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Van de Craen, M, Vandenabeele, P, Declercq, W, Van den brande, I, van Loo, G, Molemans, F, Schotte, P, Van Criekinge, W, Beyaert, R, Fiers, W.
Characterization of seven murine caspase family members
FEBS Lett 403, 61-69, 1997. (Epub ---)

Van de Craen, M, Van den brande, I, Declercq, W, Irmler, M, Beyaert, R, Tschopp, J, Fiers, W, Vandenabeele, P.
Cleavage of caspase family members by granzyme B: A comparative study in vitro
Eur J Immunol 27, 1296-1299, 1997. (Epub ---)

Vercammen, D, Vandenabeele, P, Beyaert, R, Declercq, W, Fiers, W.
Tumour necrosis factor-induced necrosis versus anti-Fas-induced apoptosis in L929 cells
Cytokine 9, 801-808, 1997. (Epub ---)

Wallach, D, Boldin, M, Varfolomeev, E, Beyaert, R, Vandenabeele, P, Fiers, W.
Cell death induction by receptors of the TNF family: Towards a molecular understanding
FEBS Lett 410, 96-106, 1997. (Epub ---)

Benigni, F, Faggioni, R, Sironi, M, Fantuzzi, G, Vandenabeele, P, Takahashi, N, Sacco, S, Fiers, W, Buurman, WA, Ghezzi, P.
TNF receptor p55 plays a major role in centrally mediated increases of serum IL-6 and corticosterone after intracerebroventricular injection of TNF
J Immunol 157, 5563-5568, 1996. (Epub ---)

Fiers, W, Beyaert, R, Boone, E, Cornelis, S, Declercq, W, Decoster, E, Denecker, G, Depuydt, B, De Valck, D, De Wilde, G, Goossens, V, Grooten, J, Haegeman, G, Heyninck, K, Penning, L, Plaisance, S, Vancompernolle, K, Van Criekinge, W, Vandenabeele, P, et al..
TNF-induced intracellular signaling leading to gene induction or to cytotoxicity by necrosis or by apoptosis
J Inflamm 47, 67-75, 1996. (Epub ---)

Marchant, A, Amraoui, Z, Gueydan, C, Bruyns, C, Le Moine, O, Vandenabeele, P, Fiers, W, Buurman, WA, Goldman, M.
Methylprednisolone differentially regulates interleukin-10 and tumor necrosis factor production during murine endotoxemia
Clin Exp Immunol 106, 91-96, 1996. (Epub ---)

Van Criekinge, W, Beyaert, R, Van de Craen, M, Vandenabeele, P, Schotte, P, De Valck, D, Fiers, W.
Functional characterization of the prodomain of interleukin-1b-converting enzyme
J Biol Chem 271, 27245-27248, 1996. (Epub ---)

Beyaert, R, Vanhaesebroeck, B, Declercq, W, Van Lint, J, Vandenabeele, P, Agostinis, P, Vandenheede, JR, Fiers, W.
Casein kinase-1 phosphorylates the p75 tumor necrosis factor receptor and negatively regulates tumor necrosis factor signaling for apoptosis
J Biol Chem 270, 23293-23299, 1995. (Epub ---)

Declercq, W, Vandenabeele, P, Fiers, W.
Dimerization of chimeric erythropoietin/75 kDa tumour necrosis factor (TNF) receptors transduces TNF signals: Necessity for the 75 kDa-TNF receptor transmembrane domain
Cytokine 7, 701-709, 1995. (Epub ---)

Decoster, E, Vanhaesebroeck, B, Vandenabeele, P, Grooten, J, Fiers, W.
Generation and biological characterization of membrane-bound, uncleavable murine tumor necrosis factor
J Biol Chem 270, 18473-18478, 1995. (Epub ---)

Vandenabeele, P, Declercq, W, Beyaert, R, Fiers, W.
Two tumour necrosis factor receptors: Structure and function
Trends Cell Biol 5, 392-399, 1995. (Epub ---)

Vandenabeele, P, Declercq, W, Vanhaesebroeck, B, Grooten, J, Fiers, W.
Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells
J Immunol 154, 2904-2913, 1995. (Epub ---)

Vercammen, D, Vandenabeele, P, Declercq, W, Van de Craen, M, Grooten, J, Fiers, W.
Cytotoxicity in L929 murine fibrosarcoma cells after triggering of transfected human p75 tumour necrosis factor (TNF) receptor is mediated by endogenous murine TNF
Cytokine 7, 463-470, 1995. (Epub ---)

Barbara, JAJ, Smith, WB, Gamble, JR, Van Ostade, X, Vandenabeele, P, Tavernier, J, Fiers, W, Vadas, MA, Lopez, AF.
Dissociation of TNF-a cytotoxic and proinflammatory activities by p55 receptor- and p75 receptor-selective TNF-a mutants
EMBO J 13, 843-850, 1994. (Epub ---)

Donckier, V, Abramowicz, D, Bruyns, C, Florquin, S, Vanderhaegen, M-L, Amraoui, Z, Dubois, C, Vandenabeele, P, Goldman, M.
IFN-g prevents Th2 cell-mediated pathology after neonatal injection of semiallogenic spleen cells in mice
J Immunol 153, 2361-2368, 1994. (Epub ---)

Donckier, V, Flament, V, Gérard, C, Abramowicz, D, Vandenabeele, P, Wissing, M, Delvaux, A, Fiers, W, Leo, O, Velu, T, Goldman, M.
Modulation of the release of cytokines and reduction of the shock syndrome induced by anti-CD3 monoclonal antibody in mice by interleukin-10
Transplantation 57, 1436-1439, 1994. (Epub ---)

Flamand, V, Donckier, V, Abramowicz, D, Goldman, M, Vandenabeele, P, Urbain, J, Moser, M, Leo, O.
In vivo immunosuppression induced by a weakly mitogenic antibody to mouse CD3: Evidence that induction of long-lasting in vivo unresponsiveness requires TcR signaling
Cell Immunol 157, 239-248, 1994. (Epub ---)

Marchant, A, Bruyns, C, Vandenabeele, P, Abramowicz, D, Gérard, C, Delvaux, A, Ghezzi, P, Velu, T, Goldman, M.
The protective role of interleukin-10 in endotoxin shock
Prog Clin Biol Res 388, 417-423, 1994. (Epub ---)

Marchant, A, Bruyns, C, Vandenabeele, P, Ducarme, M, Gérard, C, Delvaux, A, De Groote, D, Abramowicz, D, Velu, T, Goldman, M.
Interleukin-10 controls interferon-gamma and tumor necrosis factor production during experimental endotoxemia
Eur J Immunol 24, 1167-1171, 1994. (Epub ---)

Vandenabeele, P, Goossens, V, Beyaert, R, Declercq, W, Grooten, J, Vanhaesebroeck, B, Van de Craen, M, Vercammen, D, Depuydt, B, Denecker, G, Fiers, W.
Functional requirement of the two TNF receptors for induction of apoptosis in PC60 cells and the role of mitochondria in TNF-induced cytotoxicity
Circ Shock 44, 196-200, 1994. (Epub ---)

Van Ostade, X, Vandenabeele, P, Tavernier, J, Fiers, W.
Human tumor necrosis factor mutants with preferential binding to and activity on either the R55 or R75 receptor
Eur J Biochem 220, 771-779, 1994. (Epub ---)

Fiers, W, Beyaert, R, Brouckaert, P, Cauwels, A, Declercq, W, De Valck, D, Everaerdt, B, Goossens, V, Grooten, J, Haegeman, G, Libert, C, Schulze-Osthoff, K, Takahashi, N, Vandenabeele, P, Vanhaesebroeck, B, Van Ostade, X, Van Roy, F.
Two pathways of tumor necrosis factor signal transduction: In vitro and in vivo implications
In Tumor Necrosis Factor: Molecular and Cellular Biology and Clinical Relevance. (Fiers, W, Buurman, WA, eds.), Basel, Karger (Shugar, D, Rode, W, Borowski, E, eds.), Warszawa-Berlin, Polish Scientific Publishers PWN/Springer-Verlag, pp. 58-65, 1993. (Epub ---)

Gérard, C, Bruyns, C, Marchant, A, Abramowicz, D, Vandenabeele, P, Delvaux, A, Fiers, W, Goldman, M, Velu, T.
Interleukin 10 reduces the release of tumor necrosis factor and prevents lethality in experimental endotoxemia
J Exp Med 177, 547-550, 1993. (Epub ---)

Vandenabeele, P, Abramowicz, D, Berus, D, Van der Heyden, J, Grooten, J, Donckier, V, Hooghe-Peters, EL, Goldman, M, Fiers, W.
Increased IL-6 production and IL-6-mediated Ig secretion in murine host-vs-graft disease
J Immunol 150, 4179-4187, 1993. (Epub ---)

Van Ostade, X, Vandenabeele, P, Everaerdt, B, Loetscher, H, Gentz, R, Brockhaus, M, Lesslauer, W, Tavernier, J, Brouckaert, P, Fiers, W.
Human TNF mutants with selective activity on the p55 receptor
Nature 361, 266-269, 1993. (Epub ---)

Vandenabeele, P, Declercq, W, Vercammen, D, Van de Craen, M, Grooten, J, Loetscher, H, Brockhaus, M, Lesslauer, W, Fiers, W.
Functional characterization of the human tumor necrosis factor receptor p75 in a transfected rat/mouse T cell hybridoma
J Exp Med 176, 1015-1024, 1992. (Epub ---)

Alegre, ML, Gastaldello, K, Abramowicz, D, Kinnaert, P, Vereerstraeten, P, De Pauw, L, Vandenabeele, P, Moser, M, Leo, O, Goldman, M.
Evidence that pentoxifylline reduces anti-CD3 monoclonal antibody-induced cytokine release syndrome
Transplantation 52, 674-679, 1991. (Epub ---)

Alegre, M-L, Vandenabeele, P, Depierreux, M, Florquin, S, Deschodt-Lanckman, M, Flamand, V, Moser, M, Leo, O, Urbain, J, Fiers, W, Goldman, M.
Cytokine release syndrome induced by the 145-2C11 anti-CD3 monoclonal antibody in mice: Prevention by high doses of methylprednisolone
J Immunol 146, 1184-1191, 1991. (Epub ---)

Nortier, J, Vandenabeele, P, Noel, E, Bosseloir, Y, Goldman, M, Deschodt-Lanckman, M.
Enzymatic degradation of tumor necrosis factor by activated human neutrophils: Role of elastase
Life Sci 49, 1879-1886, 1991. (Epub ---)

Vandenabeele, P, Fiers, W.
Is amyloidogenesis during Alzheimer's disease due to an IL-1/IL-6-mediated 'acute phase response' in the brain?
Immunol Today 12, 217-219, 1991. (Epub ---)

Abramowicz, D, Vandervorst, P, Bruyns, C, Doutrelepont, JM, Vandenabeele, P, Goldman, M.
Persistence of anti-donor allohelper T cells after neonatal induction of allotolerance in mice
Eur J Immunol 20, 1647-1653, 1990. (Epub ---)

Alegre, M, Depierreux, M, Florquin, S, Najdovski, T, Vandenabeele, P, Abramowicz, D, Leo, O, Deschodt-Lanckman, M, Goldman, M.
Acute toxicity of anti-CD3 monoclonal antibody in mice: A model for OKT3 first dose reactions
Transplant Proc 22, 1920-1921, 1990. (Epub ---)

Alegre, M, Vandenabeele, P, Flamand, V, Moser, M, Leo, O, Abramowicz, D, Urbain, J, Fiers, W, Goldman, M.
Hypothermia and hypoglycemia induced by anti-CD3 monoclonal antibody in mice: Role of tumor necrosis factor
Eur J Immunol 20, 707-710, 1990. (Epub ---)

Goldman, M, Vandenabeele, P, Moulart, J, Amraoui, Z, Abramowicz, D, Nortier, J, Vanherweghem, JL, Fiers, W.
Intraperitoneal secretion of interleukin-6 during continuous ambulatory peritoneal dialysis
Nephron 56, 277-280, 1990. (Epub ---)

Vandenabeele, P, Declercq, W, Libert, C, Fiers, W.
Development of a simple, sensitive and specific bioassay for interleukin-1 based on the proliferation of RPMI 1788 cells. Comparison with other bioassays for IL-1
J Immunol Methods 135, 25-32, 1990. (Epub ---)

Vandenabeele, P, Grooten, J, Fiers, W.
IL-4 acts synergistically on the IL-2 response of an autoreactive T-cell clone; synergism correlates with increased intracellular IL-2, but not with a modified IL-2 receptor expression
Cell Immunol 130, 79-91, 1990. (Epub ---)

Vandenabeele, P, Guisez, Y, Declercq, W, Bauw, G, Vandekerckhove, J, Fiers, W.
Response of murine cell lines to an IL-1/IL-2-induced factor in a rat/mouse T hybridoma (PC60): Differential induction of cytokines by human IL-1a and IL-1b and partial amino acid sequence of rat GM-CSF
Lymphokine Res 9, 381-389, 1990. (Epub ---)

Fiers, W, Brouckaert, P, Content, J, Contreras, R, Everaerdt, B, Guisez, Y, Libert, C, Spriggs, D, Takahashi, N, Tison, B, Vandenabeele, P, Van Snick, J.
Interleukin-6: Biological function and regulation of the gene expression in vitro and in vivo
In Advances in Immunopharmacology. (Hadden, JW, Spreafico, F, Yamamura, Y, Austen, KF, Dukor, P, Masek, K, eds.), Vol. 4, Oxford, Pergamon Press, pp. 185-190, 1989. (Epub ---)

Vandenabeele, P, Jayaram, B, Devos, R, Shaw, A, Fiers, W.
Interleukin 1a acts as an autocrine growth factor for RPMI 1788, an Epstein-Barr virus-transformed human B cell line
Eur J Immunol 18, 1027-1031, 1988. (Epub ---)

Vink, A, Vandenabeele, P, Uyttenhove, C, Cayphas, S, Van Snick, J.
Plasmacytoma growth factor activity of murine granulocyte-macrophage colony-stimulating factor
J Immunol 141, 1996-1999, 1988. (Epub ---)

Fiers, W, Beyaert, R, Brouckaert, P, Everaerdt, B, Haegeman, G, Suffys, P, Tavernier, J, Vandenabeele, P, Vanhaesebroeck, B, Van Ostade, X, Van Roy, F.
Gene cloning and structure-function relationship of cytokines such as TNF and interleukins
Immunol Lett 16, 219-226, 1987. (Epub ---)

Mueller, W, Vandenabeele, P.
A T cell clone which responds to interleukin 2 but not to interleukin 4
Eur J Immunol 17, 579-580, 1987. (Epub ---)

Poupart, P, Vandenabeele, P, Cayphas, S, Van Snick, J, Haegeman, G, Kruys, V, Fiers, W, Content, J.
B cell growth modulating and differentiating activity of recombinant human 26-kd protein (BSF-2, HuIFN-b2, HPGF)
EMBO J 6, 1219-1224, 1987. (Epub ---)

Devos, R, Jayaram, B, Vandenabeele, P, Fiers, W.
Recombinant interleukin 2 induces immunoglobulin secretion in Staphylococcus aureus Cowan strain I activated human B-cells
Immunol Lett 11, 101-105, 1985. (Epub ---)

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