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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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De Volder, J, Vereecke, L, Joos, G, Maes, T. Targeting neutrophils in asthma: a therapeutic opportunity? Biochem Pharmacol 182, 114292, 2020. (Epub 2020 Oct 17) 
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Devos, M, Tanghe, G, Gilbert, B, Dierick, E, Verheirstraeten, M, Nemegeer, J, de Reuver, R, Lefebvre, S, De Munck, J, Rehwinkel, J, Vandenabeele, P, Declercq, W, Maelfait, J. Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation J Exp Med 217, e20191913, 2020. (Epub 2020 Apr 21)
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Devos, T, Geukens, T, Schauwvlieghe, A, Arien, KK, Barbezange, C, Cleeren, M, Compernolle, V, Dauby, N, Desmecht, D, Grimaldi, D, Lambrecht, BN, Luyten, A, Maes, P, Moutschen, M, Romano, M, Seyler, L, Nevessignsky, MT, Vandenberghe, K, van Griensven, J, et al.. A randomized, multicentre, open-label phase II proof-of-concept trial investigating the clinical efficacy and safety of the addition of convalescent plasma to the standard of care in patients hospitalized with COVID-19: the Donated Antibodies Working against nCoV (DAWn-Plasma) trial Trials 21, 981, 2020. (Epub 2020 Nov 27)
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Dhont, S, Derom, E, Van Braeckel, E, Depuydt, P, Lambrecht, BN. The pathophysiology of 'happy' hypoxemia in COVID-19 Respir Res 21, 198, 2020. (Epub 2020 JUl 28)
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D'Huyvetter, M, De Vos, J, Caveliers, V, Vaneycken, I, Heemskerk, J, Duhoux, FP, Fontaine, C, Vanhoeij, M, Windhorst, AD, van der Aa, F, Hendrikse, NH, Eersels, JLE, Everaert, H, Gykiere, P, Devoogdt, N, Raes, G, Lahoutte, T, Keyaerts, M. Phase I trial of (131)I-GMIB-Anti-HER2-VHH1, a new promising candidate for HER2-targeted radionuclide therapy in breast cancer patients J Nucl Med , in press, 2020. (Epub 2020 Dec 4)
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Dougados, M, Wei, JC, Landewe, R, Sieper, J, Baraliakos, X, Van den Bosch, F, Maksymowych, WP, Ermann, J, Walsh, JA, Tomita, T, Deodhar, A, van der Heijde, D, Li, X, Zhao, F, Bertram, CC, Gallo, G, Carlier, H, Gensler, LS, Coast, V, et al.. Efficacy and safety of ixekizumab through 52 weeks in two phase 3, randomised, controlled clinical trials in patients with active radiographic axial spondyloarthritis (COAST-V and COAST-W) Ann Rheum Dis 79, 176-185, 2020. (Epub 2019 Nov 4)
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Dumas, E, Venken, K, Rosenbaum, JT, Elewaut, D. Intestinal Microbiota, HLA-B27, and Spondyloarthritis: Dangerous Liaisons Rheum Dis Clin North Am 46, 213-224, 2020. (Epub 2020 May)
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Efimova, I, Catanzaro, E, Van der Meeren, L, Turubanova, VD, Hammad, H, Mishchenko, TA, Vedunova, MV, Fimognari, C, Bachert, C, Coppieters, F, Lefever, S, Skirtach, AG, Krysko, O, Krysko, DV. Vaccination with early ferroptotic cancer cells induces efficient antitumor immunity J Immunother Cancer 8, e001369, 2020. (Epub 2020 Nov 13)
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El-Sherbiny, YM, Md Yusof, MY, Psarras, A, Hensor, EMA, Kabba, KZ, Dutton, K, Mohamed, AAA, Elewaut, D, McGonagle, D, Tooze, R, Doody, G, Wittmann, M, Emery, P, Vital, EM. B cell tetherin: a flow-cytometric cell-specific assay for response to Type-I interferon predicts clinical features and flares in SLE Arthritis Rheumatol 72, 769-779, 2020. (Epub 2019 Dec 5)
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Ferrada, L, Barahona, MJ, Salazar, K, Vandenabeele, P, Nualart, F. Vitamin C controls neuronal necroptosis under oxidative stress Redox Biol 29, 101408, 2020. (Epub 2019 Dec 16)
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Fraire, JC, Houthaeve, G, Liu, J, Raes, L, Vermeulen, L, Stremersch, S, Brans, T, Garcia-Diaz Barriga, G, De Keulenaer, S, Van Nieuwerburgh, F, De Rycke, R, Vandesompele, J, Mestdagh, P, Raemdonck, K, De Vos, WH, De Smedt, S, Braeckmans, K. Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis J Control Release 319, 262-275, 2020. (Epub 2020 Jan 2)
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Galluzzi, L, Vitale, I, Warren, S, Adjemian, S, Agostinis, P, Martinez, AB, Chan, TA, Coukos, G, Demaria, S, Deutsch, E, Draganov, D, Edelson, RL, Formenti, SC, Fucikova, J, Gabriele, L, Gaipl, US, Gameiro, SR, Garg, AD, Golden, E, et al.. Consensus guidelines for the definition, detection and interpretation of immunogenic cell death J Immunother Cancer 8, e000337, 2020. (Epub 2020 Mar 9)
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Gevaert, E, Delemarre, T, De Volder, J, Zhang, N, Holtappels, G, De Ruyck, N, Persson, E, Heyndrickx, I, Verstraete, K, Aegerter, H, Nauwynck, H, Savvides, SN, Lambrecht, BN, Bachert, C. Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis J Allergy Clin Immunol 145, 427-430, 2020. (Epub 2019 Sep 4)
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Gossec, L, Baraliakos, X, Kerschbaumer, A, de Wit, M, McInnes, I, Dougados, M, Primdahl, J, McGonagle, DG, Aletaha, D, Balanescu, A, Balint, PV, Bertheussen, H, Boehncke, WH, Burmester, GR, Canete, JD, Damjanov, NS, Kragstrup, TW, Kvien, TK, Landewe, RBM, et al.. EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update Ann Rheum Dis 79, 700-712, 2020. (Epub 2020 Jun)
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Govindarajan, S, Verheugen, E, Venken, K, Gaublomme, D, Maelegheer, M, Cloots, E, Gysens, F, De Geest, BG, Cheng, TY, Moody, DB, Janssens, S, Drennan, M, Elewaut, D. ER stress in antigen-presenting cells promotes NKT cell activation through endogenous neutral lipids EMBO Rep , e48927, 2020. (Epub 2020 May 3)
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Gracey, E, Burssens, A, Cambre, I, Schett, G, Lories, R, McInnes, IB, Asahara, H, Elewaut, D. Tendon and ligament mechanical loading in the pathogenesis of inflammatory arthritis Nat Rev Rheumatol 16, 193–207, 2020. (Epub 2020 Feb 20)
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Gracey, E, Vereecke, L, McGovern, D, Frohling, M, Schett, G, Danese, S, De Vos, M, Van den Bosch, F, Elewaut, D. Revisiting the gut-joint axis: links between gut inflammation and spondyloarthritis Nat Rev Rheumatol 16, 415-433, 2020. (Epub 2020 Jul 13)
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Grey, MJ, Cloots, E, Simpson, MS, LeDuc, N, Serebrenik, YV, De Luca, H, De Sutter, D, Luong, P, Thiagarajah, JR, Paton, AW, Paton, JC, Seeliger, MA, Eyckerman, S, Janssens, S, Lencer, WI. IRE1beta negatively regulates IRE1alpha signaling in response to endoplasmic reticulum stress J Cell Biol 219, e201904048, 2020. (Epub 2020 Feb 3)
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Grigoryan, R, Costas-Rodriguez, M, Vandenbroucke, RE, Vanhaecke, F. High-precision isotopic analysis of Mg and Ca in biological samples using multi-collector ICP-mass spectrometry after their sequential chromatographic isolation - Application to the characterization of the body distribution of Mg and Ca isotopes in mice Anal Chim Acta 1130, 137-145, 2020. (Epub 2020 Jul 28)
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Grootaert, H, Van Landuyt, L, Hulpiau, P, Callewaert, N. Functional exploration of the GH29 fucosidase family Glycobiology 30, 735-745, 2020. (Epub 2020 Aug 20)
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Guilliams, M, Thierry, GR, Bonnardel, J, Bajenoff, M. Establishment and Maintenance of the Macrophage Niche Immunity 52, 434-451, 2020. (Epub 2020 Mar 17)
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Hammad, H, Lambrecht, BN. Rbm7 in Structural Cells: A NEAT Way to Control Fibrosis Immunity 52, 429-431, 2020. (Epub 2020 Mar 17)
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Hammad, H, Lambrecht, BN. Wnt and Hippo pathways in regulatory T cells: a NOTCH above in asthma Nat Immunol 21, 1313–1314, 2020. (Epub 2020 Sep 23)
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Hassannia, B, Logie, E, Vandenabeele, P, Vanden Berghe, T, Vanden Berghe, W. Withaferin A: from Ayurvedic folk medicine to preclinical anti-cancer drug Biochem Pharmacol 173, 113602, 2020. (Epub 2019 Aug 9)
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Hassannia, B, Van Coillie, S, Vanden Berghe, T. Ferroptosis: biological rust of lipid membranes Antioxid Redox Signal , in press, 2020. (Epub 2020 Aug 18)
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Hastir, JF, Delbauve, S, Larbanoix, L, Germanova, D, Goyvaerts, C, Allard, J, Laurent, S, Breckpot, K, Beschin, A, Guilliams, M, Flamand, V. Hepatocarcinoma Induces a Tumor Necrosis Factor-Dependent Kupffer Cell Death Pathway That Favors Its Proliferation Upon Partial Hepatectomy Front Oncol 10, 547013, 2020. (Epub 2020 Oct 16)
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Hebeisen, M, Micheroli, R, Scherer, A, Baraliakos, X, de Hooge, M, van der Heijde, D, Landewe, R, Burki, K, Nissen, MJ, Moller, B, Zufferey, P, Exer, P, Ciurea, A. Spinal radiographic progression in axial spondyloarthritis and the impact of classification as nonradiographic versus radiographic disease: Data from the Swiss Clinical Quality Management cohort PLoS One 15, e0230268, 2020. (Epub 2020 Mar 20)
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Holgado, A, Braun, H, Verstraete, K, Vanneste, D, Callewaert, N, Savvides, SN, Afonina, IS, Beyaert, R. Single-Chain Soluble Receptor Fusion Proteins as Versatile Cytokine Inhibitors Front Immunol 11, 1422, 2020. (Epub 2020 Jul 13)
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Hulstaert, E, Morlion, A, Avila Cobos, F, Verniers, K, Nuytens, J, Vanden Eynde, E, Yigit, N, Anckaert, J, Geerts, A, Hindryckx, P, Jacques, P, Brusselle, G, Bracke, KR, Maes, T, Malfait, T, Derveaux, T, Ninclaus, V, Van Cauwenbergh, C, Roelens, K, et al.. Charting Extracellular Transcriptomes in The Human Biofluid RNA Atlas Cell Rep 33, 108552, 2020. (Epub 2020 Dec 29)
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Huyghe, L, Van Parys, A, Cauwels, A, Van Lint, S, De Munter, S, Bultinck, J, Zabeau, L, Hostens, J, Goethals, A, Vanderroost, N, Verhee, A, Uze, G, Kley, N, Peelman, F, Vandekerckhove, B, Brouckaert, P, Tavernier, J. Safe eradication of large established tumors using neovasculature-targeted tumor necrosis factor-based therapies EMBO Mol Med 12, e11223, 2020. (Epub 2020 Jan 8)
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Immunological Genome Project ImmGen at 15 Nat Immunol 21, 700-703, 2020. (Epub 2020 Jun 23)
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Jacobs, W, Lammens, M, Kerckhofs, A, Voets, E, Van San, E, Van Coillie, S, Peleman, C, Mergeay, M, Sirimsi, S, Matheeussen, V, Jansens, H, Baar, I, Vanden Berghe, T, Jorens, PG. Fatal lymphocytic cardiac damage in coronavirus disease 2019 (COVID-19): autopsy reveals a ferroptosis signature ESC Heart Fail 10, 1279-1287, 2020. (Epub 2020 Sep 22)
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Jangra, S, De Vrieze, J, Choi, A, Rathnasinghe, R, Laghlali, G, Uvyn, A, Van Herck, S, Nuhn, L, Deswarte, K, Zhong, Z, Sanders, N, Lienenklaus, S, David, S, Strohmeier, S, Amanat, F, Krammer, F, Hammad, H, Lambrecht, BN, Coughlan, L, et al.. Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Modified Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine bioRxiv , , 2020. (Epub 2020 Oct 23)
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Jian, Y, Merceron, R, De Munck, S, Forbes, HE, Hulpia, F, Risseeuw, MDP, Van Hecke, K, Savvides, SN, Munier-Lehmann, H, Boshoff, HIM, Van Calenbergh, S. Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents Eur J Med Chem 206, 112659, 2020. (Epub 2020 Jul 24)
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Kerr, SC, Gonzalez, JR, Schanin, J, Peters, MC, Lambrecht, BN, Brock, EC, Charbit, A, Ansel, KM, Youngblood, BA, Fahy, JV. An Anti-Siglec-8 Antibody Depletes Sputum Eosinophils from Asthmatic Subjects and Inhibits Lung Mast Cells Clin Exp Allergy 50, 904-914, 2020. (Epub 2020 Jun 15)
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Kerstens, W, Kremer, A, Holtappels, M, Borghgraef, P, Lippens, S, Van Dijck, P. Three-Dimensional Visualization of APEX2-Tagged Erg11 in Saccharomyces cerevisiae Using Focused Ion Beam Scanning Electron Microscopy mSphere 5, e00981-19, 2020. (Epub 2020 Feb 5)
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Kiltz, U, Landewe, RBM, van der Heijde, D, Rudwaleit, M, Weisman, MH, Akkoc, N, Boonen, A, Brandt, J, Carron, P, Dougados, M, Gossec, L, Jongkees, M, Machado, PM, Marzo-Ortega, H, Molto, A, Navarro-Compan, V, Niederman, K, Sampaio-Barros, PD, Slobodin, G, et al.. Development of ASAS quality standards to improve the quality of health and care services for patients with axial spondyloarthritis Ann Rheum Dis 79, 193-201, 2020. (Epub 2019 Oct 11)
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Kiltz, U, Wei, JC, van der Heijde, D, van den Bosch, F, Walsh, JA, Boonen, A, Gensler, LS, Hunter, T, Carlier, H, Dong, Y, Li, X, Bolce, R, Strand, V, Braun, J. Ixekizumab Improves Functioning and Health in the Treatment of Radiographic Axial Spondyloarthritis: Week 52 Results from 2 pivotal studies J Rheumatol 48, 188-197, 2020. (Epub 2020 Jul 15)
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Kim, S.W, Goossens, A, Libert, C, Van Immerseel, F, Staal, J, Beyaert, R. Phytohormones: Multifunctional nutraceuticals against metabolic syndrome and comorbid diseases Biochem Pharmacol 175, 113866, 2020. (Epub 2020 Feb 20)
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Kiss, M, Caro, AA, Raes, G, Laoui, D. Systemic Reprogramming of Monocytes in Cancer Front Oncol 10, 1399, 2020. (Epub 2020 Sep 17)
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Koudstaal, T, van Hulst, JAC, Das, T, Neys, SFH, Merkus, D, Bergen, IM, de Raaf, MA, Bogaard, HJ, Boon, L, van Loo, G, Aerts, J, Boomars, KA, Kool, M, Hendriks, RW. DNGR1-Cre-mediated Deletion of Tnfaip3/A20 in Conventional Dendritic Cells Induces Pulmonary Hypertension in Mice Am J Respir Cell Mol Biol 63, 665-680, 2020. (Epub 2020 Aug 5)
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Kozak, S, Bloch, Y, De Munck, S, Mikula, A, Bento, I, Savvides, SN, Meijers, R. Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis Acta Crystallogr D Struct Biol 76, 1244-1255, 2020. (Epub 2020 Dec 1)
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Kremer, A, Van Hamme, E, Bonnardel, J, Borghgraef, P, Guérin, C, Guilliams, M, Lippens, S. A workflow for 3D-CLEM investigating liver tissue J Microsc 281, 231-242, 2020. (Epub 2020 Oct 9)
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Landewe, RB, van der Heijde, D, Dougados, M, Baraliakos, X, Van den Bosch, FE, Gaffney, K, Bauer, L, Hoepken, B, Davies, OR, de Peyrecave, N, Thomas, K, Gensler, L. Maintenance of clinical remission in early axial spondyloarthritis following certolizumab pegol dose reduction Ann Rheum Dis 79, 920-928, 2020. (Epub 2020 May 7)
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Landewe, R, van der Heijde, D, Dougados, M, Baraliakos, X, Van den Bosch, F, Gaffney, K, Bauer, L, Hoepken, B, de Peyrecave, N, Thomas, K, Gensler, LS. Induction of Sustained Clinical Remission in Early Axial Spondyloarthritis Following Certolizumab Pegol Treatment: 48-Week Outcomes from C-OPTIMISE Rheumatol Ther 7, 581-599, 2020. (Epub 2020 Jun 11)
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Laukens, B, Jacobs, PP, Geysens, K, Martins, J, De Wachter, C, Ameloot, P, Morelle, W, Haustraete, J, Renauld, JC, Samyn, B, Contreras, R, Devos, S, Callewaert, N. Off-target glycans encountered along the synthetic biology route towards humanized N-glycans in Pichia pastoris Biotechnol Bioeng 117, 2479-2488, 2020. (Epub 2020 May 6)
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Laurien, L, Nagata, M, Schunke, H, Delanghe, T, Wiederstein, JL, Kumari, S, Schwarzer, R, Corona, T, Kruger, M, Bertrand, MJM, Kondylis, V, Pasparakis, M. Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation Nat Commun 11, 1747, 2020. (Epub 2020 Apr 8)
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Lavaert, M, Liang, KL, Vandamme, N, Park, JE, Roels, J, Kowalczyk, MS, Li, B, Ashenberg, O, Tabaka, M, Dionne, D, Tickle, TL, Slyper, M, Rozenblatt-Rosen, O, Vandekerckhove, B, Leclercq, G, Regev, A, Van Vlierberghe, P, Guilliams, M, Teichmann, SA, et al.. Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes Immunity 52, 1088-1104, 2020. (Epub 2020 Apr 13)
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Lebegge, E, Arnouk, SM, Bardet, PMR, Kiss, M, Raes, G, Van Ginderachter, JA. Innate Immune Defense Mechanisms by Myeloid Cells That Hamper Cancer Immunotherapy Front Immunol 11, 1395, 2020. (Epub 2020 Jul 09)
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Lefevere, E, Salinas-Navarro, M, Andries, L, Noterdaeme, L, Etienne, I, Van Wonterghem, E, Vinckier, S, Davis, BM, Van Bergen, T, Van Hove, I, Movahedi, K, Vandenbroucke, RE, Moons, L, De Groef, L. Tightening the retinal glia limitans attenuates neuroinflammation after optic nerve injury Glia 68, 2643-2660, 2020. (Epub 2020 Jul 9)
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