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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Yperman, K, Papageorgiou, AC, Merceron, R, De Munck, S, Bloch, Y, Eeckhout, D, Jiang, Q, Tack, P, Grigoryan, R, Evangelidis, T, Van Leene, J, Vincze, L, Vandenabeele, P, Vanhaecke, F, Potocky, M, De Jaeger, G, Savvides, SN, Tripsianes, K, Pleskot, R, et al.. Distinct EH domains of the endocytic TPLATE complex confer lipid and protein binding Nat Commun 12, 3050, 2021. (Epub 2021 May 24) 
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Yperman, K, Wang, J, Eeckhout, D, Winkler, J, Vu, LD, Vandorpe, M, Grones, P, Mylle, E, Kraus, M, Merceron, R, Nolf, J, Mor, E, De Bruyn, P, Loris, R, Potocky, M, Savvides, SN, De Rybel, B, De Jaeger, G, Van Damme, D, et al.. Molecular architecture of the endocytic TPLATE complex Sci Adv 7, eabe7999, 2021. (Epub 2021 Feb 26)
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Zheng, F, Zhou, J, Ouyang, Z, Zhang, J, Wang, X, Muyldermans, S, Van Ginderachter, J, Devoogdt, N, Wen, Y, Schoonooghe, S, Raes, G. Development and Characterization of Nanobodies Targeting the Kupffer Cell Front Immunol 12, 641819, 2021. (Epub 2021 Feb 22)
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Zwicker, C, Bujko, A, Scott, CL. Hepatic Macrophage Responses in Inflammation, a Function of Plasticity, Heterogeneity or Both? Front Immunol 12, 690813, 2021. (Epub 2021 Jun 9)
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Aaes, TL, Vandenabeele, P. The intrinsic immunogenic properties of cancer cell lines, immunogenic cell death, and how these influence host antitumor immune responses Cell Death Differ 28, 843-860, 2020. (Epub 2020 Nov 19)
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Aaes, TL, Verschuere, H, Kaczmarek, A, Heyndrickx, L, Wiernicki, B, Delrue, I, De Craene, B, Taminau, J, Delvaeye, T, Bertrand, MJM, Declercq, W, Berx, G, Krysko, DV, Adjemian, S, Vandenabeele, P. Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection J Immunol 204, 775-787, 2020. (Epub 2020 Jan 3)
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Adjemian, S, Oltean, T, Martens, S, Wiernicki, B, Goossens, V, Vanden Berghe, T, Cappe, B, Ladik, M, Riquet, FB, Heyndrickx, L, Bridelance, J, Vuylsteke, M, Vandecasteele, K, Vandenabeele, P. Ionizing radiation results in a mixture of cellular outcomes including mitotic catastrophe, senescence, methuosis, and iron-dependent cell death Cell Death Dis 11, 1003, 2020. (Epub 2020 Nov 23)
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Aouad, K, De Craemer, AS, Carron, P. Can Imaging Be a Proxy for Remission in Axial Spondyloarthritis? Rheum Dis Clin North Am 46, 311-325, 2020. (Epub May 2020)
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Arroyo Hornero, R, Hamad, I, Corte-Real, B, Kleinewietfeld, M. The Impact of Dietary Components on Regulatory T Cells and Disease Front Immunol 11, 253, 2020. (Epub 2020 Apr 21)
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Ascari, G, Peelman, F, Farinelli, P, Rosseel, T, Lambrechts, N, Wunderlich, KA, Wagner, M, Nikopoulos, K, Martens, P, Balikova, I, Derycke, L, Holtappels, G, Krysko, O, Van Laethem, T, De Jaegere, S, Guillemyn, B, De Rycke, R, De Bleecker, J, Creytens, D, et al.. Functional characterization of the first missense variant in CEP78, a founder allele associated with cone-rod dystrophy, hearing loss, and reduced male fertility Hum Mutat 41, 998-1011, 2020. (Epub 2020 Jan 30)
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Aw, R, De Wachter, C, Laukens, B, De Rycke, R, De Bruyne, M, Bell, D, Callewaert, N, Polizzi, KM. Knockout of RSN1, TVP18 or CSC1-2 causes perturbation of Golgi cisternae in Pichia pastoris Traffic , in press, 2020. (Epub 2020 Dec 2)
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Bachert, C, Marple, B, Schlosser, RJ, Hopkins, C, Schleimer, RP, Lambrecht, BN, Broker, BM, Laidlaw, T, Song, WJ. Adult chronic rhinosinusitis Nat Rev Dis Primers 6, 86, 2020. (Epub 2020 Oct 29)
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Bauwens, M, Storch, S, Weisschuh, N, Ceuterick-de Groote, C, De Rycke, R, Guillemyn, B, De Jaegere, S, Coppieters, F, Van Coster, R, Leroy, BP, De Baere, E. Functional characterization of novel MFSD8 pathogenic variants anticipates neurological involvement in juvenile isolated maculopathy Clin Genet 97, 426-436, 2020. (Epub 2019 Nov 13)
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Beziat, V, Tavernier, SJ, Chen, YH, Ma, CS, Materna, M, Laurence, A, Staal, J, Aschenbrenner, D, Roels, L, Worley, L, Claes, K, Gartner, L, Kohn, LA, De Bruyne, M, Schmitz-Abe, K, Charbonnier, LM, Keles, S, Nammour, J, Vladikine, N, et al.. Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome J Exp Med 217, e20191804, 2020. (Epub 2020 Mar 24)
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Bogaert, DJ, Laureys, G, Naesens, L, Mazure, D, De Bruyne, M, Hsu, AP, Bordon, V, Wouters, E, Tavernier, SJ, Lambrecht, BN, De Baere, E, Haerynck, F, Kerre, T. GATA2 deficiency and haematopoietic stem cell transplantation: challenges for the clinical practitioner Br J Haematol 188, 768-773, 2020. (Epub 2019 Nov 11)
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Bos, S, Laukens, D. Metabolic modulation during intestinal fibrosis J Dig Dis 21, 319-325, 2020. (Epub 2020 May 14)
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Bosteels, C, Maes, B, Van Damme, K, De Leeuw, E, Declercq, J, Delporte, A, Demeyere, B, Vermeersch, S, Vuylsteke, M, Willaert, J, Bolle, L, Vanbiervliet, Y, Decuypere, J, Libeer, F, Vandecasteele, S, Peene, I, Lambrecht, B. Sargramostim to treat patients with acute hypoxic respiratory failure due to COVID-19 (SARPAC): A structured summary of a study protocol for a randomised controlled trial Trials 21, 491, 2020. (Epub 2020 Jun 5)
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Bosteels, C, Neyt, K, Vanheerswynghels, M, van Helden, MJ, Sichien, D, Debeuf, N, De Prijck, S, Bosteels, V, Vandamme, N, Martens, L, Saeys, Y, Louagie, E, Lesage, M, Williams, DL, Tang, SC, Mayer, JU, Ronchese, F, Scott, CL, Hammad, H, et al.. Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection Immunity 52, 1039-1056, 2020. (Epub 2020 May 4)
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Bosteels, C, Scott, CL. Transcriptional regulation of DC fate specification Mol Immunol 121, 38-46, 2020. (Epub 2020 May)
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Braun, H, Staal, J. Stabilization of the TAK1 adaptor proteins TAB2 and TAB3 is critical for optimal NF-kappaB activation FEBS J 287, 3161-3164, 2020. (Epub 2020 Jan 29)
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Bridoux, J, Broos, K, Lecocq, Q, Debie, P, Martin, C, Ballet, S, Raes, G, Neyt, S, Vanhove, C, Breckpot, K, Devoogdt, N, Caveliers, V, Keyaerts, M, Xavier, C. Anti-human PD-L1 Nanobody for Immuno-PET Imaging: Validation of a Conjugation Strategy for Clinical Translation Biomolecules 10, E1388, 2020. (Epub 2020 Sep 29)
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Browaeys, R, Saelens, W, Saeys, Y. NicheNet: modeling intercellular communication by linking ligands to target genes Nat Methods 17, 159-162, 2020. (Epub 2019 Dec 9)
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Bruneel, K, Verstappe, J, Vandamme, N, Berx, G. Intrinsic Balance between ZEB Family Members Is Important for Melanocyte Homeostasis and Melanoma Progression Cancers (Basel) 12, 2248, 2020. (Epub 2020 Aug 11)
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Bugler-Lamb, A, Guilliams, M. Myeloid Cells TREM Down Anti-tumor Responses Cell 182, 796-798, 2020. (Epub 2020 Aug 20)
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Carmichael, CL, Wang, J, Nguyen, T, Kolawole, O, Benyoucef, A, De Maziere, C, Milne, A, Samuel, S, Gillinder, KR, Hediyeh-Zadeh, S, Vo, ANQ, Huang, Y, Knezevic, K, McInnes, WRL, Shields, BJ, Mitchell, H, Ritchie, ME, Lammens, T, Lintermans, B, et al.. The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1 Blood 136, 957-973, 2020. (Epub 2020 May 5)
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Carron, P, De Craemer, AS, Van den Bosch, F. Peripheral spondyloarthritis: a neglected entity-state of the art RMD Open 6, e001136, 2020. (Epub 2020 May)
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Carron, P, Renson, T, de Hooge, M, Lambert, B, De Man, K, Jans, L, Elewaut, D, Van den Bosch, FE. Immunoscintigraphy in axial spondyloarthritis: a new imaging modality for sacroiliac inflammation Ann Rheum Dis 79, 844-846, 2020. (Epub 2020 Feb 26)
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Chen, M, Herregods, N, Jaremko, JL, Carron, P, Elewaut, D, Van den Bosch, F, Jans, L. Bone marrow edema in sacroiliitis: detection with dual-energy CT Eur Radiol 30, 3393-3400, 2020. (Epub 2020 Feb 13)
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Chen, M, Herregods, N, Jaremko, JL, Carron, P, Elewaut, D, Van den Bosch, F, Jans, L. Diagnostic performance for erosion detection in sacroiliac joints on MR T1-weighted images: Comparison between different slice thicknesses Eur J Radiol 133, 109352, 2020. (Epub 2020 Oct 16)
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Choileain, SN, Kleinewietfeld, M, Raddassi, K, Hafler, DA, Ruff, WE, Longbrake, EE. CXCR3+ T cells in multiple sclerosis correlate with reduced diversity of the gut microbiome J Transl Autoimmun 3, 100032, 2020. (Epub 2019 Dec 20)
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D'Anna, F, Van Dyck, L, Xiong, J, Zhao, H, Berrens, RV, Qian, J, Bieniasz-Krzywiec, P, Chandra, V, Schoonjans, L, Matthews, J, De Smedt, J, Minnoye, L, Amorim, R, Khorasanizadeh, S, Yu, Q, Zhao, L, De Borre, M, Savvides, SN, Simon, MC, et al.. DNA methylation repels binding of hypoxia-inducible transcription factors to maintain tumor immunotolerance Genome Biol 21, 182, 2020. (Epub 2020 Jul 27)
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Debunne, N, De Spiegeleer, A, Depuydt, D, Janssens, Y, Descamps, A, Wynendaele, E, De Spiegeleer, B. Influence of Blood Collection Methods and Long-Term Plasma Storage on Quorum-Sensing Peptide Stability ACS Omega 5, 16120-16127, 2020. (Epub 2020 Jun 22)
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Declercq, J, Bosteels, C, Van Damme, K, De Leeuw, E, Maes, B, Vandecauter, A, Vermeersch, S, Delporte, A, Demeyere, B, Vuylsteke, M, Lalla, M, Smart, T, Detalle, L, Bouw, R, Streffer, J, Degeeter, T, Vergotte, M, Guisez, T, Van Braeckel, E, et al.. Zilucoplan in patients with acute hypoxic respiratory failure due to COVID-19 (ZILU-COV): A structured summary of a study protocol for a randomised controlled trial Trials 21, 934, 2020. (Epub 2020 Nov 19)
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de Hooge, M. The Future of Imaging in Axial Spondyloarthritis Rheum Dis Clin North Am 46, 297-309, 2020. (Epub 2020 May)
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Delanghe, T, Dondelinger, Y, Bertrand, MJM. RIPK1 Kinase-Dependent Death: A Symphony of Phosphorylation Events Trends Cell Biol 30, 189-200, 2020. (Epub 2020 Jan 17)
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Delbaere, S, Dhooge, T, Syx, D, Petit, F, Goemans, N, Destree, A, Vanakker, O, De Rycke, R, Symoens, S, Malfait, F. Novel defects in collagen XII and VI expand the mixed myopathy/Ehlers-Danlos syndrome spectrum and lead to variant-specific alterations in the extracellular matrix Genet Med 22, 112-123, 2020. (Epub 2019 Jul 5)
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Del Valle, JR, Betts, BC, Yu, XZ, Janssens, S, Lambrecht, BN, Simon, MC, Hu, CA. Clarifying the translational potential of B-I09 Nat Chem Biol 16, 1152, 2020. (Epub 2020 Oct 16)
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Demeyer, A, Beyaert, R. Fragility can be a good thing in cancer Nat Immunol 21, 11-13, 2020. (Epub 2019 Dec 10)
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Demeyer, A, Driege, Y, Skordos, I, Coudenys, J, Lemeire, K, Elewaut, D, Staal, J, Beyaert, R. Long-Term MALT1 Inhibition in Adult Mice Without Severe Systemic Autoimmunity iScience 23, 101557, 2020. (Epub 2020 Sep 12)
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De Samber, B, De Rycke, R, De Bruyne, M, Kienhuis, M, Sandblad, L, Bohic, S, Cloetens, P, Urban, C, Polerecky, L, Vincze, L. Effect of sample preparation techniques upon single cell chemical imaging: A practical comparison between synchrotron radiation based X-ray fluorescence (SR-XRF) and Nanoscopic Secondary Ion Mass Spectrometry (nano-SIMS) Anal Chim Acta 1106, 22-32, 2020. (Epub 2020 Apr 15)
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De Samber, B, Vanden Berghe, T, Meul, E, Bauters, S, Seyrich, M, Smet, J, De Paepe, B, da Silva, JC, Bohic, S, Cloetens, P, Van Coster, R, Vandenabeele, P, Vincze, L. Nanoscopic X-ray imaging and quantification of the iron cellular architecture within single fibroblasts of Friedreich's ataxia patients J Synchrotron Radiat 27, 185-198, 2020. (Epub 2020 Jan 1)
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Deschoemaeker, S, Laoui, D. IFNgamma signaling response in peripheral blood monocytes: A new prognostic biomarker for breast cancer? EBioMedicine 53, 102690, 2020. (Epub 2020 Feb 25)
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De Schutter, E, Croes, L, Ibrahim, J, Pauwels, P, Op de Beeck, K, Vandenabeele, P, Van Camp, G. GSDME and its role in cancer: From behind the scenes to the front of the stage Int J Cancer , in press, 2020. (Epub 2020 Nov 13)
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De Smet, EG, Van Eeckhoutte, HP, Avila Cobos, F, Blomme, E, Verhamme, FM, Provoost, S, Verleden, SE, Venken, K, Maes, T, Joos, GF, Mestdagh, P, Brusselle, GG, Bracke, KR. The role of miR-155 in cigarette smoke-induced pulmonary inflammation and COPD Mucosal Immunol 13, 423-436, 2020. (Epub 2019 Dec 9)
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De Spiegeleer, A, Elewaut, D, Van Den Noortgate, N, Janssens, Y, Debunne, N, Van Langenhove, S, Govindarajan, S, De Spiegeleer, B, Wynendaele, E. Quorum sensing molecules as a novel microbial factor impacting muscle cells Biochim Biophys Acta Mol Basis Dis 1866, 165646, 2020. (Epub 2019 Dec 20)
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De Thaye, E, Van de Vijver, K, Van der Meulen, J, Taminau, J, Wagemans, G, Denys, H, Van Dorpe, J, Berx, G, Ceelen, W, Van Bocxlaer, J, De Wever, O. Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma Sci Rep 10, 6688, 2020. (Epub 2020 Apr 21)
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De Trez, C, Stijlemans, B, Bockstal, V, Cnops, J, Korf, H, Van Snick, J, Caljon, G, Muraille, E, Humphreys, IR, Boon, L, Van Ginderachter, JA, Magez, S. A Critical Blimp-1-Dependent IL-10 Regulatory Pathway in T Cells Protects From a Lethal Pro-inflammatory Cytokine Storm During Acute Experimental Trypanosoma brucei Infection Front Immunol 11, 1085, 2020. (Epub 2020 Jun 4)
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de Vasconcelos, NM, Lamkanfi, M. Recent Insights on Inflammasomes, Gasdermin Pores, and Pyroptosis Cold Spring Harb Perspect Biol 12, a036392, 2020. (Epub 2019 Sep 30)
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de Vasconcelos, NM, Van Opdenbosch, N, Van Gorp, H, Martin-Perez, R, Zecchin, A, Vandenabeele, P, Lamkanfi, M. An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages Cell Rep 32, 107959, 2020. (Epub 2020 Jul 28)
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De Vlaeminck, Y, Bonelli, S, Awad, RM, Dewilde, M, Rizzolio, S, Lecocq, Q, Bolli, E, Santos, AR, Laoui, D, Schoonooghe, S, Tamagnone, L, Goyvaerts, C, Mazzone, M, Breckpot, K, Van Ginderachter, JA. Targeting Neuropilin-1 with Nanobodies Reduces Colorectal Carcinoma Development Cancers (Basel) 12, 3582, 2020. (Epub 2020 Nov 30)
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