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Van Molle, W, Wielockx, B, Mahieu, T, Takada, M, Taniguchi, T, Sekikawa, K, Libert, C.
HSP70 protects against TNF-induced lethal inflammatory shock
Immunity 16, 685-695, 2002. (Epub ---)

Vanpoucke, G, Nollet, F, Tejpar, S, Cassiman, J-J, van Roy, F.
The human alpha E-catenin gene CTNNA1: Mutational analysis and rare occurrence of a truncated splice variant
Biochim Biophys Acta 1574, 262-268, 2002. (Epub ---)

Van Roy, F.
In search of sticky protocols (Book Review)
Nat Cell Biol 4, E80, 2002. (Epub ---)

Van Roy, N, Vandesompele, J, Berx, G, Staes, K, Van Gele, M, De Smet, E, De Paepe, A, Laureys, G, van der Drift, P, Versteeg, R, Van Roy, F, Speleman, F.
Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type 1 patients
Genes Chromosomes Cancer 35, 113-120, 2002. (Epub ---)

Varghese, J, Sade, H, Vandenabeele, P, Sarin, A.
Head involution defective (Hid)-triggered apoptosis requires caspase-8 but not FADD (Fas-associated death domain) and is regulated by Erk in mammalian cells
J Biol Chem 277, 3509735104, 2002. (Epub 2002 Jul 16)

Vermeulen, L, De Wilde, G, Notebaert, S, Vanden Berghe, W, Haegeman, G.
Regulation of the transcriptional activity of the nuclear factor-kB p65 subunit
Biochem Pharmacol 64, 963-970, 2002. (Epub ---)

Waelput, W, Brouckaert, P, Broekaert, D, Tavernier, J.
A role for leptin in the systemic inflammatory response syndrome (SIRS) and in immune response
Current Drug Targets Inflamm Allergy 1, 277-289, 2002. (Epub ---)

Ameloot, P, Declercq, W, Fiers, W, Vandenabeele, P, Brouckaert, P.
Heterotrimers formed by tumor necrosis factors of different species or muteins
J Biol Chem 276, 27098-27103, 2001. (Epub 2001 May 22)

Ameloot, P, Fiers, W, De Bleser, P, Ware, CF, Vandenabeele, P, Brouckaert, P.
Identification of tumor necrosis factor (TNF) amino acids crucial for binding to the murine p75 TNF receptor and construction of receptor-selective mutants
J Biol Chem 276, 37426-37430, 2001. (Epub 2001 Jul 11)

Berx, G, Van Roy, F.
The E-cadherin/catenin complex: An important gatekeeper in breast cancer tumorigenesis and malignant progression
Breast Cancer Res 3, 289-293, 2001. (Epub 2001 Jun 28)

Callewaert, N, Geysens, S, Molemans, F, Contreras, R.
Ultrasensitive profiling and sequencing of N-linked oligosaccharides using standard DNA-sequencing equipment
Glycobiology 11, 275-281, 2001. (Epub ---)

Callewaert, N, Laroy, W, Cadirgi, H, Geysens, S, Saelens, X, Min Jou, W, Contreras, R.
Use of HDEL-tagged Trichoderma reesei mannosyl oligosaccharide 1,2-a-D-mannosidase for N-glycan engineering in Pichia pastoris
FEBS Lett 503, 173-178, 2001. (Epub ---)

Clavel, CE, Nollet, F, Berx, G, Tejpar, S, Nawrocki-Raby, B, Kaplan, HH, Van Roy, FM, Birembaut, PL.
Expression of the E-cadherin-catenin complex in lung neuroendocrine tumours
J Pathol 194, 20-26, 2001. (Epub ---)

Comijn, J, Berx, G, Vermassen, P, Verschueren, K, van Grunsven, L, Bruyneel, E, Mareel, M, Huylebroeck, D, van Roy, F.
The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion
Mol Cell 7, 1267-1278, 2001. (Epub ---)

Daemen, MARC, Denecker, G, van 't Veer, C, Wolfs, TGAM, Vandenabeele, P, Buurman, WA.
Activated caspase-1 is not a central mediator of inflammation in the course of ischemia-reperfusion
Transplantation 71, 778-784, 2001. (Epub ---)

De Backer, MD, Nelissen, B, Logghe, M, Viaene, J, Loonen, I, Vandoninck, S, de Hoogt, R, Dewaele, S, Simons, FA, Verhasselt, P, Vanhoof, G, Contreras, R, Luyten, WHML.
An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans
Nat Biotechnol 19, 235-241, 2001. (Epub ---)

De Bosscher, K, Vanden Berghe, W, Haegeman, G.
Glucocorticoid repression of AP-1 is not mediated by competition for nuclear coactivators
Mol Endocrinol 15, 219-227, 2001. (Epub ---)

Denecker, G, Declercq, W, Geuijen, CAW, Boland, A, Benabdillah, R, van Gurp, M, Sory, M-P, Vandenabeele, P, Cornelis, GR.
Yersinia enterocolitica YopP-induced apoptosis of macrophages involves the apoptotic signaling cascade upstream of Bid
J Biol Chem 276, 19706-19714, 2001. (Epub 2001 Mar 14)

Denecker, G, Vercammen, D, Declercq, W, Vandenabeele, P.
Apoptotic and necrotic cell death induced by death domain receptors
Cell Mol Life Sci 58, 356-370, 2001. (Epub ---)

Denecker, G, Vercammen, D, Steemans, M, Vanden Berghe, T, Brouckaert, G, van Loo, G, Zhivotovsky, B, Fiers, W, Grooten, J, Declercq, W, Vandenabeele, P.
Death receptor-induced apoptotic and necrotic cell death: Differential role of caspases and mitochondria
Cell Death Differ 8, 829-840, 2001. (Epub ---)

De Wilde, G, Mertens, N, Boone, E, De Vreese, B, Van Beeumen, J, Fiers, W, Haegeman, G.
Expression in Escherichia coli of the death domain of the human p55 tumor necrosis factor receptor
Protein Expr Purif 23, 226232, 2001. (Epub ---)

De Wilde, G, Murray-Rust, J, Boone, E, Olerenshaw, D, McDonald, NQ, Ibanez, C, Haegeman, G, Wollmer, A, Federwisch, M.
Structure-activity relationship of the p55 TNF receptor death domain and its lymphoproliferation mutants
Eur J Biochem 268, 1382-1391, 2001. (Epub ---)

Dick, JMC, Van Molle, W, Libert, C, Lefebvre, RA.
Antisense knockdown of inducible nitric oxide synthase inhibits the relaxant effect of VIP in isolated smooth muscle cells of the mouse gastric fundus
Br J Pharmacol 134, 425-433, 2001. (Epub ---)

Evans, PC, Taylor, ER, Coadwell, J, Heyninck, K, Beyaert, R, Kilshaw, PJ.
Isolation and characterization of two novel A20-like proteins
Biochem J 357, 617-623, 2001. (Epub ---)

Fiers, W, Neirynck, S, Deroo, T, Saelens, X, Min Jou, W.
Soluble recombinant influenza vaccine
Philos Trans R Soc Lond B Biol Sci 356, 1961-1963, 2001. (Epub ---)

Frame, M, Wan, KF, Tate, R, Vandenabeele, P, Pyne, NJ.
The g subunit of the rod photoreceptor cGMP phosphodiesterase can modulate the proteolysis of two cGMP binding cGMP-specific phosphodiesterases (PDE6 and PDE5) by caspase-3
Cell Signal 13, 735-741, 2001. (Epub ---)

Heyninck, K, Beyaert, R.
Crosstalk between NF-kB-activating and apoptosis-inducing proteins of the TNF-receptor complex
Mol Cell Biol Res Commun 4, 259-265, 2001. (Epub ---)

Janssens, B, Goossens, S, Staes, K, Gilbert, B, van Hengel, J, Colpaert, C, Bruyneel, E, Mareel, M, van Roy, F.
alphaT-Catenin: A novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion
J Cell Sci 114, 3177-3188, 2001. (Epub ---)

Jupp, OJ, McFarlane, SM, Anderson, HM, Littlejohn, AF, Mohamed, AAA, MacKay, RH, Vandenabeele, P, MacEwan, DJ.
Type II tumour necrosis factor-alpha receptor (TNFR2) activates c-Jun N-terminal kinase (JNK) but not mitogen-activated protein kinase (MAPK) or p38 MAPK pathways
Biochem J 359, 525-535, 2001. (Epub ---)

Klinkenberg, M, Van Huffel, S, Heyninck, K, Beyaert, R.
Functional redundancy of the zinc fingers of A20 for inhibition of NF-kB activation and protein-protein interactions
FEBS Lett 498, 93-97, 2001. (Epub ---)

Kotelevets, L, van Hengel, J, Bruyneel, E, Mareel, M, van Roy, F, Chastre, E.
The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness
J Cell Biol 155, 1129-1135, 2001. (Epub 2001 Dec 24)

Laroy, W, Ameloot, P, Contreras, R.
Characterization of sialyltransferase mutants using surface plasmon resonance
Glycobiology 11, 175-182, 2001. (Epub ---)

Machado, JC, Oliveira, C, Carvalho, R, Soares, P, Berx, G, Caldas, C, Seruca, R, Carneiro, F, Sobrinho-Simões, M.
E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma
Oncogene 20, 1525-1528, 2001. (Epub ---)

Marti, A, Ritter, PM, Jäger, R, Lazar, H, Baltzer, A, Schenkel, J, Declercq, W, Vandenabeele, P, Jaggi, R.
Mouse mammary gland involution is associated with cytochrome c release and caspase activation
Mech Dev 104, 89-98, 2001. (Epub ---)

McFarlane, SM, Jupp, OJ, Cobban, HJ, Hunter, I, Anderson, HM, Vandenabeele, P, Nixon, GF, MacEwan, DJ.
Stimulation of stress-activated but not mitogen-activated protein kinases by tumour necrosis factor receptor subtypes in airway smooth muscle
Biochem Pharmacol 61, 749-759, 2001. (Epub ---)

Mertens, N, Schoonjans, R, Willems, A, Schoonooghe, S, Leoen, J, Grooten, J.
New recombinant bi- and trispecific antibody derivatives
In Novel Frontiers in the Production of Compounds for Biomedical Use. (Van Broekhoven, A, Shapiro, F, Anné, J, eds.), Focus on Biotechnology, Vol. 1, Dordrecht, Kluwer Academic Publishers, pp. 195-208, 2001. (Epub ---)

Nawrocki Raby, B, Polette, M, Gilles, C, Clavel, C, Strumane, K, Matos, M, Zahm, J-M, Van Roy, F, Bonnet, N, Birembaut, P.
Quantitative cell dispersion analysis: New test to measure tumor cell aggressiveness
Int J Cancer 93, 644-652, 2001. (Epub ---)

Saelens, X, Kalai, M, Vandenabeele, P.
Translation inhibition in apoptosis. Caspase-dependent PKR activation and eIF2-a phosphorylation
J Biol Chem 276, 41620-41628, 2001. (Epub 2001 Sep 12)

Schoonjans, R, Willems, A, Schoonooghe, S, Leoen, J, Grooten, J, Mertens, N.
A new model for intermediate molecular weight recombinant bispecific and trispecific antibodies by efficient heterodimerization of single chain variable domains through fusion to a Fab-chain
Biomol Eng 17, 193-202, 2001. (Epub ---)

Schotte, P, Schauvliege, R, Janssens, S, Beyaert, R.
The cathepsin B inhibitor z-FA.fmk inhibits cytokine production in macrophages stimulated by lipopolysaccharide
J Biol Chem 276, 21153-21157, 2001. (Epub 2001 Apr 4)

Schotte, P, van Loo, G, Carpentier, I, Vandenabeele, P, Beyaert, R.
Lithium sensitizes tumor cells in an NF-kB-independent way to caspase activation and apoptosis induced by tumor necrosis factor (TNF). Evidence for a role of the TNF receptor-associated death domain protein
J Biol Chem 276, 25939-25945, 2001. (Epub 2001 May 7)

Shalak, V, Kaminska, M, Mitnacht-Kraus, R, Vandenabeele, P, Clauss, M, Mirande, M.
The EMAPII cytokine is released from the mammalian multisynthetase complex after cleavage of its p43/proEMAPII component
J Biol Chem 276, 23769-23776, 2001. (Epub 2001 Apr 16)

Steidler, L.
In situ delivery of cytokines at mucosal surfaces by genetically engineered Lactococcus lactis
In Novel Processes and Control Technologies in the Food Industry. (Bozoglu, F, Deak, T, Ray, B, eds.), NATO Science Series, Vol. I 338, Amsterdam, IOS Press, pp. 179-196, 2001. (Epub ---)

Steidler, L.
Lactococcus lactis, a tool for the delivery of therapeutic proteins. Treatment of IBD
TheScientificWorld 1, 216-217, 2001. (Epub ---)

Steidler, L.
Microbiological and immunological strategies for treatment of inflammatory bowel disease
Microbes Infect 3, 1157-1166, 2001. (Epub ---)

Tutino, ML, Duilio, A, Parrilli, R, Remaut, E, Sannia, G, Marino, G.
A novel replication element from an Antarctic plasmid as a tool for the expression of proteins at low temperature
Extremophiles 5, 257-264, 2001. (Epub ---)

Van Craenenbroeck, K, Vanhoenacker, P, Leysen, JE, Haegeman, G.
Evaluation of the tetracycline- and ecdysone-inducible systems for expression of neurotransmitter receptors in mammalian cells
Eur J Neurosci 14, 968-976, 2001. (Epub ---)

Vanderheyde, N, Aksoy, E, Amraoui, Z, Vandenabeele, P, Goldman, M, Willems, F.
Tumoricidal activity of monocyte-derived dendritic cells: Evidence for a caspase-8-dependent, Fas-associated death domain-independent mechanism
J Immunol 167, 3565-3569, 2001. (Epub ---)

Vandermeeren, M, Janssens, S, Wouters, H, Borghmans, I, Borgers, M, Beyaert, R, Geysen, J.
Dimethylfumarate is an inhibitor of cytokine-induced nuclear translocation of NF-kB1, but not RelA in normal human dermal fibroblast cells
J Invest Dermatol 116, 124-130, 2001. (Epub ---)

Vanhalst, K, Kools, P, Vanden Eynde, E, van Roy, F.
The human and murine protocadherin-b one-exon gene families show high evolutionary conservation, despite the difference in gene number
FEBS Lett 495, 120-125, 2001. (Epub ---)

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