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Kurdi, A, Cleenewerck, M, Vangestel, C, Lyssens, S, Declercq, W, Timmermans, JP, Stroobants, S, Augustyns, K, De Meyer, GRY, Van Der Veken, P, Martinet, W.
ATG4B inhibitors with a benzotropolone core structure block autophagy and augment efficiency of chemotherapy in mice
Biochem Pharmacol 138, 150-162, 2017. (Epub 2017 Jun 19)

Latil, M, Nassar, D, Beck, B, Boumahdi, S, Wang, L, Brisebarre, A, Dubois, C, Nkusi, E, Lenglez, S, Checinska, A, Vercauteren Drubbel, A, Devos, M, Declercq, W, Yi, R, Blanpain, C.
Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
Cell Stem Cell 20, 191-204, 2017. (Epub 2016 Nov 16)

Le Cann, F, Delehouze, C, Penna-Leverrier, S, Filliol, A, Comte, A, Delalande, O, Desban, N, Baratte, B, Gallais, I, Piquet-Pellorce, C, Faurez, F, Bonnet, M, Mettey, Y, Goekjian, P, Samson, M, Vandenabeele, P, Bach, S, Dimanche-Boitrel, MT.
Sibiriline, a new small chemical inhibitor of Receptor-Interacting Protein Kinase 1, prevents immune-dependent hepatitis
FEBS J 284, 3050-3068, 2017. (Epub 2017 Jul 17)

Linkermann, A, Stockwell, BR, Vanden Berghe, T.
Heavy Metal Suicide
Am J Physiol Renal Physiol 313, F959-F960, 2017. (Epub 2017 May 31)

Martens, S, Jeong, M, Tonnus, W, Feldmann, F, Hofmans, S, Goossens, V, Takahashi, N, Brasen, JH, Lee, EW, Van der Veken, P, Joossens, J, Augustyns, K, Fulda, S, Linkermann, A, Song, J, Vandenabeele, P.
Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury
Cell Death Dis 8, e2904, 2017. (Epub 2017 Jun 29)

Rojas-Rivera, D, Delvaeye, T, Roelandt, R, Nerinckx, W, Augustyns, K, Vandenabeele, P, Bertrand, MJM.
When PERK inhibitors turn out to be new potent RIPK1 inhibitors: critical issues on the specificity and use of GSK2606414 and GSK2656157
Cell Death Differ 24, 1100-1110, 2017. (Epub 2017 Apr 28)

Vandenabeele, P, Riquet, F, Cappe, B.
Necroptosis: (Last) Message in a Bubble
Immunity 47, 1-3, 2017. (Epub 2017 Jul 18)

Vanden Berghe, T, Kaiser, WJ.
RIPK1 prevents aberrant ZBP1-initiated necroptosis
Oncotarget 8, 1-2, 2017. (Epub 2017 Jan 3)

Zakharova, VV, Pletjushkina, OY, Galkin, II, Zinovkin, RA, Chernyak, BV, Krysko, DV, Bachert, C, Krysko, O, Skulachev, VP, Popova, EN.
Low concentration of uncouplers of oxidative phosphorylation decreases the TNF-induced endothelial permeability and lethality in mice
Biochim Biophys Acta 1863, 968-977, 2017. (Epub 2017 Jan 26)

Aaes, TL, Kaczmarek, A, Delvaeye, T, De Craene, B, De Koker, S, Heyndrickx, L, Delrue, I, Taminau, J, Wiernicki, B, De Groote, P, Garg, AD, Leybaert, L, Grooten, J, Bertrand, MJ, Agostinis, P, Berx, G, Declercq, W, Vandenabeele, P, Krysko, DV.
Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity
Cell Rep 15, 274-287, 2016. (Epub 2016 Mar 30)

Aguileta, MA, Rojas-Rivera, D, Goossens, V, Estornes, Y, Van Isterdael, G, Vandenabeele, P, Bertrand, MJ.
A siRNA screen reveals the prosurvival effect of protein kinase A activation in conditions of unresolved endoplasmic reticulum stress
Cell Death Differ 23, 1670-1680, 2016. (Epub 2016 Jun 24)

Al-Lamki, RS, Wang, J, Yang, J, Burrows, N, Maxwell, PH, Eisen, T, Warren, AY, Vanharanta, S, Pacey, S, Vandenabeele, P, Pober, JS, Bradley, JR.
Tumor necrosis factor receptor 2-signaling in CD133-expressing cells in renal clear cell carcinoma
Oncotarget 7, 24111-24124, 2016. (Epub 2016 Mar 16)

Bol, M, Wang, N, De Bock, M, Wacquier, B, Decrock, E, Gadicherla, A, Decaluwe, K, Vanheel, B, van Rijen, HV, Krysko, DV, Bultynck, G, Dupont, G, Van de Voorde, J, Leybaert, L.
At the cross-point of connexins, calcium and ATP: blocking hemichannels inhibits vasoconstriction of rat small mesenteric arteries
Cardiovasc Res 113, 195-206, 2016. (Epub 2016 Sep 27)

Canli, O, Alankus, YB, Grootjans, S, Vegi, N, Hultner, L, Hoppe, PS, Schroeder, T, Vandenabeele, P, Bornkamm, GW, Greten, FR.
Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors
Blood 127, 139-148, 2016. (Epub 2015 Oct 13)

Cleenewerck, M, Grootaert, MO, Gladysz, R, Adriaenssens, Y, Roelandt, R, Joossens, J, Lambeir, AM, De Meyer, GR, Declercq, W, Augustyns, K, Martinet, W, Van der Veken, P.
Inhibitor screening and enzymatic activity determination for autophagy target Atg4B using a gel electrophoresis-based assay
Eur J Med Chem 123, 631-638, 2016. (Epub 2016 Jul 31)

Conrad, M, Angeli, JP, Vandenabeele, P, Stockwell, BR.
Regulated necrosis: disease relevance and therapeutic opportunities
Nat Rev Drug Discov 15, 348-366, 2016. (Epub 2016 Jan 18)

De Groote, P, Grootjans, S, Lippens, S, Eichperger, C, Leurs, K, Kahr, I, Tanghe, G, Bruggeman, I, De Schamphelaire, W, Urwyler, C, Vandenabeele, P, Haustraete, J, Declercq, W.
Generation of a new Gateway-compatible inducible lentiviral vector platform allowing easy derivation of co-transduced cells
Biotechniques 60, 252-259, 2016. (Epub 2016 May 1)

Dondelinger, Y, Darding, M, Bertrand, MJ, Walczak, H.
Poly-ubiquitination in TNFR1-mediated necroptosis
Cell Mol Life Sci 73, 21652176, 2016. (Epub 2016 Apr 11)

Dondelinger, Y, Hulpiau, P, Saeys, Y, Bertrand, MJ, Vandenabeele, P.
An evolutionary perspective on the necroptotic pathway
Trends Cell Biol 26, 721-732, 2016. (Epub 2016 Jun 28)

Dondelinger, Y, Vandenabeele, P, Bertrand, MJ.
Regulation of RIPK1's cell death function by phosphorylation
Cell Cycle 15, 5-6, 2016. (Epub 2015 Oct 30)

Filliol, A, Piquet-Pellorce, C, Le Seyec, J, Farooq, M, Genet, V, Lucas-Clerc, C, Bertin, J, Gough, PJ, Dimanche-Boitrel, MT, Vandenabeele, P, Bertrand, MJ, Samson, M.
RIPK1 protects from TNF-alpha-mediated liver damage during hepatitis
Cell Death Dis 7, e2462, 2016. (Epub 2016 Nov 10)

Garg, AD, Krysko, DV, Vandenabeele, P, Agostinis, P.
Extracellular ATP and P2X7 receptor exert context-specific immunogenic effects after immunogenic cancer cell death
Cell Death Dis 7, e2097, 2016. (Epub 2016 Feb 18)

Grootaert, MO, Schrijvers, DM, Van Spaendonk, H, Breynaert, A, Hermans, N, Van Hoof, VO, Takahashi, N, Vandenabeele, P, Kim, SH, De Meyer, GR, Martinet, W.
NecroX-7 reduces necrotic core formation in atherosclerotic plaques of Apoe knockout mice
Atherosclerosis 252, 166-174, 2016. (Epub 2016 Sep)

Grootjans, S, Hassannia, B, Delrue, I, Goossens, V, Wiernicki, B, Dondelinger, Y, Bertrand, MJ, Krysko, DV, Vuylsteke, M, Vandenabeele, P, Vanden Berghe, T.
A real-time fluorometric method for the simultaneous detection of cell death type and rate
Nat Protoc 11, 1444-1454, 2016. (Epub 2016 Jul 14)

Gunther, C, He, GW, Kremer, AE, Murphy, JM, Petrie, EJ, Amann, K, Vandenabeele, P, Linkermann, A, Poremba, C, Schleicher, U, Dewitz, C, Krautwald, S, Neurath, MF, Becker, C, Wirtz, S.
The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis
J Clin Invest 126, 4346-4360, 2016. (Epub 2016 Oct 18)

Hofmans, S, Vanden Berghe, T, Devisscher, L, Hassannia, B, Lyssens, S, Joossens, J, Van der Veken, P, Vandenabeele, P, Augustyns, K.
Novel ferroptosis inhibitors with improved potency and ADME properties
J Med Chem 59, 2041-2053, 2016. (Epub 2015 Dec 22)

Klionsky, DJ, Abdelmohsen, K, Abe, A, Abedin, MJ, Abeliovich, H, Acevedo Arozena, A, Adachi, H, Adams, CM, Adams, PD, Adeli, K, et.al. Vandenabeele, P, et al. Zorzano, A, Zughaier, SM.
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy 12, 1-222, 2016. (Epub 2016 Jan 2)

Laghmani, K, Beck, BB, Yang, SS, Seaayfan, E, Wenzel, A, Reusch, B, Vitzthum, H, Priem, D, Demaretz, S, Bergmann, K, Duin, LK, Gobel, H, Mache, C, Thiele, H, Bartram, MP, Dombret, C, Altmuller, J, Nurnberg, P, Benzing, T, Bertrand MJ et al..
Polyhydramnios, Transient Antenatal Bartter's Syndrome, and MAGED2 Mutations
N Engl J Med 374, 1853-1863, 2016. (Epub 2016 May 12)

Laukens, D, Brinkman, BM, Raes, J, De Vos, M, Vandenabeele, P.
Heterogeneity of the gut microbiome in mice: guidelines for optimizing experimental design
FEMS Microbiol Rev 40, 117-132, 2016. (Epub 2015 Aug 31)

Lee, CS, Penberthy, KK, Wheeler, KM, Juncadella, IJ, Vandenabeele, P, Lysiak, JJ, Ravichandran, KS.
Boosting Apoptotic Cell Clearance by Colonic Epithelial Cells Attenuates Inflammation In Vivo
Immunity 44, 807-820, 2016. (Epub 2016 Mar 28)

Moreno-Gonzalez, G, Vandenabeele, P, Krysko, DV.
Necroptosis: a Novel Cell Death Modality and its Potential Relevance for Critical Care Medicine
Am J Respir Crit Care Med 194, 415-428, 2016. (Epub 2016 Jun 10)

Panayotova-Dimitrova, D, Declercq, W.
Martin Leverkus, MD (1965-2016)
J Invest Dermatol 136, 891-892, 2016. (Epub 2016 May)

Pouwels, SD, Zijlstra, GJ, van der Toorn, M, Hesse, L, Gras, R, Ten Hacken, NH, Krysko, DV, Vandenabeele, P, de Vries, M, van Oosterhout, AJ, Heijink, IH, Nawijn, MC.
Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice
Am J Physiol Lung Cell Mol Physiol 310, 1377-1386, 2016. (Epub 2015 Dec 30)

Seo, J, Lee, EW, Sung, H, Seong, D, Dondelinger, Y, Shin, J, Jeong, M, Lee, HK, Kim, JH, Han, SY, Lee, C, Seong, JK, Vandenabeele, P, Song, J.
CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3
Nat Cell Biol 18, 291-302, 2016. (Epub 2016 Feb 22)

Ting, AT, Bertrand, MJ.
More to Life than NF-kappaB in TNFR1 Signaling
Trends Immunol 37, 535-545, 2016. (Epub 2016 Jul 13)

Tortola, L, Nitsch, R, Bertrand, MJ, Kogler, M, Redouane, Y, Kozieradzki, I, Uribesalgo, I, Fennell, LM, Daugaard, M, Klug, H, Wirnsberger, G, Wimmer, R, Perlot, T, Sarao, R, Rao, S, Hanada, T, Takahashi, N, Kernbauer, E, Vandenabeele, P, et al..
The Tumor Suppressor Hace1 Is a Critical Regulator of TNFR1-Mediated Cell Fate
Cell Rep 15, 1481-1492, 2016. (Epub 2016 May 17)

Vandenabeele, P, Vandecasteele, K, Bachert, C, Krysko, O, Krysko, DV.
Immunogenic Apoptotic Cell Death and Anticancer Immunity
Adv Exp Med Biol 930, 133-149, 2016. (Epub 2016 Aug 25)

Vanden Berghe, T, Hassannia, B, Vandenabeele, P.
An outline of necrosome triggers
Cell Mol Life Sci 73, 2137-2152, 2016. (Epub 2016 Apr 6)

Babu, D, Leclercq, G, Goossens, V, Remijsen, Q, Vandenabeele, P, Motterlini, R, Lefebvre, RA.
Antioxidant potential of CORM-A1 and resveratrol during TNF-alpha/cycloheximide-induced oxidative stress and apoptosis in murine intestinal epithelial MODE-K cells
Toxicol Appl Pharmacol , in press, 2015. (Epub 2015 Jul 14)

Babu, D, Leclercq, G, Goossens, V, Vanden Berghe, T, Van Hamme, E, Vandenabeele, P, Lefebvre, RA.
Mitochondria and NADPH oxidases are the major sources of TNF-alpha/cycloheximide-induced oxidative stress in murine intestinal epithelial MODE-K cells
Cell Signal 27, 1141-1158, 2015. (Epub 2015 Feb 26)

Boutaffala, L, Bertrand, MJ, Remouchamps, C, Seleznik, G, Reisinger, F, Janas, M, Benezech, C, Fernandes, MT, Marchetti, S, Mair, F, Ganeff, C, Hupalowska, A, Ricci, JE, Becher, B, Piette, J, Knolle, P, Caamano, J, Vandenabeele, P, Heikenwalder, M, Dejardin, E.
NIK promotes tissue destruction independently of the alternative NF-kappaB pathway through TNFR1/RIP1-induced apoptosis
Cell Death Differ 22, 2020-2033, 2015. (Epub 2015 Jun 5)

Dondelinger, Y, Jouan-Lanhouet, S, Divert, T, Theatre, E, Bertin, J, Gough, PJ, Giansanti, P, Heck, AJ, Dejardin, E, Vandenabeele, P, Bertrand, MJ.
NF-kappaB-Independent Role of IKKalpha/IKKbeta in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling
Mol Cell 60, 63-76, 2015. (Epub 2015 Oct 1)

Garg, AD, Elsen, S, Krysko, DV, Vandenabeele, P, de Witte, P, Agostinis, P.
Resistance to anticancer vaccination effect is controlled by a cancer cell-autonomous phenotype that disrupts immunogenic phagocytic removal
Oncotarget 6, 26841 - 26860, 2015. (Epub 2015 Jul 23)

Garg, AD, Galluzzi, L, Apetoh, L, Baert, T, Birge, RB, Bravo-San Pedro, JM, Breckpot, K, Brough, D, Chaurio, R, Cirone, M, Coosemans, A, Coulie, PG, De Ruysscher, D, Dini, L,et al. Krysko, D, Vandenabeele, P, de Witte, P, Dudek-Peric, AM, Faggioni, A, Fucikova, J, Gaipl, US, et al..
Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death
Front Immunol 6, 88, 2015. (Epub 2015 Nov 20)

Heard, KN, Bertrand, MJ, Barker, PA.
cIAP2 supports viability of mice lacking cIAP1 and XIAP
EMBO J 34, 2393-2395, 2015. (Epub 2015 Oct 1)

Lyrio, EC, Campos-Souza, IC, Correa, C, Lechuga, G, Vericimo, M, Castro, HC, Bourguignon, SC, Faria, SC, Ratcliffe, N, Declercq, W, Santos, DO.
Interaction of Mycobacterium leprae with the HaCaT human keratinocyte cell line: New frontiers in the cellular immunology of leprosy
Exp Dermatol 24, 536-542, 2015. (Epub 2015 Apr 1)

Pasparakis, M, Vandenabeele, P.
Necroptosis and its role in inflammation
Nature 517, 311-320, 2015. (Epub 2015 Jan 15)

Saveljeva, S, Mc Laughlin, SL, Vandenabeele, P, Samali, A, Bertrand, MJ.
Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells
Cell Death Dis 6, e1587, 2015. (Epub 2015 Jan 8)

Schulz, S, Chisholm, KM, Zhao, H, Kalish, F, Yang, Y, Wong, RJ, Stevenson, DK.
Heme oxygenase-1 confers protection and alters T cell populations in a mouse model of neonatal intestinal inflammation
Pediatr Res 77, 640-648, 2015. (Epub 2015 Feb 9)

Sipieter, F, Cappe, B, Gonzalez Pisfil, M, Spriet, C, Bodart, JF, Cailliau-Maggio, K, Vandenabeele, P, Heliot, L, Riquet, FB.
Novel Reporter for Faithful Monitoring of ERK2 Dynamics in Living Cells and Model Organisms
PLoS One 10, e0140924, 2015. (Epub 2015 Oct 30)

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