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Publications from this research unit
This page shows only publications with IRC as the affiliation of at least one author.
Publications by IRC members mentioning other affiliations are not in our database. Sorry.
See "Extra muros" papers of the units.
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Scott, CL, Soen, B, Martens, L, Skrypek, N, Saelens, W, Taminau, J, Blancke, G, Van Isterdael, G, Huylebroeck, D, Haigh, J, Saeys, Y, Guilliams, M, Lambrecht, BN, Berx, G. The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2 J Exp Med 213, 897-911, 2016. (Epub 2016 May 16) 
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Andries, V, Vandepoele, K, Staes, K, Berx, G, Bogaert, P, Van Isterdael, G, Ginneberge, D, Parthoens, E, Vandenbussche, J, Gevaert, K, van Roy, F. NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest BMC Cancer 15, 391, 2015. (Epub 2015 May 10)
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Ballantyne, LL, Sin, YY, St Amand, T, Si, J, Goossens, S, Haenebalcke, L, Haigh, JJ, Kyriakopoulou, L, Schulze, A, Funk, CD. Strategies to rescue the consequences of inducible arginase-1 deficiency in mice PLoS One 10, e0125967, 2015. (Epub 2015 May 4)
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De Vlieghere, E, Gremonprez, F, Verset, L, Mariën, L, Jones, CJ, De Craene, B, Berx, G, Descamps, B, Vanhove, C, Remon, J-P, Ceelen, W, Demetter, P, Bracke, M, De Geest, BG, De Wever, O. Tumor-environment biomimetics delay peritoneal metastasis formation by deceiving and redirecting disseminated cancer cells Biomaterials 54, 148-157, 2015. (Epub 2015 Mar 4)
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Durinck, K, Goossens, S, Peirs, S, Wallaert, A, Van Loocke, W, Matthijssens, F, Pieters, T, Milani, G, Lammens, T, Rondou, P, Van Roy, N, De Moerloose, B, Benoit, Y, Haigh, J, Speleman, F, Poppe, B, Van Vlierberghe, P. Novel biological insights in T-cell acute lymphoblastic leukemia Exp Hematol 43, 625-639, 2015. (Epub 2015 Jun 26)
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Goossens, S, Radaelli, E, Blanchet, O, Durinck, K, Van der Meulen, J, Peirs, S, Taghon, T, Tremblay, CS, Costa, M, Farhang Ghahremani, M, De Medts, J, Bartunkova, S, Haigh, K, Schwab, C, Farla, N, Pieters, T, Matthijssens, F, Van Roy, N, Best, JA, et al.. ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling Nat Commun 6, 5794, 2015. (Epub 2015 Jan 7)
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Horvay, K, Jarde, T, Casagranda, F, Perreau, VM, Haigh, K, Nefzger, CM, Akhtar, R, Gridley, T, Berx, G, Haigh, JJ, Barker, N, Polo, JM, Hime, GR, Abud, HE. Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium EMBO J 34, 1319-1335, 2015. (Epub 2015 Mar 10)
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Omilusik, KD, Best, JA, Yu, B, Goossens, S, Weidemann, A, Nguyen, JV, Seuntjens, E, Stryjewska, A, Zweier, C, Roychoudhuri, R, Gattinoni, L, Bird, LM, Higashi, Y, Kondoh, H, Huylebroeck, D, Haigh, J, Goldrath, AW. Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection J Exp Med 212, 2027-2039, 2015. (Epub 2015 Oct 26)
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Ramboer, E, De Craene, B, De Kock, J, Berx, G, Rogiers, V, Vanhaecke, T, Vinken, M. Development and chararcterization of a new human hepatic cell line Excli Journal 14, 875-889, 2015. (Epub 2015 Jul 28)
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Van der Meulen, J, Sanghvi, V, Mavrakis, K, Durinck, K, Fang, F, Matthijssens, F, Rondou, P, Rosen, M, Pieters, T, Vandenberghe, P, Delabesse, E, Lammens, T, De Moerloose, B, Menten, B, Van Roy, N, Verhasselt, B, Poppe, B, Benoit, Y, Taghon, T, et al.. The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia Blood 125, 13-21, 2015. (Epub 2014 Oct 15)
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van Helden, MJ, Goossens, S, Daussy, C, Mathieu, AL, Faure, F, Marcais, A, Vandamme, N, Farla, N, Mayol, K, Viel, S, Degouve, S, Debien, E, Seuntjens, E, Conidi, A, Chaix, J, Mangeot, P, de Bernard, S, Buffat, L, Haigh, JJ, et al.. Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection J Exp Med 212, 2015-2025, 2015. (Epub 2015 Oct 26)
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Castiglioni, V, Farhang Ghahremani, M, Goossens, S, De Maglie, M, Ardizzone, M, Haigh, JJ, Radaelli, E. Immunohistological description of nongestational ovarian choriocarcinoma in two female mice with conditional loss of Trp53 driven by the Tie2 promoter Vet Pathol 52, 752-756, 2014. (Epub 2014 Sep 24)
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De Craene, B, Denecker, G, Vermassen, P, Taminau, J, Mauch, C, Derore, A, Jonkers, J, Fuchs, E, Berx, G. Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential Cell Death Differ 21, 310-320, 2014. (Epub 2013 Oct 25)
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De Groote, P, Tran, HT, Fransen, M, Tanghe, G, Urwyler, C, De Craene, B, Leurs, K, Gilbert, B, Van Imschoot, G, De Rycke, R, Guerin, CJ, Holland, P, Berx, G, Vandenabeele, P, Lippens, S, Vleminckx, K, Declercq, W. A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes Cell Death Differ 22, 1012-1024, 2014. (Epub 2014 Nov 28)
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Denecker, G, Vandamme, N, Akay, Ö, Koludrovic, D, Taminau, J, Lemeire, K, Gheldof, A, De Craene, B, Van Gele, M, Brochez, L, Udupi, G, Rafferty, M, Balint, B, Gallagher, WM, Ghanem, G, Huylebroeck, D, Haigh, JJ, van den Oord, J, Larue, L, Davidson, I, Marine, JC, Berx, G. Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression Cell Death Differ 21, 1250-1261, 2014. (Epub 2014 Apr 25)
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Farhang Ghahremani, M, Radaelli, E, Haigh, K, Bartunkova, S, Haenebalcke, L, Marine, JC, Goossens, S, Haigh, JJ. Loss of autocrine endothelial-derived VEGF significantly reduces hemangiosarcoma development in conditional p53-deficient mice Cell Cycle 13, 1501-1507, 2014. (Epub 2014 Mar 11)
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Goossens, S, Van Vlierberghe, P. Controlling Pre-leukemic Thymocyte Self-Renewal PLoS Genet 10, e1004881, 2014. (Epub 2014 Dec 18)
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Mets, E, Van der Meulen, J, Van Peer, G, Boice, M, Mestdagh, P, Van de Walle, I, Lammens, T, Goossens, S, De Moerloose, B, Benoit, Y, Van Roy, N, Clappier, E, Poppe, B, Vandesompele, J, Wendel, HG, Taghon, T, Rondou, P, Soulier, J, Van Vlierberghe, P, Speleman, F. MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemia Leukemia 29, 798-806, 2014. (Epub 2014 Sep 18)
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Mets, E, Van Peer, G, Van der Meulen, J, Boice, M, Taghon, T, Goossens, S, Mestdagh, P, Benoit, Y, De Moerloose, B, Van Roy, N, Poppe, B, Vandesompele, J, Wendel, HG, Van Vlierberghe, P, Speleman, F, Rondou, P. MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia Haematologica 99, 1326-1333, 2014. (Epub 2014 Jun 3)
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Peirs, S, Matthijssens, F, Goossens, S, Van de Walle, I, Ruggero, K, de Bock, CE, Degryse, S, Cante-Barrett, K, Briot, D, Clappier, E, Lammens, T, De Moerloose, B, Benoit, Y, Poppe, B, Meijerink, J, Cools, J, Soulier, J, Rabbitts, TH, Taghon, T, Speleman, F, Van Vlierberghe, P. ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia Blood 124, 3738-3747, 2014. (Epub 2014 Oct 9)
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Quimbaya, M, Raspe, E, Denecker, G, De Craene, B, Roelandt, R, Declercq, W, Sagaert, X, De Veylder, L, Berx, G. Deregulation of the replisome factor MCMBP prompts oncogenesis in colorectal carcinomas through chromosomal instability Neoplasia 16, 694-709, 2014. (Epub 2014 Sep)
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Ramboer, E, De Craene, B, De Kock, J, Vanhaecke, T, Berx, G, Rogiers, V, Vinken, M. Strategies for immortalization of primary hepatocytes J Hepatol 61, 925-943, 2014. (Epub 2014 Jun 6)
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Tatari, MN, De Craene, B, Soen, B, Taminau, J, Vermassen, P, Goossens, S, Haigh, K, Cazzola, S, Lambert, J, Huylebroeck, D, Haigh, JJ, Berx, G. ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins Cell Mol Life Sci 71, 3599-3609, 2014. (Epub 2014 Feb 27)
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Vandamme, N, Berx, G. Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity Front Oncol 4, 1-6, 2014. (Epub 2014 Dec 9)
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De Craene, B, Berx, G. Regulatory networks defining EMT during cancer initiation and progression Nat Rev Cancer 13, 97-110, 2013. (Epub 2013 Jan 24)
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Gheldof, A, Berx, G. Cadherins and epithelial-to-mesenchymal transition In Progress in molecular biology and translational science: The molecular biology of cadherins. (Van Roy, F, ed.), Burlington, Academic Press , pp. 317-336, 2013. (Epub 2013 Mar)
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Koopmansch, B, Berx, G, Foidart, JM, Gilles, C, Winkler, R. Interplay between KLF4 and ZEB2/SIP1 in the regulation of E-cadherin expression Biochem Biophys Res Commun 431, 652-657, 2013. (Epub 2013 Jan 29)
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van den Berghe, V, Stappers, E, Vandesande, B, Dimidschstein, J, Kroes, R, Francis, A, Conidi, A, Lesage, F, Dries, R, Cazzola, S, Berx, G, Kessaris, N, Vanderhaeghen, P, van IJcken, W, Grosveld, FG, Goossens, S, Haigh, JJ, Fishell, G, Goffinet, A, Aerts, S, Huylebroeck, D, Seuntjens, E. Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Neuron 77, 70-82, 2013. (Epub 2013 Jan 9)
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Gheldof, A, Hulpiau, P, van Roy, F, De Craene, B, Berx, G. Evolutionary functional analysis and molecular regulation of the ZEB transcription factors Cell Mol Life Sci 69, 2527-2541, 2012. (Epub 2012 Feb 21)
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Quimbaya, M, Vandepoele, K, Raspe, E, Matthijs, M, Dhondt, S, Beemster, GT, Berx, G, De Veylder, L. Identification of putative cancer genes through data integration and comparative genomics between plants and humans Cell Mol Life Sci 69, 2041-2055, 2012. (Epub 2012 Jan 5)
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Raspe, E, Decraene, C, Berx, G. Gene expression profiling to dissect the complexity of cancer biology: Pitfalls and promise Semin Cancer Biol 22, 250-260, 2012. (Epub 2012 Mar 7)
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Sleeman, JP, Christofori, G, Fodde, R, Collard, JG, Berx, G, Decraene, C, Ruegg, C. Concepts of metastasis in flux: The stromal progression model Semin Cancer Biol 22, 174-186, 2012. (Epub 2012 Feb 21)
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Tiwari, N, Gheldof, A, Tatari, M, Christofori, G. EMT as the ultimate survival mechanism of cancer cells Semin Cancer Biol 22, 194-207, 2012. (Epub 2012 Mar 8)
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Goossens, S, Janzen, V, Bartunkova, S, Yokomizo, T, Drogat, B, Crisan, M, Haigh, K, Seuntjens, E, Umans, L, Riedt, T, Bogaert, P, Haenebalcke, L, Berx, G, Dzierzak, E, Huylebroeck, D, Haigh, JJ. The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization Blood 117, 5620-5630, 2011. (Epub 2011 Feb 25)
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Bonnet, E, Tatari, M, Joshi, A, Michoel, T, Marchal, K, Berx, G, Van de Peer, Y. Module network inference from a cancer gene expression data set identifies microRNA regulated modules PLoS One 5, e10162, 2010. (Epub 2010 Apr 14)
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Foubert, E, De Craene, B, Berx, G. Key signalling nodes in mammary gland development and cancer. The Snail1-Twist1 conspiracy in malignant breast cancer progression Breast Cancer Res 12, 206, 2010. (Epub 2010 Jun 25)
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Herfs, M, Hubert, P, Suarez-Carmona, M, Reschner, A, Saussez, S, Berx, G, Savagner, P, Boniver, J, Delvenne, P. Regulation of p63 isoforms by Snail and Slug transcription factors in human squamous cell carcinoma Am J Pathol 176, 1941-1949, 2010. (Epub 2010 Feb 11)
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Takahashi, N, Quimbaya, M, Schubert, V, Lammens, T, Vandepoele, K, Schubert, I, Matsui, M, Inze, D, Berx, G, De Veylder, L. The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair PLoS Genet 6, e1000817, 2010. (Epub 2010 Jan 15)
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Berx, G, Van Roy, F. Involvement of members of the Cadherin superfamily in cancer Cold Spring Harbor Perspect Biol 1, a003129, 2009. (Epub 2009 Sep 23)
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Marine, JC, Berx, G. Transforming growth factor-beta and mutant p53 conspire to induce metastasis by antagonizing p63: a (ternary) complex affair Breast Cancer Res 11, 304, 2009. (Epub ---)
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Nyabi, O, Naessens, M, Haigh, K, Gembarska, A, Goossens, S, Maetens, M, De Clercq, S, Drogat, B, Haenebalcke, L, Bartunkova, S, De Vos, I, De Craene, B, Karimi, M, Berx, G, Nagy, A, Hilson, P, Marine, JC, Haigh, JJ. Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells Nucleic Acids Res 37, e55, 2009. (Epub ---)
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Van den Bossche, J, Bogaert, P, van Hengel, J, Guerin, CJ, Berx, G, Movahedi, K, Van den Bergh, R, Pereira-Fernandes, A, Geuns, JM, Pircher, H, Dorny, P, Grooten, J, De Baetselier, P, Van Ginderachter, JA. Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes Blood 114, 4664-4674, 2009. (Epub 2009 Sep 2)
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Vandewalle, C, Van Roy, F, Berx, G. The role of the ZEB family of transcription factors in development and disease Cell Mol Life Sci 66, 773-787, 2009. (Epub 2008 Nov 17)
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Bonnomet, A, Polette, M, Strumane, K, Gilles, C, Dalstein, V, Kiletzky, C, Berx, G, van Roy, F, Birembaut, P, Nawrocki-Raby, B. The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression. Oncogene 27, 3692-3699, 2008. (Epub 2008 Jan 28)
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De Wever, O, Pauwels, P, De Craene, B, Sabbah, M, Emami, S, Redeuilh, G, Gespach, C, Bracke, M, Berx, G. Molecular and pathological signatures of epithelial-mesenchymal transitions at the cancer invasion front Histochem Cell Biol 130, 481-494, 2008. (Epub 2008 Jul 22)
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Herfs, M, Hubert, P, Kholod, N, Caberg, JH, Gilles, C, Berx, G, Savagner, P, Boniver, J, Delvenne, P. Transforming growth factor-beta 1-mediated slug and snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression Am J Pathol 172, 1391-1402, 2008. (Epub 2008 Apr 1)
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Stemmer, V, de Craene, B, Berx, G, Behrens, J. Snail promotes Wnt target gene expression and interacts with beta-catenin Oncogene 27, 5075-5080, 2008. (Epub ---)
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Vandepoele, K, Andries, V, Van Roy, N, Staes, K, Vandesompele, J, Laureys, G, De Smet, E, Berx, G, Speleman, S, van Roy, F. A constitutional translocation t(1;17)(p36.2;q11.2) in a neuroblastoma patient disrupts the human NBPF1 and ACCN1 genes PLoS One 3, e2207, 2008. (Epub 2008 May 21)
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Van Roy, F, Berx, G. The cell-cell adhesion molecule E-cadherin Cell Mol Life Sci 65, 3756-3788, 2008. (Epub 2008 Aug 23)
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Berx, G, Raspe, E, Christofori, G, Thiery, JP, Sleeman, JP. Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer Clin Exp Metastasis 24, 587-597, 2007. (Epub 2007 Nov 3)
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