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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Dejonckheere, E, Vandenbroucke, RE, Libert, C. Matrix metalloproteinases as drug targets in ischaemia/reperfusion injury Drug Discov Today 16, 762-778, 2011. (Epub 2011 Jul 2) 
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De Koker, S, De Cock, LJ, Rivera Gil, P, Parak, WJ, Auzely Velty, R, Vervaet, C, Remon, JP, Grooten, J, De Geest, BG. Polymeric multilayer capsules delivering biotherapeutics Adv Drug Deliv Rev 63, 748-761, 2011. (Epub 2011 Apr 12)
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De Koker, S, Lambrecht, BN, Willart, MA, van Kooyk, Y, Grooten, J, Vervaet, C, Remon, JP, De Geest, BG. Designing polymeric particles for antigen delivery Chem Soc Rev 40, 320-339, 2011. (Epub 2010 Nov 9)
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De Temmerman, ML, Dewitte, H, Vandenbroucke, RE, Lucas, B, Libert, C, Demeester, J, De Smedt, SC, Lentacker, I, Rejman, J. mRNA-Lipoplex loaded microbubble contrast agents for ultrasound-assisted transfection of dendritic cells Biomaterials 32, 9128-9135, 2011. (Epub 2011 Aug 23)
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De Temmerman, ML, Rejman, J, Grooten, J, De Beer, T, Vervaet, C, Demeester, J, De Smedt, SC. Lyophilization of protein-loaded polyelectrolyte microcapsules Pharm Res 28, 1765-1773, 2011. (Epub 2011 Mar 18)
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Dhondt, J, Peeraer, E, Verheyen, A, Nuydens, R, Buysschaert, I, Poesen, K, Van Geyte, K, Beerens, M, Shibuya, M, Haigh, JJ, Meert, T, Carmeliet, P, Lambrechts, D. Neuronal FLT1 receptor and its selective ligand VEGF-B protect against retrograde degeneration of sensory neurons FASEB J 25, 1461-1473, 2011. (Epub 2011 Jan 19)
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Dierendonck, M, De Koker, S, De Rycke, R, Bogaert, P, Grooten, J, Vervaet, C, Remon, JP, De Geest, BG. Single-step formation of degradable intracellular biomolecule microreactors. ACS Nano 5, 6886-6893, 2011. (Epub 2011 Aug 25)
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Duprez, L, Takahashi, N, Van Hauwermeiren, F, Vandendriessche, B, Goossens, V, Vanden Berghe, T, Declercq, W, Libert, C, Cauwels, A, Vandenabeele, P. RIP Kinase-dependent necroptosis drives lethal systemic inflammatory response syndrome Immunity 35, 908-918, 2011. (Epub 2011 Dec 23)
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El Bakkouri, K, Descamps, F, De Filette, M, Smet, A, Festjens, E, Birkett, A, Van Rooijen, N, Verbeek, S, Fiers, W, Saelens, X. Universal vaccine based on ectodomain of Matrix Protein 2 of Influenza A: Fc receptors and alveolar macrophages mediate protection J Immunol 186, 1022-1031, 2011. (Epub 2010 Dec 17)
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Eliasson, DG, Helgeby, A, Schon, K, Nygren, C, El-Bakkouri, K, Fiers, W, Saelens, X, Lovgren, KK, Nystrom, I, Lycke, NY. A novel non-toxic combined CTA1-DD and ISCOMS adjuvant vector for effective mucosal immunization against influenza virus Vaccine 29, 3951-3961, 2011. (Epub 2011 Apr 7)
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Eriksson, JE, Vandenabeele, P. Workshop summary: cell death mechanisms controlled by the TNF family Adv Exp Med Biol 691, 585-588, 2011. (Epub 2011)
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Festjens, N, Bogaert, P, Batni, A, Houthuys, E, Plets, E, Vanderschaeghe, D, Laukens, B, Asselbergh, B, De Rycke, R, Willart, MA, Jacques, P, Elewaut, D, Brouckaert, P, Lambrecht, BN, Huygen, K, Callewaert, N. Disruption of the SapM locus in Mycobacterium bovis BCG improves its protective efficacy as a vaccine against M. tuberculosis EMBO Mol Med 3, 222-234, 2011. (Epub 2011 Jan 26)
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Fiers, W. Cytokine research in Belgium Cytok Growth Factor Rev 22, 255-256, 2011. (Epub 2011 Oct)
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Galluzzi, L, Vanden Berghe, T, Vanlangenakker, N, Buettner, S, Eisenberg, T, Vandenabeele, P, Madeo, F, Kroemer, G. Programmed necrosis from molecules to health and disease Int Rev Cell Mol Biol 289, 1-35, 2011. (Epub 2011 Jul 10)
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Gardam, S, Beyaert, R. The kinase NIK as a therapeutic target in multiple myeloma Expert Opin Ther Targets 15, 207-218, 2011. (Epub 2011 Jan 5)
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Garg, AD, Krysko, DV, Vandenabeele, P, Agostinis, P. DAMPs and PDT-mediated photo-oxidative stress: exploring the unknown Photochem Photobiol Sci 10, 670-680, 2011. (Epub 2011 Jan 24)
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Goossens, S, Janzen, V, Bartunkova, S, Yokomizo, T, Drogat, B, Crisan, M, Haigh, K, Seuntjens, E, Umans, L, Riedt, T, Bogaert, P, Haenebalcke, L, Berx, G, Dzierzak, E, Huylebroeck, D, Haigh, JJ. The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization Blood 117, 5620-5630, 2011. (Epub 2011 Feb 25)
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Guery, L, Benikhlef, N, Gautier, T, Paul, C, Jego, G, Dufour, E, Jacquel, A, Cally, R, Manoury, B, Vanden Berghe, T, Vandenabeele, P, Droin, N, Solary, E. Fine-tuning nucleophosmin in macrophage differentiation and activation Blood 118, 4694-4704, 2011. (Epub 2011 Aug 29)
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Herzog, D, Loetscher, P, van Hengel, J, Knusel, S, Brakebusch, C, Taylor, V, Suter, U, Relvas, JB. The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool J Neurosci 31, 5120-5130, 2011. (Epub 2011 Mar 30)
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Hillaire, MLB, van Eijk, M, van Trierum, SE, van Riel, D, Saelens, X, Romijn, RA, Hemrika, W, Fouchier, RAM, Kuiken, T, Osterhaus, ADME, Haagsman, HP, Rimmelzwaan, GF. Assessment of the antiviral properties of recombinant porcine SP-D against various Influenza A viruses in vitro PLoS One 6, e25005, 2011. (Epub 2011 Sep 14)
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Hoste, E, Kemperman, P, Devos, M, Denecker, G, Kezic, S, Yau, N, Gilbert, B, Lippens, S, De Groote, P, Roelandt, R, Van Damme, P, Gevaert, K, Presland, RB, Takahara, H, Puppels, G, Caspers, P, Vandenabeele, P, Declercq, W. Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin J Invest Dermatol 131, 2233-2241, 2011. (Epub 2011 Jun 9)
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Hulpiau, P, van Roy, F. New insights into the evolution of metazoan cadherins Mol Biol Evol 28, 647-657, 2011. (Epub 2010 Sep 3)
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Hultberg, A, Temperton, NJ, Rosseels, V, Koenders, M, Gonzalez-Pajuelo, M, Schepens, B, Ibanez, LI, Vanlandschoot, P, Schillemans, J, Saunders, M, Weiss, RA, Saelens, X, Melero, JA, Verrips, CT, Van Gucht, S, de Haard, HJ. Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules PLoS One 6, e17665, 2011. (Epub 2011 Apr 1)
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Ibanez, LI, De Filette, M, Hultberg, A, Verrips, T, Temperton, N, Weiss, RA, Vandevelde, W, Schepens, B, Vanlandschoot, P, Saelens, X. Nanobodies with in vitro neutralizing activity protect mice against H5N1 Influenza virus infection J Infect Dis 203, 1063-1072, 2011. (Epub 2011 Apr)
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Ivanova, S, Gregorc, U, Vidergar, N, Javier, R, Bredt, DS, Vandenabeele, P, Pardo, J, Simon, MM, Turk, V, Banks, L, Turk, B. MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis Cell Death Dis. 2, e116, 2011. (Epub 2011 Jan 20)
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Jackson, B, Peyrollier, K, Pedersen, E, Basse, A, Karlsson, R, Wang, Z, Lefever, T, Ochsenbein, A, Schmidt, G, Aktories, K, Stanley, A, Quondamatteo, F, Ladwein, M, Rottner, K, van Hengel, J, Brakebusch, C. RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes Mol Biol Cell 22, 593-605, 2011. (Epub 2011 Jan 5)
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Janssens, S, Crabbe, E, Vleminckx, K. The role of Wnt in cell signaling and cell adhesion during early vertebrate development Front Biosci 17, 2352-2366, 2011. (Epub 2011 Jun 1)
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Kantyka, T, Fischer, J, Wu, Z, Declercq, W, Reiss, K, Schroder, JM, Meyer-Hoffert, U. Inhibition of Kallikrein-related peptidases by the serine protease inhibitor of Kazal-type 6 Peptides 32, 1187-1192, 2011. (Epub 2011 Mar 22)
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Kersse, K, Bertrand, MJ, Lamkanfi, M, Vandenabeele, P. NOD-like receptors and the innate immune system: Coping with danger, damage and death Cytokine Growth Factor Rev 22, 257-276, 2011. (Epub 2011 Oct 11)
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Kersse, K, Lamkanfi, M, Bertrand, MJ, Vanden Berghe, T, Vandenabeele, P. Interaction patches of procaspase-1 CARD are differently involved in procaspase-1 activation and RIP2-dependent NF-KB signaling J Biol Chem 286, 35874-35882, 2011. (Epub 2011 Aug 23)
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Kersse, K, Verspurten, J, Vanden Berghe, T, Vandenabeele, P. The death-fold superfamily of homotypic interaction motifs Trends Biochem Sci 36, 541-552, 2011. (Epub 2011 Jul 26)
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Kool, M, van Loo, G, Waelput, W, De Prijck, S, Muskens, F, Sze, M, van Praet, J, Branco-Madeira, F, Janssens, S, Reizis, B, Elewaut, D, Beyaert, R, Hammad, H, Lambrecht, B. The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells and systemic autoimmunity Immunity 35, 82-96, 2011. (Epub 2011 Jun 30)
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Kool, M, Willart, MAM, van Nimwegen, M, Bergen, I, Pouliot, P, Virchow, JC, Rogers, N, Osorio, F, Reis e Souza, C, Hammad, H, Lambrecht, B. An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma Immunity 34, 527-540, 2011. (Epub 2011 Apr 7)
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Kroemer, G, Martinon, F, Lippens, S, Green, DR, Knight, R, Vandenabeele, P, Piacentini, M, Nagata, S, Borner, C, Simon, HU, Krammer, P, Melino, G. Jurg Tschopp 1951 2011 an immortal contribution Cell Death Differ 18, 1087-1088, 2011. (Epub 2011 Apr 29)
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Krysko, DV, Agostinis, P, Krysko, O, Garg, AD, Bachert, C, Lambrecht, BN, Vandenabeele, P. Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation Trends Immunol 32, 157-164, 2011. (Epub 2011 Feb 19)
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Krysko, DV, Kaczmarek, A, Krysko, O, Heyndrickx, L, Woznicki, J, Bogaert, P, Cauwels, A, Takahashi, N, Magez, S, Bachert, C, Vandenabeele, P. TLR-2 and TLR-9 are sensors of apoptosis in a mouse model of doxorubicin-induced acute inflammation Cell Death Differ 18, 1316-1325, 2011. (Epub 2011 Feb 11)
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Krysko, O, Holtappels, G, Zhang, N, Kubica, M, Deswarte, K, Derycke, L, Claeys, S, Hammad, H, Brusselle, GG, Vandenabeele, P, Krysko, DV, Bachert, C. Alternatively activated macrophages and impaired phagocytosis of S. aureus in chronic rhinosinusitis Allergy 66, 396-403, 2011. (Epub 2010 Oct 25)
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Laukens, B, Jennewein, C, Schenk, B, Vanlangenakker, N, Schier, A, Cristofanon, S, Zobel, K, Deshayes, K, Vucic, D, Jeremias, I, Bertrand, MJ, Vandenabeele, P, Fulda, S. Smac mimetic bypasses apoptosis resistance in FADD- or Caspase-8-deficient cells by priming for Tumor Necrosis Factor alpha-induced necroptosis Neoplasia 13, 971-979, 2011. (Epub 2011 Oct)
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Libert, C. Introduction to the session "Mechanisms of pathological and therapeuticeffects of the TNF family" Adv Exp Med Biol 691, 401-402, 2011. (Epub ---)
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Lippens, S, Hoste, E, Vandenabeele, P, Declercq, W. Cell death in the skin In Apoptosis: Physiology and pathology. (Reed, JC, Green, DR, eds.), Cambridge, Cambridge University Press, pp. 323-332, 2011. (Epub 2011) 
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Lippens, S, Lefebvre, S, Gilbert, B, Sze, M, Devos, M, Verhelst, K, Vereecke, L, Mc Guire, C, Guerin, C, Vandenabeele, P, Pasparakis, M, Mikkola, ML, Beyaert, R, Declercq, W, van Loo, G. Keratinocyte-specific ablation of the NF-?B regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis Cell Death Differ 18, 1845-1853, 2011. (Epub 2011 May 13)
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Matmati, M, Jacques, P, Maelfait, J, Verheugen, E, Kool, M, Sze, M, Geboes, L, Louagie, E, Mc Guire, C, Vereecke, L, Chu, Y, Boon, L, Staelens, S, Matthys, P, Lambrecht, B, Schmidt-Supprian, M, Pasparakis, M, Elewaut, D, Beyaert, R, van Loo, G. A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis Nature Genetics 43, 908-912, 2011. (Epub 2011 Aug 14)
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Mc Guire, C, Beyaert, R, van Loo, G. Death receptor signalling in central nervous system inflammation and demyelination Trends Neurosci 34, 619-628, 2011. (Epub 2011 Oct 13)
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Migliorini, D, Bogaerts, S, Defever, D, Vyas, R, Denecker, G, Radaelli, E, Zwolinska, A, Depaepe, V, Hochepied, T, Skarnes, WC, Marine, JC. Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice J Clin Invest 121, 1329-1343, 2011. (Epub 2011 Mar 14)
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Minamishima, S, Kida, K, Tokuda, K, Wang, H, Sips, PY, Kosug, iS, Mandeville, JB, Buys, ES, Brouckaert, P, Liu, PK, Liu, CH, Bloch, KD, Ichinose, F. Inhaled Nitric Oxide improves outcomes after successful cardiopulmonary resuscitation in mice Circulation 124, 1645-1653, 2011. (Epub 2011 Sep 19)
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Muller, K, Kainov, D, El Bakkouri, K, Saelens, X, De Brabander, J, Kittel, C, Samm, E, Muller, C. The proton translocation domain of cellular vacuolar ATPase provides a target for the treatment of influenza A virus infections Br J Pharmacol 164, 344-357, 2011. (Epub 2011 Mar 21)
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Nagasaka, Y, Buys, ES, Spagnolli, E, Steinbicker, AU, Hayton, SR, Rauwerdink, KM, Brouckaert, P, Zapol, WM, Bloch, KD. Soluble guanylate cyclase alpha1 is required for the cardioprotective effects of inhaled nitric oxide Am J Physiol Heart Circ Physiol 300, H1477-1483, 2011. (Epub 2011 Jan 21)
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Nagels, B, Santens, F, Weterings, K, Van Damme, EJ, Callewaert, N. Improved sample preparation for CE-LIF analysis of plant N-glycans Electrophoresis 32, 3482-3490 , 2011. (Epub 2011 Nov 21)
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Nagels, B, Van Damme, EJ, Pabst, M, Callewaert, N, Weterings, K. Production of complex multi-antennary N-glycans in Nicotiana benthamiana plants Plant Physiol 155, 1103-1112, 2011. (Epub 2011 Jan 13)
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Pauwels, NS, Bracke, KR, Dupont, LL, Van Pottelberge, GR, Provoost, S, Vanden Berghe, T, Vandenabeele, P, Lambrecht, BN, Joos, GF, Brusselle, GG. Role of IL-1alpha and the Nlrp3/caspase-1/IL-1beta axis in cigarette smoke-induced pulmonary inflammation and COPD Eur Respir J 38, 1019-1028, 2011. (Epub 2011 May 26)
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