» Home » Research 
Print this pageEmail this page URLConvert this page to PDF

Publications by this IRC author

(Publications from the same author but with another affiliation than IRC cannot be displayed here)

For copyright reasons, PDF-versions of our publications are available on the intranet only (login required  ). If you would like to receive a reprint of an IRC paper, please copy/paste the reference in the
reprint request form 


Click the UGent logo to retrieve publications of Rudi Beyaert in the UGent bibliography

Penning, LC, Schipper, RG, Vercammen, D, Verhofstad, AAJ, Denecker, T, Beyaert, R, Vandenabeele, P.
Sensitization of TNF-induced apoptosis with polyamine synthesis inhibitors in different human and murine tumour cell lines
Cytokine 10, 423-431, 1998. (Epub ---)

Schotte, P, Van Criekinge, W, Van de Craen, M, van Loo, G, Desmedt, M, Grooten, J, Cornelissen, M, De Ridder, L, Vandekerckhove, J, Fiers, W, Vandenabeele, P, Beyaert, R.
Cathepsin B-mediated activation of the proinflammatory caspase-11
Biochem Biophys Res Commun 251, 379-387, 1998. (Epub ---)

Van Criekinge, W, Smits, E, Burvenich, C, Beyaert, R.
Is er leven na de (cel)dood?
Vlaams Diergeneeskundig Tijdschrift 67, 278-283, 1998. (Epub ---)

Van Criekinge, W, van Gurp, M, Decoster, E, Schotte, P, Van de Craen, M, Fiers, W, Vandenabeele, P, Beyaert, R.
Use of the yeast three-hybrid system as a tool to study caspases
Anal Biochem 263, 62-66, 1998. (Epub ---)

Vercammen, D, Beyaert, R, Denecker, G, Goossens, V, van Loo, G, Declercq, W, Grooten, J, Fiers, W, Vandenabeele, P.
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
J Exp Med 187, 1477-1485, 1998. (Epub ---)

Barge, RMY, Willemze, R, Vandenabeele, P, Fiers, W, Beyaert, R.
Differential involvement of caspases in apoptosis of myeloid leukemic cells induced by chemotherapy versus growth withdrawal
FEBS Lett 409, 207-210, 1997. (Epub ---)

Beyaert, R, Kidd, VJ, Cornelis, S, Van de Craen, M, Denecker, G, Lahti, JM, Gururajan, R, Vandenabeele, P, Fiers, W.
Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor
J Biol Chem 272, 11694-11697, 1997. (Epub ---)

Decoster, E, Vandevoorde, V, Beyaert, R, Haegeman, G, Fiers, W.
Resistance to tumor necrosis factor (TNF) cytotoxicity by autocrine TNF production is independent of intracellular signaling pathways
FEBS Lett 416, 183-186, 1997. (Epub ---)

Denecker, G, Vandenabeele, P, Grooten, J, Penning, LC, Declercq, W, Beyaert, R, Buurman, WA, Fiers, W.
Differential role of calcium in tumour necrosis factor-mediated apoptosis and secretion of granulocyte-macrophage colony-stimulating factor in a T cell hybridoma
Cytokine 9, 631-638, 1997. (Epub ---)

De Valck, D, Heyninck, K, Van Criekinge, W, Vandenabeele, P, Fiers, W, Beyaert, R.
A20 inhibits NF-kB activation independently of binding to 14-3-3 proteins
Biochem Biophys Res Commun 238, 590-594, 1997. (Epub ---)

Fiers, W, Beyaert, R, Boone, E, Declercq, W, Decoster, E, De Valck, D, Goossens, V, Grooten, J, Haegeman, G, Heyninck, K, Penning, L, Plaisance, S, Van de Craen, M, Vandenabeele, P, Vanden Berghe, W, Vandevoorde, V, Vercammen, D.
Tumour necrosis factor: Intracellular mechanism of action
In HIV and Cytokines. (Guenounou, M, ed.), Paris, INSERM, pp. 33-41 , 1997. (Epub ---)

Van de Craen, M, Vandenabeele, P, Declercq, W, Van den brande, I, van Loo, G, Molemans, F, Schotte, P, Van Criekinge, W, Beyaert, R, Fiers, W.
Characterization of seven murine caspase family members
FEBS Lett 403, 61-69, 1997. (Epub ---)

Van de Craen, M, Van den brande, I, Declercq, W, Irmler, M, Beyaert, R, Tschopp, J, Fiers, W, Vandenabeele, P.
Cleavage of caspase family members by granzyme B: A comparative study in vitro
Eur J Immunol 27, 1296-1299, 1997. (Epub ---)

Vercammen, D, Vandenabeele, P, Beyaert, R, Declercq, W, Fiers, W.
Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells
Cytokine 9, 801-808, 1997. (Epub ---)

Wallach, D, Boldin, M, Varfolomeev, E, Beyaert, R, Vandenabeele, P, Fiers, W.
Cell death induction by receptors of the TNF family: Towards a molecular understanding
FEBS Lett 410, 96-106, 1997. (Epub ---)

Beyaert, R, Cuenda, A, Vanden Berghe, W, Plaisance, S, Lee, JC, Haegeman, G, Cohen, P, Fiers, W.
The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis in response to tumour necrosis factor
EMBO J 15, 1914-1923, 1996. (Epub ---)

De Valck, D, Heyninck, K, Van Criekinge, W, Contreras, R, Beyaert, R, Fiers, W.
A20, an inhibitor of cell death, self-associates by its zinc finger domain
FEBS Lett 384, 61-64, 1996. (Epub ---)

Fiers, W, Beyaert, R, Boone, E, Cornelis, S, Declercq, W, Decoster, E, Denecker, G, Depuydt, B, De Valck, D, De Wilde, G, Goossens, V, Grooten, J, Haegeman, G, Heyninck, K, Penning, L, Plaisance, S, Vancompernolle, K, Van Criekinge, W, Vandenabeele, P, et al..
TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis
J Inflamm 47, 67-75, 1996. (Epub ---)

Niki, T, Schuppan, D, de Bleser, PJ, Vrijsen, R, Pipeleers-Marichal, M, Beyaert, R, Wisse, E, Geerts, A.
Dexamethasone alters messenger RNA levels but not synthesis of collagens, fibronectin, or laminin by cultured rat fat-storing cells
Hepatology 23, 1673-1681, 1996. (Epub ---)

Van Criekinge, W, Beyaert, R, Van de Craen, M, Vandenabeele, P, Schotte, P, De Valck, D, Fiers, W.
Functional characterization of the prodomain of interleukin-1b-converting enzyme
J Biol Chem 271, 27245-27248, 1996. (Epub ---)

Beyaert, R, Vanhaesebroeck, B, Declercq, W, Van Lint, J, Vandenabeele, P, Agostinis, P, Vandenheede, JR, Fiers, W.
Casein kinase-1 phosphorylates the p75 tumor necrosis factor receptor and negatively regulates tumor necrosis factor signaling for apoptosis
J Biol Chem 270, 23293-23299, 1995. (Epub ---)

Vandenabeele, P, Declercq, W, Beyaert, R, Fiers, W.
Two tumour necrosis factor receptors: Structure and function
Trends Cell Biol 5, 392-399, 1995. (Epub ---)

Beyaert, R, Fiers, W.
Molecular mechanisms of tumor necrosis factor-induced cytotoxicity: What we do understand and what we do not
FEBS Lett 340, 9-16, 1994. (Epub ---)

Vandenabeele, P, Goossens, V, Beyaert, R, Declercq, W, Grooten, J, Vanhaesebroeck, B, Van de Craen, M, Vercammen, D, Depuydt, B, Denecker, G, Fiers, W.
Functional requirement of the two TNF receptors for induction of apoptosis in PC60 cells and the role of mitochondria in TNF-induced cytotoxicity
Circ Shock 44, 196-200, 1994. (Epub ---)

Beyaert, R, Heyninck, K, De Valck, D, Boeykens, F, Van Roy, F, Fiers, W.
Enhancement of tumor necrosis factor cytotoxicity by lithium chloride is associated with increased inositol phosphate accumulation
J Immunol 151, 291-300, 1993. (Epub ---)

Beyaert, R, Vanhaesebroeck, B, Heyninck, K, Boone, E, De Valck, D, Schulze-Osthoff, K, Haegeman, G, Van Roy, F, Fiers, W.
Sensitization of tumor cells to tumor necrosis factor action by the protein kinase inhibitor staurosporine
Cancer Res 53, 2623-2630, 1993. (Epub ---)

De Valck, D, Beyaert, R, Van Roy, F, Fiers, W.
Tumor necrosis factor cytotoxicity is associated with activation of cellular phospholipases
In New Developments in Lipid-Protein Interactions and Receptor Function. (Wirtz, KWA, Packer, L, Gustafsson, JÅ, Evangelopoulos, AE, Changeux, JP, eds.), NATO ASI Series, Vol. A 246, New York-London, Plenum Press, pp. 29-37, 1993. (Epub ---)

De Valck, D, Beyaert, R, Van Roy, F, Fiers, W.
Tumor necrosis factor cytotoxicity is associated with phospholipase D activation
Eur J Biochem 212, 491-497, 1993. (Epub ---)

Fiers, W, Beyaert, R, Brouckaert, P, Cauwels, A, Declercq, W, De Valck, D, Everaerdt, B, Goossens, V, Grooten, J, Haegeman, G, Libert, C, Schulze-Osthoff, K, Takahashi, N, Vandenabeele, P, Vanhaesebroeck, B, Van Ostade, X, Van Roy, F.
Two pathways of tumor necrosis factor signal transduction: In vitro and in vivo implications
In Tumor Necrosis Factor: Molecular and Cellular Biology and Clinical Relevance. (Fiers, W, Buurman, WA, eds.), Basel, Karger (Shugar, D, Rode, W, Borowski, E, eds.), Warszawa-Berlin, Polish Scientific Publishers PWN/Springer-Verlag, pp. 58-65, 1993. (Epub ---)

Schulze-Osthoff, K, Beyaert, R, Vandevoorde, V, Haegeman, G, Fiers, W.
Depletion of the mitochondrial electron transport abrogates the cytotoxic and gene-inductive effects of TNF
EMBO J 12, 3095-3104, 1993. (Epub ---)

Vanhaesebroeck, B, Reed, JC, De Valck, D, Grooten, J, Miyashita, T, Tanaka, S, Beyaert, R, Van Roy, F, Fiers, W.
Effect of bcl-2 proto-oncogene expression on cellular sensitivity to tumor necrosis factor-mediated cytotoxicity
Oncogene 8, 1075-1081, 1993. (Epub ---)

Beyaert, R, Fiers, W.
Potentiation of tumour necrosis factor-mediated activities by lithium salts: A review
Lithium 3, 181-189, 1992. (Epub ---)

Beyaert, R, Schulze-Osthoff, K, Van Roy, F, Fiers, W.
Synergistic induction of interleukin-6 by tumor necrosis factor and lithium chloride in mice: Possible role in the triggering and exacerbation of psoriasis by lithium treatment
Eur J Immunol 22, 2181-2184, 1992. (Epub ---)

Fiers, W, Beyaert, R, Brouckaert, P, Decoster, E, De Valck, D, Everaerdt, B, Grooten, J, Lenaerts, A, Libert, C, Schulze-Osthoff, K, Takahashi, N, Tavernier, J, Van Bladel, S, Van Dorpe, C, Vanhaesebroeck, B, Van Ostade, X, Van Roy, F.
Tumor necrosis factor: Mechanism of action at the molecular, cellular and in vivo level
In Tumor Necrosis Factor: Structure-function Relationship and Clinical Application. (Osawa, T, Bonavida, B, eds.), Basel, Karger, pp. 66-73, 1992. (Epub ---)

Fiers, W, Beyaert, R, Brouckaert, P, Decoster, E, De Valck, D, Everaerdt, B, Grooten, J, Lenaerts, A, Libert, C, Schulze-Osthoff, K, Takahashi, N, Van Bladel, S, Van Dorpe, C, Vanhaesebroeck, B, Van Ostade, X, Van Roy, F.
Tumor necrosis factor: Mechanism of action and its potential for anticancer therapy
In Molecular Aspects of Chemotherapy. , pp. 119-125, 1992. (Epub ---)

Schulze-Osthoff, K, Bakker, AC, Vanhaesebroeck, B, Beyaert, R, Jacob, WA, Fiers, W.
Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation
J Biol Chem 267, 5317-5323, 1992. (Epub ---)

Beyaert, R, De Potter, C, Vanhaesebroeck, B, Van Roy, F, Fiers, W.
Induction of inflammatory cell infiltration and necrosis in normal mouse skin by the combined treatment of tumor necrosis factor and lithium chloride
Am J Pathol 138, 727-739, 1991. (Epub ---)

Beyaert, R, Schulze-Osthoff, K, Van Roy, F, Fiers, W.
Lithium chloride potentiates tumor necrosis factor-induced and interleukin 1-induced cytokine and cytokine receptor expression
Cytokine 3, 284-291, 1991. (Epub ---)

Suffys, P, Beyaert, R, De Valck, D, Vanhaesebroeck, B, Van Roy, F, Fiers, W.
Tumour-necrosis-factor-mediated cytotoxicity is correlated with phospholipase-A2 activity, but not with arachidonic acid release per se
Eur J Biochem 195, 465-475, 1991. (Epub ---)

Vanhaesebroeck, B, Van Bladel, S, Lenaerts, A, Suffys, P, Beyaert, R, Lucas, R, Van Roy, F, Fiers, W.
Two discrete types of tumor necrosis factor-resistant cells derived from the same cell line
Cancer Res 51, 2469-2477, 1991. (Epub ---)

Beyaert, R, Suffys, P, Van Roy, F, Fiers, W.
Inhibition by glucocorticoids of tumor necrosis factor-mediated cytotoxicity. Evidence against lipocortin involvement
FEBS Lett 262, 93-96, 1990. (Epub ---)

Fiers, W, Beyaert, R, Brouckaert, P, Everaerdt, B, Haegeman, G, Libert, C, Suffys, P, Takahashi, N, Tavernier, J, Van Bladel, S, Vanhaesebroeck, B, Van Ostade, X, Van Roy, F.
In vitro and in vivo action of tumor necrosis factor
In Tumor Necrosis Factor: Structure, Mechanism of Action, Role in Disease and Therapy. (Bonavida, B, Granger, G, eds.), Basel, Karger, pp. 77-81, 1990. (Epub ---)

Fiers, W, Beyaert, R, Brouckaert, P, Everaerdt, B, Libert, C, Suffys, P, Takahashi, N, Vanhaesebroeck, B, Van Roy, F.
Mechanism of action of tumor necrosis factor and its implications for synergizing and antagonizing drugs
In Endotoxin From Pathophysiology to Therapeutic Approaches. (Baumgartner, J-D, Calandra, T, Carlet, J, eds.), Paris, Médecine-Sciences/Flammarion, pp. 59-68, 1990. (Epub ---)

Vanhaesebroeck, B, Cragoe Jr., EJ, Pouysségur, J, Beyaert, R, Van Roy, F, Fiers, W.
Cytotoxic activity of tumor necrosis factor is inhibited by amiloride derivatives without involvement of the Na+/H+ antiporter
FEBS Lett 261, 319-322, 1990. (Epub ---)

Van Roy, F, Mareel, M, Vleminckx, K, Beyaert, R, Fiers, W, Devleeschouwer, N, Muquardt, C, Legros, N, Bracke, M, Leclercq, G.
Hormone sensitivity in vitro and in vivo of v-ras-transfected MCF-7 cell derivatives
Int J Cancer 46, 522-532, 1990. (Epub ---)

Beyaert, R, Vanhaesebroeck, B, Suffys, P, Van Roy, F, Fiers, W.
Lithium chloride potentiates tumor necrosis factor-mediated cytotoxicity in vitro and in vivo
Proc Natl Acad Sci USA 86, 9494-9498, 1989. (Epub ---)

Fiers, W, Beyaert, R, Brouckaert, P, Everaerdt, B, Grooten, J, Haegeman, G, Libert, C, Suffys, P, Takahashi, N, Tavernier, J, Van Bladel, S, Vanhaesebroeck, B, Van Ostade, X, Van Roy, F.
Tumour necrosis factor and interleukin-6: Structure and mechanism of action of the molecular, cellular and in vivo level
In Vectors as Tools for the Study of Normal and Abnormal Growth and Differentiation. (Lother, H, Dernick, R, Ostertag, W, eds.), NATO ASI Series, Vol. H 34, Berlin, Springer-Verlag, pp. 229-240, 1989. (Epub ---)

Suffys, P, Beyaert, R, Van Roy, F, Fiers, W.
TNF in combination with interferon-gamma is cytotoxic to normal, untransformed mouse and rat embryo fibroblast-like cells
Anticancer Res 9, 167-172, 1989. (Epub ---)

Fiers, W, Beyaert, R, Brouckaert, P, Everaerdt, B, Haegeman, G, Suffys, P, Tavernier, J, Vanhaesebroeck, B, Van Roy, F.
TNF. Its potential as an antitumour agent
In Developments in Biological Standardization. (Gearing, AJH, Hennessen, W, eds.), Vol. 69, Basel, Karger, pp. 143-151, 1988. (Epub ---)

Suffys, P, Beyaert, R, Van Roy, F, Fiers, W.
Involvement of a serine protease in tumour-necrosis-factor-mediated cytotoxicity
Eur J Biochem 178, 257-265, 1988. (Epub ---)

Back to previous page

Export in CSV

Page 6 of 7
<< 1 - 2 - 3 - 4 - 5 - 6 - 7 >>

To top

What do these icons mean?

pdf file (800 kb)