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Aegerter, H, Smole, U, Heyndrickx, I, Verstraete, K, Savvides, SN, Hammad, H, Lambrecht, BN.
Charcot-Leyden crystals and other protein crystals driving type 2 immunity and allergy
Curr Opin Immunol 72, 72-78, 2021. (Epub 2021 Apr 16)

Almeida, L, Dhillon-LaBrooy, A, Castro, CN, Adossa, N, Carriche, GM, Guderian, M, Lippens, S, Dennerlein, S, Hesse, C, Lambrecht, BN, Berod, L, Schauser, L, Blazar, BR, Kalesse, M, Muller, R, Moita, LF, Sparwasser, T.
Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis
Immunity 54, 68-83, 2021. (Epub 2020 Nov 24)

Backers, L, Parton, B, De Bruyne, M, Tavernier, SJ, Van Den Bogaert, K, Lambrecht, BN, Haerynck, F, Claes, KBM.
Missing heritability in Bloom syndrome: First report of a deep intronic variant leading to pseudo-exon activation in the BLM gene
Clin Genet 99, 292-297, 2021. (Epub 2020 Oct 9)

Bosteels, C, Fierens, K, De Prijck, S, Van Moorleghem, J, Vanheerswynghels, M, De Wolf, C, Chalon, A, Collignon, C, Hammad, H, Didierlaurent, AM, Lambrecht, BN.
CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Immunity by the Human Vaccine Adjuvant System AS01
Front Immunol 11, 606805, 2021. (Epub 2021 Jan 14)

Brightling, C, Kulkarni, S, Lambrecht, BN, Sandham, D, Weiss, M, Altman, P.
The pharmacology of the prostaglandin D2 receptor 2 (DP2) receptor antagonist, fevipiprant
Pulm Pharmacol Ther 68, 102030, 2021. (Epub 2021 Apr 4)

Cloots, E, Debeuf, N, Deswarte, K, Fayazpour, F, Vanheerswynghels, M, De Wolf, C, Van De Velde, E, Hammad, H, Lambrecht, BN, Eyckerman, S, Janssens, S.
IRE1beta does not affect mucus secretion during allergic asthma development in a house dust mite murine model
Allergy , in press, 2021. (Epub 2021 Aug 12)

de Reuver, R, Dierick, E, Wiernicki, B, Staes, K, Seys, L, De Meester, E, Muyldermans, T, Botzki, A, Lambrecht, BN, Van Nieuwerburgh, F, Vandenabeele, P, Maelfait, J.
ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation
Cell Rep 36, 109500, 2021. (Epub 2021 Aug 10)

De Vrieze, J, Baptista, AP, Nuhn, L, Van Herck, S, Deswarte, K, Yu, HJ, Lambrecht, BN, De Geest, BG.
Lipid Nature and Alkyl Length Influence Lymph Node Accumulation of Lipid-Polyethylene Glycol Amphiphiles
Advanced Therapeutics , in press, 2021. (Epub 2021 Jul 26)

Dhont, S, Derom, E, Van Braeckel, E, Depuydt, P, Lambrecht, BN.
Conceptions of the pathophysiology of happy hypoxemia in COVID-19
Respir Res 22, 12, 2021. (Epub 2021 Jan 8)

Hammad, H, Lambrecht, BN.
The basic immunology of asthma
Cell 184, 1469-1485, 2021. (Epub 2021 Mar 18)

Jangra, S, De Vrieze, J, Choi, A, Rathnasinghe, R, Laghlali, G, Uvyn, A, Van Herck, S, Nuhn, L, Deswarte, K, Zhong, Z, Sanders, N, Lienenklaus, S, David, S, Strohmeier, S, Amanat, F, Krammer, F, Hammad, H, Lambrecht, BN, Coughlan, L, et al..
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine
Angew Chem Int Ed Engl 60, 9467-9473, 2021. (Epub 2021 Jan 19)

Meyts, I, Bucciol, G, Quinti, I, Neven, B, Fischer, A, Seoane, E, Lopez-Granados, E, Gianelli, C, Robles-Marhuenda, A, Jeandel, PY, Paillard, C, Sankaran, VG, Demirdag, YY, et al, Bosteels, C, Lambrecht, BN, et al..
Coronavirus Disease 2019 in patients with inborn errors of immunity: an international study
J Allergy Clin Immunol 147, 520-531, 2021. (Epub 2020 Sep 24)

Oikonomou, N, Schuijs, MJ, Chatzigiagkos, A, Androulidaki, A, Aidinis, V, Hammad, H, Lambrecht, BN, Pasparakis, M.
Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation
Mucosal Immunol , in press, 2021. (Epub 2021 May 27)

Vanderkerken, M, Baptista, AP, De Giovanni, M, Fukuyama, S, Browaeys, R, Scott, CL, Norris, PS, Eberl, G, Di Santo, JP, Vivier, E, Saeys, Y, Hammad, H, Cyster, JG, Ware, CF, Tumanov, AV, De Trez, C, Lambrecht, BN.
ILC3s control splenic cDC homeostasis via lymphotoxin signaling
J Exp Med 218, e20190835, 2021. (Epub 2021 Mar 16)

Van Lysebetten, D, Malfanti, A, Deswarte, K, Koynov, K, Golba, B, Ye, T, Zhong, Z, Kasmi, S, Lamoot, A, Chen, Y, Van Herck, S, Lambrecht, BN, Sanders, NN, Lienenklaus, S, David, SA, Vicent, MJ, De Koker, S, De Geest, BG.
Lipid-Polyglutamate Nanoparticle Vaccine Platform
ACS Appl Mater Interfaces 13, 6011-6022, 2021. (Epub 2021 Jan 28)

Vidal-Quist, JC, Vidal, C, Escolar, F, Lambrecht, BN, Rombauts, S, Hernandez-Crespo, P.
RNA viruses in the house dust mite Dermatophagoides pteronyssinus, detection in environmental samples and in commercial allergen extracts used for in vivo diagnosis
Allergy , in press, 2021. (Epub 2021 Apr 29)

Bachert, C, Marple, B, Schlosser, RJ, Hopkins, C, Schleimer, RP, Lambrecht, BN, Broker, BM, Laidlaw, T, Song, WJ.
Adult chronic rhinosinusitis
Nat Rev Dis Primers 6, 86, 2020. (Epub 2020 Oct 29)

Beziat, V, Tavernier, SJ, Chen, YH, Ma, CS, Materna, M, Laurence, A, Staal, J, Aschenbrenner, D, Roels, L, Worley, L, Claes, K, Gartner, L, Kohn, LA, De Bruyne, M, Schmitz-Abe, K, Charbonnier, LM, Keles, S, Nammour, J, Vladikine, N, et al..
Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome
J Exp Med 217, e20191804, 2020. (Epub 2020 Mar 24)

Bogaert, DJ, Laureys, G, Naesens, L, Mazure, D, De Bruyne, M, Hsu, AP, Bordon, V, Wouters, E, Tavernier, SJ, Lambrecht, BN, De Baere, E, Haerynck, F, Kerre, T.
GATA2 deficiency and haematopoietic stem cell transplantation: challenges for the clinical practitioner
Br J Haematol 188, 768-773, 2020. (Epub 2019 Nov 11)

Bosteels, C, Maes, B, Van Damme, K, De Leeuw, E, Declercq, J, Delporte, A, Demeyere, B, Vermeersch, S, Vuylsteke, M, Willaert, J, Bolle, L, Vanbiervliet, Y, Decuypere, J, Libeer, F, Vandecasteele, S, Peene, I, Lambrecht, B.
Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial
Trials 21, 491, 2020. (Epub 2020 Jun 5)

Del Valle, JR, Betts, BC, Yu, XZ, Janssens, S, Lambrecht, BN, Simon, MC, Hu, CA.
Clarifying the translational potential of B-I09
Nat Chem Biol 16, 1152, 2020. (Epub 2020 Oct 16)

Devos, T, Geukens, T, Schauwvlieghe, A, Arien, KK, Barbezange, C, Cleeren, M, Compernolle, V, Dauby, N, Desmecht, D, Grimaldi, D, Lambrecht, BN, Luyten, A, Maes, P, Moutschen, M, Romano, M, Seyler, L, Nevessignsky, MT, Vandenberghe, K, van Griensven, J, et al..
A randomized, multicentre, open-label phase II proof-of-concept trial investigating the clinical efficacy and safety of the addition of convalescent plasma to the standard of care in patients hospitalized with COVID-19: the Donated Antibodies Working against nCoV (DAWn-Plasma) trial
Trials 21, 981, 2020. (Epub 2020 Nov 27)

Dhont, S, Derom, E, Van Braeckel, E, Depuydt, P, Lambrecht, BN.
The pathophysiology of 'happy' hypoxemia in COVID-19
Respir Res 21, 198, 2020. (Epub 2020 JUl 28)

Gevaert, E, Delemarre, T, De Volder, J, Zhang, N, Holtappels, G, De Ruyck, N, Persson, E, Heyndrickx, I, Verstraete, K, Aegerter, H, Nauwynck, H, Savvides, SN, Lambrecht, BN, Bachert, C.
Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis
J Allergy Clin Immunol 145, 427-430, 2020. (Epub 2019 Sep 4)

Hammad, H, Lambrecht, BN.
Rbm7 in Structural Cells: A NEAT Way to Control Fibrosis
Immunity 52, 429-431, 2020. (Epub 2020 Mar 17)

Hammad, H, Lambrecht, BN.
Wnt and Hippo pathways in regulatory T cells: a NOTCH above in asthma
Nat Immunol 21, 13131314, 2020. (Epub 2020 Sep 23)

Jangra, S, De Vrieze, J, Choi, A, Rathnasinghe, R, Laghlali, G, Uvyn, A, Van Herck, S, Nuhn, L, Deswarte, K, Zhong, Z, Sanders, N, Lienenklaus, S, David, S, Strohmeier, S, Amanat, F, Krammer, F, Hammad, H, Lambrecht, BN, Coughlan, L, et al..
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine
bioRxiv , , 2020. (Epub 2020 Oct 23)

Kerr, SC, Gonzalez, JR, Schanin, J, Peters, MC, Lambrecht, BN, Brock, EC, Charbit, A, Ansel, KM, Youngblood, BA, Fahy, JV.
An Anti-Siglec-8 Antibody Depletes Sputum Eosinophils from Asthmatic Subjects and Inhibits Lung Mast Cells
Clin Exp Allergy 50, 904-914, 2020. (Epub 2020 Jun 15)

Li, Z, Oh, H, Cung, M, Marquez, SJ, Sun, J, Hammad, H, Janssens, S, Pouliot, P, Lambrecht, BN, Yang, YS, Shim, JH, Greenblatt, MB.
TAOK3 is a MAP3K contributing to osteoblast differentiation and skeletal mineralization
Biochem Biophys Res Commun 531, 497-502, 2020. (Epub 2020 Aug 14)

Maes, B, Bosteels, C, De Leeuw, E, Declercq, J, Van Damme, K, Delporte, A, Demeyere, B, Vermeersch, S, Vuylsteke, M, Willaert, J, Bolle, L, Vanbiervliet, Y, Decuypere, J, Libeer, F, Vandecasteele, S, Peene, I, Lambrecht, B.
Treatment of severely ill COVID-19 patients with anti-interleukin drugs (COV-AID): A structured summary of a study protocol for a randomised controlled trial
Trials 21, 468, 2020. (Epub 2020 Jun 3)

Naessens, T, Morias, Y, Hamrud, E, Gehrmann, U, Budida, R, Mattsson, J, Baker, T, Skogberg, G, Israelsson, E, Thorn, K, Schuijs, MJ, Angermann, B, Melville, F, Staples, KJ, Cunoosamy, DM, Lambrecht, BN.
Human Lung Conventional Dendritic Cells Orchestrate Lymphoid Neogenesis During COPD
Am J Respir Crit Care Med 202, 535-548, 2020. (Epub 2020 Apr 7)

Osier, F, Ting, JPY, Fraser, J, Lambrecht, BN, Romano, M, Gazzinelli, RT, Bortoluci, KR, Zamboni, DS, Akbar, AN, Evans, J, Brown, DE, Patel, KD, Wu, Y, Perez, AB, Perez, O, Kamradt, T, Falk, C, Barda-Saad, M, Ariel, A, et al..
The global response to the COVID-19 pandemic: how have immunology societies contributed?
Nat Rev Immunol 20, 594-602, 2020. (Epub 2020 Sep 10)

Slowicka, K, Petta, I, Blancke, G, Hoste, E, Dumas, E, Sze, M, Vikkula, H, Radaelli, E, Haigh, J, Jonckheere, S, Taminau, J, Vandamme, N, Wullaert, A, Tulchinsky, E, Nittner, D, Van Vlierberghe, P, De Hertogh, G, Baldin, P, Etlioglu, E, et al. Berx, G, Vereecke, L, van Loo,G.
Zeb2 drives invasive and microbiota-dependent colon carcinoma
Nature Cancer 1, 620-634, 2020. (Epub 2020 Jun 15)

Trocha, KM, Kip, P, Tao, M, MacArthur, MR, Trevino-Villarreal, H, Longchamp, A, Toussaint, W, Lambrecht, BN, de Vries, MR, Quax, PHA, Mitchell, JR, Ozaki, CK.
Short-Term Preoperative Protein Restriction Attenuates Vein Graft Disease via Induction of Cystathionine Upsilon-Lyase
Cardiovasc Res 116, 416428, 2020. (Epub 2019 Mar 29)

Vanderkerken, M, Maes, B, Vandersarren, L, Toussaint, W, Deswarte, K, Vanheerswynghels, M, Pouliot, P, Martens, L, Van Gassen, S, Arthur, CM, Kirkling, ME, Reizis, B, Conrad, D, Stowell, S, Hammad, H, Lambrecht, BN.
TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells
Proc Natl Acad Sci U S A 117, 31331-31342, 2020. (Epub 2020 Nov 19)

Vlaminck, S, Acke, F, Prokopakis, E, Speleman, K, Kawauchi, H, van Cutsem, JC, Hellings, PW, Jorissen, M, Seys, S, Bachert, C, Zele, TV, Lambrecht, BN, Gevaert, P.
Surgery in Nasal Polyp Patients: Outcome After a Minimum Observation of 10 Years
Am J Rhinol Allergy in press, , 2020. (Epub 2020 Oct 5)

Vroman, H, van Uden, D, Bergen, IM, van Hulst, JAC, Lukkes, M, van Loo, G, Clausen, BE, Boon, L, Lambrecht, BN, Hammad, H, Hendriks, RW, Kool, M.
Tnfaip3 expression in pulmonary conventional type 1 Langerin-expressing dendritic cells regulates T helper 2-mediated airway inflammation in mice
Allergy 75, 2587-2598, 2020. (Epub 2020 Apr 23)

Wang, B, Van Herck, S, Chen, Y, Bai, X, Zhong, Z, Deswarte, K, Lambrecht, BN, Sanders, NN, Lienenklaus, S, Scheeren, HW, David, SA, Kiessling, F, Lammers, T, De Geest, BG, Shi, Y.
Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles
J Am Chem Soc 142, 12133-12139, 2020. (Epub 2020 Jun 11)

Bonnardel, J, T'Jonck, W, Gaublomme, D, Browaeys, R, Scott, CL, Martens, L, Vanneste, B, De Prijck, S, Nedospasov, SA, Kremer, A, Van Hamme, E, Borghgraef, P, Toussaint, W, De Bleser, P, Mannaerts, I, Beschin, A, van Grunsven, LA, Lambrecht, BN, Taghon, T, et al..
Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche
Immunity 51, 638-654, 2019. (Epub 2019 Sep 24)

Debeuf, N, Zhakupova, A, Steiner, R, Van Gassen, S, Deswarte, K, Fayazpour, F, Van Moorleghem, J, Vergote, K, Pavie, B, Lemeire, K, Hammad, H, Hornemann, T, Janssens, S, Lambrecht, BN.
The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice
J Allergy Clin Immunol 144, 1648-1659, 2019. (Epub 2019 Jul 20)

Deckers, J, Lambrecht, BN, Hammad, H.
How a farming environment protects from atopy
Curr Opin Immunol 60, 163-169, 2019. (Epub 2019 Sep 6)

De Vrieze, J, Louage, B, Deswarte, K, Zhong, Z, De Coen, R, Van Herck, S, Nuhn, L, Frich, CK, Zelikin, A, Lienenklaus, S, Sanders, N, David, S, Lambrecht, B, de Geest, B.
Potent lymphatic translocation and spatial control over innate immune activation by polymer-lipid amphiphile conjugates of small molecule TLR7/8 agonists
Angew Chem Int Ed Engl 58, 15390-15395, 2019. (Epub 2019 Aug 9)

Gil-Cruz, C, Perez-Shibayama, C, De Martin, A, Ronchi, F, van der Borght, K, Niederer, R, Onder, L, Lutge, M, Novkovic, M, Nindl, V, Ramos, G, Arnoldini, M, Slack, EMC, Boivin-Jahns, V, Jahns, R, Wyss, M, Mooser, C, Lambrecht, BN, Maeder, MT, et al..
Microbiota-derived peptide mimics drive lethal inflammatory cardiomyopathy
Science 366, 881-886, 2019. (Epub 2019 Nov 15)

Haspeslagh, E, Vanheerswynghels, M, Deswarte, K, van Moorleghem, J, Jacquet, A, Lambrecht, BN, Hammad, H.
Prophylactic allergen immunotherapy with Der p 2 prevents murine asthma by regulating lung GM-CSF
J Allergy Clin Immunol 143, 2307-2311.e5, 2019. (Epub 2019 Feb 20)

Holgado, A, Braun, H, Van Nuffel, E, Detry, S, Schuijs, MJ, Deswarte, K, Vergote, K, Haegman, M, Baudelet, G, Haustraete, J, Hammad, H, Lambrecht, BN, Savvides, SN, Afonina, IS, Beyaert, R.
IL-33trap is a novel IL-33 neutralizing biologic that inhibits allergic airway inflammation
J Allergy Clin Immunol 144, 204-215, 2019. (Epub 2019 Mar 12)

Lambrecht, BN, Hammad, H, Fahy, JV.
The Cytokines of Asthma
Immunity 50, 975-991, 2019. (Epub 2019 Apr 16)

Momtazi, G, Lambrecht, BN, Naranjo, JR, Schock, BC.
Regulators of A20 (TNFAIP3) - new drug-able targets in inflammation
Am J Physiol Lung Cell Mol Physiol 316, L456-L469, 2019. (Epub 2018 Dec 13)

Persson, EK, Verstraete, K, Heyndrickx, I, Gevaert, E, Aegerter, H, Percier, JM, Deswarte, K, Verschueren, KHG, Dansercoer, A, Gras, D, Chanez, P, Bachert, C, Goncalves, A, Van Gorp, H, De Haard, H, Blanchetot, C, Saunders, M, Hammad, H, Savvides, SN, Lambrecht, BN.
Protein crystallization promotes type 2 immunity and is reversible by antibody treatment
Science 364, , 2019. (Epub 2019 May 24)

Schuijs, MJ, Hammad, H, Lambrecht, BN.
Professional and 'Amateur' Antigen-Presenting Cells In Type 2 Immunity
Trends Immunol 40, 22-34, 2019. (Epub 2018 Nov 27)

Tavernier, SJ, Athanasopoulos, V, Verloo, P, Behrens, G, Staal, J, Bogaert, DJ, Naesens, L, De Bruyne, M, Van Gassen, S, Parthoens, E, Ellyard, J, Cappello, J, Morris, LX, Van Gorp, H, Van Isterdael, G, Saeys, Y, Lamkanfi, M, Schelstraete, P, Dehoorne, J, et al..
A human immune dysregulation syndrome characterized by severe hyperinflammation with a homozygous nonsense Roquin-1 mutation
Nat Commun 10, 4779, 2019. (Epub 2019 oct 21)

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