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Afonina, IS, Van Nuffel, E, Beyaert, R.
Immune responses and therapeutic options in psoriasis
Cell Mol Life Sci , in press, 2021. (Epub 2021 Jan 2)

Aguilera-Lizarraga, J, Florens, MV, Viola, MF, Jain, P, Decraecker, L, Appeltans, I, Cuende-Estevez, M, Fabre, N, Van Beek, K, Perna, E, Balemans, D, Stakenborg, N, Theofanous, S, Bosmans, G, Mondelaers, SU, Matteoli, G, Ibiza Martinez, S, Lopez-Lopez, C, Jaramillo-Polanco, J, et al..
Local immune response to food antigens drives meal-induced abdominal pain
Nature 590, 151-156, 2021. (Epub 2021 Jan 13)

Almeida, L, Dhillon-LaBrooy, A, Castro, CN, Adossa, N, Carriche, GM, Guderian, M, Lippens, S, Dennerlein, S, Hesse, C, Lambrecht, BN, Berod, L, Schauser, L, Blazar, BR, Kalesse, M, Muller, R, Moita, LF, Sparwasser, T.
Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis
Immunity 54, 68-83, 2021. (Epub 2020 Nov 24)

Backers, L, Parton, B, De Bruyne, M, Tavernier, SJ, Van Den Bogaert, K, Lambrecht, BN, Haerynck, F, Claes, KBM.
Missing heritability in Bloom syndrome: First report of a deep intronic variant leading to pseudo-exon activation in the BLM gene
Clin Genet 99, 292-297, 2021. (Epub 2020 Oct 9)

Bosteels, C, Fierens, K, De Prijck, S, Van Moorleghem, J, Vanheerswynghels, M, De Wolf, C, Chalon, A, Collignon, C, Hammad, H, Didierlaurent, AM, Lambrecht, BN.
CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Immunity by the Human Vaccine Adjuvant System AS01
Front Immunol 11, 606805, 2021. (Epub 2021 Jan 14)

Carbo, JM, Leon, TE, Font-Diaz, J, De la Rosa, JV, Castrillo, A, Picard, FR, Staudenraus, D, Huber, M, Cedo, L, Escola-Gil, JC, Campos, L, Bakiri, L, Wagner, EF, Caelles, C, Stratmann, T, Van Ginderachter, JA, Valledor, AF.
Pharmacological activation of LXR alters the expression profile of tumor-associated macrophages and the abundance of regulatory T cells in the tumor microenvironment
Cancer Res 81, 968-985, 2021. (Epub 2020 Dec 23)

Delaney, C, Farrell, M, Doherty, CP, Brennan, K, O'Keeffe, E, Greene, C, Byrne, K, Kelly, E, Birmingham, N, Hickey, P, Cronin, S, Savvides, SN, Doyle, SL, Campbell, M.
Attenuated CSF-1R signalling drives cerebrovascular pathology
EMBO Mol Med 13, e12889, 2021. (Epub 2020 Dec 22)

Desmet, S, Saeys, Y, Verstaen, K, Dauwe, R, Kim, H, Niculaes, C, Fukushima, A, Goeminne, G, Vanholme, R, Ralph, J, Boerjan, W, Morreel, K.
Maize specialized metabolome networks reveal organ-preferential mixed glycosides
Comput Struct Biotechnol J 19, 1127-1144, 2021. (Epub 2021 jan 26)

Dhont, S, Derom, E, Van Braeckel, E, Depuydt, P, Lambrecht, BN.
Conceptions of the pathophysiology of happy hypoxemia in COVID-19
Respir Res 22, 12, 2021. (Epub 2021 Jan 8)

Fleischmann, RM, Blanco, R, Hall, S, Thomson, GTD, Van den Bosch, FE, Zerbini, C, Bessette, L, Enejosa, J, Li, Y, Song, Y, DeMasi, R, Song, IH.
Switching between Janus kinase inhibitor upadacitinib and adalimumab following insufficient response: efficacy and safety in patients with rheumatoid arthritis
Ann Rheum Dis 80, 432-439, 2021. (Epub 2020 Nov 4)

Germanova, D, Keirsse, J, Kohler, A, Hastir, JF, Demetter, P, Delbauve, S, Elkrim, Y, Verset, L, Larbanoix, L, Preyat, N, Laurent, S, Nedospasov, S, Donckier, V, Van Ginderachter, JA, Flamand, V.
Myeloid TNF and HO-1 regulate the progression of colorectal liver metastases during hepatic ischemia-reperfusion
Int J Cancer 148, 12761288, 2021. (Epub 2020 Oct 10)

Gorle, N, Bauwens, E, Haesebrouck, F, Smet, A, Vandenbroucke, RE.
Helicobacter and the Potential Role in Neurological Disorders: There Is More Than Helicobacter pylori
Front Immunol 11, 584165, 2021. (Epub 2021 Jan 28)

Guggino, G, Mauro, D, Rizzo, A, Alessandro, R, Raimondo, S, Bergot, AS, Rahman, MA, Ellis, JJ, Milling, S, Lories, R, Elewaut, D, Brown, MA, Thomas, R, Ciccia, F.
Inflammasome activation in Ankylosing Spondylitis is associated to gut dysbiosis
Arthritis Rheumatol , in press, 2021. (Epub 2021 Jan 16)

Guilliams, M, Svedberg, FR.
Does tissue imprinting restrict macrophage plasticity?
Nat Immunol 22, 118-127, 2021. (Epub 2021 Jan 18)

Jangra, S, De Vrieze, J, Choi, A, Rathnasinghe, R, Laghlali, G, Uvyn, A, Van Herck, S, Nuhn, L, Deswarte, K, Zhong, Z, Sanders, N, Lienenklaus, S, David, S, Strohmeier, S, Amanat, F, Krammer, F, Hammad, H, Lambrecht, BN, Coughlan, L, et al..
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine
Angew Chem Int Ed Engl , in press, 2021. (Epub 2021 Jan 19)

Jans, LBO, Chen, M, Elewaut, D, Van den Bosch, F, Carron, P, Jacques, P, Wittoek, R, Jaremko, JL, Herregods, N.
MRI-based Synthetic CT in the Detection of Structural Lesions in Patients with Suspected Sacroiliitis: Comparison with MRI
Radiology 298, 343-349, 2021. (Epub 2020 Dec 22)

Jonckheere, S, Adams, J, De Groote, D, Campbell, K, Berx, G, Goossens, S.
Epithelial-Mesenchymal Transition (EMT) as a Therapeutic Target
Cells Tissues Organs , 1-26, 2021. (Epub 2021 Jan 5)

Kananen, L, Enroth, L, Raitanen, J, Jylhava, J, Burkle, A, Moreno-Villanueva, M, Bernhardt, J, Toussaint, O, Grubeck-Loebenstein, B, Malavolta, M, Basso, A, Piacenza, F, Collino, S, Gonos, ES, Sikora, E, Gradinaru, D, Jansen, E, Dolle, MET, Salmon, M, et al..
Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains
Sci Rep 11, 6139, 2021. (Epub 2021 Mar 17)

Kim, JS, Kolesnikov, M, Peled-Hajaj, S, Scheyltjens, I, Xia, Y, Trzebanski, S, Haimon, Z, Shemer, A, Lubart, A, Van Hove, H, Chappell-Maor, L, Boura-Halfon, S, Movahedi, K, Blinder, P, Jung, S.
A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages
Immunity 54, 176-190, 2021. (Epub 2020 Dec 16)

Kiss, M, Vande Walle, L, Saavedra, PHV, Lebegge, E, Van Damme, H, Murgaski, A, Qian, J, Ehling, M, Pretto, S, Bolli, E, Keirsse, J, Bardet, PMR, Arnouk, SM, Elkrim, Y, Schmoetten, M, Brughmans, J, Debraekeleer, A, Fossoul, A, Boon, L, et al..
IL1beta Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D
Cancer Immunol Res 9, 309-323, 2021. (Epub 2020 Dec 23)

Klionsky, DJ, Abdel-Aziz, AK, Abdelfatah, S, Abdellatif, M, Abdoli, A, Abel, S, Abeliovich, H, Abildgaard, MH, Abudu, YP, Acevedo-Arozena, A, Adamopoulos, IE, Adeli, K, Adolph, TE, Adornetto, A, Aflaki, E, Agam, G, Agarwal, A, Aggarwal, BB, Agnello, M, et al..
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Autophagy , 1-382, 2021. (Epub 2021 Feb 8)

Lahmar, Q, Schouppe, E, Morias, Y, Van Overmeire, E, De Baetselier, P, Movahedi, K, Laoui, D, Sarukhan, A, Van Ginderachter, JA.
Monocytic myeloid-derived suppressor cells home to tumor-draining lymph nodes via CCR2 and locally modulate the immune response
Cell Immunol 362, 104296, 2021. (Epub 2021 Jan 30)

Le Naour, J, Liu, P, Zhao, L, Adjemian, S, Sztupinszki, Z, Taieb, J, Mulot, C, Silvin, A, Dutertre, CA, Ginhoux, F, et al., Vandenabeele, P, et al., Kroemer, G.
A TLR3 ligand reestablishes chemotherapeutic responses in the context of FPR1 deficiency
Cancer Discov 11, 408-423, 2021. (Epub 2020 Oct 12)

Lichawska-Cieslar, A, Konieczny, P, Szukala, W, Declercq, W, Fu, M, Jura, J.
Loss of keratinocyte Mcpip1 abruptly activates the IL-23/Th17 and Stat3 pathways in skin inflammation
Biochim Biophys Acta Mol Cell Res 1868, 118866, 2021. (Epub 2020 Sep 29)

Maschalidi, S, Ravichandran, KS.
Phagocytosis: Sweet Repulsions via the Glycocalyx
Curr Biol 31, R20-R22, 2021. (Epub 2021 Jan 11)

Mease, PJ, Lertratanakul, A, Anderson, JK, Papp, K, Van den Bosch, F, Tsuji, S, Dokoupilova, E, Keiserman, M, Wang, X, Zhong, S, McCaskill, RM, Zueger, P, Pangan, AL, Tillett, W.
Upadacitinib for psoriatic arthritis refractory to biologics: SELECT-PsA 2
Ann Rheum Dis 80, 312-320, 2021. (Epub 2020 Dec 3)

Meyts, I, Bucciol, G, Quinti, I, Neven, B, Fischer, A, Seoane, E, Lopez-Granados, E, Gianelli, C, Robles-Marhuenda, A, Jeandel, PY, Paillard, C, Sankaran, VG, Demirdag, YY, et al, Bosteels, C, Lambrecht, BN, et al..
Coronavirus Disease 2019 in patients with inborn errors of immunity: an international study
J Allergy Clin Immunol 147, 520-531, 2021. (Epub 2020 Sep 24)

Naesens, L, Smet, J, Tavernier, SJ, Schelstraete, P, Hoste, L, Lambrecht, S, Verhelst, H, van der Werff Ten Bosch, J, Ferster, A, Blumental, S, Hilbert, P, Kerre, T, Vande Walle, J, Licht, C, Roumenina, LT, Stordeur, P, Haerynck, F.
Plasma C3d levels as a diagnostic marker for complete complement factor I deficiency
J Allergy Clin Immunol 147, 749-753, 2021. (Epub 2020 Aug 24)

Nash, P, Kerschbaumer, A, Dorner, T, Dougados, M, Fleischmann, RM, Geissler, K, McInnes, I, Pope, JE, van der Heijde, D, Stoffer-Marx, M, Takeuchi, T, Trauner, M, Winthrop, KL, de Wit, M, Aletaha, D, Baraliakos, X, Boehncke, WH, Emery, P, Isaacs, JD, et al..
Points to consider for the treatment of immune-mediated inflammatory diseases with Janus kinase inhibitors: a consensus statement
Ann Rheum Dis 80, 71-87, 2021. (Epub 2020 Nov 6)

Percier, P, De Prins, S, Tima, G, Beyaert, R, Grooten, J, Romano, M, Denis, O.
Aspergillus fumigatus Recognition by Dendritic Cells Negatively Regulates Allergic Lung Inflammation Through a TLR2/MyD88 Pathway
Am J Respir Cell Mol Biol 64, 39-49, 2021. (Epub 2020 Sep 24)

Poncet, AF, Bosteels, V, Hoffmann, E, Chehade, S, Rennen, S, Huot, L, Peucelle, V, Marechal, S, Khalife, J, Blanchard, N, Janssens, S, Marion, S.
The UPR sensor IRE1alpha promotes dendritic cell responses to control Toxoplasma gondii infection
EMBO Rep , e49617, 2021. (Epub 2021 Feb 15)

Rathinam, E, Govindarajan, S, Rajasekharan, S, Declercq, H, Elewaut, D, De Coster, P, Martens, L, Leybaert, L.
The calcium dynamics of human dental pulp stem cells stimulated with tricalcium silicate-based cements determine their differentiation and mineralization outcome
Sci Rep 11, 645, 2021. (Epub 2021 Jan 12)

Renson, T, Carron, P, De Craemer, AS, Deroo, L, de Hooge, M, Krabbe, S, Jans, L, Chen, M, Ostergaard, M, Van den Bosch, FE, Elewaut, D.
Axial involvement in patients with early peripheral spondyloarthritis: a prospective MRI study of sacroiliac joints and spine
Ann Rheum Dis 80, 103-108, 2021. (Epub 2020 Oct 28)

Ruh, M, Stemmler, MP, Frisch, I, Fuchs, K, van Roey, R, Kleemann, J, Roas, M, Schuhwerk, H, Eccles, RL, Agaimy, A, Baumhoer, D, Berx, G, Muller, F, Brabletz, T, Brabletz, S.
The EMT transcription factor ZEB1 blocks osteoblastic differentiation in bone development and osteosarcoma
J Pathol , in press, 2021. (Epub 2021 Mar 5)

Schett, G, Baraliakos, X, Van den Bosch, F, Deodhar, A, Ostergaard, M, Das Gupta, A, Mpofu, S, Fox, T, Winseck, A, Porter, B, Shete, A, Gensler, LS.
Secukinumab Efficacy on Enthesitis in Patients with Ankylosing Spondylitis: Pooled Analysis of Four Pivotal Phase 3 Studies
J Rheumatol in press, , 2021. (Epub 2021 Mar 15)

Shaabani, E, Sharifiaghdam, M, De Keersmaecker, H, De Rycke, R, De Smedt, S, Faridi-Majidi, R, Braeckmans, K, Fraire, JC.
Layer by Layer Assembled Chitosan-Coated Gold Nanoparticles for Enhanced siRNA Delivery and Silencing
Int J Mol Sci 22, 831, 2021. (Epub 2021 Jan 15)

Skordos, I, Demeyer, A, Beyaert, R.
Analysis of T cells in mouse lymphoid tissue and blood with flow cytometry
STAR Protoc 2, 100351, 2021. (Epub 2021 Feb 20)

Sun, X, He, X, Zhang, Y, Hosaka, K, Andersson, P, Wu, J, Wu, J, Jing, X, Du, Q, Hui, X, Ding, B, Guo, Z, Hong, A, Liu, X, Wang, Y, Ji, Q, Beyaert, R, Yang, Y, Li, Q, et al..
Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism
Gut , in press, 2021. (Epub 2021 Feb 10)

Timmermans, S, Libert, C.
Ratpost: a searchable database of protein-inactivating sequence variations in 40 sequenced rat-inbred strains
Mamm Genome 32, 1-11, 2021. (Epub 2021 Jan 22)

van Anken, E, Bakunts, A, Hu, CA, Janssens, S, Sitia, R.
Molecular Evaluation of Endoplasmic Reticulum Homeostasis Meets Humoral Immunity
Trends Cell Biol , in press, 2021. (Epub 2021 Mar 5)

Van Damme, H, Dombrecht, B, Kiss, M, Roose, H, Allen, E, Van Overmeire, E, Kancheva, D, Martens, L, Murgaski, A, Bardet, PMR, Blancke, G, Jans, M, Bolli, E, Martins, MS, Elkrim, Y, Dooley, J, Boon, L, Schwarze, JK, Tacke, F, Movahedi, K, Vandamme, N, Neyns, B, Ocak, S, Scheyltjens, I, Vereecke, L, Nana, FA, Merchiers, P, Laoui, D, Van Ginderachter, JA.
Therapeutic depletion of CCR8(+) tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy
J Immunother Cancer 9, e001749, 2021. (Epub 2021 Feb)

Vanden Bulcke, M, Vanhaecke, A, Deschepper, E, Cutolo, M, Jacques, P, Smith, V.
Laser speckle contrast analysis in rheumatoid arthritis: a pilot study
Clin Exp Rheumatol , in press, 2021. (Epub 2021 Mar 9)

Vanderhaeghen, T, Wallaeys, C, Libert, C.
Turning a pathogen protein into a therapeutic tool for sepsis
EMBO Mol Med 13, e13589, 2021. (Epub 2020 Dec 17)

Vanderkerken, M, Baptista, AP, De Giovanni, M, Fukuyama, S, Browaeys, R, Scott, CL, Norris, PS, Eberl, G, Di Santo, JP, Vivier, E, Saeys, Y, Hammad, H, Cyster, JG, Ware, CF, Tumanov, AV, De Trez, C, Lambrecht, BN.
ILC3s control splenic cDC homeostasis via lymphotoxin signaling
J Exp Med 218, e20190835, 2021. (Epub 2021 Mar 16)

Van Hove, L, Lecomte, K, Roels, J, Vandamme, N, Vikkula, HK, Hoorens, I, Ongenae, K, Hochepied, T, Donati, G, Saeys, Y, Quist, SR, Watt, FM, van Loo, G, Hoste, E.
Fibrotic enzymes modulate wound-induced skin tumorigenesis
EMBO Rep , e51573, 2021. (Epub 2021 Mar 29)

Van Lysebetten, D, Malfanti, A, Deswarte, K, Koynov, K, Golba, B, Ye, T, Zhong, Z, Kasmi, S, Lamoot, A, Chen, Y, Van Herck, S, Lambrecht, BN, Sanders, NN, Lienenklaus, S, David, SA, Vicent, MJ, De Koker, S, De Geest, BG.
Lipid-Polyglutamate Nanoparticle Vaccine Platform
ACS Appl Mater Interfaces 13, 6011-6022, 2021. (Epub 2021 Jan 28)

van Uden, D, Koudstaal, T, van Hulst, JAC, Bergen, IM, Gootjes, C, Morrell, NW, van Loo, G, von der Thusen, JH, van den Bosch, TPP, Ghigna, MR, Perros, F, Montani, D, Kool, M, Boomars, KA, Hendriks, RW.
Central Role of Dendritic Cells in Pulmonary Arterial Hypertension in Human and Mice
Int J Mol Sci 22, 1756, 2021. (Epub 2021 Feb 10)

Yperman, K, Wang, J, Eeckhout, D, Winkler, J, Vu, LD, Vandorpe, M, Grones, P, Mylle, E, Kraus, M, Merceron, R, Nolf, J, Mor, E, De Bruyn, P, Loris, R, Potocky, M, Savvides, SN, De Rybel, B, De Jaeger, G, Van Damme, D, et al..
Molecular architecture of the endocytic TPLATE complex
Sci Adv 7, eabe7999, 2021. (Epub 2021 Feb 26)

Aaes, TL, Vandenabeele, P.
The intrinsic immunogenic properties of cancer cell lines, immunogenic cell death, and how these influence host antitumor immune responses
Cell Death Differ 28, 843-860, 2020. (Epub 2020 Nov 19)

Aaes, TL, Verschuere, H, Kaczmarek, A, Heyndrickx, L, Wiernicki, B, Delrue, I, De Craene, B, Taminau, J, Delvaeye, T, Bertrand, MJM, Declercq, W, Berx, G, Krysko, DV, Adjemian, S, Vandenabeele, P.
Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
J Immunol 204, 775-787, 2020. (Epub 2020 Jan 3)

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