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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Lybaert, L, De Vlieghere, E, De Rycke, R, Vanparijs, N, De Wever, O, De Koker, S, De Geest, BG. Bio-Hybrid Tumor Cell-Templated Capsules: A Generic Formulation Strategy for Tumor Associated Antigens in View of Immune Therapy Advanced Functional Materials 24, 7139-7150, 2014. (Epub 2014 Sep 11) 
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Maes, H, Van Eygen, S, Krysko, DV, Vandenabeele, P, Nys, K, Rillaerts, K, Garg, AD, Verfaillie, T, Agostinis, P. BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton Cell Death Dis 5, e1127, 2014. (Epub 2014 Mar 13)
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Mc Guire, C, Elton, L, Wieghofer, P, Staal, J, Voet, S, Demeyer, A, Nagel, D, Krappmann, D, Prinz, M, Beyaert, R, van Loo, G. Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis J Neuroinflamm 11, 124, 2014. (Epub 2014 Jul 21)
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Mets, E, Van der Meulen, J, Van Peer, G, Boice, M, Mestdagh, P, Van de Walle, I, Lammens, T, Goossens, S, De Moerloose, B, Benoit, Y, Van Roy, N, Clappier, E, Poppe, B, Vandesompele, J, Wendel, HG, Taghon, T, Rondou, P, Soulier, J, Van Vlierberghe, P, Speleman, F. MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia Leukemia 29, 798-806, 2014. (Epub 2014 Sep 18)
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Mets, E, Van Peer, G, Van der Meulen, J, Boice, M, Taghon, T, Goossens, S, Mestdagh, P, Benoit, Y, De Moerloose, B, Van Roy, N, Poppe, B, Vandesompele, J, Wendel, HG, Van Vlierberghe, P, Speleman, F, Rondou, P. MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia Haematologica 99, 1326-1333, 2014. (Epub 2014 Jun 3)
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Meuris, L, Santens, F, Elson, G, Festjens, N, Boone, M, Dos Santos, A, Devos, S, Rousseau, F, Plets, E, Houthuys, E, Malinge, P, Magistrelli, G, Cons, L, Chatel, L, Devreese, B, Callewaert, N. GlycoDelete engineering of mammalian cells simplifies N-glycosylation of recombinant proteins Nat Biotechnol 32, 485-489, 2014. (Epub 2014 Apr 20)
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Monteiro, F, Bernal, V, Saelens, X, Lozano, AB, Bernal, C, Sevilla, A, Carrondo, MJ, Alves, PM. Metabolic profiling of insect cell lines: Unveiling cell line determinants behind system's productivity Biotechnol Bioeng 111, 816-828, 2014. (Epub 2013 Oct 28)
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Morreel, K, Saeys, Y, Dima, O, Lu, F, Van de Peer, Y, Vanholme, R, Ralph, J, Vanholme, B, Boerjan, W. Systematic structural characterization of metabolites in Arabidopsis via candidate substrate-product pair networks Plant Cell 26, 929-945, 2014. (Epub 2014 Mar 31)
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Mysara, M, Saeys, Y, Leys, N, Raes, J, Monsieurs, P. CATCh: an ensemble classifier for chimera detection in 16S rRNA sequencing studies Appl Environ Microb 81, 1573-1584, 2014. (Epub 2014 Dec 19)
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Nair, N, Rincon, MY, Evens, H, Sarcar, S, Dastidar, S, Samara-Kuko, E, Ghandeharian, O, Viecelli, HM, Thony, B, De Bleser, P, Vandendriessche, T, Chuah, MK. Computationally designed liver-specific transcriptional cis-regulatory modules and hyper-functional factor IX improve liver-targeted gene therapy for hemophilia B Blood 123, 3195-3199, 2014. (Epub 2014 Mar 17)
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Naramoto, S, Otegui, MS, Kutsuna, N, de Rycke, R, Dainobu, T, Karampelias, M, Fujimoto, M, Feraru, E, Miki, D, Fukuda, H, Nakano, A, Friml, J. Insights into the Localization and Function of the Membrane Trafficking Regulator GNOM ARF-GEF at the Golgi Apparatus in Arabidopsis Plant Cell 26, 3062-3076, 2014. (Epub 2014 Jul)
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Newton, K, Hildebrand, JM, Shen, Z, Rodriguez, D, Alvarez-Diaz, S, Petersen, S, Shah, S, Dugger, DL, Huang, C, Auwerx, J, Vandenabeele, P, Green, DR, Ashkenazi, A, Dixit, VM, Kaiser, WJ, Strasser, A, Degterev, A, Silke, J. Is SIRT2 required for necroptosis? Nature 506, E4-6, 2014. (Epub 2014 Feb 27)
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Niculaes, C, Morreel, K, Kim, H, Lu, F, McKee, LS, Ivens, B, Haustraete, J, Vanholme, B, De Rycke, R, Hertzberg, M, Fromm, J, Bulone, V, Polle, A, Ralph, J, Boerjan, W. Phenylcoumaran benzylic ether reductase prevents accumulation of compounds formed under oxidative conditions in poplar xylem Plant Cell 26, 3775-3791, 2014. (Epub 2014 Sep 19)
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Novakova, P, Hirsch, S, Feraru, E, Tejos, R, van Wijk, R, Viaene, T, Heilmann, M, Lerche, J, De Rycke, R, Feraru, MI, Grones, P, Van Montagu, M, Heilmann, I, Munnik, T, Friml, J. SAC phosphoinositide phosphatases at the tonoplast mediate vacuolar function in Arabidopsis Proceedings of the National Academy of Sciences of the United States of America 111, 2818-2823, 2014. (Epub 2014 Feb 18)
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Osorio, F, Tavernier, SJ, Hoffmann, E, Saeys, Y, Martens, L, Vetters, J, Delrue, I, De Rycke, R, Parthoens, E, Pouliot, P, Iwawaki, T, Janssens, S, Lambrecht, BN. The unfolded-protein-response sensor IRE-1alpha regulates the function of CD8alpha+ dendritic cells Nat Immunol 15, 248-257, 2014. (Epub 2014 Jan 19)
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Peirs, S, Matthijssens, F, Goossens, S, Van de Walle, I, Ruggero, K, de Bock, CE, Degryse, S, Cante-Barrett, K, Briot, D, Clappier, E, Lammens, T, De Moerloose, B, Benoit, Y, Poppe, B, Meijerink, J, Cools, J, Soulier, J, Rabbitts, TH, Taghon, T, Speleman, F, Van Vlierberghe, P. ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia Blood 124, 3738-3747, 2014. (Epub 2014 Oct 9)
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Pieters, T, van Roy, F. Role of cell-cell adhesion complexes in embryonic stem cell biology J Cell Sci 127, 2603-2613, 2014. (Epub 2014 Jun 15)
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Piron, R, De Koker, S, De Paepe, A, Goossens, J, Grooten, J, Nauwynck, H, Depicker, A. Boosting in planta production of antigens derived from the Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) and subsequent evaluation of their immunogenicity PLoS One 9, e91386, 2014. (Epub 2014 Mar 10)
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Pouwels, SD, Heijink, IH, Ten Hacken, NH, Vandenabeele, P, Krysko, DV, Nawijn, MC, van Oosterhout, AJ. DAMPs activating innate and adaptive immune responses in COPD Mucosal Immunol 7, 215-226, 2014. (Epub 2013 Oct 23)
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Puimege, L, Libert, C, Van Hauwermeiren, F. Regulation and dysregulation of tumor necrosis factor receptor-1 Cytokine Growth Factor Rev 25, 285-300, 2014. (Epub 2014 Mar 24)
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Pyfferoen, L, Mestdagh, P, Vergote, K, De Cabooter, N, Vandesompele, J, Lambrecht, BN, Vermaelen, KY. Lung tumours reprogram pulmonary dendritic cell immunogenicity at the microRNA level Int J Cancer 135, 2868-2877, 2014. (Epub 2014 May 2)
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Quimbaya, M, Raspe, E, Denecker, G, De Craene, B, Roelandt, R, Declercq, W, Sagaert, X, De Veylder, L, Berx, G. Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability Neoplasia 16, 694-709, 2014. (Epub 2014 Sep)
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Ramboer, E, De Craene, B, De Kock, J, Vanhaecke, T, Berx, G, Rogiers, V, Vinken, M. Strategies for immortalization of primary hepatocytes J Hepatol 61, 925-943, 2014. (Epub 2014 Jun 6)
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Ramentol, E, Vluymans, S, Verbiest, N, Caballero, Y, Bello Perez, R, Cornelis, C, Herrera, F. IFROWANN: Imbalanced Fuzzy-Rough Ordered Weighted Average Nearest Neighbor Classification Fuzzy Systems, IEEE Transactions on 23, 1622-1637, 2014. (Epub 2014 Nov 20)
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Rankin, SA, Thi Tran, H, Wlizla, M, Mancini, P, Shifley, ET, Bloor, SD, Han, L, Vleminckx, K, Wert, SE, Zorn, AM. A molecular atlas of Xenopus respiratory system development Dev Dyn 244, 69-85, 2014. (Epub 2014 Aug 26)
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Remijsen, Q, Goossens, V, Grootjans, S, Van den Haute, C, Vanlangenakker, N, Dondelinger, Y, Roelandt, R, Bruggeman, I, Goncalves, A, Bertrand, MJ, Baekelandt, V, Takahashi, N, Vanden Berghe, T, Vandenabeele, P. Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis Cell Death Dis 5, e1004, 2014. (Epub 2014 Jan 16)
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Rincon, MY, Sarcar, S, Danso-Abeam, D, Keyaerts, M, Matrai, J, Samara-Kuko, E, Acosta-Sanchez, A, Athanasopoulos, T, Dickson, G, Lahoutte, T, De Bleser, P, VandenDriessche, T, Chuah, MK. Genome-wide computational analysis reveals cardiomyocyte-specific transcriptional cis-regulatory motifs that enable efficient cardiac gene therapy Mol Ther 23, 43-52, 2014. (Epub 2014 Sep 8)
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Robajac, D, Masnikosa, R, Vanhooren, V, Libert, C, Mikovic, Z, Nedic, O. The N-glycan profile of placental membrane glycoproteins alters during gestation and ageing Mech Ageing Dev 138, 1-9, 2014. (Epub 2014 Feb 10)
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Rossey, I, Sedeyn, K, De Baets, S, Schepens, B, Saelens, X. CD8+ T cell immunity against human respiratory syncytial virus Vaccine 32, 6130-6137, 2014. (Epub Q2: 35/122)
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Ruyssinck, J, Huynh-Thu, VA, Geurts, P, Dhaene, T, Demeester, P, Saeys, Y. NIMEFI: Gene regulatory network inference using multiple ensemble feature importance algorithms PLoS One 9, e92709, 2014. (Epub 2014 Mar 25)
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Schepens, B, Sedeyn, K, Vande Ginste, L, De Baets, S, Schotsaert, M, Roose, K, Houspie, L, Van Ranst, M, Gilbert, B, van Rooijen, N, Fiers, W, Piedra, P, Saelens, X. Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein EMBO Mol Med 6, 1436-1454, 2014. (Epub 2014 Oct 8)
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Scott, CL, Bain, CC, Wright, PB, Sichien, D, Kotarsky, K, Persson, EK, Luda, K, Guilliams, M, Lambrecht, BN, Agace, WW, Milling, SW, Mowat, AM. CCR2CD103 intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells Mucosal Immunol 8, 327-339, 2014. (Epub 2014 Aug 20)
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Scott, CL, Henri, S, Guilliams, M. Mononuclear phagocytes of the intestine, the skin, and the lung Immunol Rev 262, 9-24, 2014. (Epub 2014 Oct 15)
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Scott, CL, Murray, TF, Beckham, KS, Douce, G, Mowat, AM. Signal Regulatory Protein alpha (SIRPalpha) regulates the homeostasis of CD103 CD11b DCs in the intestinal lamina propria Eur J Immunol 44, 3658-68, 2014. (Epub 2014 Sep 19)
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Silence, K, Dreier, T, Moshir, M, Ulrichts, P, Gabriels, SME, Saunders, M, Wajant, H, Brouckaert, P, Huyghe, L, Van Hauwermeiren, T, Thibault, A, De Haard, HJ. ARGX-110, a highly potent antibody targeting CD70, eliminates tumors via both enhanced ADCC and immune checkpoint blockade mAbs 6, 523-532, 2014. (Epub 2013 Dec 6)
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Sipieter, F, Ladik, M, Vandenabeele, P, Riquet, F. Shining light on cell death processes - a novel biosensor for necroptosis, a newly described cell death program Biotechnol J 9, 224-240, 2014. (Epub 2014 Jan 3)
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Steeland, S, Puimege, L, Vandenbroucke, RE, Van Hauwermeiren, F, Haustraete, J, Devoogdt, N, Hulpiau, P, Leroux-Roels, G, Laukens, D, Meuleman, P, De Vos, M, Libert, C. Generation and characterization of small single domain antibodies inhibiting human TNF receptor 1 J Biol Chem 290, 4022-4037, 2014. (Epub 2014 Dec 23)
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Svandova, E, Lesot, H, Vanden Berghe, T, Tucker, AS, Sharpe, PT, Vandenabeele, P, Matalova, E. Non-apoptotic functions of caspase-7 during osteogenesis Cell Death Dis 5, e1366, 2014. (Epub 2014 Aug 14)
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Takahashi, N, Vereecke, L, Bertrand, MJ, Duprez, L, Berger, SB, Divert, T, Goncalves, A, Sze, M, Gilbert, B, Kourula, S, Goossens, V, Lefebvre, S, Gunther, C, Becker, C, Bertin, J, Gough, PJ, Declercq, W, van Loo, G, Vandenabeele, P. RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis Nature 513, 95-99, 2014. (Epub 2014 Sep 4)
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Tatari, MN, De Craene, B, Soen, B, Taminau, J, Vermassen, P, Goossens, S, Haigh, K, Cazzola, S, Lambert, J, Huylebroeck, D, Haigh, JJ, Berx, G. ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins Cell Mol Life Sci 71, 3599-3609, 2014. (Epub 2014 Feb 27)
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Tegtmeyer, LC, Rust, S, van Scherpenzeel, M, Ng, BG, Losfeld, ME, Timal, S, Raymond, K, He, P, Ichikawa, M, Veltman, J, Huijben, K, Shin, YS, Sharma, V, Adamowicz, M, Lammens, M, Reunert, J, Witten, A, Schrapers, E, Matthijs, G, Jaeken, J, Rymen, D, Stojkovic, T, Laforet, P, Petit, F, Aumaitre, O, Czarnowska, E, Piraud, M, Podskarbi, T, Stanley, CA, Matalon, R, Burda, P, Seyyedi, S, Debus, V, Socha, P, Sykut-Cegielska, J, van Spronsen, F, de Meirleir, L, Vajro, P, DeClue, T, Ficicioglu, C, Wada, Y, Wevers, RA, Vanderschaeghe, D, Callewaert, N, Fingerhut, R, van Schaftingen, E, Freeze, HH, Morava, E, Lefeber, DJ, Marquardt, T. Multiple phenotypes in phosphoglucomutase 1 deficiency N Engl J Med 370, 533-542, 2014. (Epub 2014 Feb 6)
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Titeca, K, Aerts, L, Krols, M, Vandersarren, L, Akay, O, Yilmaz, S, Hristozova, N, Janiak, M. From challenges to perspectives: Reflections of young scientists on the current state of academic research EMBO Rep 15, 1010-1014, 2014. (Epub 2014 Sep 12)
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Tran, HT, Vleminckx, K. Design and use of transgenic reporter strains for detecting activity of signaling pathways in Xenopus Methods 66, 422-432, 2014. (Epub 2013 Jun 28)
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Vandamme, N, Berx, G. Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity Front Oncol 4, 1-6, 2014. (Epub 2014 Dec 9)
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van de Laar, L, Lambrecht, BN. How to generate large numbers of CD103+ dendritic cells Blood 124, 3036-3038, 2014. (Epub 2014 Nov 13)
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Vanden Berghe, T, Demon, D, Bogaert, P, Vandendriessche, B, Goethals, A, Depuydt, B, Vuylsteke, M, Roelandt, R, Van Wonterghem, E, Vandenbroecke, J, Choi, SM, Meyer, E, Krautwald, S, Declercq, W, Takahashi, N, Cauwels, A, Vandenabeele, P. Simultaneous targeting of Interleukin-1 and -18 is required for protection against inflammatory and septic shock Am J Respir Crit Care Med 189, 282-291, 2014. (Epub 2014 Jan 23)
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Vanden Berghe, T, Linkermann, A, Jouan-Lanhouet, S, Walczak, H, Vandenabeele, P. Regulated necrosis: the expanding network of non-apoptotic cell death pathways Nat Rev Mol Cell Biol 15, 135-147, 2014. (Epub 2014 Jan 23)
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Vandenbroucke, RE, Libert, C. Is there new hope for therapeutic matrix metalloproteinase inhibition? Nat Rev Drug Discov , 904-927, 2014. (Epub 2014 Nov 7)
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Vandenbroucke, RE, Vanlaere, I, Van Hauwermeiren, F, Van Wonterghem, E, Wilson, C, Libert, C. Pro-inflammatory effects of matrix metalloproteinase 7 in acute inflammation Mucosal Immunol 7, 579-588, 2014. (Epub 2013 Oct 16)
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Vandendriessche, B, Goethals, A, Simats, A, Van Hamme, E, Brouckaert, P, Cauwels, A. MAPK-activated protein kinase 2-deficiency causes hyperacute tumor necrosis factor-induced inflammatory shock BMC Physiol 14, 5, 2014. (Epub 2014 Sep 4)
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