• About IRC
  • Mission Statement
  • Historical Overview
  • Directors
    • Bart LAMBRECHT
    • Frans VAN ROY
    • Walter FIERS
  • IRC Calendar
  • More Events
    • IRC Events
    • IRC Calendar
    • IRC Symposia
    • Meetings and conferences
  • People
    • Personnel directory
    • By unit or function
  • Jobs & grant calls
  • Where to find us
  • Mobility
  • Contact us
  • Websites hosted by IRC
    • EIP team
  • Wireless Internet @ FSVM
• Research
  • Mission Statement
  • VIB Research groups
    • AFONINA, UGent
    • BERTRAND, UGent
    • BEYAERT, UGent
    • DECLERCQ, UGent
    • ELEWAUT, UGent
    • GUILLIAMS, UGent
    • HAMMAD, UGent
    • HOSTE, UGent
    • JANSSENS, UGent
    • KLEINEWIETFELD, UHasselt
    • LAMBRECHT, UGent
    • LAOUI, VUB
    • LAUKENS, UGent
    • LIBERT, UGent
    • MAELFAIT, UGent
    • RAVICHANDRAN, UGent
    • SAEYS, UGent
    • SAVVIDES, UGent
    • SCOTT, UGent
    • STAAL, UGent
    • VANDENABEELE, UGent
    • VANDEN BERGHE, UGent and UA
    • VANDENBROUCKE, UGent
    • VAN GINDERACHTER, VUB
    • VAN LOO, UGent
    • VEREECKE, UGent
    • WULLAERT, UGent
  • UGent Research groups
    • BERX, UGent
    • VERMEIRSSEN, UGent
    • VLEMINCKX, UGent
  • IRC Core Facilities
    • BCCM/GeneCorner
    • Transgenic Core Facility
    • VIB Bioimaging Core
    • VIB Flow Core
    • VIB Protein Core
  • Ethical committee
    • Ethical committee
    • House rules
    • FAQ
    • Submit application (Sharepoint)
  • Funding
  • Patents & Applications
  • PhD theses
  • Publications
    • All or selected
    • By research unit
  • Spin-off companies
    • ActoGeniX
    • Q-Biologicals
    • Oxyrane Belgium
• Education
  • PhD Theses
  • UGent Vakgroep WE14
  • BiochemBiotech@UGent
  • PhD Projects
  • Doctoral Schools
  • Ufora [UGent]

• Contact
  • How to contact us
  • Where to find us
• Sitemap
• Search
  • Site content
  • People

This page shows only publications with IRC as the affiliation of at least one author.
Publications by IRC members mentioning other affiliations are not in our database. Sorry.
See "Extra muros" papers of the units.

For copyright reasons, PDF-versions of our publications are available on the intranet only (login required  ). If you would like to receive a reprint of an IRC paper, please copy/paste the reference in the
reprint request form 

Bosteels, V, Marechal, S, De Nolf, C, Rennen, S, Maelfait, J, Tavernier, SJ, Vetters, J, Van De Velde, E, Fayazpour, F, Deswarte, K, Lamoot, A, Van Duyse, J, Martens, L, Bosteels, C, Roelandt, R, Emmaneel, A, Van Gassen, S, Boon, L, Van Isterdael, G, et al.. LXR signaling controls homeostatic dendritic cell maturation Sci Immunol 8, eadd3955, 2023. (Epub 2023 May 12)

Bosteels, C, Van Damme, KFA, De Leeuw, E, Declercq, J, Maes, B, Bosteels, V, Hoste, L, Naesens, L, Debeuf, N, Deckers, J, Cole, B, Pardons, M, Weiskopf, D, Sette, A, Weygaerde, YV, Malfait, T, Vandecasteele, SJ, Demedts, IK, Slabbynck, H, et al.. Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment Cell Rep Med 3, 100833, 2022. (Epub 2022 Nov 15)

Hoste, L, Roels, L, Naesens, L, Bosteels, V, Vanhee, S, Dupont, S, Bosteels, C, Browaeys, R, Vandamme, N, Verstaen, K, Roels, J, Van Damme, KFA, Maes, B, De Leeuw, E, Declercq, J, Aegerter, H, Seys, L, Smole, U, De Prijck, S, et al.. TIM3+ TRBV11-2 T cells and IFNgamma signature in patrolling monocytes and CD16+ NK cells delineate MIS-C J Exp Med 219, e20211381, 2022. (Epub 2021 Dec 16)

Maes, B, Smole, U, Vanderkerken, M, Deswarte, K, Van Moorleghem, J, Vergote, K, Vanheerswynghels, M, De Wolf, C, De Prijck, S, Debeuf, N, Pavie, B, Toussaint, W, Janssens, S, Savvides, S, Lambrecht, BN, Hammad, H. The STE20 kinase TAOK3 controls the development house dust mite-induced asthma in mice J Allergy Clin Immunol 149, 1413-1427, 2022. (Epub 2021 Sep 8)

Murgaski, A, Kiss, M, Van Damme, H, Kancheva, D, Vanmeerbeek, I, Keirsse, J, Hadadi, E, Brughmans, J, Arnouk, SM, Hamouda, AEI, Debraekeleer, A, Bosteels, V, Elkrim, Y, Boon, L, Hoves, S, Vandamme, N, Deschoemaeker, S, Janssens, S, Garg, AD, et al.. Efficacy of CD40 agonists is mediated by distinct cDC subsets and subverted by suppressive macrophages Cancer Res , in press, 2022. (Epub 2022 Aug 18)

Rufo, N, Korovesis, D, Van Eygen, S, Derua, R, Garg, AD, Finotello, F, Vara-Perez, M, Rozanc, J, Dewaele, M, de Witte, PA, Alexopoulos, LG, Janssens, S, Sinkkonen, L, Sauter, T, Verhelst, SHL, Agostinis, P. Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1alpha kinase inhibitor KIRA6 through HSP60 targeting Cell Death Differ 29, 230-245, 2022. (Epub 2021 Aug 27)

Catrysse, L, Maes, B, Mehrotra, P, Martens, A, Hoste, E, Martens, L, Maueroder, C, Remmerie, A, Bujko, A, Slowicka, K, Sze, M, Vikkula, H, Ghesquiere, B, Scott, CL, Saeys, Y, van de Sluis, B, Ravichandran, K, Janssens, S, van Loo, G. A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism Cell Rep 36, 109748, 2021. (Epub 2021 Sep 21)

Cloots, E, Debeuf, N, Deswarte, K, Fayazpour, F, Vanheerswynghels, M, De Wolf, C, Van De Velde, E, Hammad, H, Lambrecht, BN, Eyckerman, S, Janssens, S. IRE1beta does not affect mucus secretion during allergic asthma development in a house dust mite murine model Allergy 76, 3546-3549, 2021. (Epub 2021 Aug 12)

Cloots, E, Simpson, MS, De Nolf, C, Lencer, WI, Janssens, S, Grey, MJ. Evolution and function of the epithelial cell-specific ER stress sensor IRE1beta Mucosal Immunol 14, 1235–1246, 2021. (Epub 2021 Jun 1)

Declercq, J, Van Damme, KFA, De Leeuw, E, Maes, B, Bosteels, C, Tavernier, SJ, De Buyser, S, Colman, R, Hites, M, Verschelden, G, Fivez, T, Moerman, F, Demedts, IK, Dauby, N, De Schryver, N, Govaerts, E, Vandecasteele, SJ, Van Laethem, J, Anguille, S, et al.. Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID): a factorial, randomised, controlled trial Lancet Respir Med 9, 1427-1438, 2021. (Epub 2021 Oct 29)

Poncet, AF, Bosteels, V, Hoffmann, E, Chehade, S, Rennen, S, Huot, L, Peucelle, V, Marechal, S, Khalife, J, Blanchard, N, Janssens, S, Marion, S. The UPR sensor IRE1alpha promotes dendritic cell responses to control Toxoplasma gondii infection EMBO Rep 22, e49617, 2021. (Epub 2021 Feb 15)

van Anken, E, Bakunts, A, Hu, CA, Janssens, S, Sitia, R. Molecular Evaluation of Endoplasmic Reticulum Homeostasis Meets Humoral Immunity Trends Cell Biol 31, 529-541, 2021. (Epub 2021 Mar 5)

Bosteels, C, Neyt, K, Vanheerswynghels, M, van Helden, MJ, Sichien, D, Debeuf, N, De Prijck, S, Bosteels, V, Vandamme, N, Martens, L, Saeys, Y, Louagie, E, Lesage, M, Williams, DL, Tang, SC, Mayer, JU, Ronchese, F, Scott, CL, Hammad, H, et al.. Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection Immunity 52, 1039-1056, 2020. (Epub 2020 May 4)

Del Valle, JR, Betts, BC, Yu, XZ, Janssens, S, Lambrecht, BN, Simon, MC, Hu, CA. Clarifying the translational potential of B-I09 Nat Chem Biol 16, 1152, 2020. (Epub 2020 Oct 16)

Govindarajan, S, Verheugen, E, Venken, K, Gaublomme, D, Maelegheer, M, Cloots, E, Gysens, F, De Geest, BG, Cheng, TY, Moody, DB, Janssens, S, Drennan, M, Elewaut, D. ER stress in antigen-presenting cells promotes NKT cell activation through endogenous neutral lipids EMBO Rep , e48927, 2020. (Epub 2020 May 3)

Grey, MJ, Cloots, E, Simpson, MS, LeDuc, N, Serebrenik, YV, De Luca, H, De Sutter, D, Luong, P, Thiagarajah, JR, Paton, AW, Paton, JC, Seeliger, MA, Eyckerman, S, Janssens, S, Lencer, WI. IRE1beta negatively regulates IRE1alpha signaling in response to endoplasmic reticulum stress J Cell Biol 219, e201904048, 2020. (Epub 2020 Feb 3)

Li, Z, Oh, H, Cung, M, Marquez, SJ, Sun, J, Hammad, H, Janssens, S, Pouliot, P, Lambrecht, BN, Yang, YS, Shim, JH, Greenblatt, MB. TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization Biochem Biophys Res Commun 531, 497-502, 2020. (Epub 2020 Aug 14)

Martens, A, Priem, D, Hoste, E, Vetters, J, Rennen, S, Catrysse, L, Voet, S, Deelen, L, Sze, M, Vikkula, H, Slowicka, K, Hochepied, T, Iliaki, K, Wullaert, A, Janssens, S, Lamkanfi, M, Beyaert, R, Armaka, M, Bertrand, MJM, et al.. Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities Nat Immunol 21, 381-387, 2020. (Epub 2020 Mar 16)

Van Damme, KFA, Tavernier, S, Van Roy, N, De Leeuw, E, Declercq, J, Bosteels, C, Maes, B, De Bruyne, M, Bogaert, D, Bosteels, V, Hoste, L, Naesens, L, Maes, P, Grifoni, A, Weiskopf, D, Sette, A, Depuydt, P, Van Braeckel, E, Haerynck, F, et al.. Case Report: Convalescent Plasma, a Targeted Therapy for Patients with CVID and Severe COVID-19 Front Immunol 11, 596761, 2020. (Epub 2020 Nov 20)

Ydens, E, Amann, L, Asselbergh, B, Scott, CL, Martens, L, Sichien, D, Mossad, O, Blank, T, De Prijck, S, Low, D, Masuda, T, Saeys, Y, Timmerman, V, Stumm, R, Ginhoux, F, Prinz, M, Janssens, S, Guilliams, M. Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury Nat Neurosci 23, 676-689, 2020. (Epub 2020 Apr 13)

Debeuf, N, Zhakupova, A, Steiner, R, Van Gassen, S, Deswarte, K, Fayazpour, F, Van Moorleghem, J, Vergote, K, Pavie, B, Lemeire, K, Hammad, H, Hornemann, T, Janssens, S, Lambrecht, BN. The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice J Allergy Clin Immunol 144, 1648-1659, 2019. (Epub 2019 Jul 20)

Krols, M, Asselbergh, B, De Rycke, R, De Winter, V, Seyer, A, Muller, FJ, Kurth, I, Bultynck, G, Timmerman, V, Janssens, S. Sensory neuropathy-causing mutations in ATL3 affect ER-mitochondria contact sites and impair axonal mitochondrial distribution Hum Mol Genet 28, 615–627, 2019. (Epub 2018 Oct 18)

Mogilenko, DA, Haas, JT, L'Homme, L, Fleury, S, Quemener, S, Levavasseur, M, Becquart, C, Wartelle, J, et al., Tavernier, S, Berod, L, Longhi, MP, Paget, C, Janssens, S, et al., Dombrowicz, D. Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR Cell 4177, 1201-1216.e19, 2019. (Epub 2019 Apr 19)

Vetters, J, van Helden, MJ, Wahlen, S, Tavernier, SJ, Martens, A, Fayazpour, F, Vergote, K, Vanheerswynghels, M, Deswarte, K, Van Moorleghem, J, De Prijck, S, Takahashi, N, Vandenabeele, P, Boon, L, van Loo, G, Vivier, E, Lambrecht, BN, Janssens, S. The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF J Exp Med 216, 2010-2023, 2019. (Epub 2019 Jul 11)

D'Hondt, S, Guillemyn, B, Syx, D, Symoens, S, De Rycke, R, Vanhoutte, L, Toussaint, W, Lambrecht, BN, De Paepe, A, Keene, DR, Ishikawa, Y, Bachinger, HP, Janssens, S, Bertrand, MJM, Malfait, F. Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model Matrix Biol 70, 72-83, 2018. (Epub 2018 Mar 15)

Govindarajan, S, Gaublomme, D, Van der Cruyssen, R, Verheugen, E, Van Gassen, S, Saeys, Y, Tavernier, S, Iwawaki, T, Bloch, Y, Savvides, SN, Lambrecht, BN, Janssens, S, Elewaut, D, Drennan, MB. Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine kinase IRE1alpha Nat Commun 9, 5340, 2018. (Epub 2018 Dec 17)

Krols, M, Detry, S, Asselbergh, B, Almeida-Souza, L, Kremer, A, Lippens, S, De Rycke, R, De Winter, V, Muller, FJ, Kurth, I, McMahon, HT, Savvides, SN, Timmerman, V, Janssens, S. Sensory-Neuropathy-Causing Mutations in ATL3 Cause Aberrant ER Membrane Tethering Cell Rep 23, 2026-2038, 2018. (Epub 2018 May 15)

Osorio, F, Lambrecht, BN, Janssens, S. Antigen presentation unfolded: identifying convergence points between the UPR and antigen presentation pathways Curr Opin Immunol 52, 100-107, 2018. (Epub 2018 May 10)

Tavernier, SJ, Lambrecht, BN, Janssens, S. The Unfolded Protein Response in the Immune Cell Development: Putting the Caretaker in the Driving Seat Curr Top Microbiol Immunol 414, 45-72, 2018. (Epub 2017 Jul 13)

Hammad, H, Vanderkerken, M, Pouliot, P, Deswarte, K, Toussaint, W, Vergote, K, Vandersarren, L, Janssens, S, Ramou, I, Savvides, SN, Haigh, JJ, Hendriks, R, Kopf, M, Craessaerts, K, de Strooper, B, Kearney, JF, Conrad, DH, Lambrecht, BN. Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10 Nat Immunol 18, 313–320, 2017. (Epub 2017 Jan 9)

Kennedy, D, Mnich, K, Oommen, D, Chakravarthy, R, Almeida-Souza, L, Krols, M, Saveljeva, S, Doyle, K, Gupta, S, Timmerman, V, Janssens, S, Gorman, AM, Samali, A. HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis Cell Death Dis 8, e3026, 2017. (Epub 2017 Aug 31)

Klein Geltink, RI, O'Sullivan, D, Corrado, M, Bremser, A, Buck, MD, et al., Caputa, G, Kelly, B, Warthorst, U, Rensing-Ehl, A, Kyle, RL, Vandersarren, L, et al., Janssens, S, Lambrecht BN , et al., Curtis, JD, Patterson, AE, Lawless, S, Grzes, K, et al.. Mitochondrial Priming by CD28 Cell 171, 385-397, 2017. (Epub 2017 Sep 14)

Tavernier, SJ, Osorio, F, Vandersarren, L, Vetters, J, Vanlangenakker, N, Van Isterdael, G, Vergote, K, De Rycke, R, Parthoens, E, van de Laar, L, Iwawaki, T, Del Valle, JR, Hu, CCA, Lambrecht, BN, Janssens, S. Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival Nat Cell Biol 19, 698-710, 2017. (Epub 2017 May 1)

Tavernier, SJ, Vanlangenakker, N, Vetters, J, Carmeliet, P, Janssens, S, Lambrecht, BN. Opposing regulation and roles for PHD3 in lung dendritic cells and alveolar macrophages J Leukoc Biol 102, 1115-1126, 2017. (Epub 2017 Jul 17)

Vanacker, H, Vetters, J, Moudombi, L, Caux, C, Janssens, S, Michallet, MC. Emerging Role of the Unfolded Protein Response in Tumor Immunosurveillance Trends Cancer 3, 491-505, 2017. (Epub 2017 Jul)

Vandersarren, L, Bosteels, C, Vanheerswynghels, M, Moon, JJ, Easton, AJ, Van Isterdael, G, Janssens, S, Lambrecht, BN, van Helden, MJ. Epitope mapping and kinetics of CD4 T cell immunity to pneumonia virus of mice in the C57BL/6 strain Sci Rep 7, 3472, 2017. (Epub 2017 Jun 14)

Van Welden, S, De Vos, M, Wielockx, B, Tavernier, SJ, Dullaers, M, Neyt, S, Descamps, B, Devisscher, L, Devriese, S, Van den Bossche, L, Holvoet, T, Baeyens, A, Correale, C, D'Alessio, S, Vanhove, C, De Vos, F, Verhasselt, B, Breier, G, Lambrecht, BN, et al.. Haematopoietic prolyl hydroxylase-1 deficiency promotes M2 macrophage polarization and is both necessary and sufficient to protect against experimental colitis J Pathol 241, 547–558 , 2017. (Epub 2016 Dec 16)

Bouhy, D, Geuens, T, De Winter, V, Almeida-Souza, L, Katona, I, Weis, J, Hochepied, T, Goossens, S, Haigh, J, Janssens, S, Timmerman, V. Characterization of New Transgenic Mouse Models for Two Charcot-Marie-Tooth-Causing HspB1 Mutations using the Rosa26 Locus Journal of Neuromuscular Diseases 3, 183-200, 2016. (Epub 2016 May 27)

Debeuf, N, Haspeslagh, E, van Helden, M, Hammad, H, Lambrecht, BN. Mouse Models of Asthma Curr Protoc Mouse Biol 6, 169-184, 2016. (Epub 2016 Jun 1)

Krols, M, Bultynck, G, Janssens, S. ER-Mitochondria contact sites: A new regulator of cellular calcium flux comes into play J Cell Biol 214, 367-370, 2016. (Epub 2016 Aug 15)

Krols, M, van Isterdael, G, Asselbergh, B, Kremer, A, Lippens, S, Timmerman, V, Janssens, S. Mitochondria-associated membranes as hubs for neurodegeneration Acta Neuropathol 131, 505-523, 2016. (Epub 2016 Jan 7)

Thyrion, L, Raedt, R, Portelli, J, Van Loo, P, Wadman, WJ, Glorieux, G, Lambrecht, BN, Janssens, S, Vonck, K, Boon, P. Uric acid is released in the brain during seizure activity and increases severity of seizures in a mouse model for acute limbic seizures Exp Neurol 277, 244-251, 2016. (Epub 2016 Jan 8)

van de Laar, L, Guilliams, M, Tavernier, SJ. Isolation of Conventional Dendritic Cells from Mouse Lungs Methods Mol Biol 1423, 139-152, 2016. (Epub 2016 May 4)

Zhakupova, A, Debeuf, N, Krols, M, Toussaint, W, Vanhoutte, L, Alecu, I, Kutalik, Z, Vollenweider, P, Ernst, D, von Eckardstein, A, Lambrecht, BN, Janssens, S, Hornemann, T. ORMDL3 expression levels have no influence on the activity of serine palmitoyltransferase FASEB J 30, 4289-4300, 2016. (Epub 206 Sep 19)

Kremer, A, Lippens, S, Bartunkova, S, Asselbergh, B, Blanpain, C, Fendrych, M, Goossens, A, Holt, M, Janssens, S, Krols, M, Larsimont, JC, Mc Guire, C, Nowack, MK, Saelens, X, Schertel, A, Schepens, B, Slezak, M, Timmerman, V, Theunis, C, et al.. Developing 3D SEM in a broad biological context J Microsc 259, 80-96, 2015. (Epub 2015 Jan 26)

Ydens, E, Demon, D, Lornet, G, De Winter, V, Timmerman, V, Lamkanfi, M, Janssens, S. Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes J Neuroinflammation 12, 143, 2015. (Epub 2015 Aug 8)

Janssens, S, Pulendran, B, Lambrecht, BN. Emerging functions of the unfolded protein response in immunity Nat Immunol 15, 910-919, 2014. (Epub 2014 Sep 18)

Osorio, F, Tavernier, SJ, Hoffmann, E, Saeys, Y, Martens, L, Vetters, J, Delrue, I, De Rycke, R, Parthoens, E, Pouliot, P, Iwawaki, T, Janssens, S, Lambrecht, BN. The unfolded-protein-response sensor IRE-1alpha regulates the function of CD8alpha+ dendritic cells Nat Immunol 15, 248-257, 2014. (Epub 2014 Jan 19)

Vandewynckel, YP, Laukens, D, Bogaerts, E, Paridaens, A, Van den Bussche, A, Verhelst, X, Van Steenkiste, C, Descamps, B, Vanhove, C, Libbrecht, L, De Rycke, R, Lambrecht, BN, Geerts, A, Janssens, S, Van Vlierberghe, H. Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy Hepatol Int 9, 93-104, 2014. (Epub 2014 Oct 1)

Vandewynckel, YP, Laukens, D, Geerts, A, Vanhove, C, Descamps, B, Colle, I, Devisscher, L, Bogaerts, E, Paridaens, A, Verhelst, X, Van Steenkiste, C, Libbrecht, L, Lambrecht, BN, Janssens, S, Van Vlierberghe, H. Therapeutic effects of artesunate in hepatocellular carcinoma: repurposing an ancient antimalarial agent Eur J Gastroenterol Hepatol 26, 861-870, 2014. (Epub 2014 Jul)

Back to previous page

Export in CSV

Page 1 of 2
<< 1 - 2 >>

To top

What do these icons mean?

pdf file (800 kb)