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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Delerive, P, De Bosscher, K, Besnard, S, Vanden Berghe, W, Peters, JM, Gonzalez, FJ, Fruchart, J-C, Tedgui, A, Haegeman, G, Staels, B. Peroxisome proliferator-activated receptor a negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kB and AP-1 J Biol Chem 274, 32048-32054, 1999. (Epub ---) 
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De Valck, D, Jin, D-Y, Heyninck, K, Van de Craen, M, Contreras, R, Fiers, W, Jeang, K-T, Beyaert, R. The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases Oncogene 18, 4182-4190, 1999. (Epub ---)
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Escalante-Ochoa, C, Ducatelle, R, Charlier, G, De Vos, K, Haesebrouck, F. Significance of host cell kinesin in the development of Chlamydia psittaci Infect Immun 67, 5441-5446, 1999. (Epub ---) 
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Eymin, B, Sordet, O, Droin, N, Munsch, B, Haugg, M, Van de Craen, M, Vandenabeele, P, Solary, E. Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity Oncogene 18, 4839-4847, 1999. (Epub ---)
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Faraco, PR, Ledgerwood, EC, Vandenabeele, P, Prins, JB, Bradley, JR. Tumor necrosis factor induces distinct patterns of caspase activation in WEHI-164 cells associated with apoptosis or necrosis depending on cell cycle stage Biochem Biophys Res Commun 261, 385-392, 1999. (Epub ---)
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Ferrari, D, Los, M, Bauer, MKA, Vandenabeele, P, Wesselborg, S, Schulze-Osthoff, K. P2Z purinoreceptor ligation induces activation of caspases with distinct roles in apoptotic and necrotic alterations of cell death FEBS Lett 447, 71-75, 1999. (Epub ---)
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Fiers, W, Beyaert, R, Declercq, W, Vandenabeele, P. More than one way to die: Apoptosis, necrosis and reactive oxygen damage Oncogene 18, 7719-7730, 1999. (Epub ---)
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Goossens, V, De Vos, K, Vercammen, D, Steemans, M, Vancompernolle, K, Fiers, W, Vandenabeele, P, Grooten, J. Redox regulation of TNF signaling BioFactors 10, 145-156, 1999. (Epub ---)
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Goossens, V, Stangé, G, Moens, K, Pipeleers, D, Grooten, J. Regulation of tumor necrosis factor-induced, mitochondria- and reactive oxygen species-dependent cell death by the electron flux through the electron transport chain complex I Antiox Redox Signal 1, 285-295, 1999. (Epub ---)
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Heyninck, K, Beyaert, R. The cytokine-inducible zinc finger protein A20 inhibits IL-1-induced NF-kB activation at the level of TRAF6 FEBS Lett 442, 147-150, 1999. (Epub ---)
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Heyninck, K, Denecker, G, De Valck, D, Fiers, W, Beyaert, R. Inhibition of tumor necrosis factor-induced necrotic cell death by the zinc finger protein A20 Anticancer Res 19, 2863-2868, 1999. (Epub ---)
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Heyninck, K, De Valck, D, Vanden Berghe, W, Van Criekinge, W, Contreras, R, Fiers, W, Haegeman, G, Beyaert, R. The zinc finger protein A20 inhibits TNF-induced NF-kB-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal and directly binds to a novel NF-kB-inhibiting protein ABIN J Cell Biol 145, 1471-1482, 1999. (Epub ---)
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Janssens, B, Staes, K, van Roy, F. Human alpha-catulin, a novel alpha-catenin-like molecule with conserved genomic structure, but deviating alternative splicing Biochim Biophys Acta 1447, 341-347, 1999. (Epub ---)
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Kools, P, Vanhalst, K, Van den Eynde, E, van Roy, F. The human cadherin-10 gene: Complete coding sequence, predominant expression in the brain, and mapping on chromosome 5p13-14 FEBS Lett 452, 328-334, 1999. (Epub ---)
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Kools, P, Vanhalst, K, van Roy, F. Assignment of cadherin-4 (R-cadherin, CDH4) to human chromosome band 20q13.3 Cytogenet Cell Genet 86, 26-27, 1999. (Epub ---)
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Laroy, W, Maras, M, Contreras, R. Structure-function analysis of human liver a2,6-sialyltransferase In Sialobiology and Other Novel Forms of Glycosylation. (Inoue, Y, Lee, YC, Troy II, FA, eds.), Osaka, Gakushin, pp. 183-186, 1999. (Epub ---)
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Levi, B, Sica, A, Müller-Newen, G, Takahashi, N, Vandenabeele, P, Fish, E. Jerusalem of cytokines Cytokine Growth Factor Rev 10, 159-171, 1999. (Epub ---)
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Libert, C, Wielockx, B, Grijalba, B, Van Molle, W, Kremmer, E, Colten, HR, Fiers, W, Brouckaert, P. The role of complement activation in tumour necrosis factor-induced lethal hepatitis Cytokine 11, 617-625, 1999. (Epub ---)
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Libert, C, Wielockx, B, Hammond, GL, Brouckaert, P, Fiers, W, Elliott, RW. Identification of a locus on distal mouse chromosome 12 that controls resistance to tumor necrosis factor-induced lethal shock Genomics 55, 284-289, 1999. (Epub ---)
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Li, CD, Berx, G, Larsson, C, Auer, G, Aspenblad, U, Pan, Y, Sundelin, B, Ekman, M, Nordenskjöld, M, van Roy, F, Bergerheim, USR. Distinct deleted regions on chromosome segment 16q23-24 associated with metastases in prostate cancer Gene Chromos Cancer 24, 175-182, 1999. (Epub ---)
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Louagie, H, Schotte, P, Vral, A, Cornelissen, M, Thierens, H, Beyaert, R, De Ridder, L, Philippé, J. Apoptosis induced by g irradiation in peripheral blood mononuclear cells is not mediated by cytochrome-c release and only partially involves caspase-3-like proteases Cell Biol Int 23, 611-617, 1999. (Epub ---)
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Machado, JC, Soares, P, Carneiro, F, Rocha, A, Beck, S, Blin, N, Berx, G, Sobrinho-Simões, M. E-cadherin gene mutations provide a genetic basis for the phenotypic divergence of mixed gastric carcinomas Lab Invest 79, 459-465, 1999. (Epub ---)
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Maras, M, De Bruyn, A, Vervecken, W, Uusitalo, J, Penttilä, M, Busson, R, Herdewijn, P, Contreras, R. In vivo synthesis of complex N-glycans by expression of human N-acetylglucosaminyltransferase I in the filamentous fungus Trichoderma reesei FEBS Lett 452, 365-370, 1999. (Epub ---)
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Maras, M, van Die, I, Contreras, R, van den Hondel, CAMJJ. Filamentous fungi as production organisms for glycoproteins of bio-medical interest Glycoconjugate J 16, 99-107, 1999. (Epub ---)
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Martinet, W, Van den Plas, D, Raes, H, Reekmans, R, Contreras, R. Bax-induced cell death in Pichia pastoris Biotechnol Lett 21, 821-829, 1999. (Epub ---)
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Mertens, N, Fiers, W, Remaut, E. An advanced vector system for high-level recombinant gene expression in Escherichia coli In Biotechnology International II. (Connor, TH, Weier, H-U, Fox, CF, eds.), San Francisco, Universal Medical Press, pp. 165-171, 1999. (Epub ---)
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Neirynck, S, Deroo, T, Saelens, X, Vanlandschoot, P, Min Jou, W, Fiers, W. A universal influenza A vaccine based on the extracellular domain of the M2 protein Nat Med 5, 1157-1163, 1999. (Epub ---)
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Nollet, F, Berx, G, van Roy, F. The role of the E-cadherin/catenin adhesion complex in the development and progression of cancer Mol Cell Biol Res Commun 2, 77-85, 1999. (Epub ---)
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Noë, V, Willems, J, Vandekerckhove, J, Van Roy, F, Bruyneel, E, Mareel, M. Inhibition of adhesion and induction of epithelial cell invasion by HAV-containing E-cadherin-specific peptides J Cell Sci 112, 127-135, 1999. (Epub ---)
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Pattyn, E, Van Ostade, X, Schauvliege, L, Verhee, A, Kalai, M, Vandekerckhove, J, Tavernier, J. Dimerization of the interferon type I receptor IFNaR2-2 is sufficient for induction of interferon effector genes but not for full antiviral activity J Biol Chem 274, 34838-34845, 1999. (Epub ---)
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Peppelenbosch, M, Boone, E, Jones, GE, van Deventer, SJH, Haegeman, G, Fiers, W, Grooten, J, Ridley, AJ. Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: Inhibition of Cdc42-mediated filopodium formation by TNF J Immunol 162, 837-845, 1999. (Epub ---)
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Peppelenbosch, MP, Desmedt, M, ten Hove, T, van Deventer, SJH, Grooten, J. Lipopolysaccharide regulates macrophage fluid phase pinocytosis via CD14-dependent and CD14-independent pathways Blood 93, 4011-4018, 1999. (Epub ---)
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Pynaert, G, Grooten, J, van Deventer, SJH, Peppelenbosch, MP. Cysteinyl leukotrienes mediate histamine hypersensitivity ex vivo by increasing histamine receptor numbers Mol Med 5, 685-692, 1999. (Epub ---)
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Remaut, E, Bliki, C, Iturizza, M, Keymeulen, K. Development of regulatable expression systems for cloned genes in cold-adapted prokaryotes In Biotechnological Applications of Cold-Adapted Organisms. (Margesin, R, Schinner, F, eds.), Berlin-Heidelberg-New York, Springer, pp. 1-16 , 1999. (Epub ---)
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Rickers, A, Peters, N, Badock, V, Beyaert, R, Vandenabeele, P, Dörken, B, Bommert, K. Cleavage of transcription factor SP1 by caspases during anti-IgM-induced B-cell apoptosis Eur J Biochem 261, 269-274, 1999. (Epub ---)
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Rottiers, P, Desmedt, M, Dooms, H, Contreras, R, Grooten, J. Tumoral environment triggers transcript anomalies in established tumors: Induction of altered gene expression and of aberrant, truncated and B2 repeat-containing gene transcripts Neoplasia 1, 557-567, 1999. (Epub ---)
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Saelens, X, Vanlandschoot, P, Martinet, W, Maras, M, Neirynck, S, Contreras, R, Fiers, W, Min Jou, W. Protection of mice against a lethal influenza virus challenge after immunization with yeast-derived secreted influenza virus hemagglutinin Eur J Biochem 260, 166-175, 1999. (Epub ---)
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Samowitz, WS, Powers, MD, Spirio, LN, Nollet, F, van Roy, F, Slattery, ML. beta-Catenin mutations are more frequent in small colorectal adenomas than in larger adenomas and invasive carcinomas Cancer Res 59, 1442-1444, 1999. (Epub ---)
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Schotte, P, Beyaert, R. A sensitizing function for lithium ions in tumor necrosis factor apoptosis In Lithium - 50 Years: Recent Advances in Biology and Medicine. (Lucas, KC, Becker, RW, Gallicchio, VS, eds.), Cheshire, Weidner Publishing Group, pp. 153-159, 1999. (Epub ---)
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Schotte, P, Declercq, W, Van Huffel, S, Vandenabeele, P, Beyaert, R. Non-specific effects of methyl ketone peptide inhibitors of caspases FEBS Lett 442, 117-121, 1999. (Epub ---)
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Takahashi, N, Waelput, W, Guisez, Y. Leptin is an endogenous protective protein against the toxicity exerted by tumor necrosis factor J Exp Med 189, 207-212, 1999. (Epub ---)
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Tejpar, S, Nollet, F, Li, C, Wunder, JS, Michils, G, dal Cin, P, Van Cutsem, E, Bapat, B, van Roy, F, Cassiman, JJ, Alman, BA. Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor) Oncogene 18, 6615-6620, 1999. (Epub ---)
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Van Criekinge, W, Beyaert, R. Yeast two-hybrid: State of the art Biol Proced Online (wwwscienceuwaterlooca/bpo) 2, 1-38, 1999. (Epub ---)
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Van Criekinge, W, Cornelis, S, Van de Craen, M, Vandenabeele, P, Fiers, W, Beyaert, R. GAL4 is a substrate for caspases: Implications for two-hybrid screening and other GAL4-based assays Mol Cell Biol Res Commun 1, 158-161, 1999. (Epub ---)
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Van de Craen, M, Berx, G, Van den brande, I, Fiers, W, Declercq, W, Vandenabeele, P. Proteolytic cleavage of beta-catenin by caspases: An in vitro analysis FEBS Lett 458, 167-170, 1999. (Epub ---)
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Van de Craen, M, Declercq, W, Van den brande, I, Fiers, W, Vandenabeele, P. The proteolytic procaspase activation network: An in vitro analysis Cell Death Differ 6, 1117-1124, 1999. (Epub ---)
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Van de Craen, M, De Jonghe, C, Van den brande, I, Declercq, W, Van Gassen, G, Van Criekinge, W, Vanderhoeven, I, Fiers, W, Van Broeckhoven, C, Hendriks, L, Vandenabeele, P. Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases FEBS Lett 445, 149-154, 1999. (Epub ---)
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Vanden Berghe, W, De Bosscher, K, Boone, E, Plaisance, S, Haegeman, G. The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter J Biol Chem 274, 32091-32098, 1999. (Epub ---)
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Vanden Berghe, W, Francesconi, E, De Bosscher, K, Resche-Rigon, M, Haegeman, G. Dissociated glucocorticoids with anti-inflammatory potential repress interleukin-6 gene expression by a nuclear factor-kB-dependent mechanism Mol Pharmacol 56, 797-806, 1999. (Epub ---)
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Van Gassen, G, De Jonghe, C, Pype, S, Van Criekinge, W, Julliams, A, Vanderhoeven, I, Woodrow, S, Beyaert, R, Huylebroeck, D, Van Broeckhoven, C. Alzheimer's disease associated presenilin 1 interacts with HC5 and ZETA, subunits of the catalytic 20S proteasome Neurobiol Dis 6, 376-391, 1999. (Epub ---)
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