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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Todorov, H, Cannoodt, R, Saelens, W, Saeys, Y. Network Inference from Single-Cell Transcriptomic Data Methods Mol Biol 1883, 235-249, 2019. (Epub 2018 Dec 14) 
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Todorov, H, Saeys, Y. Computational approaches for high-throughput single-cell data analysis FEBS J 286, 1451-1467, 2019. (Epub 2018 Jul 30)
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Umansky, V, Adema, GJ, Baran, J, Brandau, S, Van Ginderachter, JA, Hu, X, Jablonska, J, Mojsilovic, S, Papadaki, HA, Pico de Coana, Y, Santegoets, KCM, Santibanez, JF, Serre, K, Si, Y, Sieminska, I, Velegraki, M, Fridlender, ZG. Interactions among myeloid regulatory cells in cancer Cancer Immunol Immunother 68, 645-660, 2019. (Epub 2018 Jul 12)
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Underwood, J, De Francesco, D, Cole, JH, Caan, MWA, van Zoest, RA, Schmand, BA, Sharp, DJ, Sabin, CA, Reiss, P, Winston, A, COmorBidity in Relation to AIDS Collaboration and the, PacOiPof, Y. Study Group. Validation of a Novel Multivariate Method of Defining HIV-Associated Cognitive Impairment Open Forum Infect Dis 6, ofz198, 2019. (Epub 2019 May 3)
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Uvyn, A, De Coen, R, De Wever, O, Deswarte, K, Lambrecht, BN, De Geest, BG. Cell surface clicking of antibody-recruiting polymers to metabolically azide-labeled cancer cells Chem Commun (Camb) 55, 10952-10955, 2019. (Epub 2109 Sep 10)
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Vandamme, N, Berx, G. From neural crest cells to melanocytes: cellular plasticity during development and beyond Cell Mol Life Sci 76, 1919-1934, 2019. (Epub 2019 Mar 4)
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Vanden Berghe, T, Hoste, E. Paving the way for precision medicine v2.0 in intensive care by profiling necroinflammation in biofluids Cell Death Differ 26, 83–98, 2019. (Epub 2018 Sep 10)
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Van den Bosch, F, Flipo, RM, Braun, J, Vastesaeger, N, Kachroo, S, Govoni, M. Clinical and quality of life improvements with golimumab or infliximab in a real-life ankylosing spondylitis population: the QUO-VADIS study Clin Exp Rheumatol 37, 199-207, 2019. (Epub 2018 Jul 19)
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van der Heijde, D, Song, IH, Pangan, AL, Deodhar, A, van den Bosch, F, Maksymowych, WP, Kim, TH, Kishimoto, M, Everding, A, Sui, Y, Wang, X, Chu, AD, Sieper, J. Efficacy and safety of upadacitinib in patients with active ankylosing spondylitis (SELECT-AXIS 1): a multicentre, randomised, double-blind, placebo-controlled, phase 2/3 trial Lancet 394, 2108-2117, 2019. (Epub 2019 Nov 12)
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Vandewalle, J, Steeland, S, Van Ryckeghem, S, Eggermont, M, Van Wonterghem, E, Vandenbroucke, RE, Libert, C. A Study of Cecal Ligation and Puncture-Induced Sepsis in Tissue-Specific Tumor Necrosis Factor Receptor 1-Deficient Mice Front Immunol 10, 2574, 2019. (Epub 2019 Nov 8)
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Vande Walle, L, Stowe, IB, Sacha, P, Lee, BL, Demon, D, Fossoul, A, Van Hauwermeiren, F, Saavedra, PHV, Simon, P, Subr, V, Kostka, L, Stivala, CE, Pham, VC, Staben, ST, Yamazoe, S, Konvalinka, J, Kayagaki, N, Lamkanfi, M. MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition PLoS Biol 17, e3000354, 2019. (Epub 2019 Sep 16)
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Van Gorp, H, Lamkanfi, M. The emerging roles of inflammasome-dependent cytokines in cancer development EMBO Rep 20, e47575, 2019. (Epub 2019 May 17)
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Van Gorp, H, Van Opdenbosch, N, Lamkanfi, M. Inflammasome-Dependent Cytokines at the Crossroads of Health and Autoinflammatory Disease Cold Spring Harb Perspect Biol 11, a028563, 2019. (Epub 2017 Oct 16)
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Van Guyse, JFR, de la Rosa, VR, Lund, R, De Bruyne, M, De Rycke, R, Filippov, SK, Hoogenboom, R. Striking Effect of Polymer End-Group on C-60 Nanoparticle Formation by High Shear Vibrational Milling with Alkyne-Functionalized Poly(2-oxazoline)s Acs Macro Letters 8, 172-176, 2019. (Epub 2019 Jan 23)
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Van Hoecke, L, Raes, L, Stremersch, S, Brans, T, Fraire, JC, Roelandt, R, Declercq, W, Vandenabeele, P, Raemdonck, K, Braeckmans, K, Saelens, X. Delivery of Mixed-Lineage Kinase Domain-Like Protein by Vapor Nanobubble Photoporation Induces Necroptotic-Like Cell Death in Tumor Cells International Journal of Molecular Sciences 20, E4254, 2019. (Epub 2019 Aug 30)
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Vanholme, R, Sundin, L, Seetso, KC, Kim, H, Liu, X, Li, J, De Meester, B, Hoengenaert, L, Goeminne, G, Morreel, K, Haustraete, J, Tsai, HH, Schmidt, W, Vanholme, B, Ralph, J, Boerjan, W. COSY catalyses trans-cis isomerization and lactonization in the biosynthesis of coumarins Nat Plants 5, 1066-1075, 2019. (Epub 2019 Sep 9)
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Van Hove, H, Martens, L, Scheyltjens, I, De Vlaminck, K, Pombo Antunes, AR, De Prijck, S, Vandamme, N, De Schepper, S, Van Isterdael, G, Scott, CL, Aerts, J, Berx, G, Boeckxstaens, GE, Vandenbroucke, RE, Vereecke, L, Moechars, D, Guilliams, M, Van Ginderachter, JA, Saeys, Y, Movahedi, K. A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment Nat Neurosci 22, 1021–1035, 2019. (Epub 2019 May 6)
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Van Looveren, K, Van Boxelaere, M, Callaerts-Vegh, Z, Libert, C. Cognitive dysfunction in mice lacking proper glucocorticoid receptor dimerization PLoS One 14, e0226753, 2019. (Epub 2019 Dec 23)
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Van Malderen, SJM, Van Acker, T, Laforce, B, De Bruyne, M, de Rycke, R, Asaoka, T, Vincze, L, Vanhaecke, F. Three-dimensional reconstruction of the distribution of elemental tags in single cells using laser ablation ICP-mass spectrometry via registration approaches Anal Bioanal Chem 411, 4849-4859, 2019. (Epub 2019 Feb 21)
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Varasteh, Z, Mohanta, S, Li, Y, Lopez Armbruster, N, Braeuer, M, Nekolla, SG, Habenicht, A, Sager, HB, Raes, G, Weber, W, Hernot, S, Schwaiger, M. Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using (68)Ga-NOTA-anti-MMR nanobody: non-invasive imaging of atherosclerotic plaques EJNMMI Res 9, 5, 2019. (Epub 2019 Jan 21)
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Varkas, G, Ribbens, C, Louis, E, Van den Bosch, F, Lories, R, Vermeire, S, Elewaut, D, De Vos, M. Expert consensus: practical algorithms for management of inflammatory bowel disease patients presenting with back pain or peripheral arthropathies Aliment Pharmacol Ther 50, 1204-1213, 2019. (Epub 2019 Oct 25)
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Veale, DJ, McGonagle, D, McInnes, IB, Krueger, JG, Ritchlin, CT, Elewaut, D, Kanik, KS, Hendrikx, T, Berstein, G, Hodge, J, Telliez, JB. The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis Rheumatology (Oxford) 58, 197-205, 2019. (Epub 2018 Apr 3)
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Venken, K, Jacques, P, Mortier, C, Labadia, ME, Decruy, T, Coudenys, J, et al., Van Gassen, S, Martens, L, Smith, D, Harcken, C, Wahle, J, Wang, CT, Verheugen, E, Schryvers, N, Varkas, G, Cypers, H, et al.,Van den Bosch, F, Saeys, Y, Nabozny, G, Elewaut D. RORgammat inhibition selectively targets IL-17 producing iNKT and gammadelta-T cells enriched in Spondyloarthritis patients Nat Commun 10, 9, 2019. (Epub 2019 Jan 2)
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Verschueren, KHG, Blanchet, C, Felix, J, Dansercoer, A, De Vos, D, Bloch, Y, Van Beeumen, J, Svergun, D, Gutsche, I, Savvides, SN, Verstraete, K. Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle Nature 568, 571-575, 2019. (Epub 2019 Apr 3)
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Vetters, J, van Helden, MJ, Wahlen, S, Tavernier, SJ, Martens, A, Fayazpour, F, Vergote, K, Vanheerswynghels, M, Deswarte, K, Van Moorleghem, J, De Prijck, S, Takahashi, N, Vandenabeele, P, Boon, L, van Loo, G, Vivier, E, Lambrecht, BN, Janssens, S. The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF J Exp Med 216, 2010-2023, 2019. (Epub 2019 Jul 11)
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Vluymans, S, Mac Parthalain, N, Cornelis, C, Saeys, Y. Weight selection strategies for ordered weighted average based fuzzy rough sets Information Sciences 501, 155-171, 2019. (Epub 2019 May 29)
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Voet, S, Prinz, M, van Loo, G. Microglia in Central Nervous System Inflammation and Multiple Sclerosis Pathology Trends Mol Med 25, 112-123, 2019. (Epub 2018 Dec 18)
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Voet, S, Srinivasan, S, Lamkanfi, M, van Loo, G. Inflammasomes in neuroinflammatory and neurodegenerative diseases EMBO Mol Med 11, e10248, 2019. (Epub 2019 Apr 23)
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Vriens, K, Christen, S, Parik, S, Broekaert, D, Yoshinaga, K, Talebi, A, Dehairs, J, Escalona-Noguero, C, Schmieder, R, Cornfield, T, Charlton, C, Romero-Perez, L, Rossi, M, Rinaldi, G, Orth, MF, Boon, R, Kerstens, A, Kwan, SY, Faubert, B, et al.. Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity Nature 566, 403–406, 2019. (Epub 2019 Feb 6)
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Webb, LV, Barbarulo, A, Huysentruyt, J, Vanden Berghe, T, Takahashi, N, Ley, S, Vandenabeele, P, Seddon, B. Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-kappaB Immunity 50, 348-361, 2019. (Epub 2019 Jan 23)
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Weber, LM, Saelens, W, Cannoodt, R, Soneson, C, Hapfelmeier, A, Gardner, PP, Boulesteix, AL, Saeys, Y, Robinson, MD. Essential guidelines for computational method benchmarking Genome Biol 20, 125, 2019. (Epub 2019 Jun 20)
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Willebrand, R, Hamad, I, Van Zeebroeck, L, Kiss, M, Bruderek, K, Geuzens, A, Swinnen, D, Corte-Real, BF, Marko, L, Lebegge, E, Laoui, D, Kemna, J, Kammertoens, T, Brandau, S, Van Ginderachter, JA, Kleinewietfeld, M. High Salt Inhibits Tumor Growth by Enhancing Anti-tumor Immunity Front Immunol 10, 1141, 2019. (Epub 2019 Jun 4)
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Xavier, C, Blykers, A, Laoui, D, Bolli, E, Vaneyken, I, Bridoux, J, Baudhuin, H, Raes, G, Everaert, H, Movahedi, K, Van Ginderachter, JA, Devoogdt, N, Caveliers, V, Lahoutte, T, Keyaerts, M. Clinical Translation of [(68)Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages Mol Imaging Biol 21, 898-906, 2019. (Epub 2019 Jan 22)
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Zhang, Z, Li, H, Kasmi, S, Van Herck, S, Deswarte, K, Lambrecht, B, Hoogenboom, R, Nuhn, L, de Geest, B. A Synthetic Transiently Thermoresponsive Homopolymer with UCST Behaviour within a Physiologically Relevant Window Angew Chem Int Ed Engl 58, 7866-7872, 2019. (Epub 2019 Mar 29)
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Zheng, F, Luo, S, Ouyang, Z, Zhou, J, Mo, H, Schoonooghe, S, Muyldermans, S, De Baetselier, P, Raes, G, Wen, Y. NIRF-Molecular Imaging with Synovial Macrophages-Targeting Vsig4 Nanobody for Disease Monitoring in a Mouse Model of Arthritis Int J Mol Sci 20, 3347, 2019. (Epub 2019 Jul 8)
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Zhong, Z, Portela Catani, JP, Mc Cafferty, S, Couck, L, Van Den Broeck, W, Gorle, N, Vandenbroucke, RE, Devriendt, B, Ulbert, S, Cnops, L, Michels, J, Arien, KK, Sanders, NN. Immunogenicity and Protection Efficacy of a Naked Self-Replicating mRNA-Based Zika Virus Vaccine Vaccines (Basel) 7, 96, 2019. (Epub 2019 Aug 23)
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Adanitsch, F, Shi, J, Shao, F, Beyaert, R, Heine, H, Zamyatina, A. Synthetic glycan-based TLR4 agonists targeting caspase-4/11 for the development of adjuvants and immunotherapeutics Chem Sci 9, 3957-3963, 2018. (Epub 2018 Mar 15)
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Alissafi, T, Kourepini, E, Simoes, DCM, Paschalidis, N, Aggelakopoulou, M, Sparwasser, T, Boon, L, Hammad, H, Lambrecht, BN, Panoutsakopoulou, V. Osteopontin Promotes Protective Antigenic Tolerance against Experimental Allergic Airway Disease J Immunol 200, 1270-1282, 2018. (Epub 2018 Jan 12)
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Andersson, P, Yang, Y, Hosaka, K, Zhang, Y, Fischer, C, Braun, H, Liu, S, Yu, G, Liu, S, Beyaert, R, Chang, M, Li, Q, Cao, Y. Molecular mechanisms of IL-33-mediated stromal interactions in cancer metastasis JCI Insight 3, e122375, 2018. (Epub 2018 Oct 18)
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Annibaldi, A, Wicky John, S, Vanden Berghe, T, Swatek, KN, Ruan, J, Liccardi, G, Bianchi, K, Elliott, PR, Choi, SM, Van Coillie, S, Bertin, J, Wu, H, Komander, D, Vandenabeele, P, Silke, J, Meier, P. Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2 Mol Cell 69, 566-580, 2018. (Epub 2018 Feb 15)
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Antonioli, L, Blandizzi, C, Pacher, P, Guilliams, M, Hasko, G. Quorum sensing in the immune system Nat Rev Immunol 18, 537-538, 2018. (Epub 2018 Jul 13)
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Bala, G, Baudhuin, H, Remory, I, Gillis, K, Debie, P, Krasniqi, A, Lahoutte, T, Raes, G, Devoogdt, N, Cosyns, B, Hernot, S. Evaluation of [(99m)Tc]Radiolabeled Macrophage Mannose Receptor-Specific Nanobodies for Targeting of Atherosclerotic Lesions in Mice Mol Imaging Biol 20, 260-267, 2018. (Epub 2017 Sep 5)
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Ballegeer, M, Van Looveren, K, Timmermans, S, Eggermont, M, Vandevyver, S, Thery, F, Dendoncker, K, Souffriau, J, Vandewalle, J, Van Wyngene, L, De Rycke, R, Takahashi, N, Vandenabeele, P, Tuckermann, J, Reichardt, HM, Impens, F, Beyaert, R, De Bosscher, K, Vandenbroucke, RE, et al.. Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice J Clin Invest 128, 3265-3279, 2018. (Epub 2018 May 10)
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Berings, M, Gevaert, P, De Ruyck, N, Derycke, L, Holtappels, G, Pilette, C, Bachert, C, Lambrecht, BN, Dullaers, M. FcepsilonRI expression and IgE binding by dendritic cells and basophils in allergic rhinitis and upon allergen immunotherapy Clin Exp Allergy 48, 970-980, 2018. (Epub 2018 Apr 22)
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Beute, J, Lukkes, M, Koekoek, EP, Nastiti, H, Ganesh, K, de Bruijn, MJ, Hockman, S, van Nimwegen, M, Braunstahl, GJ, Boon, L, Lambrecht, BN, Manganiello, VC, Hendriks, RW, KleinJan, A. A pathophysiological role of PDE3 in allergic airway inflammation JCI Insight 3, e94888, 2018. (Epub 2018 Jan 25)
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Beyaert, R, Libert, C. How Good Roommates Can Protect against Microbial Sepsis Cell Host Microbe 23, 283-285, 2018. (Epub 2018 Mar 14)
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Bhosale, R, Boudolf, V, Cuevas, F, Lu, R, Eekhout, T, Hu, Z, Van Isterdael, G, Lambert, GM, Xu, F, Nowack, MK, Smith, RS, Vercauteren, I, De Rycke, R, Storme, V, Beeckman, T, Larkin, JC, Kremer, A, Hofte, H, Galbraith, DW, et al.. A Spatiotemporal DNA Endoploidy Map of the Arabidopsis Root Reveals Roles for the Endocycle in Root Development and Stress Adaptation Plant Cell 30, 2330-2351, 2018. (Epub 2018 Oct)
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Boeck, C, Pfister, S, Burkle, A, Vanhooren, V, Libert, C, Salinas-Manrique, J, Dietrich, DE, Kolassa, IT, Karabatsiakis, A. Alterations of the serum N-glycan profile in female patients with Major Depressive Disorder J Affect Disord 234, 139-147, 2018. (Epub 2018 Feb 27)
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Bogaert, DJ, Kuehn, HS, Bonroy, C, Calvo, KR, Dehoorne, J, Vanlander, AV, De Bruyne, M, Cytlak, U, Bigley, V, De Baets, F, De Baere, E, Rosenzweig, SD, Haerynck, F, Dullaers, M. A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects J Allergy Clin Immunol 141, 432-435, 2018. (Epub 2017 Sep 18)
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Bogie, JF, Boelen, E, Louagie, E, Delputte, P, Elewaut, D, van Horssen, J, Hendriks, JJ, Hellings, N. CD169 is a marker for highly pathogenic phagocytes in multiple sclerosis Multiple Sclerosis Journal 24, 290-300, 2018. (Epub 2017 Mar 1)
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