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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Van Coillie, S, Van San, E, Goetschalckx, I, Wiernicki, B, Mukhopadhyay, B, Tonnus, W, Choi, SM, Roelandt, R, Dumitrascu, C, Lamberts, L, Dams, G, Weyts, W, Huysentruyt, J, Hassannia, B, Ingold, I, Lele, S, Meyer, E, Berg, M, Seurinck, R, et al.. Targeting ferroptosis protects against experimental (multi)organ dysfunction and death Nat Commun 13, 1046, 2022. (Epub 2022 Feb 24) 
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Vandaele, R, Kang, B, De Bie, T, Saeys, Y. The Curse Revisited: When are Distances Informative for the Ground Truth in Noisy High-Dimensional Data? International Conference on Artificial Intelligence and Statistics, Vol 151 151, 2158-2172, 2022. (Epub 2022 May 3) 
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Van den Bosch, F, Wei, JC, Nash, P, Blanco, FJ, Graham, D, Zang, C, Arthur, E, Borlenghi, C, Tsekouras, V, Vlahos, B, Deodhar, A. Etanercept Withdrawal and Re-Treatment in Non-Radiographic Axial Spondyloarthritis: Results of RE-EMBARK, an Open-Label, Phase IV Trial J Rheumatol , in press, 2022. (Epub 2022 Nov 15)
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Vandendriessche, C, Kapogiannis, D, Vandenbroucke, RE. Biomarker and therapeutic potential of peripheral extracellular vesicles in Alzheimer's disease Adv Drug Deliv Rev , 114486, 2022. (Epub 2022 Aug 8)
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Vanderhaeghen, T, Timmermans, S, Watts, D, Paakinaho, V, Eggermont, M, Vandewalle, J, Wallaeys, C, Van Wyngene, L, Van Looveren, K, Nuyttens, L, Dewaele, S, Vanden Berghe, J, Lemeire, K, De Backer, J, Dirkx, L, Vanden Berghe, W, Caljon, G, Ghesquiere, B, De Bosscher, K, et al.. Reprogramming of glucocorticoid receptor function by hypoxia EMBO Rep 23, e53083, 2022. (Epub 2021 Oct 26)
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van der Heijde, D, Deodhar, A, Maksymowych, WP, Sieper, J, Van den Bosch, F, Kim, TH, Kishimoto, M, Ostor, AJ, Combe, B, Sui, Y, Duan, Y, Wung, PK, Song, IH. Upadacitinib in active ankylosing spondylitis: results of the 2-year, double-blind, placebo-controlled SELECT-AXIS 1 study and open-label extension RMD Open 8, e002280, 2022. (Epub 2022 Jul 27)
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Van de Sompele, S, Small, KW, Cicekdal, MB, Soriano, VL, D'Haene, E, Shaya, FS, Agemy, S, Van der Snickt, T, Rey, AD, Rosseel, T, Van Heetvelde, M, Vergult, S, Balikova, I, Bergen, AA, Boon, CJF, De Zaeytijd, J, Inglehearn, CF, Kousal, B, Leroy, BP, et al.. Multi-omics approach dissects cis-regulatory mechanisms underlying North Carolina macular dystrophy, a retinal enhanceropathy Am J Hum Genet 109, 2029-2048, 2022. (Epub 2022 Nov 3)
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Vandewalle, J, Garcia, B, Timmermans, S, Vanderhaeghen, T, Van Wyngene, L, Eggermont, M, Dufoor, H, Van Dender, C, Halimi, F, Croubels, S, Herpain, A, Libert, C. Hepatic Peroxisome Proliferator-Activated Receptor Alpha Dysfunction in Porcine Septic Shock Cells 11, 4080, 2022. (Epub 2022 Dec 16)
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Vandewalle, J, Libert, C. Sepsis: a failing starvation response Trends Endocrinol Metab 33, 292-304, 2022. (Epub 2022 Feb 15)
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Van Ginderachter, JA. The Heat Is On: 20-HETE Instructs an Immunosuppressive Phenotype in Cancer-Associated Fibroblasts Cancer Res 82, 3882-3883, 2022. (Epub 2022 Nov 2)
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Van Hauwermeiren, F, Van Opdenbosch, N, Van Gorp, H, de Vasconcelos, N, van Loo, G, Vandenabeele, P, Kanneganti, TD, Lamkanfi, M. Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax Proc Natl Acad Sci U S A 119, e2116415119, 2022. (Epub 2022 Jan 11)
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Van Hoovels, L, Studholme, L, Vander Cruyssen, B, Sieghart, D, Bonroy, C, Nagy, E, Pullerits, R, Cucnik, S, Dahle, C, Heijnen, I, Bernasconi, L, Benkhadra, F, Bogaert, L, Van Den Bremt, S, Van Liedekerke, A, Vanheule, G, Robbrecht, J, Wirth, C, Muller, R, et al.. Standardisation of ACPA tests: evaluation of a new candidate reference preparation Ann Rheum Dis 81, 1379-1384, 2022. (Epub 2022 Jun 13)
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Van Hoovels, L, Vander Cruyssen, B, Sieghart, D, Bonroy, C, Nagy, E, Pullerits, R, Cucnik, S, Dahle, C, Heijnen, I, Bernasconi, L, Benkhadra, F, Bogaert, L, Van Den Bremt, S, Van Liedekerke, A, Vanheule, G, Robbrecht, J, Studholme, L, Wirth, C, Muller, R, et al.. IgA rheumatoid factor in rheumatoid arthritis Clin Chem Lab Med 60, 1617-1626, 2022. (Epub 2022 Jul 6)
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Van Hoovels, L, Vander Cruyssen, B, Sieghart, D, Bonroy, C, Nagy, E, Pullerits, R, Cucnik, S, Dahle, C, Heijnen, I, Bernasconi, L, Benkhadra, F, Bogaert, L, Van Den Bremt, S, Van Liedekerke, A, Vanheule, G, Robbrecht, J, Studholme, L, Wirth, C, Muller, R, et al.. Multicentre study to improve clinical interpretation of rheumatoid factor and anti-citrullinated protein/peptide antibodies test results RMD Open 8, e002099, 2022. (Epub 2022 Mar)
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Van Hove, L, Hoste, E. Activation of Fibroblasts in Skin Cancer J Invest Dermatol 142, 1026-1031, 2022. (Epub 2021 Sep 30)
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van Loo, G, Bertrand, MJM. Death by TNF: a road to inflammation Nat Rev Immunol , in press, 2022. (Epub 2022 Nov 15)
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Vanmeerbeek, I, Govaerts, J, Laureano, RS, Sprooten, J, Naulaerts, S, Borras, DM, Laoui, D, Mazzone, M, Van Ginderachter, JA, Garg, AD. The Interface of Tumour-Associated Macrophages with Dying Cancer Cells in Immuno-Oncology Cells 11, 3890, 2022. (Epub 2022 Dec 2)
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Van Moortel, L, Thommis, J, Maertens, B, Staes, A, Clarisse, D, De Sutter, D, Libert, C, Meijer, OC, Eyckerman, S, Gevaert, K, De Bosscher, K. Novel assays monitoring direct glucocorticoid receptor protein activity exhibit high predictive power for ligand activity on endogenous gene targets Biomed Pharmacother 152, 113218, 2022. (Epub 2022 Jun 13)
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Vanneste, D, Staal, J, Haegman, M, Driege, Y, Carels, M, Van Nuffel, E, De Bleser, P, Saeys, Y, Beyaert, R, Afonina, IS. CARD14 Signalling Ensures Cell Survival and Cancer Associated Gene Expression in Prostate Cancer Cells Biomedicines 10, 2008, 2022. (Epub 2022 Aug 18)
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Van Nevel, S, Declercq, J, Holtappels, G, Lambrecht, BN, Bachert, C. Granulocyte-colony stimulating factor: Missing link for stratification of type 2-high and type 2-low chronic rhinosinusitis patients J Allergy Clin Immunol 149, 1655-1665, 2022. (Epub 2022 Mar 9)
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Van Royen, T, Sedeyn, K, Moschonas, GD, Toussaint, W, Vuylsteke, M, Van Haver, D, Impens, F, Eyckerman, S, Lemmens, I, Tavernier, J, Schepens, B, Saelens, X. An Unexpected Encounter: Respiratory Syncytial Virus Nonstructural Protein 1 Interacts with Mediator Subunit MED25 J Virol 96, e0129722, 2022. (Epub 2022 Sep 14)
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Van Wonterghem, E, Van Hoecke, L, Van Imschoot, G, Verhaege, D, Burgelman, M, Vandenbroucke, RE. Microdissection and Whole Mount Scanning Electron Microscopy Visualization of Mouse Choroid Plexus J Vis Exp , 190, 2022. (Epub 2022 Dec 16)
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Varasteh, Z, Braeuer, M, Mohanta, S, Steinsiek, AL, Habenicht, A, Omidvari, N, Topping, GJ, Rischpler, C, Weber, WA, Sager, HB, Raes, G, Hernot, S, Schwaiger, M. In vivo Visualization of M2 Macrophages in the Myocardium After Myocardial Infarction (MI) Using (68) Ga-NOTA-Anti-MMR Nb: Targeting Mannose Receptor (MR, CD206) on M2 Macrophages Front Cardiovasc Med 9, 889963, 2022. (Epub 2022 Apr 25)
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Vecchia, MD, Conte-Daban, A, Cappe, B, Vandenberg, W, Vandenabeele, P, Riquet, FB, Dedecker, P. Spectrally Tunable Forster Resonance Energy Transfer-Based Biosensors Using Organic Dye Grafting ACS Sens 7, 2920-2927, 2022. (Epub 2022 Oct 28)
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Verdonck, S, Nemegeer, J, Vandenabeele, P, Maelfait, J. Viral manipulation of host cell necroptosis and pyroptosis Trends Microbiol 30, 593-605, 2022. (Epub 2021 Dec 18)
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Verheye, E, Bravo Melgar, J, Deschoemaeker, S, Raes, G, Maes, A, De Bruyne, E, Menu, E, Vanderkerken, K, Laoui, D, De Veirman, K. Dendritic Cell-Based Immunotherapy in Multiple Myeloma: Challenges, Opportunities, and Future Directions Int J Mol Sci 23, 904, 2022. (Epub 2022 Jan 14)
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Vermeirssen, V, Deleu, J, Morlion, A, Everaert, C, De Wilde, J, Anckaert, J, Durinck, K, Nuytens, J, Rishfi, M, Speleman, F, Van Droogenbroeck, H, Verniers, K, Baietti, MF, Albersen, M, Leucci, E, Post, E, Best, MG, Van Maerken, T, De Wilde, B, et al.. Whole transcriptome profiling of liquid biopsies from tumour xenografted mouse models enables specific monitoring of tumour-derived extracellular RNA NAR Cancer 4, zcac037, 2022. (Epub 2022 Nov 28)
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Villar, VH, Allega, MF, Deshmukh, R, Ackermann, T, Nakasone, MA, Vande Voorde, J, Drake, TM, Oetjen, J, Bloom, A, Nixon, C, Muller, M, May, S, Tan, EH, Vereecke, L, Jans, M, Blancke, G, Murphy, DJ, Huang, DT, Lewis, DY, et al.. Hepatic glutamine synthetase controls N(5)-methylglutamine in homeostasis and cancer Nat Chem Biol , in press, 2022. (Epub 2022 Oct 24)
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Waller, K, Scott, CL. Who on IRF are you? IRF8 deficiency redirects cDC1 lineage commitment Trends Immunol 43, 687-689, 2022. (Epub 2022 Aug 10)
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Weinhaupl, K, Gragera, M, Bueno-Carrasco, MT, Arranz, R, Krandor, O, Akopian, T, Soares, R, Rubin, E, Felix, J, Fraga, H. Structure of the drug target ClpC1 unfoldase in action provides insights on antibiotic mechanism of action J Biol Chem 298, 102553, 2022. (Epub 2022 Oct 6)
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Whyte, CE, Singh, K, Burton, OT, Aloulou, M, Kouser, L, Veiga, RV, Dashwood, A, Okkenhaug, H, Benadda, S, Moudra, A, Bricard, O, Lienart, S, Bielefeld, P, Roca, CP, Naranjo-Galindo, FJ, Lombard-Vadnais, F, Junius, S, Bending, D, Ono, MM, et al.. Context-dependent effects of IL-2 rewire immunity into distinct cellular circuits J Exp Med 219, e20212391, 2022. (Epub 2022 Jul 4)
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Wiernicki, B, Maschalidi, S, Pinney, J, Adjemian, S, Vanden Berghe, T, Ravichandran, KS, Vandenabeele, P. Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity Nat Commun 13, 3676, 2022. (Epub 2022 Jun 27)
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Wynendaele, E, Debunne, N, Janssens, Y, De Spiegeleer, A, Verbeke, F, Tack, L, Van Welden, S, Goossens, E, Knappe, D, Hoffmann, R, Van De Wiele, C, Laukens, D, Van Eenoo, P, Vereecke, L, Van Immerseel, F, De Wever, O, De Spiegeleer, B. The quorum sensing peptide EntF* promotes colorectal cancer metastasis in mice: a new factor in the host-microbiome interaction BMC Biol 20, 151, 2022. (Epub 2022 Jun 27)
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Xiao, P, Takiishi, T, Violato, NM, Licata, G, Dotta, F, Sebastiani, G, Marselli, L, Singh, SP, Sze, M, Van Loo, G, Dejardin, E, Gurzov, EN, Cardozo, AK. NF-kappaB-inducing kinase (NIK) is activated in pancreatic beta-cells but does not contribute to the development of diabetes Cell Death Dis 13, 476, 2022. (Epub 2022 May 19)
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Xie, J, Li, Q, Haesebrouck, F, Van Hoecke, L, Vandenbroucke, RE. The tremendous biomedical potential of bacterial extracellular vesicles Trends Biotechnol 40, 1173-1194, 2022. (Epub 2022 May 14)
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Xie, J, Van Hoecke, L, Vandenbroucke, RE. The Impact of Systemic Inflammation on Alzheimer's Disease Pathology Front Immunol 12, 796867, 2022. (Epub 2022 Jan 6)
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Yshii, L, Pasciuto, E, Bielefeld, P, Mascali, L, Lemaitre, P, Marino, M, Dooley, J, Kouser, L, Verschoren, S, Lagou, V, Kemps, H, Gervois, P, de Boer, A, Burton, OT, Wahis, J, Verhaert, J, Tareen, SHK, Roca, CP, Singh, K, et al.. Astrocyte-targeted gene delivery of interleukin 2 specifically increases brain-resident regulatory T cell numbers and protects against pathological neuroinflammation Nat Immunol 23, 878-891, 2022. (Epub 2022 May 26)
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Zheng, F, Pang, Y, Li, L, Pang, Y, Zhang, J, Wang, X, Raes, G. Applications of nanobodies in brain diseases Front Immunol 13, 978513, 2022. (Epub 2022 Nov 8)
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Aaes, TL, Vandenabeele, P. The intrinsic immunogenic properties of cancer cell lines, immunogenic cell death, and how these influence host antitumor immune responses Cell Death Differ 28, 843-860, 2021. (Epub 2020 Nov 19)
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Ackaert, C, Smiejkowska, N, Xavier, C, Sterckx, YGJ, Denies, S, Stijlemans, B, Elkrim, Y, Devoogdt, N, Caveliers, V, Lahoutte, T, Muyldermans, S, Breckpot, K, Keyaerts, M. Immunogenicity Risk Profile of Nanobodies Front Immunol 12, 632687, 2021. (Epub 2021 Mar 9)
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Ackermann, M, Anders, HJ, Bilyy, R, Bowlin, GL, Daniel, C, De Lorenzo, R, Egeblad, M, Henneck, T, Hidalgo, A, Hoffmann, M, Hohberger, B, Kanthi, Y, Kaplan, MJ, Knight, JS, Knopf, J, Kolaczkowska, E, Kubes, P, Leppkes, M, Mahajan, A, et al.. Patients with COVID-19: in the dark-NETs of neutrophils Cell Death Differ 28, 3125-3139, 2021. (Epub 2021 May 24)
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Adami, V, Homer, N, Utz, N, Lippens, S, Rappoport, JZ, Fernandez-Rodriguez, J. An international survey of Training Needs and Career Paths of Core Facility Staff J Biomol Tech 32, 1-9, 2021. (Epub 2020 Nov 20)
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Aegerter, H, Smole, U, Heyndrickx, I, Verstraete, K, Savvides, SN, Hammad, H, Lambrecht, BN. Charcot-Leyden crystals and other protein crystals driving type 2 immunity and allergy Curr Opin Immunol 72, 104-110, 2021. (Epub 2021 Apr 16)
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Afonina, IS, Van Nuffel, E, Beyaert, R. Immune responses and therapeutic options in psoriasis Cell Mol Life Sci 78, 2709–2727, 2021. (Epub 2021 Jan 2)
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Aguilera-Lizarraga, J, Florens, MV, Viola, MF, Jain, P, Decraecker, L, Appeltans, I, Cuende-Estevez, M, Fabre, N, Van Beek, K, Perna, E, Balemans, D, Stakenborg, N, Theofanous, S, Bosmans, G, Mondelaers, SU, Matteoli, G, Ibiza Martinez, S, Lopez-Lopez, C, Jaramillo-Polanco, J, et al.. Local immune response to food antigens drives meal-induced abdominal pain Nature 590, 151-156, 2021. (Epub 2021 Jan 13)
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Alexander, SP, Fabbro, D, Kelly, E, Mathie, A, Peters, JA, Veale, EL, Armstrong, JF, Faccenda, E, Harding, SD, Pawson, AJ, Southan, C, Davies, JA, Beuve, A, Brouckaert, P, Bryant, C, Burnett, JC, Farndale, RW, Friebe, A, Garthwaite, J, et al.. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors Br J Pharmacol 178, S264-S312, 2021. (Epub 2021 Sep 17)
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Almeida, L, Dhillon-LaBrooy, A, Castro, CN, Adossa, N, Carriche, GM, Guderian, M, Lippens, S, Dennerlein, S, Hesse, C, Lambrecht, BN, Berod, L, Schauser, L, Blazar, BR, Kalesse, M, Muller, R, Moita, LF, Sparwasser, T. Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis Immunity 54, 68-83, 2021. (Epub 2020 Nov 24)
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Anderson, CJ, Medina, CB, Barron, BJ, Karvelyte, L, Aaes, TL, Lambertz, I, Perry, JSA, Mehrotra, P, Goncalves, A, Lemeire, K, Blancke, G, Andries, V, Ghazavi, F, Martens, A, van Loo, G, Vereecke, L, Vandenabeele, P, Ravichandran, KS. Microbes exploit death-induced nutrient release by gut epithelial cells Nature 596, 262-267, 2021. (Epub 2021 Aug 4)
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Andries, L, Masin, L, Navarro, MS, Zaunz, S, Claes, M, Bergmans, S, Brouwers, V, Lefevere, E, Verfaillie, C, Movahedi, K, De Groef, L, Moons, L. MMP2 Modulates Inflammatory Response during Axonal Regeneration in the Murine Visual System Cells 10, 1672, 2021. (Epub 2021 Jul 2)
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Arandjelovic, S, Perry, JSA, Zhou, M, Ceroi, A, Smirnov, I, Walk, SF, Shankman, LS, Cambre, I, Onengut-Gumuscu, S, Elewaut, D, Conrads, TP, Ravichandran, KS. ELMO1 signaling is a promoter of osteoclast function and bone loss Nat Commun 12, 4974, 2021. (Epub 2021 Aug 17)
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