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Vleminckx, K.
Cell adhesion molecules
In Encyclopedic Reference of Cancer. (Schwab, M, ed.), Heidelberg, Springer, pp. 181-182, 2001. (Epub ---)

Vántus, T, Kéri, G, Krivickiene, Z, Valius, M, Steták, A, Keppens, S, Csermely, P, Bauer, PI, Bökönyi, G, Declercq, W, Vandenabeele, P, Merlevede, W, Vandenheede, JR.
The somatostatin analogue TT-232 induces apoptosis in A431 cells. Sustained activation of stress-activated kinases and inhibition of signalling to extracellular signal-regulated kinases
Cell Signal 13, 717-725, 2001. (Epub ---)

Waelput, W, Broekaert, D, Vandekerckhove, J, Brouckaert, P, Tavernier, J, Libert, C.
A mediator role for metallothionein in tumor necrosis factor-induced lethal shock
J Exp Med 194, 1617-1624, 2001. (Epub ---)

Wieder, T, Essmann, F, Prokop, A, Schmelz, K, Schulze-Osthoff, K, Beyaert, R, Dörken, B, Daniel, PT.
Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3
Blood 97, 1378-1387, 2001. (Epub ---)

Wielockx, B, Bussolino, F, Shapiro, SD, Libert, C.
Involvement of a serine protease, but not of neutrophil elastase, in tumor necrosis factor-induced lethal hepatitis and induction of platelet-activating factor
J Hepatol 35, 490-497, 2001. (Epub ---)

Wielockx, B, Hochepied, T, Staelens, J, Van Molle, W, Brouckaert, P, Libert, C.
Detection, characterisation and purification of a murine liver factor capable of desensitising towards the lethal activity of tumour necrosis factor
Cytokine 15, 59-65, 2001. (Epub ---)

Wielockx, B, Lannoy, K, Shapiro, SD, Itoh, T, Itohara, S, Vandekerckhove, J, Libert, C.
Inhibition of matrix metalloproteinases blocks lethal hepatitis and apoptosis induced by tumor necrosis factor and allows safe antitumor therapy
Nat Med 7, 1202-1208, 2001. (Epub ---)

Assefa, Z, Vantieghem, A, Garmyn, M, Declercq, W, Vandenabeele, P, Vandenheede, JR, Bouillon, R, Merlevede, W, Agostinis, P.
p38 Mitogen-activated protein kinase regulates a novel, caspase-independent pathway for the mitochondrial cytochrome c release in ultraviolet B radiation-induced apoptosis
J Biol Chem 275, 21416-21421, 2000. (Epub ---)

Behrensdorf, HA, Van de Craen, M, Knies, UE, Vandenabeele, P, Clauss, M.
The endothelial monocyte-activating polypeptide II (EMAP II) is a substrate for caspase-7
FEBS Lett 466, 143-147, 2000. (Epub ---)

Beyaert, R, Heyninck, K, Van Huffel, S.
A20 and A20-binding proteins as cellular inhibitors of nuclear factor-kB-dependent gene expression and apoptosis
Biochem Pharmacol 60, 1143-1151, 2000. (Epub ---)

Bonné, S, van Hengel, J, van Roy, F.
Assignment of the plakophilin-2 gene (PKP2) and a plakophilin-2 pseudogene (PKP2P1) to human chromosome bands 12p11 and 12p13, respectively, by in situ hybridization
Cytogenet Cell Genet 88, 286-287, 2000. (Epub ---)

Boone, E, Vanden Berghe, T, van Loo, G, De Wilde, G, De Wael, N, Vercammen, D, Fiers, W, Haegeman, G, Vandenabeele, P.
Structure/function analysis of p55 tumor necrosis factor receptor and Fas-associated death domain. Effect on necrosis in L929sA cells
J Biol Chem 275, 37596-37603, 2000. (Epub ---)

Cauwels, A, Van Molle, W, Janssen, B, Everaerdt, B, Huang, P, Fiers, W, Brouckaert, P.
Protection against TNF-induced lethal shock by soluble guanylate cyclase inhibition requires functional inducible nitric oxide synthase
Immunity 13, 223-231, 2000. (Epub ---)

Cornelis, S, Bruynooghe, Y, Denecker, G, Van Huffel, S, Tinton, S, Beyaert, R.
Identification and characterization of a novel cell cycle-regulated internal ribosome entry site
Mol Cell 5, 597-605, 2000. (Epub ---)

Daemen, MARC, Heemskerk, VH, van 't Veer, C, Denecker, G, Wolfs, TGAM, Vandenabeele, P, Buurman, WA.
Functional protection by acute phase proteins a1-acid glycoprotein and a1-antitrypsin against ischemia/reperfusion injury by preventing apoptosis and inflammation
Circulation 102, 1420-1426, 2000. (Epub ---)

Daemen, MARC, Vandenabeele, P, Buurman, WA.
How cells die counts
Am J Kidney Dis 36, 665-668, 2000. (Epub ---)

De Backer, MD, de Hoogt, RA, Froyen, G, Odds, FC, Simons, F, Contreras, R, Luyten, WHML.
Single allele knock-out of Candida albicans CGT1 leads to unexpected resistance to hygromycin B and elevated temperature
Microbiology 146, 353-365, 2000. (Epub ---)

De Bosscher, K, Vanden Berghe, W, Haegeman, G.
Mechanisms of anti-inflammatory action and of immunosuppression by glucocorticoids: Negative interference of activated glucocorticoid receptor with transcription factors
J Neuroimmunol 109, 16-22, 2000. (Epub ---)

De Bosscher, K, Vanden Berghe, W, Vermeulen, L, Plaisance, S, Boone, E, Haegeman, G.
Glucocorticoids repress NF-kB-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell
Proc Natl Acad Sci USA 97, 3919-3924, 2000. (Epub ---)

Declercq, W, Logghe, M, Fiers, W, Contreras, R.
Cloning and expression of cytokine genes
In Cytokine Molecular Biology A Practical Approach. (Balkwill, F, ed.), Oxford, University Press, pp. 1-20, 2000. (Epub ---)

de Hoogt, R, Luyten, WHML, Contreras, R, De Backer, MD.
PCR- and ligation-mediated synthesis of split-marker cassettes with long flanking homology regions for gene disruption in Candida albicans
BioTechniques 28, 1112-1116, 2000. (Epub ---)

Denecker, G, Dooms, H, van Loo, G, Vercammen, D, Grooten, J, Fiers, W, Declercq, W, Vandenabeele, P.
Phosphatidyl serine exposure during apoptosis precedes release of cytochrome c and decrease in mitochondrial transmembrane potential
FEBS Lett 465, 47-52, 2000. (Epub ---)

De Vos, K, Severin, F, Van Herreweghe, F, Vancompernolle, K, Goossens, V, Hyman, A, Grooten, J.
Tumor necrosis factor induces hyperphosphorylation of kinesin light chain and inhibits kinesin-mediated transport of mitochondria
J Cell Biol 149, 1207-1214, 2000. (Epub ---)

D'Herde, K, De Prest, B, Mussche, S, Schotte, P, Beyaert, R, Van Coster, R, Roels, F.
Ultrastructural localization of cytochrome c in apoptosis demonstrates mitochondrial heterogeneity
Cell Death Differ 7, 331-337, 2000. (Epub ---)

Dooms, H, Van Belle, T, Desmedt, M, Rottiers, P, Grooten, J.
Interleukin-15 redirects the outcome of a tolerizing T-cell stimulus from apoptosis to anergy
Blood 96, 1006-1012, 2000. (Epub ---)

Eckhart, L, Declercq, W, Ban, J, Rendl, M, Lengauer, B, Mayer, C, Lippens, S, Vandenabeele, P, Tschachler, E.
Terminal differentiation of human keratinocytes and stratum corneum formation is associated with caspase-14 activation
J Invest Dermatol 115, 1148-1151, 2000. (Epub ---)

Goossens, V, De Vos, K, Vercammen, D, Steemans, M, Vancompernolle, K, Fiers, W, Vandenabeele, P, Grooten, J.
Role of reactive oxygen species in tumor necrosis factor toxicity
In Antioxidant and Redox Regulation of Genes. (Sen, CK, Sies, H, Baeuerle, PA, eds.), San Diego, Academic Press, pp. 245-264 , 2000. (Epub ---)

Hecht, A, Vleminckx, K, Stemmler, MP, van Roy, F, Kemler, R.
The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates
EMBO J 19, 1839-1850, 2000. (Epub ---)

Hochepied, T, Ameloot, P, Brouckaert, P, Van Leuven, F, Libert, C.
Differential response of a2-macroglobulin-deficient mice in models of lethal TNF-induced inflammation
Eur Cytokine Netw 11, 597-601, 2000. (Epub ---)

Hochepied, T, Van Molle, W, Berger, FG, Baumann, H, Libert, C.
Involvement of the acute phase protein a1-acid glycoprotein in nonspecific resistance to a lethal Gram-negative infection
J Biol Chem 275, 14903-14909, 2000. (Epub ---)

Huston, E, Beard, M, McCallum, F, Pyne, NJ, Vandenabeele, P, Scotland, G, Houslay, MD.
The cAMP-specific phosphodiesterase PDE4A5 is cleaved downstream of its SH3 interaction domain by caspase-3. Consequences for altered intracellular distribution
J Biol Chem 275, 28063-28074, 2000. (Epub ---)

Keilhack, H, Hellman, U, van Hengel, J, van Roy, F, Godovac-Zimmermann, J, Böhmer, F-D.
The protein-tyrosine phosphatase SHP-1 binds to and dephosphorylates p120 catenin
J Biol Chem 275, 26376-26384, 2000. (Epub ---)

Kools, P, Van Imschoot, G, van Roy, F.
Characterization of three novel human cadherin genes clustered on chromosome 18q22-23 and with high homology to chicken cadherin-7
Genomics 68, 283-295, 2000. (Epub ---)

Laroy, W, Contreras, R.
Cloning of Trypanosoma cruzi trans-sialidase and expression in Pichia pastoris
Protein Expr Purif 20, 389-393, 2000. (Epub ---)

Lippens, S, Kockx, M, Knaapen, M, Mortier, L, Polakowska, R, Verheyen, A, Garmyn, M, Zwijsen, A, Formstecher, P, Huylebroeck, D, Vandenabeele, P, Declercq, W.
Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing
Cell Death Differ 7, 1218-1224, 2000. (Epub ---)

Maras, M, Callewaert, N, Piens, K, Claeyssens, M, Martinet, W, Dewaele, S, Contreras, H, Dewerte, I, Penttilä, M, Contreras, R.
Molecular cloning and enzymatic characterization of a Trichoderma reesei 1,2-a-D-mannosidase
J Biotechnol 77, 255-263, 2000. (Epub ---)

Nollet, F, Kools, P, van Roy, F.
Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members
J Mol Biol 299, 551-572, 2000. (Epub ---)

O'Neil, D.
Web alert. Gene therapy in cancer treatment
Curr Opin Mol Ther 2, 359, 2000. (Epub ---)

O'Neil, D.
Web alert. Viruses as vectors for gene transfer
Curr Opin Mol Ther 2, 484-485, 2000. (Epub ---)

O'Neil, D, Jones, D.
Web alert. Genomics and proteomics
Curr Opin Mol Ther 2, 621-622, 2000. (Epub ---)

Penning, L, Denecker, G, Vercammen, D, Declercq, W, Schipper, RG, Vandenabeele, P.
A role for potassium in TNF-induced apoptosis and gene-induction in human and rodent tumour cell lines
Cytokine 12, 747-750, 2000. (Epub ---)

Peppelenbosch, MP, Desmedt, M, Pynaert, G, van Deventer, SJH, Grooten, J.
Macrophages present pinocytosed exogenous antigen via MHC class I whereas antigen ingested by receptor-mediated endocytosis is presented via MHC class II
J Immunol 165, 1984-1991, 2000. (Epub ---)

Pype, S, Declercq, W, Ibrahimi, A, Michiels, C, Van Rietschoten, JGL, Dewulf, N, de Boer, M, Vandenabeele, P, Huylebroeck, D, Remacle, JE.
TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kB activation
J Biol Chem 275, 18586-18593, 2000. (Epub ---)

Schoonjans, R, Willems, A, Grooten, J, Mertens, N.
Efficient heterodimerization of recombinant bi- and trispecific antibodies
Bioseparation 9, 179-183, 2000. (Epub ---)

Schoonjans, R, Willems, A, Schoonooghe, S, Fiers, W, Grooten, J, Mertens, N.
Fab chains as an efficient heterodimerization scaffold for the production of recombinant bispecific and trispecific antibody derivatives
J Immunol 165, 7050-7057, 2000. (Epub ---)

Schotte, L, Steidler, L, Vandekerckhove, J, Remaut, E.
Secretion of biologically active murine interleukin-10 by Lactococcus lactis
Enzyme Microb Technol 27, 761-765, 2000. (Epub ---)

Steidler, L, Hans, W, Schotte, L, Neirynck, S, Obermeier, F, Falk, W, Fiers, W, Remaut, E.
Treatment of murine colitis by Lactococcus lactis secreting interleukin-10
Science 289, 1352-1355, 2000. (Epub ---)

Vancompernolle, K, Boonefaes, T, Mann, M, Fiers, W, Grooten, J.
Tumor necrosis factor-induced microtubule stabilization mediated by hyperphosphorylated oncoprotein 18 promotes cell death
J Biol Chem 275, 33876-33882, 2000. (Epub ---)

Van Craenenbroeck, K, Vanhoenacker, P, Duchau, H, Haegeman, G.
Molecular integrity and usefulness of episomal expression vectors derived from BK and Epstein-Barr virus
Gene 253, 293-301, 2000. (Epub ---)

Van Craenenbroeck, K, Vanhoenacker, P, Haegeman, G.
Episomal vectors for gene expression in mammalian cells
Eur J Biochem 267, 5665-5678, 2000. (Epub ---)

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