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Nuhn, L, Van Hoecke, L, Deswarte, K, Schepens, B, Li, Y, Lambrecht, BN, De Koker, S, David, SA, Saelens, X, De Geest, BG.
Potent anti-viral vaccine adjuvant based on pH-degradable nanogels with covalently linked small molecule imidazoquinoline TLR7/8 agonist
Biomaterials 178, 643-651, 2018. (Epub 2018 Mar 16)

Naessens, T, Schepens, B, Smet, M, Pollard, C, Van Hoecke, L, De Beuckelaer, A, Willart, M, Lambrecht, B, De Koker, S, Saelens, X, Grooten, J.
GM-CSF treatment prevents respiratory syncytial virus-induced pulmonary exacerbation responses in postallergic mice by stimulating alveolar macrophage maturation
J Allergy Clin Immunol 137, 700-709, 2016. (Epub 2015 Nov 9)

Zhang, Z, Schepens, B, Nuhn, L, Saelens, X, Schotsaert, M, Callewaert, N, De Rycke, R, Zhang, Q, Moins, S, Benali, S, Mespouille, L, Hoogenboom, R, De Geest, BG.
Influenza-binding sialylated polymer coated gold nanoparticles prepared via RAFT polymerization and reductive amination
Chem Commun (Camb) 52, 3352-3355, 2016. (Epub 2016 Jan 29)

Anastasina, M, Schepens, B, Soderholm, S, Nyman, TA, Matikainen, S, Saksela, K, Saelens, X, Kainov, DE.
The C-terminus of NS1 protein of influenza A/WSN/1933(H1N1) virus modulates antiviral responses in infected human macrophages and mice
J Gen Virol 96, 2086-2091, 2015. (Epub 2015 May 1)

Cho, KJ, Schepens, B, Moonens, K, Deng, L, Fiers, W, Remaut, H, Saelens, X.
Crystal structure of the conserved amino-terminus of the extracellular domain of matrix protein 2 of influenza A virus gripped by an antibody
J Virol 90, 611-615, 2015. (Epub 2015 Oct 14)

Cho, KJ, Schepens, B, Seok, JH, Kim, S, Roose, K, Lee, JH, Gallardo, R, Van Hamme, E, Schymkowitz, J, Rousseau, F, Fiers, W, Saelens, X, Kim, KH.
Structure of the Extracellular Domain of Matrix Protein 2 of Influenza A Virus in Complex with a Protective Monoclonal Antibody
J Virol 89, 3700-3711, 2015. (Epub 2015 Jan 21)

De Baets, S, Verhelst, J, Van den Hoecke, S, Smet, A, Schotsaert, M, Job, ER, Roose, K, Schepens, B, Fiers, W, Saelens, X.
A GFP Expressing Influenza A Virus to Report In Vivo Tropism and Protection by a Matrix Protein 2 Ectodomain-Specific Monoclonal Antibody
PLoS One 10, e0121491, 2015. (Epub 2015 Mar 27)

Kremer, A, Lippens, S, Bartunkova, S, Asselbergh, B, Blanpain, C, Fendrych, M, Goossens, A, Holt, M, Janssens, S, Krols, M, Larsimont, JC, Mc Guire, C, Nowack, MK, Saelens, X, Schertel, A, Schepens, B, Slezak, M, Timmerman, V, Theunis, C, et al..
Developing 3D SEM in a broad biological context
J Microsc 259, 80-96, 2015. (Epub 2015 Jan 26)

Schepens, B, Schotsaert, M, Saelens, X.
Small hydrophobic protein of respiratory syncytial virus as a novel vaccine antigen
Immunotherapy 7, 3, 2015. (Epub 2015 Mar)

Vermeire, T, Vermaere, S, Schepens, B, Saelens, X, Van Gucht, S, Martens, L, Vandermarliere, E.
Scop3D: Three-dimensional visualization of sequence conservation
Proteomics 15, 1448-1452, 2015. (Epub 2015 Jan 31)

Cardoso, FM, Ibanez, LI, Van den Hoecke, S, De Baets, S, Smet, A, Roose, K, Schepens, B, Descamps, FJ, Fiers, W, Muyldermans, S, Depicker, A, Saelens, X.
Single domain antibodies targeting neuraminidase protect against an H5N1 influenza virus challenge
J Virol 88, 8278-8296, 2014. (Epub 2014 May 14)

De Baets, S, Roose, K, Schepens, B, Saelens, X.
Presenting heterologous epitopes with hepatitis B core-based virus-like particles
In Virus-like Particles in Vaccine Development. (Buonaguro, FM, Buonaguro, L, eds.), London, Future Medicine Ltd. , pp. 68-84, 2014. (Epub 2014 Jan)

Rossey, I, Sedeyn, K, De Baets, S, Schepens, B, Saelens, X.
CD8+ T cell immunity against human respiratory syncytial virus
Vaccine 32, 6130-6137, 2014. (Epub Q2: 35/122)

Schepens, B, Sedeyn, K, Vande Ginste, L, De Baets, S, Schotsaert, M, Roose, K, Houspie, L, Van Ranst, M, Gilbert, B, van Rooijen, N, Fiers, W, Piedra, P, Saelens, X.
Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein
EMBO Mol Med 6, 1436-1454, 2014. (Epub 2014 Oct 8)

De Baets, S, Schepens, B, Sedeyn, K, Schotsaert, M, Roose, K, Bogaert, P, Fiers, W, Saelens, X.
Recombinant influenza virus carrying the RSV F85-93 CTL epitope reduces respiratory syncytial virus replication in mice
J Virol 87, 3314-3323, 2013. (Epub 2013 Jan 9)

Ibanez, LI, Roose, K, De Filette, M, Schotsaert, M, De Sloovere, J, Roels, S, Pollard, C, Schepens, B, Grooten, J, Fiers, W, Saelens, X.
M2e displaying virus-like particles with associated RNA promote T Helper 1 type adaptive immunity against Influenza A
PLoS One 8, e59081, 2013. (Epub 2013 Mar 18)

Roose, K, De Baets, S, Schepens, B, Saelens, X.
Presenting heterologous epitopes with hepatitis B core-based virus-like particles
Expert Rev Vaccines 12, 183-198, 2013. (Epub 2013 Feb)

Schotsaert, M, Ysenbaert, T, Neyt, K, Ibanez, LI, Bogaert, P, Schepens, B, Lambrecht, BN, Fiers, W, Saelens, X.
Natural and long-lasting cellular immune responses against influenza in the M2e-immune host
Mucosal Immunol 6, 276-287, 2013. (Epub 2012 Jul 18)

Cardoso, FML, Ibañez, L.I., Schepens, B., Saelens, X..
Single domain camelid antibodies that neutralize negative strand viruses
In Antiviral Drugs, Aspects of Clinical Use and Recent Advances. (Arbuthnot, P, ed.), Rijeka, InTech, pp. 151-170, 2012. (Epub )

Roose, K, Schotsaert, M, El Bakkouri, K, Schepens, B, Fiers, W, Saelens, X.
Cutting edge approaches towards novel and cross-protective influenza vaccines
In Development of novel vaccines. (von Gabain, A, Klade, C, eds.), Wien, Springer-Verlag, pp. 205-233, 2012. (Epub )

Verhelst, J, Parthoens, E, Schepens, B, Fiers, W, Saelens, X.
Interferon-inducible Mx1 protein inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly
J Virol 86, 13445-13455, 2012. (Epub 2012 Sep 26)

De Filette, M, Ysenbaert, T, Roose, K, Schotsaert, M, Roels, S, Goossen, E, Schepens, B, Fiers, W, Saelens, X.
Antiserum against the conserved nine-amino-acid N-terminal peptide of influenza A virus matrix protein 2 is not immuno-protective
J Gen Virol 92, 301-306 , 2011. (Epub 2010 Oct 21)

Hultberg, A, Temperton, NJ, Rosseels, V, Koenders, M, Gonzalez-Pajuelo, M, Schepens, B, Ibanez, LI, Vanlandschoot, P, Schillemans, J, Saunders, M, Weiss, RA, Saelens, X, Melero, JA, Verrips, CT, Van Gucht, S, de Haard, HJ.
Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules
PLoS One 6, e17665, 2011. (Epub 2011 Apr 1)

Ibanez, LI, De Filette, M, Hultberg, A, Verrips, T, Temperton, N, Weiss, RA, Vandevelde, W, Schepens, B, Vanlandschoot, P, Saelens, X.
Nanobodies with in vitro neutralizing activity protect mice against H5N1 Influenza virus infection
J Infect Dis 203, 1063-1072, 2011. (Epub 2011 Apr)

Schepens, B, Ibanez, LI, De Baets, S, Hultberg, A, Bogaert, P, De Bleser, P, Vervalle, F, Verrips, T, Melero, J, Vandevelde, W, Vanlandschoot, P, Saelens, X.
Nanobodies(R) specific for Respiratory Syncytial Virus fusion protein protect against infection by inhibition of fusion
J Infect Dis 204, 1692-1701, 2011. (Epub 2011 Oct 12)

Vanlandschoot, P, Stortelers, C, Beirnaert, E, Ibanez, LI, Schepens, B, Depla, E, Saelens, X.
Nanobodies(R): New ammunition to battle viruses
Antiviral Res 92, 389-407, 2011. (Epub 2011 Sep 10)

Lampo, E, Duchateau, L, Schepens, B, Van Poucke, M, Saelens, X, Erkens, T, Van Zeveren, A, Peelman, LJ.
Identification of polymorphisms in the ovine Shadow of prion protein (SPRN) gene and assessment of their effect on promoter activity and susceptibility for classical scrapie
Anim Genet 41, 169-178, 2010. (Epub 2009 Nov 16)

Fiers, W, De Filette, M, El Bakkouri, K, Schepens, B, Roose, K, Schotsaert, M, Birkett, A, Saelens, X.
M2e-based universal influenza A vaccine
Vaccine 27, 6280-6283, 2009. (Epub 2009 Oct 23)

Schepens, B, Tinton, SA, Bruynooghe, Y, Parthoens, E, Haegman, M, Beyaert, R, Cornelis, S.
A role for hnRNP C1/C2 and Unr in internal initiation of translation during mitosis
EMBO J 26, 158-69, 2007. (Epub 2006 Dec 7)

Cornelis, S, Tinton, SA, Schepens, B, Bruynooghe, Y, Beyaert, R.
UNR translation can be driven by an IRES element that is negatively regulated by polypyrimidine tract binding protein
Nucleic Acids Res 33, 3095-3108, 2005. (Epub ---)

Schepens, B, Tinton, S, Bruynooghe, Y, Beyaert, R, Cornelis, S.
The polypyrimidine tract binding protein stimulates HIF-1alpha IRES-mediated translation during hypoxia
Nucl Acids Res 33, 6884-6894, 2005. (Epub 2005 Dec 7)

Tinton, SA, Schepens, B, Bruynooghe, Y, Beyaert, R, Cornelis, S.
Regulation of the cell cycle-dependent PITSLRE internal ribosome entry site: roles of Unr (Upstream of N-ras) and phosphorylated translation initiation factor eIF-2alpha
Biochem J 385, 155-163, 2005. (Epub ---)

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