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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Steidler, L, Remaut, E, Fiers, W. Pap pili as a vector system for surface exposition of an immunoglobulin G-binding domain of protein A of Staphylococcus aureus in Escherichia coli J Bacteriol 175, 7639-7643, 1993. (Epub ---) 
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Takahashi, N, Brouckaert, P, Fiers, W. Cyclooxygenase inhibitors prevent the induction of tolerance to the toxic effects of tumor necrosis factor J Immunother 14, 16-21, 1993. (Epub ---)
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Vandenabeele, P, Abramowicz, D, Berus, D, Van der Heyden, J, Grooten, J, Donckier, V, Hooghe-Peters, EL, Goldman, M, Fiers, W. Increased IL-6 production and IL-6-mediated Ig secretion in murine host-vs-graft disease J Immunol 150, 4179-4187, 1993. (Epub ---)
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Vanhaesebroeck, B, Reed, JC, De Valck, D, Grooten, J, Miyashita, T, Tanaka, S, Beyaert, R, Van Roy, F, Fiers, W. Effect of bcl-2 proto-oncogene expression on cellular sensitivity to tumor necrosis factor-mediated cytotoxicity Oncogene 8, 1075-1081, 1993. (Epub ---)
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Vanlandschoot, P, Maertens, G, Min Jou, W, Fiers, W. Recombinant secreted haemagglutinin protects mice against a lethal challenge of influenza virus Vaccine 11, 1185-1187, 1993. (Epub ---) 
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Van Ostade, X, Vandenabeele, P, Everaerdt, B, Loetscher, H, Gentz, R, Brockhaus, M, Lesslauer, W, Tavernier, J, Brouckaert, P, Fiers, W. Human TNF mutants with selective activity on the p55 receptor Nature 361, 266-269, 1993. (Epub ---)
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Yue-xin, L, Roggen, E, Min Jou, W, Fiers, W. Expression of neuraminidase of influenza virus in insect cells Chin J Biochem Biophys 25, 237-241, 1993. (Epub ---)
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Beyaert, R, Fiers, W. Potentiation of tumour necrosis factor-mediated activities by lithium salts: A review Lithium 3, 181-189, 1992. (Epub ---)
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Beyaert, R, Schulze-Osthoff, K, Van Roy, F, Fiers, W. Synergistic induction of interleukin-6 by tumor necrosis factor and lithium chloride in mice: Possible role in the triggering and exacerbation of psoriasis by lithium treatment Eur J Immunol 22, 2181-2184, 1992. (Epub ---)
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Brouckaert, P, Everaerdt, B, Fiers, W. The glucocorticoid antagonist RU38486 mimics interleukin-1 in its sensitization to the lethal and interleukin-6-inducing properties of tumor necrosis factor Eur J Immunol 22, 981-986, 1992. (Epub ---)
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Brouckaert, PGG, Fiers, W, Lejeune, FJ. Coley's vaccine and TNF therapy Nature 358, 630, 1992. (Epub ---)
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Brouckaert, P, Libert, C, Everaerdt, B, Fiers, W. Selective species specificity of tumor necrosis factor for toxicity in the mouse Lymphokine Cytokine Res 11, 193-196, 1992. (Epub ---)
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Demolder, J, Fiers, W, Contreras, R. Efficient synthesis of secreted murine interleukin-2 by Saccharomyces cerevisiae: Influence of 3'-untranslated regions and codon usage Gene 111, 207-213, 1992. (Epub ---)
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De Sutter, K, Feys, V, Van de Voorde, A, Fiers, W. Production of functionally active murine and murine::human chimeric F(ab')2 fragments in COS-1 cells Gene 113, 223-230, 1992. (Epub ---)
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De Sutter, K, Remaut, E, Fiers, W. Disulphide bridge formation in the periplasm of Escherichia coli: beta-lactamase::human IgG3 hinge fusions as a model system Mol Microbiol 6, 2201-2208, 1992. (Epub ---)
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Devos, K, Duerinck, F, Van Audenhove, K, Fiers, W. Cloning and expression of the canine interferon-gamma gene J Interferon Res 12, 95-102, 1992. (Epub ---)
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Feingold, KR, Doerrler, W, Dinarello, CA, Fiers, W, Grunfeld, C. Stimulation of lipolysis in cultured fat cells by tumor necrosis factor, interleukin-1, and the interferons is blocked by inhibition of prostaglandin synthesis Endocrinology 130, 10-16, 1992. (Epub ---)
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Fiers, W. De tumor-necrosefactor Natuur & Techniek 60, 664-675, 1992. (Epub ---)
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Fiers, W. Precursor structures and structure-function analysis of TNF and lymphotoxin In Tumor Necrosis Factors Structure, Function, and Mechanism of Action. (Aggarwal, BB, Vilcek, J, eds.), New York-Basel-Hong Kong, Marcel Dekker, pp. 79-92, 1992. (Epub ---)
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Fiers, W. Von der bakteriellen Infektion zur Krebstherapie Naturwissenschaftliche Rundschau 45, 426-428, 1992. (Epub ---)
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Fiers, W, Beyaert, R, Brouckaert, P, Decoster, E, De Valck, D, Everaerdt, B, Grooten, J, Lenaerts, A, Libert, C, Schulze-Osthoff, K, Takahashi, N, Tavernier, J, Van Bladel, S, Van Dorpe, C, Vanhaesebroeck, B, Van Ostade, X, Van Roy, F. Tumor necrosis factor: Mechanism of action at the molecular, cellular and in vivo level In Tumor Necrosis Factor: Structure-function Relationship and Clinical Application. (Osawa, T, Bonavida, B, eds.), Basel, Karger, pp. 66-73, 1992. (Epub ---)
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Fiers, W, Beyaert, R, Brouckaert, P, Decoster, E, De Valck, D, Everaerdt, B, Grooten, J, Lenaerts, A, Libert, C, Schulze-Osthoff, K, Takahashi, N, Van Bladel, S, Van Dorpe, C, Vanhaesebroeck, B, Van Ostade, X, Van Roy, F. Tumor necrosis factor: Mechanism of action and its potential for anticancer therapy In Molecular Aspects of Chemotherapy. , pp. 119-125, 1992. (Epub ---)
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Goldman, GH, Demolder, J, Dewaele, S, Herrera-Estrella, A, Geremia, RA, Van Montagu, M, Contreras, R. Molecular cloning of the imidazoleglycerolphosphate dehydratase gene of Trichoderma harzianum by genetic complementation in Saccharomyces cerevisiae using a direct expression vector Mol Gen Genet 234, 481-488, 1992. (Epub ---)
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Libert, C, Vink, A, Coulie, P, Brouckaert, P, Everaerdt, B, Van Snick, J, Fiers, W. Limited involvement of interleukin-6 in the pathogenesis of lethal septic shock as revealed by the effect of monoclonal antibodies against interleukin-6 or its receptor in various murine models Eur J Immunol 22, 2625-2630, 1992. (Epub ---)
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Mareel, M, Vleminckx, K, Gao, Y, Van Larebeke, N, Bracke, M, Van Roy, F. Modulation of invasion in vitro and in vivo In Metastasis: Basic Research and its Clinical Applications. (Rabes, H, Peters, PE, Munk, K, eds.), Contributions to Oncology, Freiburg, Karger, pp. 141-153, 1992. (Epub ---)
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Mareel, M, Vleminckx, K, Vermeulen, S, Bracke, M, Van Roy, F. E-cadherin expression: a counterbalance for cancer cell invasion Bull Cancer 79, 347-355, 1992. (Epub ---)
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Mareel, M, Vleminckx, K, Vermeulen, S, Gao, Y, Vakaet Jr., L, Bracke, M, Van Roy, F. Homotypic cell-cell adhesion molecules and tumor invasion Prog Histochem Cytochem 26, 95-106, 1992. (Epub ---)
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Oliver, SG, van der Aart, QJM, Agostoni-Carbone, ML, Aigle, M, Alberghina, L, Alexandraki, D, Antoine, G, Anwar, R, Ballesta, JPG, Benit, P, Berben, G, Bergantino, E, Biteau, N, Bolle, PA, Bolotin-Fukuhara, M, Brown, A, Brown, AJP, Buhler, JM, Carcano, C, et al.. The complete DNA sequence of yeast chromosome III Nature 357, 38-46, 1992. (Epub ---)
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Schulze-Osthoff, K, Bakker, AC, Vanhaesebroeck, B, Beyaert, R, Jacob, WA, Fiers, W. Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation J Biol Chem 267, 5317-5323, 1992. (Epub ---)
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Tavernier, J, Tuypens, T, Plaetinck, G, Verhee, A, Fiers, W, Devos, R. Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor a subunit Proc Natl Acad Sci USA 89, 7041-7045, 1992. (Epub ---)
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Tuypens, T, Plaetinck, G, Baker, E, Sutherland, G, Brusselle, G, Fiers, W, Devos, R, Tavernier, J. Organization and chromosomal localization of the human interleukin 5 receptor alpha-chain gene Eur Cytokine Netw 3, 451-459, 1992. (Epub ---)
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Unkles, SE, Campbell, EI, Punt, PJ, Hawker, KL, Contreras, R, Hawkins, AR, Van den Hondel, CA, Kinghorn, JR. The Aspergillus niger niaD gene encoding nitrate reductase: Upstream nucleotide and amino acid sequence comparisons Gene 111, 149-155, 1992. (Epub ---)
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Vandenabeele, P, Declercq, W, Vercammen, D, Van de Craen, M, Grooten, J, Loetscher, H, Brockhaus, M, Lesslauer, W, Fiers, W. Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma J Exp Med 176, 1015-1024, 1992. (Epub ---)
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Vandevoorde, V, Haegeman, G, Fiers, W. TNF-mediated IL6 gene expression and cytotoxicity are co-inducible in TNF-resistant L929 cells FEBS Lett 302, 235-238, 1992. (Epub ---)
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Vanhaesebroeck, B, Decoster, E, Van Ostade, X, Van Bladel, S, Lenaerts, A, Van Roy, F, Fiers, W. Expression of an exogenous tumor necrosis factor (TNF) gene in TNF-sensitive cell lines confers resistance to TNF-mediated cell lysis J Immunol 148, 2785-2794, 1992. (Epub ---)
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Van Lint, J, Agostinis, P, Vandevoorde, V, Haegeman, G, Fiers, W, Merlevede, W, Vandenheede, JR. Tumor necrosis factor stimulates multiple serine/threonine protein kinases in Swiss 3T3 and L929 cells. Implication of casein kinase-2 and extracellular signal-regulated kinases in the tumor necrosis factor signal transduction pathway J Biol Chem 267, 25916-25921, 1992. (Epub ---)
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Van Roy, F, Mareel, M. Tumour invasion: effects of cell adhesion and motility Trends Cell Biol 2, 163-169, 1992. (Epub ---)
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Van Roy, F, Vleminckx, K, Vakaet Jr., L, Berx, G, Fiers, W, Mareel, M. The invasion suppressor role of E-cadherin In Metastasis: Basic Research and its Clinical Applications. (Rabes, H, Peters, PE, Munk, K, eds.), Contributions to Oncology, Vol. 44, Basel, Karger, pp. 108-126, 1992. (Epub ---)
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Alegre, ML, Gastaldello, K, Abramowicz, D, Kinnaert, P, Vereerstraeten, P, De Pauw, L, Vandenabeele, P, Moser, M, Leo, O, Goldman, M. Evidence that pentoxifylline reduces anti-CD3 monoclonal antibody-induced cytokine release syndrome Transplantation 52, 674-679, 1991. (Epub ---)
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Alegre, M-L, Vandenabeele, P, Depierreux, M, Florquin, S, Deschodt-Lanckman, M, Flamand, V, Moser, M, Leo, O, Urbain, J, Fiers, W, Goldman, M. Cytokine release syndrome induced by the 145-2C11 anti-CD3 monoclonal antibody in mice: Prevention by high doses of methylprednisolone J Immunol 146, 1184-1191, 1991. (Epub ---)
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Beyaert, R, De Potter, C, Vanhaesebroeck, B, Van Roy, F, Fiers, W. Induction of inflammatory cell infiltration and necrosis in normal mouse skin by the combined treatment of tumor necrosis factor and lithium chloride Am J Pathol 138, 727-739, 1991. (Epub ---)
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Beyaert, R, Schulze-Osthoff, K, Van Roy, F, Fiers, W. Lithium chloride potentiates tumor necrosis factor-induced and interleukin 1-induced cytokine and cytokine receptor expression Cytokine 3, 284-291, 1991. (Epub ---)
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Contreras, R, Carrez, D, Kinghorn, JR, van den Hondel, CAMJJ, Fiers, W. Efficient KEX2-like processing of a glucoamylase-interleukin-6 fusion protein by Aspergillus nidulans and secretion of mature interleukin-6 Bio/Technology 9, 378-381, 1991. (Epub ---)
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Contreras, R, Demolder, J, Fiers, W. Cloning and expression of cytokine genes In Cytokines A Practical Approach. (Balkwill, FR, ed.), Oxford, IRL Press, pp. 1-16, 1991. (Epub ---)
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Coopman, P, Bracke, M, Lissitzky, J-C, De Bruyne, GK, Van Roy, FM, Foidart, J-M, Mareel, MM. Influence of basement membrane molecules on directional migration of human breast cell lines in vitro J Cell Sci 98, 395-401, 1991. (Epub ---)
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Coopman, P, Verhasselt, B, Bracke, M, De Bruyne, G, Castronovo, V, Sobel, M, Foidart, JM, Van Roy, F, Mareel, M. Arrest of MCF-7 cell migration by laminin in vitro: Possible mechanisms Clin Exp Metastas 9, 469-484, 1991. (Epub ---)
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Devos, R, Plaetinck, G, Van der Heyden, J, Cornelis, S, Vandekerckhove, J, Fiers, W, Tavernier, J. Molecular basis of a high affinity murine interleukin-5 receptor EMBO J 10, 2133-2137, 1991. (Epub ---)
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Devos, R, Vandekerckhove, J, Rolink, A, Plaetinck, G, Van der Heyden, J, Fiers, W, Tavernier, J. Amino acid sequence analysis of a mouse interleukin 5 receptor protein reveals homology with a mouse interleukin 3 receptor protein Eur J Immunol 21, 1315-1317, 1991. (Epub ---)
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Fiers, W. Molecular biology approaches to cancer and to cancer therapy In Primary Prevention and Cancer. (Eylenbosch, WJ, Kirsch-Volders, M, Deleener, A, Weyler, J, eds.), Recent Results in Cancer ResearchVol. 122, Berlin, Springer-Verlag, pp. 1-8, 1991. (Epub ---)
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Fiers, W. Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level FEBS Lett 285, 199-212, 1991. (Epub ---)
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