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Mc Guire, C, Beyaert, R, van Loo, G.
Death receptor signalling in central nervous system inflammation and demyelination
Trends Neurosci 34, 619-628, 2011. (Epub 2011 Oct 13)

Raasch, J, Zeller, N, van Loo, G, Merkler, D, Mildner, A, Erny, D, Knobeloch, KP, Bethea, JR, Waisman, A, Knust, M, Del Turco, D, Deller, T, Blank, T, Priller, J, Brück, W, Pasparakis, M, Prinz, M.
IkB kinase 2 determines oligodendrocyte loss by non cell-autonomous activation of NF-kB in the central nervous system
Brain 134, 1184-1198, 2011. (Epub 2011 Feb 10)

van Loo, G, Beyaert, R.
Negative regulation of NF-kappaB and its involvement in rheumatoid arthritis
Arthritis Res Ther 13, 221, 2011. (Epub 2011 May 31)

Vereecke, L, Beyaert, R, van Loo, G.
Enterocyte death and intestinal barrier maintenance in homeostasis and disease
Trends Mol Med 17, 584-593, 2011. (Epub 2011 Jul 6)

Vereecke, L, Beyaert, R, van Loo, G.
Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimmune disease
Biochem Soc Trans 39, 1086-1091, 2011. (Epub 2011 Aug 1)

Welz, P-S, Wullaert, A, Vlantis, K, Kondylis, V, Fernandez-Majada, V, Ermolaeva, M, Kirsch, P, Sterner-Kock, A, van Loo, G, Pasparakis, M.
FADD prevents RIP3-mediated epithelial cell necroptosis and chronic intestinal inflammation
Nature 477, 330-334, 2011. (Epub 2011 Jul 31)

Mc Guire, C, Volckaert, T, Wolke, U, Sze, M, De Rycke, R, Waisman, A, Prinz, M, Beyaert, R, Pasparakis, M, van Loo, G.
Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination
J Immunol 185, 7646-7653, 2010. (Epub 2010 Nov 10)

van Loo, G, Sze, M, Bougarne, N, Praet, J, McGuire, C, Ullrich, A, Haegeman, G, Prinz, M, Beyaert, R, De Bosscher, K.
Anti-inflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor (GR) modulator in experimental autoimmune encephalomyelitis
Mol Endocrinol 24, 310-322, 2010. (Epub 2009 Dec 4)

Vereecke, L, Sze, M, Mc Guire, C, Rogiers, B, Chu, Y, Schmidt-Supprian, M, Pasparakis, M, Beyaert, R, van Loo, G.
Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor-induced toxicity and experimental colitis
J Exp Med 207, 1513-1523, 2010. (Epub 2010 Jun 7)

Verstrepen, L, Verhelst, K, van Loo, G, Carpentier, I, Ley, SC, Beyaert, R.
Expression, biological activities and mechanisms of action of A20 (TNFAIP3)
Biochem Pharmacol 80, 2009-2020, 2010. (Epub 2010 Jul 1)

Beyaert, R, Van Loo, G.
Inflammation
In Encyclopedia of Molecular Mechanisms of Disease. (Lang, F, ed.), Richmond, Springer, pp. in press, 2009. (Epub ---)

Derudder, E, Cadera, EJ, Vahl, JC, Wang, J, Fox, CJ, Zha, S, van Loo, G, Pasparakis, M, Schlissel, MS, Schmidt-Supprian, M, Rajewsky, K.
Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals
Nat Immunol 10, 647-654, 2009. (Epub 2009 May 3)

Vereecke, L, Beyaert, R, van Loo, G.
The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology
Trends Immunol 30, 383-391, 2009. (Epub 2009 Jul 28)

Noels, H, van Loo, G, Hagens, S, Broeckx, V, Beyaert, R, Marynen, P, Baens, M.
A novel TRAF6 binding site in MALT1 defines distinct mechanisms of NF-kappa B activation by API2-MALT1 fusions
J Biol Chem 282, 10180-10189, 2007. (Epub 2007 Feb 7)

Wullaert, A, van Loo, G, van Loo, G, Heyninck, K, Beyaert, R.
Hepatic TNF signaling and NF-kappaB: effects on liver homeostasis and beyond
Endocr Rev 28, 365-386, 2007. (Epub 2007 Apr 12)

Cornelis, S, Bruynooghe, Y, van Loo, G, Saelens, X, Vandenabeele, P, Beyaert, R.
Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1
Oncogene 24, 1552-1562, 2005. (Epub ---)

Depuydt, B, van Loo, G, Vandenabeele, P, Declercq, W.
Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors
J Cell Sci 118, 497-504, 2005. (Epub 2005 Jan 18)

Festjens, N, van Gurp, M, van Loo, G, Saelens, X, Vandenabeele, P.
Bcl-2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death
Acta Haematol 111, 7-27, 2004. (Epub ---)

Saelens, X, Festjens, N, Vande Walle, L, van Gurp, M, van Loo, G, Vandenabeele, P.
Toxic proteins released from mitochondria in cell death
Oncogene 23, 2861-2874, 2004. (Epub ---)

Saelens, X, van Loo, G, Gevaert, K, Vandekerckhove, J, Vandenabeele, P.
The use of proteomics to identify and characterize cell death proteins
In: When Cells Die II: A Comprehensive Evaluation of Apoptosis and Programmed Cell Death. (Lockshin, RA, Zakeri, Z, eds.), 2nd ed. Hoboken, Wiley , pp. 405-435, 2004. (Epub ---)

Vanden Berghe, T, van Loo, G, Saelens, X, van Gurp, M, Brouckaert, G, Kalai, M, Declercq, W, Vandenabeele, P.
Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD
J Biol Chem 279, 7925-7933, 2004. (Epub 2003 Dec 10)

Vanden Berghe, T, Kalai, M, van Loo, G, Declercq, W, Vandenabeele, P.
Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis
J Biol Chem 278, 56225629, 2003. (Epub 2002 Nov 18)

van Gurp, M, Festjens, N, van Loo, G, Saelens, X, Vandenabeele, P.
Mitochondrial intermembrane proteins in cell death
Biochem Biophys Res Commun 304, 487-497, 2003. (Epub ---)

van Loo, G, Lippens, S, Hahne, M, Matthijssens, F, Declercq, W, Saelens, X, Vandenabeele, P.
A Bcl-2 transgene expressed in hepatocytes does not protect mice from fulminant liver destruction induced by Fas ligand
Cytokine 22, 62-70, 2003. (Epub ---)

Beyaert, R, van Loo, G, Heyninck, K, Vandenabeele, P.
Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas
Int Rev Cytol 214, 225-272, 2002. (Epub ---)

Kalai, M, van Loo, G, Vanden Berghe, T, Meeus, A, Burm, W, Saelens, X, Vandenabeele, P.
Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA
Cell Death Differ 9, 981-994, 2002. (Epub ---)

van Loo, G, Demol, H, van Gurp, M, Hoorelbeke, B, Schotte, P, Beyaert, R, Zhivotovsky, B, Gevaert, K, Declercq, W, Vandekerckhove, J, Vandenabeele, P.
A matrix-assisted laser desorption ionization post-source decay (MALDI-PSD) analysis of proteins released from isolated liver mitochondria treated with recombinant truncated Bid
Cell Death Differ 9, 301-308, 2002. (Epub ---)

van Loo, G, Saelens, X, Matthijssens, F, Schotte, P, Beyaert, R, Declercq, W, Vandenabeele, P.
Caspases are not localized in mitochondria during life or death
Cell Death Differ 9, 1207-1211, 2002. (Epub ---)

van Loo, G, Saelens, X, van Gurp, M, MacFarlane, M, Martin, SJ, Vandenabeele, P.
The role of mitochondrial factors in apoptosis: A Russian roulette with more than one bullet
Cell Death Differ 9, 1031-1042, 2002. (Epub ---)

van Loo, G, van Gurp, M, Depuydt, B, Srinivasula, SM, Rodriguez, I, Alnemri, ES, Gevaert, K, Vandekerckhove, J, Declercq, W, Vandenabeele, P.
The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity
Cell Death Differ 9, 20-26, 2002. (Epub ---)

Denecker, G, Vercammen, D, Steemans, M, Vanden Berghe, T, Brouckaert, G, van Loo, G, Zhivotovsky, B, Fiers, W, Grooten, J, Declercq, W, Vandenabeele, P.
Death receptor-induced apoptotic and necrotic cell death: Differential role of caspases and mitochondria
Cell Death Differ 8, 829-840, 2001. (Epub ---)

Schotte, P, van Loo, G, Carpentier, I, Vandenabeele, P, Beyaert, R.
Lithium sensitizes tumor cells in an NF-kB-independent way to caspase activation and apoptosis induced by tumor necrosis factor (TNF). Evidence for a role of the TNF receptor-associated death domain protein
J Biol Chem 276, 25939-25945, 2001. (Epub 2001 May 7)

van Loo, G, Schotte, P, van Gurp, M, Demol, H, Hoorelbeke, B, Gevaert, K, Rodriguez, I, Ruiz-Carrillo, A, Vandekerckhove, J, Declercq, W, Beyaert, R, Vandenabeele, P.
Endonuclease G: A mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation
Cell Death Differ 8, 1136-1142, 2001. (Epub ---)

Boone, E, Vanden Berghe, T, van Loo, G, De Wilde, G, De Wael, N, Vercammen, D, Fiers, W, Haegeman, G, Vandenabeele, P.
Structure/function analysis of p55 tumor necrosis factor receptor and Fas-associated death domain. Effect on necrosis in L929sA cells
J Biol Chem 275, 37596-37603, 2000. (Epub ---)

Denecker, G, Dooms, H, van Loo, G, Vercammen, D, Grooten, J, Fiers, W, Declercq, W, Vandenabeele, P.
Phosphatidyl serine exposure during apoptosis precedes release of cytochrome c and decrease in mitochondrial transmembrane potential
FEBS Lett 465, 47-52, 2000. (Epub ---)

Schotte, P, Van Criekinge, W, Van de Craen, M, van Loo, G, Desmedt, M, Grooten, J, Cornelissen, M, De Ridder, L, Vandekerckhove, J, Fiers, W, Vandenabeele, P, Beyaert, R.
Cathepsin B-mediated activation of the proinflammatory caspase-11
Biochem Biophys Res Commun 251, 379-387, 1998. (Epub ---)

Van de Craen, M, van Loo, G, Pype, S, Van Criekinge, W, Van den brande, I, Molemans, F, Fiers, W, Declercq, W, Vandenabeele, P.
Identification of a new caspase homologue: Caspase-14
Cell Death Differ 5, 838-846, 1998. (Epub ---)

Van de Craen, M, van Loo, G, Van den brande, I, Declercq, W, Mandruzzato, S, van der Bruggen, P, Fiers, W, Vandenabeele, P.
Molecular cloning and identification of murine caspase-8
J Mol Biol 284, 1017-1026, 1998. (Epub ---)

Vercammen, D, Beyaert, R, Denecker, G, Goossens, V, van Loo, G, Declercq, W, Grooten, J, Fiers, W, Vandenabeele, P.
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
J Exp Med 187, 1477-1485, 1998. (Epub ---)

Van de Craen, M, Vandenabeele, P, Declercq, W, Van den brande, I, van Loo, G, Molemans, F, Schotte, P, Van Criekinge, W, Beyaert, R, Fiers, W.
Characterization of seven murine caspase family members
FEBS Lett 403, 61-69, 1997. (Epub ---)

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