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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Aegerter, H, Lambrecht, BN. The Pathology of Asthma: What Is Obstructing Our View? Annu Rev Pathol 18, 387-409, 2023. (Epub 2022 Oct 21) 
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Landewe, RBM, Poddubnyy, D, Rahman, P, Van den Bosch, FE, Bolce, R, Liu Leage, S, Lisse, JR, Park, SY, Gensler, L. Recapture and retreatment rates with ixekizumab after withdrawal of therapy in patients with axial spondyloarthritis: results at week 104 from a randomised placebo-controlled withdrawal study Ann Rheum Dis 82, 212-216, 2023. (Epub 2022 Sep 13)
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Mees, MA, Boone, F, Bouwen, T, Vanaerschot, F, Titeca, C, Vikkula, HK, Catrysse, L, Vananroye, A, Koos, E, Alexandris, S, Rosenfeldt, S, Eyley, S, Koetz, J, van Loo, G, Thielemans, W, Hoste, E.. Glycyrrhizin-Based Hydrogels Accelerate Wound Healing of Normoglycemic and Diabetic Mouse Skin Pharmaceutics 15, 27, 2023. (Epub 2022 Dec 21)
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Mortier, C, Gracey, E, Coudenys, J, Manuello, T, Decruy, T, Maelegheer, M, Stappers, F, Gilis, E, Gaublomme, D, Van Hoorebeke, L, Van Welden, S, Ambler, C, Hegen, M, Symanowicz, P, Steyn, S, Berstein, G, Elewaut, D, Venken, K. RORgammat inhibition ameliorates IL-23 driven experimental Psoriatic Arthritis by predominantly modulating gammadelta-T cells Rheumatology (Oxford) , in press, 2023. (Epub 2023 Jan 20)
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Aegerter, H, Lambrecht, BN, Jakubzick, CV. Biology of lung macrophages in health and disease Immunity 55, 1564-1580, 2022. (Epub 2022 Sep 13)
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Afzali, B, Noris, M, Lambrecht, BN, Kemper, C. The state of complement in COVID-19 Nat Rev Immunol 22, 77-84, 2022. (Epub 2021 Dec 15)
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An, H, Qian, C, Huang, Y, Li, J, Tian, X, Feng, J, Hu, J, Fang, Y, Jiao, F, Zeng, Y, Huang, X, Meng, X, Liu, X, Lin, X, Zeng, Z, Guilliams, M, Beschin, A, Chen, Y, Wu, Y, et al.. Functional vulnerability of liver macrophages to capsules defines virulence of blood-borne bacteria J Exp Med 219, e20212032, 2022. (Epub 2022 Apr 4)
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Arnouk, S, De Groof, TWM, Van Ginderachter, JA. Imaging and therapeutic targeting of the tumor immune microenvironment with biologics Adv Drug Deliv Rev 184, 114239, 2022. (Epub 2022 Mar 26)
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Arroyo-Hornero, R, Aegerter, H, Hamad, I, Corte-Real, B, Staes, K, van der Woning, B, Verstraete, K, Savvides, SN, Lambrecht, BN, Kleinewietfeld, M. The Charcot-Leyden crystal protein Galectin-10 is not a major determinant of human regulatory T-cell function Allergy , in press, 2022. (Epub 2022 May 1)
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Baeten, P, Van Zeebroeck, L, Kleinewietfeld, M, Hellings, N, Broux, B. Improving the Efficacy of Regulatory T Cell Therapy Clin Rev Allergy Immunol 62, 363-381, 2022. (Epub 2021 Jul 5)
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Baraliakos, X, Ostergaard, M, Lambert, RG, Eshed, I, Machado, PM, Pedersen, SJ, Weber, U, de Hooge, M, Sieper, J, Poddubnyy, D, Rudwaleit, M, van der Heijde, D, Landewe, RB, Maksymowych, WP. MRI lesions of the spine in patients with axial spondyloarthritis: an update of lesion definitions and validation by the ASAS MRI working group Ann Rheum Dis 81, 1243-1251, 2022. (Epub 2022 May 24)
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Berrio, RT, Verstaen, K, Vandamme, N, Pevernagie, J, Achon, I, Van Duyse, J, Van Isterdael, G, Saeys, Y, De Veylder, L, Inze, D, Dubois, M. Single-Cell Transcriptomics Sheds Light on the Identity and Metabolism of Developing Leaf Cells Plant Physiol 188, 898-918, 2022. (Epub 2021 Oct 23)
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Beterams, A, Calatayud Arroyo, M, De Paepe, K, De Craemer, AS, Elewaut, D, Venken, K, Van de Wiele, T. In vitro triple coculture with gut microbiota from spondyloarthritis patients is characterized by inter-individual differences in inflammatory responses Sci Rep 12, 10475, 2022. (Epub 2022 Jun 21)
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Bogaert, B, Sauvage, F, Guagliardo, R, Muntean, C, Nguyen, VP, Pottie, E, Wels, M, Minnaert, AK, De Rycke, R, Yang, Q, Peer, D, Sanders, N, Remaut, K, Paulus, YM, Stove, C, De Smedt, SC, Raemdonck, K. A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs J Control Release 350, 256-270, 2022. (Epub 2022 Aug 10)
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Bues, J, Biocanin, M, Pezoldt, J, Dainese, R, Chrisnandy, A, Rezakhani, S, Saelens, W, Gardeux, V, Gupta, R, Sarkis, R, Russeil, J, Saeys, Y, Amstad, E, Claassen, M, Lutolf, MP, Deplancke, B. Deterministic scRNA-seq captures variation in intestinal crypt and organoid composition Nat Methods 19, 323–330, 2022. (Epub 2022 Feb 14)
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Cao, L, Coventry, B, Goreshnik, I, Huang, B, Sheffler, W, Park, JS, Jude, KM, Markovic, I, Kadam, RU, Verschueren, KHG, Verstraete, K, Walsh, STR, Bennett, N, Phal, A, Yang, A, Kozodoy, L, DeWitt, M, Picton, L, Miller, L, et al.. Design of protein-binding proteins from the target structure alone Nature 605, 551-560, 2022. (Epub 2022 Mar 24)
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Caro, AA, Deschoemaeker, S, Allonsius, L, Coosemans, A, Laoui, D. Dendritic Cell Vaccines: A Promising Approach in the Fight against Ovarian Cancer Cancers (Basel) 14, 4037, 2022. (Epub 2022 Aug 21)
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Chauhan, D, Demon, D, Vande Walle, L, Paerewijck, O, Zecchin, A, Bosseler, L, Santoni, K, Planes, R, Ribo, S, Fossoul, A, Goncalves, A, Van Gorp, H, Van Opdenbosch, N, Van Hauwermeiren, F, Meunier, E, Wullaert, A, Lamkanfi, M. GSDMD drives canonical inflammasome-induced neutrophil pyroptosis and is dispensable for NETosis EMBO Rep , e54277, 2022. (Epub 2022 Jul 28)
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Ciurea, A, Kissling, S, Burki, K, Baraliakos, X, de Hooge, M, Hebeisen, M, Papagiannoulis, E, Exer, P, Bram, R, Nissen, MJ, Moller, B, Kyburz, D, Andor, M, Distler, O, Scherer, A, Micheroli, R. Current differentiation between radiographic and non-radiographic axial spondyloarthritis is of limited benefit for prediction of important clinical outcomes: data from a large, prospective, observational cohort RMD Open 8, e002067, 2022. (Epub 2022 Feb 2)
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Corte-Real, BFÂ, Arroyo Hornero, RÂ, Dyczko, AÂ, Hamad, IÂ, Kleinewietfeld, M. Dissecting the role of CSF2RB expression in human regulatory T cells Front Immunol 13, 1005965, 2022. (Epub 2022 Dec 2)
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Costantino, F, Aegerter, P, Schett, G, De Craemer, AS, Molto, A, Van den Bosch, F, Elewaut, D, Breban, M, D'Agostino, MA. Cluster analysis in early axial spondyloarthritis predicts poor outcome in the presence of peripheral articular manifestations Rheumatology (Oxford) 61, 3289–3298, 2022. (Epub 2021 Dec 3)
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Couckuyt, A, Seurinck, R, Emmaneel, A, Quintelier, K, Novak, D, Van Gassen, S, Saeys, Y. Challenges in translational machine learning Human Genetics 141, 1451–1466, 2022. (Epub 2022 Mar 4)
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D'Agostino, MA, Schett, G, Lopez-Rdz, A, Senolt, L, Fazekas, K, Burgos-Vargas, R, Maldonado-Cocco, J, Naredo, E, Carron, P, Duggan, AM, Goyanka, P, Boers, M, Gaillez, C. Response to Secukinumab on Synovitis using Power Doppler Ultrasound in Psoriatic Arthritis: 12-week Results from a Phase III Study, ULTIMATE Rheumatology (Oxford) 61, 1867-1876, 2022. (Epub 2021 Sep 16)
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De Bock, M, De Smet, MA, Verwaerde, S, Tahiri, H, Schumacher, S, Van Haver, V, Witschas, K, Steinhauser, C, Rouach, N, Vandenbroucke, RE, Leybaert, L. Targeting gliovascular connexins prevents inflammatory blood-brain barrier leakage and astrogliosis JCI Insight 7, e135263, 2022. (Epub 2022 Jul 26)
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Declercq, J, De Leeuw, E, Lambrecht, BN. Inflammasomes and IL-1 family cytokines in SARS-CoV-2 infection: from prognostic marker to therapeutic agent Cytokine 157, 155934, 2022. (Epub 2022 Jun 7)
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Declercq, J, Tobback, E, Vanhee, S, De Ruyck, N, Gerlo, S, Gevaert, P, Vandekerckhove, L. COVID-19 vaccination with BNT162b2 and ChAdOx1 vaccines has the potential to induce nasal neutralizing antibodies Allergy 77, 304-307, 2022. (Epub 2021 Sep 29)
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De Craemer, AS, Deroo, L, Renson, T, Desimpele, I, Delmez, L, Decuman, S, Janssens, X, Boonen, A, Elewaut, D, Carron, P, Van den Bosch, F. Work participation is unaffected in Belgian spondyloarthritis patients: data from the BelGian Inflammatory Arthritis and SpoNdylitis cohorT Rheumatology (Oxford) , in press, 2022. (Epub 2022 Sep 13)
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De Craemer, AS, Renson, T, Deroo, L, Van Praet, L, Cypers, H, Varkas, G, Joos, R, Devinck, M, Gyselbrecht, L, Peene, I, Thevissen, K, Costantino, F, D'Agostino, MA, Lenaerts, J, Carron, P, Van den Bosch, F, Elewaut, D. Peripheral manifestations are major determinants of disease phenotype and outcome in new onset spondyloarthritis Rheumatology (Oxford) 61, 3279–3288, 2022. (Epub 2021 Nov 30)
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De Craemer, AS, Witte, T, Lobaton Ortega, T, Hoorens, A, De Vos, M, Cuvelier, C, Vastert, SJ, Baraliakos, X, Van den Bosch, F, Elewaut, D. Anti-CD74 IgA antibodies show diagnostic potential for axial spondyloarthritis but are not associated with microscopic gut inflammation Rheumatology (Oxford) , in press, 2022. (Epub 2022 Jul 4)
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De Galan, C, Gonzales, GB, Van Welden, S, Tavernier, SJ, Lobaton, T, Van Moerkercke, W, Strubbe, B, Peeters, H, Macken, E, De Vos, M, Laukens, D, Hindryckx, P. Role of integrin expression in the prediction of response to vedolizumab: A prospective real-life multicentre cohort study Clin Transl Med 12, e769, 2022. (Epub 2022 Apr 5)
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De Galan, C, Truyens, M, Peeters, H, Mesonero Gismero, F, Elorza, A, Torres, P, Vandermeulen, L, Jauregui Amezaga, A, Ferreiro-Iglesias, R, Holvoet, T, Zabana, Y, Peries Reverter, L, Gonzales, GB, Geldof, J, Varkas, G, De Vos, M, Lobaton, T. The impact of vedolizumab and ustekinumab on articular extra-intestinal manifestations in inflammatory bowel disease patients: a real-life multicentric cohort study J Crohns Colitis , in press, 2022. (Epub 2022 Apr 20)
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de Haan, W, Dheedene, W, Apelt, K, Decombas-Deschamps, S, Vinckier, S, Verhulst, S, Conidi, A, Deffieux, T, Staring, MW, Vandervoort, P, Caluwe, E, Lox, M, Mannaerts, I, Takagi, T, Jaekers, J, Berx, G, Haigh, J, Topal, B, Zwijsen, A, et al.. Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis Cardiovasc Res 118, 1262-1275, 2022. (Epub 2021 Apr 28)
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De Leeuw, E, Bosteels, C, Lambrecht, BN, Hammad, H. Isolation of Conventional Murine Lung Dendritic Cell Subsets Methods Mol Biol 2506, 237-255, 2022. (Epub 2022 Jul 1)
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De Leeuw, E, Van Damme, KFA, Declercq, J, Bosteels, C, Maes, B, Tavernier, SJ, Detalle, L, Smart, T, Glatt, S, Debeuf, N, Deckers, J, Lameire, S, Vandecasteele, SJ, De Neve, N, Demedts, IK, Govaerts, E, Knoop, C, Vanhove, K, Moutschen, M, et al.. Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19: an open-label randomized controlled trial Respir Res 23, 202, 2022. (Epub 2022 Aug 9)
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Deneweth, J, Van de Peer, Y, Vermeirssen, V. Nearby transposable elements impact plant stress gene regulatory networks: a meta-analysis in A. thaliana and S. lycopersicum BMC Genomics 23, 18, 2022. (Epub 2022 Jan 4)
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Deodhar, A, Van den Bosch, F, Poddubnyy, D, Maksymowych, WP, van der Heijde, D, Kim, TH, Kishimoto, M, Blanco, R, Duan, Y, Li, Y, Pangan, AL, Wung, P, Song, IH. Upadacitinib for the treatment of active non-radiographic axial spondyloarthritis (SELECT-AXIS 2): a randomised, double-blind, placebo-controlled, phase 3 trial Lancet 400, 369-379, 2022. (Epub 2022 Jul 30)
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Deodhar, A, van der Heijde, D, Sieper, J, Van den Bosch, F, Maksymowych, WP, Kim, TH, Kishimoto, M, Ostor, A, Combe, B, Sui, Y, Chu, AD, Song, IH. Safety and Efficacy of Upadacitinib in Patients With Active Ankylosing Spondylitis and an Inadequate Response to Nonsteroidal Antiinflammatory Drug Therapy: One-Year Results of a Double-Blind, Placebo-Controlled Study and Open-Label Extension Arthritis Rheumatol 74, 70-80, 2022. (Epub 2021 Jul 1)
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De Ponti, FF, Scott, CL. A breath of fresh macrophages ameliorates inflammation in the hypoxic lung Nat Immunol 23, 820-822, 2022. (Epub 2022 May 26)
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De Ponti, FF, Scott, CL. Modulating hepatic macrophages with annexin A1 in non-alcoholic steatohepatitis Clin Sci (Lond) 136, 1111-1115, 2022. (Epub 2022 Aug 12)
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Deprez, J, Roovers, S, Lajoinie, G, Dewitte, H, Decruy, T, Coudenys, J, Descamps, B, Vanhove, C, Versluis, M, Elewaut, D, Jacques, P, De Smedt, SC, Lentacker, I. Evaluation of Liposome-Loaded Microbubbles as a Theranostic Tool in a Murine Collagen-Induced Arthritis Model Scientia Pharmaceutica 90, 17, 2022. (Epub 2022 Feb 28)
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de Reuver, R, Verdonck, S, Dierick, E, Nemegeer, J, Hessmann, E, Ahmad, S, Jans, M, Blancke, G, Van Nieuwerburgh, F, Botzki, A, Vereecke, L, van Loo, G, Declercq, W, Hur, S, Vandenabeele, P, Maelfait, J. ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation Nature 607, 784-789, 2022. (Epub 2022 Jul 20)
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Deroo, L, Achten, H, De Boeck, K, Genbrugge, E, Bauters, W, Roels, D, Dochy, F, Creytens, D, De Craemer, AS, Van den Bosch, F, Elewaut, D, Peene, I. Discriminative power of salivary gland ultrasound in relation to symptom-based endotypes in suspected and definite primary Sjogren's Syndrome Semin Arthritis Rheum 56, 152075, 2022. (Epub 2022 Jul 22)
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De Schutter, E, Ramon, J, Pfeuty, B, De Tender, C, Stremersch, S, Raemdonck, K, de Beeck, KO, Declercq, W, Riquet, FB, Braeckmans, K, Vandenabeele, P. Plasma membrane perforation by GSDME during apoptosis-driven secondary necrosis Cell Mol Life Sci 79, 19, 2022. (Epub 2021 Dec 31)
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De Spiegeleer, A, Van Migerode, J, Bronselaer, A, Wynendaele, E, Peelman, M, Vandaele, F, Byttebier, G, De Tre, G, Belmans, L, Van De Wiele, C, Sathekge, M, Van Dijck, D, Saxberg, B, Alexander, M, Fedson, D, Elewaut, D, Van Den Noortgate, N, De Spiegeleer, B. Statin Intake and All-Cause Mortality among Older Nursing Home Residents Gerontology 68, 407–411, 2022. (Epub 2021 Jun 16)
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De Spiegeleer, A, Wynendaele, E, Descamps, A, Debunne, N, Braeckman, BP, De Mey, M, Coudenys, J, Crombez, L, Verbeke, F, Janssens, Y, Janky, R, Goossens, E, Vlaeminck, C, Duchi, D, Andries, V, Dumas, E, Petrovic, M, Van de Wiele, T, Knappe, D, et al.. The bacterial quorum sensing peptide iAM373 is a novel inducer of sarcopenia Clin Transl Med 12, e1053, 2022. (Epub 2022 Oct 13)
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Detry, S, Andries, J, Bloch, Y, Gabay, C, Clancy, DM, Savvides, SN. Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein in inflammation and tumor immunity J Biol Chem 298, 101908, 2022. (Epub 2022 Apr 6)
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de Vlam, K, Toukap, AN, Kaiser, MJ, Vanhoof, J, Remans, P, Van den Berghe, M, Di Romana, S, Van den Bosch, F, Lories, R. Real-World Efficacy and Safety of Apremilast in Belgian Patients with Psoriatic Arthritis: Results from the Prospective Observational APOLO Study Adv Ther 39, 1055-1067, 2022. (Epub 2022 Jan 3)
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De Vlieger, L, Vandenbroucke, RE, Van Hoecke, L. Recent insights into viral infections as a trigger and accelerator in alzheimer's disease Drug Discov Today 27, 103340, 2022. (Epub 2022 Aug 18)
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De Vooght, L, De Ridder, K, Hussain, S, Stijlemans, B, De Baetselier, P, Caljon, G, Van Den Abbeele, J. Targeting the tsetse-trypanosome interplay using genetically engineered Sodalis glossinidius PLoS Pathog 18, e1010376, 2022. (Epub 2022 Mar 10)
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Dubouchet, L, Todorov, H, Seurinck, R, Vallet, N, Van Gassen, S, Corneau, A, Blanc, C, Zouali, H, Boland, A, Deleuze, JF, Ingram, B, de Latour, RP, Saeys, Y, Socie, G, Michonneau, D. Operational tolerance after hematopoietic stem cell transplantation is characterized by distinct transcriptional, phenotypic, and metabolic signatures Sci Transl Med 14, eabg3083, 2022. (Epub 2022 Feb 23)
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