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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Marti, A, Ritter, PM, Jäger, R, Lazar, H, Baltzer, A, Schenkel, J, Declercq, W, Vandenabeele, P, Jaggi, R. Mouse mammary gland involution is associated with cytochrome c release and caspase activation Mech Dev 104, 89-98, 2001. (Epub ---) 
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McFarlane, SM, Jupp, OJ, Cobban, HJ, Hunter, I, Anderson, HM, Vandenabeele, P, Nixon, GF, MacEwan, DJ. Stimulation of stress-activated but not mitogen-activated protein kinases by tumour necrosis factor receptor subtypes in airway smooth muscle Biochem Pharmacol 61, 749-759, 2001. (Epub ---)
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Mertens, N, Schoonjans, R, Willems, A, Schoonooghe, S, Leoen, J, Grooten, J. New recombinant bi- and trispecific antibody derivatives In Novel Frontiers in the Production of Compounds for Biomedical Use. (Van Broekhoven, A, Shapiro, F, Anné, J, eds.), Focus on Biotechnology, Vol. 1, Dordrecht, Kluwer Academic Publishers, pp. 195-208, 2001. (Epub ---) 
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Nawrocki Raby, B, Polette, M, Gilles, C, Clavel, C, Strumane, K, Matos, M, Zahm, J-M, Van Roy, F, Bonnet, N, Birembaut, P. Quantitative cell dispersion analysis: New test to measure tumor cell aggressiveness Int J Cancer 93, 644-652, 2001. (Epub ---)
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Saelens, X, Kalai, M, Vandenabeele, P. Translation inhibition in apoptosis. Caspase-dependent PKR activation and eIF2-a phosphorylation J Biol Chem 276, 41620-41628, 2001. (Epub 2001 Sep 12)
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Schoonjans, R, Willems, A, Schoonooghe, S, Leoen, J, Grooten, J, Mertens, N. A new model for intermediate molecular weight recombinant bispecific and trispecific antibodies by efficient heterodimerization of single chain variable domains through fusion to a Fab-chain Biomol Eng 17, 193-202, 2001. (Epub ---)
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Schotte, P, Schauvliege, R, Janssens, S, Beyaert, R. The cathepsin B inhibitor z-FA.fmk inhibits cytokine production in macrophages stimulated by lipopolysaccharide J Biol Chem 276, 21153-21157, 2001. (Epub 2001 Apr 4)
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Schotte, P, van Loo, G, Carpentier, I, Vandenabeele, P, Beyaert, R. Lithium sensitizes tumor cells in an NF-kB-independent way to caspase activation and apoptosis induced by tumor necrosis factor (TNF). Evidence for a role of the TNF receptor-associated death domain protein J Biol Chem 276, 25939-25945, 2001. (Epub 2001 May 7)
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Shalak, V, Kaminska, M, Mitnacht-Kraus, R, Vandenabeele, P, Clauss, M, Mirande, M. The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component J Biol Chem 276, 23769-23776, 2001. (Epub 2001 Apr 16)
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Steidler, L. In situ delivery of cytokines at mucosal surfaces by genetically engineered Lactococcus lactis In Novel Processes and Control Technologies in the Food Industry. (Bozoglu, F, Deak, T, Ray, B, eds.), NATO Science Series, Vol. I 338, Amsterdam, IOS Press, pp. 179-196, 2001. (Epub ---)
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Steidler, L. Lactococcus lactis, a tool for the delivery of therapeutic proteins. Treatment of IBD TheScientificWorld 1, 216-217, 2001. (Epub ---)
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Steidler, L. Microbiological and immunological strategies for treatment of inflammatory bowel disease Microbes Infect 3, 1157-1166, 2001. (Epub ---)
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Tutino, ML, Duilio, A, Parrilli, R, Remaut, E, Sannia, G, Marino, G. A novel replication element from an Antarctic plasmid as a tool for the expression of proteins at low temperature Extremophiles 5, 257-264, 2001. (Epub ---)
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Van Craenenbroeck, K, Vanhoenacker, P, Leysen, JE, Haegeman, G. Evaluation of the tetracycline- and ecdysone-inducible systems for expression of neurotransmitter receptors in mammalian cells Eur J Neurosci 14, 968-976, 2001. (Epub ---)
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Vanderheyde, N, Aksoy, E, Amraoui, Z, Vandenabeele, P, Goldman, M, Willems, F. Tumoricidal activity of monocyte-derived dendritic cells: Evidence for a caspase-8-dependent, Fas-associated death domain-independent mechanism J Immunol 167, 3565-3569, 2001. (Epub ---)
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Vandermeeren, M, Janssens, S, Wouters, H, Borghmans, I, Borgers, M, Beyaert, R, Geysen, J. Dimethylfumarate is an inhibitor of cytokine-induced nuclear translocation of NF-kB1, but not RelA in normal human dermal fibroblast cells J Invest Dermatol 116, 124-130, 2001. (Epub ---)
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Vanhalst, K, Kools, P, Vanden Eynde, E, van Roy, F. The human and murine protocadherin-b one-exon gene families show high evolutionary conservation, despite the difference in gene number FEBS Lett 495, 120-125, 2001. (Epub ---)
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Van Huffel, S, Delaei, F, Heyninck, K, De Valck, D, Beyaert, R. Identification of a novel A20-binding inhibitor of nuclear factor-kB activation termed ABIN-2 J Biol Chem 276, 30216-30223, 2001. (Epub 2001 Jun 4)
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van Loo, G, Schotte, P, van Gurp, M, Demol, H, Hoorelbeke, B, Gevaert, K, Rodriguez, I, Ruiz-Carrillo, A, Vandekerckhove, J, Declercq, W, Beyaert, R, Vandenabeele, P. Endonuclease G: A mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation Cell Death Differ 8, 1136-1142, 2001. (Epub ---)
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Van Petegem, F, Contreras, H, Contreras, R, Van Beeumen, J. Trichoderma reesei alpha-1,2-mannosidase: Structural basis for the cleavage of four consecutive mannose residues J Mol Biol 312, 157-165, 2001. (Epub ---)
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Vantieghem, A, Xu, Y, Declercq, W, Vandenabeele, P, Denecker, G, Vandenheede, JR, Merlevede, W, de Witte, PA, Agostinis, P. Different pathways mediate cytochrome c release after photodynamic therapy with hypericin Photochem Photobiol 74, 133-142, 2001. (Epub ---)
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Vleminckx, K. Adhesive specificity and the evolution of multicellularity In Encyclopedia of Life Sciences. London, Nature Publishing Group, DOI: 10.1038/npg.els.0001273, 2001. (Epub ---)
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Vleminckx, K. Cell adhesion molecules In Encyclopedic Reference of Cancer. (Schwab, M, ed.), Heidelberg, Springer, pp. 181-182, 2001. (Epub ---)
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Vántus, T, Kéri, G, Krivickiene, Z, Valius, M, Steták, A, Keppens, S, Csermely, P, Bauer, PI, Bökönyi, G, Declercq, W, Vandenabeele, P, Merlevede, W, Vandenheede, JR. The somatostatin analogue TT-232 induces apoptosis in A431 cells. Sustained activation of stress-activated kinases and inhibition of signalling to extracellular signal-regulated kinases Cell Signal 13, 717-725, 2001. (Epub ---)
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Waelput, W, Broekaert, D, Vandekerckhove, J, Brouckaert, P, Tavernier, J, Libert, C. A mediator role for metallothionein in tumor necrosis factor-induced lethal shock J Exp Med 194, 1617-1624, 2001. (Epub ---)
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Wieder, T, Essmann, F, Prokop, A, Schmelz, K, Schulze-Osthoff, K, Beyaert, R, Dörken, B, Daniel, PT. Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3 Blood 97, 1378-1387, 2001. (Epub ---)
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Wielockx, B, Bussolino, F, Shapiro, SD, Libert, C. Involvement of a serine protease, but not of neutrophil elastase, in tumor necrosis factor-induced lethal hepatitis and induction of platelet-activating factor J Hepatol 35, 490-497, 2001. (Epub ---)
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Wielockx, B, Hochepied, T, Staelens, J, Van Molle, W, Brouckaert, P, Libert, C. Detection, characterisation and purification of a murine liver factor capable of desensitising towards the lethal activity of tumour necrosis factor Cytokine 15, 59-65, 2001. (Epub ---)
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Wielockx, B, Lannoy, K, Shapiro, SD, Itoh, T, Itohara, S, Vandekerckhove, J, Libert, C. Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy Nat Med 7, 1202-1208, 2001. (Epub ---)
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Assefa, Z, Vantieghem, A, Garmyn, M, Declercq, W, Vandenabeele, P, Vandenheede, JR, Bouillon, R, Merlevede, W, Agostinis, P. p38 Mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis J Biol Chem 275, 21416-21421, 2000. (Epub ---)
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Behrensdorf, HA, Van de Craen, M, Knies, UE, Vandenabeele, P, Clauss, M. The endothelial monocyte-activating polypeptide II (EMAP II) is a substrate for caspase-7 FEBS Lett 466, 143-147, 2000. (Epub ---)
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Beyaert, R, Heyninck, K, Van Huffel, S. A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kB-dependent gene expression and apoptosis Biochem Pharmacol 60, 1143-1151, 2000. (Epub ---)
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Bonné, S, van Hengel, J, van Roy, F. Assignment of the plakophilin-2 gene (PKP2) and a plakophilin-2 pseudogene (PKP2P1) to human chromosome bands 12p11 and 12p13, respectively, by in situ hybridization Cytogenet Cell Genet 88, 286-287, 2000. (Epub ---)
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Boone, E, Vanden Berghe, T, van Loo, G, De Wilde, G, De Wael, N, Vercammen, D, Fiers, W, Haegeman, G, Vandenabeele, P. Structure/function analysis of p55 tumor necrosis factor receptor and Fas-associated death domain. Effect on necrosis in L929sA cells J Biol Chem 275, 37596-37603, 2000. (Epub ---)
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Cauwels, A, Van Molle, W, Janssen, B, Everaerdt, B, Huang, P, Fiers, W, Brouckaert, P. Protection against TNF-induced lethal shock by soluble guanylate cyclase inhibition requires functional inducible nitric oxide synthase Immunity 13, 223-231, 2000. (Epub ---)
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Cornelis, S, Bruynooghe, Y, Denecker, G, Van Huffel, S, Tinton, S, Beyaert, R. Identification and characterization of a novel cell cycle-regulated internal ribosome entry site Mol Cell 5, 597-605, 2000. (Epub ---)
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Daemen, MARC, Heemskerk, VH, van 't Veer, C, Denecker, G, Wolfs, TGAM, Vandenabeele, P, Buurman, WA. Functional protection by acute phase proteins a1-acid glycoprotein and a1-antitrypsin against ischemia/reperfusion injury by preventing apoptosis and inflammation Circulation 102, 1420-1426, 2000. (Epub ---)
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Daemen, MARC, Vandenabeele, P, Buurman, WA. How cells die counts Am J Kidney Dis 36, 665-668, 2000. (Epub ---)
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De Backer, MD, de Hoogt, RA, Froyen, G, Odds, FC, Simons, F, Contreras, R, Luyten, WHML. Single allele knock-out of Candida albicans CGT1 leads to unexpected resistance to hygromycin B and elevated temperature Microbiology 146, 353-365, 2000. (Epub ---)
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De Bosscher, K, Vanden Berghe, W, Haegeman, G. Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: Negative interference of activated glucocorticoid receptor with transcription factors J Neuroimmunol 109, 16-22, 2000. (Epub ---)
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De Bosscher, K, Vanden Berghe, W, Vermeulen, L, Plaisance, S, Boone, E, Haegeman, G. Glucocorticoids repress NF-kB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell Proc Natl Acad Sci USA 97, 3919-3924, 2000. (Epub ---)
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Declercq, W, Logghe, M, Fiers, W, Contreras, R. Cloning and expression of cytokine genes In Cytokine Molecular Biology A Practical Approach. (Balkwill, F, ed.), Oxford, University Press, pp. 1-20, 2000. (Epub ---)
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de Hoogt, R, Luyten, WHML, Contreras, R, De Backer, MD. PCR- and ligation-mediated synthesis of split-marker cassettes with long flanking homology regions for gene disruption in Candida albicans BioTechniques 28, 1112-1116, 2000. (Epub ---)
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Denecker, G, Dooms, H, van Loo, G, Vercammen, D, Grooten, J, Fiers, W, Declercq, W, Vandenabeele, P. Phosphatidyl serine exposure during apoptosis precedes release of cytochrome c and decrease in mitochondrial transmembrane potential FEBS Lett 465, 47-52, 2000. (Epub ---)
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De Vos, K, Severin, F, Van Herreweghe, F, Vancompernolle, K, Goossens, V, Hyman, A, Grooten, J. Tumor necrosis factor induces hyperphosphorylation of kinesin light chain and inhibits kinesin-mediated transport of mitochondria J Cell Biol 149, 1207-1214, 2000. (Epub ---)
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D'Herde, K, De Prest, B, Mussche, S, Schotte, P, Beyaert, R, Van Coster, R, Roels, F. Ultrastructural localization of cytochrome c in apoptosis demonstrates mitochondrial heterogeneity Cell Death Differ 7, 331-337, 2000. (Epub ---)
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Dooms, H, Van Belle, T, Desmedt, M, Rottiers, P, Grooten, J. Interleukin-15 redirects the outcome of a tolerizing T-cell stimulus from apoptosis to anergy Blood 96, 1006-1012, 2000. (Epub ---)
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Eckhart, L, Declercq, W, Ban, J, Rendl, M, Lengauer, B, Mayer, C, Lippens, S, Vandenabeele, P, Tschachler, E. Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation J Invest Dermatol 115, 1148-1151, 2000. (Epub ---)
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Goossens, V, De Vos, K, Vercammen, D, Steemans, M, Vancompernolle, K, Fiers, W, Vandenabeele, P, Grooten, J. Role of reactive oxygen species in tumor necrosis factor toxicity In Antioxidant and Redox Regulation of Genes. (Sen, CK, Sies, H, Baeuerle, PA, eds.), San Diego, Academic Press, pp. 245-264 , 2000. (Epub ---)
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Hecht, A, Vleminckx, K, Stemmler, MP, van Roy, F, Kemler, R. The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates EMBO J 19, 1839-1850, 2000. (Epub ---)
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