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Scott, CL, T'Jonck, W, Martens, L, Todorov, H, Sichien, D, Soen, B, Bonnardel, J, De Prijck, S, Vandamme, N, Cannoodt, R, Saelens, W, Vanneste, B, Toussaint, W, De Bleser, P, Takahashi, N, Vandenabeele, P, et al., Lambrecht, BN, De Baetselier, P, Milling, SWF, Van Ginderachter, JA, Malissen, B, Berx, G, Beschin, A, Saeys, Y, Guilliams, M.
The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages
Immunity 49, 312-325, 2018. (Epub 2018 Jul 31)

Tanghe, G, Urwyler-Rosselet, C, De Groote, P, Dejardin, E, De Bock, PJ, Gevaert, K, Vandenabeele, P, Declercq, W.
RIPK4 activity in keratinocytes is controlled by the SCF(beta-TrCP) ubiquitin ligase to maintain cortical actin organization
Cell Mol Life Sci 75, 2827-2841, 2018. (Epub 2018 Feb 12)

Teufelberger, AR, Nordengrun, M, Braun, H, Maes, T, De Grove, K, Holtappels, G, O'Brien, C, Provoost, S, Hammad, H, Goncalves, A, Beyaert, R, Declercq, W, Vandenabeele, P, Krysko, DV, Broker, BM, Bachert, C, Krysko, O.
The IL-33/ST2 axis is crucial in type 2 airway responses induced by Staphylococcus aureus-derived serine protease-like protein D.
J Allergy Clin Immunol 141, 549-559, 2018. (Epub 2017 May 19)

Urwyler-Rosselet, C, Tanghe, G, Leurs, K, Gilbert, B, De Rycke, R, De Bruyne, M, Lippens, S, Bartunkova, S, De Groote, P, Niessen, C, Haftek, M, Vandenabeele, P, Declercq, W.
Keratinocyte-specific ablation of RIPK4 allows epidermal cornification but impairs skin barrier formation
J Invest Dermatol 138, 1268-1278, 2018. (Epub 2018 Jan 6)

Vandenabeele, P, Declercq, W, Roelandt, R, Vanden Berghe, T.
MLKL Reveals Its Friendly Face: A Role in Nerve Regeneration
Mol Cell 72, 397-399, 2018. (Epub 2018 Nov 1)

Van Hoecke, L, Van Lint, S, Roose, K, Van Parys, A, Vandenabeele, P, Grooten, J, Tavernier, J, De Koker, S, Saelens, X.
Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes
Nat Commun 9, 3417, 2018. (Epub 2018 Aug 24)

Weber, K, Roelandt, R, Bruggeman, I, Estornes, Y, Vandenabeele, P.
Nuclear RIPK3 and MLKL contribute to cytosolic necrosome formation and necroptosis
Commun Biol 1, 6, 2018. (Epub 2018 Jan 22)

Breyne, K, Steenbrugge, J, Demeyere, K, Vanden Berghe, T, Meyer, E.
Preconditioning with Lipopolysaccharide or Lipoteichoic Acid Protects against Staphylococcus aureus Mammary Infection in Mice
Front Immunol 8, 833, 2017. (Epub 2017 Jul 24)

Bridelance, J, Drebert, Z, De Wever, O, Bracke, M, Beck, IM.
When Neighbors Talk: Colon Cancer Cell Invasion and Tumor Microenvironment Myofibroblasts
Curr Drug Targets 18, 964-982, 2017. (Epub 2017)

De Beule, N, Menu, E, Bertrand, MJ, Favreau, M, De Bruyne, E, Maes, K, De Veirman, K, Radwanska, M, Samali, A, Magez, S, Vanderkerken, K, De Trez, C.
Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cells
Oncotarget 8, 52016-52025, 2017. (Epub 2017 May 24)

Decrock, E, Hoorelbeke, D, Ramadan, R, Delvaeye, T, De Bock, M, Wang, N, Krysko, DV, Baatout, S, Bultynck, G, Aerts, A, Vinken, M, Leybaert, L.
Calcium, oxidative stress and connexin channels, a harmonious orchestra directing the response to radiotherapy treatment?
Biochim Biophys Acta 1864, 1099-1120, 2017. (Epub 2017 Feb 11)

Delehouze, C, Leverrier-Penna, S, Le Cann, F, Comte, A, Jacquard-Fevai, M, Delalande, O, Desban, N, Baratte, B, Gallais, I, Faurez, F, Bonnet, MC, Hauteville, M, Goekjian, PG, Thuillier, R, Favreau, F, Vandenabeele, P, Hauet, T, Dimanche-Boitrel, MT, Bach, S.
6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury
Sci Rep 7, 12931, 2017. (Epub 2017 Oct 10)

Demeautis, C, Sipieter, F, Roul, J, Chapuis, C, Padilla-Parra, S, Riquet, FB, Tramier, M.
Multiplexing PKA and ERK1&2 kinases FRET biosensors in living cells using single excitation wavelength dual colour FLIM
Sci Rep 7, 41026, 2017. (Epub 2017 Jan 20)

Devos, M, Gilbert, B, Denecker, G, Leurs, K, Mc Guire, C, Lemeire, K, Hochepied, T, Vuylsteke, M, Lambert, J, Van Den Broecke, C, Libbrecht, L, Haigh, J, Berx, G, Lippens, S, Vandenabeele, P, Declercq, W.
Elevated DeltaNp63alpha levels facilitate epidermal and biliary oncogenic transformation
J Invest Dermatol 137, 494-505, 2017. (Epub 2016 Oct 7)

Dondelinger, Y, Delanghe, T, Rojas-Rivera, D, Priem, D, Delvaeye, T, Bruggeman, I, Van Herreweghe, F, Vandenabeele, P, Bertrand, MJM.
MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death
Nat Cell Biol 19, 1237-1247, 2017. (Epub 2017 Sep 18)

Fearnhead, HO, Vandenabeele, P, Vanden Berghe, T.
How do we fit ferroptosis in the family of regulated cell death?
Cell Death Differ 24, 1991-1998, 2017. (Epub 2017 Oct 6)

Feldmann, F, Schenk, B, Martens, S, Vandenabeele, P, Fulda, S.
Sorafenib inhibits therapeutic induction of necroptosis in acute leukemia cells
Oncotarget 8, 68208-68220, 2017. (Epub 2017 Aug 4)

Filliol, A, Farooq, M, Piquet-Pellorce, C, Genet, V, Dimanche-Boitrel, MT, Vandenabeele, P, Bertrand, MJM, Samson, M, Le Seyec, J.
RIPK1 protects hepatocytes from death in Fas-induced hepatitis
Sci Rep 7, 9205, 2017. (Epub 2017 Aug 23)

Filliol, A, Piquet-Pellorce, C, Raguenes-Nicol, C, Dion, S, Farooq, M, Lucas-Clerc, C, Vandenabeele, P, Bertrand, MJ, Le Seyec, J, Samson, M.
RIPK1 protects hepatocytes from Kupffer cells-mediated TNF-induced apoptosis in mouse models of PAMP-induced hepatitis
J Hepatol 66, 1205-1213, 2017. (Epub 2017 Jan 11)

Gadicherla, AK, Wang, N, Bulic, M, Agullo-Pascual, E, Lissoni, A, De Smet, M, Delmar, M, Bultynck, G, Krysko, DV, Camara, A, Schluter, KD, Schulz, R, Kwok, WM, Leybaert, L.
Mitochondrial Cx43 hemichannels contribute to mitochondrial calcium entry and cell death in the heart
Basic Res Cardiol 112, 27, 2017. (Epub 2017 May)

Grootjans, S, Vanden Berghe, T, Vandenabeele, P.
Initiation and execution mechanisms of necroptosis: an overview
Cell Death Differ 24, 1184-1195, 2017. (Epub 2017 May 12)

Hariton, WVJ, Galichet, A, Vanden Berghe, T, Overmiller, AM, Mahoney, MG, Declercq, W, Muller, EJ.
Feasibility study for clinical application of caspase-3 inhibitors in Pemphigus vulgaris
Exp Dermatol 26, 1274-1277, 2017. (Epub 2017 Nov 3)

Jeong, M, Lee, EW, Seong, D, Seo, J, Kim, JH, Grootjans, S, Kim, SY, Vandenabeele, P, Song, J.
USP8 suppresses death receptor-mediated apoptosis by enhancing FLIPL stability
Oncogene 36, 458-470, 2017. (Epub 2016 Jun 20)

Kip, E, Naze, F, Suin, V, Vanden Berghe, T, Francart, A, Lamoral, S, Vandenabeele, P, Beyaert, R, Van Gucht, S, Kalai, M.
Impact of caspase-1/11, -3, -7, or IL-1beta/IL-18 deficiency on rabies virus-induced macrophage cell death and onset of disease
Cell Death Discov 3, 17012, 2017. (Epub 2017 Mar 6)

Kourula, S, Ang, J, Zhao, H, Kalish, F, Vandenabeele, P, Sylvester, KG, Wong, RJ, Stevenson, DK.
Heme Oxygenase Activity and Heme Binding in a Neonatal Mouse Model
Neonatology 112, 376-383, 2017. (Epub 2017 Sep 20)

Krysko, O, Aaes, TL, Kagan, VE, D'Herde, K, Bachert, C, Leybaert, L, Vandenabeele, P, Krysko, DV.
Necroptotic cell death in anti-cancer therapy
Immunol Rev 280, 207-219, 2017. (Epub 2017 Oct 13)

Kurdi, A, Cleenewerck, M, Vangestel, C, Lyssens, S, Declercq, W, Timmermans, JP, Stroobants, S, Augustyns, K, De Meyer, GRY, Van Der Veken, P, Martinet, W.
ATG4B inhibitors with a benzotropolone core structure block autophagy and augment efficiency of chemotherapy in mice
Biochem Pharmacol 138, 150-162, 2017. (Epub 2017 Jun 19)

Latil, M, Nassar, D, Beck, B, Boumahdi, S, Wang, L, Brisebarre, A, Dubois, C, Nkusi, E, Lenglez, S, Checinska, A, Vercauteren Drubbel, A, Devos, M, Declercq, W, Yi, R, Blanpain, C.
Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
Cell Stem Cell 20, 191-204, 2017. (Epub 2016 Nov 16)

Le Cann, F, Delehouze, C, Penna-Leverrier, S, Filliol, A, Comte, A, Delalande, O, Desban, N, Baratte, B, Gallais, I, Piquet-Pellorce, C, Faurez, F, Bonnet, M, Mettey, Y, Goekjian, P, Samson, M, Vandenabeele, P, Bach, S, Dimanche-Boitrel, MT.
Sibiriline, a new small chemical inhibitor of Receptor-Interacting Protein Kinase 1, prevents immune-dependent hepatitis
FEBS J 284, 3050-3068, 2017. (Epub 2017 Jul 17)

Linkermann, A, Stockwell, BR, Vanden Berghe, T.
Heavy Metal Suicide
Am J Physiol Renal Physiol 313, F959-F960, 2017. (Epub 2017 May 31)

Martens, S, Jeong, M, Tonnus, W, Feldmann, F, Hofmans, S, Goossens, V, Takahashi, N, Brasen, JH, Lee, EW, Van der Veken, P, Joossens, J, Augustyns, K, Fulda, S, Linkermann, A, Song, J, Vandenabeele, P.
Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury
Cell Death Dis 8, e2904, 2017. (Epub 2017 Jun 29)

Rojas-Rivera, D, Delvaeye, T, Roelandt, R, Nerinckx, W, Augustyns, K, Vandenabeele, P, Bertrand, MJM.
When PERK inhibitors turn out to be new potent RIPK1 inhibitors: critical issues on the specificity and use of GSK2606414 and GSK2656157
Cell Death Differ 24, 1100-1110, 2017. (Epub 2017 Apr 28)

Vandenabeele, P, Riquet, F, Cappe, B.
Necroptosis: (Last) Message in a Bubble
Immunity 47, 1-3, 2017. (Epub 2017 Jul 18)

Vanden Berghe, T, Kaiser, WJ.
RIPK1 prevents aberrant ZBP1-initiated necroptosis
Oncotarget 8, 1-2, 2017. (Epub 2017 Jan 3)

Zakharova, VV, Pletjushkina, OY, Galkin, II, Zinovkin, RA, Chernyak, BV, Krysko, DV, Bachert, C, Krysko, O, Skulachev, VP, Popova, EN.
Low concentration of uncouplers of oxidative phosphorylation decreases the TNF-induced endothelial permeability and lethality in mice
Biochim Biophys Acta 1863, 968-977, 2017. (Epub 2017 Jan 26)

Aaes, TL, Kaczmarek, A, Delvaeye, T, De Craene, B, De Koker, S, Heyndrickx, L, Delrue, I, Taminau, J, Wiernicki, B, De Groote, P, Garg, AD, Leybaert, L, Grooten, J, Bertrand, MJ, Agostinis, P, Berx, G, Declercq, W, Vandenabeele, P, Krysko, DV.
Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity
Cell Rep 15, 274-287, 2016. (Epub 2016 Mar 30)

Aguileta, MA, Rojas-Rivera, D, Goossens, V, Estornes, Y, Van Isterdael, G, Vandenabeele, P, Bertrand, MJ.
A siRNA screen reveals the prosurvival effect of protein kinase A activation in conditions of unresolved endoplasmic reticulum stress
Cell Death Differ 23, 1670-1680, 2016. (Epub 2016 Jun 24)

Al-Lamki, RS, Wang, J, Yang, J, Burrows, N, Maxwell, PH, Eisen, T, Warren, AY, Vanharanta, S, Pacey, S, Vandenabeele, P, Pober, JS, Bradley, JR.
Tumor necrosis factor receptor 2-signaling in CD133-expressing cells in renal clear cell carcinoma
Oncotarget 7, 24111-24124, 2016. (Epub 2016 Mar 16)

Bol, M, Wang, N, De Bock, M, Wacquier, B, Decrock, E, Gadicherla, A, Decaluwe, K, Vanheel, B, van Rijen, HV, Krysko, DV, Bultynck, G, Dupont, G, Van de Voorde, J, Leybaert, L.
At the cross-point of connexins, calcium and ATP: blocking hemichannels inhibits vasoconstriction of rat small mesenteric arteries
Cardiovasc Res 113, 195-206, 2016. (Epub 2016 Sep 27)

Canli, O, Alankus, YB, Grootjans, S, Vegi, N, Hultner, L, Hoppe, PS, Schroeder, T, Vandenabeele, P, Bornkamm, GW, Greten, FR.
Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors
Blood 127, 139-148, 2016. (Epub 2015 Oct 13)

Cleenewerck, M, Grootaert, MO, Gladysz, R, Adriaenssens, Y, Roelandt, R, Joossens, J, Lambeir, AM, De Meyer, GR, Declercq, W, Augustyns, K, Martinet, W, Van der Veken, P.
Inhibitor screening and enzymatic activity determination for autophagy target Atg4B using a gel electrophoresis-based assay
Eur J Med Chem 123, 631-638, 2016. (Epub 2016 Jul 31)

Conrad, M, Angeli, JP, Vandenabeele, P, Stockwell, BR.
Regulated necrosis: disease relevance and therapeutic opportunities
Nat Rev Drug Discov 15, 348-366, 2016. (Epub 2016 Jan 18)

De Groote, P, Grootjans, S, Lippens, S, Eichperger, C, Leurs, K, Kahr, I, Tanghe, G, Bruggeman, I, De Schamphelaire, W, Urwyler, C, Vandenabeele, P, Haustraete, J, Declercq, W.
Generation of a new Gateway-compatible inducible lentiviral vector platform allowing easy derivation of co-transduced cells
Biotechniques 60, 252-259, 2016. (Epub 2016 May 1)

Dondelinger, Y, Darding, M, Bertrand, MJ, Walczak, H.
Poly-ubiquitination in TNFR1-mediated necroptosis
Cell Mol Life Sci 73, 21652176, 2016. (Epub 2016 Apr 11)

Dondelinger, Y, Hulpiau, P, Saeys, Y, Bertrand, MJ, Vandenabeele, P.
An evolutionary perspective on the necroptotic pathway
Trends Cell Biol 26, 721-732, 2016. (Epub 2016 Jun 28)

Dondelinger, Y, Vandenabeele, P, Bertrand, MJ.
Regulation of RIPK1's cell death function by phosphorylation
Cell Cycle 15, 5-6, 2016. (Epub 2015 Oct 30)

Filliol, A, Piquet-Pellorce, C, Le Seyec, J, Farooq, M, Genet, V, Lucas-Clerc, C, Bertin, J, Gough, PJ, Dimanche-Boitrel, MT, Vandenabeele, P, Bertrand, MJ, Samson, M.
RIPK1 protects from TNF-alpha-mediated liver damage during hepatitis
Cell Death Dis 7, e2462, 2016. (Epub 2016 Nov 10)

Garg, AD, Krysko, DV, Vandenabeele, P, Agostinis, P.
Extracellular ATP and P2X7 receptor exert context-specific immunogenic effects after immunogenic cancer cell death
Cell Death Dis 7, e2097, 2016. (Epub 2016 Feb 18)

Grootaert, MO, Schrijvers, DM, Van Spaendonk, H, Breynaert, A, Hermans, N, Van Hoof, VO, Takahashi, N, Vandenabeele, P, Kim, SH, De Meyer, GR, Martinet, W.
NecroX-7 reduces necrotic core formation in atherosclerotic plaques of Apoe knockout mice
Atherosclerosis 252, 166-174, 2016. (Epub 2016 Sep)

Grootjans, S, Hassannia, B, Delrue, I, Goossens, V, Wiernicki, B, Dondelinger, Y, Bertrand, MJ, Krysko, DV, Vuylsteke, M, Vandenabeele, P, Vanden Berghe, T.
A real-time fluorometric method for the simultaneous detection of cell death type and rate
Nat Protoc 11, 1444-1454, 2016. (Epub 2016 Jul 14)

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