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Grooten, J, Leroux-Roels, G, Fiers, W.
Specific suppression elicited by EL4 lymphoma cells in syngeneic mice. Specificity includes self-antigens on EL4
Eur J Immunol 17, 605-611, 1987. (Epub ---)

Hepburn, A, Boeynaems, JM, Fiers, W, Dumont, JE.
Modulation of tumor necrosis factor-alpha cytotoxicity in L929 cells by bacterial toxins, hydrocortisone and inhibitors of arachidonic acid metabolism
Biochem Biophys Res Commun 149, 815-822, 1987. (Epub ---)

Kettelhut, IC, Fiers, W, Goldberg, AL.
The toxic effects of tumor necrosis factor in vivo and their prevention by cyclooxygenase inhibitors
Proc Natl Acad Sci USA 84, 4273-4277, 1987. (Epub ---)

Krief, P, Boucheix, C, Billard, C, Mishal, Z, Van Agthoven, A, Fiers, W, Azzarone, B.
Modulation of expression of class II histocompatibility antigens by secretion of a cellular inhibitor in K562 leukemic cells
Eur J Immunol 17, 1021-1025, 1987. (Epub ---)

Kruys, V, Wathelet, M, Poupart, P, Contreras, R, Fiers, W, Content, J, Huez, G.
The 3' untranslated region of the human interferon-beta mRNA has an inhibitory effect on translation
Proc Natl Acad Sci USA 84, 6030-6034, 1987. (Epub ---)

Kurt-Jones, EA, Fiers, W, Pober, JS.
Membrane interleukin 1 induction on human endothelial cells and dermal fibroblasts
J Immunol 139, 2317-2324, 1987. (Epub ---)

Leemans, R, Remaut, E, Fiers, W.
A broad-host range expression vector based on the pL promoter of coliphage lambda: Regulated synthesis of human interleukin 2 in Erwinia and Serratia species
J Bacteriol 169, 1899-1904, 1987. (Epub ---)

Leroux-Roels, G, Grooten, J, Fiers, W.
Alloinduced suppression and cytotoxicity: Two functions of a single cell
Immunol Lett 15, 59-65, 1987. (Epub ---)

Malkovsky, M, Loveland, B, North, M, Asherson, GL, Gao, L, Ward, P, Fiers, W.
Recombinant interleukin-2 directly augments the cytotoxicity of human monocytes
Nature 325, 262-265, 1987. (Epub ---)

Mareel, MM, Van Roy, F, Messiaen, L, Bracke, M, Boghaert, E, Coopman, P.
Investigation of tumour-invasion mechanisms
In Cells, Membranes, and Disease, Including Renal. (Reid, E, Cook, GMW, Luzio, JP, eds.), Methodological Surveys in Biochemistry and Analysis, Vol. 17, New York-London, Plenum Press, pp. 359-370, 1987. (Epub ---)

Mareel, MM, van Roy, FM, Messiaen, LM, Boghaert, ER, Bruyneel, EA.
Qualitative and quantitative analysis of tumor invasion in vivo and in vitro
J Cell Sci Suppl. 8, 141-163, 1987. (Epub ---)

Mareel, M, Van Roy, F, Bruyneel, E, Bolscher, J, Schallier, D, De Mets, M.
Molecular biology of minimal invasion
Rec Res Cancer Res 106, 14-20, 1987. (Epub ---)

Marquet, RL, IJzermans, JNM, de Bruin, RWF, Fiers, W, Jeekel, J.
Anti-tumor activity of recombinant mouse tumor necrosis factor (TNF) on colon cancer in rats is promoted by recombinant rat interferon gamma; toxicity is reduced by indomethacin
Int J Cancer 40, 550-553, 1987. (Epub ---)

Messadi, DV, Pober, JS, Fiers, W, Gimbrone, MA, Murphy, GF.
Induction of an activation antigen on postcapillary venular endothelium in human skin organ culture
J Immunol 139, 1557-1562, 1987. (Epub ---)

Mueller, W, Vandenabeele, P.
A T cell clone which responds to interleukin 2 but not to interleukin 4
Eur J Immunol 17, 579-580, 1987. (Epub ---)

Plaetinck, G, Declercq, W, Tavernier, J, Nabholz, M, Fiers, W.
Recombinant tumor necrosis factor can induce interleukin 2 receptor expression and cytolytic activity in a rat x mouse T cell hybrid
Eur J Immunol 17, 1835-1838, 1987. (Epub ---)

Pober, JS, Lapierre, LA, Stolpen, AH, Brock, TA, Springer, TA, Fiers, W, Bevilacqua, MP, Mendrick, DL, Gimbrone, MA.
Activation of cultured human endothelial cells by recombinant lymphotoxin: Comparison with tumor necrosis factor and interleukin 1 species
J Immunol 138, 3319-3324, 1987. (Epub ---)

Podo, F, Carpinelli, G, Di Vito, M, Giannini, M, Proietti, E, Fiers, W, Gresser, I, Belardelli, F.
Nuclear magnetic resonance analysis of tumor necrosis factor-induced alterations of phospholipid metabolites and pH in Friend leukemia cell tumors and fibrosarcomas in mice
Cancer Res 47, 6481-6489, 1987. (Epub ---)

Poupart, P, Vandenabeele, P, Cayphas, S, Van Snick, J, Haegeman, G, Kruys, V, Fiers, W, Content, J.
B cell growth modulating and differentiating activity of recombinant human 26-kd protein (BSF-2, HuIFN-b2, HPGF)
EMBO J 6, 1219-1224, 1987. (Epub ---)

Proietti, E, Belardelli, F, Carpinelli, G, De Vito, M, Gresser, I, Fiers, W, Podo, F.
Interferon and tumor necrosis factor alter the phospholipid metabolism in Friend leukemia cell tumors in mice
In The Biology of the Interferon System 1986. (Cantell, K, Schellekens, H, eds.), Dordrecht-Boston-Lancaster, Martinus Nijhoff Publishers, pp. 281-285, 1987. (Epub ---)

Remaut, E, Marmenout, A, Simons, G, Fiers, W.
Expression of heterologous unfused protein in Escherichia coli
Methods Enzymol 153, 416-431, 1987. (Epub ---)

Roubin, R, Elsas, PP, Fiers, W, Dessein, AJ.
Recombinant human tumour necrosis factor rTNF enhances leukotriene biosynthesis in neutrophils and eosinophils stimulated with the Ca2+ ionophore A23187
Clin Exp Immunol 70, 484-490, 1987. (Epub ---)

Suffys, P, Beyaert, R, Van Roy, F, Fiers, W.
Reduced tumour necrosis factor-induced cytotoxicity by inhibitors of the arachidonic acid metabolism
Biochem Biophys Res Commun 149, 735-743, 1987. (Epub ---)

Taverne, J, Tavernier, J, Fiers, W, Playfair, JHL.
Recombinant tumour necrosis factor inhibits malaria parasites in vivo but not in vitro
Clin Exp Immunol 67, 1-4, 1987. (Epub ---)

Tavernier, J, Fransen, L, Marmenout, A, Van der Heyden, J, Müller, R, Ruysschaert, MR, Van Vliet, A, Bauden, R, Fiers, W.
Isolation and expression of the genes coding for mouse and human tumor necrosis factor (TNF) and biological properties of recombinant TNF
In Molecular Cloning and Analysis of Lymphokines. (Webb, DR, Goeddel, DV, eds.), Lymphokines, (Webb, DR, Goeddel, DV, eds.), Lymphokines, Vol. 13, Orlando, Academic Press, pp. 181-198, 1987. (Epub ---)

Van Emmelo, J, Ameloot, P, Fiers, W.
Expression in plants of the cloned satellite tobacco necrosis virus genome and of derived insertion mutants
Virology 157, 480-487, 1987. (Epub ---)

Abbud-Filho, M, Ransil, BJ, Kelley, VE, Fiers, W, Strom, TB.
Natural killer cell response to interferons
Clin Immunol Immunopathol 39, 264-276, 1986. (Epub ---)

Balkwill, FR, Lee, A, Aldam, G, Moodie, E, Thomas, JA, Tavernier, J, Fiers, W.
Human tumor xenografts treated with recombinant human tumor necrosis factor alone or in combination with interferons
Cancer Res 46, 3990-3993, 1986. (Epub ---)

Bevilacqua, MP, Pober, JS, Majeau, GR, Fiers, W, Cotran, RS, Gimbrone, MA.
Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: Characterization and comparison with the actions of interleukin 1
Proc Natl Acad Sci USA 83, 4533-4537, 1986. (Epub ---)

Brouckaert, PGG, Leroux-Roels, GG, Guisez, Y, Tavernier, J, Fiers, W.
In vivo anti-tumour activity of recombinant human and murine TNF, alone and in combination with murine IFN-gamma, on a syngeneic murine melanoma
Int J Cancer 38, 763-769, 1986. (Epub ---)

Collins, T, Lapierre, LA, Fiers, W, Strominger, JL, Pober, JS.
Recombinant human tumor necrosis factor increases mRNA levels and surface expression of HLA-A,B antigens in vascular endothelial cells and dermal fibroblasts in vitro
Proc Natl Acad Sci USA 83, 446-450, 1986. (Epub ---)

Degrave, W, Simons, G, Devos, R, Plaetinck, G, Remaut, E, Tavernier, J, Fiers, W.
Cloning and structure of a mouse interleukin-2 chromosomal gene
Mol Biol Rep 11, 57-61, 1986. (Epub ---)

Fiers, W.
The future role in medicine of proteins made by genetic engineering
In Biotechnology: Potentials and Limitations. (Silver, S, ed.), Dahlem Workshop Reports, Vol. 35, Berlin, Springer Verlag, pp. 165-177, 1986. (Epub ---)

Fiers, W, Ameloot, P, Van Emmelo, J.
Satellite tobacco necrosis virus: A new vector in plant genetic engineering
Symbiosis 2, 35-41, 1986. (Epub ---)

Fiers, W, Brouckaert, P, Devos, R, Fransen, L, Leroux-Roels, G, Remaut, E, Suffys, P, Tavernier, J, Van der Heyden, J, Van Roy, F.
Lymphokines and monokines in anti-cancer therapy
Cold Spring Harbor Symp Quant Biol 51, 587-595, 1986. (Epub ---)

Fiers, W, Brouckaert, P, Guisez, Y, Remaut, E, Van Roy, F, Devos, R, Fransen, L, Leroux-Roels, G, Marmenout, A, Tavernier, J, Van der Heyden, J.
Recombinant interferon g and its synergism with tumor necrosis factor in the human and mouse systems
In The Biology of the Interferon System 1985. (Schellekens, H, Stewart II, WE, eds.), Amsterdam-New York-Oxford, Elsevier Science Publishers, pp. 241-248, 1986. (Epub ---)

Fransen, L, Ruysschaert, MR, Van der Heyden, J, Fiers, W.
Recombinant tumor necrosis factor: Species specificity for a variety of human and murine transformed cell lines
Cell Immunol 100, 260-267, 1986. (Epub ---)

Fransen, L, Van der Heyden, J, Ruysschaert, R, Fiers, W.
Recombinant tumor necrosis factor: Its effect and its synergism with interferon-gamma on a variety of normal and transformed human cell lines
Eur J Cancer Clin Oncol 22, 419-426, 1986. (Epub ---)

Gresser, I, Belardelli, F, Tavernier, J, Fiers, W, Podo, F, Federico, M, Carpinelli, G, Duvillard, P, Prade, M, Maury, C, Bandu, MT, Maunoury, MT.
Anti-tumor effects of interferon in mice injected with interferon-sensitive and interferon-resistant Friend leukemia cells. V. Comparisons with the action of tumor necrosis factor
Int J Cancer 38, 771-778, 1986. (Epub ---)

Haegeman, G, Content, J, Volckaert, G, Derynck, R, Tavernier, J, Fiers, W.
Structural analysis of the sequence coding for an inducible 26-kDa protein in human fibroblasts
Eur J Biochem 159, 625-632, 1986. (Epub ---)

Kirstein, M, Fiers, W, Baglioni, C.
Growth inhibition and cytotoxicity of tumor necrosis factor in L929 cells is enhanced by high cell density and inhibition of mRNA synthesis
J Immunol 137, 2277-2280, 1986. (Epub ---)

Leroux-Roels, G, Fiers, W.
Genetische manipulatie in de toekomst
Annales Collegii Medici Antverpiensis 40, 273-280, 1986. (Epub ---)

Leung, DYM, Geha, RS, Newburger, JW, Burns, JC, Fiers, W, Lapierre, LA, Pober, JS.
Two monokines, interleukin 1 and tumor necrosis factor, render cultured vascular endothelial cells susceptible to lysis by antibodies circulating during Kawasaki syndrome
J Exp Med 164, 1958-1972, 1986. (Epub ---)

Müller, R, Marmenout, A, Fiers, W.
Synthesis and maturation of recombinant human tumor necrosis factor in eukaryotic systems
FEBS Lett 197, 99-104, 1986. (Epub ---)

Mareel, MM, van Roy, FM.
Are oncogenes involved in invasion and metastasis?
Anticancer Res 6, 419-436, 1986. (Epub ---)

Michiels, L, van Roy, FM, de Saint-Georges, L, Merregaert, J.
Genome organisation of the FBR-osteosarcoma virus complex: Identification of a subgenomic fos-specific message
Virus Res 5, 11-26, 1986. (Epub ---)

Mutsaers, JHGM, Kamerling, JP, Devos, R, Guisez, Y, Fiers, W, Vliegenthart, JFG.
Structural studies of the carbohydrate chains of human gamma-interferon
Eur J Biochem 156, 651-654, 1986. (Epub ---)

Pober, JS, Bevilacqua, MP, Mendrick, DL, Lapierre, LA, Fiers, W, Gimbrone, MA.
Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells
J Immunol 136, 1680-1687, 1986. (Epub ---)

Pober, JS, Gimbrone, MA, Lapierre, LA, Mendrick, DL, Fiers, W, Rothlein, R, Springer, TA.
Overlapping patterns of activation of human endothelial cells by interleukin 1, tumor necrosis factor, and immune interferon
J Immunol 137, 1893-1896, 1986. (Epub ---)

Remaut, E, Stanssens, P, Simons, G, Fiers, W.
Use of the phage lambda PL promoter for high-level expression of human interferons in Escherichia coli
Methods Enzymol 119, 366-375, 1986. (Epub ---)

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