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Van Hove, H, Martens, L, Scheyltjens, I, De Vlaminck, K, Pombo Antunes, AR, De Prijck, S, Vandamme, N, De Schepper, S, Van Isterdael, G, Scott, CL, Aerts, J, Berx, G, Boeckxstaens, GE, Vandenbroucke, RE, Vereecke, L, Moechars, D, Guilliams, M, Van Ginderachter, JA, Saeys, Y, Movahedi, K.
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
Nat Neurosci 22, 10211035, 2019. (Epub 2019 May 6)

Van Looveren, K, Van Boxelaere, M, Callaerts-Vegh, Z, Libert, C.
Cognitive dysfunction in mice lacking proper glucocorticoid receptor dimerization
PLoS One 14, e0226753, 2019. (Epub 2019 Dec 23)

Van Malderen, SJM, Van Acker, T, Laforce, B, De Bruyne, M, de Rycke, R, Asaoka, T, Vincze, L, Vanhaecke, F.
Three-dimensional reconstruction of the distribution of elemental tags in single cells using laser ablation ICP-mass spectrometry via registration approaches
Anal Bioanal Chem 411, 4849-4859, 2019. (Epub 2019 Feb 21)

Varasteh, Z, Mohanta, S, Li, Y, Lopez Armbruster, N, Braeuer, M, Nekolla, SG, Habenicht, A, Sager, HB, Raes, G, Weber, W, Hernot, S, Schwaiger, M.
Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using (68)Ga-NOTA-anti-MMR nanobody: non-invasive imaging of atherosclerotic plaques
EJNMMI Res 9, 5, 2019. (Epub 2019 Jan 21)

Varkas, G, Ribbens, C, Louis, E, Van den Bosch, F, Lories, R, Vermeire, S, Elewaut, D, De Vos, M.
Expert consensus: practical algorithms for management of inflammatory bowel disease patients presenting with back pain or peripheral arthropathies
Aliment Pharmacol Ther 50, 1204-1213, 2019. (Epub 2019 Oct 25)

Veale, DJ, McGonagle, D, McInnes, IB, Krueger, JG, Ritchlin, CT, Elewaut, D, Kanik, KS, Hendrikx, T, Berstein, G, Hodge, J, Telliez, JB.
The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis
Rheumatology (Oxford) 58, 197-205, 2019. (Epub 2018 Apr 3)

Venken, K, Jacques, P, Mortier, C, Labadia, ME, Decruy, T, Coudenys, J, et al., Van Gassen, S, Martens, L, Smith, D, Harcken, C, Wahle, J, Wang, CT, Verheugen, E, Schryvers, N, Varkas, G, Cypers, H, et al.,Van den Bosch, F, Saeys, Y, Nabozny, G, Elewaut D.
RORgammat inhibition selectively targets IL-17 producing iNKT and gammadelta-T cells enriched in Spondyloarthritis patients
Nat Commun 10, 9, 2019. (Epub 2019 Jan 2)

Verschueren, KHG, Blanchet, C, Felix, J, Dansercoer, A, De Vos, D, Bloch, Y, Van Beeumen, J, Svergun, D, Gutsche, I, Savvides, SN, Verstraete, K.
Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle
Nature 568, 571-575, 2019. (Epub 2019 Apr 3)

Vetters, J, van Helden, MJ, Wahlen, S, Tavernier, SJ, Martens, A, Fayazpour, F, Vergote, K, Vanheerswynghels, M, Deswarte, K, Van Moorleghem, J, De Prijck, S, Takahashi, N, Vandenabeele, P, Boon, L, van Loo, G, Vivier, E, Lambrecht, BN, Janssens, S.
The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF
J Exp Med 216, 2010-2023, 2019. (Epub 2019 Jul 11)

Vluymans, S, Mac Parthalain, N, Cornelis, C, Saeys, Y.
Weight selection strategies for ordered weighted average based fuzzy rough sets
Information Sciences 501, 155-171, 2019. (Epub 2019 May 29)

Voet, S, Prinz, M, van Loo, G.
Microglia in Central Nervous System Inflammation and Multiple Sclerosis Pathology
Trends Mol Med 25, 112-123, 2019. (Epub 2018 Dec 18)

Voet, S, Srinivasan, S, Lamkanfi, M, van Loo, G.
Inflammasomes in neuroinflammatory and neurodegenerative diseases
EMBO Mol Med 11, e10248, 2019. (Epub 2019 Apr 23)

Vriens, K, Christen, S, Parik, S, Broekaert, D, Yoshinaga, K, Talebi, A, Dehairs, J, Escalona-Noguero, C, Schmieder, R, Cornfield, T, Charlton, C, Romero-Perez, L, Rossi, M, Rinaldi, G, Orth, MF, Boon, R, Kerstens, A, Kwan, SY, Faubert, B, et al..
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity
Nature 566, 403406, 2019. (Epub 2019 Feb 6)

Webb, LV, Barbarulo, A, Huysentruyt, J, Vanden Berghe, T, Takahashi, N, Ley, S, Vandenabeele, P, Seddon, B.
Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-kappaB
Immunity 50, 348-361, 2019. (Epub 2019 Jan 23)

Weber, LM, Saelens, W, Cannoodt, R, Soneson, C, Hapfelmeier, A, Gardner, PP, Boulesteix, AL, Saeys, Y, Robinson, MD.
Essential guidelines for computational method benchmarking
Genome Biol 20, 125, 2019. (Epub 2019 Jun 20)

Willebrand, R, Hamad, I, Van Zeebroeck, L, Kiss, M, Bruderek, K, Geuzens, A, Swinnen, D, Corte-Real, BF, Marko, L, Lebegge, E, Laoui, D, Kemna, J, Kammertoens, T, Brandau, S, Van Ginderachter, JA, Kleinewietfeld, M.
High Salt Inhibits Tumor Growth by Enhancing Anti-tumor Immunity
Front Immunol 10, 1141, 2019. (Epub 2019 Jun 4)

Xavier, C, Blykers, A, Laoui, D, Bolli, E, Vaneyken, I, Bridoux, J, Baudhuin, H, Raes, G, Everaert, H, Movahedi, K, Van Ginderachter, JA, Devoogdt, N, Caveliers, V, Lahoutte, T, Keyaerts, M.
Clinical Translation of [(68)Ga]Ga-NOTA-anti-MMR-sdAb for PET/CT Imaging of Protumorigenic Macrophages
Mol Imaging Biol 21, 898-906, 2019. (Epub 2019 Jan 22)

Zachariassen, LF, Hansen, AK, Krych, L, Nielsen, DS, Holm, TL, Tougaard, P, Hansen, CHF.
Cesarean section increases sensitivity to oxazolone-induced colitis in C57BL/6 mice
Mucosal Immunol 12, 1348-1357, 2019. (Epub 2019 Sep 25)

Zhang, Z, Li, H, Kasmi, S, Van Herck, S, Deswarte, K, Lambrecht, B, Hoogenboom, R, Nuhn, L, de Geest, B.
A Synthetic Transiently Thermoresponsive Homopolymer with UCST Behaviour within a Physiologically Relevant Window
Angew Chem Int Ed Engl 58, 7866-7872, 2019. (Epub 2019 Mar 29)

Zheng, F, Luo, S, Ouyang, Z, Zhou, J, Mo, H, Schoonooghe, S, Muyldermans, S, De Baetselier, P, Raes, G, Wen, Y.
NIRF-Molecular Imaging with Synovial Macrophages-Targeting Vsig4 Nanobody for Disease Monitoring in a Mouse Model of Arthritis
Int J Mol Sci 20, 3347, 2019. (Epub 2019 Jul 8)

Zhong, Z, Portela Catani, JP, Mc Cafferty, S, Couck, L, Van Den Broeck, W, Gorle, N, Vandenbroucke, RE, Devriendt, B, Ulbert, S, Cnops, L, Michels, J, Arien, KK, Sanders, NN.
Immunogenicity and Protection Efficacy of a Naked Self-Replicating mRNA-Based Zika Virus Vaccine
Vaccines (Basel) 7, 96, 2019. (Epub 2019 Aug 23)

Adanitsch, F, Shi, J, Shao, F, Beyaert, R, Heine, H, Zamyatina, A.
Synthetic glycan-based TLR4 agonists targeting caspase-4/11 for the development of adjuvants and immunotherapeutics
Chem Sci 9, 3957-3963, 2018. (Epub 2018 Mar 15)

Alissafi, T, Kourepini, E, Simoes, DCM, Paschalidis, N, Aggelakopoulou, M, Sparwasser, T, Boon, L, Hammad, H, Lambrecht, BN, Panoutsakopoulou, V.
Osteopontin Promotes Protective Antigenic Tolerance against Experimental Allergic Airway Disease
J Immunol 200, 1270-1282, 2018. (Epub 2018 Jan 12)

Andersson, P, Yang, Y, Hosaka, K, Zhang, Y, Fischer, C, Braun, H, Liu, S, Yu, G, Liu, S, Beyaert, R, Chang, M, Li, Q, Cao, Y.
Molecular mechanisms of IL-33-mediated stromal interactions in cancer metastasis
JCI Insight 3, e122375, 2018. (Epub 2018 Oct 18)

Annibaldi, A, Wicky John, S, Vanden Berghe, T, Swatek, KN, Ruan, J, Liccardi, G, Bianchi, K, Elliott, PR, Choi, SM, Van Coillie, S, Bertin, J, Wu, H, Komander, D, Vandenabeele, P, Silke, J, Meier, P.
Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2
Mol Cell 69, 566-580, 2018. (Epub 2018 Feb 15)

Antonioli, L, Blandizzi, C, Pacher, P, Guilliams, M, Hasko, G.
Quorum sensing in the immune system
Nat Rev Immunol 18, 537-538, 2018. (Epub 2018 Jul 13)

Bala, G, Baudhuin, H, Remory, I, Gillis, K, Debie, P, Krasniqi, A, Lahoutte, T, Raes, G, Devoogdt, N, Cosyns, B, Hernot, S.
Evaluation of [(99m)Tc]Radiolabeled Macrophage Mannose Receptor-Specific Nanobodies for Targeting of Atherosclerotic Lesions in Mice
Mol Imaging Biol 20, 260-267, 2018. (Epub 2017 Sep 5)

Ballegeer, M, Van Looveren, K, Timmermans, S, Eggermont, M, Vandevyver, S, Thery, F, Dendoncker, K, Souffriau, J, Vandewalle, J, Van Wyngene, L, De Rycke, R, Takahashi, N, Vandenabeele, P, Tuckermann, J, Reichardt, HM, Impens, F, Beyaert, R, De Bosscher, K, Vandenbroucke, RE, et al..
Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice
J Clin Invest 128, 3265-3279, 2018. (Epub 2018 May 10)

Berings, M, Gevaert, P, De Ruyck, N, Derycke, L, Holtappels, G, Pilette, C, Bachert, C, Lambrecht, BN, Dullaers, M.
FcepsilonRI expression and IgE binding by dendritic cells and basophils in allergic rhinitis and upon allergen immunotherapy
Clin Exp Allergy 48, 970-980, 2018. (Epub 2018 Apr 22)

Beute, J, Lukkes, M, Koekoek, EP, Nastiti, H, Ganesh, K, de Bruijn, MJ, Hockman, S, van Nimwegen, M, Braunstahl, GJ, Boon, L, Lambrecht, BN, Manganiello, VC, Hendriks, RW, KleinJan, A.
A pathophysiological role of PDE3 in allergic airway inflammation
JCI Insight 3, e94888, 2018. (Epub 2018 Jan 25)

Beyaert, R, Libert, C.
How Good Roommates Can Protect against Microbial Sepsis
Cell Host Microbe 23, 283-285, 2018. (Epub 2018 Mar 14)

Bhosale, R, Boudolf, V, Cuevas, F, Lu, R, Eekhout, T, Hu, Z, Van Isterdael, G, Lambert, GM, Xu, F, Nowack, MK, Smith, RS, Vercauteren, I, De Rycke, R, Storme, V, Beeckman, T, Larkin, JC, Kremer, A, Hofte, H, Galbraith, DW, et al..
A Spatiotemporal DNA Endoploidy Map of the Arabidopsis Root Reveals Roles for the Endocycle in Root Development and Stress Adaptation
Plant Cell 30, 2330-2351, 2018. (Epub 2018 Oct)

Boeck, C, Pfister, S, Burkle, A, Vanhooren, V, Libert, C, Salinas-Manrique, J, Dietrich, DE, Kolassa, IT, Karabatsiakis, A.
Alterations of the serum N-glycan profile in female patients with Major Depressive Disorder
J Affect Disord 234, 139-147, 2018. (Epub 2018 Feb 27)

Bogaert, DJ, Kuehn, HS, Bonroy, C, Calvo, KR, Dehoorne, J, Vanlander, AV, De Bruyne, M, Cytlak, U, Bigley, V, De Baets, F, De Baere, E, Rosenzweig, SD, Haerynck, F, Dullaers, M.
A novel IKAROS haploinsufficiency kindred with unexpectedly late and variable B-cell maturation defects
J Allergy Clin Immunol 141, 432-435, 2018. (Epub 2017 Sep 18)

Bogie, JF, Boelen, E, Louagie, E, Delputte, P, Elewaut, D, van Horssen, J, Hendriks, JJ, Hellings, N.
CD169 is a marker for highly pathogenic phagocytes in multiple sclerosis
Multiple Sclerosis Journal 24, 290-300, 2018. (Epub 2017 Mar 1)

Bonelli, S, Geeraerts, X, Bolli, E, Keirsse, J, Kiss, M, Pombo Antunes, AR, Van Damme, H, De Vlaminck, K, Movahedi, K, Laoui, D, Raes, G, Van Ginderachter, JA.
Beyond the M-CSF receptor: novel therapeutic targets in tumor-associated macrophages
FEBS J 285, 777-787, 2018. (Epub 2017 Aug 20)

Borday, C, Parain, K, Thi Tran, H, Vleminckx, K, Perron, M, Monsoro-Burq, AH.
An atlas of Wnt activity during embryogenesis in Xenopus tropicalis
PLoS One 13, e0193606, 2018. (Epub 2018 Apr 19)

Borghi, A, Haegman, M, Fischer, R, Carpentier, I, Bertrand, MJM, Libert, C, Afonina, IS, Beyaert, R.
The E3 ubiquitin ligases HOIP and cIAP1 are recruited to the TNFR2 signaling complex and mediate TNFR2-induced canonical NF-kappaB signaling
Biochem Pharmacol 153, 292-298, 2018. (Epub 2018 Jan 26)

Borio, A, Holgado, A, Beyaert, R, Heine, H, Zamyatina, A.
Disaccharide-based Anionic Amphiphiles as Potent Inhibitors of LPS-induced Inflammation
ChemMedChem 13, 2317-2331, 2018. (Epub 2018 Oct 1)

Bosteels, C, Lambrecht, BN, Hammad, H.
Isolation of Conventional Murine Lung Dendritic Cell Subsets
Curr Protoc Immunol 120, 3.7B.13.7B.16, 2018. (Epub 2018 Feb 21)

Bougarne, N, Weyers, B, Desmet, SJ, Deckers, J, Ray, DW, Staels, B, De Bosscher, K.
Molecular Actions of PPARalpha in Lipid Metabolism and Inflammation
Endocr Rev 39, 760-802, 2018. (Epub 2018 Oct 1)

Bouhy, D, Juneja, M, Katona, I, Holmgren, A, Asselbergh, B, De Winter, V, Hochepied, T, Goossens, S, Haigh, JJ, Libert, C, Ceuterick-de Groote, C, Irobi, J, Weis, J, Timmerman, V.
A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8
Acta Neuropathol 135, 131-148, 2018. (Epub 2017 Aug 5)

Braun, H, Afonina, IS, Mueller, C, Beyaert, R.
Dichotomous function of IL-33 in health and disease: from biology to clinical implications
Biochem Pharmacol 148, 238-252, 2018. (Epub 2018 Jan 5)

Broos, K, Lecocq, Q, Raes, G, Devoogdt, N, Keyaerts, M, Breckpot, K.
Noninvasive imaging of the PD-1:PD-L1 immune checkpoint: Embracing nuclear medicine for the benefit of personalized immunotherapy
Theranostics 8, 3559-3570, 2018. (Epub 2018 Jun 7)

Burmester, GR, Kremer, JM, Van den Bosch, F, Kivitz, A, Bessette, L, Li, Y, Zhou, Y, Othman, AA, Pangan, AL, Camp, HS.
Safety and efficacy of upadacitinib in patients with rheumatoid arthritis and inadequate response to conventional synthetic disease-modifying anti-rheumatic drugs (SELECT-NEXT): a randomised, double-blind, placebo-controlled phase 3 trial
Lancet 391, 2503-2512, 2018. (Epub 2018 Jun 23)

Caljon, G, Mabille, D, Stijlemans, B, De Trez, C, Mazzone, M, Tacchini-Cottier, F, Malissen, M, Van Ginderachter, J.A., Magez, S, De Baetselier, P, Van Den Abbeele, J.
Neutrophils enhance early Trypanosoma brucei infection onset
Sci Rep 8, 11203, 2018. (Epub 2018 Jul 25)

Cambre, I, Gaublomme, D, Burssens, A, Jacques, P, Schryvers, N, De Muynck, A, Meuris, L, Lambrecht, S, Carter, S, de Bleser, P, Saeys, Y, Van Hoorebeke, L, Kollias, G, Mack, M, Simoens, P, Lories, R, Callewaert, N, Schett, G, Elewaut, D.
Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis
Nat Commun 9, 4613, 2018. (Epub 2018 Nov 5)

Cannoodt, R, Ruyssinck, J, Ramon, J, De Preter, K, Saeys, Y.
IncGraph: Incremental graphlet counting for topology optimisation
PLoS One 13, e0195997, 2018. (Epub 2018 Apr 26)

Carron, P, Varkas, G, Renson, T, Colman, R, Elewaut, D, Van den Bosch, F.
High rate of drug-free remission after induction therapy with golimumab in early peripheral spondyloarthritis
Arthritis Rheumatol 70, 1769-1777, 2018. (Epub 2018 May 27)

Casillo, A, Ziaco, M, Lindner, B, Parrilli, E, Schwudke, D, Holgado, A, Beyaert, R, Lanzetta, R, Tutino, ML, Corsaro, MM.
Lipid A structural characterization from the LPS of the Siberian psychro-tolerant Psychrobacter arcticus 273-4 grown at low temperature
Extremophiles 22, 955-963, 2018. (Epub 2018 Aug 20)

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