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Selected IRC publications
The IRC publications that match your query are listed below.
For copyright reasons, PDF-versions of our publications are available on the intranet only (login required 
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Baraliakos, X, Braun, J, Deodhar, A, Poddubnyy, D, Kivitz, A, Tahir, H, Van den Bosch, F, Delicha, EM, Talloczy, Z, Fierlinger, A. Long-term efficacy and safety of secukinumab 150 mg in ankylosing spondylitis: 5-year results from the phase III MEASURE 1 extension study RMD Open 5, e001005, 2019. (Epub 2019 Sep 3) 
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Beltran, S, Nassif, M, Vicencio, E, Arcos, J, Labrador, L, Cortes, BI, Cortez, C, Bergmann, CA, Espinoza, S, Hernandez, MF, Matamala, JM, Bargsted, L, Matus, S, Rojas-Rivera, D, Bertrand, MJM, Medinas, DB, Hetz, C, Manque, PA, Woehlbier, U. Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis Mol Neurodegener 14, 14, 2019. (Epub 2019 Mar 27)
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Beyens, A, Van Meensel, K, Pottie, L, De Rycke, R, De Bruyne, M, Baeke, F, Hoebeke, P, Plasschaert, F, Loeys, B, De Schepper, S, Symoens, S, Callewaert, B. Defining the Clinical, Molecular and Ultrastructural Characteristics in Occipital Horn Syndrome: Two New Cases and Review of the Literature Genes (Basel) 10, 528, 2019. (Epub 2019 Jul 12)
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Bibli, SI, Papapetropoulos, A, Iliodromitis, EK, Daiber, A, Randriamboavonjy, V, Steven, S, Brouckaert, P, Chatzianastasiou, A, Kypreos, KE, Hausenloy, DJ, Fleming, I, Andreadou, I. Nitroglycerin limits infarct size through S-nitrosation of Cyclophilin D: A novel mechanism for an old drug Cardiovasc Res 115, 625-636, 2019. (Epub 2018 Aug 27)
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Bieniasz-Krzywiec, P, Martin-Perez, R, Ehling, M, Garcia-Caballero, M, Pinioti, S, Pretto, S, Kroes, R, Aldeni, C, Di Matteo, M, Prenen, H, Tribulatti, MV, Campetella, O, Smeets, A, Noel, A, Floris, G, Van Ginderachter, JA, Mazzone, M. Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer Cell Metab 30, 917-936, 2019. (Epub 2019 Aug 19)
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Boeltz, S, Amini, P, Anders, HJ, Andrade, F, Bilyy, R, Chatfield, S, Cichon, I, Clancy, DM, Desai, J, et al., Maueroder, C, et al. , Vanden Berghe, T, Vandenabeele, P, Hahn, J, Hidalgo, A, Hoffmann, MH, Kaplan, MJ, Knight, JS, Kolaczkowska, E, Kubes, P, et al.. To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps Cell Death Differ 26, 395-408, 2019. (Epub 2019 Jan 8)
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Bolli, E, D'Huyvetter, M, Murgaski, A, Berus, D, Stange, G, Clappaert, EJ, Arnouk, S, Pombo Antunes, AR, Krasniqi, A, Lahoutte, T, Goncalves, A, Vuylsteke, M, Raes, G, Devoogdt, N, Movahedi, K, Van Ginderachter, JA. Stromal-targeting radioimmunotherapy mitigates the progression of therapy-resistant tumors J Control Release 314, 1-11, 2019. (Epub 2019 Oct 15)
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Bonnardel, J, T'Jonck, W, Gaublomme, D, Browaeys, R, Scott, CL, Martens, L, Vanneste, B, De Prijck, S, Nedospasov, SA, Kremer, A, Van Hamme, E, Borghgraef, P, Toussaint, W, De Bleser, P, Mannaerts, I, Beschin, A, van Grunsven, LA, Lambrecht, BN, Taghon, T, et al.. Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche Immunity 51, 638-654, 2019. (Epub 2019 Sep 24)
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Bougarne, N, Mylka, V, Ratman, D, Beck, IM, Thommis, J, De Cauwer, L, Tavernier, J, Staels, B, Libert, C, De Bosscher, K. Mechanisms Underlying the Functional Cooperation Between PPARalpha and GRalpha to Attenuate Inflammatory Responses Front Immunol 10, 1769, 2019. (Epub 2019 Aug 9)
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Braun, J, Haibel, H, de Hooge, M, Landewe, R, Rudwaleit, M, Fox, T, Readie, A, Richards, HB, Porter, B, Martin, R, Poddubnyy, D, Sieper, J, van der Heijde, D. Spinal radiographic progression over 2 years in ankylosing spondylitis patients treated with secukinumab: a historical cohort comparison Arthritis Res Ther 21, 142, 2019. (Epub 2019 Jun 7)
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Broos, K, Lecocq, Q, Keersmaecker, B, Raes, G, Corthals, J, Lion, E, Thielemans, K, Devoogdt, N, Keyaerts, M, Breckpot, K. Single Domain Antibody-Mediated Blockade of Programmed Death-Ligand 1 on Dendritic Cells Enhances CD8 T-cell Activation and Cytokine Production Vaccines (Basel) 7, 85, 2019. (Epub 2019 Aug 7)
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Broos, K, Lecocq, Q, Xavier, C, Bridoux, J, Nguyen, TT, Corthals, J, Schoonooghe, S, Lion, E, Raes, G, Keyaerts, M, Devoogdt, N, Breckpot, K. Evaluating a Single Domain Antibody Targeting Human PD-L1 as a Nuclear Imaging and Therapeutic Agent Cancers (Basel) 11, 6, 2019. (Epub 2019 Jun 21)
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Bruger, AM, Dorhoi, A, Esendagli, G, Barczyk-Kahlert, K, van der Bruggen, P, Lipoldova, M, Perecko, T, Santibanez, J, Saraiva, M, Van Ginderachter, JA, Brandau, S. How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions Cancer Immunol Immunother 68, 631-644, 2019. (Epub 2018 May 21)
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Cambre, I, Gaublomme, D, Schryvers, N, Lambrecht, S, Lories, R, Venken, K, Elewaut, D. Running promotes chronicity of arthritis by local modulation of complement activators and impairing T regulatory feedback loops Ann Rheum Dis 78, 787-795, 2019. (Epub 2019 Mar 30)
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Chuang, YT, Leung, K, Chang, YJ, DeKruyff, RH, Savag, PB, Cruse, R, Benoit, C, Elewaut, D, Baumgarth, N, Umetsu, DT. A Natural Killer T cell subset that protects against airway hyperreactivity J Allergy Clin Immunol 143, 565-576, 2019. (Epub 2018 May 28)
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Claudepierre, P, Van den Bosch, F, Sarzi-Puttini, P, Vastesaeger, N, Govoni, M, Kachroo, S. Treatment with golimumab or infliximab reduces health resource utilization and increases work productivity in patients with ankylosing spondylitis in the QUO-VADIS study, a large, prospective real-life cohort Int J Rheum Dis 22, 995-1001, 2019. (Epub 2019 Apr 15)
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Cochet, F, Facchini, FA, Zaffaroni, L, Billod, JM, Coelho, H, Holgado, A, Braun, H, Beyaert, R, Jerala, R, Jimenez-Barbero, J, Martin-Santamaria, S, Peri, F. Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties Sci Rep 9, 919, 2019. (Epub 2019 Jan 29)
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Coenen-Stass, AML, Pauwels, MJ, Hanson, B, Martin Perez, C, Conceicao, M, Wood, MJA, Mager, I, Roberts, TC. Extracellular microRNAs exhibit sequence-dependent stability and cellular release kinetics RNA Biol 16, 696-706, 2019. (Epub 2019 Mar 5)
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Corneillie, S, De Storme, N, Van Acker, R, Fangel, JU, De Bruyne, M, De Rycke, RM, Geelen, DNV, Willats, WGT, Vanholme, B, Boerjan, WA. Polyploidy affects plant growth and alters cell wall composition Plant Physiol 179, 74-87, 2019. (Epub 2018 Oct 9)
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Cossarizza, A, Chang, HD, Radbruch, A, Acs, A, Adam, D, Adam-Klages, S, Agace, WW, Aghaeepour, N, Akdis, M, Allez, M, Almeida, LN, Alvisi, G, Anderson, G, Andra, I, Annunziato, F, Anselmo, A, Bacher, P, Baldari, CT, Bari, S, et al.. Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) Eur J Immunol 49, 1457-1973, 2019. (Epub 2019 Oct)
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Czechowska, K, Lannigan, J, Wang, L, Arcidiacono, J, Ashhurst, TM, Barnard, RM, Bauer, S, Bispo, C, Bonilla, DL, Brinkman, RR, Cabanski, M, Chang, HD, Chakrabarti, L, Chojnowski, G, Cotleur, B, Degheidy, H, Dela Cruz, GV, et al., Van Isterdael, G, et al.. Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2018 Conference Workshops Cytometry A 95, 598-644, 2019. (Epub 2019 Jun 17)
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Das, T, Bergen, IM, Koudstaal, T, van Hulst, JAC, van Loo, G, Boonstra, A, Vanwolleghem, T, Leung, PSC, Gershwin, ME, Hendriks, RW, Kool, M. DNGR1-mediated deletion of A20/Tnfaip3 in dendritic cells alters T and B-cell homeostasis and promotes autoimmune liver pathology J Autoimmun 102, 167-178, 2019. (Epub 2019 May 28)
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Debeuf, N, Zhakupova, A, Steiner, R, Van Gassen, S, Deswarte, K, Fayazpour, F, Van Moorleghem, J, Vergote, K, Pavie, B, Lemeire, K, Hammad, H, Hornemann, T, Janssens, S, Lambrecht, BN. The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice J Allergy Clin Immunol 144, 1648-1659, 2019. (Epub 2019 Jul 20)
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Decaestecker, W, Andrade Buono, R, Pfeiffer, M, Vangheluwe, N, Jourquin, J, Karimi, M, van Isterdael, G, Beeckman, T, Nowack, MK, Jacobs, TB. CRISPR-TSKO: A Technique for Efficient Mutagenesis in Specific Cell Types, Tissues, or Organs in Arabidopsis Plant Cell 31, 2868-2887, 2019. (Epub 2019 Sep 27)
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Deckers, J, Lambrecht, BN, Hammad, H. How a farming environment protects from atopy Curr Opin Immunol 60, 163-169, 2019. (Epub 2019 Sep 6)
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De Coninck, S, Berx, G, Taghon, T, Van Vlierberghe, P, Goossens, S. ZEB2 in T-cells and T-ALL Adv Biol Regul 74, 100639, 2019. (Epub 2019 Jul 27)
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De Francesco, D, Wit, FW, Burkle, A, Oehlke, S, Kootstra, NA, Winston, A, Franceschi, C, Garagnani, P, Pirazzini, C, Libert, C, Grune, T, Weber, D, Jansen, E, Sabin, CA, Reiss, P, The Co-morBidity in Relation to, AC. Do people living with HIV experience greater age advancement than their HIV-negative counterparts? AIDS 33, 259–268, 2019. (Epub 2018 Oct 15)
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de Hooge, M, van Gaalen, FA, Renson, T, De Craemer, AS, van de Sande, MG, Ramonda, R, Fagerli, KM, Jacobsson, LTH, van der Heijde, D, Elewaut, D, Van den Bosch, F. Low specificity but high sensitivity of inflammatory back pain criteria in rheumatology settings in Europe: confirmation of findings from a German cohort study Ann Rheum Dis 78, 1605-1606, 2019. (Epub 2019 Jul 13)
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Dejonghe, W, Sharma, I, Denoo, B, De Munck, S, Lu, Q, Mishev, K, Bulut, H, Mylle, E, De Rycke, R, Vasileva, M, Savatin, DV, Nerinckx, W, Staes, A, Drozdzecki, A, Audenaert, D, Yperman, K, Madder, A, Friml, J, Van Damme, D, et al.. Disruption of endocytosis through chemical inhibition of clathrin heavy chain function Nat Chem Biol 15, 641–649, 2019. (Epub 2019 Apr 22)
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Delvaeye, T, De Smet, MAJ, Verwaerde, S, Decrock, E, Czekaj, A, Vandenbroucke, RE, Lemeire, K, Goncalves, A, Declercq, W, Vandenabeele, P, Krysko, DV, Leybaert, L. Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock Sci Rep 9, 16623, 2019. (Epub 2019 Nov 12)
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Demeyer, A, Skordos, I, Driege, Y, Kreike, M, Hochepied, T, Baens, M, Staal, J, Beyaert, R. MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner Front Immunol 10, 1898, 2019. (Epub 2019 Aug 14)
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Demeyer, A, Van Nuffel, E, Baudelet, G, Driege, Y, Kreike, M, Muyllaert, D, Staal, J, Beyaert, R. MALT1-Deficient Mice Develop Atopic-Like Dermatitis Upon Aging Front Immunol 10, 2330, 2019. (Epub 2019 Oct 1)
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Dendoncker, K, Timmermans, S, Vandewalle, J, Eggermont, M, Lempiainen, J, Van Hamme, E, Dewaele, S, Vandevyver, S, Ballegeer, M, Souffriau, J, Van Wyngene, L, Van Looveren, K, Vanderhaeghen, T, Beyaert, R, De Bosscher, K, Palvimo, JJ, Van Montagu, M, Libert, C. TNF-alpha inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile Proc Natl Acad Sci U S A 116, 12942-12951, 2019. (Epub 2019 Jun 10)
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Detry, S, Skladanowska, K, Vuylsteke, M, Savvides, SN, Bloch, Y. Revisiting the combinatorial potential of cytokine subunits in the IL-12 family Biochem Pharmacol 165, 240-248, 2019. (Epub 2019 Mar 15)
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de Vasconcelos, NM, Van Opdenbosch, N, Van Gorp, H, Parthoens, E, Lamkanfi, M. Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture Cell Death Differ 26, 146-161, 2019. (Epub 2018 Apr 17)
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de Vasconcelos, NM, Vliegen, G, Goncalves, A, De Hert, E, Martin-Perez, R, Van Opdenbosch, N, Jallapally, A, Geiss-Friedlander, R, Lambeir, AM, Augustyns, K, Van Der Veken, P, De Meester, I, Lamkanfi, M. DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages Life Sci Alliance 2, e201900313, 2019. (Epub 2019 Feb 4)
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De Veirman, K, Menu, E, Maes, K, De Beule, N, De Smedt, E, Maes, A, Vlummens, P, Fostier, K, Kassambara, A, Moreaux, J, Van Ginderachter, JA, De Bruyne, E, Vanderkerken, K, Van Valckenborgh, E. Myeloid-derived suppressor cells induce multiple myeloma cell survival by activating the AMPK pathway Cancer Lett 442, 233-241, 2019. (Epub 2018 Nov 9)
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De Vlaeminck, Y, Lecocq, Q, Giron, P, Heirman, C, Geeraerts, X, Bolli, E, Movahedi, K, Massa, S, Schoonooghe, S, Thielemans, K, Goyvaerts, C, Van Ginderachter, JA, Breckpot, K. Single-domain antibody fusion proteins can target and shuttle functional proteins into macrophage mannose receptor expressing macrophages J Control Release 299, 107-120, 2019. (Epub 2019 Feb 21)
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Devos, M, Mogilenko, DA, Fleury, S, Gilbert, B, Becquart, C, Quemener, S, Dehondt, H, Tougaard, P, Staels, B, Bachert, C, Vandenabeele, P, Van Loo, G, Staumont-Salle, D, Declercq, W, Dombrowicz, D. Keratinocyte expression of A20/TNFAIP3 controls skin inflammation associated with atopic dermatitis and psoriasis J Invest Dermatol 139, 135-145, 2019. (Epub 2018 Aug 14)
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De Vrieze, J, Louage, B, Deswarte, K, Zhong, Z, De Coen, R, Van Herck, S, Nuhn, L, Frich, CK, Zelikin, A, Lienenklaus, S, Sanders, N, David, S, Lambrecht, B, de Geest, B. Potent lymphatic translocation and spatial control over innate immune activation by polymer-lipid amphiphile conjugates of small molecule TLR7/8 agonists Angew Chem Int Ed Engl 58, 15390-15395, 2019. (Epub 2019 Aug 9)
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Dimitrakopoulou, D, Tulkens, D, Van Vlierberghe, P, Vleminckx, K. Xenopus tropicalis: Joining the Armada in the Fight Against Blood Cancer Frontiers in Physiology 10, 48, 2019. (Epub 2019 Feb 1)
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Dondelinger, Y, Delanghe, T, Priem, D, Wynosky-Dolfi, MA, Sorobetea, D, Rojas-Rivera, D, Giansanti, P, Roelandt, R, Gropengiesser, J, Ruckdeschel, K, Savvides, SN, Heck, AJR, Vandenabeele, P, Brodsky, IE, Bertrand, MJM. Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation Nat Commun 10, 1729, 2019. (Epub 2019 Apr 15)
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Doornaert, M, De Maere, E, Colle, J, Declercq, H, Taminau, J, Lemeire, K, Berx, G, Blondeel, P. Xenogen-free isolation and culture of human adipose mesenchymal stem cells Stem Cell Res 40, 101532, 2019. (Epub 2019 Aug 8)
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Doornaert, M, Depypere, B, Creytens, D, Declercq, H, Taminau, J, Lemeire, K, Monstrey, S, Berx, G, Blondeel, P. Human decellularized dermal matrix seeded with adipose-derived stem cells enhances wound healing in a murine model: Experimental study Ann Med Surg (Lond) 46, 4-11, 2019. (Epub 2019 Aug 7)
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Drutman, SB, Haerynck, F, Zhong, FL, Hum, D, Hernandez, NJ, Belkaya, S, Rapaport, F, de Jong, SJ, Creytens, D, Tavernier, SJ, Bonte, K, De Schepper, S, van der Werff Ten Bosch, J, Lorenzo-Diaz, L, Wullaert, A, Bossuyt, X, Orth, G, Bonagura, VR, Beziat, V, et al.. Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form of recurrent respiratory papillomatosis Proc Natl Acad Sci U S A 116, 19055-19063, 2019. (Epub 2019 Sep 4)
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Dubois, H, Sorgeloos, F, Sarvestani, ST, Martens, L, Saeys, Y, Mackenzie, JM, Lamkanfi, M, van Loo, G, Goodfellow, I, Wullaert, A. Nlrp3 inflammasome activation and Gasdermin D-driven pyroptosis are immunopathogenic upon gastrointestinal norovirus infection PLoS Pathog 15, e1007709, 2019. (Epub 2019 Apr 24)
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Dubois, H, van Loo, G, Wullaert, A. Nucleic Acid Induced Interferon and Inflammasome Responses in Regulating Host Defense to Gastrointestinal Viruses Int Rev Cell Mol Biol 345, 137-171, 2019. (Epub 2018 Oct 3)
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Durham, BH, Lopez Rodrigo, E, Picarsic, J, Abramson, D, Rotemberg, V, De Munck, S, Pannecoucke, E, Lu, SX, Pastore, A, Yoshimi, A, Mandelker, D, Ceyhan-Birsoy, O, Ulaner, GA, Walsh, M, Yabe, M, Petrova-Drus, K, Arcila, ME, Ladanyi, M, Solit, DB, et al.. Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms Nat Med 25, 1839-1842, 2019. (Epub 2019 Nov 25)
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Elvas, F, Vanden Berghe, T, Adriaenssens, Y, Vandenabeele, P, Augustyns, K, Staelens, S, Stroobants, S, Van der Veken, P, Wyffels, L. Caspase-3 probes for PET imaging of apoptotic tumor response to anticancer therapy Org Biomol Chem 17, 4801-4824, 2019. (Epub 2019 Apr 29)
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Emmaneel, A, Bogaert, DJ, Van Gassen, S, Tavernier, SJ, Dullaers, M, Haerynck, F, Saeys, Y. A Computational Pipeline for the Diagnosis of CVID Patients Frontiers in Immunology 10, 2009, 2019. (Epub 2019 Aug 30)
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