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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Cannoodt, R, Saelens, W, Deconinck, L, Saeys, Y. Spearheading future omics analyses using dyngen, a multi-modal simulator of single cells Nat Commun 12, 3942, 2021. (Epub 2021 Jun 24) 
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Canti, L, Chrzanowska, A, Doglio, MG, Martina, L, Van Den Bossche, T. Research culture: science from bench to society Biol Open 10, bio058919, 2021. (Epub 2021 Aug 15)
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Carbo, JM, Leon, TE, Font-Diaz, J, De la Rosa, JV, Castrillo, A, Picard, FR, Staudenraus, D, Huber, M, Cedo, L, Escola-Gil, JC, Campos, L, Bakiri, L, Wagner, EF, Caelles, C, Stratmann, T, Van Ginderachter, JA, Valledor, AF. Pharmacological activation of LXR alters the expression profile of tumor-associated macrophages and the abundance of regulatory T cells in the tumor microenvironment Cancer Res 81, 968-985, 2021. (Epub 2020 Dec 23)
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Carron, P, De Craemer, AS, Renson, T, Colman, R, Elewaut, D, Van den Bosch, F. TNFi-induced sustained clinical remission in peripheral spondyloarthritis patients cannot be maintained with a step-down strategy based on methotrexate Rheumatology (Oxford) 60, 4880-4883, 2021. (Epub 2021 Oct 21)
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Catrysse, L, Maes, B, Mehrotra, P, Martens, A, Hoste, E, Martens, L, Maueroder, C, Remmerie, A, Bujko, A, Slowicka, K, Sze, M, Vikkula, H, Ghesquiere, B, Scott, CL, Saeys, Y, van de Sluis, B, Ravichandran, K, Janssens, S, van Loo, G. A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism Cell Rep 36, 109748, 2021. (Epub 2021 Sep 21)
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Claeys, W, Van Hoecke, L, Lefere, S, Geerts, A, Verhelst, X, Van Vlierberghe, H, Degroote, H, Devisscher, L, Vandenbroucke, RE, Van Steenkiste, C. The neurogliovascular unit in hepatic encephalopathy JHEP Rep 3, 100352, 2021. (Epub 2021 Aug 11 )
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Cloots, E, Debeuf, N, Deswarte, K, Fayazpour, F, Vanheerswynghels, M, De Wolf, C, Van De Velde, E, Hammad, H, Lambrecht, BN, Eyckerman, S, Janssens, S. IRE1beta does not affect mucus secretion during allergic asthma development in a house dust mite murine model Allergy 76, 3546-3549, 2021. (Epub 2021 Aug 12)
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Cloots, E, Simpson, MS, De Nolf, C, Lencer, WI, Janssens, S, Grey, MJ. Evolution and function of the epithelial cell-specific ER stress sensor IRE1beta Mucosal Immunol 14, 1235–1246, 2021. (Epub 2021 Jun 1)
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Cohen, K, Mouhadeb, O, Ben Shlomo, S, Langer, M, Neumann, A, Erez, N, Moshkovits, I, Pelet, R, Kedar, DJ, Brazowski, E, Guilliams, M, Goodridge, HS, Gluck, N, Varol, C. COMMD10 is critical for Kupffer cell survival and controls Ly6C(hi) monocyte differentiation and inflammation in the injured liver Cell Rep 37, 110026, 2021. (Epub 2021 Nov 16)
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Coornaert, I, Puylaert, P, Marcasolli, G, Grootaert, MOJ, Vandenabeele, P, De Meyer, GRY, Martinet, W. Impact of myeloid RIPK1 gene deletion on atherogenesis in ApoE-deficient mice Atherosclerosis 322, 51-60, 2021. (Epub 2021 Feb 24)
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Costantino, F, Aegerter, P, Schett, G, De Craemer, AS, Molto, A, Van den Bosch, F, Elewaut, D, Breban, M, D'Agostino, MA. Cluster analysis in early axial spondyloarthritis predicts poor outcome in the presence of peripheral articular manifestations Rheumatology (Oxford) , in press, 2021. (Epub 2021 Dec 3)
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Decaesteker, B, Durinck, K, Van Roy, N, De Wilde, B, Van Neste, C, Van Haver, S, Roberts, S, De Preter, K, Vermeirssen, V, Speleman, F. From DNA Copy Number Gains and Tumor Dependencies to Novel Therapeutic Targets for High-Risk Neuroblastoma J Pers Med 11, 1286, 2021. (Epub 2021 Dec 3)
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Deckers, J, Marsland, BJ, von Mutius, E. Protection against allergies: Microbes, immunity, and the farming effect Eur J Immunol 51, 2387-2398, 2021. (Epub 2021 Sep 6)
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Declercq, J, Van Damme, KFA, De Leeuw, E, Maes, B, Bosteels, C, Tavernier, SJ, De Buyser, S, Colman, R, Hites, M, Verschelden, G, Fivez, T, Moerman, F, Demedts, IK, Dauby, N, De Schryver, N, Govaerts, E, Vandecasteele, SJ, Van Laethem, J, Anguille, S, et al.. Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID): a factorial, randomised, controlled trial Lancet Respir Med 9, 1427-1438, 2021. (Epub 2021 Oct 29)
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Deconinck, L, Cannoodt, R, Saelens, W, Deplancke, B, Saeys, Y. Recent advances in trajectory inference from single-cell omics data Current Opinion in Systems Biology 27, 100344, 2021. (Epub 2021 Sep)
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De Craemer, AS, Renson, T, Deroo, L, Van Praet, L, Cypers, H, Varkas, G, Joos, R, Devinck, M, Gyselbrecht, L, Peene, I, Thevissen, K, Costantino, F, D'Agostino, MA, Lenaerts, J, Carron, P, Van den Bosch, F, Elewaut, D. Peripheral manifestations are major determinants of disease phenotype and outcome in new onset spondyloarthritis Rheumatology (Oxford) , in press, 2021. (Epub 2021 Nov 30)
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De Galan, C, De Vos, M, Hindryckx, P, Laukens, D, Van Welden, S. Long-Term Environmental Hypoxia Exposure and Haematopoietic Prolyl Hydroxylase-1 Deletion Do Not Impact Experimental Crohn's Like Ileitis Biology (Basel) 10, 887, 2021. (Epub 2021 Sep 8)
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Delaney, C, Farrell, M, Doherty, CP, Brennan, K, O'Keeffe, E, Greene, C, Byrne, K, Kelly, E, Birmingham, N, Hickey, P, Cronin, S, Savvides, SN, Doyle, SL, Campbell, M. Attenuated CSF-1R signalling drives cerebrovascular pathology EMBO Mol Med 13, e12889, 2021. (Epub 2020 Dec 22)
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Delanghe, T, Huyghe, J, Lee, S, Priem, D, Van Coillie, S, Gilbert, B, Choi, SM, Vandenabeele, P, Degterev, A, Cuny, GD, Dondelinger, Y, Bertrand, MJM. Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor Cell Death Dis 12, 699, 2021. (Epub 2021 Jul 14)
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De Mits, S, De Craemer, AS, Deroo, L, Renson, T, Van den Bosch, FE, Carron, P, Elewaut, D. Unexpected impact of COVID-19 lockdown on spinal mobility and health perception in spondyloarthritis Ann Rheum Dis 80, 1638-1640, 2021. (Epub 2021 Jun 29)
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De Munck, S, Provost, M, Kurikawa, M, Omori, I, Mukohyama, J, Felix, J, Bloch, Y, Abdel-Wahab, O, Bazan, JF, Yoshimi, A, Savvides, SN. Structural basis of cytokine-mediated activation of ALK family receptors Nature 600, 143-147, 2021. (Epub 2021 Oct 13)
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De Ponti, FF, Scott, CL. In matters of the heart, (cellular) communication is key Immunity 54, 1906-1908, 2021. (Epub 2021 Sep 14)
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de Reuver, R, Dierick, E, Wiernicki, B, Staes, K, Seys, L, De Meester, E, Muyldermans, T, Botzki, A, Lambrecht, BN, Van Nieuwerburgh, F, Vandenabeele, P, Maelfait, J. ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation Cell Rep 36, 109500, 2021. (Epub 2021 Aug 10)
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De Schutter, E, Cappe, B, Wiernicki, B, Vandenabeele, P, Riquet, FB. Plasma membrane permeabilization following cell death: many ways to dye! Cell Death Discov 7, 183, 2021. (Epub 2021 Jul 19)
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De Schutter, E, Croes, L, Ibrahim, J, Pauwels, P, Op de Beeck, K, Vandenabeele, P, Van Camp, G. GSDME and its role in cancer: From behind the scenes to the front of the stage Int J Cancer 148, 2872-2883, 2021. (Epub 2020 Nov 13)
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De Schutter, E, Roelandt, R, Riquet, FB, Van Camp, G, Wullaert, A, Vandenabeele, P. Punching Holes in Cellular Membranes: Biology and Evolution of Gasdermins Trends Cell Biol 31, 500-513, 2021. (Epub 2021 Mar 23)
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Desmet, S, Saeys, Y, Verstaen, K, Dauwe, R, Kim, H, Niculaes, C, Fukushima, A, Goeminne, G, Vanholme, R, Ralph, J, Boerjan, W, Morreel, K. Maize specialized metabolome networks reveal organ-preferential mixed glycosides Comput Struct Biotechnol J 19, 1127-1144, 2021. (Epub 2021 jan 26)
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De Spiegeleer, A, Kahya, H, Sanchez-Rodriguez, D, Piotrowicz, K, Surquin, M, Marco, E, Detremerie, C, Hussein, D, Hope, S, Dallmeier, D, Decker, G, Hrnciarikova, D, Czesak, J, Toscano-Rico, M, Meza-Valderrama, D, Bahat, G, Descamps, A, Wynendaele, E, Elewaut, D, et al.. Acute sarcopenia changes following hospitalization: influence of pre-admission care dependency level Age Ageing 50, 2140-2146, 2021. (Epub 2021 Aug 9)
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De Vlaminck, K, Romao, E, Puttemans, J, Pombo Antunes, AR, Kancheva, D, Scheyltjens, I, Van Ginderachter, JA, Muyldermans, S, Devoogdt, N, Movahedi, K, Raes, G. Imaging of Glioblastoma Tumor-Associated Myeloid Cells Using Nanobodies Targeting Signal Regulatory Protein Alpha Front Immunol 12, 777524, 2021. (Epub 2021 Nov 30)
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de Vlam, K, Steinfeld, S, Toukap, AN, van den Bosch, F, Joos, R, Geussens, P, Leroi, H, Lories, R, Investigators, BS. The burden of psoriatic arthritis in the biological era: data from the Belgian Epidemiological Psoriatic Arthritis Study (BEPAS) Rheumatology (Oxford) 60, 5677-5685, 2021. (Epub 2021 Mar 12)
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De Vrieze, J, Baptista, AP, Nuhn, L, Van Herck, S, Deswarte, K, Yu, HJ, Lambrecht, BN, De Geest, BG. Lipid Nature and Alkyl Length Influence Lymph Node Accumulation of Lipid-Polyethylene Glycol Amphiphiles Advanced Therapeutics 4, 2100079, 2021. (Epub 2021 Jul 26)
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Dhont, S, Derom, E, Van Braeckel, E, Depuydt, P, Lambrecht, BN. Conceptions of the pathophysiology of happy hypoxemia in COVID-19 Respir Res 22, 12, 2021. (Epub 2021 Jan 8)
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D'Huyvetter, M, De Vos, J, Caveliers, V, Vaneycken, I, Heemskerk, J, Duhoux, FP, Fontaine, C, Vanhoeij, M, Windhorst, AD, van der Aa, F, Hendrikse, NH, Eersels, JLE, Everaert, H, Gykiere, P, Devoogdt, N, Raes, G, Lahoutte, T, Keyaerts, M. Phase I trial of (131)I-GMIB-Anti-HER2-VHH1, a new promising candidate for HER2-targeted radionuclide therapy in breast cancer patients J Nucl Med 62, 1097-1105, 2021. (Epub 2020 Dec 4)
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Di Grande, A, Peirs, S, Donovan, PD, Van Trimpont, M, Morscio, J, Lintermans, B, Reunes, L, Vandamme, N, Goossens, S, Nguyen, HA, Lavie, A, Lock, RB, Prehn, JHM, Van Vlierberghe, P, Ni Chonghaile, T. The spleen as a sanctuary site for residual leukemic cells following ABT-199 monotherapy in ETP-ALL Blood Adv 5, 1963-1976, 2021. (Epub 2021 Apr 13)
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Duetz, C, Van Gassen, S, Westers, TM, van Spronsen, MF, Bachas, C, Saeys, Y, van de Loosdrecht, AA. Computational flow cytometry as a diagnostic tool in suspected-myelodysplastic syndromes Cytometry A 99, 814-824, 2021. (Epub 2021 May 3)
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Elewaut, D, Braun, J, Anderson, JK, Arikan, D, Chen, S, Hojnik, M, De Craemer, AS, Curtis, JR. Low Incidence of Inflammatory Bowel Disease Adverse Events in Adalimumab Clinical Trials Across Nine Different Diseases Arthritis Care Res (Hoboken) 73, 289–295, 2021. (Epub 2020 Feb 26)
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El Kharraz, S, Dubois, V, van Royen, ME, Houtsmuller, AB, Pavlova, E, Atanassova, N, Nguyen, T, Voet, A, Eerlings, R, Handle, F, Prekovic, S, Smeets, E, Moris, L, Devlies, W, Ohlsson, C, Poutanen, M, Verstrepen, KJ, Carmeliet, G, Launonen, KM, et al.. The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation EMBO Rep , e52764, 2021. (Epub 2021 Oct 18)
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Fleischmann, RM, Blanco, R, Hall, S, Thomson, GTD, Van den Bosch, FE, Zerbini, C, Bessette, L, Enejosa, J, Li, Y, Song, Y, DeMasi, R, Song, IH. Switching between Janus kinase inhibitor upadacitinib and adalimumab following insufficient response: efficacy and safety in patients with rheumatoid arthritis Ann Rheum Dis 80, 432-439, 2021. (Epub 2020 Nov 4)
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Geeraerts, X, Fernandez-Garcia, J, Hartmann, FJ, de Goede, KE, Martens, L, Elkrim, Y, Debraekeleer, A, Stijlemans, B, Vandekeere, A, Rinaldi, G, De Rycke, R, Planque, M, Broekaert, D, Meinster, E, Clappaert, E, Bardet, P, Murgaski, A, Gysemans, C, Nana, FA, et al.. Macrophages are metabolically heterogeneous within the tumor microenvironment Cell Rep 37, 110171, 2021. (Epub 2021 Dec 28)
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Geisberger, S, Bartolomaeus, H, Neubert, P, Willebrand, R, Zasada, C, Bartolomaeus, T, McParland, V, Swinnen, D, Geuzens, A, Maifeld, A, Krampert, L, Vogl, M, Mahler, A, Wilck, N, Marko, L, Tilic, E, Forslund, SK, Binger, KJ, Stegbauer, J, et al.. Salt Transiently Inhibits Mitochondrial Energetics in Mononuclear Phagocytes Circulation 144, 144-158, 2021. (Epub 2021 Apr 28)
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Germanova, D, Keirsse, J, Kohler, A, Hastir, JF, Demetter, P, Delbauve, S, Elkrim, Y, Verset, L, Larbanoix, L, Preyat, N, Laurent, S, Nedospasov, S, Donckier, V, Van Ginderachter, JA, Flamand, V. Myeloid TNF and HO-1 regulate the progression of colorectal liver metastases during hepatic ischemia-reperfusion Int J Cancer 148, 1276–1288, 2021. (Epub 2020 Oct 10)
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Gola, A, Dorrington, MG, Speranza, E, Sala, C, Shih, RM, Radtke, AJ, Wong, HS, Baptista, AP, Hernandez, JM, Castellani, G, Fraser, IDC, Germain, RN. Commensal-driven immune zonation of the liver promotes host defence Nature 589, 131-136, 2021. (Epub 2020 Nov 25)
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Gorle, N, Bauwens, E, Haesebrouck, F, Smet, A, Vandenbroucke, RE. Helicobacter and the Potential Role in Neurological Disorders: There Is More Than Helicobacter pylori Front Immunol 11, 584165, 2021. (Epub 2021 Jan 28)
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Grigoryan, R, Costas-Rodriguez, M, Van Wonterghem, E, Vandenbroucke, RE, Vanhaecke, F. Effect of Endotoxemia Induced by Intraperitoneal Injection of Lipopolysaccharide on the Mg isotopic Composition of Biofluids and Tissues in Mice Front Med (Lausanne) 8, 664666, 2021. (Epub 2021 Jul 23)
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Guerin, CJ, Lippens, S. Correlative light and volume electron microscopy (vCLEM): How community participation can advance developing technologies J Microsc 284, 97-102, 2021. (Epub 2021 Sep 20)
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Guggino, G, Mauro, D, Rizzo, A, Alessandro, R, Raimondo, S, Bergot, AS, Rahman, MA, Ellis, JJ, Milling, S, Lories, R, Elewaut, D, Brown, MA, Thomas, R, Ciccia, F. Inflammasome activation in Ankylosing Spondylitis is associated to gut dysbiosis Arthritis Rheumatol 73, 1189-1199, 2021. (Epub 2021 Jan 16)
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Guilliams, M, Scott, CL. The conventional dendritic cell lineage is born Nat Rev Immunol 21, 623, 2021. (Epub 2021 Sep 27)
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Guilliams, M, Svedberg, FR. Does tissue imprinting restrict macrophage plasticity? Nat Immunol 22, 118-127, 2021. (Epub 2021 Jan 18)
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Gupta, D, Wiklander, OPB, Gorgens, A, Conceicao, M, Corso, G, Liang, X, Seow, Y, Balusu, S, Feldin, U, Bostancioglu, B, Jawad, R, Mamand, DR, Lee, YXF, Hean, J, Mager, I, Roberts, TC, Gustafsson, M, Mohammad, DK, Sork, H, et al.. Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles Nat Biomed Eng 5, 1084-1098, 2021. (Epub 2021 Oct 6)
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Gurumurthy, CB, O'Brien, AR, Quadros, RM, Adams, J, Jr., Alcaide, P, Ayabe, S, Ballard, J, Batra, SK, Beauchamp, MC, Becker, KA, Bernas, G, Brough, D, Carrillo-Salinas, F, Chan, W, Chen, H, Dawson, R, DeMambro, V, D'Hont, J, Dibb, K, et al.. Response to correspondence on "Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation" Genome Biol 22, 99, 2021. (Epub 2021 Apr 7)
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