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Publications by this IRC author

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Timmermans, S, Libert, C.
Coding variants in mouse and rat model organisms: mousepost and ratpost
Mamm Genome , in press, 2021. (Epub 2021 Jul 27)

Timmermans, S, Libert, C.
Ratpost: a searchable database of protein-inactivating sequence variations in 40 sequenced rat-inbred strains
Mamm Genome 32, 1-11, 2021. (Epub 2021 Jan 22)

Vandewalle, J, Timmermans, S, Paakinaho, V, Vancraeynest, L, Dewyse, L, Vanderhaeghen, T, Wallaeys, C, Van Wyngene, L, Van Looveren, K, Nuyttens, L, Eggermont, M, Dewaele, S, Velho, TR, Moita, LF, Weis, S, Sponholz, C, van Grunsven, LA, Dewerchin, M, Carmeliet, P, et al..
Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis
Cell Metab 33, 1-14, 2021. (Epub 2021 Jul 20)

Van Wyngene, L, Vanderhaeghen, T, Petta, I, Timmermans, S, Corbeels, K, Van der Schueren, B, Vandewalle, J, Van Looveren, K, Wallaeys, C, Eggermont, M, Dewaele, S, Catrysse, L, van Loo, G, Beyaert, R, Vangoitsenhoven, R, Nakayama, T, Tavernier, J, De Bosscher, K, Libert, C.
ZBTB32 performs crosstalk with the glucocorticoid receptor and is crucial in glucocorticoid responses to starvation
iScience 24, 102790, 2021. (Epub 2021 Jun 28)

Souffriau, J, Timmermans, S, Vanderhaeghen, T, Wallaeys, C, Van Looveren, K, Aelbrecht, L, Dewaele, S, Vandewalle, J, et al., Eggermont, M, De Rycke, R, De Bruyne, M, Ballegeer, M, Vandevyver, S, Hochepied, T, Beyaert, R, Libert, C.
Zinc inhibits lethal inflammatory shock by preventing microbe-induced interferon signature in intestinal epithelium
EMBO Mol Med , e11917, 2020. (Epub 2020 Sep 11)

Van Looveren, K, Timmermans, S, Vanderhaeghen, T, Wallaeys, C, Ballegeer, M, Souffriau, J, Eggermont, M, Vandewalle, J, Van Wyngene, L, De Bosscher, K, Libert, C.
Glucocorticoids limit lipopolysaccharide-induced lethal inflammation by a double control system
EMBO Rep 21, e49762, 2020. (Epub 2020 May 8)

Van Wyngene, L, Vanderhaeghen, T, Timmermans, S, Vandewalle, J, Van Looveren, K, Souffriau, J, Wallaeys, C, Eggermont, M, Ernst, S, Van Hamme, E, Goncalves, A, Eelen, G, Remmerie, A, Scott, CL, Rombouts, C, Vanhaecke, L, De Bus, L, Decruyenaere, J, Carmeliet, P, et al..
Hepatic PPARalpha function and lipid metabolic pathways are dysregulated in polymicrobial sepsis
EMBO Mol Med , e11319, 2020. (Epub 2020 Jan 9)

Dendoncker, K, Timmermans, S, Vandewalle, J, Eggermont, M, Lempiainen, J, Van Hamme, E, Dewaele, S, Vandevyver, S, Ballegeer, M, Souffriau, J, Van Wyngene, L, Van Looveren, K, Vanderhaeghen, T, Beyaert, R, De Bosscher, K, Palvimo, JJ, Van Montagu, M, Libert, C.
TNF-alpha inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile
Proc Natl Acad Sci U S A 116, 12942-12951, 2019. (Epub 2019 Jun 10)

Timmermans, S, Souffriau, J, Libert, C.
A General Introduction to Glucocorticoid Biology
Front Immunol 10, 1545, 2019. (Epub 2019 Jul 25)

Ballegeer, M, Van Looveren, K, Timmermans, S, Eggermont, M, Vandevyver, S, Thery, F, Dendoncker, K, Souffriau, J, Vandewalle, J, Van Wyngene, L, De Rycke, R, Takahashi, N, Vandenabeele, P, Tuckermann, J, Reichardt, HM, Impens, F, Beyaert, R, De Bosscher, K, Vandenbroucke, RE, et al..
Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice
J Clin Invest 128, 3265-3279, 2018. (Epub 2018 May 10)

Timmermans, S, Libert, C.
Easy Access to and Applications of the Sequences of All Protein-Coding Genes of All Sequenced Mouse Strains
Trends Genet 34, 899-902, 2018. (Epub 2018 Sep 19)

Timmermans, S, Libert, C.
Learning lessons in sepsis from the children
Mol Syst Biol 14, e8335, 2018. (Epub 2018 May 17)

Timmermans, S, Libert, C.
Overview of inactivating mutations in the protein-coding genome of the mouse reference strain C57BL/6J
JCI Insight 3, e121758, 2018. (Epub 2018 Jul 12)

Timmermans, S, Souffriau, J, Vandewalle, J, Van Wyngene, L, Van Looveren, K, Vanderhaeghen, T, Libert, C.
Using the inbred mouse strain SPRET/EiJ to provide novel insights in inflammation and infection research
Mamm Genome 29, 585-592, 2018. (Epub 2018 Aug)

Dendoncker, K, Timmermans, S, Van Looveren, K, De Cauwer, L, De Bosscher, K, Libert, C.
The nature of the GRE influences the screening for GR-activity enhancing modulators
PLoS One 12, 7, 2017. (Epub 2017 Jul 7)

Timmermans, S, Van Montagu, M, Libert, C.
Complete overview of protein-inactivating sequence variations in 36 sequenced mouse inbred strains
Proc Natl Acad Sci U S A 114, 9158-9163, 2017. (Epub 2017 Aug 7)

Steeland, S, Timmermans, S, Van Ryckeghem, S, Hulpiau, P, Saeys, Y, Van Montagu, M, Vandenbroucke, RE, Libert, C.
Efficient analysis of mouse genome sequences reveal many nonsense variants
Proc Natl Acad Sci U S A 113, 5670-5675, 2016. (Epub 2016 May 17)

Puimege, L, Van Hauwermeiren, F, Steeland, S, Van Ryckeghem, S, Vandewalle, J, Lodens, S, Dejager, L, Vandevyver, S, Staelens, J, Timmermans, S, Vandenbroucke, RE, Libert, C.
Glucocorticoid-induced microRNA-511 protects against TNF by down-regulating TNFR1
EMBO Mol Med 7, 1004-1017, 2015. (Epub 2015 May 20)

Singh, P, Dejager, L, Amand, M, Theatre, E, Vandereyken, M, Zurashvili, T, Singh, M, Mack, M, Timmermans, S, Musumeci, L, Dejardin, E, Mustelin, T, Van Ginderachter, JA, Moutschen, M, Oury, C, Libert, C, Rahmouni, S.
DUSP3 Genetic Deletion Confers M2-like Macrophage-Dependent Tolerance to Septic Shock
J Immunol 194, 4951-4962, 2015. (Epub 2015 Apr 15)

Timmermans, S, Van Hauwermeiren, F, Puimege, L, Dejager, L, Van Wonterghem, E, Vanhooren, V, Mestdagh, P, Libert, C, Vandenbroucke, RE.
Determining differentially expressed miRNAs and validating miRNA-target relationships using the SPRET/Ei mouse strain
Mamm Genome 26, 94-107, 2015. (Epub 2014 Dec 10)

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