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Selected IRC publications

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Bousquet, J, Hellings, PW, Agache, I, Bedbrook, A, Bachert, C, Bergmann, KC, Bewick, M, Bindslev-Jensen, C, Bosnic-Anticevitch, S, Bucca, C, Caimmi, DP, Camargos, PA, Canonica, GW, Casale, T, et al., Lambrecht, BN , Cruz, AA, De Carlo, G, Dahl, R, Demoly, P, et al..
ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle
Clin Transl Allergy 6, 47, 2016. (Epub 2016 Dec 30)

Bousquet, J, Schunemann, HJ, Hellings, PW, Arnavielhe, S, Bachert, C, Bedbrook, A, Bergmann, KC, Bosnic-Anticevich, S, Brozek, J, Calderon, M, Canonica, GW, Casale, TB, Chavannes, NH, Cox, L, Chrystyn, H, Cruz, AA, Dahl, R, De Carlo, G, Demoly, P, Lambrecht, B, et al..
MACVIA clinical decision algorithm in adolescents and adults with allergic rhinitis
J Allergy Clin Immunol 138, 367-374, 2016. (Epub 2016 Apr 23)

Brackman, G, Breyne, K, De Rycke, R, Vermote, A, Van Nieuwerburgh, F, Meyer, E, Van Calenbergh, S, Coenye, T.
The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release
Sci Rep 6, 20321, 2016. (Epub 2016 Feb 1)

Bredan, A, Benamer, HT, Bakoush, O.
Why should you choose to publish in the Libyan Journal of Medicine?
Libyan J Med 11, 32756, 2016. (Epub 2016 Jul 21)

Canli, O, Alankus, YB, Grootjans, S, Vegi, N, Hultner, L, Hoppe, PS, Schroeder, T, Vandenabeele, P, Bornkamm, GW, Greten, FR.
Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors
Blood 127, 139-148, 2016. (Epub 2015 Oct 13)

Cannoodt, R, Saelens, W, Saeys, Y.
Computational methods for trajectory inference from single-cell transcriptomics
Eur J Immunol 46, 2496-2506, 2016. (Epub 2016 Sep 28)

Carceller, E, Ballegeer, M, Deckers, J, Riccardi, C, Bruscoli, S, Hochepied, T, Libert, C, Perez, P.
Overexpression of Glucocorticoid-induced Leucine Zipper (GILZ) increases susceptibility to Imiquimod-induced psoriasis and involves cutaneous activation of TGF-beta1
Sci Rep 6, 38825, 2016. (Epub 2016 Dec 9)

Carron, P, Lambert, B, Van Praet, L, De Vos, F, Varkas, G, Jans, L, Elewaut, D, Van den Bosch, F.
Scintigraphic detection of TNF-driven inflammation by radiolabelled certolizumab pegol in patients with rheumatoid arthritis and spondyloarthritis
RMD Open 2, e000265, 2016. (Epub 2016 Jun 24)

Catrysse, L, Farhang Ghahremani, M, Vereecke, L, Youssef, SA, Mc Guire, C, Sze, M, Weber, A, Heikenwalder, M, de Bruin, A, Beyaert, R, van Loo, G.
A20 prevents chronic liver inflammation and cancer by protecting hepatocytes from death
Cell Death Dis 7, e2250, 2016. (Epub 2016 Jun 2)

Cleenewerck, M, Grootaert, MO, Gladysz, R, Adriaenssens, Y, Roelandt, R, Joossens, J, Lambeir, AM, De Meyer, GR, Declercq, W, Augustyns, K, Martinet, W, Van der Veken, P.
Inhibitor screening and enzymatic activity determination for autophagy target Atg4B using a gel electrophoresis-based assay
Eur J Med Chem 123, 631-638, 2016. (Epub 2016 Jul 31)

Conrad, M, Angeli, JP, Vandenabeele, P, Stockwell, BR.
Regulated necrosis: disease relevance and therapeutic opportunities
Nat Rev Drug Discov 15, 348-366, 2016. (Epub 2016 Jan 18)

Cypers, H, Varkas, G, Beeckman, S, Debusschere, K, Vogl, T, Roth, J, Drennan, MB, Lavric, M, Foell, D, Cuvelier, CA, De Vos, M, Delanghe, J, Van den Bosch, F, Elewaut, D.
Elevated calprotectin levels reveal bowel inflammation in spondyloarthritis
Ann Rheum Dis 75, 1357-1362, 2016. (Epub 2015 Dec 23)

Davison, A, McDowell, GaryS, Holden, JenniferM, Johnson, HarrietF, Koutsovoulos, GeorgiosD, Liu, MM, Hulpiau, P, VanRoy, F, Wade, ChristopherM, Banerjee, R, Yang, F, Chiba, S, Davey, JohnW, Jackson, DanielJ, Levin, M, Blaxter, MarkL.
Formin Is Associated with Left-Right Asymmetry in the Pond Snail and the Frog
Current Biology 26, 1-7, 2016. (Epub 2016 Mar 7)

De Beuckelaer, A, Pollard, C, Van Lint, S, Roose, K, Van Hoecke, L, Naessens, T, Udhayakumar, VK, Smet, M, Sanders, N, Lienenklaus, S, Saelens, X, Weiss, S, Vanham, G, Grooten, J, De Koker, S.
Type I interferons interfere with the capacity of mRNA lipoplex vaccines to elicit cytolytic T cell responses
Mol Ther 24, 2012-2020, 2016. (Epub 2016 Aug 10)

Debeuf, N, Haspeslagh, E, van Helden, M, Hammad, H, Lambrecht, BN.
Mouse Models of Asthma
Curr Protoc Mouse Biol 6, 169-184, 2016. (Epub 2016 Jun 1)

De Bock, M, Van Haver, V, Vandenbroucke, RE, Decrock, E, Wang, N, Leybaert, L.
Into rather unexplored terrain-transcellular transport across the blood-brain barrier
Glia 64, 1097-1123, 2016. (Epub 2016 Feb 8)

De Bosscher, K, Beck, IM, Ratman, D, Berghe, WV, Libert, C.
Activation of the Glucocorticoid Receptor in Acute Inflammation: the SEDIGRAM Concept
Trends Pharmacol Sci 37, 4-16, 2016. (Epub 2015 Oct 22)

Debusschere, K, Lories, RJ, Elewaut, D.
MAIT cells: not just another brick in the wall
Ann Rheum Dis 75, 2057-2059, 2016. (Epub 2016 Jul 29)

De Coen, R, Vanparijs, N, Risseeuw, MD, Lybaert, L, Louage, B, De Koker, S, Kumar, V, Grooten, J, Taylor, L, Ayres, N, Van Calenbergh, S, Nuhn, L, De Geest, BG.
pH-degradable mannosylated nanogels for dendritic cell targeting
Biomacromolecules 17, 2479-2488, 2016. (Epub 2016 May 26)

De Groote, P, Grootjans, S, Lippens, S, Eichperger, C, Leurs, K, Kahr, I, Tanghe, G, Bruggeman, I, De Schamphelaire, W, Urwyler, C, Vandenabeele, P, Haustraete, J, Declercq, W.
Generation of a new Gateway-compatible inducible lentiviral vector platform allowing easy derivation of co-transduced cells
Biotechniques 60, 252-259, 2016. (Epub 2016 May 1)

de Kleer, IM, Kool, M, de Bruijn, MJ, Willart, M, van Moorleghem, J, Schuijs, MJ, Plantinga, M, Beyaert, R, Hams, E, Fallon, PG, Hammad, H, Hendriks, RW, Lambrecht, BN.
Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung
Immunity 45, 1285-1298, 2016. (Epub 2016 Dec 5)

Demeestere, D, Dejonckheere, E, Steeland, S, Hulpiau, P, Haustraete, J, Devoogdt, N, Wichert, R, Becker-Pauly, C, Van Wonterghem, E, Dewaele, S, Van Imschoot, G, Aerts, J, Arckens, L, Saeys, Y, Libert, C, Vandenbroucke, RE.
Development and validation of a small single domain antibody that effectively inhibits matrix metalloproteinase 8
Mol Ther 24, 890-902, 2016. (Epub 2016 Jan 18)

Demeyer, A, Staal, J, Beyaert, R.
Targeting MALT1 Proteolytic Activity in Immunity, Inflammation and Disease: Good or Bad?
Trends Mol Med 22, 135-150, 2016. (Epub 2016 Jan 16)

De Mits, S, Lenaerts, J, Vander Cruyssen, B, Mielants, H, Westhovens, R, Durez, P, Elewaut, D, Be-Raise study, g.
A Nationwide Survey on Patient's versus Physician s Evaluation of Biological Therapy in Rheumatoid Arthritis in Relation to Disease Activity and Route of Administration: The Be-Raise Study
PLoS One 11, e0166607, 2016. (Epub 2016 Nov 28)

De Pauw, A, Massion, P, Sekkali, B, Andre, E, Dubroca, C, Kmecova, J, Bouzin, C, Friart, A, Sibille, C, Gilon, P, De Mulder, D, Esfahani, H, Strapart, A, Martherus, R, Payen, V, Sonveaux, P, Brouckaert, P, Janssens, S, Balligand, JL.
Paracrine nitric oxide induces expression of cardiac sarcomeric proteins in adult progenitor cells through soluble guanylyl cyclase/cyclic-guanosine monophosphate and Wnt/beta-catenin inhibition
Cardiovasc Res 112, 478-490, 2016. (Epub 2016 Aug 12)

De Samber, B, Niemiec, MJ, Laforce, B, Garrevoet, J, Vergucht, E, De Rycke, R, Cloetens, P, Urban, CF, Vincze, L.
Probing Intracellular Element Concentration Changes during Neutrophil Extracellular Trap Formation Using Synchrotron Radiation Based X-Ray Fluorescence
PLoS One 11, e0165604, 2016. (Epub 2016 Nov 3)

De Schryver, E, Calus, L, Bonte, H, Natalie, R, Gould, H, Donovan, E, Elewaut, D, Valenta, R, Mittermann, I, Gutermuth, J, Seher, T, Schleimer, RP, Tan, BK, Derycke, L, Van Zele, T, Bachert, C, Gevaert, P.
The quest for autoreactive antibodies in nasal polyps
J Allergy Clin Immunol 138, 893895e5, 2016. (Epub 2016 May 6)

de Vasconcelos, NM, Van Opdenbosch, N, Lamkanfi, M.
Inflammasomes as polyvalent cell death platforms
Cell Mol Life Sci 73, 2335-2347, 2016. (Epub 2016 Apr 5)

Dondelinger, Y, Darding, M, Bertrand, MJ, Walczak, H.
Poly-ubiquitination in TNFR1-mediated necroptosis
Cell Mol Life Sci 73, 21652176, 2016. (Epub 2016 Apr 11)

Dondelinger, Y, Hulpiau, P, Saeys, Y, Bertrand, MJ, Vandenabeele, P.
An evolutionary perspective on the necroptotic pathway
Trends Cell Biol 26, 721-732, 2016. (Epub 2016 Jun 28)

Dondelinger, Y, Vandenabeele, P, Bertrand, MJ.
Regulation of RIPK1's cell death function by phosphorylation
Cell Cycle 15, 5-6, 2016. (Epub 2015 Oct 30)

Dordea, AC, Vandenwijngaert, S, Garcia, V, Tainsh, RE, Nathan, DI, Allen, K, Raher, MJ, Tainsh, LT, Zhang, FF, Lieb, WS, Mikelman, S, Kirby, A, Stevens, C, Thoonen, R, Hindle, AG, Sips, PY, Falck, JR, Daly, MJ, Brouckaert, P, et al..
Androgen-Sensitive Hypertension Associated with Soluble Guanylate Cyclase Alpha1 Deficiency Is Mediated by 20-Hete
Am J Physiol Heart Circ Physiol 310, H1790-H1800, 2016. (Epub 2016 May 3)

Drechsler, S, Lynch, MA, Novella, S, Gonzalez-Navarro, H, Hecimovic, S, Barini, E, Tucci, V, Castro, RE, Vandenbroucke, RE, Osuchowski, M, Potter, PK.
With mouse age comes wisdom: a review and suggestions of relevant mouse models for age-related conditions
Mech Ageing Dev 160, 54-68, 2016. (Epub 2016 Jul 20)

Drennan, MB, Govindarajan, S, Verheugen, E, Coquet, JM, Staal, J, McGuire, C, Taghon, T, Leclercq, G, Beyaert, R, van Loo, G, Lambrecht, BN, Elewaut, D.
NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20
J Exp Med 213, 1973-1981, 2016. (Epub 2016 Aug 22)

Dubois, H, Wullaert, A, Lamkanfi, M.
General Strategies in Inflammasome Biology
Curr Top Microbiol Immunol 397, 1-22, 2016. (Epub 2016 Jul 27)

Elton, L, Carpentier, I, Staal, J, Driege, Y, Haegman, M, Beyaert, R.
MALT1 cleaves the E3 ubiquitin ligase HOIL-1 in activated T cells, generating a dominant negative inhibitor of LUBAC-induced NF-kappaB signaling
FEBS J 283, 403-412, 2016. (Epub 2015 Nov 17)

Exley, MA, Tsokos, GC, Mills, KH, Elewaut, D, Mulhearn, B.
What rheumatologists need to know about innate lymphocytes
Nat Rev Rheumatol 12, 658-668, 2016. (Epub 2016 Sep 2)

Faura Tellez, G, Willemse, BW, Brouwer, U, Nijboer-Brinksma, S, Vandepoele, K, Noordhoek, JA, Heijink, I, de Vries, M, Smithers, NP, Postma, DS, Timens, W, Wiffen, L, van Roy, F, Holloway, JW, Lackie, PM, Nawijn, MC, Koppelman, GH.
Protocadherin-1 Localization and Cell-Adhesion Function in Airway Epithelial Cells in Asthma
PLoS One 11, e0163967, 2016. (Epub 2016 Oct 4)

Favreau, M, Vanderkerken, K, Elewaut, D, Venken, K, Menu, E.
Does an NKT-cell-based immunotherapeutic approach have a future in multiple myeloma?
Oncotarget 7, 23128-23140, 2016. (Epub 2016 Feb 17)

Felix, J, Kandiah, E, De Munck, S, Bloch, Y, van Zundert, GC, Pauwels, K, Dansercoer, A, Novanska, K, Read, RJ, Bonvin, AM, Vergauwen, B, Verstraete, K, Gutsche, I, Savvides, SN.
Structural basis of GM-CSF and IL-2 sequestration by the viral decoy receptor GIF
Nat Commun 7, 13228, 2016. (Epub 2016 Nov 7)

Filliol, A, Piquet-Pellorce, C, Le Seyec, J, Farooq, M, Genet, V, Lucas-Clerc, C, Bertin, J, Gough, PJ, Dimanche-Boitrel, MT, Vandenabeele, P, Bertrand, MJ, Samson, M.
RIPK1 protects from TNF-alpha-mediated liver damage during hepatitis
Cell Death Dis 7, e2462, 2016. (Epub 2016 Nov 10)

Filtjens, J, Keirsse, J, Van Ammel, E, Taveirne, S, Van Acker, A, Kerre, T, Taghon, T, Vandekerckhove, B, Plum, J, Van Ginderachter, JA, Leclercq, G.
Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours
Sci Rep 6, 30564, 2016. (Epub 2016 Jul 29)

Folmsbee, SS, Wilcox, DR, Tyberghein, K, De Bleser, P, Tourtellotte, WG, van Hengel, J, van Roy, F, Gottardi, CJ.
alphaT-catenin in restricted brain cell types and its potential connection to autism
J Mol Psychiatry 4, 2, 2016. (Epub 2016 Jun 21)

Fukaya, M, Brorsson, CA, Meyerovich, K, Catrysse, L, Delaroche, D, Vanzela, EC, Ortis, F, Beyaert, R, Nielsen, LB, Andersen, ML, Mortensen, HB, Pociot, F, van Loo, G, St Rling, J, Cardozo, AK.
A20 inhibits beta-cell Apoptosis by Multiple Mechanisms and Predicts Residual beta-cell Function in Type 1 Diabetes
Mol Endocrinol 30, 48-61, 2016. (Epub 2015 Dec 10)

Garg, AD, Krysko, DV, Vandenabeele, P, Agostinis, P.
Extracellular ATP and P2X7 receptor exert context-specific immunogenic effects after immunogenic cancer cell death
Cell Death Dis 7, e2097, 2016. (Epub 2016 Feb 18)

Geeraerts, E, Dekeyster, E, Gaublomme, D, Salinas-Navarro, M, De Groef, L, Moons, L.
A freely available semi-automated method for quantifying retinal ganglion cells in entire retinal flatmounts
Exp Eye Res 147, 105-113, 2016. (Epub 2016 Apr 20)

Ginhoux, F, Guilliams, M.
Tissue-Resident Macrophage Ontogeny and Homeostasis
Immunity 44, 439-449, 2016. (Epub 2016 Mar 15)

Ginhoux, F, Guilliams, M, Naik, SH.
Editorial: Dendritic Cell and Macrophage Nomenclature and Classification
Front Immunol 7, 168, 2016. (Epub 2016 May 2)

Godar, M, Lambrecht, BN.
A New aDENNDum to Genetics of Childhood Asthma
Cell 164, 11-13, 2016. (Epub 2016 Jan 14)

Godar, M, Morello, V, Sadi, A, Hultberg, A, De Jonge, N, Basilico, C, Hanssens, V, Saunders, M, Lambrecht, BN, El Khattabi, M, de Haard, H, Michieli, P, Blanchetot, C.
Dual anti-idiotypic purification of a novel, native-format biparatopic anti-MET antibody with improved in vitro and in vivo efficacy
Sci Rep 6, 31621, 2016. (Epub 2016 Aug 22)

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