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Li, J, Goossens, S, van Hengel, J, Gao, E, Cheng, L, Tyberghein, K, Shang, X, De Rycke, R, van Roy, F, Radice, G.
Loss of alpha-T-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia
J Cell Sci 125, 1058-1067, 2012. (Epub 2012 Mar 15)

Loeder, S, Schirmer, M, Schoeneberger, H, Cristofanon, S, Leibacher, J, Vanlangenakker, N, Bertrand, MJ, Vandenabeele, P, Jeremias, I, Debatin, KM, Fulda, S.
RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis
Leukemia 26, 1020-1029, 2012. (Epub 2011 Dec 16)

Lucitti, JL, Mackey, JK, Morrison, JC, Haigh, JJ, Adams, RH, Faber, JE.
Formation of the collateral circulation is regulated by Vascular Endothelial Growth Factor-A and a disintegrin and metalloprotease family members 10 and 17
Circ Res 111, 1539-1550, 2012. (Epub 2012 Sep 10)

Maddens, B, Vandendriessche, B, Demon, D, Vanholder, R, Chiers, K, Cauwels, A, Meyer, E.
Severity of sepsis-induced acute kidney injury in a novel mouse model is age dependent
Crit Care Med 40, 2638-2646, 2012. (Epub 2012 Jun 28)

Maelfait, J, Beyaert, R.
Emerging role of ubiquitination in antiviral RIG-I signaling
Microbiol Mol Biol Rev 76, 33-45, 2012. (Epub 2012 Mar)

Maelfait, J, Roose, K, Bogaert, P, Sze, M, Saelens, X, Pasparakis, M, Carpentier, I, van Loo, G, Beyaert, R.
A20 (Tnfaip3) deficiency in myeloid cells protects against Influenza A virus infection
PLoS Pathog 8, e1002570, 2012. (Epub 2012 Mar 1)

Maes, C, Araldi, E, Haigh, K, Khatri, R, Van Looveren, R, Giaccia, AJ, Haigh, JJ, Carmeliet, G, Schipani, E.
VEGF-independent cell-autonomous functions of HIF-1alpha regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival
J Bone Miner Res 27, 596-609, 2012. (Epub 2011 Dec 8)

Matalova, E, Vanden Berghe, T, Svandova, E, Vandenabeele, P, Healy, C, Sharpe, PT, Tucker, AS.
Caspase-7 in molar tooth development
Arch Oral Biol 57, 1474-1481, 2012. (Epub 2012 Aug 31)

Mengozzi, M, Cervellini, I, Villa, P, Erbayraktar, Z, Gokmen, N, Yilmaz, O, Erbayraktar, S, Manohasandra, M, Van Hummelen, P, Vandenabeele, P, Chernajovsky, Y, Annenkov, A, Ghezzi, P.
Erythropoietin-induced changes in brain gene expression reveal induction of synaptic plasticity genes in experimental stroke
Proc Natl Acad Sci USA 109, 9617-9622, 2012. (Epub 2012 May 29)

Miguez, A, Ducret, S, Di Meglio, T, Parras, C, Hmidan, H, Haton, C, Sekizar, S, Manniou, A, Vidal, M, Keveler, A, Nyabi, O, Haigh, J, Zalc, B, Rijli, F, Thomas, J-L.
Opposing roles for Hoxa2 and Hoxb2 in hindbrain oligodendrocyte patterning
J Neurosci 32, 17172-17185, 2012. (Epub 2012 Nov 28)

Munoz, WA, Kloc, M, Cho, K, Lee, M, Hofmann, I, Sater, A, Vleminckx, K, McCrea, PD.
Plakophilin-3 is required for late embryonic amphibian development, exhibiting roles in ectodermal and neural tissues
PLoS One 7, e34342, 2012. (Epub 2012 Apr 5)

Naessens, T, Vander Beken, S, Bogaert, P, Van Rooijen, N, Lienenklaus, S, Weiss, S, De Koker, S, Grooten, J.
Innate imprinting of murine resident alveolar macrophages by allergic bronchial inflammation causes a switch from hypo- to hyperinflammatory reactivity
Am J Pathol 181, 174-184, 2012. (Epub 2012 May 18)

Nagels, B, Van Damme, EJ, Callewaert, N, Weterings, K.
Introduction of tri-antennary N-glycans in Arabidopsis thaliana plants
Plant Sci 185-186, 161-168, 2012. (Epub 2011 Oct 10)

Nagels, B, Van Damme, EJ, Callewaert, N, Zabeau, L, Tavernier, J, Delanghe, JR, Boets, A, Castilho, A, Weterings, K.
Biologically active, MagnICON(R)-expressed EPO-Fc from stably transformed Nicotiana benthamiana plants presenting tetra-antennary N-glycan structures
J Biotechnol 160, 242-250, 2012. (Epub 2012 Mar 16)

Nagels, B, Weterings, K, Callewaert, N, Van Damme, EJM.
Production of plant made pharmaceuticals: from plant host to functional protein
Crit Rev Plant Sci 31, 148-180, 2012. (Epub 2012 Mar 8)

Neyt, K, Perros, F, Geurtsvankessel, CH, Hammad, H, Lambrecht, BN.
Tertiary lymphoid organs in infection and autoimmunity
Trends Immunol 33, 297-305, 2012. (Epub 2012 May 21)

Nunez, NG, Andreani, V, Crespo, MI, Nocera, DA, Breser, ML, Moron, G, Dejager, L, Libert, C, Rivero, V, Maccioni, M.
IFN beta produced by TLR4-activated tumor cells is involved in improving the antitumoral immune response
Cancer Res 72, 592-603, 2012. (Epub 2011 Dec 2)

Oh, HJ, Abraham, LS, van Hengel, J, Stove, C, Proszynski, TJ, Gevaert, K, Dimario, JX, Sanes, JR, van Roy, F, Kim, H.
The interaction of alpha-catulin with dystrobrevin contributes to the integrity of the dystrophin complex in muscle
J Biol Chem 287, 21717-21728, 2012. (Epub 2012 May 10)

Orofino Kreuger, MR, Grootjans, S, Biavatti, MW, Vandenabeele, P, D'Herde, K.
Sesquiterpene lactones as drugs with multiple targets in cancer treatment: focus on parthenolide
Anticancer Drugs 23, 883-896, 2012. (Epub 2012 Jul 11)

Pagliarini, V, Wirawan, E, Romagnoli, A, Ciccosanti, F, Lisi, G, Lippens, S, Cecconi, F, Fimia, GM, Vandenabeele, P, Corazzari, M, Piacentini, M.
Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response
Cell Death Differ 19, 1495-1504, 2012. (Epub 2012 Mar 23)

Pieters, T, Haenebalcke, L, Hochepied, T, D'Hont, J, Haigh, JJ, van Roy, F, van Hengel, J.
Efficient and user-friendly pluripotin-based derivation of mouse embryonic stem cells
Stem Cell Rev Rep 8, 768-778, 2012. (Epub 2011 Oct 20)

Pieters, T, Van Hengel, J, Van Roy, F.
Functions of p120ctn in development and disease
Front Biosci 17, 760-783, 2012. (Epub 2012 Jan 1)

Pieters, T, Van Roy, F, Van Hengel, J.
Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling
Front Biosci 17, 1669-1694, 2012. (Epub 2012 Jan 1)

Pleines, I, Hagedorn, I, Gupta, S, May, F, Chakarova, L, van Hengel, J, Offermanns, S, Krohne, G, Kleinschnitz, C, Brakebusch, C, Nieswandt, B.
Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis
Blood 119, 1054-1063, 2012. (Epub 2011 Nov 1)

Polykratis, A, van Loo, G, Xanthoulea, S, Pasparakis, M.
Conditional targeting of TRAF6 reveals opposing functions of TLR signaling in endothelial and myeloid cells in a mouse model of atherosclerosis
Circulation 126, 1739-1751 , 2012. (Epub 2012 Aug 30)

Pringels, S, Van Damme, N, De Craene, B, Pattyn, P, Ceelen, W, Peeters, M, Grooten, J.
Clinical procedure for colon carcinoma tissue sampling directly affects the cancer marker-capacity of VEGF family members
BMC Cancer 12, 515, 2012. (Epub 2012 Nov 13)

Quimbaya, M, Vandepoele, K, Raspe, E, Matthijs, M, Dhondt, S, Beemster, GT, Berx, G, De Veylder, L.
Identification of putative cancer genes through data integration and comparative genomics between plants and humans
Cell Mol Life Sci 69, 2041-2055, 2012. (Epub 2012 Jan 5)

Raspe, E, Decraene, C, Berx, G.
Gene expression profiling to dissect the complexity of cancer biology: Pitfalls and promise
Semin Cancer Biol 22, 250-260, 2012. (Epub 2012 Mar 7)

Reber, LL, Daubeuf, F, Plantinga, M, De Cauwer, L, Gerlo, S, Waelput, W, Van Calenbergh, S, Tavernier, J, Haegeman, G, Lambrecht, BN, Frossard, N, De Bosscher, K.
A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma
J Immunol 188, 3478-3487, 2012. (Epub 2012 Mar 5)

Rivetti di Val Cervo, P, Lena, AM, Nicoloso, M, Rossi, S, Mancini, M, Zhou, H, Saintigny, G, Dellambra, E, Odorisio, T, Mahe, C, Calin, GA, Candi, E, Melino, G.
p63-microRNA feedback in keratinocyte senescence
Proc Natl Acad Sci USA 109, 1133-1138, 2012. (Epub 2012 Jan 6)

Roose, K, Schotsaert, M, El Bakkouri, K, Schepens, B, Fiers, W, Saelens, X.
Cutting edge approaches towards novel and cross-protective influenza vaccines
In Development of novel vaccines. (von Gabain, A, Klade, C, eds.), Wien, Springer-Verlag, pp. 205-233, 2012. (Epub )

Rubio, N, Coupienne, I, Di Valentin, E, Heirman, I, Grooten, J, Piette, J, Agostinis, P.
Spatiotemporal autophagic degradation of oxidatively damaged organelles after photodynamic stress is amplified by mitochondrial reactive oxygen species
Autophagy 8, 1312-1324, 2012. (Epub 2012 Sep 1)

Saelens, X.
Tailor-made cleavage site attenuates influenza B
Expert Rev Vaccines 11, 159-161, 2012. (Epub 2012 Feb)

Schoonooghe, S, Leoen, J, Haustraete, J.
Production of antibody derivatives in the methylotrophic yeast Pichia pastoris
Methods Mol Biol 907, 325-340, 2012. (Epub 2012 Aug)

Schotsaert, M, Saelens, X, Leroux-Roels, G.
Influenza vaccines: T-cell responses deserve more attention
Expert Rev Vaccines 11, 949-962, 2012. (Epub 2012 Aug)

Schughart, K, Libert, C, Kas, MJ.
Strength to strength for mouse models
Nature 492, 41, 2012. (Epub 2012 Dec 6)

Sleeman, JP, Christofori, G, Fodde, R, Collard, JG, Berx, G, Decraene, C, Ruegg, C.
Concepts of metastasis in flux: The stromal progression model
Semin Cancer Biol 22, 174-186, 2012. (Epub 2012 Feb 21)

Staal, J, Beyaert, R.
A two-step activation mechanism of MALT1 paracaspase: Commentary on 'Structural determinants of MALT1 protease activity' by Wiesmann et al
J Mol Biol 419, 1-3, 2012. (Epub 2012 Mar 15)

Takahashi, N, Duprez, L, Grootjans, S, Cauwels, A, Nerinckx, W, Duhadaway, JB, Goossens, V, Roelandt, R, Van Hauwermeiren, F, Libert, C, Declercq, W, Callewaert, N, Prendergast, GC, Degterev, A, Yuan, J, Vandenabeele, P.
Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models
Cell Death Dis 3, e437, 2012. (Epub 2012 Nov 29)

Tamoutounour, S, Henri, S, Lelouard, H, de Bovis, B, de Haar, C, van der Woude, CJ, Woltman, AM, Reyal, Y, Bonnet, D, Sichien, D, Bain, CC, Mowat, AM, Reis e Sousa, C, Poulin, LF, Malissen, B, Guilliams, M.
CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis
Eur J Immunol 42, 3150-3166, 2012. (Epub 2012 Oct 17)

Tian, H, Sanders, E, Reynolds, A, Van Roy, F, Van Hengel, J.
Ocular anterior segment dysgenesis upon ablation of p120 catenin in neural crest cells
Invest Ophtalmol Vis Sci 53, 5139-5153, 2012. (Epub 2012 Jun 26)

Tiels, P, Baranova, E, Piens, K, De Visscher, C, Pynaert, G, Nerinckx, W, Stout, J, Fudalej, F, Hulpiau, P, Tannler, S, Geysens, S, Van Hecke, A, Valevska, A, Vervecken, W, Remaut, H, Callewaert, N.
A bacterial glycosidase enables mannose-6-phosphate modification and improved cellular uptake of yeast-produced recombinant human lysosomal enzymes
Nat Biotechnol 30, 1225-1231, 2012. (Epub 2012 Nov 18)

Tiwari, N, Gheldof, A, Tatari, M, Christofori, G.
EMT as the ultimate survival mechanism of cancer cells
Semin Cancer Biol 22, 194-207, 2012. (Epub 2012 Mar 8)

Tucci, P, Agostini, M, Grespi, F, Markert, EK, Terrinoni, A, Vousden, KH, Muller, PA, Dotsch, V, Kehrloesser, S, Sayan, BS, Giaccone, G, Lowe, SW, Takahashi, N, Vandenabeele, P, Knight, RA, Levine, AJ, Melino, G.
Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer
Proc Natl Acad Sci USA 109, 15312-15327, 2012. (Epub 2012 Sep 4)

Tyberghein, K, Goossens, S, Haigh, JJ, van Roy, F, van Hengel, J.
Tissue-wide overexpression of alpha-T-catenin results in aberrant trophoblast invasion but does not cause embryonic mortality in mice
Placenta 33, 554-560, 2012. (Epub 2012 Apr 23)

Van Belle, TL, Dooms, H, Boonefaes, T, Wei, XQ, Leclercq, G, Grooten, J.
IL-15 augments TCR-induced CD4(+) T cell expansion in vitro by inhibiting the suppressive function of CD25(High) CD4(+) T cells
PLoS One 7, e45299, 2012. (Epub 2012 Sep 20)

Vandenabeele, P, Bertrand, MJ.
The role of the IAP E3 ubiquitin ligases in regulating pattern-recognition receptor signalling
Nat Rev Immunol 12, 833-844, 2012. (Epub 2012 Nov 5)

Vandenabeele, P, Melino, G.
The flick of a switch: which death program to choose?
Cell Death Differ 19, 1093-1095, 2012. (Epub 2012 Jul)

Van den Bossche, J, Lamers, WH, Koehler, ES, Geuns, JM, Alhonen, L, Uimari, A, Pirnes-Karhu, S, Van Overmeire, E, Morias, Y, Brys, L, Vereecke, L, De Baetselier, P, Van Ginderachter, JA.
Pivotal Advance:Arginase-1-independent polyamine production stimulates the expression of IL-4-induced alternatively activated macrophage markers while inhibiting LPS-induced expression of inflammatory genes
J Leukoc Biol 91, 685-699, 2012. (Epub 2012 Mar 13)

Vandenbroucke, RE, Dejonckheere, E, Van Lint, P, Demeestere, D, Van Wonterghem, E, Vanlaere, I, Puimege, L, Van Hauwermeiren, F, De Rycke, R, Mc Guire, C, Campestre, C, Lopez-Otin, C, Matthys, P, Leclercq, G, Libert, C.
Matrix Metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases
J Neurosci 32, 9805-9816, 2012. (Epub 2012 Jul 18)

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