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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Ackaert, C, Smiejkowska, N, Xavier, C, Sterckx, YGJ, Denies, S, Stijlemans, B, Elkrim, Y, Devoogdt, N, Caveliers, V, Lahoutte, T, Muyldermans, S, Breckpot, K, Keyaerts, M. Immunogenicity Risk Profile of Nanobodies Front Immunol 12, 632687, 2021. (Epub 2021 Mar 9) 
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Ackermann, M, Anders, HJ, Bilyy, R, Bowlin, GL, Daniel, C, De Lorenzo, R, Egeblad, M, Henneck, T, Hidalgo, A, Hoffmann, M, Hohberger, B, Kanthi, Y, Kaplan, MJ, Knight, JS, Knopf, J, Kolaczkowska, E, Kubes, P, Leppkes, M, Mahajan, A, et al.. Patients with COVID-19: in the dark-NETs of neutrophils Cell Death Differ 28, 3125-3139, 2021. (Epub 2021 May 24)
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Adami, V, Homer, N, Utz, N, Lippens, S, Rappoport, JZ, Fernandez-Rodriguez, J. An international survey of Training Needs and Career Paths of Core Facility Staff J Biomol Tech 32, 1-9, 2021. (Epub 2020 Nov 20)
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Aegerter, H, Smole, U, Heyndrickx, I, Verstraete, K, Savvides, SN, Hammad, H, Lambrecht, BN. Charcot-Leyden crystals and other protein crystals driving type 2 immunity and allergy Curr Opin Immunol 72, 104-110, 2021. (Epub 2021 Apr 16)
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Afonina, IS, Van Nuffel, E, Beyaert, R. Immune responses and therapeutic options in psoriasis Cell Mol Life Sci 78, 2709–2727, 2021. (Epub 2021 Jan 2)
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Aguilera-Lizarraga, J, Florens, MV, Viola, MF, Jain, P, Decraecker, L, Appeltans, I, Cuende-Estevez, M, Fabre, N, Van Beek, K, Perna, E, Balemans, D, Stakenborg, N, Theofanous, S, Bosmans, G, Mondelaers, SU, Matteoli, G, Ibiza Martinez, S, Lopez-Lopez, C, Jaramillo-Polanco, J, et al.. Local immune response to food antigens drives meal-induced abdominal pain Nature 590, 151-156, 2021. (Epub 2021 Jan 13)
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Alexander, SP, Fabbro, D, Kelly, E, Mathie, A, Peters, JA, Veale, EL, Armstrong, JF, Faccenda, E, Harding, SD, Pawson, AJ, Southan, C, Davies, JA, Beuve, A, Brouckaert, P, Bryant, C, Burnett, JC, Farndale, RW, Friebe, A, Garthwaite, J, et al.. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors Br J Pharmacol 178, S264-S312, 2021. (Epub 2021 Sep 17)
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Almeida, L, Dhillon-LaBrooy, A, Castro, CN, Adossa, N, Carriche, GM, Guderian, M, Lippens, S, Dennerlein, S, Hesse, C, Lambrecht, BN, Berod, L, Schauser, L, Blazar, BR, Kalesse, M, Muller, R, Moita, LF, Sparwasser, T. Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis Immunity 54, 68-83, 2021. (Epub 2020 Nov 24)
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Anderson, CJ, Medina, CB, Barron, BJ, Karvelyte, L, Aaes, TL, Lambertz, I, Perry, JSA, Mehrotra, P, Goncalves, A, Lemeire, K, Blancke, G, Andries, V, Ghazavi, F, Martens, A, van Loo, G, Vereecke, L, Vandenabeele, P, Ravichandran, KS. Microbes exploit death-induced nutrient release by gut epithelial cells Nature 596, 262-267, 2021. (Epub 2021 Aug 4)
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Andries, L, Masin, L, Navarro, MS, Zaunz, S, Claes, M, Bergmans, S, Brouwers, V, Lefevere, E, Verfaillie, C, Movahedi, K, De Groef, L, Moons, L. MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System Cells 10, 1672, 2021. (Epub 2021 Jul 2)
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Arandjelovic, S, Perry, JSA, Zhou, M, Ceroi, A, Smirnov, I, Walk, SF, Shankman, LS, Cambre, I, Onengut-Gumuscu, S, Elewaut, D, Conrads, TP, Ravichandran, KS. ELMO1 signaling is a promoter of osteoclast function and bone loss Nat Commun 12, 4974, 2021. (Epub 2021 Aug 17)
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Awad, RM, Lecocq, Q, Zeven, K, Ertveldt, T, De Beck, L, Ceuppens, H, Broos, K, De Vlaeminck, Y, Goyvaerts, C, Verdonck, M, Raes, G, Van Parys, A, Cauwels, A, Keyaerts, M, Devoogdt, N, Breckpot, K. Formatting and gene-based delivery of a human PD-L1 single domain antibody for immune checkpoint blockade Mol Ther Methods Clin Dev 22, 172-182, 2021. (Epub 2021 Sep 10)
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Backers, L, Parton, B, De Bruyne, M, Tavernier, SJ, Van Den Bogaert, K, Lambrecht, BN, Haerynck, F, Claes, KBM. Missing heritability in Bloom syndrome: First report of a deep intronic variant leading to pseudo-exon activation in the BLM gene Clin Genet 99, 292-297, 2021. (Epub 2020 Oct 9)
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Baldan, FJ, Peralta, D, Saeys, Y, Benitez, JM. SCMFTS: Scalable and Distributed Complexity Measures and Features for Univariate and Multivariate Time Series in Big Data Environments International Journal of Computational Intelligence Systems 14, 186, 2021. (Epub 2021 Nov 2)
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Baptista, AP, Gerner, MY. Lymphoid stromal cells proGrem dendritic cell homeostasis Nat Immunol 22, 541-543, 2021. (Epub 2021 Apr 26)
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Baraliakos, X, Van den Bosch, F, Machado, PM, Gensler, LS, Marzo-Ortega, H, Sherif, B, Quebe-Fehling, E, Porter, B, Gaillez, C, Deodhar, A. Achievement of Remission Endpoints with Secukinumab Over 3 Years in Active Ankylosing Spondylitis: Pooled Analysis of Two Phase 3 Studies Rheumatol Ther 8, 273-288, 2021. (Epub 2020 Dec 22)
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Barca, C, Foray, C, Hermann, S, Herrlinger, U, Remory, I, Laoui, D, Schafers, M, Grauer, OM, Zinnhardt, B, Jacobs, AH. The Colony Stimulating Factor-1 Receptor (CSF-1R)-Mediated Regulation of Microglia/Macrophages as a Target for Neurological Disorders (Glioma, Stroke) Front Immunol 12, 787307, 2021. (Epub 2021 Dec 7)
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Baudhuin, H, Cousaert, J, Vanwolleghem, P, Raes, G, Caveliers, V, Keyaerts, M, Lahoutte, T, Xavier, C. (68)Ga-Labeling: Laying the Foundation for an Anti-Radiolytic Formulation for NOTA-sdAb PET Tracers Pharmaceuticals (Basel) 14, 448, 2021. (Epub 2021 May 10)
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Baudhuin, H, Puttemans, J, Hanssens, H, Vanwolleghem, P, Hernot, S, Raes, G, Xavier, C, Lahoutte, T, Debie, P. Decorating sdAbs with Chelators: Effect of Conjugation on Biodistribution and Functionality Pharmaceuticals (Basel) 14, 407, 2021. (Epub 2021 Apr 25)
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Baudhuin, H, Van Bockstal, PJ, De Beer, T, Vaneycken, I, Bridoux, J, Raes, G, Caveliers, V, Keyaerts, M, Devoogdt, N, Lahoutte, T, Xavier, C. Lyophilization of NOTA-sdAbs: first step towards a cold diagnostic kit for (68)Ga-labeling Eur J Pharm Biopharm 166, 194-204, 2021. (Epub 2021 Jun 26)
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Behrens, F, Leage, SL, Sapin, C, Baou, CE, De La Torre, I, Meszaros, G, Schett, G, Combe, B, van den Bosch, F, Gossec, L. Measuring treatment effect on psoriatic arthritis-related domains: insights from the SPIRIT-H2H study at weeks 24 and 52 Clin Rheumatol 40, 4943-4954, 2021. (Epub 2021 Sep 13)
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Berlamont, H, Bruggeman, A, Bauwens, E, Vandendriessche, C, Clarebout, E, Xie, J, De Bruyckere, S, Van Imschoot, G, Van Wonterghem, E, Ducatelle, R, Santens, P, Smet, A, Haesebrouck, F, Vandenbroucke, RE. Gastric Helicobacter suis Infection Partially Protects against Neurotoxicity in A 6-OHDA Parkinson's Disease Mouse Model Int J Mol Sci 22, 11328, 2021. (Epub 2021 Oct 20)
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Bolli, E, Scherger, M, Arnouk, SM, Pombo Antunes, AR, Strassburger, D, Urschbach, M, Stickdorn, J, De Vlaminck, K, Movahedi, K, Rader, HJ, Hernot, S, Besenius, P, Van Ginderachter, JA, Nuhn, L. Targeted Repolarization of Tumor-Associated Macrophages via Imidazoquinoline-Linked Nanobodies Adv Sci (Weinh) 8, 2004574, 2021. (Epub 2021 Mar 8)
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Borras-Tuduri, R, Alcaide, A, Aspeslag, S, Usero, L, Serra, C, Roura-Mir, C, Elewaut, D, Llebaria, A. New paradigm in NKT cell antigens: MCS-0208 (2-(Hydroxymethyl)phenylthio-phytoceramide) an aryl-phytoceramide compound with a single hydroxyl group stimulates NKT cells ChemMedChem 16, 2491-2496, 2021. (Epub 2021 Apr 6)
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Bosteels, C, Fierens, K, De Prijck, S, Van Moorleghem, J, Vanheerswynghels, M, De Wolf, C, Chalon, A, Collignon, C, Hammad, H, Didierlaurent, AM, Lambrecht, BN. CCR2- and Flt3-Dependent Inflammatory Conventional Type 2 Dendritic Cells Are Necessary for the Induction of Adaptive Immunity by the Human Vaccine Adjuvant System AS01 Front Immunol 11, 606805, 2021. (Epub 2021 Jan 14)
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Braun, J, Blanco, R, Marzo-Ortega, H, Gensler, LS, van den Bosch, F, Hall, S, Kameda, H, Poddubnyy, D, van de Sande, M, Wiksten, AS, Porter, BO, Shete, A, Richards, HB, Haemmerle, S, Deodhar, A. Secukinumab in non-radiographic axial spondyloarthritis: subgroup analysis based on key baseline characteristics from a randomized phase III study, PREVENT Arthritis Res Ther 23, 231, 2021. (Epub 2021 Sep 4)
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Brightling, C, Kulkarni, S, Lambrecht, BN, Sandham, D, Weiss, M, Altman, P. The pharmacology of the prostaglandin D2 receptor 2 (DP2) receptor antagonist, fevipiprant Pulm Pharmacol Ther 68, 102030, 2021. (Epub 2021 Apr 4)
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Burgelman, M, Vandendriessche, C, Vandenbroucke, RE. Extracellular Vesicles: A Double-Edged Sword in Sepsis Pharmaceuticals (Basel) 14, 829, 2021. (Epub 2021 Aug 23)
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Cable, J, Elowitz, MB, Domingos, AI, Habib, N, Itzkovitz, S, Hamidzada, H, Balzer, MS, Yanai, I, Liberali, P, Whited, J, Streets, A, Cai, L, Stergachis, AB, Hong, CKY, Keren, L, Guilliams, M, Alon, U, Shalek, AK, Hamel, R, et al.. Single cell biology-a Keystone Symposia report Ann N Y Acad Sci 1506, 74-97, 2021. (Epub 2021 Oct 3)
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Cannoodt, R, Saelens, W, Deconinck, L, Saeys, Y. Spearheading future omics analyses using dyngen, a multi-modal simulator of single cells Nat Commun 12, 3942, 2021. (Epub 2021 Jun 24)
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Canti, L, Chrzanowska, A, Doglio, MG, Martina, L, Van Den Bossche, T. Research culture: science from bench to society Biol Open 10, bio058919, 2021. (Epub 2021 Aug 15)
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Carbo, JM, Leon, TE, Font-Diaz, J, De la Rosa, JV, Castrillo, A, Picard, FR, Staudenraus, D, Huber, M, Cedo, L, Escola-Gil, JC, Campos, L, Bakiri, L, Wagner, EF, Caelles, C, Stratmann, T, Van Ginderachter, JA, Valledor, AF. Pharmacological activation of LXR alters the expression profile of tumor-associated macrophages and the abundance of regulatory T cells in the tumor microenvironment Cancer Res 81, 968-985, 2021. (Epub 2020 Dec 23)
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Carron, P, De Craemer, AS, Renson, T, Colman, R, Elewaut, D, Van den Bosch, F. TNFi-induced sustained clinical remission in peripheral spondyloarthritis patients cannot be maintained with a step-down strategy based on methotrexate Rheumatology (Oxford) 60, 4880-4883, 2021. (Epub 2021 Oct 21)
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Catrysse, L, Maes, B, Mehrotra, P, Martens, A, Hoste, E, Martens, L, Maueroder, C, Remmerie, A, Bujko, A, Slowicka, K, Sze, M, Vikkula, H, Ghesquiere, B, Scott, CL, Saeys, Y, van de Sluis, B, Ravichandran, K, Janssens, S, van Loo, G. A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism Cell Rep 36, 109748, 2021. (Epub 2021 Sep 21)
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Claeys, W, Van Hoecke, L, Lefere, S, Geerts, A, Verhelst, X, Van Vlierberghe, H, Degroote, H, Devisscher, L, Vandenbroucke, RE, Van Steenkiste, C. The neurogliovascular unit in hepatic encephalopathy JHEP Rep 3, 100352, 2021. (Epub 2021 Aug 11 )
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Cloots, E, Debeuf, N, Deswarte, K, Fayazpour, F, Vanheerswynghels, M, De Wolf, C, Van De Velde, E, Hammad, H, Lambrecht, BN, Eyckerman, S, Janssens, S. IRE1beta does not affect mucus secretion during allergic asthma development in a house dust mite murine model Allergy 76, 3546-3549, 2021. (Epub 2021 Aug 12)
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Cloots, E, Simpson, MS, De Nolf, C, Lencer, WI, Janssens, S, Grey, MJ. Evolution and function of the epithelial cell-specific ER stress sensor IRE1beta Mucosal Immunol 14, 1235–1246, 2021. (Epub 2021 Jun 1)
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Cohen, K, Mouhadeb, O, Ben Shlomo, S, Langer, M, Neumann, A, Erez, N, Moshkovits, I, Pelet, R, Kedar, DJ, Brazowski, E, Guilliams, M, Goodridge, HS, Gluck, N, Varol, C. COMMD10 is critical for Kupffer cell survival and controls Ly6C(hi) monocyte differentiation and inflammation in the injured liver Cell Rep 37, 110026, 2021. (Epub 2021 Nov 16)
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Coornaert, I, Puylaert, P, Marcasolli, G, Grootaert, MOJ, Vandenabeele, P, De Meyer, GRY, Martinet, W. Impact of myeloid RIPK1 gene deletion on atherogenesis in ApoE-deficient mice Atherosclerosis 322, 51-60, 2021. (Epub 2021 Feb 24)
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Decaesteker, B, Durinck, K, Van Roy, N, De Wilde, B, Van Neste, C, Van Haver, S, Roberts, S, De Preter, K, Vermeirssen, V, Speleman, F. From DNA Copy Number Gains and Tumor Dependencies to Novel Therapeutic Targets for High-Risk Neuroblastoma J Pers Med 11, 1286, 2021. (Epub 2021 Dec 3)
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Deckers, J, Marsland, BJ, von Mutius, E. Protection against allergies: Microbes, immunity, and the farming effect Eur J Immunol 51, 2387-2398, 2021. (Epub 2021 Sep 6)
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Declercq, J, Van Damme, KFA, De Leeuw, E, Maes, B, Bosteels, C, Tavernier, SJ, De Buyser, S, Colman, R, Hites, M, Verschelden, G, Fivez, T, Moerman, F, Demedts, IK, Dauby, N, De Schryver, N, Govaerts, E, Vandecasteele, SJ, Van Laethem, J, Anguille, S, et al.. Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID): a factorial, randomised, controlled trial Lancet Respir Med 9, 1427-1438, 2021. (Epub 2021 Oct 29)
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Deconinck, L, Cannoodt, R, Saelens, W, Deplancke, B, Saeys, Y. Recent advances in trajectory inference from single-cell omics data Current Opinion in Systems Biology 27, 100344, 2021. (Epub 2021 Sep)
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De Galan, C, De Vos, M, Hindryckx, P, Laukens, D, Van Welden, S. Long-Term Environmental Hypoxia Exposure and Haematopoietic Prolyl Hydroxylase-1 Deletion Do Not Impact Experimental Crohn's Like Ileitis Biology (Basel) 10, 887, 2021. (Epub 2021 Sep 8)
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Delaney, C, Farrell, M, Doherty, CP, Brennan, K, O'Keeffe, E, Greene, C, Byrne, K, Kelly, E, Birmingham, N, Hickey, P, Cronin, S, Savvides, SN, Doyle, SL, Campbell, M. Attenuated CSF-1R signalling drives cerebrovascular pathology EMBO Mol Med 13, e12889, 2021. (Epub 2020 Dec 22)
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Delanghe, T, Huyghe, J, Lee, S, Priem, D, Van Coillie, S, Gilbert, B, Choi, SM, Vandenabeele, P, Degterev, A, Cuny, GD, Dondelinger, Y, Bertrand, MJM. Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor Cell Death Dis 12, 699, 2021. (Epub 2021 Jul 14)
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De Mits, S, De Craemer, AS, Deroo, L, Renson, T, Van den Bosch, FE, Carron, P, Elewaut, D. Unexpected impact of COVID-19 lockdown on spinal mobility and health perception in spondyloarthritis Ann Rheum Dis 80, 1638-1640, 2021. (Epub 2021 Jun 29)
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De Munck, S, Provost, M, Kurikawa, M, Omori, I, Mukohyama, J, Felix, J, Bloch, Y, Abdel-Wahab, O, Bazan, JF, Yoshimi, A, Savvides, SN. Structural basis of cytokine-mediated activation of ALK family receptors Nature 600, 143-147, 2021. (Epub 2021 Oct 13)
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De Ponti, FF, Scott, CL. In matters of the heart, (cellular) communication is key Immunity 54, 1906-1908, 2021. (Epub 2021 Sep 14)
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de Reuver, R, Dierick, E, Wiernicki, B, Staes, K, Seys, L, De Meester, E, Muyldermans, T, Botzki, A, Lambrecht, BN, Van Nieuwerburgh, F, Vandenabeele, P, Maelfait, J. ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation Cell Rep 36, 109500, 2021. (Epub 2021 Aug 10)
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