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Huppertsberg, A, Kaps, L, Zhong, Z, Schmitt, S, Stickdorn, J, Deswarte, K, Combes, F, Czysch, C, De Vrieze, J, Kasmi, S, Choteschovsky, N, Klefenz, A, Medina-Montano, C, Winterwerber, P, Chen, C, Bros, M, Lienenklaus, S, Sanders, NN, Koynov, K, et al..
Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-like Receptor 7/8 Agonistic Immune Modulators
J Am Chem Soc 143, 9872-9883, 2021. (Epub 2021 Jun 24)

Iliaki, S, Beyaert, R, Afonina, IS.
Polo-like kinase 1 (PLK1) signaling in cancer and beyond
Biochem Pharmacol 193, 114747, 2021. (Epub 2021 Aug 26)

Jangra, S, De Vrieze, J, Choi, A, Rathnasinghe, R, Laghlali, G, Uvyn, A, Van Herck, S, Nuhn, L, Deswarte, K, Zhong, Z, Sanders, N, Lienenklaus, S, David, S, Strohmeier, S, Amanat, F, Krammer, F, Hammad, H, Lambrecht, BN, Coughlan, L, et al..
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine
Angew Chem Int Ed Engl 60, 9467-9473, 2021. (Epub 2021 Jan 19)

Jans, LBO, Chen, M, Elewaut, D, Van den Bosch, F, Carron, P, Jacques, P, Wittoek, R, Jaremko, JL, Herregods, N.
MRI-based Synthetic CT in the Detection of Structural Lesions in Patients with Suspected Sacroiliitis: Comparison with MRI
Radiology 298, 343-349, 2021. (Epub 2020 Dec 22)

Joeris, T, Gomez-Casado, C, Holmkvist, P, Tavernier, SJ, Silva-Sanchez, A, Klotz, L, Randall, TD, Mowat, AM, Kotarsky, K, Malissen, B, Agace, WW.
Intestinal cDC1 drive cross-tolerance to epithelial-derived antigen via induction of FoxP3(+)CD8(+) Tregs
Sci Immunol 6, eabd3774, 2021. (Epub 2021 Jun 4)

Kananen, L, Enroth, L, Raitanen, J, Jylhava, J, Burkle, A, Moreno-Villanueva, M, Bernhardt, J, Toussaint, O, Grubeck-Loebenstein, B, Malavolta, M, Basso, A, Piacenza, F, Collino, S, Gonos, ES, Sikora, E, Gradinaru, D, Jansen, E, Dolle, MET, Salmon, M, et al..
Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains
Sci Rep 11, 6139, 2021. (Epub 2021 Mar 17)

Karow, F, Smiljanovic, B, Grun, JR, Poddubnyy, D, Proft, F, Talpin, A, Hue, C, Boland, A, Deleuze, JF, Garchon, HJ, Ergenc, I, De Craemer, AS, Erben, U, Haupl, T, Elewaut, D, Breban, M, Grutzkau, A, Syrbe, U.
Monocyte transcriptomes from patients with axial spondyloarthritis reveal dysregulated monocytopoiesis and a distinct inflammatory imprint
Arthritis Res Ther 23, 246, 2021. (Epub 2021 Sep 24)

Kelley, SM, Ravichandran, KS.
Putting the brakes on phagocytosis: "don't-eat-me" signaling in physiology and disease
EMBO Rep 22, e52564, 2021. (Epub 2021 May 27)

Kiltz, U, Wei, JC, van der Heijde, D, van den Bosch, F, Walsh, JA, Boonen, A, Gensler, LS, Hunter, T, Carlier, H, Dong, Y, Li, X, Bolce, R, Strand, V, Braun, J.
Ixekizumab Improves Functioning and Health in the Treatment of Radiographic Axial Spondyloarthritis: Week 52 Results from 2 pivotal studies
J Rheumatol 48, 188-197, 2021. (Epub 2020 Jul 15)

Kim, JS, Kolesnikov, M, Peled-Hajaj, S, Scheyltjens, I, Xia, Y, Trzebanski, S, Haimon, Z, Shemer, A, Lubart, A, Van Hove, H, Chappell-Maor, L, Boura-Halfon, S, Movahedi, K, Blinder, P, Jung, S.
A Binary Cre Transgenic Approach Dissects Microglia and CNS Border-Associated Macrophages
Immunity 54, 176-190, 2021. (Epub 2020 Dec 16)

Kiss, M, Vande Walle, L, Saavedra, PHV, Lebegge, E, Van Damme, H, Murgaski, A, Qian, J, Ehling, M, Pretto, S, Bolli, E, Keirsse, J, Bardet, PMR, Arnouk, SM, Elkrim, Y, Schmoetten, M, Brughmans, J, Debraekeleer, A, Fossoul, A, Boon, L, et al..
IL1beta Promotes Immune Suppression in the Tumor Microenvironment Independent of the Inflammasome and Gasdermin D
Cancer Immunol Res 9, 309-323, 2021. (Epub 2020 Dec 23)

Klionsky, DJ, Abdel-Aziz, AK, Abdelfatah, S, Abdellatif, M, Abdoli, A, Abel, S, Abeliovich, H, Abildgaard, MH, Abudu, YP, Acevedo-Arozena, A, Adamopoulos, IE, Adeli, K, Adolph, TE, Adornetto, A, Aflaki, E, Agam, G, Agarwal, A, Aggarwal, BB, Agnello, M, et al..
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Autophagy 1, 1-382, 2021. (Epub 2021 Feb 8)

Kremer, A, Van Hamme, E, Bonnardel, J, Borghgraef, P, Guérin, C, Guilliams, M, Lippens, S.
A workflow for 3D-CLEM investigating liver tissue
J Microsc 281, 231-242, 2021. (Epub 2020 Oct 9)

Lahmar, Q, Schouppe, E, Morias, Y, Van Overmeire, E, De Baetselier, P, Movahedi, K, Laoui, D, Sarukhan, A, Van Ginderachter, JA.
Monocytic myeloid-derived suppressor cells home to tumor-draining lymph nodes via CCR2 and locally modulate the immune response
Cell Immunol 362, 104296, 2021. (Epub 2021 Jan 30)

Landewe, RB, Gensler, LS, Poddubnyy, D, Rahman, P, Hojnik, M, Li, X, Liu Leage, S, Adams, D, Carlier, H, Van den Bosch, F, group, C-Ys.
Continuing versus withdrawing ixekizumab treatment in patients with axial spondyloarthritis who achieved remission: efficacy and safety results from a placebo-controlled, randomised withdrawal study (COAST-Y)
Ann Rheum Dis 80, 1022-1030, 2021. (Epub 2021 May 6)

Lasierra Losada, M, Pauler, M, Vandamme, N, Goossens, S, Berx, G, Leppkes, M, Schuhwerk, H, Brabletz, S, Brabletz, T, Stemmler, MP.
Pancreas morphogenesis and homeostasis depends on tightly regulated Zeb1 levels in epithelial cells
Cell Death Discov 7, 138, 2021. (Epub 2021 Jun 11)

Lecocq, Q, Awad, RM, De Vlaeminck, Y, De Mey, W, Ertveldt, T, Goyvaerts, C, Raes, G, Thielemans, K, Keyaerts, M, Devoogdt, N, Breckpot, K.
Single-Domain Antibody Nuclear Imaging Allows Noninvasive Quantification of LAG-3 Expression by Tumor-Infiltrating Leukocytes and Predicts Response of Immune Checkpoint Blockade
J Nucl Med 62, 1638-1644, 2021. (Epub 2021 Mar 12)

Lecocq, Q, Debie, P, Puttemans, J, Awad, RM, De Beck, L, Ertveldt, T, De Vlaeminck, Y, Goyvaerts, C, Raes, G, Keyaerts, M, Breckpot, K, Devoogdt, N.
Evaluation of single domain antibodies as nuclear tracers for imaging of the immune checkpoint receptor human lymphocyte activation gene-3 in cancer
EJNMMI Res 11, 115, 2021. (Epub 2021 Nov 2)

Le Naour, J, Liu, P, Zhao, L, Adjemian, S, Sztupinszki, Z, Taieb, J, Mulot, C, Silvin, A, Dutertre, CA, Ginhoux, F, et al., Vandenabeele, P, et al., Kroemer, G.
A TLR3 ligand reestablishes chemotherapeutic responses in the context of FPR1 deficiency
Cancer Discov 11, 408-423, 2021. (Epub 2020 Oct 12)

Lichawska-Cieslar, A, Konieczny, P, Szukala, W, Declercq, W, Fu, M, Jura, J.
Loss of keratinocyte Mcpip1 abruptly activates the IL-23/Th17 and Stat3 pathways in skin inflammation
Biochim Biophys Acta Mol Cell Res 1868, 118866, 2021. (Epub 2020 Sep 29)

Liechti, T, Weber, LM, Ashhurst, TM, Stanley, N, Prlic, M, Van Gassen, S, Mair, F.
An updated guide for the perplexed: cytometry in the high-dimensional era
Nat Immunol 22, 1190-1197, 2021. (Epub 2021 Oct)

Li, H, von Wangenheim, D, Zhang, X, Tan, S, Darwish-Miranda, N, Naramoto, S, Wabnik, K, De Rycke, R, Kaufmann, WA, Gutl, D, Tejos, R, Grones, P, Ke, M, Chen, X, Dettmer, J, Friml, J.
Cellular requirements for PIN polar cargo clustering in Arabidopsis thaliana
New Phytol 229, 351-369, 2021. (Epub 2020 Aug 18)

Llauger, G, Monti, D, Aduriz, M, Romao, E, Dumon, AD, Mattio, MF, Wigdorovitz, A, Muyldermans, S, Vincke, C, Parreno, V, Del Vas, M.
Development of Nanobodies against Mal de Rio Cuarto virus major viroplasm protein P9-1 for diagnostic sandwich ELISA and immunodetection
Sci Rep 11, 20013, 2021. (Epub 2021 Oct 8)

Lodder, C, Scheyltjens, I, Stancu, IC, Botella Lucena, P, Gutierrez de Rave, M, Vanherle, S, Vanmierlo, T, Cremers, N, Vanrusselt, H, Brone, B, Hanseeuw, B, Octave, JN, Bottelbergs, A, Movahedi, K, Dewachter, I.
CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia
Acta Neuropathol Commun 9, 108, 2021. (Epub 2021 Jun 8)

Lorenzi, L, Chiu, HS, Avila Cobos, F, Gross, S, Volders, PJ, Cannoodt, R, Nuytens, J, Vanderheyden, K, Anckaert, J, Lefever, S, Tay, AP, de Bony, EJ, Trypsteen, W, Gysens, F, Vromman, M, Goovaerts, T, Hansen, TB, Kuersten, S, Nijs, N, et al..
The RNA Atlas expands the catalog of human non-coding RNAs
Nat Biotechnol 39, 1467-1467, 2021. (Epub 2021 Jun 17)

Louwe, PA, Scott, CL.
Welcoming c-MAF to the macrophage transcription factor VAM-ily
Sci Immunol 6, eabl5793, 2021. (Epub 2021 Oct 1)

Lukasik, Z, Gracey, E, Venken, K, Ritchlin, C, Elewaut, D.
Crossing the boundaries: IL-23 and its role in linking inflammation of the skin, gut and joints
Rheumatology (Oxford) 60, iv16–iv27, 2021. (Epub 2021 May 7)

Lu, Z, Van Eeckhoutte, HP, Liu, G, Nair, PM, Jones, B, Gillis, CM, Nalkurthi, BC, Verhamme, F, Buyle-Huybrecht, T, Vandenabeele, P, Vanden Berghe, T, Brusselle, GG, Murphy, JM, Wark, PA, Bracke, KR, Fricker, M, Hansbro, PM.
Necroptosis Signalling Promotes Inflammation, Airway Remodelling and Emphysema in COPD
Am J Respir Crit Care Med 204, 667-681, 2021. (Epub 2021 Jun 16)

Mahony, CB, Cacialli, P, Pasche, C, Monteiro, R, Savvides, SN, Bertrand, JY.
Hapln1b, a central organizer of the ECM, modulates kit signaling to control developmental hematopoiesis in zebrafish
Blood Adv 5, 4935-4948, 2021. (Epub 2021 Dec 14)

Maifeld, A, Bartolomaeus, H, Lober, U, Avery, EG, Steckhan, N, Marko, L, Wilck, N, Hamad, I, Susnjar, U, Mahler, A, Hohmann, C, Chen, CY, Cramer, H, Dobos, G, Lesker, TR, Strowig, T, Dechend, R, Bzdok, D, Kleinewietfeld, M, et al..
Fasting alters the gut microbiome reducing blood pressure and body weight in metabolic syndrome patients
Nat Commun 12, 1970, 2021. (Epub 2021 Mar 30)

Maksymowych, WP, Claudepierre, P, de Hooge, M, Lambert, RG, Landewe, R, Molto, A, van der Heijde, D, Bukowski, JF, Jones, H, Pedersen, R, Szumski, A, Vlahos, B, Dougados, M.
Structural changes in the sacroiliac joint on MRI and relationship to ASDAS inactive disease in axial spondyloarthritis: a 2-year study comparing treatment with etanercept in EMBARK to a contemporary control cohort in DESIR
Arthritis Res Ther 23, 43, 2021. (Epub 2021 Jan 29)

Maksymowych, WP, Lambert, RG, Baraliakos, X, Weber, U, Machado, PM, Pedersen, SJ, de Hooge, M, Sieper, J, Wichuk, S, Poddubnyy, D, Rudwaleit, M, van der Heijde, D, Landewe, R, Eshed, I, Ostergaard, M.
Data-driven definitions for active and structural MRI lesions in the sacroiliac joint in spondyloarthritis and their predictive utility
Rheumatology (Oxford) 60, 4778-4789, 2021. (Epub 2021 Oct 2)

Martens, S, Bridelance, J, Roelandt, R, Vandenabeele, P, Takahashi, N.
MLKL in cancer: more than a necroptosis regulator
Cell Death Differ 28, 1757-1772, 2021. (Epub 2021 May 5)

Maschalidi, S, Ravichandran, KS.
Phagocytosis: Sweet Repulsions via the Glycocalyx
Curr Biol 31, R20-R22, 2021. (Epub 2021 Jan 11)

Mease, PJ, Lertratanakul, A, Anderson, JK, Papp, K, Van den Bosch, F, Tsuji, S, Dokoupilova, E, Keiserman, M, Wang, X, Zhong, S, McCaskill, RM, Zueger, P, Pangan, AL, Tillett, W.
Upadacitinib for psoriatic arthritis refractory to biologics: SELECT-PsA 2
Ann Rheum Dis 80, 312-320, 2021. (Epub 2020 Dec 3)

Mease, PJ, Lertratanakul, A, Papp, KA, van den Bosch, FE, Tsuji, S, Dokoupilova, E, Keiserman, MW, Bu, X, Chen, L, McCaskill, RM, Zueger, P, McDearmon-Blondell, EL, Pangan, AL, Tillett, W.
Upadacitinib in Patients with Psoriatic Arthritis and Inadequate Response to Biologics: 56-Week Data from the Randomized Controlled Phase 3 SELECT-PsA 2 Study
Rheumatol Ther 8, 903-919, 2021. (Epub 2021 Apr 28)

Mease, P, van den Bosch, F.
IL-23 and axial disease: do they come together?
Rheumatology (Oxford) 60, iv28-iv33, 2021. (Epub 2021 Oct 19)

Medina, CB, Chiu, YH, Stremska, ME, Lucas, CD, Poon, I, Tung, KS, Elliott, MR, Desai, B, Lorenz, UM, Bayliss, DA, Ravichandran, KS.
Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation
Immunity 54, 1715-1727, 2021. (Epub 2021 Aug 10)

Meireson, A, Tavernier, SJ, Van Gassen, S, Sundahl, N, Demeyer, A, Spaas, M, Kruse, V, Ferdinande, L, Van Dorpe, J, Hennart, B, Allorge, D, Haerynck, F, Decaestecker, K, Rottey, S, Saeys, Y, Ost, P, Brochez, L.
Immune Monitoring in Melanoma and Urothelial Cancer Patients Treated with Anti-PD-1 Immunotherapy and SBRT Discloses Tumor Specific Immune Signatures
Cancers (Basel) 13, 2630, 2021. (Epub 2021 May 27)

Meyts, I, Bucciol, G, Quinti, I, Neven, B, Fischer, A, Seoane, E, Lopez-Granados, E, Gianelli, C, Robles-Marhuenda, A, Jeandel, PY, Paillard, C, Sankaran, VG, Demirdag, YY, et al, Bosteels, C, Lambrecht, BN, et al..
Coronavirus Disease 2019 in patients with inborn errors of immunity: an international study
J Allergy Clin Immunol 147, 520-531, 2021. (Epub 2020 Sep 24)

Mody, D, Bouckaert, J, Savvides, SN, Gupta, V.
Rational Design and Development of HDAC Inhibitors for Breast Cancer Treatment
Curr Pharm Des 27, 4610-4629, 2021. (Epub 2021 Sep 17)

Mohamed, SMA, Wohlmann, A, Schofield, P, Sia, KCS, McCalmont, H, Savvides, SN, Verstraete, K, Kavallaris, M, Christ, D, Friedrich, KH, Bayat, N, Lock, RB.
A recombinant antibody fragment directed to the thymic stromal lymphopoietin receptor (CRLF2) efficiently targets pediatric Philadelphia chromosome-like acute lymphoblastic leukemia
Int J Biol Macromol 190, 214-223, 2021. (Epub 2021 Sep 2)

Molto, A, Lopez-Medina, C, Van den Bosch, FE, Boonen, A, Webers, C, Dernis, E, van Gaalen, FA, Soubrier, M, Claudepierre, P, Baillet, A, Starmans-Kool, M, Spoorenberg, A, Jacques, P, Carron, P, Joos, R, Lenaerts, J, Gossec, L, Pouplin, S, Ruyssen-Witrand, A, et al..
Efficacy of a tight-control and treat-to-target strategy in axial spondyloarthritis: results of the open-label, pragmatic, cluster-randomised TICOSPA trial
Ann Rheum Dis 80, 1436-1444, 2021. (Epub 2021 May 6)

Molto, A, van der Heijde, D, Van den Bosch, FE, Dougados, M.
Response to: 'Correspondence on 'Efficacy of a tight-control and treat-to-target strategy in axial spondyloarthritis: results of the open-label, pragmatic, cluster-randomised TICOSPA trial'' by Cai and Peng
Ann Rheum Dis , in press, 2021. (Epub 2021 Jun 29)

Naert, T, Tulkens, D, Van Nieuwenhuysen, T, Przybyl, J, Demuynck, S, van de Rijn, M, Al-Jazrawe, M, Alman, BA, Coucke, PJ, De Leeneer, K, Vanhove, C, Savvides, SN, Creytens, D, Vleminckx, K.
CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping
Proc Natl Acad Sci U S A 118, e2115116118, 2021. (Epub 2021 Nov 23)

Naesens, L, Smet, J, Tavernier, SJ, Schelstraete, P, Hoste, L, Lambrecht, S, Verhelst, H, van der Werff Ten Bosch, J, Ferster, A, Blumental, S, Hilbert, P, Kerre, T, Vande Walle, J, Licht, C, Roumenina, LT, Stordeur, P, Haerynck, F.
Plasma C3d levels as a diagnostic marker for complete complement factor I deficiency
J Allergy Clin Immunol 147, 749-753, 2021. (Epub 2020 Aug 24)

Nakamura, A, Zeng, F, Nakamura, S, Reid, KT, Gracey, E, Lim, M, Leng, L, Jo, S, Park, YS, Kusuda, M, Machhar, R, Boroojeni, SF, Wu, B, Rossomacha, E, Kim, TH, Ciccia, F, Rockel, JS, Kapoor, M, Inman, RD, et al..
Macrophage migration inhibitory factor drives pathology in a mouse model of spondyloarthritis and is associated with human disease
Sci Transl Med 13, eabg1210, 2021. (Epub 2021 Oct 20)

Nash, P, Kerschbaumer, A, Dorner, T, Dougados, M, Fleischmann, RM, Geissler, K, McInnes, I, Pope, JE, van der Heijde, D, Stoffer-Marx, M, Takeuchi, T, Trauner, M, Winthrop, KL, de Wit, M, Aletaha, D, Baraliakos, X, Boehncke, WH, Emery, P, Isaacs, JD, et al..
Points to consider for the treatment of immune-mediated inflammatory diseases with Janus kinase inhibitors: a consensus statement
Ann Rheum Dis 80, 71-87, 2021. (Epub 2020 Nov 6)

Oikonomou, N, Schuijs, MJ, Chatzigiagkos, A, Androulidaki, A, Aidinis, V, Hammad, H, Lambrecht, BN, Pasparakis, M.
Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation
Mucosal Immunol 14, 1160-1171, 2021. (Epub 2021 May 27)

Oltean, T, Van San, E, Divert, T, Vanden Berghe, T, Saelens, X, Maelfait, J, Takahashi, N, Vandenabeele, P.
Viral dosing of influenza A infection reveals involvement of RIPK3 and FADD, but not MLKL
Cell Death Dis 12, 471, 2021. (Epub 2021 May 11)

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