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Goossens, V, De Vos, K, Vercammen, D, Steemans, M, Vancompernolle, K, Fiers, W, Vandenabeele, P, Grooten, J.
Redox regulation of TNF signaling
BioFactors 10, 145-156, 1999. (Epub ---)

Goossens, V, Stangé, G, Moens, K, Pipeleers, D, Grooten, J.
Regulation of tumor necrosis factor-induced, mitochondria- and reactive oxygen species-dependent cell death by the electron flux through the electron transport chain complex I
Antiox Redox Signal 1, 285-295, 1999. (Epub ---)

Heyninck, K, Beyaert, R.
The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kB activation at the level of TRAF6
FEBS Lett 442, 147-150, 1999. (Epub ---)

Heyninck, K, Denecker, G, De Valck, D, Fiers, W, Beyaert, R.
Inhibition of tumor necrosis factor-induced necrotic cell death by the zinc finger protein A20
Anticancer Res 19, 2863-2868, 1999. (Epub ---)

Heyninck, K, De Valck, D, Vanden Berghe, W, Van Criekinge, W, Contreras, R, Fiers, W, Haegeman, G, Beyaert, R.
The zinc finger protein A20 inhibits TNF-induced NF-kB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kB-inhibiting protein ABIN
J Cell Biol 145, 1471-1482, 1999. (Epub ---)

Janssens, B, Staes, K, van Roy, F.
Human alpha-catulin, a novel alpha-catenin-like molecule with conserved genomic structure, but deviating alternative splicing
Biochim Biophys Acta 1447, 341-347, 1999. (Epub ---)

Kools, P, Vanhalst, K, Van den Eynde, E, van Roy, F.
The human cadherin-10 gene: Complete coding sequence, predominant expression in the brain, and mapping on chromosome 5p13-14
FEBS Lett 452, 328-334, 1999. (Epub ---)

Kools, P, Vanhalst, K, van Roy, F.
Assignment of cadherin-4 (R-cadherin, CDH4) to human chromosome band 20q13.3
Cytogenet Cell Genet 86, 26-27, 1999. (Epub ---)

Laroy, W, Maras, M, Contreras, R.
Structure-function analysis of human liver a2,6-sialyltransferase
In Sialobiology and Other Novel Forms of Glycosylation. (Inoue, Y, Lee, YC, Troy II, FA, eds.), Osaka, Gakushin, pp. 183-186, 1999. (Epub ---)

Levi, B, Sica, A, Müller-Newen, G, Takahashi, N, Vandenabeele, P, Fish, E.
Jerusalem of cytokines
Cytokine Growth Factor Rev 10, 159-171, 1999. (Epub ---)

Libert, C, Wielockx, B, Grijalba, B, Van Molle, W, Kremmer, E, Colten, HR, Fiers, W, Brouckaert, P.
The role of complement activation in tumour necrosis factor-induced lethal hepatitis
Cytokine 11, 617-625, 1999. (Epub ---)

Libert, C, Wielockx, B, Hammond, GL, Brouckaert, P, Fiers, W, Elliott, RW.
Identification of a locus on distal mouse chromosome 12 that controls resistance to tumor necrosis factor-induced lethal shock
Genomics 55, 284-289, 1999. (Epub ---)

Li, CD, Berx, G, Larsson, C, Auer, G, Aspenblad, U, Pan, Y, Sundelin, B, Ekman, M, Nordenskjöld, M, van Roy, F, Bergerheim, USR.
Distinct deleted regions on chromosome segment 16q23-24 associated with metastases in prostate cancer
Gene Chromos Cancer 24, 175-182, 1999. (Epub ---)

Louagie, H, Schotte, P, Vral, A, Cornelissen, M, Thierens, H, Beyaert, R, De Ridder, L, Philippé, J.
Apoptosis induced by g irradiation in peripheral blood mononuclear cells is not mediated by cytochrome-c release and only partially involves caspase-3-like proteases
Cell Biol Int 23, 611-617, 1999. (Epub ---)

Machado, JC, Soares, P, Carneiro, F, Rocha, A, Beck, S, Blin, N, Berx, G, Sobrinho-Simões, M.
E-cadherin gene mutations provide a genetic basis for the phenotypic divergence of mixed gastric carcinomas
Lab Invest 79, 459-465, 1999. (Epub ---)

Maras, M, De Bruyn, A, Vervecken, W, Uusitalo, J, Penttilä, M, Busson, R, Herdewijn, P, Contreras, R.
In vivo synthesis of complex N-glycans by expression of human N-acetylglucosaminyltransferase I in the filamentous fungus Trichoderma reesei
FEBS Lett 452, 365-370, 1999. (Epub ---)

Maras, M, van Die, I, Contreras, R, van den Hondel, CAMJJ.
Filamentous fungi as production organisms for glycoproteins of bio-medical interest
Glycoconjugate J 16, 99-107, 1999. (Epub ---)

Martinet, W, Van den Plas, D, Raes, H, Reekmans, R, Contreras, R.
Bax-induced cell death in Pichia pastoris
Biotechnol Lett 21, 821-829, 1999. (Epub ---)

Mertens, N, Fiers, W, Remaut, E.
An advanced vector system for high-level recombinant gene expression in Escherichia coli
In Biotechnology International II. (Connor, TH, Weier, H-U, Fox, CF, eds.), San Francisco, Universal Medical Press, pp. 165-171, 1999. (Epub ---)

Neirynck, S, Deroo, T, Saelens, X, Vanlandschoot, P, Min Jou, W, Fiers, W.
A universal influenza A vaccine based on the extracellular domain of the M2 protein
Nat Med 5, 1157-1163, 1999. (Epub ---)

Nollet, F, Berx, G, van Roy, F.
The role of the E-cadherin/catenin adhesion complex in the development and progression of cancer
Mol Cell Biol Res Commun 2, 77-85, 1999. (Epub ---)

Noë, V, Willems, J, Vandekerckhove, J, Van Roy, F, Bruyneel, E, Mareel, M.
Inhibition of adhesion and induction of epithelial cell invasion by HAV-containing E-cadherin-specific peptides
J Cell Sci 112, 127-135, 1999. (Epub ---)

Pattyn, E, Van Ostade, X, Schauvliege, L, Verhee, A, Kalai, M, Vandekerckhove, J, Tavernier, J.
Dimerization of the interferon type I receptor IFNaR2-2 is sufficient for induction of interferon effector genes but not for full antiviral activity
J Biol Chem 274, 34838-34845, 1999. (Epub ---)

Peppelenbosch, M, Boone, E, Jones, GE, van Deventer, SJH, Haegeman, G, Fiers, W, Grooten, J, Ridley, AJ.
Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: Inhibition of Cdc42-mediated filopodium formation by TNF
J Immunol 162, 837-845, 1999. (Epub ---)

Peppelenbosch, MP, Desmedt, M, ten Hove, T, van Deventer, SJH, Grooten, J.
Lipopolysaccharide regulates macrophage fluid phase pinocytosis via CD14-dependent and CD14-independent pathways
Blood 93, 4011-4018, 1999. (Epub ---)

Pynaert, G, Grooten, J, van Deventer, SJH, Peppelenbosch, MP.
Cysteinyl leukotrienes mediate histamine hypersensitivity ex vivo by increasing histamine receptor numbers
Mol Med 5, 685-692, 1999. (Epub ---)

Remaut, E, Bliki, C, Iturizza, M, Keymeulen, K.
Development of regulatable expression systems for cloned genes in cold-adapted prokaryotes
In Biotechnological Applications of Cold-Adapted Organisms. (Margesin, R, Schinner, F, eds.), Berlin-Heidelberg-New York, Springer, pp. 1-16 , 1999. (Epub ---)

Rickers, A, Peters, N, Badock, V, Beyaert, R, Vandenabeele, P, Dörken, B, Bommert, K.
Cleavage of transcription factor SP1 by caspases during anti-IgM-induced B-cell apoptosis
Eur J Biochem 261, 269-274, 1999. (Epub ---)

Rottiers, P, Desmedt, M, Dooms, H, Contreras, R, Grooten, J.
Tumoral environment triggers transcript anomalies in established tumors: Induction of altered gene expression and of aberrant, truncated and B2 repeat-containing gene transcripts
Neoplasia 1, 557-567, 1999. (Epub ---)

Saelens, X, Vanlandschoot, P, Martinet, W, Maras, M, Neirynck, S, Contreras, R, Fiers, W, Min Jou, W.
Protection of mice against a lethal influenza virus challenge after immunization with yeast-derived secreted influenza virus hemagglutinin
Eur J Biochem 260, 166-175, 1999. (Epub ---)

Samowitz, WS, Powers, MD, Spirio, LN, Nollet, F, van Roy, F, Slattery, ML.
beta-Catenin mutations are more frequent in small colorectal adenomas than in larger adenomas and invasive carcinomas
Cancer Res 59, 1442-1444, 1999. (Epub ---)

Schotte, P, Beyaert, R.
A sensitizing function for lithium ions in tumor necrosis factor apoptosis
In Lithium - 50 Years: Recent Advances in Biology and Medicine. (Lucas, KC, Becker, RW, Gallicchio, VS, eds.), Cheshire, Weidner Publishing Group, pp. 153-159, 1999. (Epub ---)

Schotte, P, Declercq, W, Van Huffel, S, Vandenabeele, P, Beyaert, R.
Non-specific effects of methyl ketone peptide inhibitors of caspases
FEBS Lett 442, 117-121, 1999. (Epub ---)

Takahashi, N, Waelput, W, Guisez, Y.
Leptin is an endogenous protective protein against the toxicity exerted by tumor necrosis factor
J Exp Med 189, 207-212, 1999. (Epub ---)

Tejpar, S, Nollet, F, Li, C, Wunder, JS, Michils, G, dal Cin, P, Van Cutsem, E, Bapat, B, van Roy, F, Cassiman, JJ, Alman, BA.
Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor)
Oncogene 18, 6615-6620, 1999. (Epub ---)

Van Criekinge, W, Beyaert, R.
Yeast two-hybrid: State of the art
Biol Proced Online (wwwscienceuwaterlooca/bpo) 2, 1-38, 1999. (Epub ---)

Van Criekinge, W, Cornelis, S, Van de Craen, M, Vandenabeele, P, Fiers, W, Beyaert, R.
GAL4 is a substrate for caspases: Implications for two-hybrid screening and other GAL4-based assays
Mol Cell Biol Res Commun 1, 158-161, 1999. (Epub ---)

Van de Craen, M, Berx, G, Van den brande, I, Fiers, W, Declercq, W, Vandenabeele, P.
Proteolytic cleavage of beta-catenin by caspases: An in vitro analysis
FEBS Lett 458, 167-170, 1999. (Epub ---)

Van de Craen, M, Declercq, W, Van den brande, I, Fiers, W, Vandenabeele, P.
The proteolytic procaspase activation network: An in vitro analysis
Cell Death Differ 6, 1117-1124, 1999. (Epub ---)

Van de Craen, M, De Jonghe, C, Van den brande, I, Declercq, W, Van Gassen, G, Van Criekinge, W, Vanderhoeven, I, Fiers, W, Van Broeckhoven, C, Hendriks, L, Vandenabeele, P.
Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases
FEBS Lett 445, 149-154, 1999. (Epub ---)

Vanden Berghe, W, De Bosscher, K, Boone, E, Plaisance, S, Haegeman, G.
The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter
J Biol Chem 274, 32091-32098, 1999. (Epub ---)

Vanden Berghe, W, Francesconi, E, De Bosscher, K, Resche-Rigon, M, Haegeman, G.
Dissociated glucocorticoids with anti-inflammatory potential repress interleukin-6 gene expression by a nuclear factor-kB-dependent mechanism
Mol Pharmacol 56, 797-806, 1999. (Epub ---)

Van Gassen, G, De Jonghe, C, Pype, S, Van Criekinge, W, Julliams, A, Vanderhoeven, I, Woodrow, S, Beyaert, R, Huylebroeck, D, Van Broeckhoven, C.
Alzheimer's disease associated presenilin 1 interacts with HC5 and ZETA, subunits of the catalytic 20S proteasome
Neurobiol Dis 6, 376-391, 1999. (Epub ---)

van Hengel, J, Vanhoenacker, P, Staes, K, van Roy, F.
Nuclear localization of the p120ctn Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression
Proc Natl Acad Sci USA 96, 7980-7985, 1999. (Epub ---)

Vanhoenacker, P, Gommeren, W, Luyten, WHML, Leysen, JE, Haegeman, G.
Optimized expression of serotonin receptors in mammalian cells using inducible expression systems
Gene Ther Mol Biol 3, 301-310, 1999. (Epub ---)

Van Molle, W, Brouckaert, P, Libert, C.
Caspase-1 is not involved in experimental hepatitis in mouse
FEBS Lett 445, 115-118, 1999. (Epub ---)

Van Molle, W, Denecker, G, Rodriguez, I, Brouckaert, P, Vandenabeele, P, Libert, C.
Activation of caspases in lethal experimental hepatitis and prevention by acute phase proteins
J Immunol 163, 5235-5241, 1999. (Epub ---)

Verhasselt, V, Vanden Berghe, W, Vanderheyde, N, Willems, F, Haegeman, G, Goldman, M.
N-acetyl-L-cysteine inhibits primary human T cell responses at the dendritic cell level: Association with NF-kB inhibition
J Immunol 162, 2569-2574, 1999. (Epub ---)

Vermeulen, SJ, Debruyne, PR, Marra, G, Speleman, FP, Boukamp, P, Jiricny, J, Cuthbert, AP, Newbold, RF, Nollet, FH, van Roy, FM, Mareel, MM.
hMSH6 deficiency and inactivation of the alpha E-catenin invasion-suppressor gene in HCT-8 colon cancer cells
Clin Exp Metastas 17, 663-668, 1999. (Epub ---)

Vermeulen, SJ, Nollet, F, Teugels, E, Vennekens, KM, Malfait, F, Philippé, J, Speleman, F, Bracke, ME, van Roy, FM, Mareel, MM.
The alphaE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells
Oncogene 18, 905-915, 1999. (Epub ---)

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