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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Van den Broek, B, Pintelon, I, Hamad, I, Kessels, S, Haidar, M, Hellings, N, Hendriks, JJA, Kleinewietfeld, M, Brone, B, Timmerman, V, Timmermans, JP, Somers, V, Michiels, L, Irobi, J. Microglial derived extracellular vesicles activate autophagy and mediate multi-target signaling to maintain cellular homeostasis Journal of Extracellular Vesicles 10, e12022, 2020. (Epub 2020 Nov 25) 
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Vandendriessche, C, Bruggeman, A, Van Cauwenberghe, C, Vandenbroucke, RE. Extracellular Vesicles in Alzheimer's and Parkinson's Disease: Small Entities with Large Consequences Cells 9, 2485, 2020. (Epub 2020 Nov 15)
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Vanderhaeghen, T, Vandewalle, J, Libert, C. Hypoxia-inducible factors in metabolic reprogramming during sepsis FEBS J 287, 1478-1495, 2020. (Epub 2020 Jan 23)
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Van der Jeught, K, Sun, Y, Fang, Y, Zhou, Z, Jiang, H, Yu, T, Yang, J, Kamocka, MM, So, KM, Li, Y, Eyvani, H, Sandusky, GE, Frieden, M, Braun, H, Beyaert, R, He, X, Zhang, X, Zhang, C, Paczesny, S, et al.. ST2 as checkpoint target for colorectal cancer immunotherapy JCI Insight 5, 136073, 2020. (Epub 2020 May 7)
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Vanderkerken, M, Maes, B, Vandersarren, L, Toussaint, W, Deswarte, K, Vanheerswynghels, M, Pouliot, P, Martens, L, Van Gassen, S, Arthur, CM, Kirkling, ME, Reizis, B, Conrad, D, Stowell, S, Hammad, H, Lambrecht, BN. TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells Proc Natl Acad Sci U S A 117, 31331-31342, 2020. (Epub 2020 Nov 19)
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Van de Sande, B, Flerin, C, Davie, K, De Waegeneer, M, Hulselmans, G, Aibar, S, Seurinck, R, Saelens, W, Cannoodt, R, Rouchon, Q, Verbeiren, T, De Maeyer, D, Reumers, J, Saeys, Y, Aerts, S. A scalable SCENIC workflow for single-cell gene regulatory network analysis Nat Protoc 15, 2247-2276, 2020. (Epub 2020 Jun 19)
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Vandewalle, J, Libert, C. GILZ in sepsis: "Poor is the pupil who does not surpass his master" Eur J Immunol 50, 490-493, 2020. (Epub 2020 Feb 27)
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Vandewalle, J, Libert, C. Glucocorticoids in Sepsis: To Be or Not to Be Front Immunol 11, 1318, 2020. (Epub 2020 Jul 21)
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Vandewalle, J, Vanderhaeghen, T, Beyaert, R, Libert, C. Taking the STING Out of Sepsis? Cell Host Microbe 27, 491-493, 2020. (Epub 2020 Apr 8)
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Van Dingenen, J, Pieters, L, Van Nuffel, E, Lefebvre, RA. Hemin reduces postoperative ileus in a heme oxygenase 1-dependent manner while dimethyl fumarate does without heme oxygenase 1-induction Neurogastroenterol Motil , e13624, 2020. (Epub 2019 May 23)
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Van Gassen, S, Gaudilliere, B, Angst, MS, Saeys, Y, Aghaeepour, N. CytoNorm: A Normalization Algorithm for Cytometry Data Cytometry A 97, 268-278, 2020. (Epub 2019 Oct 21)
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Van Gorp, H, Huang, L, Saavedra, P, Vuylsteke, M, Asaoka, T, Prencipe, G, Insalaco, A, Ogunjimi, B, Jeyaratnam, J, Cataldo, I, Jacques, P, Vermaelen, K, Dullaers, M, Joos, R, Sabato, V, Stella, A, Frenkel, J, De Benedetti, F, Dehoorne, J, et al.. Blood-based test for diagnosis and functional subtyping of familial Mediterranean fever Ann Rheum Dis 79, 960-968, 2020. (Epub 2020 Apr 20)
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Van Hove, H, Pombo Antunes, AR, De Vlaminck, K, Scheyltjens, I, Van Ginderachter, JA, Movahedi, K. Identifying the variables that drive tamoxifen-independent CreERT2 recombination: Implications for microglial fate mapping and gene deletions Eur J Immunol 50, 459-463, 2020. (Epub 2019 Nov 30)
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Van Looveren, K, Timmermans, S, Vanderhaeghen, T, Wallaeys, C, Ballegeer, M, Souffriau, J, Eggermont, M, Vandewalle, J, Van Wyngene, L, De Bosscher, K, Libert, C. Glucocorticoids limit lipopolysaccharide-induced lethal inflammation by a double control system EMBO Rep 21, e49762, 2020. (Epub 2020 May 8)
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Van Looveren, K, Van Wyngene, L, Libert, C. An extracellular microRNA can rescue lives in sepsis EMBO Rep , e49193, 2020. (Epub 2019 Nov 14)
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Van Looveren, K, Wallaeys, C, Libert, C. Potential of glucocorticoids to treat intestinal inflammation during sepsis Curr Opin Pharmacol 53, 1-7, 2020. (Epub 2020 Jan 25)
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Van Nuffel, E, Staal, J, Baudelet, G, Haegman, M, Driege, Y, Hochepied, T, Afonina, IS, Beyaert, R. MALT1 targeting suppresses CARD14-induced psoriatic dermatitis in mice EMBO Rep 21, e49237, 2020. (Epub 2020 Apr 28)
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van Olst, L, Verhaege, D, Franssen, M, Kamermans, A, Roucourt, B, Carmans, S, Ytebrouck, E, van der Pol, SMA, Wever, D, Popovic, M, Vandenbroucke, RE, Sobrino, T, Schouten, M, de Vries, HE. Microglial activation arises after aggregation of phosphorylated-tau in a neuron-specific P301S tauopathy mouse model Neurobiol Aging 89, 89-98, 2020. (Epub 2020 Jan 10)
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Vanslembrouck, B, Kremer, A, Van Roy, F, Lippens, S, van Hengel, J. Unravelling the ultrastructural details of alphaT-catenin-deficient cell-cell contacts between heart muscle cells by the use of FIB-SEM J Microsc 279, 189–196 , 2020. (Epub 2019 Dec 11)
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Van Wyngene, L, Vanderhaeghen, T, Timmermans, S, Vandewalle, J, Van Looveren, K, Souffriau, J, Wallaeys, C, Eggermont, M, Ernst, S, Van Hamme, E, Goncalves, A, Eelen, G, Remmerie, A, Scott, CL, Rombouts, C, Vanhaecke, L, De Bus, L, Decruyenaere, J, Carmeliet, P, et al.. Hepatic PPARalpha function and lipid metabolic pathways are dysregulated in polymicrobial sepsis EMBO Mol Med , e11319, 2020. (Epub 2020 Jan 9)
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Verboom, L, Martens, A, Priem, D, Hoste, E, Sze, M, Vikkula, HK, Van Hove, L, Voet, S, Roels, J, Maelfait, J, Bongiovanni, L, de Bruin, A, Scott, CL, Saeys, Y, Pasparakis, M, Bertrand, MJM, van Loo, G. OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis Cell Rep 30, 2237-2247, 2020. (Epub 2020 Feb 18)
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Vroman, H, van Uden, D, Bergen, IM, van Hulst, JAC, Lukkes, M, van Loo, G, Clausen, BE, Boon, L, Lambrecht, BN, Hammad, H, Hendriks, RW, Kool, M. Tnfaip3 expression in pulmonary conventional type 1 Langerin-expressing dendritic cells regulates T helper 2-mediated airway inflammation in mice Allergy 75, 2587-2598, 2020. (Epub 2020 Apr 23)
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Wang, B, Van Herck, S, Chen, Y, Bai, X, Zhong, Z, Deswarte, K, Lambrecht, BN, Sanders, NN, Lienenklaus, S, Scheeren, HW, David, SA, Kiessling, F, Lammers, T, De Geest, BG, Shi, Y. Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles J Am Chem Soc 142, 12133-12139, 2020. (Epub 2020 Jun 11)
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Wendrich, JR, Yang, B, Vandamme, N, Verstaen, K, Smet, W, Van de Velde, C, Minne, M, Wybouw, B, Mor, E, Arents, HE, Nolf, J, Van Duyse, J, Van Isterdael, G, Maere, S, Saeys, Y, De Rybel, B. Vascular transcription factors guide plant epidermal responses to limiting phosphate conditions Science 370, eaay4970eaay4970, 2020. (Epub 2020 Sep 17)
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Wiernicki, B, Dubois, H, Tyurina, YY, Hassannia, B, Bayir, H, Kagan, VE, Vandenabeele, P, Wullaert, A, Vanden Berghe, T. Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis Cell Death Dis 11, 922, 2020. (Epub 2020 Oct 27)
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Yang, J, Antin, P, Berx, G, Blanpain, C, Brabletz, T, Bronner, M, Campbell, K, Cano, A, Casanova, J, Christofori, G, Dedhar, S, Derynck, R, Ford, HL, Fuxe, J, Garcia de Herreros, A, Goodall, GJ, Hadjantonakis, AK, Huang, RJY, Kalcheim, C, et al.. Guidelines and definitions for research on epithelial-mesenchymal transition Nat Rev Mol Cell Biol 21, 341-352, 2020. (Epub 2020 Apr 16)
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Yao, M, Ventura, PB, Jiang, Y, Rodriguez, FJ, Wang, L, Perry, JSA, Yang, Y, Wahl, K, Crittenden, RB, Bennett, ML, Qi, L, Gong, CC, Li, XN, Barres, BA, Bender, TP, Ravichandran, KS, Janes, KA, Eberhart, CG, Zong, H. Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth Cell 180, 502-520, 2020. (Epub 2020 Jan 23)
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Ydens, E, Amann, L, Asselbergh, B, Scott, CL, Martens, L, Sichien, D, Mossad, O, Blank, T, De Prijck, S, Low, D, Masuda, T, Saeys, Y, Timmerman, V, Stumm, R, Ginhoux, F, Prinz, M, Janssens, S, Guilliams, M. Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury Nat Neurosci 23, 676-689, 2020. (Epub 2020 Apr 13)
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Amaral, AC, Saavedra, PHV, Oliveira Souza, AC, de Melo, MT, Tedesco, AC, Morais, PC, Soares Felipe, MS, Bocca, AL. Miconazole loaded chitosan-based nanoparticles for local treatment of vulvovaginal candidiasis fungal infections Colloids Surf B Biointerfaces 174, 409-415, 2019. (Epub 2019 Feb 1)
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Andries, V, De Keuckelaere, E, Staes, K, Hochepied, T, Taminau, J, Lemeire, K, Birembaut, P, Berx, G, van Roy, F. A new mouse model to study the role of ectopic Nanos3 expression in cancer BMC Cancer 19, 598, 2019. (Epub 2019 Jun 17)
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Antonioli, L, Blandizzi, C, Pacher, P, Guilliams, M, Hasko, G. Rethinking Communication in the Immune System: The Quorum Sensing Concept Trends Immunol 40, 88-97, 2019. (Epub 2019 Jan 2)
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Arandjelovic, S, Perry, JSA, Lucas, CD, Penberthy, KK, Kim, TH, Zhou, M, Rosen, DA, Chuang, TY, Bettina, AM, Shankman, LS, Cohen, AH, Gaultier, A, Conrads, TP, Kim, M, Elliott, MR, Ravichandran, KS. A noncanonical role for the engulfment gene ELMO1 in neutrophils that promotes inflammatory arthritis Nat Immunol 20, 141-151, 2019. (Epub 2019 Jan 14)
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Ballegeer, M, Vandewalle, J, Eggermont, M, Van Isterdael, G, Dejager, L, De Bus, L, Decruyenaere, J, Vandenbroucke, RE, Libert, C. Overexpression of Gilz Protects Mice Against Lethal Septic Peritonitis Shock 52, 208-214, 2019. (Epub 2018 Aug 17)
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Baraliakos, X, Braun, J, Deodhar, A, Poddubnyy, D, Kivitz, A, Tahir, H, Van den Bosch, F, Delicha, EM, Talloczy, Z, Fierlinger, A. Long-term efficacy and safety of secukinumab 150 mg in ankylosing spondylitis: 5-year results from the phase III MEASURE 1 extension study RMD Open 5, e001005, 2019. (Epub 2019 Sep 3)
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Beltran, S, Nassif, M, Vicencio, E, Arcos, J, Labrador, L, Cortes, BI, Cortez, C, Bergmann, CA, Espinoza, S, Hernandez, MF, Matamala, JM, Bargsted, L, Matus, S, Rojas-Rivera, D, Bertrand, MJM, Medinas, DB, Hetz, C, Manque, PA, Woehlbier, U. Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis Mol Neurodegener 14, 14, 2019. (Epub 2019 Mar 27)
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Beyens, A, Van Meensel, K, Pottie, L, De Rycke, R, De Bruyne, M, Baeke, F, Hoebeke, P, Plasschaert, F, Loeys, B, De Schepper, S, Symoens, S, Callewaert, B. Defining the Clinical, Molecular and Ultrastructural Characteristics in Occipital Horn Syndrome: Two New Cases and Review of the Literature Genes (Basel) 10, 528, 2019. (Epub 2019 Jul 12)
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Bibli, SI, Papapetropoulos, A, Iliodromitis, EK, Daiber, A, Randriamboavonjy, V, Steven, S, Brouckaert, P, Chatzianastasiou, A, Kypreos, KE, Hausenloy, DJ, Fleming, I, Andreadou, I. Nitroglycerin limits infarct size through S-nitrosation of Cyclophilin D: A novel mechanism for an old drug Cardiovasc Res 115, 625-636, 2019. (Epub 2018 Aug 27)
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Bieniasz-Krzywiec, P, Martin-Perez, R, Ehling, M, Garcia-Caballero, M, Pinioti, S, Pretto, S, Kroes, R, Aldeni, C, Di Matteo, M, Prenen, H, Tribulatti, MV, Campetella, O, Smeets, A, Noel, A, Floris, G, Van Ginderachter, JA, Mazzone, M. Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer Cell Metab 30, 917-936, 2019. (Epub 2019 Aug 19)
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Boeltz, S, Amini, P, Anders, HJ, Andrade, F, Bilyy, R, Chatfield, S, Cichon, I, Clancy, DM, Desai, J, et al., Maueroder, C, et al. , Vanden Berghe, T, Vandenabeele, P, Hahn, J, Hidalgo, A, Hoffmann, MH, Kaplan, MJ, Knight, JS, Kolaczkowska, E, Kubes, P, et al.. To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps Cell Death Differ 26, 395-408, 2019. (Epub 2019 Jan 8)
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Bolli, E, D'Huyvetter, M, Murgaski, A, Berus, D, Stange, G, Clappaert, EJ, Arnouk, S, Pombo Antunes, AR, Krasniqi, A, Lahoutte, T, Goncalves, A, Vuylsteke, M, Raes, G, Devoogdt, N, Movahedi, K, Van Ginderachter, JA. Stromal-targeting radioimmunotherapy mitigates the progression of therapy-resistant tumors J Control Release 314, 1-11, 2019. (Epub 2019 Oct 15)
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Bonnardel, J, T'Jonck, W, Gaublomme, D, Browaeys, R, Scott, CL, Martens, L, Vanneste, B, De Prijck, S, Nedospasov, SA, Kremer, A, Van Hamme, E, Borghgraef, P, Toussaint, W, De Bleser, P, Mannaerts, I, Beschin, A, van Grunsven, LA, Lambrecht, BN, Taghon, T, et al.. Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche Immunity 51, 638-654, 2019. (Epub 2019 Sep 24)
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Bougarne, N, Mylka, V, Ratman, D, Beck, IM, Thommis, J, De Cauwer, L, Tavernier, J, Staels, B, Libert, C, De Bosscher, K. Mechanisms Underlying the Functional Cooperation Between PPARalpha and GRalpha to Attenuate Inflammatory Responses Front Immunol 10, 1769, 2019. (Epub 2019 Aug 9)
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Braun, J, Haibel, H, de Hooge, M, Landewe, R, Rudwaleit, M, Fox, T, Readie, A, Richards, HB, Porter, B, Martin, R, Poddubnyy, D, Sieper, J, van der Heijde, D. Spinal radiographic progression over 2 years in ankylosing spondylitis patients treated with secukinumab: a historical cohort comparison Arthritis Res Ther 21, 142, 2019. (Epub 2019 Jun 7)
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Broos, K, Lecocq, Q, Keersmaecker, B, Raes, G, Corthals, J, Lion, E, Thielemans, K, Devoogdt, N, Keyaerts, M, Breckpot, K. Single Domain Antibody-Mediated Blockade of Programmed Death-Ligand 1 on Dendritic Cells Enhances CD8 T-cell Activation and Cytokine Production Vaccines (Basel) 7, 85, 2019. (Epub 2019 Aug 7)
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Broos, K, Lecocq, Q, Xavier, C, Bridoux, J, Nguyen, TT, Corthals, J, Schoonooghe, S, Lion, E, Raes, G, Keyaerts, M, Devoogdt, N, Breckpot, K. Evaluating a Single Domain Antibody Targeting Human PD-L1 as a Nuclear Imaging and Therapeutic Agent Cancers (Basel) 11, 6, 2019. (Epub 2019 Jun 21)
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Bruger, AM, Dorhoi, A, Esendagli, G, Barczyk-Kahlert, K, van der Bruggen, P, Lipoldova, M, Perecko, T, Santibanez, J, Saraiva, M, Van Ginderachter, JA, Brandau, S. How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions Cancer Immunol Immunother 68, 631-644, 2019. (Epub 2018 May 21)
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Cambre, I, Gaublomme, D, Schryvers, N, Lambrecht, S, Lories, R, Venken, K, Elewaut, D. Running promotes chronicity of arthritis by local modulation of complement activators and impairing T regulatory feedback loops Ann Rheum Dis 78, 787-795, 2019. (Epub 2019 Mar 30)
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Chuang, YT, Leung, K, Chang, YJ, DeKruyff, RH, Savag, PB, Cruse, R, Benoit, C, Elewaut, D, Baumgarth, N, Umetsu, DT. A Natural Killer T cell subset that protects against airway hyperreactivity J Allergy Clin Immunol 143, 565-576, 2019. (Epub 2018 May 28)
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Claudepierre, P, Van den Bosch, F, Sarzi-Puttini, P, Vastesaeger, N, Govoni, M, Kachroo, S. Treatment with golimumab or infliximab reduces health resource utilization and increases work productivity in patients with ankylosing spondylitis in the QUO-VADIS study, a large, prospective real-life cohort Int J Rheum Dis 22, 995-1001, 2019. (Epub 2019 Apr 15)
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Cochet, F, Facchini, FA, Zaffaroni, L, Billod, JM, Coelho, H, Holgado, A, Braun, H, Beyaert, R, Jerala, R, Jimenez-Barbero, J, Martin-Santamaria, S, Peri, F. Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties Sci Rep 9, 919, 2019. (Epub 2019 Jan 29)
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