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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Vandenbroucke, K, Hans, W, Van Huysse, J, Neirynck, S, Demetter, P, Remaut, E, Rottiers, P, Steidler, L. Active delivery of trefoil factors by genetically modified Lactococcus lactis prevents and heals acute colitis in mice Gastroenterology 127, 502-513, 2004. (Epub ---) 
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Vanderheyde, N, Vandenabeele, P, Goldman, M, Willems, F. Distinct mechanisms are involved in tumoristatic and tumoricidal activities of monocyte-derived dendritic cells Immunol Lett 91, 99-101, 2004. (Epub ---)
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Van de Wiele, C, Goethals, I, Audenart, K, Otte, A, Mertens, N. Molecular aspects of G-protein coupled receptor signalling of relevance for nuclear medicine imaging in psychiatry In Nuclear Medicine in Psychiatry. (Otte, A., ed.), Berlin, Springer Verlag, pp. 45-56, 2004. (Epub ---) 
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Van de Wiele, C, Revets, H, Mertens, N. Radioimmunoimaging. Advances and prospects Q J Nucl Med Mol Imaging 48, 317-325, 2004. (Epub ---)
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Van de Wiele, C, Vermeersch, H, Loose, D, Signore, A, Mertens, N, Dierckx, R. Radiolabeled annexin-V for monitoring treatment response in oncology Cancer Biother Radiopharm 19, 189-194, 2004. (Epub ---)
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van Dijk, M, Mulders, J, Könst, A, Janssens, B, van Roy, F, Blankenstein, M, Oudejans, C. Differential downregulation of alpha-T-catenin expression in placenta: trophoblast cell type-dependent imprinting of the CTNNA3 gene Gene Expr Patterns 5, 61-65, 2004. (Epub ---)
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Van Gele, M, Boyle, GM, Cook, AL, Vandesompele, J, Boonefaes, T, Rottiers, P, Van Roy, N, De Paepe, A, Parsons, PG, Leonard, JH, Speleman, F. Gene-expression profiling reveals distinct expression patterns for Classic versus Variant Merkel cell phenotypes and new classifier genes to distinguish Merkel cell from small-cell lung carcinoma Oncogene 23, 2732-2742, 2004. (Epub ---)
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Van Laethem, A, Van Kelst, S, Lippens, S, Declercq, W, Vandenabeele, P, Janssens, S, Vandenheede, JR, Garmyn, M, Agostinis, P. Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes FASEB J 18, 1946-1948, 2004. (Epub 2004 Sep 23)
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Vanpoucke, G, Goossens, S, De Craene, B, Gilbert, B, van Roy, F, Berx, G. GATA-4 and MEF2C transcription factors control the tissue-specific expression of the alpha T-catenin gene CTNNA3 Nucleic Acids Res 32, 4155-4165, 2004. (Epub ---)
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Vekemans, K, Braet, F, Muyllaert, D, Wisse, E. Nitric oxide from rat liver sinusoidal endothelial cells induces apoptosis in IFNgamma-sensitized CC531s colon carcinoma cells J Hepatol 41, 11-18, 2004. (Epub ---)
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Vervecken, W, Kaigorodov, V, Callewaert, N, Geysens, S, De Vusser, K, Contreras, R. In vivo synthesis of mammalian like hybrid type N-glycans in Pichia pastoris Appl Environm Microbiol 70, 2639-2646, 2004. (Epub ---)
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Vántus, T, Vertommen, D, Saelens, X, Rykx, A, De Kimpe, L, Vancauwenbergh, S, Mikhalap, S, Waelkens, E, Kéri, G, Seufferlein, T, Vandenabeele, P, Rider, M, Vandenheede, J, Van Lint, J. Doxorubicin-induced activation of protein kinase D1 through caspase-mediated proteolytic cleavage: Identification of two cleavage sites by microsequencing Cell Signal 16, 703-709, 2004. (Epub ---)
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Wielockx, B, Libert, C, Wilson, C. Matrilysin (Matrix Metalloproteinase-7): a new promising drug target in cancer and inflammation? Cytokine Growth Factor Rev 15, 111-115, 2004. (Epub ---)
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Woronowicz, A, De Vusser, K, Laroy, W, Contreras, R, Meakin, S, Ross, G, Szewczuk, M. Trypanosome trans-sialidase targets TrkA tyrosine kinase receptor and induces receptor internalization and activation Glycobiology 14, 987-998, 2004. (Epub 2004 Jul 7)
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Wu, G, Brouckaert, P, Olivecrona, T. Rapid down-regulation of adipose tissue lipoprotein lipase activity on food deprivation. Evidence that TNF- is involved Am J Physiol Endocrinol Metab 286, E711–E717, 2004. (Epub 2003 Dec 23)
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Assefa, Z, Garmyn, M, Vantieghem, A, Declercq, W, Vandenabeele, P, Vandenheede, JR, Agostinis, P. Ultraviolet B radiation-induced apoptosis in human keratinocytes: Cytosolic activation of procaspase-8 and the role of Bcl-2 FEBS Lett 540, 125-132, 2003. (Epub ---)
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Beyaert, R. (editor) Nuclear factor kB: Regulation and role in disease. Kluwer Academic Publishers, Dordrecht, (440 pages), 2003. (Epub ---)
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Bonné, S, Gilbert, B, Hatzfeld, M, Chen, X, Green, KJ, van Roy, F. Defining desmosomal plakophilin-3 interactions J Cell Biol 161, 403-416, 2003. (Epub 2003 Apr 21)
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Braet, F, Fraser, R, McCuskey, R. Thirty-five years of liver sinusoidal cells: Eddie Wisse in retirement Hepatology 38, 1057-1059, 2003. (Epub ---)
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Burns, K, Janssens, S, Brissoni, B, Olivos, N, Beyaert, R, Tschopp, J. Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4 J Exp Med 197, 263-268, 2003. (Epub ---)
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Callewaert, N, Schollen, E, Vanhecke, A, Jaeken, J, Matthijs, G, Contreras, R. Increased fucosylation and reduced branching of serum glycoprotein N-glycans in all known subtypes of congenital disorder of glycosylation I Glycobiology 13, 367-375, 2003. (Epub 2003 Jan 22)
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Carpentier, I, Janssens, S, Heyninck, K, Beyaert, R. NF-kB activation by Tumor Necrosis Factor and Interleukin-1 In Nuclear Factor kB: Regulation and role in disease. (Beyaert, R, ed.), Dordrecht, Kluwer Academic Publishers, pp. 49-67, 2003. (Epub ---)
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Cauwels, A, Janssen, B, Waeytens, A, Cuvelier, C, Brouckaert, P. Caspase inhibition causes hyperacute tumor necrosis factor-induced shock via oxidative stress and phospholipase A2 Nat Immunol 4, 387-393, 2003. (Epub ---)
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Chen, C, Dewaele, S, Braeckman, B, Desmyter, L, Verstraelen, J, Borgonie, G, Vanfleteren, J, Contreras, R. A high-throughput screening system for genes extending life-span Exp Gerontol 38, 1051-1063, 2003. (Epub ---)
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Colpaert, CG, Vermeulen, PB, Benoy, I, Soubry, A, Van Roy, F, van Beest, P, Goovaerts, G, Dirix, LY, Van Dam, P, Fox, SB, Harris, AL, Van Marck, EA. Inflammatory breast cancer shows angiogenesis with high endothelial proliferation rate and strong E-cadherin expression Br J Cancer 88, 718-725, 2003. (Epub ---)
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Colpaert, C, Vermeulen, PB, Van Beest, P, Soubry, A, Goovaerts, G, Dirix, L, Harris, AL, Van Marck, EA. Cutaneous breast cancer deposits show distinct growth patterns with different degrees of angiogenesis, hypoxia and fibrin deposition Histopathology 42, 530-540, 2003. (Epub ---)
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De Bosscher, K, Vanden Berghe, W, Haegeman, G. Regulation of NF-kB by glucocorticoids In Nuclear Factor kB: Regulation and role in disease. (Beyaert, R, ed.), Kluwer Academic Publishers, Dordrecht, pp. 221-239, 2003. (Epub ---)
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De Bosscher, K, Vanden Berghe, W, Haegeman, G. The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression Endocrine Rev 24, 488-522, 2003. (Epub ---)
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Debruyne, PR, Vermeulen, SJ, Berx, G, Pocard, M, Correia Da Rocha, AS, Li, X, Cirnes, L, Poupon, MF, Van Roy, FM, Mareel, MM. Functional and molecular characterization of the epithelioid to round transition in human colorectal cancer LoVo cells Oncogene 22, 7199-7208, 2003. (Epub ---)
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Devos, S, De Bosscher, K, Staels, B, Bauer, E, Roels, F, Vanden Berghe, W, Haegeman, G, Hooghe, R, Hooghe-Peters, EL. Inhibition of cytokine production by the herbicide atrazine. Search for nuclear receptor targets Biochem Pharmacol 65, 303-308, 2003. (Epub ---)
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D'Haeze, W, De Rycke, R, Mathis, R, Goormachtig, S, Pagnotta, S, Verplancke, C, Capoen, W, Holsters, M. Reactive oxygen species and ethylene play a positive role in lateral root base nodulation of a semiaquatic legume Proceedings of the National Academy of Sciences of the United States of America 100, 11789-11794, 2003. (Epub 2003 Sep 30)
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Evans, PC, Smith, TS, Lai, MJ, Williams, MG, Burke, DF, Heyninck, K, Kreike, MM, Beyaert, R, Blundell, TL, Kilshaw, PJ. A novel type of deubiquitinating enzyme J Biol Chem 278, 23180-23186, 2003. (Epub 2003 Apr 7)
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Frame, MJ, Tate, R, Adams, DR, Morgan, KM, Houslay, MD, Vandenabeele, P, Pyne, NJ. Interaction of caspase-3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1) Eur J Biochem 270, 962-970, 2003. (Epub ---)
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Fratelli, M, Minto, M, Crespi, A, Erba, E, Vandenabeele, P, Del Soldato, P, Ghezzi, P. Inhibition of nuclear factor-kB by a nitro-derivative of flurbiprofen: A possible mechanism for antiinflammatory and antiproliferative effect Antioxid Redox Signal 5, 229-235, 2003. (Epub ---)
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Geldhof, P, Vercauteren, I, Knox, D, Demaere, V, Van Zeveren, A, Berx, G, Vercruysse, J, Claerebout, E. Protein disulphide isomerase of Ostertagia ostertagi: An excretory-secretory product of L4 and adult worms? Int J Parasitol 33, 129-136, 2003. (Epub ---)
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Grille, SJ, Bellacosa, A, Upson, J, Klein-Szanto, AJ, van Roy, F, Lee-Kwon, W, Donowitz, M, Tsichlis, PN, Larue, L. The protein kinase Akt induces epithelial mesenchymal transition and promotes enhanced motility and invasiveness of squamous cell carcinoma lines Cancer Res 63, 2172-2178, 2003. (Epub ---)
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Heirman, I, Grooten, J. Eicosanoid mediators in health, inflammation and cancer Recent Res Devel Cell Biol 1, 177-201, 2003. (Epub ---)
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Heyninck, K, Kreike, MM, Beyaert, R. Structure-function analysis of the A20-binding inhibitor of NF-kB activation, ABIN-1 FEBS Lett 536, 135-140, 2003. (Epub ---)
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Heyninck, K, Wullaert, A, Beyaert, R. Nuclear factor-kappa B plays a central role in tumour necrosis factor-mediated liver disease Biochem Pharmacol 66, 1409-1415, 2003. (Epub ---)
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Hochepied, T, Berger, FG, Baumann, H, Libert, C. a1-Acid glycoprotein: An acute phase protein with inflammatory and immunomodulating properties Cytokine Growth Factor Rev 14, 25-34, 2003. (Epub ---)
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Hunter, I, Cobban, HJ, Vandenabeele, P, MacEwan, DJ, Nixon, GF. Tumor necrosis factor-alpha-induced activation of RhoA in airway smooth muscle cells: Role in the Ca2+ sensitization of myosin light chain20 phosphorylation Mol Pharmacol 63, 714-721, 2003. (Epub ---)
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Janssens, B, Mohapatra, B, Vatta, M, Goossens, S, Vanpoucke, G, Kools, P, Montoye, T, van Hengel, J, Bowles, NE, van Roy, F, Towbin, JA. Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathy Hum Genet 112, 227-236, 2003. (Epub 2002 Dec 5)
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Janssens, S, Beyaert, R. Functional diversity and regulation of different interleukin-1 receptor-associated kinase (IRAK) family members Mol Cell 11, 293-302, 2003. (Epub ---)
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Janssens, S, Beyaert, R. Role of Toll-like receptors in pathogen recognition Clin Microbiol Rev 16, 637-646, 2003. (Epub ---)
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Janssens, S, Burns, K, Vercammen, E, Tschopp, J, Beyaert, R. MyD88S, a splice variant of MyD88, differentially modulates NF-kappaB- and AP-1-dependent gene expression FEBS Lett 548, 103-107, 2003. (Epub ---)
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Jupp, OJ, Vandenabeele, P, MacEwan, DJ. Distinct regulation of cytosolic phospholipase A2 phosphorylation, translocation, proteolysis and activation by tumour necrosis factor-receptor subtypes Biochem J 374, 453-461, 2003. (Epub ---)
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Kahns, S, Kalai, M, Jakobsen, LD, Clark, BFC, Vandenabeele, P, Jensen, PH. Caspase-1 and caspase-8 cleave and inactivate cellular parkin J Biol Chem 278, 23376-23380, 2003. (Epub 2003 Apr 11)
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Kalai, M, Lamkanfi, M, Denecker, G, Boogmans, M, Lippens, S, Meeus, A, Declercq, W, Vandenabeele, P. Regulation of the expression and processing of caspase-12 J Cell Biol 162, 457-467, 2003. (Epub 2003 Jul 28)
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Krysko, DV, Brouckaert, G, Kalai, M, Vandenabeele, P, D'Herde, K. Mechanisms of internalization of apoptotic and necrotic L929 cells by a macrophage cell line studied by electron microscopy J Morphol 258, 336-345, 2003. (Epub 2003 Sep 30)
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Lambert, V, Wielockx, B, Munaut, C, Galopin, C, Jost, M, Itoh, T, Werb, Z, Baker, A, Libert, C, Krell, H-W, Foidart, J-M, Noël, A, Rakic, J-M. MMP-2 and MMP-9 synergize in promoting choroidal neovascularization FASEB J 17, 2290-2292, 2003. (Epub ---)
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