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Beyaert, R, Fiers, W.
Potentiation of tumour necrosis factor-mediated activities by lithium salts: A review
Lithium 3, 181-189, 1992. (Epub ---)

Beyaert, R, Schulze-Osthoff, K, Van Roy, F, Fiers, W.
Synergistic induction of interleukin-6 by tumor necrosis factor and lithium chloride in mice: Possible role in the triggering and exacerbation of psoriasis by lithium treatment
Eur J Immunol 22, 2181-2184, 1992. (Epub ---)

Brouckaert, P, Everaerdt, B, Fiers, W.
The glucocorticoid antagonist RU38486 mimics interleukin-1 in its sensitization to the lethal and interleukin-6-inducing properties of tumor necrosis factor
Eur J Immunol 22, 981-986, 1992. (Epub ---)

Brouckaert, PGG, Fiers, W, Lejeune, FJ.
Coley's vaccine and TNF therapy
Nature 358, 630, 1992. (Epub ---)

Brouckaert, P, Libert, C, Everaerdt, B, Fiers, W.
Selective species specificity of tumor necrosis factor for toxicity in the mouse
Lymphokine Cytokine Res 11, 193-196, 1992. (Epub ---)

Demolder, J, Fiers, W, Contreras, R.
Efficient synthesis of secreted murine interleukin-2 by Saccharomyces cerevisiae: Influence of 3'-untranslated regions and codon usage
Gene 111, 207-213, 1992. (Epub ---)

De Sutter, K, Feys, V, Van de Voorde, A, Fiers, W.
Production of functionally active murine and murine::human chimeric F(ab')2 fragments in COS-1 cells
Gene 113, 223-230, 1992. (Epub ---)

De Sutter, K, Remaut, E, Fiers, W.
Disulphide bridge formation in the periplasm of Escherichia coli: beta-lactamase::human IgG3 hinge fusions as a model system
Mol Microbiol 6, 2201-2208, 1992. (Epub ---)

Devos, K, Duerinck, F, Van Audenhove, K, Fiers, W.
Cloning and expression of the canine interferon-gamma gene
J Interferon Res 12, 95-102, 1992. (Epub ---)

Feingold, KR, Doerrler, W, Dinarello, CA, Fiers, W, Grunfeld, C.
Stimulation of lipolysis in cultured fat cells by tumor necrosis factor, interleukin-1, and the interferons is blocked by inhibition of prostaglandin synthesis
Endocrinology 130, 10-16, 1992. (Epub ---)

Fiers, W.
De tumor-necrosefactor
Natuur & Techniek 60, 664-675, 1992. (Epub ---)

Fiers, W.
Precursor structures and structure-function analysis of TNF and lymphotoxin
In Tumor Necrosis Factors Structure, Function, and Mechanism of Action. (Aggarwal, BB, Vilcek, J, eds.), New York-Basel-Hong Kong, Marcel Dekker, pp. 79-92, 1992. (Epub ---)

Fiers, W.
Von der bakteriellen Infektion zur Krebstherapie
Naturwissenschaftliche Rundschau 45, 426-428, 1992. (Epub ---)

Fiers, W, Beyaert, R, Brouckaert, P, Decoster, E, De Valck, D, Everaerdt, B, Grooten, J, Lenaerts, A, Libert, C, Schulze-Osthoff, K, Takahashi, N, Tavernier, J, Van Bladel, S, Van Dorpe, C, Vanhaesebroeck, B, Van Ostade, X, Van Roy, F.
Tumor necrosis factor: Mechanism of action at the molecular, cellular and in vivo level
In Tumor Necrosis Factor: Structure-function Relationship and Clinical Application. (Osawa, T, Bonavida, B, eds.), Basel, Karger, pp. 66-73, 1992. (Epub ---)

Fiers, W, Beyaert, R, Brouckaert, P, Decoster, E, De Valck, D, Everaerdt, B, Grooten, J, Lenaerts, A, Libert, C, Schulze-Osthoff, K, Takahashi, N, Van Bladel, S, Van Dorpe, C, Vanhaesebroeck, B, Van Ostade, X, Van Roy, F.
Tumor necrosis factor: Mechanism of action and its potential for anticancer therapy
In Molecular Aspects of Chemotherapy. , pp. 119-125, 1992. (Epub ---)

Goldman, GH, Demolder, J, Dewaele, S, Herrera-Estrella, A, Geremia, RA, Van Montagu, M, Contreras, R.
Molecular cloning of the imidazoleglycerolphosphate dehydratase gene of Trichoderma harzianum by genetic complementation in Saccharomyces cerevisiae using a direct expression vector
Mol Gen Genet 234, 481-488, 1992. (Epub ---)

Libert, C, Vink, A, Coulie, P, Brouckaert, P, Everaerdt, B, Van Snick, J, Fiers, W.
Limited involvement of interleukin-6 in the pathogenesis of lethal septic shock as revealed by the effect of monoclonal antibodies against interleukin-6 or its receptor in various murine models
Eur J Immunol 22, 2625-2630, 1992. (Epub ---)

Mareel, M, Vleminckx, K, Gao, Y, Van Larebeke, N, Bracke, M, Van Roy, F.
Modulation of invasion in vitro and in vivo
In Metastasis: Basic Research and its Clinical Applications. (Rabes, H, Peters, PE, Munk, K, eds.), Contributions to Oncology, Freiburg, Karger, pp. 141-153, 1992. (Epub ---)

Mareel, M, Vleminckx, K, Vermeulen, S, Bracke, M, Van Roy, F.
E-cadherin expression: a counterbalance for cancer cell invasion
Bull Cancer 79, 347-355, 1992. (Epub ---)

Mareel, M, Vleminckx, K, Vermeulen, S, Gao, Y, Vakaet Jr., L, Bracke, M, Van Roy, F.
Homotypic cell-cell adhesion molecules and tumor invasion
Prog Histochem Cytochem 26, 95-106, 1992. (Epub ---)

Oliver, SG, van der Aart, QJM, Agostoni-Carbone, ML, Aigle, M, Alberghina, L, Alexandraki, D, Antoine, G, Anwar, R, Ballesta, JPG, Benit, P, Berben, G, Bergantino, E, Biteau, N, Bolle, PA, Bolotin-Fukuhara, M, Brown, A, Brown, AJP, Buhler, JM, Carcano, C, et al..
The complete DNA sequence of yeast chromosome III
Nature 357, 38-46, 1992. (Epub ---)

Schulze-Osthoff, K, Bakker, AC, Vanhaesebroeck, B, Beyaert, R, Jacob, WA, Fiers, W.
Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation
J Biol Chem 267, 5317-5323, 1992. (Epub ---)

Tavernier, J, Tuypens, T, Plaetinck, G, Verhee, A, Fiers, W, Devos, R.
Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor a subunit
Proc Natl Acad Sci USA 89, 7041-7045, 1992. (Epub ---)

Tuypens, T, Plaetinck, G, Baker, E, Sutherland, G, Brusselle, G, Fiers, W, Devos, R, Tavernier, J.
Organization and chromosomal localization of the human interleukin 5 receptor alpha-chain gene
Eur Cytokine Netw 3, 451-459, 1992. (Epub ---)

Unkles, SE, Campbell, EI, Punt, PJ, Hawker, KL, Contreras, R, Hawkins, AR, Van den Hondel, CA, Kinghorn, JR.
The Aspergillus niger niaD gene encoding nitrate reductase: Upstream nucleotide and amino acid sequence comparisons
Gene 111, 149-155, 1992. (Epub ---)

Vandenabeele, P, Declercq, W, Vercammen, D, Van de Craen, M, Grooten, J, Loetscher, H, Brockhaus, M, Lesslauer, W, Fiers, W.
Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma
J Exp Med 176, 1015-1024, 1992. (Epub ---)

Vandevoorde, V, Haegeman, G, Fiers, W.
TNF-mediated IL6 gene expression and cytotoxicity are co-inducible in TNF-resistant L929 cells
FEBS Lett 302, 235-238, 1992. (Epub ---)

Vanhaesebroeck, B, Decoster, E, Van Ostade, X, Van Bladel, S, Lenaerts, A, Van Roy, F, Fiers, W.
Expression of an exogenous tumor necrosis factor (TNF) gene in TNF-sensitive cell lines confers resistance to TNF-mediated cell lysis
J Immunol 148, 2785-2794, 1992. (Epub ---)

Van Lint, J, Agostinis, P, Vandevoorde, V, Haegeman, G, Fiers, W, Merlevede, W, Vandenheede, JR.
Tumor necrosis factor stimulates multiple serine/threonine protein kinases in Swiss 3T3 and L929 cells. Implication of casein kinase-2 and extracellular signal-regulated kinases in the tumor necrosis factor signal transduction pathway
J Biol Chem 267, 25916-25921, 1992. (Epub ---)

Van Roy, F, Mareel, M.
Tumour invasion: effects of cell adhesion and motility
Trends Cell Biol 2, 163-169, 1992. (Epub ---)

Van Roy, F, Vleminckx, K, Vakaet Jr., L, Berx, G, Fiers, W, Mareel, M.
The invasion suppressor role of E-cadherin
In Metastasis: Basic Research and its Clinical Applications. (Rabes, H, Peters, PE, Munk, K, eds.), Contributions to Oncology, Vol. 44, Basel, Karger, pp. 108-126, 1992. (Epub ---)

Alegre, ML, Gastaldello, K, Abramowicz, D, Kinnaert, P, Vereerstraeten, P, De Pauw, L, Vandenabeele, P, Moser, M, Leo, O, Goldman, M.
Evidence that pentoxifylline reduces anti-CD3 monoclonal antibody-induced cytokine release syndrome
Transplantation 52, 674-679, 1991. (Epub ---)

Alegre, M-L, Vandenabeele, P, Depierreux, M, Florquin, S, Deschodt-Lanckman, M, Flamand, V, Moser, M, Leo, O, Urbain, J, Fiers, W, Goldman, M.
Cytokine release syndrome induced by the 145-2C11 anti-CD3 monoclonal antibody in mice: Prevention by high doses of methylprednisolone
J Immunol 146, 1184-1191, 1991. (Epub ---)

Beyaert, R, De Potter, C, Vanhaesebroeck, B, Van Roy, F, Fiers, W.
Induction of inflammatory cell infiltration and necrosis in normal mouse skin by the combined treatment of tumor necrosis factor and lithium chloride
Am J Pathol 138, 727-739, 1991. (Epub ---)

Beyaert, R, Schulze-Osthoff, K, Van Roy, F, Fiers, W.
Lithium chloride potentiates tumor necrosis factor-induced and interleukin 1-induced cytokine and cytokine receptor expression
Cytokine 3, 284-291, 1991. (Epub ---)

Contreras, R, Carrez, D, Kinghorn, JR, van den Hondel, CAMJJ, Fiers, W.
Efficient KEX2-like processing of a glucoamylase-interleukin-6 fusion protein by Aspergillus nidulans and secretion of mature interleukin-6
Bio/Technology 9, 378-381, 1991. (Epub ---)

Contreras, R, Demolder, J, Fiers, W.
Cloning and expression of cytokine genes
In Cytokines A Practical Approach. (Balkwill, FR, ed.), Oxford, IRL Press, pp. 1-16, 1991. (Epub ---)

Coopman, P, Bracke, M, Lissitzky, J-C, De Bruyne, GK, Van Roy, FM, Foidart, J-M, Mareel, MM.
Influence of basement membrane molecules on directional migration of human breast cell lines in vitro
J Cell Sci 98, 395-401, 1991. (Epub ---)

Coopman, P, Verhasselt, B, Bracke, M, De Bruyne, G, Castronovo, V, Sobel, M, Foidart, JM, Van Roy, F, Mareel, M.
Arrest of MCF-7 cell migration by laminin in vitro: Possible mechanisms
Clin Exp Metastas 9, 469-484, 1991. (Epub ---)

Devos, R, Plaetinck, G, Van der Heyden, J, Cornelis, S, Vandekerckhove, J, Fiers, W, Tavernier, J.
Molecular basis of a high affinity murine interleukin-5 receptor
EMBO J 10, 2133-2137, 1991. (Epub ---)

Devos, R, Vandekerckhove, J, Rolink, A, Plaetinck, G, Van der Heyden, J, Fiers, W, Tavernier, J.
Amino acid sequence analysis of a mouse interleukin 5 receptor protein reveals homology with a mouse interleukin 3 receptor protein
Eur J Immunol 21, 1315-1317, 1991. (Epub ---)

Fiers, W.
Molecular biology approaches to cancer and to cancer therapy
In Primary Prevention and Cancer. (Eylenbosch, WJ, Kirsch-Volders, M, Deleener, A, Weyler, J, eds.), Recent Results in Cancer ResearchVol. 122, Berlin, Springer-Verlag, pp. 1-8, 1991. (Epub ---)

Fiers, W.
Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level
FEBS Lett 285, 199-212, 1991. (Epub ---)

Franco, L, Jiménez, A, Demolder, J, Molemans, F, Fiers, W, Contreras, R.
The nucleotide sequence of a third cyclophilin-homologous gene from Saccharomyces cerevisiae
Yeast 7, 971-979, 1991. (Epub ---)

Grunfeld, C, Soued, M, Adi, S, Moser, AH, Fiers, W, Dinarello, CA, Feingold, KR.
Interleukin 4 inhibits stimulation of hepatic lipogenesis by tumor necrosis factor, interleukin 1, and interleukin 6 but not by interferon-alpha
Cancer Res 51, 2803-2807, 1991. (Epub ---)

Guisez, Y, Tison, B, Vandekerckhove, J, Demolder, J, Bauw, G, Haegeman, G, Fiers, W, Contreras, R.
Production and purification of recombinant human interleukin-6 secreted by the yeast Saccharomyces cerevisiae
Eur J Biochem 198, 217-222, 1991. (Epub ---)

Haegeman, G, Vandevoorde, V, Fiers, W.
Tumor necrosis factor-induced gene expression and cytotoxicity share a signal transduction pathway
In Cellular Regulation by Protein Phosphorylation. (Heilmeyer Jr., LMG, ed.), NATO ASI Series, Vol. H 56, Berlin, Springer,, pp. 471-475, 1991. (Epub ---)

Kordula, T, Rokita, H, Koj, A, Fiers, W, Gauldie, J, Baumann, H.
Effects of interleukin-6 and leukemia inhibitory factor on the acute phase response and DNA synthesis in cultured rat hepatocytes
Lymphokine Cytokine Res 10, 23-26, 1991. (Epub ---)

Langeler, EG, Fiers, W, van Hinsbergh, VWM.
Effects of tumor necrosis factor on prostacyclin production and the barrier function of human endothelial cell monolayers
Arteriosclerosis Thrombosis 11, 872-881, 1991. (Epub ---)

Libert, C, Van Bladel, S, Brouckaert, P, Fiers, W.
The influence of modulating substances on tumor necrosis factor and interleukin-6 levels after injection of murine tumor necrosis factor or lipopolysaccharide in mice
J Immunother 10, 227-235, 1991. (Epub ---)

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