, Yu, G, Liu, S, Beyaert, R, Chang, M, Li, Q, Cao, Y.
Molecular mechanisms of IL-33-mediated stromal interactions in cancer metastasis
JCI Insight 3, e122375, 2018. (Epub 2018 Oct 18)

Ballegeer, M, Van Looveren, K, Timmermans, S, Eggermont, M, Vandevyver, S, Thery, F, Dendoncker, K, Souffriau, J, Vandewalle, J, Van Wyngene, L, De Rycke, R, Takahashi, N, Vandenabeele, P, Tuckermann, J, Reichardt, HM, Impens, F, Beyaert, R, De Bosscher, K, Vandenbroucke, RE, et al..
Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice
J Clin Invest 128, 3265-3279, 2018. (Epub 2018 May 10)

Beyaert, R, Libert, C.
How Good Roommates Can Protect against Microbial Sepsis
Cell Host Microbe 23, 283-285, 2018. (Epub 2018 Mar 14)

Borghi, A, Haegman, M, Fischer, R, Carpentier, I, Bertrand, MJM, Libert, C, Afonina, IS, Beyaert, R.
The E3 ubiquitin ligases HOIP and cIAP1 are recruited to the TNFR2 signaling complex and mediate TNFR2-induced canonical NF-kappaB signaling
Biochem Pharmacol 153, 292-298, 2018. (Epub 2018 Jan 26)

Borio, A, Holgado, A, Beyaert, R, Heine, H, Zamyatina, A.
Disaccharide-based Anionic Amphiphiles as Potent Inhibitors of LPS-induced Inflammation
ChemMedChem 13, 2317-2331, 2018. (Epub 2018 Oct 1)

Braun, H, Afonina, IS, Mueller, C, Beyaert, R.
Dichotomous function of IL-33 in health and disease: from biology to clinical implications
Biochem Pharmacol 148, 238-252, 2018. (Epub 2018 Jan 5)

Casillo, A, Ziaco, M, Lindner, B, Parrilli, E, Schwudke, D, Holgado, A, Beyaert, R, Lanzetta, R, Tutino, ML, Corsaro, MM.
Lipid A structural characterization from the LPS of the Siberian psychro-tolerant Psychrobacter arcticus 273-4 grown at low temperature
Extremophiles 22, 955-963, 2018. (Epub 2018 Aug 20)

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