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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Van Coillie, S, Van San, E, Goetschalckx, I, Wiernicki, B, Mukhopadhyay, B, Tonnus, W, Choi, SM, Roelandt, R, Dumitrascu, C, Lamberts, L, Dams, G, Weyts, W, Huysentruyt, J, Hassannia, B, Ingold, I, Lele, S, Meyer, E, Berg, M, Seurinck, R, et al.. Targeting ferroptosis protects against experimental (multi)organ dysfunction and death Nat Commun 13, 1046, 2022. (Epub 2022 Feb 24) 
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Vanderhaeghen, T, Timmermans, S, Watts, D, Paakinaho, V, Eggermont, M, Vandewalle, J, Wallaeys, C, Van Wyngene, L, Van Looveren, K, Nuyttens, L, Dewaele, S, Vanden Berghe, J, Lemeire, K, De Backer, J, Dirkx, L, Vanden Berghe, W, Caljon, G, Ghesquiere, B, De Bosscher, K, et al.. Reprogramming of glucocorticoid receptor function by hypoxia EMBO Rep 23, e53083, 2022. (Epub 2021 Oct 26)
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Vandewalle, J, Libert, C. Sepsis: a failing starvation response Trends Endocrinol Metab 33, 292-304, 2022. (Epub 2022 Feb 15)
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Van Hauwermeiren, F, Van Opdenbosch, N, Van Gorp, H, de Vasconcelos, N, van Loo, G, Vandenabeele, P, Kanneganti, TD, Lamkanfi, M. Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax Proc Natl Acad Sci U S A 119, e2116415119, 2022. (Epub 2022 Jan 11)
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Van Hoovels, L, Studholme, L, Vander Cruyssen, B, Sieghart, D, Bonroy, C, Nagy, E, Pullerits, R, Cucnik, S, Dahle, C, Heijnen, I, Bernasconi, L, Benkhadra, F, Bogaert, L, Van Den Bremt, S, Van Liedekerke, A, Vanheule, G, Robbrecht, J, Wirth, C, Muller, R, et al.. Standardisation of ACPA tests: evaluation of a new candidate reference preparation Ann Rheum Dis , in press, 2022. (Epub 2022 Jun 13)
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Van Hoovels, L, Vander Cruyssen, B, Sieghart, D, Bonroy, C, Nagy, E, Pullerits, R, Cucnik, S, Dahle, C, Heijnen, I, Bernasconi, L, Benkhadra, F, Bogaert, L, Van Den Bremt, S, Van Liedekerke, A, Vanheule, G, Robbrecht, J, Studholme, L, Wirth, C, Muller, R, et al.. IgA rheumatoid factor in rheumatoid arthritis Clin Chem Lab Med in press, , 2022. (Epub 2022 Jul 6)
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Van Hoovels, L, Vander Cruyssen, B, Sieghart, D, Bonroy, C, Nagy, E, Pullerits, R, Cucnik, S, Dahle, C, Heijnen, I, Bernasconi, L, Benkhadra, F, Bogaert, L, Van Den Bremt, S, Van Liedekerke, A, Vanheule, G, Robbrecht, J, Studholme, L, Wirth, C, Muller, R, et al.. Multicentre study to improve clinical interpretation of rheumatoid factor and anti-citrullinated protein/peptide antibodies test results RMD Open 8, e002099, 2022. (Epub 2022 Mar)
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Van Hove, L, Hoste, E. Activation of Fibroblasts in Skin Cancer J Invest Dermatol 142, 1026-1031, 2022. (Epub 2021 Sep 30)
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Van Moortel, L, Thommis, J, Maertens, B, Staes, A, Clarisse, D, De Sutter, D, Libert, C, Meijer, OC, Eyckerman, S, Gevaert, K, De Bosscher, K. Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets Biomed Pharmacother 152, 113218, 2022. (Epub 2022 Jun 13)
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Van Nevel, S, Declercq, J, Holtappels, G, Lambrecht, BN, Bachert, C. Granulocyte-colony stimulating factor: Missing link for stratification of type 2-high and type 2-low chronic rhinosinusitis patients J Allergy Clin Immunol 149, 1655-1665, 2022. (Epub 2022 Mar 9)
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Varasteh, Z, Braeuer, M, Mohanta, S, Steinsiek, AL, Habenicht, A, Omidvari, N, Topping, GJ, Rischpler, C, Weber, WA, Sager, HB, Raes, G, Hernot, S, Schwaiger, M. In vivo Visualization of M2 Macrophages in the Myocardium After Myocardial Infarction (MI) Using (68) Ga-NOTA-Anti-MMR Nb: Targeting Mannose Receptor (MR, CD206) on M2 Macrophages Front Cardiovasc Med 9, 889963, 2022. (Epub 2022 Apr 25)
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Verdonck, S, Nemegeer, J, Vandenabeele, P, Maelfait, J. Viral manipulation of host cell necroptosis and pyroptosis Trends Microbiol 30, 593-605, 2022. (Epub 2021 Dec 18)
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Verheye, E, Bravo Melgar, J, Deschoemaeker, S, Raes, G, Maes, A, De Bruyne, E, Menu, E, Vanderkerken, K, Laoui, D, De Veirman, K. Dendritic Cell-Based Immunotherapy in Multiple Myeloma: Challenges, Opportunities, and Future Directions Int J Mol Sci 23, 904, 2022. (Epub 2022 Jan 14)
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Whyte, CE, Singh, K, Burton, OT, Aloulou, M, Kouser, L, Veiga, RV, Dashwood, A, Okkenhaug, H, Benadda, S, Moudra, A, Bricard, O, Lienart, S, Bielefeld, P, Roca, CP, Naranjo-Galindo, FJ, Lombard-Vadnais, F, Junius, S, Bending, D, Ono, MM, et al.. Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits J Exp Med 219, e20212391, 2022. (Epub 2022 Jul 4)
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Wiernicki, B, Maschalidi, S, Pinney, J, Adjemian, S, Vanden Berghe, T, Ravichandran, KS, Vandenabeele, P. Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity Nat Commun 13, 3676, 2022. (Epub 2022 Jun 27)
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Wynendaele, E, Debunne, N, Janssens, Y, De Spiegeleer, A, Verbeke, F, Tack, L, Van Welden, S, Goossens, E, Knappe, D, Hoffmann, R, Van De Wiele, C, Laukens, D, Van Eenoo, P, Vereecke, L, Van Immerseel, F, De Wever, O, De Spiegeleer, B. The quorum sensing peptide EntF* promotes colorectal cancer metastasis in mice: a new factor in the host-microbiome interaction BMC Biol 20, 151, 2022. (Epub 2022 Jun 27)
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Xiao, P, Takiishi, T, Violato, NM, Licata, G, Dotta, F, Sebastiani, G, Marselli, L, Singh, SP, Sze, M, Van Loo, G, Dejardin, E, Gurzov, EN, Cardozo, AK. NF-kappaB-inducing kinase (NIK) is activated in pancreatic beta-cells but does not contribute to the development of diabetes Cell Death Dis 13, 476, 2022. (Epub 2022 May 19)
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Xie, J, Li, Q, Haesebrouck, F, Van Hoecke, L, Vandenbroucke, RE. The tremendous biomedical potential of bacterial extracellular vesicles Trends Biotechnol , in press, 2022. (Epub 2022 May 14)
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Xie, J, Van Hoecke, L, Vandenbroucke, RE. The Impact of Systemic Inflammation on Alzheimer's Disease Pathology Front Immunol 12, 796867, 2022. (Epub 2022 Jan 6)
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Yshii, L, Pasciuto, E, Bielefeld, P, Mascali, L, Lemaitre, P, Marino, M, Dooley, J, Kouser, L, Verschoren, S, Lagou, V, Kemps, H, Gervois, P, de Boer, A, Burton, OT, Wahis, J, Verhaert, J, Tareen, SHK, Roca, CP, Singh, K, et al.. Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation Nat Immunol 23, 878-891, 2022. (Epub 2022 May 26)
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Aaes, TL, Vandenabeele, P. The intrinsic immunogenic properties of cancer cell lines, immunogenic cell death, and how these influence host antitumor immune responses Cell Death Differ 28, 843-860, 2021. (Epub 2020 Nov 19)
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Ackaert, C, Smiejkowska, N, Xavier, C, Sterckx, YGJ, Denies, S, Stijlemans, B, Elkrim, Y, Devoogdt, N, Caveliers, V, Lahoutte, T, Muyldermans, S, Breckpot, K, Keyaerts, M. Immunogenicity Risk Profile of Nanobodies Front Immunol 12, 632687, 2021. (Epub 2021 Mar 9)
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Ackermann, M, Anders, HJ, Bilyy, R, Bowlin, GL, Daniel, C, De Lorenzo, R, Egeblad, M, Henneck, T, Hidalgo, A, Hoffmann, M, Hohberger, B, Kanthi, Y, Kaplan, MJ, Knight, JS, Knopf, J, Kolaczkowska, E, Kubes, P, Leppkes, M, Mahajan, A, et al.. Patients with COVID-19: in the dark-NETs of neutrophils Cell Death Differ 28, 3125-3139, 2021. (Epub 2021 May 24)
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Adami, V, Homer, N, Utz, N, Lippens, S, Rappoport, JZ, Fernandez-Rodriguez, J. An international survey of Training Needs and Career Paths of Core Facility Staff J Biomol Tech 32, 1-9, 2021. (Epub 2020 Nov 20)
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Aegerter, H, Smole, U, Heyndrickx, I, Verstraete, K, Savvides, SN, Hammad, H, Lambrecht, BN. Charcot-Leyden crystals and other protein crystals driving type 2 immunity and allergy Curr Opin Immunol 72, 104-110, 2021. (Epub 2021 Apr 16)
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Afonina, IS, Van Nuffel, E, Beyaert, R. Immune responses and therapeutic options in psoriasis Cell Mol Life Sci 78, 2709–2727, 2021. (Epub 2021 Jan 2)
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Aguilera-Lizarraga, J, Florens, MV, Viola, MF, Jain, P, Decraecker, L, Appeltans, I, Cuende-Estevez, M, Fabre, N, Van Beek, K, Perna, E, Balemans, D, Stakenborg, N, Theofanous, S, Bosmans, G, Mondelaers, SU, Matteoli, G, Ibiza Martinez, S, Lopez-Lopez, C, Jaramillo-Polanco, J, et al.. Local immune response to food antigens drives meal-induced abdominal pain Nature 590, 151-156, 2021. (Epub 2021 Jan 13)
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Alexander, SP, Fabbro, D, Kelly, E, Mathie, A, Peters, JA, Veale, EL, Armstrong, JF, Faccenda, E, Harding, SD, Pawson, AJ, Southan, C, Davies, JA, Beuve, A, Brouckaert, P, Bryant, C, Burnett, JC, Farndale, RW, Friebe, A, Garthwaite, J, et al.. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors Br J Pharmacol 178, S264-S312, 2021. (Epub 2021 Sep 17)
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Almeida, L, Dhillon-LaBrooy, A, Castro, CN, Adossa, N, Carriche, GM, Guderian, M, Lippens, S, Dennerlein, S, Hesse, C, Lambrecht, BN, Berod, L, Schauser, L, Blazar, BR, Kalesse, M, Muller, R, Moita, LF, Sparwasser, T. Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis Immunity 54, 68-83, 2021. (Epub 2020 Nov 24)
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Anderson, CJ, Medina, CB, Barron, BJ, Karvelyte, L, Aaes, TL, Lambertz, I, Perry, JSA, Mehrotra, P, Goncalves, A, Lemeire, K, Blancke, G, Andries, V, Ghazavi, F, Martens, A, van Loo, G, Vereecke, L, Vandenabeele, P, Ravichandran, KS. Microbes exploit death-induced nutrient release by gut epithelial cells Nature 596, 262-267, 2021. (Epub 2021 Aug 4)
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Andries, L, Masin, L, Navarro, MS, Zaunz, S, Claes, M, Bergmans, S, Brouwers, V, Lefevere, E, Verfaillie, C, Movahedi, K, De Groef, L, Moons, L. MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System Cells 10, 1672, 2021. (Epub 2021 Jul 2)
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Arandjelovic, S, Perry, JSA, Zhou, M, Ceroi, A, Smirnov, I, Walk, SF, Shankman, LS, Cambre, I, Onengut-Gumuscu, S, Elewaut, D, Conrads, TP, Ravichandran, KS. ELMO1 signaling is a promoter of osteoclast function and bone loss Nat Commun 12, 4974, 2021. (Epub 2021 Aug 17)
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Awad, RM, Lecocq, Q, Zeven, K, Ertveldt, T, De Beck, L, Ceuppens, H, Broos, K, De Vlaeminck, Y, Goyvaerts, C, Verdonck, M, Raes, G, Van Parys, A, Cauwels, A, Keyaerts, M, Devoogdt, N, Breckpot, K. Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade Mol Ther Methods Clin Dev 22, 172-182, 2021. (Epub 2021 Sep 10)
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Backers, L, Parton, B, De Bruyne, M, Tavernier, SJ, Van Den Bogaert, K, Lambrecht, BN, Haerynck, F, Claes, KBM. Missing heritability in Bloom syndrome: First report of a deep intronic variant leading to pseudo-exon activation in the BLM gene Clin Genet 99, 292-297, 2021. (Epub 2020 Oct 9)
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Baldan, FJ, Peralta, D, Saeys, Y, Benitez, JM. SCMFTS: Scalable and Distributed Complexity Measures and Features for Univariate and Multivariate Time Series in Big Data Environments International Journal of Computational Intelligence Systems 14, 186, 2021. (Epub 2021 Nov 2)
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Baptista, AP, Gerner, MY. Lymphoid stromal cells proGrem dendritic cell homeostasis Nat Immunol 22, 541-543, 2021. (Epub 2021 Apr 26)
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Baraliakos, X, Van den Bosch, F, Machado, PM, Gensler, LS, Marzo-Ortega, H, Sherif, B, Quebe-Fehling, E, Porter, B, Gaillez, C, Deodhar, A. Achievement of Remission Endpoints with Secukinumab Over 3 Years in Active Ankylosing Spondylitis: Pooled Analysis of Two Phase 3 Studies Rheumatol Ther 8, 273-288, 2021. (Epub 2020 Dec 22)
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Barca, C, Foray, C, Hermann, S, Herrlinger, U, Remory, I, Laoui, D, Schafers, M, Grauer, OM, Zinnhardt, B, Jacobs, AH. The Colony Stimulating Factor-1 Receptor (CSF-1R)-Mediated Regulation of Microglia/Macrophages as a Target for Neurological Disorders (Glioma, Stroke) Front Immunol 12, 787307, 2021. (Epub 2021 Dec 7)
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Baudhuin, H, Cousaert, J, Vanwolleghem, P, Raes, G, Caveliers, V, Keyaerts, M, Lahoutte, T, Xavier, C. (68)Ga-Labeling: Laying the Foundation for an Anti-Radiolytic Formulation for NOTA-sdAb PET Tracers Pharmaceuticals (Basel) 14, 448, 2021. (Epub 2021 May 10)
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Baudhuin, H, Puttemans, J, Hanssens, H, Vanwolleghem, P, Hernot, S, Raes, G, Xavier, C, Lahoutte, T, Debie, P. Decorating sdAbs with Chelators: Effect of Conjugation on Biodistribution and Functionality Pharmaceuticals (Basel) 14, 407, 2021. (Epub 2021 Apr 25)
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Baudhuin, H, Van Bockstal, PJ, De Beer, T, Vaneycken, I, Bridoux, J, Raes, G, Caveliers, V, Keyaerts, M, Devoogdt, N, Lahoutte, T, Xavier, C. Lyophilization of NOTA-sdAbs: first step towards a cold diagnostic kit for (68)Ga-labeling Eur J Pharm Biopharm 166, 194-204, 2021. (Epub 2021 Jun 26)
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Behrens, F, Leage, SL, Sapin, C, Baou, CE, De La Torre, I, Meszaros, G, Schett, G, Combe, B, van den Bosch, F, Gossec, L. Measuring treatment effect on psoriatic arthritis-related domains: insights from the SPIRIT-H2H study at weeks 24 and 52 Clin Rheumatol 40, 4943-4954, 2021. (Epub 2021 Sep 13)
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Berlamont, H, Bruggeman, A, Bauwens, E, Vandendriessche, C, Clarebout, E, Xie, J, De Bruyckere, S, Van Imschoot, G, Van Wonterghem, E, Ducatelle, R, Santens, P, Smet, A, Haesebrouck, F, Vandenbroucke, RE. Gastric Helicobacter suis Infection Partially Protects against Neurotoxicity in A 6-OHDA Parkinson's Disease Mouse Model Int J Mol Sci 22, 11328, 2021. (Epub 2021 Oct 20)
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Bolli, E, Scherger, M, Arnouk, SM, Pombo Antunes, AR, Strassburger, D, Urschbach, M, Stickdorn, J, De Vlaminck, K, Movahedi, K, Rader, HJ, Hernot, S, Besenius, P, Van Ginderachter, JA, Nuhn, L. Targeted Repolarization of Tumor-Associated Macrophages via Imidazoquinoline-Linked Nanobodies Adv Sci (Weinh) 8, 2004574, 2021. (Epub 2021 Mar 8)
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Borras-Tuduri, R, Alcaide, A, Aspeslag, S, Usero, L, Serra, C, Roura-Mir, C, Elewaut, D, Llebaria, A. New paradigm in NKT cell antigens: MCS-0208 (2-(Hydroxymethyl)phenylthio-phytoceramide) an aryl-phytoceramide compound with a single hydroxyl group stimulates NKT cells ChemMedChem 16, 2491-2496, 2021. (Epub 2021 Apr 6)
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Bosteels, C, Fierens, K, De Prijck, S, Van Moorleghem, J, Vanheerswynghels, M, De Wolf, C, Chalon, A, Collignon, C, Hammad, H, Didierlaurent, AM, Lambrecht, BN. CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Immunity by the Human Vaccine Adjuvant System AS01 Front Immunol 11, 606805, 2021. (Epub 2021 Jan 14)
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Braun, J, Blanco, R, Marzo-Ortega, H, Gensler, LS, van den Bosch, F, Hall, S, Kameda, H, Poddubnyy, D, van de Sande, M, Wiksten, AS, Porter, BO, Shete, A, Richards, HB, Haemmerle, S, Deodhar, A. Secukinumab in non-radiographic axial spondyloarthritis: subgroup analysis based on key baseline characteristics from a randomized phase III study, PREVENT Arthritis Res Ther 23, 231, 2021. (Epub 2021 Sep 4)
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Brightling, C, Kulkarni, S, Lambrecht, BN, Sandham, D, Weiss, M, Altman, P. The pharmacology of the prostaglandin D2 receptor 2 (DP2) receptor antagonist, fevipiprant Pulm Pharmacol Ther 68, 102030, 2021. (Epub 2021 Apr 4)
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Burgelman, M, Vandendriessche, C, Vandenbroucke, RE. Extracellular Vesicles: A Double-Edged Sword in Sepsis Pharmaceuticals (Basel) 14, 829, 2021. (Epub 2021 Aug 23)
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Cable, J, Elowitz, MB, Domingos, AI, Habib, N, Itzkovitz, S, Hamidzada, H, Balzer, MS, Yanai, I, Liberali, P, Whited, J, Streets, A, Cai, L, Stergachis, AB, Hong, CKY, Keren, L, Guilliams, M, Alon, U, Shalek, AK, Hamel, R, et al.. Single cell biology-a Keystone Symposia report Ann N Y Acad Sci 1506, 74-97, 2021. (Epub 2021 Oct 3)
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