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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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McFarlane, SM, Pashmi, G, Connell, MC, Littlejohn, AF, Tucker, SJ, Vandenabeele, P, MacEwan, DJ. Differential activation of nuclear factor-kB by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly FEBS Lett 515, 119-126, 2002. (Epub ---) 
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Müller, N, Reinacher-Schick, A, Baldus, S, van Hengel, J, Berx, G, Baar, A, van Roy, F, Schmiegel, W, Schwarte-Waldhoff, I. Smad4 induces the tumor suppressor E-cadherin and P-cadherin in colon carcinoma cells Oncogene 21, 6049-6058, 2002. (Epub ---)
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Mohamed, AAA, Jupp, OJ, Anderson, HM, Littlejohn, AF, Vandenabeele, P, MacEwan, DJ. Tumour necrosis factor-induced activation of c-Jun N-terminal kinase is sensitive to caspase-dependent modulation while activation of mitogen-activated protein kinase (MAPK) or p38 MAPK is not Biochem J 366, 145-155, 2002. (Epub ---)
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Pollock, J, McFarlane, SM, Connell, MC, Zehavi, U, Vandenabeele, P, MacEwan, DJ, Scott, RH. TNF-a receptors simultaneously activate Ca2+ mobilisation and stress kinases in cultured sensory neurones Neuropharmacology 42, 93-106, 2002. (Epub ---)
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Reeves, PJ, Callewaert, N, Contreras, R, Khorana, HG. Structure and function in rhodopsin: High-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line Proc Natl Acad Sci USA 99, 13419-13424, 2002. (Epub 2002 Oct 7)
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Rendl, M, Ban, J, Mrass, P, Mayer, C, Lengauer, B, Eckhart, L, Declercq, W, Tschachler, E. Caspase-14 expression by epidermal keratinocytes is regulated by retinoids in a differentiation-associated manner J Invest Dermatol 119, 1150-1155, 2002. (Epub ---)
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Schauvliege, R, Vanrobaeys, J, Schotte, P, Beyaert, R. Caspase-11 gene expression in response to lipopolysaccharide and interferon-gamma requires nuclear factor-kB and signal transducer and activator of transcription (STAT) 1 J Biol Chem 277, 41624–41630, 2002. (Epub 2002 Aug 26)
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Staelens, J, Wielockx, B, Puimège, L, Van Roy, F, Guénet, J-L, Libert, C. Hyporesponsiveness of SPRET/Ei mice to lethal shock induced by tumor necrosis factor and implications for a TNF-based antitumor therapy Proc Natl Acad Sci USA 99, 9340-9345, 2002. (Epub 2002 Jun 27)
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Steidler, L. In situ delivery of cytokines by genetically engineered Lactococcus lactis Antonie van Leeuwenhoek 82, 323-331, 2002. (Epub ---)
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Storey, H, Stewart, A, Vandenabeele, P, Luzio, JP. The p55 tumour necrosis factor receptor TNFR1 contains a trans-Golgi network localization signal in the C-terminal region of its cytoplasmic tail Biochem J 366, 15-22, 2002. (Epub ---)
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Vanden Berghe, W, De Bosscher, K, Vermeulen, L, De Wilde, G, Haegeman, G. Induction and repression of NF-kB-driven inflammatory genes In Recent Advances in Glucocorticoid Receptor Action. (Cato, A, Schaecke, H, Asadullah, K, eds.), Ernst Schering Research Foundation Workshop, Vol. 40, Heidelberg, Springer, pp. 233-278, 2002. (Epub ---) 
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van der Werff ten Bosch, J, Schotte, P, Ferster, A, Azzi, N, Boehler, T, Laureys, G, Arola, M, Demanet, C, Beyaert, R, Thielemans, K, Otten, J. Reversion of autoimmune lymphoproliferative syndrome with an antimalarial drug: Preliminary results of a clinical cohort study and molecular observations Br J Haematol 117, 176-188, 2002. (Epub ---)
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Van Herreweghe, F, Mao, J, Chaplen, FWR, Grooten, J, Gevaert, K, Vandekerckhove, J, Vancompernolle, K. Tumor necrosis factor-induced modulation of glyoxalase I activities through phosphorylation by PKA results in cell death and is accompanied by the formation of a specific methylglyoxal-derived AGE Proc Natl Acad Sci USA 99, 949-954, 2002. (Epub 2002 Jan 15)
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van Loo, G, Demol, H, van Gurp, M, Hoorelbeke, B, Schotte, P, Beyaert, R, Zhivotovsky, B, Gevaert, K, Declercq, W, Vandekerckhove, J, Vandenabeele, P. A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid Cell Death Differ 9, 301-308, 2002. (Epub ---)
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van Loo, G, Saelens, X, Matthijssens, F, Schotte, P, Beyaert, R, Declercq, W, Vandenabeele, P. Caspases are not localized in mitochondria during life or death Cell Death Differ 9, 1207-1211, 2002. (Epub ---)
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van Loo, G, Saelens, X, van Gurp, M, MacFarlane, M, Martin, SJ, Vandenabeele, P. The role of mitochondrial factors in apoptosis: A Russian roulette with more than one bullet Cell Death Differ 9, 1031-1042, 2002. (Epub ---)
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van Loo, G, van Gurp, M, Depuydt, B, Srinivasula, SM, Rodriguez, I, Alnemri, ES, Gevaert, K, Vandekerckhove, J, Declercq, W, Vandenabeele, P. The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity Cell Death Differ 9, 20-26, 2002. (Epub ---)
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Van Molle, W, Wielockx, B, Mahieu, T, Takada, M, Taniguchi, T, Sekikawa, K, Libert, C. HSP70 protects against TNF-induced lethal inflammatory shock Immunity 16, 685-695, 2002. (Epub ---)
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Vanpoucke, G, Nollet, F, Tejpar, S, Cassiman, J-J, van Roy, F. The human alpha E-catenin gene CTNNA1: Mutational analysis and rare occurrence of a truncated splice variant Biochim Biophys Acta 1574, 262-268, 2002. (Epub ---)
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Van Roy, F. In search of sticky protocols (Book Review) Nat Cell Biol 4, E80, 2002. (Epub ---)
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Van Roy, N, Vandesompele, J, Berx, G, Staes, K, Van Gele, M, De Smet, E, De Paepe, A, Laureys, G, van der Drift, P, Versteeg, R, Van Roy, F, Speleman, F. Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type 1 patients Genes Chromosomes Cancer 35, 113-120, 2002. (Epub ---)
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Varghese, J, Sade, H, Vandenabeele, P, Sarin, A. Head involution defective (Hid)-triggered apoptosis requires caspase-8 but not FADD (Fas-associated death domain) and is regulated by Erk in mammalian cells J Biol Chem 277, 35097–35104, 2002. (Epub 2002 Jul 16)
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Vermeulen, L, De Wilde, G, Notebaert, S, Vanden Berghe, W, Haegeman, G. Regulation of the transcriptional activity of the nuclear factor-kB p65 subunit Biochem Pharmacol 64, 963-970, 2002. (Epub ---)
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Waelput, W, Brouckaert, P, Broekaert, D, Tavernier, J. A role for leptin in the systemic inflammatory response syndrome (SIRS) and in immune response Current Drug Targets Inflamm Allergy 1, 277-289, 2002. (Epub ---)
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Ameloot, P, Declercq, W, Fiers, W, Vandenabeele, P, Brouckaert, P. Heterotrimers formed by tumor necrosis factors of different species or muteins J Biol Chem 276, 27098-27103, 2001. (Epub 2001 May 22)
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Ameloot, P, Fiers, W, De Bleser, P, Ware, CF, Vandenabeele, P, Brouckaert, P. Identification of tumor necrosis factor (TNF) amino acids crucial for binding to the murine p75 TNF receptor and construction of receptor-selective mutants J Biol Chem 276, 37426-37430, 2001. (Epub 2001 Jul 11)
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Berx, G, Van Roy, F. The E-cadherin/catenin complex: An important gatekeeper in breast cancer tumorigenesis and malignant progression Breast Cancer Res 3, 289-293, 2001. (Epub 2001 Jun 28)
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Callewaert, N, Geysens, S, Molemans, F, Contreras, R. Ultrasensitive profiling and sequencing of N-linked oligosaccharides using standard DNA-sequencing equipment Glycobiology 11, 275-281, 2001. (Epub ---)
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Callewaert, N, Laroy, W, Cadirgi, H, Geysens, S, Saelens, X, Min Jou, W, Contreras, R. Use of HDEL-tagged Trichoderma reesei mannosyl oligosaccharide 1,2-a-D-mannosidase for N-glycan engineering in Pichia pastoris FEBS Lett 503, 173-178, 2001. (Epub ---)
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Clavel, CE, Nollet, F, Berx, G, Tejpar, S, Nawrocki-Raby, B, Kaplan, HH, Van Roy, FM, Birembaut, PL. Expression of the E-cadherin-catenin complex in lung neuroendocrine tumours J Pathol 194, 20-26, 2001. (Epub ---)
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Comijn, J, Berx, G, Vermassen, P, Verschueren, K, van Grunsven, L, Bruyneel, E, Mareel, M, Huylebroeck, D, van Roy, F. The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion Mol Cell 7, 1267-1278, 2001. (Epub ---)
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Daemen, MARC, Denecker, G, van 't Veer, C, Wolfs, TGAM, Vandenabeele, P, Buurman, WA. Activated caspase-1 is not a central mediator of inflammation in the course of ischemia-reperfusion Transplantation 71, 778-784, 2001. (Epub ---)
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De Backer, MD, Nelissen, B, Logghe, M, Viaene, J, Loonen, I, Vandoninck, S, de Hoogt, R, Dewaele, S, Simons, FA, Verhasselt, P, Vanhoof, G, Contreras, R, Luyten, WHML. An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans Nat Biotechnol 19, 235-241, 2001. (Epub ---)
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De Bosscher, K, Vanden Berghe, W, Haegeman, G. Glucocorticoid repression of AP-1 is not mediated by competition for nuclear coactivators Mol Endocrinol 15, 219-227, 2001. (Epub ---)
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Denecker, G, Declercq, W, Geuijen, CAW, Boland, A, Benabdillah, R, van Gurp, M, Sory, M-P, Vandenabeele, P, Cornelis, GR. Yersinia enterocolitica YopP-induced apoptosis of macrophages involves the apoptotic signaling cascade upstream of Bid J Biol Chem 276, 19706-19714, 2001. (Epub 2001 Mar 14)
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Denecker, G, Vercammen, D, Declercq, W, Vandenabeele, P. Apoptotic and necrotic cell death induced by death domain receptors Cell Mol Life Sci 58, 356-370, 2001. (Epub ---)
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Denecker, G, Vercammen, D, Steemans, M, Vanden Berghe, T, Brouckaert, G, van Loo, G, Zhivotovsky, B, Fiers, W, Grooten, J, Declercq, W, Vandenabeele, P. Death receptor-induced apoptotic and necrotic cell death: Differential role of caspases and mitochondria Cell Death Differ 8, 829-840, 2001. (Epub ---)
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De Wilde, G, Mertens, N, Boone, E, De Vreese, B, Van Beeumen, J, Fiers, W, Haegeman, G. Expression in Escherichia coli of the death domain of the human p55 tumor necrosis factor receptor Protein Expr Purif 23, 226–232, 2001. (Epub ---)
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De Wilde, G, Murray-Rust, J, Boone, E, Olerenshaw, D, McDonald, NQ, Ibanez, C, Haegeman, G, Wollmer, A, Federwisch, M. Structure-activity relationship of the p55 TNF receptor death domain and its lymphoproliferation mutants Eur J Biochem 268, 1382-1391, 2001. (Epub ---)
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Dick, JMC, Van Molle, W, Libert, C, Lefebvre, RA. Antisense knockdown of inducible nitric oxide synthase inhibits the relaxant effect of VIP in isolated smooth muscle cells of the mouse gastric fundus Br J Pharmacol 134, 425-433, 2001. (Epub ---)
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Evans, PC, Taylor, ER, Coadwell, J, Heyninck, K, Beyaert, R, Kilshaw, PJ. Isolation and characterization of two novel A20-like proteins Biochem J 357, 617-623, 2001. (Epub ---)
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Fiers, W, Neirynck, S, Deroo, T, Saelens, X, Min Jou, W. Soluble recombinant influenza vaccine Philos Trans R Soc Lond B Biol Sci 356, 1961-1963, 2001. (Epub ---)
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Frame, M, Wan, KF, Tate, R, Vandenabeele, P, Pyne, NJ. The g subunit of the rod photoreceptor cGMP phosphodiesterase can modulate the proteolysis of two cGMP binding cGMP-specific phosphodiesterases (PDE6 and PDE5) by caspase-3 Cell Signal 13, 735-741, 2001. (Epub ---)
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Heyninck, K, Beyaert, R. Crosstalk between NF-kB-activating and apoptosis-inducing proteins of the TNF-receptor complex Mol Cell Biol Res Commun 4, 259-265, 2001. (Epub ---)
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Janssens, B, Goossens, S, Staes, K, Gilbert, B, van Hengel, J, Colpaert, C, Bruyneel, E, Mareel, M, van Roy, F. alphaT-Catenin: A novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion J Cell Sci 114, 3177-3188, 2001. (Epub ---)
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Jupp, OJ, McFarlane, SM, Anderson, HM, Littlejohn, AF, Mohamed, AAA, MacKay, RH, Vandenabeele, P, MacEwan, DJ. Type II tumour necrosis factor-alpha receptor (TNFR2) activates c-Jun N-terminal kinase (JNK) but not mitogen-activated protein kinase (MAPK) or p38 MAPK pathways Biochem J 359, 525-535, 2001. (Epub ---)
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Klinkenberg, M, Van Huffel, S, Heyninck, K, Beyaert, R. Functional redundancy of the zinc fingers of A20 for inhibition of NF-kB activation and protein-protein interactions FEBS Lett 498, 93-97, 2001. (Epub ---)
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Kotelevets, L, van Hengel, J, Bruyneel, E, Mareel, M, van Roy, F, Chastre, E. The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness J Cell Biol 155, 1129-1135, 2001. (Epub 2001 Dec 24)
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Laroy, W, Ameloot, P, Contreras, R. Characterization of sialyltransferase mutants using surface plasmon resonance Glycobiology 11, 175-182, 2001. (Epub ---)
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Machado, JC, Oliveira, C, Carvalho, R, Soares, P, Berx, G, Caldas, C, Seruca, R, Carneiro, F, Sobrinho-Simões, M. E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma Oncogene 20, 1525-1528, 2001. (Epub ---)
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