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PhD defences

PhD defences are open to the public, and take place in the J. Schell seminar room of the UGent-VIB research building,  (unless otherwise specified).

Please check the IRC Calendar to know more about the upcoming PhD defences.

 

IRC Ph.D. theses since 2000

 Pdf-versions of the theses are available on the IRC intranet only (login required ).


  1. Xie Junhua (20-December-2022 ; R. Vandenbroucke, F. Haesebrouck & L. Van Hoecke)
    Studying the impact of the gastrointestinal bacteria on the brain, focusing on the blood-cerebrospinal fluid barrier and Alzheimer's disease
  2. Moon Sangphil (20-December-2022 ; M. Radwanska & S. Magez)
    Assessing impacts of experimental trypanosome infections on B cell memory
  3. Emmaneel Annelies (13-December-2022 ; Y. Saeys & S. Van Gassen)
    Improving diagnosis of primary immunodeficiencies using computational cytometry
  4. Tulkens Dieter (9-December-2022 ; K. Vleminckx & P. Van Vlierberghe)
    Uncovering novel cancer driver genes using CRISPR/Cas9 multiplexing in Xenopus tropicalis
  5. Heyndrickx Ines (25-November-2022 ; B. Lambrecht & H. Hammad)
    The role of protein crystals in type 2 immunity
  6. Iliaki Stella (26-October-2022 ; R. Beyaert & I. Afonina)
    Identification and functional characterization of CARD14 protein-protein interactions
  7. De Galan Cara (27-September-2022 ; D. Laukens & P. Hindryckx)
    New insights in the use of vedolizumab in inflammatory bowel disease
  8. Vetters Jessica (2-September-2022 ; S. Janssens)
    Novel pathways in NK cell biology
  9. Plehiers Nele (31-Augustus-2022 ; R. Vandenbroucke)
    Hijacking receptor-mediated transcytosis at the blood-cerebrospinal fluid barrier as delivery route for drugs to the brain
  10. Cappe Benjamin (7-July-2022 ; P. Vandenabeele & F. Riquet)
    Investigating the role of MLKL and EVs in cell-cell communication during necroptosis
  11. Pauwels Marie (28-June-2022 ; R. Vandenbroucke & L. Van Hoecke)
    Exploration of blood-cerebrospinal fluid barrier targeted extracellular vesicles as brain delivery strategy
  12. Jonckheere Sven (24-June-2022 ; G. Berx & S. Goossens)
    Therapeutic targeting of ZEB1-mediated EMT in metastatic colorectal cancer
  13. Remmerie Anneleen (13-June-2022 ; C. Scott & M. Guilliams)
    Understanding Hepatic Macrophage Phenotypes and Functions in Metabolic-Associated Fatty Liver Disease
  14. Kim Seo Woo (18-May-2022 ; R. Beyaert, J. Staal & A. Goossens)
    Unraveling the functional roles of endogenous phytohormones in mammals
  15. Holgado Muñoz Aurora (4-May-2022 ; R. Beyaert & I. Afonina)
    Targeting and regulation of interleukin-33 signalling in lung inflammation
  16. Van Coillie Samya (10-Dec-2021 ; P. Vandenabeele & T. Vanden Berghe)
    Therapeutic targeting of ferroptosis in experimental models of acute organ injury
  17. Delanghe Tom (10-Dec-2021 ; M.J. Bertrand & Y. Dondelinger)
    Unraveling the role of RIPK1 phosphorylation in TNF-mediated cell death and inflammation
  18. Vanderhaeghen Tineke (6-Dec-2021 ; C. Libert & R. Beyaert)
    The Effect of Hypoxia and Hypoxia Inducible Factors on the Glucocorticoid Receptor Function and their Role during Sepsis
  19. Srinivasan Sahana (3-Dec-2021 ; G. van Loo & M. Lamkanfi)
    Characterizing the role of microglial inflammation in neurodegeneration
  20. Oltean Teodora (30-Nov-2021 ; P. Vandenabeele, J. Maelfait & S. Adjemian Catani)
    Unraveling cell death modalities during influenza infection, vaccination, and cancer therapy
  21. Van Hove Lisette (19-Oct-2021 ; E. Hoste & G. van Loo)
    Unravelling molecular mechanisms mediating skin inflammation and tumour formation
  22. Fernandes Côrte-Real Beatriz (30-Sep-2021 ; M. Kleinewietfeld)
    The impact of high salt on Foxp3+ regulatory T cell metabolism and function
  23. Wiernicki Bartosz (27-Sep-2021 ; P. Vandenabeele, T. Vanden Berghe & K. Ravichandran)
    The role of lipid peroxidation in cell death and adaptive immune system regulation
  24. Vrancken Kurt (21-Sep-2021 ; P. Brouckaert & A. Blood)
    Plasma nitric oxide handling and its metabolism to endocrine S-nitrosothiol and nitrite: Role of ceruloplasmin and a novel function for postprandial triglyceride rich lipoproteins
  25. De Schutter Elke (8-Sep-2021 ; G. Van Camp, P. Vandenabeele & F. Riquet)
    Elucidation of the role of GSDME during apoptosis-driven secondary necrosis
  26. Percier-Lehebel Pauline (24-Aug-2021 ; W. Declercq, J. Grooten & O. Denis)
    Alternaria alternata and Aspergillus fumigatus mold species counteract experimental mycobacterial and allergic lung diseases through divergent innate immune mechanisms
  27. De Munck Steven (12-Jul-2021 ; S. Savvides)
    Structure and mechanism of cytokine mediated activation of ALK family receptor tyrosine kinases
  28. De Vos Tatjana (8-Jul-2021 ; S. Savvides)
    Structural basis for the activation and antagonism of the IL-9 signaling complex
  29. Loret Nele (08-Jun-2021 ; G. Berx, B. Lambrecht & P. Tummers)
    Cellular plasticity and heterogeneity in ovarian cancer progression and therapy resistance
  30. T'Jonck Wouter (28-Apr-2021 ; C. Scott)
    Notch-induced LXRα expression is essential for the maintenance of Kupffer cell identity
  31. Renson Thomas (15-Apr-2021 ; D. Elewaut, F. Van den Bosch & J. Dehoorne)
    Identifying pitfalls and opportunities of magnetic resonance imaging in spondyloarthritis
  32. Cloots Eva (12-Apr-2021 ; S. Janssens & S. Eyckerman)
    The ins and outs of IRE1B signaling: the role of IRE1B in mucosal homeostasis
  33. Vandewalle Jolien (24-Mar-2021 ; C. Libert & K. De Bosscher)
    The role of glucocorticoid resistance and TNFR1 signaling in sepsis
  34. Bosteels Cédric (26-Feb-2021 ; B. Lambrecht & H. Hammad)
    The role of DC subsets in respiratory viral infections and vaccination: a case of mistaken identity
  35. Vandendriessche Charysse (17-Dec-2020 ; R. Vandenbroucke & C. Van Cauwenberghe )
    Exploring the role of extracellular vesicles in Alzheimer’s and Parkinson’s disease
  36. Todorov Helena (16-Dec-2020 ; Y. Saeys & J. Marvel )
    Structure learning to unravel mechanisms of the immune system
  37. Dimitrakopoulou Dionysia (16-Oct-2020 ; K. Vleminckx & A. Willaert)
    CRISPR/Cas9 mediated modeling of TP53 and PTEN related malignancies in Xenopus tropicalis
  38. Gorlé Nina (19-Jun-2020 ; R. Vandenbroucke & F. Haesebrouck)
    Study of the importance of the choroid plexus in peripheral and brain inflammation
  39. Gilis Elisabeth (29-May-2020 ; D. Elewaut & S. Lambrecht)
    The role of MALT1 in rheumatic diseases
  40. Zuallaert Jasper (27-May-2020 ; W. De Neve, N. Callewaert & Y. Saeys)
    Automated learning of biologically relevant features from primary sequence using convolutional neural networks
  41. Priem Dario (22-Apr-2020 ; M. Bertrand)
    The ubiquitin-dependent regulation of the inflammatory response by A20 and MAGED1
  42. Van Wyngene Lise (19-Mar-2020 ; C. Libert & G. van Loo)
    The role of hepatic PPARa in sepsis and ZBTB32 in metabolic homeostasis
  43. Van Looveren Kelly (13-Mar-2020 ; C. Libert & K. De Bosscher)
    The glucocorticoid receptor in acute inflammation: new molecular insights and development of a new GR dimerization mutant
  44. Martens Arne (11-Feb-2020 ; G. van Loo)
    Mechanistic insights into the regulation of inflammatory pathology by A20
  45. Cannoodt Robrecht (16-Dec-2019 ; Y. Saeys & K. De Preter)
    Modelling single-cell dynamics with trajectories and gene regulatory networks
  46. Debeuf Nincy (13-Dec-2019 ; B. Lambrecht & S. Janssens)
    ORMDL3 in the regulation of sphingolipid synthesis and in the pathogenesis of allergic asthma
  47. Detry Sammy (9-Dec-2019 ; S. Savvides & Y. Bloch)
    Unraveling and targeting of molecular signaling mechanisms of IL-12 family, IL-18 and IL-33 cytokines using integrative structural biology
  48. Saelens Wouter (24-Oct-2019 ; Y. Saeys & B. Lambrecht)
    Developing and benchmarking methods for analysing transcriptomics data
  49. Brkic Marjana (27-Sep-2019 ; R. Vandenbroucke, S. Kanazir & C. Libert)
    Studies on structural and functional changes of mouse choroid plexus in the initiation of neuroinflammation
  50. Dubois Hanne (17-Sep-2019 ; A. Wullaert & M. Lamkanfi)
    Characterisation of innate immune responses associated with gastrointestinal norovirus infection
  51. Vanderkerken Matthias (16-Sep-2019 ; B. Lambrecht & T. Kerre)
    Molecular interactions controlling immune homeostasis in the marginal zone
  52. Bauwens Eva (3-Sep-2019 ; R. Vandenbroucke, F. Haesebrouck, A. Smet)
    Impact of gastric Helicobacter infections on the stomach-brain axis
  53. Martens Sofie (4-Jul-2019 ; P. Vandenabeele, V. Goossens, N. Takahashi)
    Necroptotic proteins in diseases: targeting RIP kinases in inflammatory disorders and exploring the role of MLKL in melanoma development
  54. Sabaghian Ehsan (1-Jul-2019 ; Y. van de Peer & Y. Saeys)
    Unravelling gene functions in Arabidopsis thaliana by means of network biology and machine learning
  55. Van Nuffel Elien (27-Jun-2019 ; R. Beyaert & I. Afonina)
    CARD14/MALT1 signaling in skin homeostasis and disease
  56. Naert Thomas (21-Jun-2019 ; K. Vleminckx)
    CRISPR/Cas9-mediated cancer modeling and identification of cancer cell vulnerabilities in Xenopus tropicalis
  57. Bolli Evangelia (19-Jun-2019 ; J. Van Ginderachter)
    Nanobody-mediated targeting of tumor-associated macrophages for cancer therapy
  58. Cambré Isabelle (4-Jun-2019 ; D. Elewaut & S. Lambrecht)
    Mechanical strain and its implications for mouse and human rheumatic diseases
  59. De Smedt Eva (23-May-2019 ; G. Berx)
    ZEB1 as 'jack-of-all-trades' in breast cancer progression
  60. Roels Joris (3-May-2019 ; Y. Saeys & W. Philips)
    Automated Segmentation of 3D Electron Microscopy Images
  61. Voet Sofie (15-Mar-2019 ; G. van Loo)
    Study of inflammatory signaling and microglia activation in central nervous system pathology
  62. Lork Marie Therese (8-Mar-2019 ; R. Beyaert, J. Staal)
    Molecular regulation of T cell receptor signaling
  63. Vandersarren Lana (27-Feb-2019 ; S. Janssens, B. Lambrecht)
    ER stress and T cell biology: IRE1 signaling and TAOK3 function
  64. Haspeslagh Eline (14-Feb-2019 ; H. Hammad, B. Lambrecht)
    Pulmonary immunomodulation of house dust mite-induced allergic asthma
  65. Pannecoucke Erwin (14-Feb-2019 ; S. Savvides)
    An integrative approach towards unraveling the activation of oncogenic FLT3
  66. Pauwels Anne-Marie (7-Jan-2019 ; R. Beyaert, Hoffmann E.)
    Impact of TLR4 engagement on the phagosomal proteome in dendritic cells and consequences for antigen degradation and presentation
  67. Mamantopoulos Michail (19-Dec-2018 ; A. Wullaert, M. Lamkanfi)
    Inflammasomes in intestinal host-microbe interactions
  68. Timmermans Steven (11-Dec-2018 ; C. Libert, Y. Saeys)
    Identifying and classifying protein coding gene polymorphisms between laboratory mouse strains and investigating glucocorticoid actions in sepsis models
  69. Souffriau Jolien (7-Dec-2018 ; C. Libert)
    Targeting TNF-induced acute inflammation by making use of SEDIGRAM or zinc
  70. Fulara Aleksandra (7-Dec-2018 ; S. Savvides)
    Study of the GspLM complex, an inner membrane component of the type II secretion system from Pseudomonas aeruginosa
  71. Vluymans Sarah (29-June-2018 ; Y. Saeys, C. Cornelis)
    Dealing with Imbalanced and Weakly Labelled Data in Machine Learning using Fuzzy and Rough Set Methods
  72. Godar Marie (29-June-2018 ; B. Lambrecht, C. Blanchetot)
    Development of Novel Multifunctional Antibodies to Treat Asthma
  73. Saavedra Pedro H. V. (26-June-2018 ; A. Wullaert, M. Lamkanfi)
    Mechanism and functions of the cytosolic receptor Pyrin
  74. Moraes de Vasconcelos Nathalia (26-June-2018 ; A. Wullaert, M. Lamkanfi)
    Cell death signaling at the crossroads of inflammasome activation
  75. Slowicka Karolina (21-June-2018 ; G. van Loo, L. Vereecke)
    Study of intestinal homeostasis and pathology through mouse gene targeting
  76. Soen Bieke (30-May-2018 ; G. Berx)
    Zeb1 and Zeb2: master regulators of mononuclear phagocyte development and homeostasis
  77. De Keuckelaere Evi (22-May-2018 ; F. Van Roy, G. Berx)
    The role of Nanos3 in tumor progression
  78. Kip Elodie (9-May-2018 ; R. Beyaert, S. De Gucht)
    Impact of the paracaspase MALT1 on rabies virus-induced neuroinflammation and disease
  79. Sundararaman Srividhya (26-Apr-2018 ; F. Van Roy, K. Vleminckx)
    Cadherin repertoires in lower metazoans - Trichoplax adhaerens and Nematostella vectensis
  80. Bloch Yehudi (16-Apr-2018 ; S. Savvides, K. Verstraete)
    Structure, mechanism, and antagonism of the pro-inflammatory receptor complex mediated by interleukin-23
  81. Carron Philippe (30-Mar-2018 ; D. Elewaut, F. Van den Bosch)
    New Imaging modalities and treatment strategies in Spondyloarthritis
  82. Delvaeye Tinneke (9-Mar-2018 ; P. Vandenabeele, D. Krysko, L. Leybaert)
    The pathological role of Cx43 and MLKL in TNF-induced Systemic Inflammatory Response Syndrome
  83. Noelanders Rivka (1-Mar-2018 ; K. Vleminckx)
    Wnt/beta-catenin signaling in the Xenopus hindbrain: development and cancer
  84. Tanghe Giel (23-Feb-2018 ; W. Declercq)
    Mechanistic insights into the regulation of RIPK4 and its function in skin homeostasis and pathology
  85. Berings Margot (21-Feb-2018 ; M. Dullaers, P. Gevaert, B. Lambrecht)
    House dust mite allergic rhinitis: A novel take on diagnosis and treatment
  86. Varkas Gaëlle (20-Feb-2018 ; D. Elewaut, F. Van den Bosch)
    Axial spondyloarthritis: New insights in diagnosis and patient stratification
  87. D'hondt Sanne (15-Dec-2017 ; F. Malfait, S. Janssens & M. Bertrand)
    Type III collagen, a major fibrillar collagen with major issues
  88. Dendoncker Karen (13-Oct-2017 ; C. Libert)
    Elucidating the mechanism behind TNF-induced glucocorticoid resistance and strategies to overcome this resistance
  89. Steeland Sophie (5-Oct-2017 ; C. Libert & R. Vandenbroucke)
    Therapeutic targeting of inflammatory mediators in sepsis and neurodegenerative diseases
  90. Favreau Mérédis (4-Oct-2017 ; D. Elewaut, K. Venken, E. Menu & K. Vanderkerken)
    Immune therapy in multiple myeloma: Can iNKT cells be targeted?
  91. Abels Chloé (26-Sep-2017 ; J. Van Ginderachter, P. De Baetselier & A. Beschin)
    Unravelling the role of liver associated myeloid cells in sterile inflammation and infection
  92. De Wilde Katelijne (20-Sep-2017 ; D. Elewaut & S. Lambrecht)
    Novel myeloid regulators of rheumatic diseases
  93. Bogaert Delfien (4-Sep-2017 ; M. Dullaers, F. Haerynck & E. De Baere)
    Molecular diagnosis of Common Variable Immunodeficiency and related antibody disorders: an integrated immunological and genetic approach
  94. Van der Borght Katrien (7-Jul-2017 ; B. Lambrecht)
    Cardiac dendritic cells activate autoreactive T cells in the healthy and diseased heart
  95. Deckers Julie (5-Jul-2017 ; H. Hammad & K. De Bosscher)
    The skin as a central player in house dust mite allergy
  96. Aaes Tania Love (5-Jul-2017 ; P. Vandenabeele & D. Krysko)
    The impact of cell death modalities on the immunogenicity of cancer cells
  97. Vandamme Niels (26-Jun-2017 ; G. Berx)
    ZEB1 and ZEB2 dictate melanocyte homeostasis and melanoma phenotype switching
  98. Ruyssinck Joerie (19-Jun-2017 ; Y. Saeys & T. Dhaene)
    Machine Learning for Biological Network Inference
  99. Krols Michiel (13-Jun-2017 ; S. Janssens & V. Timmerman)
    Mutations in Atlastin-3: implications for ER membrane fusion and crosstalk with mitochondria
  100. Le Cann Fabienne (2-Jun-2017 ; P. Vandenabeele)
    Characterization of new necroptosis innhibitors targeting RIPK1
  101. Udhayakumar Vimal Kumar (24-May-2017 ; J. Grooten & S. De Koker)
    Development and validation of synthetic-virus like vaccines
  102. Van Gassen Sofie (23-May-2017 ; Y. Saeys & T. Dhaene)
    Development of Machine learning techniques for flow cytometry data
  103. Govindarajan Srinath (16-May-2017 ; D. Elewaut & M. Drennan)
    Mechanistic insights into the regulation of iNKT development and cytokine production
  104. Schuijs Martijn (14-Apr-2017 ; H. Hammad and B. Lambrecht)
    The Pathogenesis of House Dust Mite-driven Asthma: From Barn to Bedside
  105. Ladik Maria (4-Apr-2017 ; P. Vandenabeele)
    Development of biosensing systems to monitor necroptosis
  106. Van Nieuwenhuysen Tom (31-Mar-2017 ; K. Vleminckx)
    Modeling human disease in Xenopus tropicalis using programmable nucleases
  107. Urwyler-Rösselet Corinne (17-Mar-2017 ; W. Declercq & P. Vandenabeele)
    Study of the functions of RIPK4 in epidermal development and signal transduction
  108. Balusu Sriram (15-Mar-2017 ; R. Vandenbroucke & C. Libert & K. Gevaert)
    Novel insights into the choroid plexus response to systemic inflammation and Alzheimer's disease
  109. Vermeulen Ilke (3-Mar-2017 ; J. Grooten)
    Tuberculosis: how different synthetic analogues of pathogen associated mycolates affect lipid homeostasis of murine host macrophages
  110. Catrysse Leen (24-Feb-2017 ; G. van Loo & R. Beyaert)
    Diabetes and inflammation, how A20 regulates tissue homeostasis in metabolic tissues
  111. Sichien Dorine (24-Feb-2017 ; B. Lambrecht & M. Guilliams)
    Differential requirement for IRF8 in the development and function of monocytes and dendritic cells
  112. Tavernier Simon (31-Jan-2017 ; B. Lambrecht & S. Janssens)
    Dendritic cells under stress: on the role of the unfolded protein response and hypoxia signalling
  113. Cypers Heleen (23-Jan-2017 ; D. Elewaut)
    The role of intestinal inflammation in initiation, monitoring and outcome of spondyloarthritis
  114. De Beuckelaer Ans (23-Dec-2016 ;J. Grooten)
    mRNA-based vaccines to elicit CD8 T cell immunity
  115. Borghi Alice (22-Dec-2016 ;R. Beyaert)
    New insight into the ubiquitin-mediated regulation of TNFR2 signaling
  116. Hassannia Behrouz (22-Dec-2016 ;P. Vandenabeele)
    Ferroptosis: triggers, inhibitors and therapeutic potential in neuroblastoma
  117. Van Putte Wouter (19-Dec-2016 ;S. Savvides)
    The type II secretion system and membrane vesiculation: bacterial secretion systems as a target for anti-virulence drug development
  118. Meloni Laura (8-Dec-2016 ;R. Beyaert)
    Molecular mechanisms of mechanotransdcution and osteoclastogenesis in arthritis
  119. Gül Ismail Sahin (6-Dec-2016 ;F. Van Roy)
    Molecular evolution of the armadillo repeat superfamily and characterization of representative members in key model organisms
  120. Demeestere Delphine (2-Dec-2016 ;C. Libert & R. Vandenbroucke)
    A study of inflammatory mechanisms involved in systemic inflammation and brain trauma
  121. Ballegeer Marlies (2-Dec-2016 ;C. Libert & R. Vandenbroucke)
    Study of the role and regulation of Glucocorticoid induced leucine zipper (GILZ) and GR dimers in acute inflammation
  122. Neyt Katrijn (21-Oct-2016 ;B. Lambrecht & M. Guilliams)
    Pulmonary immune responses against influenza A virus infection
  123. Jimenez Fernandez Daniel (22-Sep-2016 ;L. Lamkanfi & K. Gevaert)
    Functional characterization of inflammatory caspases
  124. Billi Eleonora (22-Sep-2016 ; F. Van Roy & J. Tavernier)
    Identification and functional analysis of molecular interaction partners of δ-protocadherin family members with putative roles in cancer
  125. Sips Magdalena (31-Aug-2016 ; P. Brouckaert)
    Harnessing innate immunity to prevent and control HIV infection
  126. Demeyer Annelies (28-Jun-2016 ; R. Beyaert)
    Functional characterization of the paracaspase MALT1 in T cells
  127. Grootjans Sasker (15-Apr-2016 ; P. Vandenabeele)
    Identification of potential RIPK1 substrates during Necroptosis
  128. Aguileta Miguel (15-Apr-2016 ; M. Bertrand & P. Vandenabeele)
    Characterization of new proteins involved in apoptosis regulation
  129. Juchtmans Nele (22-Mar-2016 ; D. Elewaut)
    The role of stress related proteins in osteoarthritis
  130. Félix Jan (7-Jan-2016 ; S. Savvides)
    Structural Principles of binding duality in cognate and viral cytokine receptors
  131. Petta Ioanna (4-Dec-2015 ; C. Libert & J. Tavernier)
    Identification of striatin-3 and ZBTB32 as two novel modulators of glucocorticoid receptor activity
  132. Sipieter François (3-Dec-2015 ; F. Riquet, P. Vandenabeele, K. Cailliau-Maggio & L. Héliot)
    Development and validation of kinase activity reporters for the dynamical study of cell response modalities by microscopy ~ Role of the kinase MAPK/ERK in necroptosis.
  133. Deng Lei (3-Dec-2015 ; X. Saelens)
    Targeted prokaryotic delivery of a conserved influenza A virus epitope for oral vaccination
  134. Santens Francis (25-Sep-2015 ; N. Callewaert)
    Engineering of protein production systems to drastically reduce glycan heterogeneity of biopharmaceuticals
  135. Claes Katrien (11-Sep-2015 ; N. Callewaert)
    Development of modular engineering tools for membrane protein expression in yeast
  136. Dondelinger Yves (3-Jul-2015 ; P. Vandenabeele & M. Bertrand)
    Unraveling the molecular mechanisms of RIPK1-mediated cell death
  137. Vandewalle Kristof (19-Jun-2015 ; N. Callewaert)
    Building genome-wide mutant resources in slow-growing mycobacteria
  138. De Visscher Charlotte (20-Feb-2015 ; N. Callewaert)
    Engineering of the production of mannose-6-phosphate-modified lysosomal enzymes by the yeast Pichia pastoris
  139. Elton Lynn (19-Dec-2014 ; R. Beyaert)
    Identification and functional characterization of novel MALT1 substrates
  140. Smet Muriel (18-Dec-2014 ; J. Grooten)
    Cholesterol-sensing liver X receptors and mycolic acid bio-lipids at the crossroads of lipid metabolism and inflammation
  141. Mueller Christina (16-Dec-2014 ; R. Beyaert)
    Molecular and functional characterization of interleukin-33 signaling
  142. Volckaert Thomas (8-Dec-2014 ; R. Beyaert)
    Epithelial-mesenchymal crosstalk during lung development and regeneration
  143. Grine Lynda(25-Nov-2014 ; C. Libert)
    Study of the role of type I Interferons in TNF-mediated inflammation.
  144. Tyberghein Koen (30-Sep-2014 ; F. Van Roy)
    Alpha-catenins: protein replacement as a strategy against cancer invasion and metastasis?
  145. Ydens Elke (24-Apr-2014 ; S. Janssens & V. Timmerman)
    Activation of the innate immune response during peripheral nerve degeneration: from pattern recognition receptors to immune effector cells
  146. Broos Stefan (24-Jan-2014 ; F. Van Roy & P. De Bleser)
    Developing algorithms for the in silico identification of transcription factor binding sites
  147. Vandendriessche Benjamin (13-dec-2013 ; P. Brouckaert & A. Cauwels)
    Complex dynamics in systemic inflammation: quantification of coupling and targeting of the nitric oxide-soluble guanylate cyclase axis
  148. Pollard Charlotte (6-dec-2013 ; J. Grooten & S. De Koker)
    Evaluation of CD8+ T cell responses upon mRNA vaccination and the implication of type I IFN signaling
  149. Puimège Leen (29-nov-2013 ; C. Libert)
    A molecular genetic analysis of TNFR1 regulation in SPRET/EI and generation of new TNFR1 inhibitory tools
  150. Vandevyver Sofie (22-nov-2013 ; C. Libert)
    Study of the molecular mechanisms of glucocorticoid receptor function and resistance in TNF-induced toxicity
  151. Plantinga Maud (16-Oct-2013 ; Bart Lambrecht)
    The role of dendritic cell subsets in allergic sensitization
  152. Ayiseh Rene B. (19-Sep-2013 ; P. Vandenabeele)
    Role of cell death and caspases in intestinal inflammation
  153. Kaczmarek Agnieszka (4-Jul-2013 ; P. Vandenabeele)
    Sensing of apoptotic and necroptotic cell death by the innate immune system
  154. Willart Monique (27-Jun-2013 ; B. Lambrecht)
    Immune activation at the lung epithelial barrier
  155. McGuire Conor (31-May-2013 ; G. van Loo & R. Beyaert)
    The study of signaling pathways controlling central nervous system inflammation and pathology
  156. De Baets Sarah (10-Apr-2013 ; X. Saelens)
    Novel vaccination strategies against human repiratory syncytial virus
  157. Pringels Sarah (17-Apr-2013 ; J. Grooten)
    Screening of the Vascular Endothelial Growth Factor family in human colon cancer
  158. Cardoso Francisco Miguel Lopez (28-Feb-2013 ; X. Saelens)
    Antiviral activity of camelid single domain antibodies targeting the neuraminidase of H5N1 Influenza virus
  159. De Groote Philippe (21-dec-2012 ; W. Declercq)
    Study of RIPK4 function in skin homeostatsis and disease
  160. Devos Michael (21-dec-2012 ; W. Declercq)
    Study on the role of delatNp63alpha and caspase-14 in skin homeostasis and pathology
  161. Kahr Irene (20-dec-2012 ; F. Van Roy)
    Functional analysis of the candidate tumor suppressor protein protocadherin-10
  162. Verhelst Judith (19-dec-2012 ; X. Saelens)
    Unraveling the antiviral mechanism of mouse Mx1 directed against influenza A
  163. Janssens Sylvie (19-Oct-2012 ; K. Vleminckx)
    Identification of novel target genes of the Wnt/β-catenin pathway during Xenopus development and analysis of their epigenetic regulation
  164. Haenebalcke Lieven (5-Oct-2012 ; J. Haigh)
    Generation and use of novel ROSA26-based ESC/iPSC technologies to study cellular reprogramming and gene function during lineage-directed differentiation
  165. Naessens Thomas (6-Jul-2012 ; J. Grooten)
    Functional dynamics of resident alveolar macrophages in a mouse model of allergic asthma
  166. Vander Beken Seppe (6-Jul-2012 ; J. Grooten)
    Mycobacterium tuberculosis bio-lipid mycolic acid and mammalian cholesterol-sensor liver X-receptor in airway immunity
  167. Farhang Ghahremani Morvarid (5-Jul-2012 ; J. Haigh)
    Molecular and genetic interplay between p53 and VEGF in tumour angiogenesis
  168. Meuris Leander (2-Jul-2012 ; N. Callewaert)
    GlycoDelete: a new glycoengineering concept for protein production in mammalian cells
  169. Nittner David (8-Jun-2012 ; J.C. Marine)
    Role of the microRNA pathway in retinoblastoma
  170. Guerfal Mouna (8-May-2012 ; N. Callewaert)
    Yeast secretory system engineering for enhanced membrane protein expression
  171. Roose Kenny (26-Jan-2012 ; X. Saelens)
    Design and validation of novel broad influenza B vaccine
  172. Andries Vanessa (26-Jan-2012 ; F. Van Roy)
    Functional analysis of the NBPF1 gene in cancer
  173. Bekaert Tine (20-Jan-2012 ; R. Beyaert)
    Functional characterization of the paracaspase MALT1
  174. Gembarska Agnieszka (19-Jan-2012 ; J.C. Marine)
    MDMX is a key therapeutic target in skin melanoma
  175. Schotsaert Michael (16-Dec-2011 ; X. Saelens)
    Modulation of humoral and cellular immunity to influenza by vaccination
  176. Zwolinska Aleksandra (15-Dec-2011 ; J.C. Marine)
    Study of three putative nuclear modulators of the p53 pathway
  177. Fransen Mathias (9-Dec-2011 ; K. Vleminckx)
    Exploring the role of caspases and RIPK4 during Xenopus development
  178. Van Hauwermeiren Filip (25-Nov-2011 ; C. Libert)
    New strategies to prevent TNF-induced toxicity in TNF/IFNgamma-based anti-tumor models
  179. Gheldof Alexander (21-Oct-2011 ; G. Berx)
    Functional analysis of the EMT inducing transcription factor ZEB1 during malignant carcinoma progression
  180. Duprez Linde (14-Oct-2011 ; P. Vandenabeele)
    Role of RIP1 in TNF-induced cell death in vitro and in vivo
  181. Tatari Marianthi (26-Sep-2011 ; G. Berx)
    In vivo analysis of the role of ZEB2 in epithelial homeostasis and tumor progression
  182. Pinheiro Iris (8-Jul-2011; C. Libert)
    Molecular cloning of the X-chromosome located LPS-resistance gene of SPRET/Ei mice
  183. Maelfait Jonathan (8-Jul-2011; R. Beyaert)
    Signaling in antiviral immunity and its regulation by the ubiquitin-editing protein A20
  184. Lambertz Irina (6-Jul-2011; J.C. Marine)
    MicroRNA control of cancer development
  185. Vanlangenakker Nele (1-Jul-2011; P. Vandenabeele)
    Unraveling TNF-induced necrotic signaling pathways using RNA interference and live-cell imaging
  186. Quimbaya Mauricio (23-Jun-2011; L. De Veylder & G. Berx)
    Identification of novel conserved cell cycle genes through data integration and comparative genomics between plants and humans
  187. Verhelst Kelly (17-Jun-2011; R. Beyaert)
    Molecular analysis of the ubiquitin-editing protein A20
  188. Vereecke Lars (27-May-2011; R. Beyaert)
    Controlling inflammation and cell death at the intestinal epithelial interface and beyond: Lessons from conditional 120 knockout mice
  189. De Pourcq Karen (27-May-2011; N. Callewaert)
    Glycosylation engineering in the yeast Yarrowia lipolytica: creating an expression system to produce complete homogeneous glycoproteins
  190. Wirawan Ellen (8-Apr-2011; P. Vandenabeele)
    Molecular interplay between autophagy and apoptosis through caspase-mediated cleavage of Beclin-1
  191. Kersse Kristof (8-Apr-2011; P. Vandenabeele)
    Inflammasome modulation and NF-kB activation by caspase-1-related CARD domains
  192. Dejonckheere Eline (1-Apr-2011; C. Libert)
    The role of matrix metalloproteinase 8 in TLR4-mediated acute systemic inflammation
  193. Pieters Tim (25-Feb-2011; F. Van Roy)
    Functional analysis of mice harboring a knock-out or knock-in of the alternatively spliced exon C of p120ctn
  194. Hooghe Bart (25-Feb-2011; F. Van Roy)
    In silico approaches to studying transcriptional gene regulation: prediction of transcription factor binding sites and applications thereof
  195. De Clercq Sarah (5-Jul-2010; J.-C. Marine)
    Study of the physiological and oncogenic properties of Mdm2 and Mdm4
  196. Van Bogaert Tom (1-Jul-2010; C. Libert)
    Study of the molecular mechanism of glucucorticoid resistance in tumor necrosis factor-induced systemic inflammation
  197. Galle Marlies (1-Jul-2010; R. Beyaert)
    Modulation of macrophage immune responses by the Pseudomonas aeruginosa type three secretion system
  198. Hoste Esther (24-Jun-2010; W. Declercq & P. Vandenabeele)
    Study of the role of caspase-14 in epidermal cornification
  199. Lefever Tine (3-Jun-2010; F. Van Roy)
    Analysis of N-WASP function in keratinocytes in vivo
  200. Vanderschaeghe Dieter (1-Jun-2010; J. De Langhe & N. Callewaert)
    GlycoHepatoTest: validation and analytical technology development for implementation on microfluidics analyzer
  201. Dejager Lien (30-Apr-2010; C. Libert)
    Molecular and genetic analysis of the resistance of the mouse strain SPRET/Ei to endotoxemia and Gram-negative sepsis
  202. Houthuys Erica (2-Apr-2010; P. Brouckaert)
    Transcriptome analysis of monocytes and macrophages in mycobacterial infection and chronic kidney disease
  203. Thoonen Robrecht (26-Feb-2010; P. Brouckaert)
    Generation and characterization of apo-soluble Guanylate Cyclase mice
  204. Vanhooren Valerie (27-Nov-2009; C. Libert)
    Glycomics of mammalian aging
  205. Crabbe Ellen (20-Nov-2009; K. Vleminckx)
    Identification and functional characterization of novel N-cadherin interacting proteins
  206. Willemarck Nicolas (20-Nov-2009; K. Vleminckx)
    Het Xenopus embryo als experimenteel platform voor de exploratie van nieuwe functies voor caspasen en tumorgeassocieerde de novo lipogenese
  207. Schoonooghe Steve (19-Oct-2009; J. Grooten)
    Multivalent and cross-reactive bispecific bibodies and tribodies for enhanced MUC1 tumour targeting
  208. Vanlaere Ineke (24-Sep-2009; C. Libert)
    Role of MMP-7 and IL-17A in acute systemic inflammation
  209. Demon Dieter (22-Jun-2009; P. Vandenabeele)
    Caspase-7: protease specificity activation and construction of a conditional knockout
  210. Tran Hong Thi (19-Jun-2009; K. Vleminckx)
    Development and use of novel transgenic lines to study Wnt signaling in the Xenopus embryo
  211. Huang Lieven (7-Jan-2009; R. Beyaert/P. De Baetselier)
    Characterization of EGF receptor targeting Nanobodies and ABIN for the treatment of EGF receptor-dependent tumours
  212. De Koker Stefaan (28-Oct-2008; N. Mertens/J. Grooten)
    Polyelectrolyte microcapsules for antibody delivery
  213. Huyghe Leander (10-Oct-2008; P. Brouckaert)
    Study of molecular and immunological factors that determine the sensitivity to the antitumor effect of Tumor Necrosis factor
  214. Bogaert Pieter (27-Mar-2008; J. Grooten)
    Transcriptome profiling of macrophage activation and inflammatory mediator expression in experimental mouse models of allergic pulmonary inflammation
  215. Jacobs Pieter (29-Feb-2008; N. Callewaert)
    Glycosylation and cell surface engineering in Pichia pastoris
  216. Vandewalle Cindy (28-Feb-2008; G.Berx & F. Van Roy)
    The role and mechanisms of SIP1 in the dedifferentiation of epithelial cancers
  217. Beekman Chantal - (21-Jan-2008; J.-C. Marine & F. Van Roy)
    A study of three putative players in the p53 pathway: Nucleostemin, Ptprv and TCTP
  218. Verschuere Veerle - (20-Dec-2007; K. Vleminckx)
    Analysis of the role of the p120 catenin subfamily in cell adhesion and cell migration during the early development of Xenopus laevis
  219. Loos Michaela - (7-Dec-2007; E. Remaut)
    Modulation of dendritic cell function through delivery of effector proteins by genetically modified Lactococcus lactis
  220. Coornaert Beatrice - (30-Nov-2007; R. Beyaert)
    MALT1 paracaspase-mediated regulation of the NF-kappaB inhibitory protein A20 in antigen receptor signaling
  221. Van Huynegem Karolien - (23-Nov-2007; E. Remaut)
    Genetically modified Lactococcus lactis as a tool in the prevention and healing of chemotherapy-induced intestinal mucositis
  222. Ovaere Petra - (5-Oct-2007; P. Vandenabeele)
    Identification of a Caspase-14 activating protease in murine skin extracts
  223. Verstrepen Lynn - (5-Oct-2007; R. Beyaert)
    Functional characterization of ABIN-3 and TAX1BP1 as negative regulators of NF-kappaB signaling
  224. Vande Walle Lieselotte - (28-Sep-2007; P. Vandenabeele)
    Role of the mitohondrial serine protease HtrA2/Omi in apoptosis
  225. Sips Patrick  (6-Jul-2007; P. Brouckaert)
    Functional analysis of soluble guanylate cyclase isoforms using mouse transgenics: cardiovascular effects of targeted mutagenesis of the alpha 1 subunit
  226. Vercammen Elisabeth  (22-Jun-2007; R. Beyaert)
    The secret life of Interleukin-1beta: molecular mechanisms involved in its production and biological activities
  227. Goethals An  (11-May-2007; P. Brouckaert)
    Studie in muismodellen van de mechanismen verantwoordelijk voor het antitumoraal effect van Tumor Necrosis Factor
  228. Van Lint Philippe  (20-apr-07, 16h30; C. Libert)
    The role of matrix metalloproteinases in specific inflammatory disorders
  229. Van Roy Maarten  (20-apr-07, 14h00;  C. Libert)
    New strategies to improve the safety and efficacy of a TNF/IFNgamma-based antitumor therapy
  230. Schepens Bert  (6-Oct-2006; R. Beyaert)
    The great escape: how Internal Ribosome Entry Sites can initiate translation of crucial mRNAs during hypoxia and mitosis
  231. De Smet Kris  (29-Sep-2006; R. Contreras)
    Studie van het celdoodproces in Candida albicans
  232. Schauvliege Reinout  (29-Sep-2006; R. Beyaert)
    Molecular mechanisms of LPS-induced pro-inflammatory signalling
  233. Delvaye Mieke  (28-Sep-2006; F. Van Roy & K. Vleminckx)
    Analysis of the morphogenetic role of known and novel cadherin-interacting proteins in Xenopus laevis
  234. Festjens Nele  (7-Jul-2006; P. Vandenabeele & X. Saelens)
    Characterization of molecular mechanisms associated with and involved in necrotic cell death
  235. Krysko Dmitri  (5-Jul-2006; K. D'Herde & P. Vandenabeele)
    Cell death: Initiation, propagation and clearance
  236. Laukens Debby  (29-Jun-2006; E. Remaut & P. Rottiers)
    Transcriptome profiling and genetic analysis to identify and characterize susceptibility genes for Crohn's disease
  237. Wullaert Andy  (5-May-2006; R. Beyaert)
    Effect of ABINs on intracellular signaling pathways involved in TNF-mediated liver injury
  238. Mahieu Tina  (31-Mrch-2006; C. Libert)
    A molecular analysis of the LPS resistance of the mouse species /Mus spretus
  239. Bultinck Jennyfer  (16-Mrch-06; P. Brouckaert)
    (Sub)cellular expression patterns and pathophysiological significance of INOS in inflammatory shock
  240. Goossens Steven  (24-Feb-06; F. Van Roy)
    Functional analysis of mouse alpha T-catenin
  241. Heirman Ingeborg  (1-Feb-06; J. Grooten)
    The tumor cell oxidative status and its interaction with eicosanoid synthesis in the control of tumor growth and malignant progression
  242. Vandepoele Karl  (22-Dec-2005; F. Van Roy)
    Genomic characterization and functional analysis of the novel NBPF gene family
  243. Termont Sofie  (16-Dec-2005; E. Remaut & P. Rottiers) 
    Optimization of Lactococcus lactis mediated mucosal delivery of cytokines
  244. Ryckaert Stefan  (9-Dec-2005; R. Contreras)
    Ontwikkeling van nieuwe toepassingen voor gist oppervlakte-expressie
  245. Soubry Adelheid  (6-Dec-2005; F. Van Roy)
    Analyse van de transcriptionele repressor Kaiso in humane tumoren en tijdens de celcyclus
  246. Denayer Tinneke  (2-Dec-05; F. Van Roy & K. Vleminckx)
    Functional study of the canonical Wnt pathway using transgenic tools in Xenopus laevis
  247. De Craene Bram  (19-may-05; F. Van Roy & G. Berx)
    The role of the Snail family of transcription factors in epithelial-mesenchymal transitions
  248. Van Belle Tom  (25-mar-05; J. Grooten)
    IL-15, a cytokine with direct action on CD8+ T cells, exerts an indirect action on TCR-stimulated CD4+ T cells
  249. Vanden Berghe Tom  (18-feb-05; P. Vandenabeele)
    Molecular interplay between apoptotic and necrotic cell death pathways
  250. Willems An   (28-jan-05; N. Mertens & J. Grooten)
    Tumorafhankelijke T cel activering met bispecifieke antilichamen: optimalisatie door protein-design
  251. Brouckaert Greet  (27-jan-05; P. Vandenabeele)
    Analysis of a cellular model for the recognition and phagocytosis of apoptotic and necrotic cells by macrophages
  252. Lamkanfi Mohamed  (10-nov-04; P. Vandenabeele)
    CARD proteins in apoptosis and inflammation
  253. Reekmans Rieka  (23-sep-04; R. Contreras)
    Transcriptional profiling of the Bax-responsive genes in S. cerevisiae.
  254. Vandenbroucke Klaas  (10-sep-04; E. Remaut, L. Steidler & P. Rottiers)
    Genetically modified Lactococcus lactis as in vivo delivery system for trefoil factors at the intestinal mucosa.
  255. Geysens Steven  (28-jun-04; R. Contreras)
    Klonering en karakterisering van fungale genen betrokken bij eiwit N-glycosylatie, kwaliteitscontrole en secretie.
  256. Vervecken Wouter  (28-jun-04; R. Contreras)
    Modificatie van de N-glycosylatiesyntheseweg van Aspergillus niger en Pichia pastoris.
  257. van Gurp Marjan (25-jun-04; P. Vandenabeele)
    Identification of protein-protein interactions in cell death signalling using the yeast two-hybrid system
  258. Staelens Jan  (31-mrt-04; C Libert)
    A molecular genetic analysis of the TNF resistance of the mouse species Mus spretus
  259. Bogaerts Sven  (13-feb-04; F. Van Roy)
    Characterization of a novel zinc finger protein ANC_2H01 (ZASC1)
  260. Pynaert Gwenda  (21-nov-03; J. Grooten)
    De regulerende werking van macrofagen op luchtweginflammatie in een muismodel voor astma 
  261. Vanpoucke Griet  (26-sep-03; F. Van Roy & G. Berx)
    The human alpha-catenins : regulation mechanisms controlling their expression
  262. Comijn Joke  (26-sep-03; F. Van Roy & G. Berx)
    SIP1-mediated transcriptional regulation of E-cadherin and identification of new SIP1 target genes
  263. Lippens Saskia  (12-sep-03; P. Vandenabeele & W. Declercq)
    Expression, regulation and processing of caspase-14 during epidermal differentiation
  264. Vanhalst Koen  (29-aug-03; F. Van Roy)
    Identification and functional analysis of new cadherin genes, possibly involved in murine brain development
  265. Buys Emmanuel  (23-may-03; P. Brouckaert)
    Target validation od soluble guanylate cyclase using conditional targeted mutagenesis in mice
  266. Carpentier Isabelle  (9-may-03; R. Beyaert)
    Molecular and functional characterization of the tumor necrosis factor receptor associated proteins TRAF1 and TRAF2
  267. Hostens Jeroen  (24-apr-03; P. Brouckaert)
    Onderzoek naar het mechanisme van de versterkende werking van IFN-gamma op het anti-tumoraal effect van TNF
  268. Janssens Sophie  (21-febr-03; R. Beyaert)
    Regulation of Interleukin-1 and endotoxin-induced responses by alternative splicing of MyD88
  269. Van Oekelen Dirk  (28-juni-02; G. Haegeman)
    The 5-HT2 receptor family: atypical regulation and functional insight through altered gene expression using antisense
  270. van Loo Geert  (14-juni-02; P. Vandenabeele)
    Apoptotic and necrotic cell death: cell death domain proteins and release of mitochondrial factors
  271. Strumane Kristin  (14-juni-02; F. Van Roy)
    E-cadherin-dependent differential gene expression in cancer cells reveals the novel E-cadherin-repressed oncogene hECRep1
  272. Callewaert Nico  (31-mei-02; R. Contreras) 
    Protein N-glycosylation : from yeast to man
  273. Vermeulen Linda  (17-mei-02; G. Haegeman)
    Studie van het moleculair mechanisme voor transcriptionele activering van NF- B p65 na inflammatorische stimulatie
  274. Bonné Stefan  (30-apr-02; F. Van Roy)
    Klonering en functionele karakterisering van het desmosomale eiwit plakophiline-3
  275. Janssens Barbara  (29-mrt-02; F. Van Roy)
    Study of two novel members of the human alpha-catenin family
  276. Wielockx Ben  (29-mrt-02; C. Libert & P. Brouckaert)
    De rol van proteasen en de identificatie van genen, coderend voor beschermende eiwitten, in TNF-geïnduceerde hepatitis en letale shock
  277. Hochepied Tino  (21-sep-01; P.Brouckaert & C.Libert)
    Onderzoek naar de rol van acute-fase proteïnen, in het bijzonder alfa1-zuur glycoproteïne, in muismodellen voor lokale en systemische inflammatie
  278. Van Huffel Sofie  (21-sep-01; F. Van Roy & R.Beyaert)
    Identificatie en functionele karakterisering van eiwitten die binden met het zinkvingereiwit A20
  279. Vanhauwe Jurgen  (15-jun-01; G. Haegeman & J. Leysen)
    Karakterisering van de ligand-bindings- en signaaltransductie-eigenschappen van humane dopamine D2- en D3-receptoren
  280. Francken Bart  (17-apr-01; G. Haegeman)
    Heterologous expression of G protein-coupled receptors and reconstituion of G protein coupling : h5-ht5A receptor in mammalian, insect, and bacterial cells
  281. De Wilde Gert  (10-jan-01; G. Haegeman)
    Studie van de ruimtelijke structuur van het TNFR-55 'death domain' en van de stroomafwaartse signalisatie naar MAP-kinasen
  282. Schotte Peter  (15-dec-00; R. Beyaert &F. Van Roy)
    Studie van caspasen en het activeringsmechanismen
  283. Van Craenenbroeck Kathleen  (21-jun-00; G. Haegeman)
    Onderzoek van induceerbare systemen voor heterologene genexpressie in zoogdiercellen
  284. Vanlandschoot Ann  (10-mei-00; F. Van Roy)
    Isolering en karakterisering van catenine- en cadherine-bindende eiwitten met mogelijke functies in signalisatiewegen en genregulatie
  285. Laroy Wouter  (9-mei-00; R. Contreras)
    Structuur-functie analyse van siaalzuur transfererende enzymen
  286. De Bosscher Karolien  (23-mrt-00; G. Haegeman)
    Onderzoek naar het mechanisme van Genrepressie door Glucocorticoïden
  287. Denecker Geertrui  (17-mrt-00; W. Fiers & P. Vandenabeele)
    Role of capases and mitochondria in apoptotic and necrontic cell death
  288. De Backer Marianne  (11-feb-00; R. Contreras)
    Identification of novel molecular targets for drugs against Candida albicans
  289. Dooms Hans  (28-jan-00; J. Grooten &F. Van Roy)
    Differentiële regulatie van apoptose en celdeling door interleukine-2 en -15 tijdens T-lymfocyt-antwoorden