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Noë, V, Willems, J, Vandekerckhove, J, Van Roy, F, Bruyneel, E, Mareel, M.
Inhibition of adhesion and induction of epithelial cell invasion by HAV-containing E-cadherin-specific peptides
J Cell Sci 112, 127-135, 1999. (Epub ---)

Pattyn, E, Van Ostade, X, Schauvliege, L, Verhee, A, Kalai, M, Vandekerckhove, J, Tavernier, J.
Dimerization of the interferon type I receptor IFNaR2-2 is sufficient for induction of interferon effector genes but not for full antiviral activity
J Biol Chem 274, 34838-34845, 1999. (Epub ---)

Peppelenbosch, M, Boone, E, Jones, GE, van Deventer, SJH, Haegeman, G, Fiers, W, Grooten, J, Ridley, AJ.
Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: Inhibition of Cdc42-mediated filopodium formation by TNF
J Immunol 162, 837-845, 1999. (Epub ---)

Peppelenbosch, MP, Desmedt, M, ten Hove, T, van Deventer, SJH, Grooten, J.
Lipopolysaccharide regulates macrophage fluid phase pinocytosis via CD14-dependent and CD14-independent pathways
Blood 93, 4011-4018, 1999. (Epub ---)

Pynaert, G, Grooten, J, van Deventer, SJH, Peppelenbosch, MP.
Cysteinyl leukotrienes mediate histamine hypersensitivity ex vivo by increasing histamine receptor numbers
Mol Med 5, 685-692, 1999. (Epub ---)

Remaut, E, Bliki, C, Iturizza, M, Keymeulen, K.
Development of regulatable expression systems for cloned genes in cold-adapted prokaryotes
In Biotechnological Applications of Cold-Adapted Organisms. (Margesin, R, Schinner, F, eds.), Berlin-Heidelberg-New York, Springer, pp. 1-16 , 1999. (Epub ---)

Rickers, A, Peters, N, Badock, V, Beyaert, R, Vandenabeele, P, Dörken, B, Bommert, K.
Cleavage of transcription factor SP1 by caspases during anti-IgM-induced B-cell apoptosis
Eur J Biochem 261, 269-274, 1999. (Epub ---)

Rottiers, P, Desmedt, M, Dooms, H, Contreras, R, Grooten, J.
Tumoral environment triggers transcript anomalies in established tumors: Induction of altered gene expression and of aberrant, truncated and B2 repeat-containing gene transcripts
Neoplasia 1, 557-567, 1999. (Epub ---)

Saelens, X, Vanlandschoot, P, Martinet, W, Maras, M, Neirynck, S, Contreras, R, Fiers, W, Min Jou, W.
Protection of mice against a lethal influenza virus challenge after immunization with yeast-derived secreted influenza virus hemagglutinin
Eur J Biochem 260, 166-175, 1999. (Epub ---)

Samowitz, WS, Powers, MD, Spirio, LN, Nollet, F, van Roy, F, Slattery, ML.
beta-Catenin mutations are more frequent in small colorectal adenomas than in larger adenomas and invasive carcinomas
Cancer Res 59, 1442-1444, 1999. (Epub ---)

Schotte, P, Beyaert, R.
A sensitizing function for lithium ions in tumor necrosis factor apoptosis
In Lithium - 50 Years: Recent Advances in Biology and Medicine. (Lucas, KC, Becker, RW, Gallicchio, VS, eds.), Cheshire, Weidner Publishing Group, pp. 153-159, 1999. (Epub ---)

Schotte, P, Declercq, W, Van Huffel, S, Vandenabeele, P, Beyaert, R.
Non-specific effects of methyl ketone peptide inhibitors of caspases
FEBS Lett 442, 117-121, 1999. (Epub ---)

Takahashi, N, Waelput, W, Guisez, Y.
Leptin is an endogenous protective protein against the toxicity exerted by tumor necrosis factor
J Exp Med 189, 207-212, 1999. (Epub ---)

Tejpar, S, Nollet, F, Li, C, Wunder, JS, Michils, G, dal Cin, P, Van Cutsem, E, Bapat, B, van Roy, F, Cassiman, JJ, Alman, BA.
Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor)
Oncogene 18, 6615-6620, 1999. (Epub ---)

Van Criekinge, W, Beyaert, R.
Yeast two-hybrid: State of the art
Biol Proced Online (wwwscienceuwaterlooca/bpo) 2, 1-38, 1999. (Epub ---)

Van Criekinge, W, Cornelis, S, Van de Craen, M, Vandenabeele, P, Fiers, W, Beyaert, R.
GAL4 is a substrate for caspases: Implications for two-hybrid screening and other GAL4-based assays
Mol Cell Biol Res Commun 1, 158-161, 1999. (Epub ---)

Van de Craen, M, Berx, G, Van den brande, I, Fiers, W, Declercq, W, Vandenabeele, P.
Proteolytic cleavage of beta-catenin by caspases: An in vitro analysis
FEBS Lett 458, 167-170, 1999. (Epub ---)

Van de Craen, M, Declercq, W, Van den brande, I, Fiers, W, Vandenabeele, P.
The proteolytic procaspase activation network: An in vitro analysis
Cell Death Differ 6, 1117-1124, 1999. (Epub ---)

Van de Craen, M, De Jonghe, C, Van den brande, I, Declercq, W, Van Gassen, G, Van Criekinge, W, Vanderhoeven, I, Fiers, W, Van Broeckhoven, C, Hendriks, L, Vandenabeele, P.
Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases
FEBS Lett 445, 149-154, 1999. (Epub ---)

Vanden Berghe, W, De Bosscher, K, Boone, E, Plaisance, S, Haegeman, G.
The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter
J Biol Chem 274, 32091-32098, 1999. (Epub ---)

Vanden Berghe, W, Francesconi, E, De Bosscher, K, Resche-Rigon, M, Haegeman, G.
Dissociated glucocorticoids with anti-inflammatory potential repress interleukin-6 gene expression by a nuclear factor-kB-dependent mechanism
Mol Pharmacol 56, 797-806, 1999. (Epub ---)

Van Gassen, G, De Jonghe, C, Pype, S, Van Criekinge, W, Julliams, A, Vanderhoeven, I, Woodrow, S, Beyaert, R, Huylebroeck, D, Van Broeckhoven, C.
Alzheimer's disease associated presenilin 1 interacts with HC5 and ZETA, subunits of the catalytic 20S proteasome
Neurobiol Dis 6, 376-391, 1999. (Epub ---)

van Hengel, J, Vanhoenacker, P, Staes, K, van Roy, F.
Nuclear localization of the p120ctn Armadillo-like catenin is counteracted by a nuclear export signal and by E-cadherin expression
Proc Natl Acad Sci USA 96, 7980-7985, 1999. (Epub ---)

Vanhoenacker, P, Gommeren, W, Luyten, WHML, Leysen, JE, Haegeman, G.
Optimized expression of serotonin receptors in mammalian cells using inducible expression systems
Gene Ther Mol Biol 3, 301-310, 1999. (Epub ---)

Van Molle, W, Brouckaert, P, Libert, C.
Caspase-1 is not involved in experimental hepatitis in mouse
FEBS Lett 445, 115-118, 1999. (Epub ---)

Van Molle, W, Denecker, G, Rodriguez, I, Brouckaert, P, Vandenabeele, P, Libert, C.
Activation of caspases in lethal experimental hepatitis and prevention by acute phase proteins
J Immunol 163, 5235-5241, 1999. (Epub ---)

Verhasselt, V, Vanden Berghe, W, Vanderheyde, N, Willems, F, Haegeman, G, Goldman, M.
N-acetyl-L-cysteine inhibits primary human T cell responses at the dendritic cell level: Association with NF-kB inhibition
J Immunol 162, 2569-2574, 1999. (Epub ---)

Vermeulen, SJ, Debruyne, PR, Marra, G, Speleman, FP, Boukamp, P, Jiricny, J, Cuthbert, AP, Newbold, RF, Nollet, FH, van Roy, FM, Mareel, MM.
hMSH6 deficiency and inactivation of the alpha E-catenin invasion-suppressor gene in HCT-8 colon cancer cells
Clin Exp Metastas 17, 663-668, 1999. (Epub ---)

Vermeulen, SJ, Nollet, F, Teugels, E, Vennekens, KM, Malfait, F, Philippé, J, Speleman, F, Bracke, ME, van Roy, FM, Mareel, MM.
The alphaE-catenin gene (CTNNA1) acts as an invasion-suppressor gene in human colon cancer cells
Oncogene 18, 905-915, 1999. (Epub ---)

Becker, K-F, Reich, U, Schott, C, Becker, I, Berx, G, van Roy, F, Höfler, H.
Mutation in Brief: Identification of eleven novel tumor-associated E-cadherin mutations
Hum Mutat 13, 171 (#215 Online), 1998. (Epub ---)

Berx, G, Becker, K-F, Höfler, H, van Roy, F.
Mutation Update: Mutations of the human E-cadherin (CDH1) gene
Hum Mutat 12, 226-237, 1998. (Epub ---)

Berx, G, Nollet, F, van Roy, F.
Dysregulation of the E-cadherin/catenin complex by irreversible mutations in human carcinomas
Cell Adhes Commun 6, 171-184, 1998. (Epub ---)

Beyaert, R, Fiers, W.
Tumor necrosis factor and lymphotoxin
In Cytokines. (Mire-Sluis, AR, Thorpe, R, eds.), San Diego, Academic Press, pp. 335-360, 1998. (Epub ---)

Bonné, S, van Hengel, J, van Roy, F.
Chromosomal mapping of human armadillo genes belonging to the p120ctn/plakophilin subfamily
Genomics 51, 452-454, 1998. (Epub ---)

Boone, E, Vandevoorde, V, De Wilde, G, Haegeman, G.
Activation of p42/p44 mitogen-activated protein kinases (MAPK) and p38 MAPK by tumor necrosis factor (TNF) is mediated through the death domain of the 55-kDa TNF receptor
FEBS Lett 441, 275-280, 1998. (Epub ---)

Brouckaert, P.
Septic shock
In Encyclopedia of Immunology. (Delves, PJ, Roitt, IM, eds.), 2nd ed., London, Academic Press, pp. 2161-2164, 1998. (Epub ---)

Carpentier, I, Declercq, W, Malinin, NL, Wallach, D, Fiers, W, Beyaert, R.
TRAF2 plays a dual role in NF-kB-dependent gene activation by mediating the TNF-induced activation of p38 MAPK and IkB kinase pathways
FEBS Lett 425, 195-198, 1998. (Epub ---)

De Bruyn, A, Schraml, J, Maras, M, Contreras, R, Herdewijn, P.
NMR techniques in the study of protein-linked carbohydrates
In Carbohydrates from Trichoderma reesei and Other Microorganisms Structures, Biochemistry, Genetics and Applications. (Claeyssens, M, Nerinckx, W, Piens, K, eds.), London, The Royal Society of Chemistry, pp. 315-322, 1998. (Epub ---)

Declercq, W, Denecker, G, Fiers, W, Vandenabeele, P.
Cooperation of both TNF receptors in inducing apoptosis: Involvement of the TNF receptor-associated factor binding domain of the TNF receptor 75
J Immunol 161, 390-399, 1998. (Epub ---)

Decoster, E, Cornelis, S, Vanhaesebroeck, B, Fiers, W.
Autocrine tumor necrosis factor (TNF) and lymphotoxin (LT) a differentially modulate cellular sensitivity to TNF/LT-a cytotoxicity in L929 cells
J Cell Biol 143, 2057-2065, 1998. (Epub ---)

Decoster, E, Vanhaesebroeck, B, Boone, E, Plaisance, S, De Vos, K, Haegeman, G, Grooten, J, Fiers, W.
Induction of unresponsiveness to tumor necrosis factor (TNF) after autocrine TNF expression requires TNF membrane retention
J Biol Chem 273, 3271-3277, 1998. (Epub ---)

Desmedt, M, Rottiers, P, Dooms, H, Fiers, W, Grooten, J.
Macrophages induce cellular immunity by activating Th1 cell responses and suppressing Th2 cell responses
J Immunol 160, 5300-5308, 1998. (Epub ---)

De Valck, D, Vercammen, D, Fiers, W, Beyaert, R.
Differential activation of phospholipases during necrosis or apoptosis: A comparative study using tumor necrosis factor and anti-Fas antibodies
J Cell Biochem 71, 392-399, 1998. (Epub ---)

De Vos, K, Goossens, V, Boone, E, Vercammen, D, Vancompernolle, K, Vandenabeele, P, Haegeman, G, Fiers, W, Grooten, J.
The 55-kDa tumor necrosis factor receptor induces clustering of mitochondria through its membrane-proximal region
J Biol Chem 273, 9673-9680, 1998. (Epub ---)

Dooms, H, Desmedt, M, Vancaeneghem, S, Rottiers, P, Goossens, V, Fiers, W, Grooten, J.
Quiescence-inducing and antiapoptotic activities of IL-15 enhance secondary CD4+ T cell responsiveness to antigen
J Immunol 161, 2141-2150, 1998. (Epub ---)

Dumont, A, Hehner, SP, Schmitz, ML, Gustafsson, J-Å, Lidén, J, Okret, S, van der Saag, PT, Wissink, S, van der Burg, B, Herrlich, P, Haegeman, G, De Bosscher, K, Fiers, W.
Cross-talk between steroids and NF-kB: What language?
Trends Biochem Sci 23, 233-235, 1998. (Epub ---)

Guisez, Y, Faché, I, Campfield, LA, Smith, FJ, Farid, A, Plaetinck, G, Van der Heyden, J, Tavernier, J, Fiers, W, Burn, P, Devos, R.
Efficient secretion of biologically active recombinant OB protein (leptin) in Escherichia coli, purification from the periplasm and characterization
Protein Expr Purif 12, 249-258, 1998. (Epub ---)

Keirsebilck, A, Bonné, S, Bruyneel, E, Vermassen, P, Lukanidin, E, Mareel, M, van Roy, F.
E-cadherin and metastasin (mts-1/S100A4) expression levels are inversely regulated in two tumor cell families
Cancer Res 58, 4587-4591, 1998. (Epub ---)

Keirsebilck, A, Bonné, S, Staes, K, van Hengel, J, Nollet, F, Reynolds, A, van Roy, F.
Molecular cloning of the human p120ctn catenin gene (CTNND1): Expression of multiple alternatively spliced isoforms
Genomics 50, 129-146, 1998. (Epub ---)

Keirsebilck, A, Van Hoorde, L, Gao, Y, De Bruyne, G, Bruyneel, E, Vermassen, P, Mareel, M, van Roy, F.
Mechanisms of downregulation of transfected E-cadherin cDNA during formation of invasive tumors in syngeneic mice
Invasion Metastasis 18, 44-56, 1998. (Epub ---)

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