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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Hultberg, A, Temperton, NJ, Rosseels, V, Koenders, M, Gonzalez-Pajuelo, M, Schepens, B, Ibanez, LI, Vanlandschoot, P, Schillemans, J, Saunders, M, Weiss, RA, Saelens, X, Melero, JA, Verrips, CT, Van Gucht, S, de Haard, HJ. Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules PLoS One 6, e17665, 2011. (Epub 2011 Apr 1) 
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Ibanez, LI, De Filette, M, Hultberg, A, Verrips, T, Temperton, N, Weiss, RA, Vandevelde, W, Schepens, B, Vanlandschoot, P, Saelens, X. Nanobodies with in vitro neutralizing activity protect mice against H5N1 Influenza virus infection J Infect Dis 203, 1063-1072, 2011. (Epub 2011 Apr)
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Ivanova, S, Gregorc, U, Vidergar, N, Javier, R, Bredt, DS, Vandenabeele, P, Pardo, J, Simon, MM, Turk, V, Banks, L, Turk, B. MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis Cell Death Dis. 2, e116, 2011. (Epub 2011 Jan 20)
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Jackson, B, Peyrollier, K, Pedersen, E, Basse, A, Karlsson, R, Wang, Z, Lefever, T, Ochsenbein, A, Schmidt, G, Aktories, K, Stanley, A, Quondamatteo, F, Ladwein, M, Rottner, K, van Hengel, J, Brakebusch, C. RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes Mol Biol Cell 22, 593-605, 2011. (Epub 2011 Jan 5)
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Janssens, S, Crabbe, E, Vleminckx, K. The role of Wnt in cell signaling and cell adhesion during early vertebrate development Front Biosci 17, 2352-2366, 2011. (Epub 2011 Jun 1)
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Kantyka, T, Fischer, J, Wu, Z, Declercq, W, Reiss, K, Schroder, JM, Meyer-Hoffert, U. Inhibition of Kallikrein-related peptidases by the serine protease inhibitor of Kazal-type 6 Peptides 32, 1187-1192, 2011. (Epub 2011 Mar 22)
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Kersse, K, Bertrand, MJ, Lamkanfi, M, Vandenabeele, P. NOD-like receptors and the innate immune system: Coping with danger, damage and death Cytokine Growth Factor Rev 22, 257-276, 2011. (Epub 2011 Oct 11)
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Kersse, K, Lamkanfi, M, Bertrand, MJ, Vanden Berghe, T, Vandenabeele, P. Interaction patches of procaspase-1 CARD are differently involved in procaspase-1 activation and RIP2-dependent NF-KB signaling J Biol Chem 286, 35874-35882, 2011. (Epub 2011 Aug 23)
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Kersse, K, Verspurten, J, Vanden Berghe, T, Vandenabeele, P. The death-fold superfamily of homotypic interaction motifs Trends Biochem Sci 36, 541-552, 2011. (Epub 2011 Jul 26)
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Kool, M, van Loo, G, Waelput, W, De Prijck, S, Muskens, F, Sze, M, van Praet, J, Branco-Madeira, F, Janssens, S, Reizis, B, Elewaut, D, Beyaert, R, Hammad, H, Lambrecht, B. The ubiquitin-editing protein A20 prevents dendritic cell activation, recognition of apoptotic cells and systemic autoimmunity Immunity 35, 82-96, 2011. (Epub 2011 Jun 30)
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Kool, M, Willart, MAM, van Nimwegen, M, Bergen, I, Pouliot, P, Virchow, JC, Rogers, N, Osorio, F, Reis e Souza, C, Hammad, H, Lambrecht, B. An unexpected role for uric acid as an inducer of T helper 2 cell immunity to inhaled antigens and inflammatory mediator of allergic asthma Immunity 34, 527-540, 2011. (Epub 2011 Apr 7)
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Kroemer, G, Martinon, F, Lippens, S, Green, DR, Knight, R, Vandenabeele, P, Piacentini, M, Nagata, S, Borner, C, Simon, HU, Krammer, P, Melino, G. Jurg Tschopp 1951 2011 an immortal contribution Cell Death Differ 18, 1087-1088, 2011. (Epub 2011 Apr 29)
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Krysko, DV, Agostinis, P, Krysko, O, Garg, AD, Bachert, C, Lambrecht, BN, Vandenabeele, P. Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation Trends Immunol 32, 157-164, 2011. (Epub 2011 Feb 19)
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Krysko, DV, Kaczmarek, A, Krysko, O, Heyndrickx, L, Woznicki, J, Bogaert, P, Cauwels, A, Takahashi, N, Magez, S, Bachert, C, Vandenabeele, P. TLR-2 and TLR-9 are sensors of apoptosis in a mouse model of doxorubicin-induced acute inflammation Cell Death Differ 18, 1316-1325, 2011. (Epub 2011 Feb 11)
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Krysko, O, Holtappels, G, Zhang, N, Kubica, M, Deswarte, K, Derycke, L, Claeys, S, Hammad, H, Brusselle, GG, Vandenabeele, P, Krysko, DV, Bachert, C. Alternatively activated macrophages and impaired phagocytosis of S. aureus in chronic rhinosinusitis Allergy 66, 396-403, 2011. (Epub 2010 Oct 25)
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Laukens, B, Jennewein, C, Schenk, B, Vanlangenakker, N, Schier, A, Cristofanon, S, Zobel, K, Deshayes, K, Vucic, D, Jeremias, I, Bertrand, MJ, Vandenabeele, P, Fulda, S. Smac mimetic bypasses apoptosis resistance in FADD- or Caspase-8-deficient cells by priming for Tumor Necrosis Factor alpha-induced necroptosis Neoplasia 13, 971-979, 2011. (Epub 2011 Oct)
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Libert, C. Introduction to the session "Mechanisms of pathological and therapeuticeffects of the TNF family" Adv Exp Med Biol 691, 401-402, 2011. (Epub ---)
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Lippens, S, Hoste, E, Vandenabeele, P, Declercq, W. Cell death in the skin In Apoptosis: Physiology and pathology. (Reed, JC, Green, DR, eds.), Cambridge, Cambridge University Press, pp. 323-332, 2011. (Epub 2011) 
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Lippens, S, Lefebvre, S, Gilbert, B, Sze, M, Devos, M, Verhelst, K, Vereecke, L, Mc Guire, C, Guerin, C, Vandenabeele, P, Pasparakis, M, Mikkola, ML, Beyaert, R, Declercq, W, van Loo, G. Keratinocyte-specific ablation of the NF-?B regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis Cell Death Differ 18, 1845-1853, 2011. (Epub 2011 May 13)
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Matmati, M, Jacques, P, Maelfait, J, Verheugen, E, Kool, M, Sze, M, Geboes, L, Louagie, E, Mc Guire, C, Vereecke, L, Chu, Y, Boon, L, Staelens, S, Matthys, P, Lambrecht, B, Schmidt-Supprian, M, Pasparakis, M, Elewaut, D, Beyaert, R, van Loo, G. A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis Nature Genetics 43, 908-912, 2011. (Epub 2011 Aug 14)
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Mc Guire, C, Beyaert, R, van Loo, G. Death receptor signalling in central nervous system inflammation and demyelination Trends Neurosci 34, 619-628, 2011. (Epub 2011 Oct 13)
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Migliorini, D, Bogaerts, S, Defever, D, Vyas, R, Denecker, G, Radaelli, E, Zwolinska, A, Depaepe, V, Hochepied, T, Skarnes, WC, Marine, JC. Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice J Clin Invest 121, 1329-1343, 2011. (Epub 2011 Mar 14)
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Minamishima, S, Kida, K, Tokuda, K, Wang, H, Sips, PY, Kosug, iS, Mandeville, JB, Buys, ES, Brouckaert, P, Liu, PK, Liu, CH, Bloch, KD, Ichinose, F. Inhaled Nitric Oxide improves outcomes after successful cardiopulmonary resuscitation in mice Circulation 124, 1645-1653, 2011. (Epub 2011 Sep 19)
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Muller, K, Kainov, D, El Bakkouri, K, Saelens, X, De Brabander, J, Kittel, C, Samm, E, Muller, C. The proton translocation domain of cellular vacuolar ATPase provides a target for the treatment of influenza A virus infections Br J Pharmacol 164, 344-357, 2011. (Epub 2011 Mar 21)
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Nagasaka, Y, Buys, ES, Spagnolli, E, Steinbicker, AU, Hayton, SR, Rauwerdink, KM, Brouckaert, P, Zapol, WM, Bloch, KD. Soluble guanylate cyclase alpha1 is required for the cardioprotective effects of inhaled nitric oxide Am J Physiol Heart Circ Physiol 300, H1477-1483, 2011. (Epub 2011 Jan 21)
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Nagels, B, Santens, F, Weterings, K, Van Damme, EJ, Callewaert, N. Improved sample preparation for CE-LIF analysis of plant N-glycans Electrophoresis 32, 3482-3490 , 2011. (Epub 2011 Nov 21)
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Nagels, B, Van Damme, EJ, Pabst, M, Callewaert, N, Weterings, K. Production of complex multi-antennary N-glycans in Nicotiana benthamiana plants Plant Physiol 155, 1103-1112, 2011. (Epub 2011 Jan 13)
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Pauwels, NS, Bracke, KR, Dupont, LL, Van Pottelberge, GR, Provoost, S, Vanden Berghe, T, Vandenabeele, P, Lambrecht, BN, Joos, GF, Brusselle, GG. Role of IL-1alpha and the Nlrp3/caspase-1/IL-1beta axis in cigarette smoke-induced pulmonary inflammation and COPD Eur Respir J 38, 1019-1028, 2011. (Epub 2011 May 26)
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Pinheiro, I, Dejager, L, Libert, C. X-chromosome-located microRNAs in immunity: Might they explain male/female differences?: The X chromosome-genomic context may affect X-located miRNAs and downstream signaling, thereby contributing to the enhanced immune response of females Bioessays 33, 791-802, 2011. (Epub 2011 Sep 28)
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Pourebrahim, R, Houtmeyers, R, Ghogomu, S, Janssens, S, Thelie, A, Tran, HT, Langenberg, T, Vleminckx, K, Bellefroid, E, Cassiman, JJ, Tejpar, S. Transcription factor Zic2 inhibits Wnt/beta-catenin signaling J Biol Chem 286, 37732-37740, 2011. (Epub 2011 Sep 9)
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Provoost, S, Maes, T, Pauwels, NS, Vanden Berghe, T, Vandenabeele, P, Lambrecht, BN, Joos, GF, Tournoy, KG. NLRP3/Caspase-1-independent IL-1beta production mediates diesel exhaust particle-induced pulmonary inflammation J Immunol 187, 3331-3337, 2011. (Epub 2011 Aug 15)
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Raasch, J, Zeller, N, van Loo, G, Merkler, D, Mildner, A, Erny, D, Knobeloch, KP, Bethea, JR, Waisman, A, Knust, M, Del Turco, D, Deller, T, Blank, T, Priller, J, Brück, W, Pasparakis, M, Prinz, M. IkB kinase 2 determines oligodendrocyte loss by non cell-autonomous activation of NF-kB in the central nervous system Brain 134, 1184-1198, 2011. (Epub 2011 Feb 10)
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Remijsen, Q, Kuijpers, TW, Wirawan, E, Lippens, S, Vandenabeele, P, Vanden Berghe, T. Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality Cell Death Differ 18, 81-588, 2011. (Epub 2011 Feb 4)
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Remijsen, Q, Vanden Berghe, T, Wirawan, E, Asselbergh, B, Parthoens, E, De Rycke, R, Noppen, S, Delforge, M, Willems, J, Vandenabeele, P. Neutrophil extracellular trap cell death requires both autophagy and superoxide generation Cell Res 21, 290-304, 2011. (Epub 2010 Nov 9)
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Rohn, TT, Wirawan, E, Brown, RJ, Harris, JR, Masliah, E, Vandenabeele, P. Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain Neurobiol Dis 43, 68-78, 2011. (Epub 2010 Nov 13)
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Ruiz de Almodovar, C, Fabre, PJ, Knevels, E, Coulon, C, Segura, I, Haddick, PC, Aerts, L, Delattin, N, Strasser, G, Oh, WJ, Lange, C, Vinckier, S, Haigh, J, Fouquet, C, Gu, C, Alitalo, K, Castellani, V, Tessier-Lavigne, M, Chedotal, A, et al.. VEGF mediates commissural axon chemoattraction through its receptor Flk1 Neuron 70, 966-978, 2011. (Epub 2011 Jun 9)
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Schepens, B, Ibanez, LI, De Baets, S, Hultberg, A, Bogaert, P, De Bleser, P, Vervalle, F, Verrips, T, Melero, J, Vandevelde, W, Vanlandschoot, P, Saelens, X. Nanobodies(R) specific for Respiratory Syncytial Virus fusion protein protect against infection by inhibition of fusion J Infect Dis 204, 1692-1701, 2011. (Epub 2011 Oct 12)
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Sips, PY, Brouckaert, P, Ichinose, F. The alpha1 isoform of soluble guanylate cyclase regulates cardiac contractility but is not required for ischemic preconditioning Basic Res Cardiol 106, 635-643, 2011. (Epub 2011 Mar 11)
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Staal, J, Bekaert, T, Beyaert, R. Regulation of NF-kB signalling by caspases and MALT1 paracaspase Cell Res 21, 40-54, 2011. (Epub 2010 Nov 30)
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Staal, J, Driege, Y, Bekaert, T, Demeyer, A, Muyllaert, D, Van Damme, P, Gevaert, K, Beyaert, R. T cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1 EMBO J 30, 1742-1752, 2011. (Epub 2011 Mar 29)
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Steinbicker, AU, Liu, H, Jiramongkolchai, K, Malhotra, R, Choe, EY, Busch, CJ, Graveline, AR, Kao, SM, Nagasaka, Y, Ichinose, F, Buys, ES, Brouckaert, P, Zapol, WM, Bloch, KD. Nitric oxide regulates pulmonary vascular smooth muscle cell expression of the inducible cAMP early repressor gene Nitric Oxide 25, 294-302, 2011. (Epub 2011 May 27)
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Taganna, J, de Boer, AR, Wuhrer, M, Bouckaert, J. Glycosylation changes as important factors for the susceptibility to urinary tract infection Biochem Soc Trans 39, 349-354, 2011. (Epub 2011 Jan)
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Thimiri Govinda Raj, DB, Ghesquière, B, Tharkeshwar, AK, Coen, K, Derua, R, Vanderschaeghe, D, Rysman, E, Bagadi, R, Baatsens, P, De Strooper, B, Waelkens, E, Borghs, G, Callewaert, N, Swinnen, J, Gevaert, K, Annaert, W. A novel strategy for the comprehensive analysis of the biomolecular composition of isolated plasmamembranes Mol Syst Biol 7, 541, 2011. (Epub 2011 Oct 25)
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Tran, HT, Delvaeye, M, Verschuere, V, Descamps, E, Crabbe, E, Van Hoorebeke, L, McCrea, P, Adriaens, D, Van Roy, F, Vleminckx, K. ARVCF depletion cooperates with Tbx1 deficiency in the development of 22q11.2DS-like phenotypes in Xenopus Dev Dynam 240, 2680-2687, 2011. (Epub 2011 Oct 25)
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Tran, HT, Vleminckx, K. You'd better catch that Wnt: primitive hematopoiesis requires canonical Wnt signaling Cell Cycle 10, 366-367, 2011. (Epub 2011 Feb 1)
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Van Bogaert, T, Vandevyver, S, Dejager, L, Van Hauwermeiren, F, Pinheiro, I, Petta, I, Engblom, D, Kleyman, A, Schütz, G, Tuckermann, J, Libert, C. TNF inhibits glucocorticoid receptor function in mice: A strong signal towards lethal shock J Biol Chem 286, 26555-26567, 2011. (Epub 2011 Jun 6)
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Vanbokhoven, H, Melino, G, Candi, E, Declercq, W. p63, a story of mice and men J Invest Dermatol 131, 1196-1207, 2011. (Epub 2011 Apr 7)
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Vandenbroucke, R, Dejonckheere, E, Libert, C. A therapeutic role for MMP inhibitors in lung diseases? Eur Respir J 38, 1200-1214, 2011. (Epub 2011 Jun 9)
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Vandenbroucke, RE, Dejager, L, Libert, C. The first MMP in sepsis EMBO Mol Med 3, 367-369, 2011. (Epub 2011 May 18)
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Vander Beken, S, Al Dulayymi, JR, Naessens, T, Koza, G, Maza-Iglesias, M, Rowles, R, Theunissen, C, De Medts, J, Lanckacker, E, Baird, MS, Grooten, J. Molecular structure of the Mycobacterium tuberculosis virulence factor, mycolic acid, determines the elicited inflammatory pattern Eur J Immunol 41, 450-460, 2011. (Epub 2010 Dec 9)
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