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Seo, J, Seong, D, Nam, YW, Hwang, CH, Lee, SR, Lee, CS, Jin, Y, Lee, HW, Oh, DB, Vandenabeele, P, Song, J.
Beclin 1 functions as a negative modulator of MLKL oligomerisation by integrating into the necrosome complex
Cell Death Differ 27, 3065-3081, 2020. (Epub 2020 May 26)

Seong, D, Jeong, M, Seo, J, Lee, JY, Hwang, CH, Shin, HC, Shin, JY, Nam, YW, Jo, JY, Lee, H, Kim, HJ, Kim, HR, Oh, JH, Ha, SJ, Kim, SJ, Roe, JS, Kim, W, et al., Vandenabeele, P , et al..
Identification of MYC as an antinecroptotic protein that stifles RIPK1-RIPK3 complex formation
Proc Natl Acad Sci U S A 117, 19982-19993, 2020. (Epub 2020 Aug 04)

Simpson, J, Loh, Z, Ullah, MA, Lynch, JP, Werder, RB, Collinson, N, Zhang, V, Dondelinger, Y, Bertrand, MJM, Everard, ML, Blyth, CC, Hartel, G, Van Oosterhout, AJ, Gough, PJ, Bertin, J, Upham, JW, Spann, KM, Phipps, S.
RSV Infection Promotes Necroptosis and HMGB1 Release by Airway Epithelial Cells
Am J Respir Crit Care Med 201, 1358-1371, 2020. (Epub 2020 Feb 27)

Sprooten, J, De Wijngaert, P, Vanmeerbeerk, I, Martin, S, Vangheluwe, P, Schlenner, S, Krysko, DV, Parys, JB, Bultynck, G, Vandenabeele, P, Garg, AD.
Necroptosis in Immuno-Oncology and Cancer Immunotherapy
Cells 9, 1823, 2020. (Epub 2020 Aug 01)

Teufelberger, AR, Van Nevel, S, Hulpiau, P, Nordengrun, M, Savvides, SN, De Graeve, S, Akula, S, Holtappels, G, De Ruyck, N, Declercq, W, Vandenabeele, P, Hellman, L, Broker, BM, Krysko, DV, Bachert, C, Krysko, O.
Mouse Strain-Dependent Difference Toward the Staphylococcus aureus Allergen Serine Protease-Like Protein D Reveals a Novel Regulator of IL-33
Front Immunol 11, 582044, 2020. (Epub 2020 Sep 25)

Thyssen, JP, Jakasa, I, Riethmuller, C, Schon, MP, Braun, A, Haftek, M, Fallon, PG, Wroblewski, J, Jakubowski, H, Eckhart, L, Declercq, W, Koppes, S, Engebretsen, KA, Bonefeld, C, Irvine, AD, Keita-Alassane, S, Simon, M, Kawasaki, H, Kubo, A, et al..
Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice
J Invest Dermatol 140, 615-623, 2020. (Epub 2019 Aug 31)

Tougaard, P, Martinsen, LO, Lutzhoft, DO, Jensen, HE, Flethoj, M, Vandenabeele, P, Pedersen, AE, Skov, S, Hansen, AK, Hansen, CHF.
TL1A regulates adipose-resident innate lymphoid immune responses and enables diet-induced obesity in mice
Int J Obes (Lond) 44, 1062-1074, 2020. (Epub 2020 Jan 30)

Van Coillie, S, Wiernicki, B, Xu, J.
Molecular and Cellular Functions of CTLA-4
Adv Exp Med Biol 1248, 7-32, 2020. (Epub 2020 Mar 18)

Verboom, L, Martens, A, Priem, D, Hoste, E, Sze, M, Vikkula, HK, Van Hove, L, Voet, S, Roels, J, Maelfait, J, Bongiovanni, L, de Bruin, A, Scott, CL, Saeys, Y, Pasparakis, M, Bertrand, MJM, van Loo, G.
OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis
Cell Rep 30, 2237-2247, 2020. (Epub 2020 Feb 18)

Wiernicki, B, Dubois, H, Tyurina, YY, Hassannia, B, Bayir, H, Kagan, VE, Vandenabeele, P, Wullaert, A, Vanden Berghe, T.
Excessive phospholipid peroxidation distinguishes ferroptosis from other cell death modes including pyroptosis
Cell Death Dis 11, 922, 2020. (Epub 2020 Oct 27)

Beltran, S, Nassif, M, Vicencio, E, Arcos, J, Labrador, L, Cortes, BI, Cortez, C, Bergmann, CA, Espinoza, S, Hernandez, MF, Matamala, JM, Bargsted, L, Matus, S, Rojas-Rivera, D, Bertrand, MJM, Medinas, DB, Hetz, C, Manque, PA, Woehlbier, U.
Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis
Mol Neurodegener 14, 14, 2019. (Epub 2019 Mar 27)

Boeltz, S, Amini, P, Anders, HJ, Andrade, F, Bilyy, R, Chatfield, S, Cichon, I, Clancy, DM, Desai, J, et al., Maueroder, C, et al. , Vanden Berghe, T, Vandenabeele, P, Hahn, J, Hidalgo, A, Hoffmann, MH, Kaplan, MJ, Knight, JS, Kolaczkowska, E, Kubes, P, et al..
To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps
Cell Death Differ 26, 395-408, 2019. (Epub 2019 Jan 8)

Delvaeye, T, De Smet, MAJ, Verwaerde, S, Decrock, E, Czekaj, A, Vandenbroucke, RE, Lemeire, K, Goncalves, A, Declercq, W, Vandenabeele, P, Krysko, DV, Leybaert, L.
Blocking connexin43 hemichannels protects mice against tumour necrosis factor-induced inflammatory shock
Sci Rep 9, 16623, 2019. (Epub 2019 Nov 12)

Devos, M, Mogilenko, DA, Fleury, S, Gilbert, B, Becquart, C, Quemener, S, Dehondt, H, Tougaard, P, Staels, B, Bachert, C, Vandenabeele, P, Van Loo, G, Staumont-Salle, D, Declercq, W, Dombrowicz, D.
Keratinocyte expression of A20/TNFAIP3 controls skin inflammation associated with atopic dermatitis and psoriasis
J Invest Dermatol 139, 135-145, 2019. (Epub 2018 Aug 14)

Dondelinger, Y, Delanghe, T, Priem, D, Wynosky-Dolfi, MA, Sorobetea, D, Rojas-Rivera, D, Giansanti, P, Roelandt, R, Gropengiesser, J, Ruckdeschel, K, Savvides, SN, Heck, AJR, Vandenabeele, P, Brodsky, IE, Bertrand, MJM.
Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation
Nat Commun 10, 1729, 2019. (Epub 2019 Apr 15)

Elvas, F, Vanden Berghe, T, Adriaenssens, Y, Vandenabeele, P, Augustyns, K, Staelens, S, Stroobants, S, Van der Veken, P, Wyffels, L.
Caspase-3 probes for PET imaging of apoptotic tumor response to anticancer therapy
Org Biomol Chem 17, 4801-4824, 2019. (Epub 2019 Apr 29)

Hassannia, B, Vandenabeele, P, Vanden Berghe, T.
Targeting Ferroptosis to Iron Out Cancer
Cancer Cell 35, 830-849, 2019. (Epub 2019 May 16)

Hoste, E, Maueroder, C, van Hove, L, Catrysse, L, Vikkula, HK, Sze, M, Maes, B, Karjosukarso, D, Martens, L, Goncalves, A, Parthoens, E, Roelandt, R, Declercq, W, Fuentes, I, Palisson, F, Gonzalez, S, Salas-Alanis, JC, Boon, L, Huebener, P, et al..
Epithelial HMGB1 Delays Skin Wound Healing and Drives Tumor Initiation by Priming Neutrophils for NET Formation
Cell Rep 29, 2689-2701, 2019. (Epub 2019 Nov 26)

Kavcic, N, Pegan, K, Vandenabeele, P, Turk, B.
Comparative study of the differential cell death protecting effect of various ROS scavengers
Biol Chem 400, 149-160, 2019. (Epub 2018 Sep 19)

Konieczny, P, Lichawska-Cieslar, A, Kwiecinska, P, Cichy, J, Pietrzycka, R, Szukala, W, Declercq, W, Devos, M, Paziewska, A, Rumienczyk, I, Kulecka, M, Mikula, M, Fu, M, Borowczyk, J, Santamaria-Babi, LF, Jura, J.
Keratinocyte-specific ablation of Mcpip1 impairs skin integrity and promotes local and systemic inflammation
J Mol Med (Berl) 97, 1669-1684, 2019. (Epub 2019 Nov 30)

Napoletano, F, Baron, O, Vandenabeele, P, Mollereau, B, Fanto, M.
Intersections between Regulated Cell Death and Autophagy
Trends Cell Biol 29, 323-338, 2019. (Epub 2019 Jan 18)

Priem, D, Devos, M, Druwe, S, Martens, A, Slowicka, K, Ting, AT, Pasparakis, M, Declercq, W, Vandenabeele, P, van Loo, G, Bertrand, MJM.
A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms
Cell Death Dis 10, 692, 2019. (Epub 2019 Sep 18)

Sabel, R, Fronza, AS, Carrenho, LZB, Maes, A, Barros, ML, Pollo, LAE, Biavatti, MW, D'Herde, K, Vandenabeele, P, Kreuger.
Anti-inflammatory activity of the sesquiterpene lactone diacethylpiptocarphol in dextransulfate sodium-induced colitis in mice
J Ethnopharmacol 245, 112186, 2019. (Epub 2019 Aug 28)

Tanc, M, Cleenewerck, M, Kurdi, A, Roelandt, R, Declercq, W, De Meyer, G, Augustyns, K, Martinet, W, Van der Veken, P.
Synthesis and evaluation of novel benzotropolones as Atg4B inhibiting autophagy blockers
Bioorg Chem 87, 163-168, 2019. (Epub 2019 Mar 13)

Tang, D, Kang, R, Vanden Berghe, T, Vandenabeele, P, Kroemer, G.
The molecular machinery of regulated cell death
Cell Res 29, 347-364, 2019. (Epub 2019 Apr 6)

Vanden Berghe, T, Hoste, E.
Paving the way for precision medicine v2.0 in intensive care by profiling necroinflammation in biofluids
Cell Death Differ 26, 8398, 2019. (Epub 2018 Sep 10)

Van Hoecke, L, Raes, L, Stremersch, S, Brans, T, Fraire, JC, Roelandt, R, Declercq, W, Vandenabeele, P, Raemdonck, K, Braeckmans, K, Saelens, X.
Delivery of Mixed-Lineage Kinase Domain-Like Protein by Vapor Nanobubble Photoporation Induces Necroptotic-Like Cell Death in Tumor Cells
International Journal of Molecular Sciences 20, E4254, 2019. (Epub 2019 Aug 30)

Vetters, J, van Helden, MJ, Wahlen, S, Tavernier, SJ, Martens, A, Fayazpour, F, Vergote, K, Vanheerswynghels, M, Deswarte, K, Van Moorleghem, J, De Prijck, S, Takahashi, N, Vandenabeele, P, Boon, L, van Loo, G, Vivier, E, Lambrecht, BN, Janssens, S.
The ubiquitin-editing enzyme A20 controls NK cell homeostasis through regulation of mTOR activity and TNF
J Exp Med 216, 2010-2023, 2019. (Epub 2019 Jul 11)

Webb, LV, Barbarulo, A, Huysentruyt, J, Vanden Berghe, T, Takahashi, N, Ley, S, Vandenabeele, P, Seddon, B.
Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-kappaB
Immunity 50, 348-361, 2019. (Epub 2019 Jan 23)

Zachariassen, LF, Hansen, AK, Krych, L, Nielsen, DS, Holm, TL, Tougaard, P, Hansen, CHF.
Cesarean section increases sensitivity to oxazolone-induced colitis in C57BL/6 mice
Mucosal Immunol 12, 1348-1357, 2019. (Epub 2019 Sep 25)

Annibaldi, A, Wicky John, S, Vanden Berghe, T, Swatek, KN, Ruan, J, Liccardi, G, Bianchi, K, Elliott, PR, Choi, SM, Van Coillie, S, Bertin, J, Wu, H, Komander, D, Vandenabeele, P, Silke, J, Meier, P.
Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2
Mol Cell 69, 566-580, 2018. (Epub 2018 Feb 15)

Ballegeer, M, Van Looveren, K, Timmermans, S, Eggermont, M, Vandevyver, S, Thery, F, Dendoncker, K, Souffriau, J, Vandewalle, J, Van Wyngene, L, De Rycke, R, Takahashi, N, Vandenabeele, P, Tuckermann, J, Reichardt, HM, Impens, F, Beyaert, R, De Bosscher, K, Vandenbroucke, RE, et al..
Glucocorticoid receptor dimers control intestinal STAT1 and TNF-induced inflammation in mice
J Clin Invest 128, 3265-3279, 2018. (Epub 2018 May 10)

Borghi, A, Haegman, M, Fischer, R, Carpentier, I, Bertrand, MJM, Libert, C, Afonina, IS, Beyaert, R.
The E3 ubiquitin ligases HOIP and cIAP1 are recruited to the TNFR2 signaling complex and mediate TNFR2-induced canonical NF-kappaB signaling
Biochem Pharmacol 153, 292-298, 2018. (Epub 2018 Jan 26)

Deckers, J, Bougarne, N, Mylka, V, Desmet, S, Luypaert, A, Devos, M, Tanghe, G, Van Moorleghem, J, Vanheerswynghels, M, De Cauwer, L, Thommis, J, Vuylsteke, M, Tavernier, J, Lambrecht, B, Hammad, H, De Bosscher, K.
Co-activation of GR and PPARgamma in murine skin prevents worsening of atopic march
J Invest Dermatol 138, 1360-1370, 2018. (Epub 2017 Dec 27)

Delvaeye, T, Vandenabeele, P, Bultynck, G, Leybaert, L, Krysko, DV.
Therapeutic Targeting of Connexin Channels: New Views and Challenges
Trends Mol Med 24, 1036-1053, 2018. (Epub 2018 Nov 10)

Delvaeye, T, Wyffels, L, Deleye, S, Lemeire, K, Goncalves, A, Decrock, E, Staelens, S, Leybaert, L, Vandenabeele, P, Krysko, DV.
Noninvasive whole-body imaging of phosphatidylethanolamine as a cell death marker using (99m)Tc-duramycin during TNF-induced SIRS
J Nucl Med 59, 1140-1145, 2018. (Epub 2018 Feb 1)

De Samber, B, Meul, E, Laforce, B, De Paepe, B, Smet, J, De Bruyne, M, De Rycke, R, Bohic, S, Cloetens, P, Van Coster, R, Vandenabeele, P, Vanden Berghe, T.
Nanoscopic X-ray fluorescence imaging and quantification of intracellular key-elements in cryofrozen Friedreich's ataxia fibroblasts
PLoS One 13, e0190495, 2018. (Epub 2018 Jan 17)

Devisscher, L, Van Coillie, S, Hofmans, S, Van Rompaey, D, Goossens, K, Meul, E, Maes, L, De Winter, H, Van Der Veken, P, Vandenabeele, P, Vanden Berghe, T, Augustyns, K.
Discovery of Novel, Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy
J Med Chem 61, 10126-10140, 2018. (Epub 2018 Nov 21)

D'Hondt, S, Guillemyn, B, Syx, D, Symoens, S, De Rycke, R, Vanhoutte, L, Toussaint, W, Lambrecht, BN, De Paepe, A, Keene, DR, Ishikawa, Y, Bachinger, HP, Janssens, S, Bertrand, MJM, Malfait, F.
Type III collagen affects dermal and vascular collagen fibrillogenesis and tissue integrity in a mutant Col3a1 transgenic mouse model
Matrix Biol 70, 72-83, 2018. (Epub 2018 Mar 15)

Dondelinger, Y, Delanghe, T, Bertrand, MJM.
MK2 puts an additional brake on RIPK1 cytotoxic potential
Cell Death Differ 25, 457-459, 2018. (Epub 2018 Jan 9)

Drebert, Z, De Vlieghere, E, Bridelance, J, De Wever, O, De Bosscher, K, Bracke, M, Beck, IM.
Glucocorticoids indirectly decrease colon cancer cell proliferation and invasion via effects on cancer-associated fibroblasts
Exp Cell Res 362, 332-342, 2018. (Epub 2018 Jan 15)

Estornes, Y, Dondelinger, Y, Weber, K, Bruggeman, I, Peall, A, MacFarlane, M, Lebecque, S, Vandenabeele, P, Bertrand, MJM.
N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis
Cell Death Dis 9, 494, 2018. (Epub 2018 May 2)

Galluzzi, L, Vitale, I, Aaronson, SA, Abrams, JM, Adam, D, Agostinis, P, Alnemri, ES, et al., Bertrand, MJM, et al., Vanden Berghe, T, Vandenabeele, P, et al., Kroemer,G.
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
Cell Death Differ 25, 486-541, 2018. (Epub 2018 Jan 23)

Geric, I, Tyurina, YY, Krysko, O, Krysko, DV, De Schryver, E, Kagan, VE, Van Veldhoven, PP, Baes, M, Verheijden, S.
Lipid homeostasis and inflammatory activation are disturbed in classically activated macrophages with peroxisomal beta-oxidation deficiency
Immunology 153, 342-356, 2018. (Epub 2017 Sep 22)

Hassannia, B, Wiernicki, B, Ingold, I, Qu, F, Van Herck, S, Tyurina, YY, Bayir, H, Abhari, BA, Angeli, JPF, Choi, SM, Meul, E, Heyninck, K, et al., Lahtela-Kakkonen, M, Van Camp, G, Krysko, DV, Ekert, PG, Fulda, S,De Geest, B.G., Vanden Berghe, W., Vandenabeele, P., Vanden Berghe, T.
Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
J Clin Invest 128, 3341-3355, 2018. (Epub 2018 Jun 25)

Hofmans, S, Devisscher, L, Martens, S, Van Rompaey, D, Goossens, K, Divert, T, Nerinckx, W, Takahashi, N, De Winter, H, Van der Veken, P, Goossens, V, Vandenabeele, P, Augustyns, K.
Tozasertib analogues as inhibitors of necroptotic cell death
J Med Chem 61, 1895-1920, 2018. (Epub 2018 Feb 13)

Krysko, DV, Ravichandran, KS, Vandenabeele, P.
Macrophages regulate the clearance of living cells by calreticulin
Nat Commun 9, 4644, 2018. (Epub 2018 Nov 7)

Martens, S, Goossens, V, Devisscher, L, Hofmans, S, Claeys, P, Vuylsteke, M, Takahashi, N, Augustyns, K, Vandenabeele, P.
RIPK1-dependent cell death: a novel target of the Aurora kinase inhibitor Tozasertib (VX-680)
Cell Death Dis 9, 211, 2018. (Epub 2018 Feb 12)

Priem, D, Dondelinger, Y, Bertrand, MJM.
Monitoring RIPK1 Phosphorylation in the TNFR1 Signaling Complex
Methods Mol Biol 1857, 171-179, 2018. (Epub 2018 Aug 23)

Saavedra, PHV, Huang, L, Ghazavi, F, Kourula, S, Vanden Berghe, T, Takahashi, N, Vandenabeele, P, Lamkanfi, M.
Apoptosis of intestinal epithelial cells restricts Clostridium difficile infection in a model of pseudomembranous colitis
Nat Commun 9, 4846, 2018. (Epub 2018 Nov 19)

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