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de Reuver, R, Verdonck, S, Dierick, E, Nemegeer, J, Hessmann, E, Ahmad, S, Jans, M, Blancke, G, Van Nieuwerburgh, F, Botzki, A, Vereecke, L, van Loo, G, Declercq, W, Hur, S, Vandenabeele, P, Maelfait, J.
ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation
Nature 607, 784-789, 2022. (Epub 2022 Jul 20)

De Schutter, E, Ramon, J, Pfeuty, B, De Tender, C, Stremersch, S, Raemdonck, K, de Beeck, KO, Declercq, W, Riquet, FB, Braeckmans, K, Vandenabeele, P.
Plasma membrane perforation by GSDME during apoptosis-driven secondary necrosis
Cell Mol Life Sci 79, 19, 2022. (Epub 2021 Dec 31)

Fernandez-Acosta, R, Iriarte-Mesa, C, Alvarez-Alminaque, D, Hassannia, B, Wiernicki, B, Diaz-Garcia, AM, Vandenabeele, P, Vanden Berghe, T, Pardo Andreu, GL.
Novel Iron Oxide Nanoparticles Induce Ferroptosis in a Panel of Cancer Cell Lines
Molecules 27, 3970, 2022. (Epub 2022 Jun 21)

Ghazavi, F, Huysentruyt, J, De Coninck, J, Kourula, S, Martens, S, Hassannia, B, Wartewig, T, Divert, T, Roelandt, R, Popper, B, Hiergeist, A, Tougaard, P, Vanden Berghe, T, Joossens, M, Berx, G, Takahashi, N, Wahida, A, Vandenabeele, P.
Executioner caspases 3 and 7 are dispensable for intestinal epithelium turnover and homeostasis at steady state
Proc Natl Acad Sci U S A 119, e2024508119, 2022. (Epub 2022 Feb 8)

Gros, M, Segura, E, Rookhuizen, DC, Baudon, B, Heurtebise-Chretien, S, Burgdorf, N, Maurin, M, Kapp, EA, Simpson, RJ, Kozik, P, Villadangos, JA, Bertrand, MJM, Burbage, M, Amigorena, S.
Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation
Cell Rep 40, 111205, 2022. (Epub 2022 Aug 16)

Martens, S, Takahashi, N, Blancke, G, Vandamme, N, Verschuere, H, Divert, T, Vuylsteke, M, Berx, G, Vandenabeele, P.
MLKL deficiency in Braf(V600E)Pten(-/-) melanoma model results in a modest delay of nevi development and reduced lymph node dissemination in male mice
Cell Death Dis 13, 347, 2022. (Epub 2022 Apr 14)

Naesens, L, Nemegeer, J, Roelens, F, Vallaeys, L, Meuwissen, M, Janssens, K, Verloo, P, Ogunjimi, B, Hemelsoet, D, Program for Undiagnosed Rare, D, Hoste, L, Roels, L, De Bruyne, M, De Baere, E, Van Dorpe, J, Dendooven, A, Sieben, A, Rice, GI, Kerre, T, et al..
Mutations in RNU7-1 Weaken Secondary RNA Structure, Induce MCP-1 and CXCL10 in CSF, and Result in Aicardi-Goutieres Syndrome with Severe End-Organ Involvement
J Clin Immunol 42, 962-974, 2022. (Epub 2022 Mar 23)

Oltean, T, Ibanez, LI, Divert, T, Ysenbaert, T, Van Eeckhoutte, H, Goossens, V, Schotsaert, M, Bracke, K, Schepens, B, Maelfait, J, Takahashi, N, Saelens, X, Vandenabeele, P.
Reduced protection of RIPK3-deficient mice against influenza by matrix protein 2 ectodomain targeted active and passive vaccination strategies
Cell Death Dis 13, 280, 2022. (Epub 2022 Mar 29)

Oltean, T, Lippens, L, Lemeire, K, De Tender, C, Vuylsteke, M, Denys, H, Vandecasteele, K, Vandenabeele, P, Adjemian, S.
Association of Cell Death Markers With Tumor Immune Cell Infiltrates After Chemo-Radiation in Cervical Cancer
Front Oncol 12, 892813, 2022. (Epub 2022 Jul 12)

Puylaert, P, Coornaert, I, Neutel, CHG, Dondelinger, Y, Delanghe, T, Bertrand, MJM, Guns, PJ, De Meyer, GRY, Martinet, W.
The Impact of RIPK1 Kinase Inhibition on Atherogenesis: A Genetic and a Pharmacological Approach
Biomedicines 10, 1016, 2022. (Epub 2022 Apr 28)

Rigauts, C, Aizawa, J, Taylor, S, Rogers, GB, Govaerts, M, Cos, P, Ostyn, L, Sims, S, Vandeplassche, E, Sze, M, Dondelinger, Y, Vereecke, L, Van Acker, H, Simpson, JL, Burr, L, Willems, A, Tunney, MM, Cigana, C, Bragonzi, A, et al..
Rothia mucilaginosa is an anti-inflammatory bacterium in the respiratory tract of patients with chronic lung disease
Eur Respir J 59, 2101293, 2022. (Epub 2021 Sep 29)

Timmermans, S, Verhoog, NJD, Van Looveren, K, Dewaele, S, Hochepied, T, Eggermont, M, Gilbert, B, Boerema-de Munck, A, Vanderhaeghen, T, Vanden Berghe, J, Garcia Gonzalez, N, Vandewalle, J, Bloch, Y, Provost, M, Savvides, SN, De Bosscher, K, Declercq, W, Rottier, RJ, Louw, A, et al..
Point mutation I634A in the glucocorticoid receptor causes embryonic lethality by reduced ligand binding
J Biol Chem 298, 101574, 2022. (Epub 2022 Jan 7)

Van Breedam, E, Nijak, A, Buyle-Huybrecht, T, Di Stefano, J, Boeren, M, Govaerts, J, Quarta, A, Swartenbroekx, T, Jacobs, EZ, Menten, B, Gijsbers, R, Delputte, P, Alaerts, M, Hassannia, B, Loeys, B, Berneman, Z, Timmermans, JP, Jorens, PG, Vanden Berghe, T, et al..
Luminescent Human iPSC-Derived Neurospheroids Enable Modeling of Neurotoxicity After Oxygen-glucose Deprivation
Neurotherapeutics 19, 550-569, 2022. (Epub 2022 Mar 14)

Van Coillie, S, Van San, E, Goetschalckx, I, Wiernicki, B, Mukhopadhyay, B, Tonnus, W, Choi, SM, Roelandt, R, Dumitrascu, C, Lamberts, L, Dams, G, Weyts, W, Huysentruyt, J, Hassannia, B, Ingold, I, Lele, S, Meyer, E, Berg, M, Seurinck, R, et al..
Targeting ferroptosis protects against experimental (multi)organ dysfunction and death
Nat Commun 13, 1046, 2022. (Epub 2022 Feb 24)

Van Hauwermeiren, F, Van Opdenbosch, N, Van Gorp, H, de Vasconcelos, N, van Loo, G, Vandenabeele, P, Kanneganti, TD, Lamkanfi, M.
Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax
Proc Natl Acad Sci U S A 119, e2116415119, 2022. (Epub 2022 Jan 11)

Verdonck, S, Nemegeer, J, Vandenabeele, P, Maelfait, J.
Viral manipulation of host cell necroptosis and pyroptosis
Trends Microbiol 30, 593-605, 2022. (Epub 2021 Dec 18)

Wiernicki, B, Maschalidi, S, Pinney, J, Adjemian, S, Vanden Berghe, T, Ravichandran, KS, Vandenabeele, P.
Cancer cells dying from ferroptosis impede dendritic cell-mediated anti-tumor immunity
Nat Commun 13, 3676, 2022. (Epub 2022 Jun 27)

Aaes, TL, Vandenabeele, P.
The intrinsic immunogenic properties of cancer cell lines, immunogenic cell death, and how these influence host antitumor immune responses
Cell Death Differ 28, 843-860, 2021. (Epub 2020 Nov 19)

Ackermann, M, Anders, HJ, Bilyy, R, Bowlin, GL, Daniel, C, De Lorenzo, R, Egeblad, M, Henneck, T, Hidalgo, A, Hoffmann, M, Hohberger, B, Kanthi, Y, Kaplan, MJ, Knight, JS, Knopf, J, Kolaczkowska, E, Kubes, P, Leppkes, M, Mahajan, A, et al..
Patients with COVID-19: in the dark-NETs of neutrophils
Cell Death Differ 28, 3125-3139, 2021. (Epub 2021 May 24)

Anderson, CJ, Medina, CB, Barron, BJ, Karvelyte, L, Aaes, TL, Lambertz, I, Perry, JSA, Mehrotra, P, Goncalves, A, Lemeire, K, Blancke, G, Andries, V, Ghazavi, F, Martens, A, van Loo, G, Vereecke, L, Vandenabeele, P, Ravichandran, KS.
Microbes exploit death-induced nutrient release by gut epithelial cells
Nature 596, 262-267, 2021. (Epub 2021 Aug 4)

Coornaert, I, Puylaert, P, Marcasolli, G, Grootaert, MOJ, Vandenabeele, P, De Meyer, GRY, Martinet, W.
Impact of myeloid RIPK1 gene deletion on atherogenesis in ApoE-deficient mice
Atherosclerosis 322, 51-60, 2021. (Epub 2021 Feb 24)

Delanghe, T, Huyghe, J, Lee, S, Priem, D, Van Coillie, S, Gilbert, B, Choi, SM, Vandenabeele, P, Degterev, A, Cuny, GD, Dondelinger, Y, Bertrand, MJM.
Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor
Cell Death Dis 12, 699, 2021. (Epub 2021 Jul 14)

de Reuver, R, Dierick, E, Wiernicki, B, Staes, K, Seys, L, De Meester, E, Muyldermans, T, Botzki, A, Lambrecht, BN, Van Nieuwerburgh, F, Vandenabeele, P, Maelfait, J.
ADAR1 interaction with Z-RNA promotes editing of endogenous double-stranded RNA and prevents MDA5-dependent immune activation
Cell Rep 36, 109500, 2021. (Epub 2021 Aug 10)

De Schutter, E, Cappe, B, Wiernicki, B, Vandenabeele, P, Riquet, FB.
Plasma membrane permeabilization following cell death: many ways to dye!
Cell Death Discov 7, 183, 2021. (Epub 2021 Jul 19)

De Schutter, E, Roelandt, R, Riquet, FB, Van Camp, G, Wullaert, A, Vandenabeele, P.
Punching Holes in Cellular Membranes: Biology and Evolution of Gasdermins
Trends Cell Biol 31, 500-513, 2021. (Epub 2021 Mar 23)

Le Naour, J, Liu, P, Zhao, L, Adjemian, S, Sztupinszki, Z, Taieb, J, Mulot, C, Silvin, A, Dutertre, CA, Ginhoux, F, et al., Vandenabeele, P, et al., Kroemer, G.
A TLR3 ligand reestablishes chemotherapeutic responses in the context of FPR1 deficiency
Cancer Discov 11, 408-423, 2021. (Epub 2020 Oct 12)

Lu, Z, Van Eeckhoutte, HP, Liu, G, Nair, PM, Jones, B, Gillis, CM, Nalkurthi, BC, Verhamme, F, Buyle-Huybrecht, T, Vandenabeele, P, Vanden Berghe, T, Brusselle, GG, Murphy, JM, Wark, PA, Bracke, KR, Fricker, M, Hansbro, PM.
Necroptosis Signalling Promotes Inflammation, Airway Remodelling and Emphysema in COPD
Am J Respir Crit Care Med 204, 667-681, 2021. (Epub 2021 Jun 16)

Martens, S, Bridelance, J, Roelandt, R, Vandenabeele, P, Takahashi, N.
MLKL in cancer: more than a necroptosis regulator
Cell Death Differ 28, 1757-1772, 2021. (Epub 2021 May 5)

Meyts, I, Bucciol, G, Quinti, I, Neven, B, Fischer, A, Seoane, E, Lopez-Granados, E, Gianelli, C, Robles-Marhuenda, A, Jeandel, PY, Paillard, C, Sankaran, VG, Demirdag, YY, et al, Bosteels, C, Lambrecht, BN, et al..
Coronavirus Disease 2019 in patients with inborn errors of immunity: an international study
J Allergy Clin Immunol 147, 520-531, 2021. (Epub 2020 Sep 24)

Oltean, T, Van San, E, Divert, T, Vanden Berghe, T, Saelens, X, Maelfait, J, Takahashi, N, Vandenabeele, P.
Viral dosing of influenza A infection reveals involvement of RIPK3 and FADD, but not MLKL
Cell Death Dis 12, 471, 2021. (Epub 2021 May 11)

Ponsioen, B, Post, JB, Buissant des Amorie, JR, Laskaris, D, van Ineveld, RL, Kersten, S, Bertotti, A, Sassi, F, Sipieter, F, Cappe, B, Mertens, S, Verlaan-Klink, I, Boj, SF, Vries, RGJ, Rehmann, H, Vandenabeele, P, Riquet, FB, Trusolino, L, Bos, JL, et al..
Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling
Nat Cell Biol 23, 377-390, 2021. (Epub 2021 Apr 1)

Sipieter, F, Cappe, B, Leray, A, De Schutter, E, Bridelance, J, Hulpiau, P, Van Camp, G, Declercq, W, Heliot, L, Vincent, P, Vandenabeele, P, Riquet, FB.
Characteristic ERK1/2 signaling dynamics distinguishes necroptosis from apoptosis
iScience 24, 103074, 2021. (Epub 2021 Sep 24)

Wahida, A, Muller, M, Hiergeist, A, Popper, B, Steiger, K, Branca, C, Tschurtschenthaler, M, Engleitner, T, Donakonda, S, De Coninck, J, Ollinger, R, Pfautsch, MK, Muller, N, Silva, M, Usluer, S, Thiele Orberg, E, Bottcher, JP, Pfarr, N, Anton, M, et al..
XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells
Sci Immunol 6, eabf7235, 2021. (Epub 2021 Nov 5)

Wehn, AC, Khalin, I, Duering, M, Hellal, F, Culmsee, C, Vandenabeele, P, Plesnila, N, Terpolilli, NA.
RIPK1 or RIPK3 deletion prevents progressive neuronal cell death and improves memory function after traumatic brain injury
Acta Neuropathol Commun 9, 138, 2021. (Epub 2021 Aug 17)

Aaes, TL, Verschuere, H, Kaczmarek, A, Heyndrickx, L, Wiernicki, B, Delrue, I, De Craene, B, Taminau, J, Delvaeye, T, Bertrand, MJM, Declercq, W, Berx, G, Krysko, DV, Adjemian, S, Vandenabeele, P.
Immunodominant AH1 Antigen-Deficient Necroptotic, but Not Apoptotic, Murine Cancer Cells Induce Antitumor Protection
J Immunol 204, 775-787, 2020. (Epub 2020 Jan 3)

Adjemian, S, Oltean, T, Martens, S, Wiernicki, B, Goossens, V, Vanden Berghe, T, Cappe, B, Ladik, M, Riquet, FB, Heyndrickx, L, Bridelance, J, Vuylsteke, M, Vandecasteele, K, Vandenabeele, P.
Ionizing radiation results in a mixture of cellular outcomes including mitotic catastrophe, senescence, methuosis, and iron-dependent cell death
Cell Death Dis 11, 1003, 2020. (Epub 2020 Nov 23)

Delanghe, T, Dondelinger, Y, Bertrand, MJM.
RIPK1 Kinase-Dependent Death: A Symphony of Phosphorylation Events
Trends Cell Biol 30, 189-200, 2020. (Epub 2020 Jan 17)

De Samber, B, Vanden Berghe, T, Meul, E, Bauters, S, Seyrich, M, Smet, J, De Paepe, B, da Silva, JC, Bohic, S, Cloetens, P, Van Coster, R, Vandenabeele, P, Vincze, L.
Nanoscopic X-ray imaging and quantification of the iron cellular architecture within single fibroblasts of Friedreich's ataxia patients
J Synchrotron Radiat 27, 185-198, 2020. (Epub 2020 Jan 1)

de Vasconcelos, NM, Van Opdenbosch, N, Van Gorp, H, Martin-Perez, R, Zecchin, A, Vandenabeele, P, Lamkanfi, M.
An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages
Cell Rep 32, 107959, 2020. (Epub 2020 Jul 28)

Devos, M, Tanghe, G, Gilbert, B, Dierick, E, Verheirstraeten, M, Nemegeer, J, de Reuver, R, Lefebvre, S, De Munck, J, Rehwinkel, J, Vandenabeele, P, Declercq, W, Maelfait, J.
Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation
J Exp Med 217, e20191913, 2020. (Epub 2020 Apr 21)

Ferrada, L, Barahona, MJ, Salazar, K, Vandenabeele, P, Nualart, F.
Vitamin C controls neuronal necroptosis under oxidative stress
Redox Biol 29, 101408, 2020. (Epub 2019 Dec 16)

Galluzzi, L, Vitale, I, Warren, S, Adjemian, S, Agostinis, P, Martinez, AB, Chan, TA, Coukos, G, Demaria, S, Deutsch, E, Draganov, D, Edelson, RL, Formenti, SC, Fucikova, J, Gabriele, L, Gaipl, US, Gameiro, SR, Garg, AD, Golden, E, et al..
Consensus guidelines for the definition, detection and interpretation of immunogenic cell death
J Immunother Cancer 8, e000337, 2020. (Epub 2020 Mar 9)

Garcia-Pupo, L, Van San, E, Delgado-Hernandez, R, Vanden Berghe, T, Vanden Berghe, W.
Emerging immune and cell death mechanisms in stroke: Saponins as therapeutic candidates
Brain Behav Immun Health 9, 100152, 2020. (Epub 2020 Oct 3)

Hassannia, B, Logie, E, Vandenabeele, P, Vanden Berghe, T, Vanden Berghe, W.
Withaferin A: from Ayurvedic folk medicine to preclinical anti-cancer drug
Biochem Pharmacol 173, 113602, 2020. (Epub 2019 Aug 9)

Laurien, L, Nagata, M, Schunke, H, Delanghe, T, Wiederstein, JL, Kumari, S, Schwarzer, R, Corona, T, Kruger, M, Bertrand, MJM, Kondylis, V, Pasparakis, M.
Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation
Nat Commun 11, 1747, 2020. (Epub 2020 Apr 8)

Maelfait, J, Liverpool, L, Rehwinkel, J.
Nucleic Acid Sensors and Programmed Cell Death
J Mol Biol 432, 552-568, 2020. (Epub 2019 Nov 28)

Martens, A, Priem, D, Hoste, E, Vetters, J, Rennen, S, Catrysse, L, Voet, S, Deelen, L, Sze, M, Vikkula, H, Slowicka, K, Hochepied, T, Iliaki, K, Wullaert, A, Janssens, S, Lamkanfi, M, Beyaert, R, Armaka, M, Bertrand, MJM, et al..
Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities
Nat Immunol 21, 381-387, 2020. (Epub 2020 Mar 16)

Martens, S, Hofmans, S, Declercq, W, Augustyns, K, Vandenabeele, P.
Inhibitors Targeting RIPK1/RIPK3: Old and New Drugs
Trends Pharmacol Sci 41, 209-224, 2020. (Epub 2020 Feb 5)

Priem, D, van Loo, G, Bertrand, MJM.
A20 and Cell Death-driven Inflammation
Trends Immunol 41, 421-435, 2020. (Epub 2020 Mar 30)

Roberti, MP, Yonekura, S, Duong, CPM, Picard, M, Ferrere, G, Tidjani Alou, M, , et al., Kourula, S, et al., Vanden Berghe, T, Ghiringhelli, F, Vandenabeele, P, Kroemer, G, Zitvogel, L.
Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer
Nat Med 26, 919-931, 2020. (Epub 2020 May 25)

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