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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Dondelinger, Y, Declercq, W, Montessuit, S, Roelandt, R, Goncalves, A, Bruggeman, I, Hulpiau, P, Weber, K, Sehon, CA, Marquis, RW, Bertin, J, Gough, PJ, Savvides, S, Martinou, JC, Bertrand, MJ, Vandenabeele, P. MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates Cell Rep 7, 971–981, 2014. (Epub 2014 May 7) 
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Dupont, LL, Glynos, C, Bracke, KR, Brouckaert, P, Brusselle, GG. Role of the nitric oxide - soluble guanylyl cyclase pathway in obstructive airway diseases Pulm Pharmacol Ther 29, 1-6, 2014. (Epub 2014 Jul 17)
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Estornes, Y, Aguileta, MA, Dubuisson, C, De Keyser, J, Goossens, V, Kersse, K, Samali, A, Vandenabeele, P, Bertrand, MJ. RIPK1 promotes death receptor-independent caspase-8-mediated apoptosis under unresolved ER stress conditions Cell Death Dis 5, e1555, 2014. (Epub 2014 Dec 4)
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Estornes, Y, Bertrand, MJ. IAPs, regulators of innate immunity and inflammation Semin Cell Dev Biol 39, 106-114, 2014. (Epub 2014 Apr 6)
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Farhang Ghahremani, M, Radaelli, E, Haigh, K, Bartunkova, S, Haenebalcke, L, Marine, JC, Goossens, S, Haigh, JJ. Loss of autocrine endothelial-derived VEGF significantly reduces hemangiosarcoma development in conditional p53-deficient mice Cell Cycle 13, 1501-1507, 2014. (Epub 2014 Mar 11)
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Fendrych, M, Van Hautegem, T, Van Durme, M, Olvera-Carrillo, Y, Huysmans, M, Karimi, M, Lippens, S, Guerin, CJ, Krebs, M, Schumacher, K, Nowack, MK. Programmed cell death controlled by ANAC033/SOMBRERO determines root cap organ size in Arabidopsis Curr Biol 24, 931-940, 2014. (Epub 2014 Apr 9)
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Folmsbee, SS, Morales-Nebreda, L, Van Hengel, J, Tyberghein, K, Van Roy, F, Budinger, GS, Bryce, PJ, Gottardi, CJ. The cardiac protein alpha-T-Catenin contributes to chemical-induced asthma Am J Physiol Lung Cell Mol Physiol 308, L253-L258, 2014. (Epub 2014 Dec 5)
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Galluzzi, L, Bravo-San Pedro, JM, Vitale, I, Aaronson, SA, Abrams, JM, Adam, D, Alnemri, ES, Altucci, L, Andrews, D, Annicchiarico-Petruzzelli, M, Baehrecke, EH, Bazan, NG, Bertrand, MJ, Bianchi, K, Blagosklonny, MV, Blomgren, K, Borner, C, Bredesen, DE, Brenner, C, Campanella, M, Candi, E, Cecconi, F, Chan, FK, Chandel, NS, Cheng, EH, Chipuk, JE, Cidlowski, JA, Ciechanover, A, Dawson, TM, Dawson, VL, De Laurenzi, V, De Maria, R, Debatin, KM, Di Daniele, N, Dixit, VM, Dynlacht, BD, El-Deiry, WS, Fimia, GM, Flavell, RA, Fulda, S, Garrido, C, Gougeon, ML, Green, DR, Gronemeyer, H, Hajnoczky, G, Hardwick, JM, Hengartner, MO, Ichijo, H, Joseph, B, Jost, PJ, Kaufmann, T, Kepp, O, Klionsky, DJ, Knight, RA, Kumar, S, Lemasters, JJ, Levine, B, Linkermann, A, Lipton, SA, Lockshin, RA, Lopez-Otin, C, Lugli, E, Madeo, F, Malorni, W, Marine, JC, Martin, SJ, Martinou, JC, Medema, JP, Meier, P, Melino, S, Mizushima, N, Moll, U, Munoz-Pinedo, C, Nunez, G, Oberst, A, Panaretakis, T, Penninger, JM, Peter, ME, Piacentini, M, Pinton, P, Prehn, JH, Puthalakath, H, Rabinovich, GA, Ravichandran, KS, Rizzuto, R, Rodrigues, CM, Rubinsztein, DC, Rudel, T, Shi, Y, Simon, HU, Stockwell, BR, Szabadkai, G, Tait, SW, Tang, HL, Tavernarakis, N, Tsujimoto, Y, Vanden Berghe, T, Vandenabeele, P, Villunger, A, Wagner, EF, Walczak, H, White, E, Wood, WG, Yuan, J, Zakeri, Z, Zhivotovsky, B, Melino, G, Kroemer, G. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 Cell Death Differ 22, 58-73, 2014. (Epub 2014 Sep 19)
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Garcin, G, Paul, F, Staufenbiel, M, Bordat, Y, Van der Heyden, J, Wilmes, S, Cartron, G, Apparailly, F, De Koker, S, Piehler, J, Tavernier, J, Uzé, G. High efficiency cell-specific targeting of cytokine activity Nat Comm 5, 3016, 2014. (Epub 2014 Jan 8)
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Giordano, M, Roncagalli, R, Bourdely, P, Chasson, L, Buferne, M, Yamasaki, S, Beyaert, R, van Loo, G, Auphan-Anezin, N, Schmitt-Verhulst, AM, Verdeil, G. The tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cells Proc Natl Acad Sci USA 111, 11115-11120, 2014. (Epub 2014 Jul 14)
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Glynos, C, Toumpanakis, D, Loverdos, K, Karavana, V, Zhou, Z, Magkou, C, Dettoraki, M, Perlikos, F, Pavlidou, A, Kotsikoris, V, Topouzis, S, Theocharis, SE, Brouckaert, P, Giannis, A, Papapetropoulos, A, Vassilakopoulos, T. Guanylyl cyclase activation reverses resistive breathing-induced lung injury and inflammation Am J Resp Cell Mol Biol 52, 762-771, 2014. (Epub 2014 Oct 29)
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Goossens, S, Van Vlierberghe, P. Controlling Pre-leukemic Thymocyte Self-Renewal PLoS Genet 10, e1004881, 2014. (Epub 2014 Dec 18)
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Grine, L, Dejager, L, Libert, C, Vandenbroucke, RE. An inflammatory triangle in psoriasis: TNF, type I IFNs and IL-17 Cytok Growth Factor Rev 26, 25-33, 2014. (Epub 2014 Oct 31)
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Guabiraba, R, Besnard, AG, Menezes, GB, Secher, T, Jabir, MS, Amaral, SS, Braun, H, Lima-Junior, RC, Ribeiro, RA, Cunha, FQ, Teixeira, MM, Beyaert, R, Graham, GJ, Liew, FY. IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice Mucosal Immunol 7, 1079-1093, 2014. (Epub 2014 Jan 15)
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Guilliams, M, Bruhns, P, Saeys, Y, Hammad, H, Lambrecht, BN. The function of Fc? receptors in dendritic cells and macrophages Nat Rev Immunol 14, 94-108, 2014. (Epub 2014 Jan 21)
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Guilliams, M, Ginhoux, F, Jakubzick, C, Naik, SH, Onai, N, Schraml, BU, Segura, E, Tussiwand, R, Yona, S. Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny Nat Rev Immunol 14, 571-578, 2014. (Epub 2014 Jul 18)
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Hachez, C, Laloux, T, Reinhardt, H, Cavez, D, Degand, H, Grefen, C, De Rycke, R, Inze, D, Blatt, MR, Russinova, E, Chaumont, F. Arabidopsis SNAREs SYP61 and SYP121 Coordinate the Trafficking of Plasma Membrane Aquaporin PIP2;7 to Modulate the Cell Membrane Water Permeability Plant Cell 26, 3132-3147, 2014. (Epub 2014 Jul)
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Hautefort, A, Girerd, B, Montani, D, Cohen Kaminsky, S, Price, L, Lambrecht, BN, Humbert, M, Perros, F. Th17 polarization in pulmonary arterial hypertension Chest 147, 1610-1620, 2014. (Epub 2014 Nov 27)
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Heger, K, Fierens, K, Vahl, C, Aszodi, A, Peschke, K, Schenten, D, Hammad, H, Beyaert, R, Saur, D, van Loo, G, Roers, A, Lambrecht, BN, Kool, M, Schmidt-Supprian, M. A20-deficient mast cells exacerbate inflammatory responses in vivo PLoS Biol 12, e1001762, 2014. (Epub 2014 Jan 14)
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Hervé, D, Philippi, A, Belbouab, R, Zerah, M, Chabrier, S, Collardeau-Frachon, S, Bergametti, F, Essongue, A, Berrou, E, Krivosic, V, Sainte-Rose, C, Houdart, E, Adam, F, Billiemaz, K, Lebret, M, Roman, S, Passemard, S, Boulday, G, Delaforge, A, Guey, S, Dray, X, Chabriat, H, Brouckaert, P, Bryckaer, M, Tournier-Lasserve, E. Loss of alfa-1 beta-1 soluble guanylate cyclase, the major nitric oxide receptor, leads to moyamoya and achalasia. Am J Hum Genet 94, 385-394, 2014. (Epub 2014 Feb 25)
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Janssens, S, Pulendran, B, Lambrecht, BN. Emerging functions of the unfolded protein response in immunity Nat Immunol 15, 910-919, 2014. (Epub 2014 Sep 18)
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Jouan-Lanhouet, S, Riquet, F, Duprez, L, Vanden Berghe, T, Takahashi, N, Vandenabeele, P. Necroptosis, in vivo detection in experimental disease models Semin Cell Dev Biol 35C, 2-13, 2014. (Epub 2014 Aug 23)
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Kepp, O, Senovilla, L, Vitale, I, Vacchelli, E, et al., Krysko, DV, Vandenabeele, P, et al., Zitvogel, L, Kroemer, G, Galluzzi, L. Consensus guidelines for the detection of immunogenic cell death Oncoimmunology 3, e955691, 2014. (Epub 2014 Dec 10)
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Khalil, H, Bertrand, MJ, Vandenabeele, P, Widmann, C. Caspase-3 and RasGAP: a stress-sensing survival/demise switch Trends Cell Biol 24, 83-89, 2014. (Epub 2013 Sep 2)
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Kubica, M, Hildebrand, F, Brinkman, BM, Goossens, D, Del Favero, J, Vercammen, K, Cornelis, P, Schroder, JM, Vandenabeele, P, Raes, J, Declercq, W. The skin microbiome of caspase-14 deficient mice shows mild dysbiosis Exp Dermatol 23, 561-567, 2014. (Epub 2014 May 26)
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Lambrecht, B, Guilliams, M. Monocytes find a new place to dwell in the niche of heartbreak hotel J Exp Med 211, 2136, 2014. (Epub 2014 Oct 20)
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Lambrecht, BN, Hammad, H. Allergens and the airway epithelium response: Gateway to allergic sensitization J Allergy Clin Immunol 134, 499-507, 2014. (Epub 2014 Sep)
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Lambrecht, BN, Hammad, H. Innate immune cells to the help Immunity 40, 313-314, 2014. (Epub 2014 Mar 20)
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Laukens, D, Devisscher, L, Van den Bossche, L, Hindryckx, P, Vandenbroucke, RE, Vandewynckel, YP, Cuvelier, C, Brinkman, BM, Libert, C, Vandenabeele, P, De Vos, M. Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death Lab Invest 94, 1419-1430, 2014. (Epub 2014 Oct 13)
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Lefebvre, S, Mikkola, ML. Ectodysplasin research--where to next? Semin Immunol 26, 220-228, 2014. (Epub 2014 Jun 10)
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Ley, SC, Beyaert, R. Priming IKKbeta kinase for action Biochem J 463, e1-2, 2014. (Epub 2014 Oct 1)
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Libert, C, Dejager, L. How steroids steer T cells Cell Rep 7, 938-939, 2014. (Epub 2014 May 22)
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Li, J, Gao, E, Vite, A, Yi, R, Gomez, L, Goossens, S, van Roy, F, Radice, G. Alpha-Catenins control cardiomyocyte proliferation by regulating Yap activity Circ Res 116, 70-79, 2014. (Epub 2014 Oct 10)
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Linkermann, A, Skouta, R, Himmerkus, N, Mulay, SR, Dewitz, C, De Zen, F, Prokai, A, Zuchtriegel, G, Krombach, F, Welz, PS, Weinlich, R, Vanden Berghe, T, Vandenabeele, P, Pasparakis, M, Bleich, M, Weinberg, JM, Reichel, CA, Brasen, JH, Kunzendorf, U, Anders, HJ, Stockwell, BR, Green, DR, Krautwald, S. Synchronized renal tubular cell death involves ferroptosis Proc Natl Acad Sci USA 111, 16836-16841, 2014. (Epub 2014 Nov 10)
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Lin, YC, Boone, M, Meuris, L, Lemmens, I, Van Roy, N, Soete, A, Reumers, J, Moisse, M, Plaisance, S, Drmanac, R, Chen, J, Speleman, F, Lambrechts, D, Van de Peer, Y, Tavernier, J, Callewaert, N. Genome dynamics of the human embryonic kidney 293 lineage in response to cell biology manipulations Nat Commun 5, 4767, 2014. (Epub 2014 Sep 3)
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Lybaert, L, De Vlieghere, E, De Rycke, R, Vanparijs, N, De Wever, O, De Koker, S, De Geest, BG. Bio-Hybrid Tumor Cell-Templated Capsules: A Generic Formulation Strategy for Tumor Associated Antigens in View of Immune Therapy Advanced Functional Materials 24, 7139-7150, 2014. (Epub 2014 Sep 11)
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Maes, H, Van Eygen, S, Krysko, DV, Vandenabeele, P, Nys, K, Rillaerts, K, Garg, AD, Verfaillie, T, Agostinis, P. BNIP3 supports melanoma cell migration and vasculogenic mimicry by orchestrating the actin cytoskeleton Cell Death Dis 5, e1127, 2014. (Epub 2014 Mar 13)
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Mc Guire, C, Elton, L, Wieghofer, P, Staal, J, Voet, S, Demeyer, A, Nagel, D, Krappmann, D, Prinz, M, Beyaert, R, van Loo, G. Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis J Neuroinflamm 11, 124, 2014. (Epub 2014 Jul 21)
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Mets, E, Van der Meulen, J, Van Peer, G, Boice, M, Mestdagh, P, Van de Walle, I, Lammens, T, Goossens, S, De Moerloose, B, Benoit, Y, Van Roy, N, Clappier, E, Poppe, B, Vandesompele, J, Wendel, HG, Taghon, T, Rondou, P, Soulier, J, Van Vlierberghe, P, Speleman, F. MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia Leukemia 29, 798-806, 2014. (Epub 2014 Sep 18)
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Mets, E, Van Peer, G, Van der Meulen, J, Boice, M, Taghon, T, Goossens, S, Mestdagh, P, Benoit, Y, De Moerloose, B, Van Roy, N, Poppe, B, Vandesompele, J, Wendel, HG, Van Vlierberghe, P, Speleman, F, Rondou, P. MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia Haematologica 99, 1326-1333, 2014. (Epub 2014 Jun 3)
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Meuris, L, Santens, F, Elson, G, Festjens, N, Boone, M, Dos Santos, A, Devos, S, Rousseau, F, Plets, E, Houthuys, E, Malinge, P, Magistrelli, G, Cons, L, Chatel, L, Devreese, B, Callewaert, N. GlycoDelete engineering of mammalian cells simplifies N-glycosylation of recombinant proteins Nat Biotechnol 32, 485-489, 2014. (Epub 2014 Apr 20)
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Monteiro, F, Bernal, V, Saelens, X, Lozano, AB, Bernal, C, Sevilla, A, Carrondo, MJ, Alves, PM. Metabolic profiling of insect cell lines: Unveiling cell line determinants behind system's productivity Biotechnol Bioeng 111, 816-828, 2014. (Epub 2013 Oct 28)
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Morreel, K, Saeys, Y, Dima, O, Lu, F, Van de Peer, Y, Vanholme, R, Ralph, J, Vanholme, B, Boerjan, W. Systematic structural characterization of metabolites in Arabidopsis via candidate substrate-product pair networks Plant Cell 26, 929-945, 2014. (Epub 2014 Mar 31)
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Mysara, M, Saeys, Y, Leys, N, Raes, J, Monsieurs, P. CATCh: an ensemble classifier for chimera detection in 16S rRNA sequencing studies Appl Environ Microb 81, 1573-1584, 2014. (Epub 2014 Dec 19)
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Nair, N, Rincon, MY, Evens, H, Sarcar, S, Dastidar, S, Samara-Kuko, E, Ghandeharian, O, Viecelli, HM, Thony, B, De Bleser, P, Vandendriessche, T, Chuah, MK. Computationally designed liver-specific transcriptional cis-regulatory modules and hyper-functional factor IX improve liver-targeted gene therapy for hemophilia B Blood 123, 3195-3199, 2014. (Epub 2014 Mar 17)
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Naramoto, S, Otegui, MS, Kutsuna, N, de Rycke, R, Dainobu, T, Karampelias, M, Fujimoto, M, Feraru, E, Miki, D, Fukuda, H, Nakano, A, Friml, J. Insights into the Localization and Function of the Membrane Trafficking Regulator GNOM ARF-GEF at the Golgi Apparatus in Arabidopsis Plant Cell 26, 3062-3076, 2014. (Epub 2014 Jul)
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Newton, K, Hildebrand, JM, Shen, Z, Rodriguez, D, Alvarez-Diaz, S, Petersen, S, Shah, S, Dugger, DL, Huang, C, Auwerx, J, Vandenabeele, P, Green, DR, Ashkenazi, A, Dixit, VM, Kaiser, WJ, Strasser, A, Degterev, A, Silke, J. Is SIRT2 required for necroptosis? Nature 506, E4-6, 2014. (Epub 2014 Feb 27)
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Niculaes, C, Morreel, K, Kim, H, Lu, F, McKee, LS, Ivens, B, Haustraete, J, Vanholme, B, De Rycke, R, Hertzberg, M, Fromm, J, Bulone, V, Polle, A, Ralph, J, Boerjan, W. Phenylcoumaran benzylic ether reductase prevents accumulation of compounds formed under oxidative conditions in poplar xylem Plant Cell 26, 3775-3791, 2014. (Epub 2014 Sep 19)
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Novakova, P, Hirsch, S, Feraru, E, Tejos, R, van Wijk, R, Viaene, T, Heilmann, M, Lerche, J, De Rycke, R, Feraru, MI, Grones, P, Van Montagu, M, Heilmann, I, Munnik, T, Friml, J. SAC phosphoinositide phosphatases at the tonoplast mediate vacuolar function in Arabidopsis Proceedings of the National Academy of Sciences of the United States of America 111, 2818-2823, 2014. (Epub 2014 Feb 18)
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Osorio, F, Tavernier, SJ, Hoffmann, E, Saeys, Y, Martens, L, Vetters, J, Delrue, I, De Rycke, R, Parthoens, E, Pouliot, P, Iwawaki, T, Janssens, S, Lambrecht, BN. The unfolded-protein-response sensor IRE-1alpha regulates the function of CD8alpha+ dendritic cells Nat Immunol 15, 248-257, 2014. (Epub 2014 Jan 19)
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