Publications by this IRC author

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Lukasik, Z, Gracey, E, Venken, K, Ritchlin, C, Elewaut, D.
Crossing the boundaries: IL-23 and its role in linking inflammation of the skin, gut and joints
Rheumatology (Oxford) , in press, 2021. (Epub 2021 May 7)

De Smet, EG, Van Eeckhoutte, HP, Avila Cobos, F, Blomme, E, Verhamme, FM, Provoost, S, Verleden, SE, Venken, K, Maes, T, Joos, GF, Mestdagh, P, Brusselle, GG, Bracke, KR.
The role of miR-155 in cigarette smoke-induced pulmonary inflammation and COPD
Mucosal Immunol 13, 423-436, 2020. (Epub 2019 Dec 9)

Dumas, E, Venken, K, Rosenbaum, JT, Elewaut, D.
Intestinal Microbiota, HLA-B27, and Spondyloarthritis: Dangerous Liaisons
Rheum Dis Clin North Am 46, 213-224, 2020. (Epub 2020 May)

Govindarajan, S, Verheugen, E, Venken, K, Gaublomme, D, Maelegheer, M, Cloots, E, Gysens, F, De Geest, BG, Cheng, TY, Moody, DB, Janssens, S, Drennan, M, Elewaut, D.
ER stress in antigen-presenting cells promotes NKT cell activation through endogenous neutral lipids
EMBO Rep , e48927, 2020. (Epub 2020 May 3)

Lukasik, Z, Elewaut, D, Venken, K.
MAIT Cells Come to the Rescue in Cancer Immunotherapy?
Cancers (Basel) 12, 413, 2020. (Epub 2020 Feb 11)

Cambre, I, Gaublomme, D, Schryvers, N, Lambrecht, S, Lories, R, Venken, K, Elewaut, D.
Running promotes chronicity of arthritis by local modulation of complement activators and impairing T regulatory feedback loops
Ann Rheum Dis 78, 787-795, 2019. (Epub 2019 Mar 30)

Gilis, E, Gaublomme, D, Staal, J, Venken, K, Dhaenens, M, Lambrecht, S, Coudenys, J, Decruy, T, Schryvers, N, Driege, Y, Dumas, E, Demeyer, A, De Muynck, A, van Hengel, J, Van Hoorebeke, L, Deforce, D, Beyaert, R, Elewaut, D.
Deletion of Mucosa‐Associated Lymphoid Tissue Lymphoma Translocation Protein 1 in Mouse T Cells Protects Against Development of Autoimmune Arthritis but Leads to Spontaneous Osteoporosis
Arthritis Rheumatol 71, 2005-2015, 2019. (Epub 2019 Jul 1)

Janssens, J, Bitra, A, Wang, J, Decruy, T, Venken, K, van der Eycken, J, Elewaut, D, Zajonc, DM, van Calenbergh, S.
4"-O-Alkylated alpha-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies
ChemMedChem 14, 147-168, 2019. (Epub 2018 Dec 17)

Venken, K, Jacques, P, Mortier, C, Labadia, ME, Decruy, T, Coudenys, J, et al., Van Gassen, S, Martens, L, Smith, D, Harcken, C, Wahle, J, Wang, CT, Verheugen, E, Schryvers, N, Varkas, G, Cypers, H, et al.,Van den Bosch, F, Saeys, Y, Nabozny, G, Elewaut D.
RORgammat inhibition selectively targets IL-17 producing iNKT and gammadelta-T cells enriched in Spondyloarthritis patients
Nat Commun 10, 9, 2019. (Epub 2019 Jan 2)

De Bruyne, M, Bogaert, DJ, Venken, K, Van den Bossche, L, Bonroy, C, Roels, L, Tavernier, SJ, van de Vijver, E, Driessen, A, van Gijn, M, Gamez-Diaz, L, Elewaut, D, Grimbacher, B, Haerynck, F, Moes, N, Dullaers, M.
A novel LPS-responsive beige-like anchor protein (LRBA) mutation presents with normal CTLA-4 and overactive Th17 immunity
J Allergy Clin Immunol 142, 1968-1971, 2018. (Epub 2018 Sep 4)

Gilis, E, Mortier, C, Venken, K, Debusschere, K, Vereecke, L, Elewaut, D.
The Role of the Microbiome in Gut and Joint Inflammation in Psoriatic Arthritis and Spondyloarthritis
J Rheumatol Suppl 94, 36-39, 2018. (Epub 2018 Jun)

Mortier, C, Govindarajan, S, Venken, K, Elewaut, D.
It Takes "Guts" to Cause Joint Inflammation: Role of Innate-Like T Cells
Front Immunol 9, 1489, 2018. (Epub 2018 Jun 29)

Venken, K, Favreau, M, Gaublomme, D, Menu, E, Vanderkerken, K, Elewaut, D.
Checkpoint inhibition in the treatment of multiple myeloma: A way to boost innate-like T cell anti-tumor function?
Mol Immunol 101, 521-526, 2018. (Epub 2018 Aug 15)

Zhao, M, Svensson, MND, Venken, K, Chawla, A, Liang, S, Engel, I, Mydel, P, Day, J, Elewaut, D, Bottini, N, Kronenberg, M.
Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70
Nat Commun 9, 2627, 2018. (Epub 2018 Jul 6)

Favreau, M, Menu, E, Gaublomme, D, Vanderkerken, K, Faict, S, Maes, K, De Bruyne, E, Govindarajan, S, Drennan, M, Van Calenbergh, S, Leleu, X, Zabeau, L, Tavernier, J, Venken, K, Elewaut, D.
Leptin receptor antagonism of iNKT cell function: a novel strategy to combat multiple myeloma
Leukemia 31, 2678-2685, 2017. (Epub 2017 May 11)

Favreau, M, Venken, K, Faict, S, Maes, K, De Veirman, K, De Bruyne, E, Leleu, X, Boon, L, Elewaut, D, Vanderkerken, K, Menu, E.
Both mucosal- associated invariant and natural killer T cell deficiency in multiple myeloma can be countered by PD-1 inhibition
Haematologica 102, E266-E270, 2017. (Epub 2017 Apr 6)

Guillaume, J, Seki, T, Decruy, T, Venken, K, Elewaut, D, Tsuji, M, Van Calenbergh, S.
Synthesis of C6''-modified alpha-C-GalCer analogues as mouse and human iNKT cell agonists
Org Biomol Chem 15, 2217-2225, 2017. (Epub 2017 Feb 21)

Janssens, J, Decruy, T, Venken, K, Seki, T, Krols, S, Van der Eycken, J, Tsuji, M, Elewaut, D, Van Calenbergh, S.
Efficient Divergent Synthesis of New Immunostimulant 4''-Modified alpha-Galactosylceramide Analogues
ACS Med Chem Lett 8, 642-647, 2017. (Epub 2017 Jun 8)

Favreau, M, Vanderkerken, K, Elewaut, D, Venken, K, Menu, E.
Does an NKT-cell-based immunotherapeutic approach have a future in multiple myeloma?
Oncotarget 7, 23128-23140, 2016. (Epub 2016 Feb 17)

Venken, K, Elewaut, D.
IL-23 responsive innate-like T cells in spondyloarthritis: the less frequent they are, the more vital they appear
Curr Rheumatol Rep 17, 30, 2015. (Epub 2015 April 15)

Venken, K, Elewaut, D.
New immune cells in spondyloarthritis: Key players or innocent bystanders?
Best Pract Res Clin Rheumatol 29, 706-714, 2015. (Epub 2015 Dec)

Venken, K, Seeuws, S, Zabeau, L, Jacques, P, Decruy, T, Coudenys, J, Verheugen, E, Windels, F, Catteeuw, D, Drennan, M, Van Calenbergh, S, Lambrecht, BN, Yoshimura, A, Tavernier, J, Elewaut, D.
A bidirectional crosstalk between iNKT cells and adipocytes mediated by leptin modulates susceptibility for T cell mediated hepatitis
J Hepatol 60, 175-182, 2014. (Epub 2013 Aug 20)

Zabeau, L, Jensen, CJ, Seeuws, S, Venken, K, Verhee, A, Catteeuw, D, van Loo, G, Chen, H, Walder, K, Hollis, J, Foote, S, Morris, MJ, Van der Heyden, J, Peelman, F, Oldfield, BJ, Rubio, JP, Elewaut, D, Tavernier, J.
Leptin’s metabolic and immune functions can be uncoupled at the ligand/receptor interaction level
Cell Mol Life Sci 72, 629-644, 2014. (Epub 2014 Aug 7)

Venken, K, Decruy, T, Aspeslagh, S, Van Calenbergh, S, Lambrecht, BN, Elewaut, D.
Bacterial CD1d-restricted glycolipids induce IL-10 production by human regulatory T Cells upon cross-talk with invariant NKT cells
J Immunol 191, 2174-2183, 2013. (Epub 2013 Jul 29)