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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Mareel, M, Vleminckx, K, Gao, Y, Van Larebeke, N, Bracke, M, Van Roy, F. Modulation of invasion in vitro and in vivo In Metastasis: Basic Research and its Clinical Applications. (Rabes, H, Peters, PE, Munk, K, eds.), Contributions to Oncology, Freiburg, Karger, pp. 141-153, 1992. (Epub ---) 
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Mareel, M, Vleminckx, K, Vermeulen, S, Bracke, M, Van Roy, F. E-cadherin expression: a counterbalance for cancer cell invasion Bull Cancer 79, 347-355, 1992. (Epub ---)
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Mareel, M, Vleminckx, K, Vermeulen, S, Gao, Y, Vakaet Jr., L, Bracke, M, Van Roy, F. Homotypic cell-cell adhesion molecules and tumor invasion Prog Histochem Cytochem 26, 95-106, 1992. (Epub ---)
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Oliver, SG, van der Aart, QJM, Agostoni-Carbone, ML, Aigle, M, Alberghina, L, Alexandraki, D, Antoine, G, Anwar, R, Ballesta, JPG, Benit, P, Berben, G, Bergantino, E, Biteau, N, Bolle, PA, Bolotin-Fukuhara, M, Brown, A, Brown, AJP, Buhler, JM, Carcano, C, et al.. The complete DNA sequence of yeast chromosome III Nature 357, 38-46, 1992. (Epub ---) 
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Schulze-Osthoff, K, Bakker, AC, Vanhaesebroeck, B, Beyaert, R, Jacob, WA, Fiers, W. Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. Evidence for the involvement of mitochondrial radical generation J Biol Chem 267, 5317-5323, 1992. (Epub ---)
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Tavernier, J, Tuypens, T, Plaetinck, G, Verhee, A, Fiers, W, Devos, R. Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor a subunit Proc Natl Acad Sci USA 89, 7041-7045, 1992. (Epub ---)
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Tuypens, T, Plaetinck, G, Baker, E, Sutherland, G, Brusselle, G, Fiers, W, Devos, R, Tavernier, J. Organization and chromosomal localization of the human interleukin 5 receptor alpha-chain gene Eur Cytokine Netw 3, 451-459, 1992. (Epub ---)
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Unkles, SE, Campbell, EI, Punt, PJ, Hawker, KL, Contreras, R, Hawkins, AR, Van den Hondel, CA, Kinghorn, JR. The Aspergillus niger niaD gene encoding nitrate reductase: Upstream nucleotide and amino acid sequence comparisons Gene 111, 149-155, 1992. (Epub ---)
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Vandenabeele, P, Declercq, W, Vercammen, D, Van de Craen, M, Grooten, J, Loetscher, H, Brockhaus, M, Lesslauer, W, Fiers, W. Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma J Exp Med 176, 1015-1024, 1992. (Epub ---)
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Vandevoorde, V, Haegeman, G, Fiers, W. TNF-mediated IL6 gene expression and cytotoxicity are co-inducible in TNF-resistant L929 cells FEBS Lett 302, 235-238, 1992. (Epub ---)
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Vanhaesebroeck, B, Decoster, E, Van Ostade, X, Van Bladel, S, Lenaerts, A, Van Roy, F, Fiers, W. Expression of an exogenous tumor necrosis factor (TNF) gene in TNF-sensitive cell lines confers resistance to TNF-mediated cell lysis J Immunol 148, 2785-2794, 1992. (Epub ---)
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Van Lint, J, Agostinis, P, Vandevoorde, V, Haegeman, G, Fiers, W, Merlevede, W, Vandenheede, JR. Tumor necrosis factor stimulates multiple serine/threonine protein kinases in Swiss 3T3 and L929 cells. Implication of casein kinase-2 and extracellular signal-regulated kinases in the tumor necrosis factor signal transduction pathway J Biol Chem 267, 25916-25921, 1992. (Epub ---)
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Van Roy, F, Mareel, M. Tumour invasion: effects of cell adhesion and motility Trends Cell Biol 2, 163-169, 1992. (Epub ---)
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Van Roy, F, Vleminckx, K, Vakaet Jr., L, Berx, G, Fiers, W, Mareel, M. The invasion suppressor role of E-cadherin In Metastasis: Basic Research and its Clinical Applications. (Rabes, H, Peters, PE, Munk, K, eds.), Contributions to Oncology, Vol. 44, Basel, Karger, pp. 108-126, 1992. (Epub ---)
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Alegre, ML, Gastaldello, K, Abramowicz, D, Kinnaert, P, Vereerstraeten, P, De Pauw, L, Vandenabeele, P, Moser, M, Leo, O, Goldman, M. Evidence that pentoxifylline reduces anti-CD3 monoclonal antibody-induced cytokine release syndrome Transplantation 52, 674-679, 1991. (Epub ---)
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Alegre, M-L, Vandenabeele, P, Depierreux, M, Florquin, S, Deschodt-Lanckman, M, Flamand, V, Moser, M, Leo, O, Urbain, J, Fiers, W, Goldman, M. Cytokine release syndrome induced by the 145-2C11 anti-CD3 monoclonal antibody in mice: Prevention by high doses of methylprednisolone J Immunol 146, 1184-1191, 1991. (Epub ---)
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Beyaert, R, De Potter, C, Vanhaesebroeck, B, Van Roy, F, Fiers, W. Induction of inflammatory cell infiltration and necrosis in normal mouse skin by the combined treatment of tumor necrosis factor and lithium chloride Am J Pathol 138, 727-739, 1991. (Epub ---)
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Beyaert, R, Schulze-Osthoff, K, Van Roy, F, Fiers, W. Lithium chloride potentiates tumor necrosis factor-induced and interleukin 1-induced cytokine and cytokine receptor expression Cytokine 3, 284-291, 1991. (Epub ---)
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Contreras, R, Carrez, D, Kinghorn, JR, van den Hondel, CAMJJ, Fiers, W. Efficient KEX2-like processing of a glucoamylase-interleukin-6 fusion protein by Aspergillus nidulans and secretion of mature interleukin-6 Bio/Technology 9, 378-381, 1991. (Epub ---)
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Contreras, R, Demolder, J, Fiers, W. Cloning and expression of cytokine genes In Cytokines A Practical Approach. (Balkwill, FR, ed.), Oxford, IRL Press, pp. 1-16, 1991. (Epub ---)
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Coopman, P, Bracke, M, Lissitzky, J-C, De Bruyne, GK, Van Roy, FM, Foidart, J-M, Mareel, MM. Influence of basement membrane molecules on directional migration of human breast cell lines in vitro J Cell Sci 98, 395-401, 1991. (Epub ---)
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Coopman, P, Verhasselt, B, Bracke, M, De Bruyne, G, Castronovo, V, Sobel, M, Foidart, JM, Van Roy, F, Mareel, M. Arrest of MCF-7 cell migration by laminin in vitro: Possible mechanisms Clin Exp Metastas 9, 469-484, 1991. (Epub ---)
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Devos, R, Plaetinck, G, Van der Heyden, J, Cornelis, S, Vandekerckhove, J, Fiers, W, Tavernier, J. Molecular basis of a high affinity murine interleukin-5 receptor EMBO J 10, 2133-2137, 1991. (Epub ---)
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Devos, R, Vandekerckhove, J, Rolink, A, Plaetinck, G, Van der Heyden, J, Fiers, W, Tavernier, J. Amino acid sequence analysis of a mouse interleukin 5 receptor protein reveals homology with a mouse interleukin 3 receptor protein Eur J Immunol 21, 1315-1317, 1991. (Epub ---)
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Fiers, W. Molecular biology approaches to cancer and to cancer therapy In Primary Prevention and Cancer. (Eylenbosch, WJ, Kirsch-Volders, M, Deleener, A, Weyler, J, eds.), Recent Results in Cancer ResearchVol. 122, Berlin, Springer-Verlag, pp. 1-8, 1991. (Epub ---)
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Fiers, W. Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level FEBS Lett 285, 199-212, 1991. (Epub ---)
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Franco, L, Jiménez, A, Demolder, J, Molemans, F, Fiers, W, Contreras, R. The nucleotide sequence of a third cyclophilin-homologous gene from Saccharomyces cerevisiae Yeast 7, 971-979, 1991. (Epub ---)
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Grunfeld, C, Soued, M, Adi, S, Moser, AH, Fiers, W, Dinarello, CA, Feingold, KR. Interleukin 4 inhibits stimulation of hepatic lipogenesis by tumor necrosis factor, interleukin 1, and interleukin 6 but not by interferon-alpha Cancer Res 51, 2803-2807, 1991. (Epub ---)
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Guisez, Y, Tison, B, Vandekerckhove, J, Demolder, J, Bauw, G, Haegeman, G, Fiers, W, Contreras, R. Production and purification of recombinant human interleukin-6 secreted by the yeast Saccharomyces cerevisiae Eur J Biochem 198, 217-222, 1991. (Epub ---)
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Haegeman, G, Vandevoorde, V, Fiers, W. Tumor necrosis factor-induced gene expression and cytotoxicity share a signal transduction pathway In Cellular Regulation by Protein Phosphorylation. (Heilmeyer Jr., LMG, ed.), NATO ASI Series, Vol. H 56, Berlin, Springer,, pp. 471-475, 1991. (Epub ---)
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Kordula, T, Rokita, H, Koj, A, Fiers, W, Gauldie, J, Baumann, H. Effects of interleukin-6 and leukemia inhibitory factor on the acute phase response and DNA synthesis in cultured rat hepatocytes Lymphokine Cytokine Res 10, 23-26, 1991. (Epub ---)
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Langeler, EG, Fiers, W, van Hinsbergh, VWM. Effects of tumor necrosis factor on prostacyclin production and the barrier function of human endothelial cell monolayers Arteriosclerosis Thrombosis 11, 872-881, 1991. (Epub ---)
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Libert, C, Van Bladel, S, Brouckaert, P, Fiers, W. The influence of modulating substances on tumor necrosis factor and interleukin-6 levels after injection of murine tumor necrosis factor or lipopolysaccharide in mice J Immunother 10, 227-235, 1991. (Epub ---)
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Libert, C, Van Bladel, S, Brouckaert, P, Shaw, A, Fiers, W. Involvement of the liver, but not of IL-6, in IL-1-induced desensitization to the lethal effects of tumor necrosis factor J Immunol 146, 2625-2632, 1991. (Epub ---)
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Mareel, M, Bracke, M, Gao, Y, Van Roy, F. Normal and chimeric avian embryo ecosystems of invasion Eur Arch Biol 102, 185-188, 1991. (Epub ---)
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Mareel, MM, Behrens, J, Birchmeier, W, De Bruyne, GK, Vleminckx, K, Hoogewijs, A, Fiers, WC, Van Roy, FM. Down-regulation of E-cadherin expression in Madin Darby canine kidney (MDCK) cells inside tumors of nude mice Int J Cancer 47, 922-928, 1991. (Epub ---)
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Mareel, MM, De Baetselier, P, Van Roy, FM. Mechanisms of Invasion and Metastasis Boca Raton, UniScience Books , 651 pages, 1991. (Epub ---)
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Messiaen, L, Qian, S, De Bruyne, G, Boghaert, E, Moens, T, Rabaey, M, Van Roy, F, Mareel, M. Spontaneous acquisition of tumorigenicity and invasiveness by mouse lens explant cells during culture in vitro In Vitro Cell Devel Biol 27A, 369-380, 1991. (Epub ---)
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Nortier, J, Vandenabeele, P, Noel, E, Bosseloir, Y, Goldman, M, Deschodt-Lanckman, M. Enzymatic degradation of tumor necrosis factor by activated human neutrophils: Role of elastase Life Sci 49, 1879-1886, 1991. (Epub ---)
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Robaye, B, Mosselmans, R, Fiers, W, Dumont, JE, Galand, P. Tumor necrosis factor induces apoptosis (programmed cell death) in normal endothelial cells in vitro Am J Pathol 138, 447-453, 1991. (Epub ---)
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Schulze-Osthoff, K, Fiers, W. Die Rolle des Tumor-Nekrose-Faktors im septischen Schock Die Gelben Hefte 31, 61-67, 1991. (Epub ---)
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Schulze-Osthoff, K, Fiers, W. Oxygen radicals as second messengers Trends Cell Biol 1, 150, 1991. (Epub ---)
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Suffys, P, Beyaert, R, De Valck, D, Vanhaesebroeck, B, Van Roy, F, Fiers, W. Tumour-necrosis-factor-mediated cytotoxicity is correlated with phospholipase-A2 activity, but not with arachidonic acid release per se Eur J Biochem 195, 465-475, 1991. (Epub ---)
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Takahashi, N, Brouckaert, P, Fiers, W. Induction of tolerance allows separation of lethal and antitumor activities of tumor necrosis factor in mice Cancer Res 51, 2366-2372, 1991. (Epub ---)
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Tavernier, J, Devos, R, Cornelis, S, Tuypens, T, Van der Heyden, J, Fiers, W, Plaetinck, G. A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific a chain and a b chain shared with the receptor for GM-CSF Cell 66, 1175-1184, 1991. (Epub ---)
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Vakaet Jr., L, Vleminckx, K, Van Roy, F, Mareel, M. Numerical evaluation of the invasion of closely related cell lines into collagen type I gels Invasion Metastasis 11, 469-484, 1991. (Epub ---)
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Van Bladel, S, Libert, C, Fiers, W. Interleukin-6 enhances the expression of tumor necrosis factor receptors on hepatoma cells and hepatocytes Cytokine 3, 149-154, 1991. (Epub ---)
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Vandenabeele, P, Fiers, W. Is amyloidogenesis during Alzheimer's disease due to an IL-1/IL-6-mediated 'acute phase response' in the brain? Immunol Today 12, 217-219, 1991. (Epub ---)
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Van der Heyden, J, Devos, R, Plaetinck, G, Faché, I, Fiers, W, Tavernier, J. Characterization of the murine IL-5 receptor complex with the use of a panel of monoclonal antibodies. Relationship to the murine IL-3 receptor J Immunol 147, 3413-3418, 1991. (Epub ---)
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Vandevoorde, V, Haegeman, G, Fiers, W. Tumor necrosis factor-induced interleukin-6 expression and cytotoxicity follow a common signal transduction pathway in L929 cells Biochem Biophys Res Commun 178, 993-1001, 1991. (Epub ---)
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