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Mertens, N, Remaut, E, Fiers, W.
Tight transcriptional control mechanism ensures stable high-level expression from T7 promoter-based expression plasmids
Bio/Technology 13, 175-179, 1995. (Epub ---)

Mertens, N, Remaut, E, Fiers, W.
Versatile, multi-featured plasmids for high-level expression of heterologous genes in Escherichia coli: Overproduction of human and murine cytokines
Gene 164, 9-15, 1995. (Epub ---)

Nollet, F, van Hengel, J, Berx, G, Molemans, F, van Roy, F.
Isolation and characterization of a human pseudogene (CTNNAP1) for alpha-E-catenin (CTNNA1): Assignment of the pseudogene to 5q22 and the alpha-E-catenin gene to 5q31
Genomics 26, 410-413, 1995. (Epub ---)

Nyyssönen, E, Demolder, J, Contreras, R, Keränen, S, Penttilä, M.
Protein production by the filamentous fungus Trichoderma reesei: Secretion of active antibody molecules
Can J Bot 73, S885-S890, 1995. (Epub ---)

Robbens, J, Raeymaekers, A, Steidler, L, Fiers, W, Remaut, E.
Production of soluble and active recombinant murine interleukin-2 in Escherichia coli: High level expression, kil-induced release, and purification
Protein Expr Purif 6, 481-486, 1995. (Epub ---)

Steidler, L, Fiers, W, Remaut, E.
Simultaneous light emission from cloned Vibrio fischeri lux genes and expression of LamB or LamB-protein A fusion proteins in Escherichia coli depends on using a single chimeric operon
Biotechnol Bioengin 48, 667-672, 1995. (Epub ---)

Steidler, L, Wells, JM, Raeymaekers, A, Vandekerckhove, J, Fiers, W, Remaut, E.
Secretion of biologically active murine interleukin-2 by Lactococcus lactis subsp. lactis
Appl Environ Microbiol 61, 1627-1629, 1995. (Epub ---)

Takahashi, N, Brouckaert, P, Fiers, W.
Mechanism of tolerance to tumor necrosis factor: Receptor-specific pathway and selectivity
Am J Physiol 269, R398-R405, 1995. (Epub ---)

Takahashi, N, Fiers, W, Brouckaert, P.
Anti-tumor activity of tumor necrosis factor in combination with interferon-gamma is not affected by prior tolerization
Int J Cancer 63, 846-854, 1995. (Epub ---)

Vandenabeele, P, Declercq, W, Beyaert, R, Fiers, W.
Two tumour necrosis factor receptors: Structure and function
Trends Cell Biol 5, 392-399, 1995. (Epub ---)

Vandenabeele, P, Declercq, W, Vanhaesebroeck, B, Grooten, J, Fiers, W.
Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells
J Immunol 154, 2904-2913, 1995. (Epub ---)

van Hengel, J, Nollet, F, Berx, G, van Roy, N, Speleman, F, van Roy, F.
Assignment of the human beta-catenin gene (CTNNB1) to 3p22-p21.3 by fluorescence in situ hybridization
Cytogenet Cell Genet 70, 68-70, 1995. (Epub ---)

Vanlandschoot, P, Beirnaert, E, Dewilde, S, Saelens, X, Bestebroer, T, de Jong, J, Min Jou, W, Fiers, W.
A fairly conserved epitope on the hemagglutinin of influenza A (H3N2) virus with variable accessibility to neutralizing antibody
Virology 212, 526-534, 1995. (Epub ---)

Vercammen, D, Vandenabeele, P, Declercq, W, Van de Craen, M, Grooten, J, Fiers, W.
Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF
Cytokine 7, 463-470, 1995. (Epub ---)

Vermeulen, S, Bruyneel, E, van Roy, F, Mareel, M, Bracke, M.
Activation of the E-cadherin/catenin complex in human MCF-7 breast cancer cells by all-trans-retinoic acid
Br J Cancer 72, 1447-1453, 1995. (Epub ---)

Vermeulen, SJ, Bruyneel, EA, Bracke, ME, De Bruyne, GK, Vennekens, KM, Vleminckx, KL, Berx, GJ, van Roy, FM, Mareel, MM.
Transition from the noninvasive to the invasive phenotype and loss of alpha-catenin in human colon cancer cells
Cancer Res 55, 4722-4728, 1995. (Epub ---)

Westermarck, J, Häkkinen, L, Fiers, W, Kähäri, V-M.
TNF-R55-specific form of human tumor necrosis factor-alpha induces collagenase gene expression by human skin fibroblasts
J Invest Dermatol 105, 197-202, 1995. (Epub ---)

Barbara, JAJ, Smith, WB, Gamble, JR, Van Ostade, X, Vandenabeele, P, Tavernier, J, Fiers, W, Vadas, MA, Lopez, AF.
Dissociation of TNF-a cytotoxic and proinflammatory activities by p55 receptor- and p75 receptor-selective TNF-a mutants
EMBO J 13, 843-850, 1994. (Epub ---)

Beyaert, R, Fiers, W.
Molecular mechanisms of tumor necrosis factor-induced cytotoxicity: What we do understand and what we do not
FEBS Lett 340, 9-16, 1994. (Epub ---)

Bracke, ME, Vermeulen, SJ, Bruyneel, EA, Vennekens, KM, De Bruyne, GK, van Roy, FM, Mareel, MM.
The invasion suppressor function of E-cadherin in mammary epithelioid cells
In Prospects in Diagnosis and Treatment of Breast Cancer. (Schmitt, M, ed.), Excerpta Medica International Congress Series, Amsterdam, Elsevier, pp. 107-115, 1994. (Epub ---)

Brouckaert, P, Ameloot, P, Cauwels, A, Everaerdt, B, Libert, C, Takahashi, N, Van Molle, W, Fiers, W.
Receptor-selective mutants of tumour necrosis factor in the therapy of cancer: Preclinical studies
Circ Shock 43, 185-190, 1994. (Epub ---)

Carter, AT, Narbad, A, Pearson, BM, Beck, K-F, Baum, B, Logghe, M, Contreras, R, Schweizer, M.
Phosphoribosylpyrophosphate synthetase (PRS): A new gene family in Saccharomyces cerevisiae
Yeast 10, 1031-1044, 1994. (Epub ---)

Demolder, J, Fiers, W, Contreras, R.
Human interferon-beta, expressed in Saccharomyces cerevisiae, is predominantly directed to the vacuoles. Influence of modified co-expression of secretion factors and chaperones
J Biotechnol 32, 179-189, 1994. (Epub ---)

De Sutter, K, Fiers, W.
A bifunctional murine::human chimeric antibody with one antigen-binding arm replaced by bacterial beta-lactamase
Mol Immunol 31, 261-267, 1994. (Epub ---)

De Sutter, K, Hostens, K, Vandekerckhove, J, Fiers, W.
Production of enzymatically active rat protein disulfide isomerase in Escherichia coli
Gene 141, 163-170, 1994. (Epub ---)

Dimanche-Boitrel, MT, Vakaet Jr., L, Pujuguet, P, Chauffert, B, Martin, MS, Hammann, A, Van Roy, F, Mareel, M, Martin, F.
In vivo and in vitro invasiveness of a rat colon cancer cell line maintaining E-cadherin expression: An enhancing role of tumor-associated myofibroblasts
Int J Cancer 56, 512-521, 1994. (Epub ---)

Donckier, V, Abramowicz, D, Bruyns, C, Florquin, S, Vanderhaegen, M-L, Amraoui, Z, Dubois, C, Vandenabeele, P, Goldman, M.
IFN-g prevents Th2 cell-mediated pathology after neonatal injection of semiallogenic spleen cells in mice
J Immunol 153, 2361-2368, 1994. (Epub ---)

Donckier, V, Flament, V, Gérard, C, Abramowicz, D, Vandenabeele, P, Wissing, M, Delvaux, A, Fiers, W, Leo, O, Velu, T, Goldman, M.
Modulation of the release of cytokines and reduction of the shock syndrome induced by anti-CD3 monoclonal antibody in mice by interleukin-10
Transplantation 57, 1436-1439, 1994. (Epub ---)

Everaerdt, B, Brouckaert, P, Fiers, W.
Recombinant IL-1 receptor antagonist protects against TNF-induced lethality in mice
J Immunol 152, 5041-5049, 1994. (Epub ---)

Feldmann, H, Aigle, M, Aljinovic, G, André, B, Baclet, MC, Barthe, C, Baur, A, Bécam, A-M, Biteau, N, Boles, E, Brandt, T, Brendel, M, Brückner, M, Bussereau, F, Christiansen, C, Contreras, R, Crouzet, M, Cziepluch, C, Démolis, N, et al..
Complete DNA sequence of yeast chromosome II
EMBO J 13, 5795-5809, 1994. (Epub ---)

Flamand, V, Donckier, V, Abramowicz, D, Goldman, M, Vandenabeele, P, Urbain, J, Moser, M, Leo, O.
In vivo immunosuppression induced by a weakly mitogenic antibody to mouse CD3: Evidence that induction of long-lasting in vivo unresponsiveness requires TcR signaling
Cell Immunol 157, 239-248, 1994. (Epub ---)

Goldman, GH, Vasseur, V, Contreras, R, Van Montagu, M.
Sequence analysis and expression studies of a gene encoding a novel serine + alanine-rich protein in Trichoderma harzianum
Gene 144, 113-117, 1994. (Epub ---)

Libert, C, Brouckaert, P, Fiers, W.
Protection by a1-acid glycoprotein against tumor necrosis factor-induced lethality
J Exp Med 180, 1571-1575, 1994. (Epub ---)

Libert, C, Takahashi, N, Cauwels, A, Brouckaert, P, Bluethmann, H, Fiers, W.
Response of interleukin-6-deficient mice to tumor necrosis factor-induced metabolic changes and lethality
Eur J Immunol 24, 2237-2242, 1994. (Epub ---)

Logghe, M, Molemans, F, Fiers, W, Contreras, R.
The two genes encoding yeast ribosomal protein S8 reside on different chromosomes, and are closely linked to the hsp70 stress protein genes SSA3 and SSA4
Yeast 10, 1093-1100, 1994. (Epub ---)

Marchant, A, Bruyns, C, Vandenabeele, P, Abramowicz, D, Gérard, C, Delvaux, A, Ghezzi, P, Velu, T, Goldman, M.
The protective role of interleukin-10 in endotoxin shock
Prog Clin Biol Res 388, 417-423, 1994. (Epub ---)

Marchant, A, Bruyns, C, Vandenabeele, P, Ducarme, M, Gérard, C, Delvaux, A, De Groote, D, Abramowicz, D, Velu, T, Goldman, M.
Interleukin-10 controls interferon-gamma and tumor necrosis factor production during experimental endotoxemia
Eur J Immunol 24, 1167-1171, 1994. (Epub ---)

Mareel, M, Bracke, M, Van Roy, F.
Invasion promoter versus invasion suppressor molecules: the paradigm of E-cadherin
Mol Biol Rep 19, 45-67, 1994. (Epub ---)

Mareel, MM, Vleminckx, K, Vermeulen, S, Gao, Y, Bracke, M, van Roy, F.
Downregulation in vivo of the invasion-suppressor molecule E-cadherin in experimental and clinical cancer
In Proceedings of the 24th International Symposium of the Princess Takamatsu Cancer Research Fund. Princeton, The Princeton Scientific Publishing Co., pp. 63-80 , 1994. (Epub ---)

Mareel, M, Van Roy, F, De Baetselier, P, Vakaet, L.
Invasiveness in development and neoplasia
In Developmental Biology and Cancer. (Hodges, GM, Rowlatt, C, eds.), New Jersey, The Telford Press, pp. 389-416, 1994. (Epub ---)

Steidler, L, Fiers, W, Remaut, E.
Efficient specific release of periplasmic proteins from Escherichia coli using temperature induction of cloned kil gene of pMB9
Biotechnol Bioeng 44, 1074-1082, 1994. (Epub ---)

Takahashi, N, Brouckaert, P, Bemelmans, MHA, Buurman, WA, Fiers, W.
Mechanism of induction of tolerance to tumour necrosis factor (TNF): No involvement of modulators of TNF bioavailability or receptor binding
Cytokine 6, 235-242, 1994. (Epub ---)

Vandenabeele, P, Goossens, V, Beyaert, R, Declercq, W, Grooten, J, Vanhaesebroeck, B, Van de Craen, M, Vercammen, D, Depuydt, B, Denecker, G, Fiers, W.
Functional requirement of the two TNF receptors for induction of apoptosis in PC60 cells and the role of mitochondria in TNF-induced cytotoxicity
Circ Shock 44, 196-200, 1994. (Epub ---)

Vandenbossche, GMR, De Bruyne, GK, Bruyneel, EA, Clemminck, G, Vleminckx, K, van Roy, FM, Mareel, MM.
Microencapsulation of MDCK-ras-e cells prevents loss of the E-cadherin invasion suppressor function in vivo
Int J Cancer 57, 73-80, 1994. (Epub ---)

Vanhoenacker, P, Fiers, W, Haegeman, G.
Studies on the induction of the interleukin-6 promoter in cell lines of human and simian origin
Eur Cytokine Netw 5, 283-291, 1994. (Epub ---)

Van Ostade, X, Tavernier, J, Fiers, W.
Structure-activity studies of human tumour necrosis factors
Protein Eng 7, 5-22, 1994. (Epub ---)

Van Ostade, X, Vandenabeele, P, Tavernier, J, Fiers, W.
Human tumor necrosis factor mutants with preferential binding to and activity on either the R55 or R75 receptor
Eur J Biochem 220, 771-779, 1994. (Epub ---)

Vleminckx, KL, Deman, JJ, Bruyneel, EA, Van den Bossche, GMR, Keirsebilck, AA, Mareel, MM, van Roy, FM.
Enlarged cell-associated proteoglycans abolish E-cadherin functionality in invasive tumor cells
Cancer Res 54, 873-877, 1994. (Epub ---)

Behrens, J, Vakaet, L, Friis, R, Winterhager, E, van Roy, F, Mareel, MM, Birchmeier, W.
Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-src gene
J Cell Biol 120, 757-766, 1993. (Epub ---)

Beyaert, R, Heyninck, K, De Valck, D, Boeykens, F, Van Roy, F, Fiers, W.
Enhancement of tumor necrosis factor cytotoxicity by lithium chloride is associated with increased inositol phosphate accumulation
J Immunol 151, 291-300, 1993. (Epub ---)

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