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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Li, J, Goossens, S, van Hengel, J, Gao, E, Cheng, L, Tyberghein, K, Shang, X, De Rycke, R, van Roy, F, Radice, G. Loss of alpha-T-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia J Cell Sci 125, 1058-1067, 2012. (Epub 2012 Mar 15) 
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Loeder, S, Schirmer, M, Schoeneberger, H, Cristofanon, S, Leibacher, J, Vanlangenakker, N, Bertrand, MJ, Vandenabeele, P, Jeremias, I, Debatin, KM, Fulda, S. RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis Leukemia 26, 1020-1029, 2012. (Epub 2011 Dec 16)
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Lucitti, JL, Mackey, JK, Morrison, JC, Haigh, JJ, Adams, RH, Faber, JE. Formation of the collateral circulation is regulated by Vascular Endothelial Growth Factor-A and a disintegrin and metalloprotease family members 10 and 17 Circ Res 111, 1539-1550, 2012. (Epub 2012 Sep 10)
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Maddens, B, Vandendriessche, B, Demon, D, Vanholder, R, Chiers, K, Cauwels, A, Meyer, E. Severity of sepsis-induced acute kidney injury in a novel mouse model is age dependent Crit Care Med 40, 2638-2646, 2012. (Epub 2012 Jun 28)
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Maelfait, J, Beyaert, R. Emerging role of ubiquitination in antiviral RIG-I signaling Microbiol Mol Biol Rev 76, 33-45, 2012. (Epub 2012 Mar)
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Maelfait, J, Roose, K, Bogaert, P, Sze, M, Saelens, X, Pasparakis, M, Carpentier, I, van Loo, G, Beyaert, R. A20 (Tnfaip3) deficiency in myeloid cells protects against Influenza A virus infection PLoS Pathog 8, e1002570, 2012. (Epub 2012 Mar 1)
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Maes, C, Araldi, E, Haigh, K, Khatri, R, Van Looveren, R, Giaccia, AJ, Haigh, JJ, Carmeliet, G, Schipani, E. VEGF-independent cell-autonomous functions of HIF-1alpha regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival J Bone Miner Res 27, 596-609, 2012. (Epub 2011 Dec 8)
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Matalova, E, Vanden Berghe, T, Svandova, E, Vandenabeele, P, Healy, C, Sharpe, PT, Tucker, AS. Caspase-7 in molar tooth development Arch Oral Biol 57, 1474-1481, 2012. (Epub 2012 Aug 31)
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Mengozzi, M, Cervellini, I, Villa, P, Erbayraktar, Z, Gokmen, N, Yilmaz, O, Erbayraktar, S, Manohasandra, M, Van Hummelen, P, Vandenabeele, P, Chernajovsky, Y, Annenkov, A, Ghezzi, P. Erythropoietin-induced changes in brain gene expression reveal induction of synaptic plasticity genes in experimental stroke Proc Natl Acad Sci USA 109, 9617-9622, 2012. (Epub 2012 May 29)
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Miguez, A, Ducret, S, Di Meglio, T, Parras, C, Hmidan, H, Haton, C, Sekizar, S, Manniou, A, Vidal, M, Keveler, A, Nyabi, O, Haigh, J, Zalc, B, Rijli, F, Thomas, J-L. Opposing roles for Hoxa2 and Hoxb2 in hindbrain oligodendrocyte patterning J Neurosci 32, 17172-17185, 2012. (Epub 2012 Nov 28)
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Munoz, WA, Kloc, M, Cho, K, Lee, M, Hofmann, I, Sater, A, Vleminckx, K, McCrea, PD. Plakophilin-3 is required for late embryonic amphibian development, exhibiting roles in ectodermal and neural tissues PLoS One 7, e34342, 2012. (Epub 2012 Apr 5)
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Naessens, T, Vander Beken, S, Bogaert, P, Van Rooijen, N, Lienenklaus, S, Weiss, S, De Koker, S, Grooten, J. Innate imprinting of murine resident alveolar macrophages by allergic bronchial inflammation causes a switch from hypo- to hyperinflammatory reactivity Am J Pathol 181, 174-184, 2012. (Epub 2012 May 18)
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Nagels, B, Van Damme, EJ, Callewaert, N, Weterings, K. Introduction of tri-antennary N-glycans in Arabidopsis thaliana plants Plant Sci 185-186, 161-168, 2012. (Epub 2011 Oct 10)
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Nagels, B, Van Damme, EJ, Callewaert, N, Zabeau, L, Tavernier, J, Delanghe, JR, Boets, A, Castilho, A, Weterings, K. Biologically active, MagnICON(R)-expressed EPO-Fc from stably transformed Nicotiana benthamiana plants presenting tetra-antennary N-glycan structures J Biotechnol 160, 242-250, 2012. (Epub 2012 Mar 16)
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Nagels, B, Weterings, K, Callewaert, N, Van Damme, EJM. Production of plant made pharmaceuticals: from plant host to functional protein Crit Rev Plant Sci 31, 148-180, 2012. (Epub 2012 Mar 8)
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Neyt, K, Perros, F, Geurtsvankessel, CH, Hammad, H, Lambrecht, BN. Tertiary lymphoid organs in infection and autoimmunity Trends Immunol 33, 297-305, 2012. (Epub 2012 May 21)
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Nunez, NG, Andreani, V, Crespo, MI, Nocera, DA, Breser, ML, Moron, G, Dejager, L, Libert, C, Rivero, V, Maccioni, M. IFN beta produced by TLR4-activated tumor cells is involved in improving the antitumoral immune response Cancer Res 72, 592-603, 2012. (Epub 2011 Dec 2)
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Oh, HJ, Abraham, LS, van Hengel, J, Stove, C, Proszynski, TJ, Gevaert, K, Dimario, JX, Sanes, JR, van Roy, F, Kim, H. The interaction of alpha-catulin with dystrobrevin contributes to the integrity of the dystrophin complex in muscle J Biol Chem 287, 21717-21728, 2012. (Epub 2012 May 10)
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Orofino Kreuger, MR, Grootjans, S, Biavatti, MW, Vandenabeele, P, D'Herde, K. Sesquiterpene lactones as drugs with multiple targets in cancer treatment: focus on parthenolide Anticancer Drugs 23, 883-896, 2012. (Epub 2012 Jul 11)
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Pagliarini, V, Wirawan, E, Romagnoli, A, Ciccosanti, F, Lisi, G, Lippens, S, Cecconi, F, Fimia, GM, Vandenabeele, P, Corazzari, M, Piacentini, M. Proteolysis of Ambra1 during apoptosis has a role in the inhibition of the autophagic pro-survival response Cell Death Differ 19, 1495-1504, 2012. (Epub 2012 Mar 23)
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Pieters, T, Haenebalcke, L, Hochepied, T, D'Hont, J, Haigh, JJ, van Roy, F, van Hengel, J. Efficient and user-friendly pluripotin-based derivation of mouse embryonic stem cells Stem Cell Rev Rep 8, 768-778, 2012. (Epub 2011 Oct 20)
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Pieters, T, Van Hengel, J, Van Roy, F. Functions of p120ctn in development and disease Front Biosci 17, 760-783, 2012. (Epub 2012 Jan 1)
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Pieters, T, Van Roy, F, Van Hengel, J. Functions of p120ctn isoforms in cell-cell adhesion and intracellular signaling Front Biosci 17, 1669-1694, 2012. (Epub 2012 Jan 1)
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Pleines, I, Hagedorn, I, Gupta, S, May, F, Chakarova, L, van Hengel, J, Offermanns, S, Krohne, G, Kleinschnitz, C, Brakebusch, C, Nieswandt, B. Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis Blood 119, 1054-1063, 2012. (Epub 2011 Nov 1)
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Polykratis, A, van Loo, G, Xanthoulea, S, Pasparakis, M. Conditional targeting of TRAF6 reveals opposing functions of TLR signaling in endothelial and myeloid cells in a mouse model of atherosclerosis Circulation 126, 1739-1751 , 2012. (Epub 2012 Aug 30)
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Pringels, S, Van Damme, N, De Craene, B, Pattyn, P, Ceelen, W, Peeters, M, Grooten, J. Clinical procedure for colon carcinoma tissue sampling directly affects the cancer marker-capacity of VEGF family members BMC Cancer 12, 515, 2012. (Epub 2012 Nov 13)
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Quimbaya, M, Vandepoele, K, Raspe, E, Matthijs, M, Dhondt, S, Beemster, GT, Berx, G, De Veylder, L. Identification of putative cancer genes through data integration and comparative genomics between plants and humans Cell Mol Life Sci 69, 2041-2055, 2012. (Epub 2012 Jan 5)
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Raspe, E, Decraene, C, Berx, G. Gene expression profiling to dissect the complexity of cancer biology: Pitfalls and promise Semin Cancer Biol 22, 250-260, 2012. (Epub 2012 Mar 7)
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Reber, LL, Daubeuf, F, Plantinga, M, De Cauwer, L, Gerlo, S, Waelput, W, Van Calenbergh, S, Tavernier, J, Haegeman, G, Lambrecht, BN, Frossard, N, De Bosscher, K. A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma J Immunol 188, 3478-3487, 2012. (Epub 2012 Mar 5)
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Rivetti di Val Cervo, P, Lena, AM, Nicoloso, M, Rossi, S, Mancini, M, Zhou, H, Saintigny, G, Dellambra, E, Odorisio, T, Mahe, C, Calin, GA, Candi, E, Melino, G. p63-microRNA feedback in keratinocyte senescence Proc Natl Acad Sci USA 109, 1133-1138, 2012. (Epub 2012 Jan 6)
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Roose, K, Schotsaert, M, El Bakkouri, K, Schepens, B, Fiers, W, Saelens, X. Cutting edge approaches towards novel and cross-protective influenza vaccines In Development of novel vaccines. (von Gabain, A, Klade, C, eds.), Wien, Springer-Verlag, pp. 205-233, 2012. (Epub )
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Rubio, N, Coupienne, I, Di Valentin, E, Heirman, I, Grooten, J, Piette, J, Agostinis, P. Spatiotemporal autophagic degradation of oxidatively damaged organelles after photodynamic stress is amplified by mitochondrial reactive oxygen species Autophagy 8, 1312-1324, 2012. (Epub 2012 Sep 1)
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Saelens, X. Tailor-made cleavage site attenuates influenza B Expert Rev Vaccines 11, 159-161, 2012. (Epub 2012 Feb)
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Schoonooghe, S, Leoen, J, Haustraete, J. Production of antibody derivatives in the methylotrophic yeast Pichia pastoris Methods Mol Biol 907, 325-340, 2012. (Epub 2012 Aug)
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Schotsaert, M, Saelens, X, Leroux-Roels, G. Influenza vaccines: T-cell responses deserve more attention Expert Rev Vaccines 11, 949-962, 2012. (Epub 2012 Aug)
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Schughart, K, Libert, C, Kas, MJ. Strength to strength for mouse models Nature 492, 41, 2012. (Epub 2012 Dec 6)
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Sleeman, JP, Christofori, G, Fodde, R, Collard, JG, Berx, G, Decraene, C, Ruegg, C. Concepts of metastasis in flux: The stromal progression model Semin Cancer Biol 22, 174-186, 2012. (Epub 2012 Feb 21)
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Staal, J, Beyaert, R. A two-step activation mechanism of MALT1 paracaspase: Commentary on 'Structural determinants of MALT1 protease activity' by Wiesmann et al J Mol Biol 419, 1-3, 2012. (Epub 2012 Mar 15)
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Takahashi, N, Duprez, L, Grootjans, S, Cauwels, A, Nerinckx, W, Duhadaway, JB, Goossens, V, Roelandt, R, Van Hauwermeiren, F, Libert, C, Declercq, W, Callewaert, N, Prendergast, GC, Degterev, A, Yuan, J, Vandenabeele, P. Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models Cell Death Dis 3, e437, 2012. (Epub 2012 Nov 29)
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Tamoutounour, S, Henri, S, Lelouard, H, de Bovis, B, de Haar, C, van der Woude, CJ, Woltman, AM, Reyal, Y, Bonnet, D, Sichien, D, Bain, CC, Mowat, AM, Reis e Sousa, C, Poulin, LF, Malissen, B, Guilliams, M. CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis Eur J Immunol 42, 3150-3166, 2012. (Epub 2012 Oct 17)
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Tian, H, Sanders, E, Reynolds, A, Van Roy, F, Van Hengel, J. Ocular anterior segment dysgenesis upon ablation of p120 catenin in neural crest cells Invest Ophtalmol Vis Sci 53, 5139-5153, 2012. (Epub 2012 Jun 26)
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Tiels, P, Baranova, E, Piens, K, De Visscher, C, Pynaert, G, Nerinckx, W, Stout, J, Fudalej, F, Hulpiau, P, Tannler, S, Geysens, S, Van Hecke, A, Valevska, A, Vervecken, W, Remaut, H, Callewaert, N. A bacterial glycosidase enables mannose-6-phosphate modification and improved cellular uptake of yeast-produced recombinant human lysosomal enzymes Nat Biotechnol 30, 1225-1231, 2012. (Epub 2012 Nov 18)
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Tiwari, N, Gheldof, A, Tatari, M, Christofori, G. EMT as the ultimate survival mechanism of cancer cells Semin Cancer Biol 22, 194-207, 2012. (Epub 2012 Mar 8)
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Tucci, P, Agostini, M, Grespi, F, Markert, EK, Terrinoni, A, Vousden, KH, Muller, PA, Dotsch, V, Kehrloesser, S, Sayan, BS, Giaccone, G, Lowe, SW, Takahashi, N, Vandenabeele, P, Knight, RA, Levine, AJ, Melino, G. Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer Proc Natl Acad Sci USA 109, 15312-15327, 2012. (Epub 2012 Sep 4)
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Tyberghein, K, Goossens, S, Haigh, JJ, van Roy, F, van Hengel, J. Tissue-wide overexpression of alpha-T-catenin results in aberrant trophoblast invasion but does not cause embryonic mortality in mice Placenta 33, 554-560, 2012. (Epub 2012 Apr 23)
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Van Belle, TL, Dooms, H, Boonefaes, T, Wei, XQ, Leclercq, G, Grooten, J. IL-15 augments TCR-induced CD4(+) T cell expansion in vitro by inhibiting the suppressive function of CD25(High) CD4(+) T cells PLoS One 7, e45299, 2012. (Epub 2012 Sep 20)
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Vandenabeele, P, Bertrand, MJ. The role of the IAP E3 ubiquitin ligases in regulating pattern-recognition receptor signalling Nat Rev Immunol 12, 833-844, 2012. (Epub 2012 Nov 5)
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Vandenabeele, P, Melino, G. The flick of a switch: which death program to choose? Cell Death Differ 19, 1093-1095, 2012. (Epub 2012 Jul)
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Van den Bossche, J, Lamers, WH, Koehler, ES, Geuns, JM, Alhonen, L, Uimari, A, Pirnes-Karhu, S, Van Overmeire, E, Morias, Y, Brys, L, Vereecke, L, De Baetselier, P, Van Ginderachter, JA. Pivotal Advance:Arginase-1-independent polyamine production stimulates the expression of IL-4-induced alternatively activated macrophage markers while inhibiting LPS-induced expression of inflammatory genes J Leukoc Biol 91, 685-699, 2012. (Epub 2012 Mar 13)
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Vandenbroucke, RE, Dejonckheere, E, Van Lint, P, Demeestere, D, Van Wonterghem, E, Vanlaere, I, Puimege, L, Van Hauwermeiren, F, De Rycke, R, Mc Guire, C, Campestre, C, Lopez-Otin, C, Matthys, P, Leclercq, G, Libert, C. Matrix Metalloprotease 8-dependent extracellular matrix cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases J Neurosci 32, 9805-9816, 2012. (Epub 2012 Jul 18)
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