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Polykratis, A, van Loo, G, Xanthoulea, S, Pasparakis, M.
Conditional targeting of TRAF6 reveals opposing functions of TLR signaling in endothelial and myeloid cells in a mouse model of atherosclerosis
Circulation 126, 1739-1751 , 2012. (Epub 2012 Aug 30)

Pringels, S, Van Damme, N, De Craene, B, Pattyn, P, Ceelen, W, Peeters, M, Grooten, J.
Clinical procedure for colon carcinoma tissue sampling directly affects the cancer marker-capacity of VEGF family members
BMC Cancer 12, 515, 2012. (Epub 2012 Nov 13)

Quimbaya, M, Vandepoele, K, Raspe, E, Matthijs, M, Dhondt, S, Beemster, GT, Berx, G, De Veylder, L.
Identification of putative cancer genes through data integration and comparative genomics between plants and humans
Cell Mol Life Sci 69, 2041-2055, 2012. (Epub 2012 Jan 5)

Raspe, E, Decraene, C, Berx, G.
Gene expression profiling to dissect the complexity of cancer biology: Pitfalls and promise
Semin Cancer Biol 22, 250-260, 2012. (Epub 2012 Mar 7)

Reber, LL, Daubeuf, F, Plantinga, M, De Cauwer, L, Gerlo, S, Waelput, W, Van Calenbergh, S, Tavernier, J, Haegeman, G, Lambrecht, BN, Frossard, N, De Bosscher, K.
A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma
J Immunol 188, 3478-3487, 2012. (Epub 2012 Mar 5)

Rivetti di Val Cervo, P, Lena, AM, Nicoloso, M, Rossi, S, Mancini, M, Zhou, H, Saintigny, G, Dellambra, E, Odorisio, T, Mahe, C, Calin, GA, Candi, E, Melino, G.
p63-microRNA feedback in keratinocyte senescence
Proc Natl Acad Sci USA 109, 1133-1138, 2012. (Epub 2012 Jan 6)

Roose, K, Schotsaert, M, El Bakkouri, K, Schepens, B, Fiers, W, Saelens, X.
Cutting edge approaches towards novel and cross-protective influenza vaccines
In Development of novel vaccines. (von Gabain, A, Klade, C, eds.), Wien, Springer-Verlag, pp. 205-233, 2012. (Epub )

Rubio, N, Coupienne, I, Di Valentin, E, Heirman, I, Grooten, J, Piette, J, Agostinis, P.
Spatiotemporal autophagic degradation of oxidatively damaged organelles after photodynamic stress is amplified by mitochondrial reactive oxygen species
Autophagy 8, 1312-1324, 2012. (Epub 2012 Sep 1)

Saelens, X.
Tailor-made cleavage site attenuates influenza B
Expert Rev Vaccines 11, 159-161, 2012. (Epub 2012 Feb)

Schoonooghe, S, Leoen, J, Haustraete, J.
Production of antibody derivatives in the methylotrophic yeast Pichia pastoris
Methods Mol Biol 907, 325-340, 2012. (Epub 2012 Aug)

Schotsaert, M, Saelens, X, Leroux-Roels, G.
Influenza vaccines: T-cell responses deserve more attention
Expert Rev Vaccines 11, 949-962, 2012. (Epub 2012 Aug)

Schughart, K, Libert, C, Kas, MJ.
Strength to strength for mouse models
Nature 492, 41, 2012. (Epub 2012 Dec 6)

Sleeman, JP, Christofori, G, Fodde, R, Collard, JG, Berx, G, Decraene, C, Ruegg, C.
Concepts of metastasis in flux: The stromal progression model
Semin Cancer Biol 22, 174-186, 2012. (Epub 2012 Feb 21)

Staal, J, Beyaert, R.
A two-step activation mechanism of MALT1 paracaspase: Commentary on 'Structural determinants of MALT1 protease activity' by Wiesmann et al
J Mol Biol 419, 1-3, 2012. (Epub 2012 Mar 15)

Takahashi, N, Duprez, L, Grootjans, S, Cauwels, A, Nerinckx, W, Duhadaway, JB, Goossens, V, Roelandt, R, Van Hauwermeiren, F, Libert, C, Declercq, W, Callewaert, N, Prendergast, GC, Degterev, A, Yuan, J, Vandenabeele, P.
Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models
Cell Death Dis 3, e437, 2012. (Epub 2012 Nov 29)

Tamoutounour, S, Henri, S, Lelouard, H, de Bovis, B, de Haar, C, van der Woude, CJ, Woltman, AM, Reyal, Y, Bonnet, D, Sichien, D, Bain, CC, Mowat, AM, Reis e Sousa, C, Poulin, LF, Malissen, B, Guilliams, M.
CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis
Eur J Immunol 42, 3150-3166, 2012. (Epub 2012 Oct 17)

Tian, H, Sanders, E, Reynolds, A, Van Roy, F, Van Hengel, J.
Ocular anterior segment dysgenesis upon ablation of p120 catenin in neural crest cells
Invest Ophtalmol Vis Sci 53, 5139-5153, 2012. (Epub 2012 Jun 26)

Tiels, P, Baranova, E, Piens, K, De Visscher, C, Pynaert, G, Nerinckx, W, Stout, J, Fudalej, F, Hulpiau, P, Tannler, S, Geysens, S, Van Hecke, A, Valevska, A, Vervecken, W, Remaut, H, Callewaert, N.
A bacterial glycosidase enables mannose-6-phosphate modification and improved cellular uptake of yeast-produced recombinant human lysosomal enzymes
Nat Biotechnol 30, 1225-1231, 2012. (Epub 2012 Nov 18)

Tiwari, N, Gheldof, A, Tatari, M, Christofori, G.
EMT as the ultimate survival mechanism of cancer cells
Semin Cancer Biol 22, 194-207, 2012. (Epub 2012 Mar 8)

Tucci, P, Agostini, M, Grespi, F, Markert, EK, Terrinoni, A, Vousden, KH, Muller, PA, Dotsch, V, Kehrloesser, S, Sayan, BS, Giaccone, G, Lowe, SW, Takahashi, N, Vandenabeele, P, Knight, RA, Levine, AJ, Melino, G.
Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer
Proc Natl Acad Sci USA 109, 15312-15327, 2012. (Epub 2012 Sep 4)

Tyberghein, K, Goossens, S, Haigh, JJ, van Roy, F, van Hengel, J.
Tissue-wide overexpression of alpha-T-catenin results in aberrant trophoblast invasion but does not cause embryonic mortality in mice
Placenta 33, 554-560, 2012. (Epub 2012 Apr 23)

Van Belle, TL, Dooms, H, Boonefaes, T, Wei, XQ, Leclercq, G, Grooten, J.
IL-15 augments TCR-induced CD4(+) T cell expansion in vitro by inhibiting the suppressive function of CD25(High) CD4(+) T cells
PLoS One 7, e45299, 2012. (Epub 2012 Sep 20)

Vandenabeele, P, Bertrand, MJ.
The role of the IAP E3 ubiquitin ligases in regulating pattern-recognition receptor signalling
Nat Rev Immunol 12, 833-844, 2012. (Epub 2012 Nov 5)

Vandenabeele, P, Melino, G.
The flick of a switch: which death program to choose?
Cell Death Differ 19, 1093-1095, 2012. (Epub 2012 Jul)

Van den Bossche, J, Lamers, WH, Koehler, ES, Geuns, JM, Alhonen, L, Uimari, A, Pirnes-Karhu, S, Van Overmeire, E, Morias, Y, Brys, L, Vereecke, L, De Baetselier, P, Van Ginderachter, JA.
Pivotal Advance:Arginase-1-independent polyamine production stimulates the expression of IL-4-induced alternatively activated macrophage markers while inhibiting LPS-induced expression of inflammatory genes
J Leukoc Biol 91, 685-699, 2012. (Epub 2012 Mar 13)

Vandenbroucke, RE, Dejonckheere, E, Van Lint, P, Demeestere, D, Van Wonterghem, E, Vanlaere, I, Puimege, L, Van Hauwermeiren, F, De Rycke, R, Mc Guire, C, Campestre, C, Lopez-Otin, C, Matthys, P, Leclercq, G, Libert, C.
Matrix Metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases
J Neurosci 32, 9805-9816, 2012. (Epub 2012 Jul 18)

Vanderauwera, S, Vandenbroucke, K, Inze, A, van de Cotte, B, Muhlenbock, P, De Rycke, R, Naouar, N, Van Gaever, T, Van Montagu, MCE, Van Breusegem, F.
AtWRKY15 perturbation abolishes the mitochondrial stress response that steers osmotic stress tolerance in Arabidopsis
Proceedings of the National Academy of Sciences of the United States of America 109, 20113-20118, 2012. (Epub 2012 Oct 19)

Van de Ven, H, Vermeersch, M, Vandenbroucke, RE, Matheeussen, A, Apers, S, Weyenberg, W, De Smedt, SC, Cos, P, Maes, L, Ludwig, A.
Intracellular drug delivery in Leishmania-infected macrophages: Evaluation of saponin-loaded PLGA nanoparticles
J Drug Target 20, 142-54, 2012. (Epub 2011 Nov 14)

Vandevyver, S, Dejager, L, Libert, C.
On the trail of the glucocorticoid receptor: into the nucleus and back
Traffic 13, 364-374, 2012. (Epub 2011 Sep 27)

Vandevyver, S, Dejager, L, Van Bogaert, T, Kleyman, A, Liu, Y, Tuckermann, J, Libert, C.
Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation
J Clin Invest 122, 2130-2140, 2012. (Epub 2012 May 15)

Vanlangenakker, N, Vanden Berghe, T, Vandenabeele, P.
Many stimuli pull the necrotic trigger, an overview
Cell Death Differ 19, 75-86, 2012. (Epub 2011 Nov 11)

Vannerum, K, De Rycke, R, Pollier, J, Goossens, A, Inze, D, Vyverman, W.
Characterization of a Rabe (Ras Gene from Rat Brain E) Gtpase Expressed during Morphogenesis in the Unicellular Green Alga Micrasterias Denticulata (Zygnematophyceae, Streptophyta)
Journal of Phycology 48, 682-692, 2012. (Epub 2012 May 15)

Van Roy, F.
Cadherins
In Encyclopedia of signaling molecules. (Choi, S, ed.), New York, Springer, pp. 211-224, 2012. (Epub 2012 Aug 13)

Verhelst, J, Parthoens, E, Schepens, B, Fiers, W, Saelens, X.
Interferon-inducible Mx1 protein inhibits influenza virus by interfering with functional viral ribonucleoprotein complex assembly
J Virol 86, 13445-13455, 2012. (Epub 2012 Sep 26)

Verhelst, K, Carpentier, I, Kreike, M, Meloni, L, Verstrepen, L, Kensche, T, Dikic, I, Beyaert, R.
A20 inhibits LUBAC-mediated NF-?B activation by binding linear polyubiquitin chains via its zinc finger 7
EMBO J 31, 3845-3855, 2012. (Epub 2012 Aug 28)

Verschoor, JA, Baird, MS, Grooten, J.
Towards understanding the functional diversity of cell wall mycolic acids of Mycobacterium tuberculosis
Prog Lipid Res 51, 325-339, 2012. (Epub 2012 May 30)

Verschuere, S, Allais, L, Bracke, KR, Lippens, S, De Smet, R, Vandenabeele, P, Brusselle, GG, Cuvelier, CA.
Cigarette smoke and the terminal ileum: increased autophagy in murine follicle-associated epithelium and Peyer's patches
Histochem Cell Biol 137, 293-301, 2012. (Epub 2011 Dec 24)

Verstrepen, L, Beyaert, R.
No ubiquitin anchors and fully RIGged
Immunity 36, 897-899, 2012. (Epub 2012 Jun 29)

Wang, L, Vanhooren, V, Dewaele, S, Liu, X-E, Libert, C, Lu, F-M, Zhuang, H, Chen, CC.
Alteration of liver N-glycome in patients with hepatocellular carcinoma
Open J Gastroenterol 2, 1-8, 2012. (Epub 2012 Feb 15)

Wejda, M, Impens, F, Takahashi, N, Van Damme, P, Gevaert, K, Vandenabeele, P.
Degradomics reveals that cleavage specificity profiles of caspase-2 and effector caspases are alike
J Biol Chem 287, 33983-33995 , 2012. (Epub 2012 Jul 23)

Welsch, L, Welsch, T, Dovzhanskiy, DI, Felix, K, Giese, NA, Krysko, DV, Werner, J.
Impact of the histone deacetylase inhibitor 4-phenylbutyrate on the clearance of apoptotic pancreatic carcinoma cells by human macrophages
Int J Oncol 40, 427-435, 2012. (Epub 2011 Oct 21)

Willart, MA, Deswarte, K, Pouliot, P, Braun, H, Beyaert, R, Lambrecht, BN, Hammad, H.
Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33
J Exp Med 209, 1505-1517, 2012. (Epub 2012 Jul 16)

Willart, MA, van Nimwegen, M, Grefhorst, A, Hammad, H, Moons, L, Hoogsteden, HC, Lambrecht, BN, Kleinjan, A.
Ursodeoxycholic acid suppresses eosinophilic airway inflammation by inhibiting the function of dendritic cells through the nuclear farnesoid X receptor
67 1501-1510, Allergy, 2012. (Epub 2012 Sep 25)

Willenborg, S, Lucas, T, van Loo, G, Knipper, JA, Krieg, T, Haase, I, Brachvogel, B, Hammerschmidt, M, Nagy, A, Ferrara, N, Pasparakis, M, Eming, SA.
CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair
Blood 120, 613-325, 2012. (Epub 2012 May 10)

Wirawan, E, Lippens, S, Vanden Berghe, T, Romagnoli, A, Fimia, GM, Piacentini, M, Vandenabeele, P.
Beclin1: A role in membrane dynamics and beyond
Autophagy 8, , 2012. (Epub 2012 Jan 1)

Wirawan, E, Vanden Berghe, T, Lippens, S, Agostinis, P, Vandenabeele, P.
Autophagy: for better or for worse
Cell Res 22, 43-61, 2012. (Epub 2011 Sep 13)

Wolf, MJ, Hoos, A, Bauer, J, Boettcher, S, Knust, M, Weber, A, Simonavicius, N, Schneider, C, Lang, M, Sturzl, M, Croner, RS, Konrad, A, Manz, MG, Moch, H, Aguzzi, A, van Loo, G, Pasparakis, M, Prinz, M, Borsig, L, Heikenwalder, M.
Endothelial CCR2 signaling induced by colon carcinoma cells licenses extravasation via the JAK2-Stat5 and p38MAPK pathway
Cancer Cell 22, 91-105, 2012. (Epub 2012 Jul 10)

Ydens, E, Cauwels, A, Asselbergh, B, Goethals, S, Peeraer, L, Lornet, G, Almeida-Souza, L, Van Ginderachter, JA, Timmerman, V, Janssens, S.
Acute injury in the peripheral nervous system triggers an alternative macrophage response
J Neuroinflammation 9, 176, 2012. (Epub 2012 Jul 20)

Abdulkhalek, S, Amith, SR, Franchuk, SL, Jayanth, P, Guo, M, Finlay, T, Gilmour, A, Guzzo, C, Gee, K, Beyaert, R, Szewczuk, MR.
Neu1 sialidase and matrix metalloproteinase-9 cross-talk is essential for TOLL-like receptor activation and cellular signaling
J Biol Chem 286, 36532-36549, 2011. (Epub 2011 Aug 26)

Al Atalah, B, Fouquaert, E, Vanderschaeghe, D, Proost, P, Balzarini, J, Smith, DF, Rouge, P, Lasanajak, Y, Callewaert, N, Van Damme, EJ.
Expression analysis of the nucleocytoplasmic lectin "Orysata" from rice in Pichia pastoris
FEBS J 12, 2064-2079, 2011. (Epub 2011 Apr 11)

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