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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Carron, P, Lambert, B, Van Praet, L, De Vos, F, Varkas, G, Jans, L, Elewaut, D, Van den Bosch, F. Scintigraphic detection of TNF-driven inflammation by radiolabelled certolizumab pegol in patients with rheumatoid arthritis and spondyloarthritis RMD Open 2, e000265, 2016. (Epub 2016 Jun 24) 
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Catrysse, L, Farhang Ghahremani, M, Vereecke, L, Youssef, SA, Mc Guire, C, Sze, M, Weber, A, Heikenwalder, M, de Bruin, A, Beyaert, R, van Loo, G. A20 prevents chronic liver inflammation and cancer by protecting hepatocytes from death Cell Death Dis 7, e2250, 2016. (Epub 2016 Jun 2)
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Cleenewerck, M, Grootaert, MO, Gladysz, R, Adriaenssens, Y, Roelandt, R, Joossens, J, Lambeir, AM, De Meyer, GR, Declercq, W, Augustyns, K, Martinet, W, Van der Veken, P. Inhibitor screening and enzymatic activity determination for autophagy target Atg4B using a gel electrophoresis-based assay Eur J Med Chem 123, 631-638, 2016. (Epub 2016 Jul 31)
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Conrad, M, Angeli, JP, Vandenabeele, P, Stockwell, BR. Regulated necrosis: disease relevance and therapeutic opportunities Nat Rev Drug Discov 15, 348-366, 2016. (Epub 2016 Jan 18)
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Cypers, H, Varkas, G, Beeckman, S, Debusschere, K, Vogl, T, Roth, J, Drennan, MB, Lavric, M, Foell, D, Cuvelier, CA, De Vos, M, Delanghe, J, Van den Bosch, F, Elewaut, D. Elevated calprotectin levels reveal bowel inflammation in spondyloarthritis Ann Rheum Dis 75, 1357-1362, 2016. (Epub 2015 Dec 23)
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Davison, A, McDowell, Gary S, Holden, Jennifer M, Johnson, Harriet F, Koutsovoulos, Georgios D, Liu, MM, Hulpiau, P, Van Roy, F, Wade, Christopher M, Banerjee, R, Yang, F, Chiba, S, Davey, John W, Jackson, Daniel J, Levin, M, Blaxter, Mark L. Formin Is Associated with Left-Right Asymmetry in the Pond Snail and the Frog Current Biology 26, 1-7, 2016. (Epub 2016 Mar 7)
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De Beuckelaer, A, Pollard, C, Van Lint, S, Roose, K, Van Hoecke, L, Naessens, T, Udhayakumar, VK, Smet, M, Sanders, N, Lienenklaus, S, Saelens, X, Weiss, S, Vanham, G, Grooten, J, De Koker, S. Type I interferons interfere with the capacity of mRNA lipoplex vaccines to elicit cytolytic T cell responses Mol Ther 24, 2012-2020, 2016. (Epub 2016 Aug 10)
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Debeuf, N, Haspeslagh, E, van Helden, M, Hammad, H, Lambrecht, BN. Mouse Models of Asthma Curr Protoc Mouse Biol 6, 169-184, 2016. (Epub 2016 Jun 1)
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De Bock, M, Van Haver, V, Vandenbroucke, RE, Decrock, E, Wang, N, Leybaert, L. Into rather unexplored terrain-transcellular transport across the blood-brain barrier Glia 64, 1097-1123, 2016. (Epub 2016 Feb 8)
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De Bosscher, K, Beck, IM, Ratman, D, Berghe, WV, Libert, C. Activation of the Glucocorticoid Receptor in Acute Inflammation: the SEDIGRAM Concept Trends Pharmacol Sci 37, 4-16, 2016. (Epub 2015 Oct 22)
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Debusschere, K, Lories, RJ, Elewaut, D. MAIT cells: not just another brick in the wall Ann Rheum Dis 75, 2057-2059, 2016. (Epub 2016 Jul 29)
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De Coen, R, Vanparijs, N, Risseeuw, MD, Lybaert, L, Louage, B, De Koker, S, Kumar, V, Grooten, J, Taylor, L, Ayres, N, Van Calenbergh, S, Nuhn, L, De Geest, BG. pH-degradable mannosylated nanogels for dendritic cell targeting Biomacromolecules 17, 2479-2488, 2016. (Epub 2016 May 26)
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De Groote, P, Grootjans, S, Lippens, S, Eichperger, C, Leurs, K, Kahr, I, Tanghe, G, Bruggeman, I, De Schamphelaire, W, Urwyler, C, Vandenabeele, P, Haustraete, J, Declercq, W. Generation of a new Gateway-compatible inducible lentiviral vector platform allowing easy derivation of co-transduced cells Biotechniques 60, 252-259, 2016. (Epub 2016 May 1)
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de Kleer, IM, Kool, M, de Bruijn, MJ, Willart, M, van Moorleghem, J, Schuijs, MJ, Plantinga, M, Beyaert, R, Hams, E, Fallon, PG, Hammad, H, Hendriks, RW, Lambrecht, BN. Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung Immunity 45, 1285-1298, 2016. (Epub 2016 Dec 5)
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Demeestere, D, Dejonckheere, E, Steeland, S, Hulpiau, P, Haustraete, J, Devoogdt, N, Wichert, R, Becker-Pauly, C, Van Wonterghem, E, Dewaele, S, Van Imschoot, G, Aerts, J, Arckens, L, Saeys, Y, Libert, C, Vandenbroucke, RE. Development and validation of a small single domain antibody that effectively inhibits matrix metalloproteinase 8 Mol Ther 24, 890-902, 2016. (Epub 2016 Jan 18)
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Demeyer, A, Staal, J, Beyaert, R. Targeting MALT1 Proteolytic Activity in Immunity, Inflammation and Disease: Good or Bad? Trends Mol Med 22, 135-150, 2016. (Epub 2016 Jan 16)
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De Mits, S, Lenaerts, J, Vander Cruyssen, B, Mielants, H, Westhovens, R, Durez, P, Elewaut, D, Be-Raise study, g. A Nationwide Survey on Patient's versus Physician s Evaluation of Biological Therapy in Rheumatoid Arthritis in Relation to Disease Activity and Route of Administration: The Be-Raise Study PLoS One 11, e0166607, 2016. (Epub 2016 Nov 28)
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De Pauw, A, Massion, P, Sekkali, B, Andre, E, Dubroca, C, Kmecova, J, Bouzin, C, Friart, A, Sibille, C, Gilon, P, De Mulder, D, Esfahani, H, Strapart, A, Martherus, R, Payen, V, Sonveaux, P, Brouckaert, P, Janssens, S, Balligand, JL. Paracrine nitric oxide induces expression of cardiac sarcomeric proteins in adult progenitor cells through soluble guanylyl cyclase/cyclic-guanosine monophosphate and Wnt/beta-catenin inhibition Cardiovasc Res 112, 478-490, 2016. (Epub 2016 Aug 12)
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De Samber, B, Niemiec, MJ, Laforce, B, Garrevoet, J, Vergucht, E, De Rycke, R, Cloetens, P, Urban, CF, Vincze, L. Probing Intracellular Element Concentration Changes during Neutrophil Extracellular Trap Formation Using Synchrotron Radiation Based X-Ray Fluorescence PLoS One 11, e0165604, 2016. (Epub 2016 Nov 3)
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De Schryver, E, Calus, L, Bonte, H, Natalie, R, Gould, H, Donovan, E, Elewaut, D, Valenta, R, Mittermann, I, Gutermuth, J, Seher, T, Schleimer, RP, Tan, BK, Derycke, L, Van Zele, T, Bachert, C, Gevaert, P. The quest for autoreactive antibodies in nasal polyps J Allergy Clin Immunol 138, 893–895e5, 2016. (Epub 2016 May 6)
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de Vasconcelos, NM, Van Opdenbosch, N, Lamkanfi, M. Inflammasomes as polyvalent cell death platforms Cell Mol Life Sci 73, 2335-2347, 2016. (Epub 2016 Apr 5)
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Dondelinger, Y, Darding, M, Bertrand, MJ, Walczak, H. Poly-ubiquitination in TNFR1-mediated necroptosis Cell Mol Life Sci 73, 2165–2176, 2016. (Epub 2016 Apr 11)
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Dondelinger, Y, Hulpiau, P, Saeys, Y, Bertrand, MJ, Vandenabeele, P. An evolutionary perspective on the necroptotic pathway Trends Cell Biol 26, 721-732, 2016. (Epub 2016 Jun 28)
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Dondelinger, Y, Vandenabeele, P, Bertrand, MJ. Regulation of RIPK1's cell death function by phosphorylation Cell Cycle 15, 5-6, 2016. (Epub 2015 Oct 30)
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Dordea, AC, Vandenwijngaert, S, Garcia, V, Tainsh, RE, Nathan, DI, Allen, K, Raher, MJ, Tainsh, LT, Zhang, FF, Lieb, WS, Mikelman, S, Kirby, A, Stevens, C, Thoonen, R, Hindle, AG, Sips, PY, Falck, JR, Daly, MJ, Brouckaert, P, et al.. Androgen-Sensitive Hypertension Associated with Soluble Guanylate Cyclase Alpha1 Deficiency Is Mediated by 20-Hete Am J Physiol Heart Circ Physiol 310, H1790-H1800, 2016. (Epub 2016 May 3)
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Drechsler, S, Lynch, MA, Novella, S, Gonzalez-Navarro, H, Hecimovic, S, Barini, E, Tucci, V, Castro, RE, Vandenbroucke, RE, Osuchowski, M, Potter, PK. With mouse age comes wisdom: a review and suggestions of relevant mouse models for age-related conditions Mech Ageing Dev 160, 54-68, 2016. (Epub 2016 Jul 20)
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Drennan, MB, Govindarajan, S, Verheugen, E, Coquet, JM, Staal, J, McGuire, C, Taghon, T, Leclercq, G, Beyaert, R, van Loo, G, Lambrecht, BN, Elewaut, D. NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20 J Exp Med 213, 1973-1981, 2016. (Epub 2016 Aug 22)
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Dubois, H, Wullaert, A, Lamkanfi, M. General Strategies in Inflammasome Biology Curr Top Microbiol Immunol 397, 1-22, 2016. (Epub 2016 Jul 27)
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Elton, L, Carpentier, I, Staal, J, Driege, Y, Haegman, M, Beyaert, R. MALT1 cleaves the E3 ubiquitin ligase HOIL-1 in activated T cells, generating a dominant negative inhibitor of LUBAC-induced NF-kappaB signaling FEBS J 283, 403-412, 2016. (Epub 2015 Nov 17)
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Exley, MA, Tsokos, GC, Mills, KH, Elewaut, D, Mulhearn, B. What rheumatologists need to know about innate lymphocytes Nat Rev Rheumatol 12, 658-668, 2016. (Epub 2016 Sep 2)
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Faura Tellez, G, Willemse, BW, Brouwer, U, Nijboer-Brinksma, S, Vandepoele, K, Noordhoek, JA, Heijink, I, de Vries, M, Smithers, NP, Postma, DS, Timens, W, Wiffen, L, van Roy, F, Holloway, JW, Lackie, PM, Nawijn, MC, Koppelman, GH. Protocadherin-1 Localization and Cell-Adhesion Function in Airway Epithelial Cells in Asthma PLoS One 11, e0163967, 2016. (Epub 2016 Oct 4)
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Favreau, M, Vanderkerken, K, Elewaut, D, Venken, K, Menu, E. Does an NKT-cell-based immunotherapeutic approach have a future in multiple myeloma? Oncotarget 7, 23128-23140, 2016. (Epub 2016 Feb 17)
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Felix, J, Kandiah, E, De Munck, S, Bloch, Y, van Zundert, GC, Pauwels, K, Dansercoer, A, Novanska, K, Read, RJ, Bonvin, AM, Vergauwen, B, Verstraete, K, Gutsche, I, Savvides, SN. Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF Nat Commun 7, 13228, 2016. (Epub 2016 Nov 7)
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Filliol, A, Piquet-Pellorce, C, Le Seyec, J, Farooq, M, Genet, V, Lucas-Clerc, C, Bertin, J, Gough, PJ, Dimanche-Boitrel, MT, Vandenabeele, P, Bertrand, MJ, Samson, M. RIPK1 protects from TNF-alpha-mediated liver damage during hepatitis Cell Death Dis 7, e2462, 2016. (Epub 2016 Nov 10)
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Filtjens, J, Keirsse, J, Van Ammel, E, Taveirne, S, Van Acker, A, Kerre, T, Taghon, T, Vandekerckhove, B, Plum, J, Van Ginderachter, JA, Leclercq, G. Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours Sci Rep 6, 30564, 2016. (Epub 2016 Jul 29)
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Folmsbee, SS, Wilcox, DR, Tyberghein, K, De Bleser, P, Tourtellotte, WG, van Hengel, J, van Roy, F, Gottardi, CJ. alphaT-catenin in restricted brain cell types and its potential connection to autism J Mol Psychiatry 4, 2, 2016. (Epub 2016 Jun 21)
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Fukaya, M, Brorsson, CA, Meyerovich, K, Catrysse, L, Delaroche, D, Vanzela, EC, Ortis, F, Beyaert, R, Nielsen, LB, Andersen, ML, Mortensen, HB, Pociot, F, van Loo, G, St Rling, J, Cardozo, AK. A20 inhibits beta-cell Apoptosis by Multiple Mechanisms and Predicts Residual beta-cell Function in Type 1 Diabetes Mol Endocrinol 30, 48-61, 2016. (Epub 2015 Dec 10)
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Garg, AD, Krysko, DV, Vandenabeele, P, Agostinis, P. Extracellular ATP and P2X7 receptor exert context-specific immunogenic effects after immunogenic cancer cell death Cell Death Dis 7, e2097, 2016. (Epub 2016 Feb 18)
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Geeraerts, E, Dekeyster, E, Gaublomme, D, Salinas-Navarro, M, De Groef, L, Moons, L. A freely available semi-automated method for quantifying retinal ganglion cells in entire retinal flatmounts Exp Eye Res 147, 105-113, 2016. (Epub 2016 Apr 20)
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Ginhoux, F, Guilliams, M. Tissue-Resident Macrophage Ontogeny and Homeostasis Immunity 44, 439-449, 2016. (Epub 2016 Mar 15)
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Ginhoux, F, Guilliams, M, Naik, SH. Editorial: Dendritic Cell and Macrophage Nomenclature and Classification Front Immunol 7, 168, 2016. (Epub 2016 May 2)
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Godar, M, Lambrecht, BN. A New aDENNDum to Genetics of Childhood Asthma Cell 164, 11-13, 2016. (Epub 2016 Jan 14)
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Godar, M, Morello, V, Sadi, A, Hultberg, A, De Jonge, N, Basilico, C, Hanssens, V, Saunders, M, Lambrecht, BN, El Khattabi, M, de Haard, H, Michieli, P, Blanchetot, C. Dual anti-idiotypic purification of a novel, native-format biparatopic anti-MET antibody with improved in vitro and in vivo efficacy Sci Rep 6, 31621, 2016. (Epub 2016 Aug 22)
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Goktuna, SI, Shostak, K, Chau, TL, Heukamp, LC, Hennuy, B, Duong, HQ, Ladang, A, Close, P, Klevernic, I, Olivier, F, Florin, A, Ehx, G, Baron, F, Vandereyken, M, Rahmouni, S, Vereecke, L, Van Loo, G, Buttner, R, Greten, F, et al.. The pro-survival IKK-related kinase IKKepsilon integrates LPS and IL-17A signaling cascades to promote Wnt-dependent tumor development in the intestine Cancer Res 76, 2587-2599, 2016. (Epub 2016 Mar 15)
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González, M, Bergmeir, C, Triguero, I, Rodriguez, Y, Benítez, JM. On the stopping criteria for k-Nearest Neighbor in positive unlabeled time series classification problems Information Sciences 328, 42-59, 2016. (Epub 2015 Aug 22)
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Goossens, S, Van Vlierberghe, P. Overcoming Steroid Resistance in T Cell Acute Lymphoblastic Leukemia PLoS Med 13, e1002208, 2016. (Epub 2016 Dec 20)
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Gorlé, N, Van Cauwenberghe, C, Libert, C, Vandenbroucke, RE. The effect of aging on brain barriers and the consequences for Alzheimer's disease development Mamm Genome 27, 407-420, 2016. (Epub 2016 May 3)
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Grine, L, Libert, C, Vandenbroucke, R. Comment on "Tumour necrosis factor alpha plays a significant role in the Aldara-induced skin inflammation in mice" Br J Dermatol 174, 1419-1419, 2016. (Epub 2016 Feb 6)
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Grine, L, Steeland, S, Van Ryckeghem, S, Ballegeer, M, Lienenklaus, S, Weiss, S, Sanders, NN, Vandenbroucke, RE, Libert, C. Topical imiquimod yields systemic effects due to unintended oral uptake Sci Rep 6, 20134, 2016. (Epub 2016 Jan 28)
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Grootaert, MO, Schrijvers, DM, Van Spaendonk, H, Breynaert, A, Hermans, N, Van Hoof, VO, Takahashi, N, Vandenabeele, P, Kim, SH, De Meyer, GR, Martinet, W. NecroX-7 reduces necrotic core formation in atherosclerotic plaques of Apoe knockout mice Atherosclerosis 252, 166-174, 2016. (Epub 2016 Sep)
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