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Al-Lamki, RS, Wang, J, Vandenabeele, P, Bradley, JA, Thiru, S, Luo, D, Min, W, Pober, JS, Bradley, JR.
TNFR1- and TNFR2-mediated signaling pathways in human kidney are cell type-specific and differentially contribute to renal injury
FASEB J 19, 1637-1645, 2005. (Epub ---)

Brouckaert, G, Kalai, M, Saelens, X, Vandenabeele, P.
Apoptotic pathways and their regulation
In Apoptotic pathways as targets for novel therapies in cancer and other diseases (Los, M, Gibson, SB, eds.), New York, Springer, pp. 1-29, 2005. (Epub ---)

Cornelis, S, Bruynooghe, Y, van Loo, G, Saelens, X, Vandenabeele, P, Beyaert, R.
Apoptosis of hematopoietic cells induced by growth factor withdrawal is associated with caspase-9 mediated cleavage of Raf-1
Oncogene 24, 1552-1562, 2005. (Epub ---)

Depuydt, B, van Loo, G, Vandenabeele, P, Declercq, W.
Induction of apoptosis by TNF receptor 2 in a T-cell hybridoma is FADD dependent and blocked by caspase-8 inhibitors
J Cell Sci 118, 497-504, 2005. (Epub 2005 Jan 18)

Fischer, H, Rossiter, H, Ghannadan, M, Jaeger, K, Barresi, C, Declercq, W, Tschachler, E, Eckhart, L.
Caspase-14 but not caspase-3 is processed during the development of fetal mouse epidermis
Differentiation 73, 406-413, 2005. (Epub ---)

Koenig, U, Sommergruber, W, Lippens, S.
Aberrant expression of caspase-14 in epithelial tumors
Biochem Biophys Res Commun 335, 309-313, 2005. (Epub ---)

Kroemer, G, El-Deiry, WS, Golstein, P, Peter, ME, Vaux, D, Vandenabeele, P, Zhivotovsky, B, Blagosklonny, MV, Malorni, W, Knight, RA, Piacentini, M, Nagata, S, Melino, G.
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death
Cell Death Differ 12, 1463-1467, 2005. (Epub ---)

Krysko, DV, Leybaert, L, Vandenabeele, P, D'Herde, K.
Gap junctions and the propagation of cell survival and cell death signals
Apoptosis 10, 459-469, 2005. (Epub ---)

Lamkanfi, M, D'Hondt, K, Vande Walle, L, van Gurp, M, Denecker, G, Demeulemeester, J, Kalai, M, Declercq, W, Saelens, X, Vandenabeele, P.
A novel caspase-2 complex containing TRAF2 and RIP1
J Biol Chem 280, 6923-6932, 2005. (Epub 2004 Dec 8)

Lippens, S, Denecker, G, Ovaere, P, Vandenabeele, P, Declercq, W.
Death penalty for keratinocytes: apoptosis versus cornification
Cell Death Differ 12, 1497-1508, 2005. (Epub ---)

Liu, J, Zhao, MQ, Xu, L, Ramana, CV, Declercq, W, Vandenabeele, P, Enelow, RI.
Requirement for TNF-R2 in alveolar chemokine expression depends upon the form of the ligand
Am J Respir Cell Mol Biol 33, 463-469, 2005. (Epub 2005 Aug 4)

Saelens, X, Festjens, N, Parthoens, E, Vanoverberghe, I, Kalai, M, Van Kuppeveld, F, Vandenabeele, P.
Protein synthesis persists during necrotic cell death
J Cell Biol 168, 545-551, 2005. (Epub 2005 Feb 7)

Vandenabeele, P, Orrenius, S, Zhivotovsky, B.
Serine proteases and calpains fulfill important supporting roles in the apoptotic tragedy of the cellular opera
Cell Death Differ 12, 1219-1224, 2005. (Epub ---)

Vanden Berghe, T, Festjens, N, Kalai, M, Saelens, X, Vandenabeele, P.
Fas induced necrosis
In Fas Signaling. (Wajant, H, ed.), Georgetown, Eurekah Landes Bioscience, 52-68, 2005. (Epub ---)

Vande Walle, L, Festjens, N, Saelens, X, Vandenabeele, P.
Mitochondria: Breathe or die
In Apoptosis. (Scovassi, AI, ed.), Kerala, India, Research Signpost, pp.77-105, 2005. (Epub ---)

Brouckaert, G, Kalai, M, Krysko, D, Saelens, X, Vercammen, D, Ndlovu, M, Haegeman, G, D'Herde, K, Vandenabeele, P.
Phagocytosis of necrotic cells by macrophages is phosphatidylserine-dependent and does not induce inflammatory cytokine production
Mol Biol Cell 15, 1089-1100, 2004. (Epub 2003 Dec 10)

Festjens, N, van Gurp, M, van Loo, G, Saelens, X, Vandenabeele, P.
Bcl-2 family members as sentinels of cellular integrity and role of mitochondrial intermembrane space proteins in apoptotic cell death
Acta Haematol 111, 7-27, 2004. (Epub ---)

Fischer, H, Stichenwirth, M, Dockal, M, Ghannadan, M, Buchberger, M, Bach, J, Kapetanopoulos, A, Declercq, W, Tschachler, E, Eckhart, L.
Stratum corneum-derived caspase-14 is catalytically active
FEBS Lett 577, 446-450, 2004. (Epub ---)

Lamkanfi, M, Denecker, G, Kalai, M, D'hondt, K, Meeus, A, Declercq, W, Vandenabeele, P, Saelens, X.
INCA: a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation
J Biol Chem 279, 51729-51738, 2004. (Epub 2004 Dec 10)

Lamkanfi, M, Kalai, M, Saelens, X, Declercq, W, Vandenabeele, P.
Caspase-1 activates NF-kB independent of its enzymatic activity
J Biol Chem 279, 24785–24793, 2004. (Epub 2004 Mar 23)

Lamkanfi, M, Kalai, M, Vandenabeele, P.
Caspase-12: an overview
Cell Death Differ 11, 365-368, 2004. (Epub ---)

Lippens, S, Kockx, M, Denecker, G, Knaapen, M, Verheyen, A, Christiaen, R, Tschachler, E, Vandenabeele, P, Declercq, W.
Vitamin D3 induces caspase-14 expression in psoriatic lesions and enhances caspase-14 processing in organotypic skin cultures
Am J Pathol 165, 833-841, 2004. (Epub ---)

Saelens, X, Festjens, N, Vande Walle, L, van Gurp, M, van Loo, G, Vandenabeele, P.
Toxic proteins released from mitochondria in cell death
Oncogene 23, 2861-2874, 2004. (Epub ---)

Saelens, X, van Loo, G, Gevaert, K, Vandekerckhove, J, Vandenabeele, P.
The use of proteomics to identify and characterize cell death proteins
In: When Cells Die II: A Comprehensive Evaluation of Apoptosis and Programmed Cell Death. (Lockshin, RA, Zakeri, Z, eds.), 2nd ed. Hoboken, Wiley , pp. 405-435, 2004. (Epub ---)

Schotte, P, Denecker, G, Van Den Broeke, A, Vandenabeele, P, Cornelis, G, Beyaert, R.
Targeting Rac1 by the Yersinia effector protein YopE inhibits caspase-1 mediated maturation and release of interleukin-1beta (IL-1beta )
J Biol Chem 279, 25134-25142, 2004. (Epub 2004 Apr 1)

Vanden Berghe, T, Denecker, G, Brouckaert, G, Krysko, D, D'Herde, K, Vandenabeele, P.
More Than One Way to Die: Methods to Determine TNF-Induced Apoptosis and Necrosis
Methods Mol Med 98, 101-126, 2004. (Epub ---)

Vanden Berghe, T, van Loo, G, Saelens, X, van Gurp, M, Brouckaert, G, Kalai, M, Declercq, W, Vandenabeele, P.
Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD
J Biol Chem 279, 7925-7933, 2004. (Epub 2003 Dec 10)

Vanderheyde, N, Vandenabeele, P, Goldman, M, Willems, F.
Distinct mechanisms are involved in tumoristatic and tumoricidal activities of monocyte-derived dendritic cells
Immunol Lett 91, 99-101, 2004. (Epub ---)

Van Laethem, A, Van Kelst, S, Lippens, S, Declercq, W, Vandenabeele, P, Janssens, S, Vandenheede, JR, Garmyn, M, Agostinis, P.
Activation of p38 MAPK is required for Bax translocation to mitochondria, cytochrome c release and apoptosis induced by UVB irradiation in human keratinocytes
FASEB J 18, 1946-1948, 2004. (Epub 2004 Sep 23)

Vántus, T, Vertommen, D, Saelens, X, Rykx, A, De Kimpe, L, Vancauwenbergh, S, Mikhalap, S, Waelkens, E, Kéri, G, Seufferlein, T, Vandenabeele, P, Rider, M, Vandenheede, J, Van Lint, J.
Doxorubicin-induced activation of protein kinase D1 through caspase-mediated proteolytic cleavage: Identification of two cleavage sites by microsequencing
Cell Signal 16, 703-709, 2004. (Epub ---)

Assefa, Z, Garmyn, M, Vantieghem, A, Declercq, W, Vandenabeele, P, Vandenheede, JR, Agostinis, P.
Ultraviolet B radiation-induced apoptosis in human keratinocytes: Cytosolic activation of procaspase-8 and the role of Bcl-2
FEBS Lett 540, 125-132, 2003. (Epub ---)

Frame, MJ, Tate, R, Adams, DR, Morgan, KM, Houslay, MD, Vandenabeele, P, Pyne, NJ.
Interaction of caspase-3 with the cyclic GMP binding cyclic GMP specific phosphodiesterase (PDE5a1)
Eur J Biochem 270, 962-970, 2003. (Epub ---)

Fratelli, M, Minto, M, Crespi, A, Erba, E, Vandenabeele, P, Del Soldato, P, Ghezzi, P.
Inhibition of nuclear factor-kB by a nitro-derivative of flurbiprofen: A possible mechanism for antiinflammatory and antiproliferative effect
Antioxid Redox Signal 5, 229-235, 2003. (Epub ---)

Hunter, I, Cobban, HJ, Vandenabeele, P, MacEwan, DJ, Nixon, GF.
Tumor necrosis factor-alpha-induced activation of RhoA in airway smooth muscle cells: Role in the Ca2+ sensitization of myosin light chain20 phosphorylation
Mol Pharmacol 63, 714-721, 2003. (Epub ---)

Jupp, OJ, Vandenabeele, P, MacEwan, DJ.
Distinct regulation of cytosolic phospholipase A2 phosphorylation, translocation, proteolysis and activation by tumour necrosis factor-receptor subtypes
Biochem J 374, 453-461, 2003. (Epub ---)

Kahns, S, Kalai, M, Jakobsen, LD, Clark, BFC, Vandenabeele, P, Jensen, PH.
Caspase-1 and caspase-8 cleave and inactivate cellular parkin
J Biol Chem 278, 23376-23380, 2003. (Epub 2003 Apr 11)

Kalai, M, Lamkanfi, M, Denecker, G, Boogmans, M, Lippens, S, Meeus, A, Declercq, W, Vandenabeele, P.
Regulation of the expression and processing of caspase-12
J Cell Biol 162, 457-467, 2003. (Epub 2003 Jul 28)

Krysko, DV, Brouckaert, G, Kalai, M, Vandenabeele, P, D'Herde, K.
Mechanisms of internalization of apoptotic and necrotic L929 cells by a macrophage cell line studied by electron microscopy
J Morphol 258, 336-345, 2003. (Epub 2003 Sep 30)

Lamkanfi, M, Declercq, W, Depuydt, B, Kalai, M, Saelens, X, Vandenabeele, P.
The caspase family
In Caspases-Their Role in Cell Death and Cell Survival. (Los, M & Walczak, H, eds.), Georgetown/New York, Landes Bioscience/Kluwer Academic-Plenum Publishers, pp. 1-40, 2003. (Epub ---)

Lauwaet, T, Oliveira, MJ, Callewaert, B, De Bruyne, G, Saelens, X, Ankri, S, Vandenabeele, P, Mirelman, D, Mareel, M, Leroy, A.
Proteolysis of enteric cell villin by Entamoeba histolytica cysteine proteinases
J Biol Chem 278, 22650-22656, 2003. (Epub 2003 Apr 10)

Lippens, S, VandenBroecke, C, Van Damme, E, Tschachler, E, Vandenabeele, P, Declercq, W.
Caspase-14 is expressed in the epidermis, the choroid plexus, the retinal pigment epithelium and thymic Hassall's bodies
Cell Death Differ 10, 257-259, 2003. (Epub ---)

Littlejohn, AF, Tucker, SJ, Mohamed, AAA, McKay, S, Helms, MJ, Vandenabeele, P, MacEwan, DJ.
Modulation by caspases of tumor necrosis factor-stimulated c-Jun N-terminal kinase activation but not nuclear factor-kB signaling
Biochem Pharmacol 65, 91-99, 2003. (Epub ---)

Malmegrim de Farias, KCR, Saelens, X, Pruijn, GJM, Vandenabeele, P, van Venrooij, WJ.
Caspase-mediated cleavage of the U snRNP-associated Sm-F protein during apoptosis
Cell Death Differ 10, 570-579, 2003. (Epub ---)

Rozman-Pungercar, J, Kopitar-Jerala, N, Bogyo, M, Turk, D, Vasiljeva, O, Stefe, I, Vandenabeele, P, Bromme, D, Puizdar, V, Fonovic, M, Trstenjak-Prebanda, M, Dolenc, I, Turk, V, Turk, B.
Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity
Cell Death Differ 10, 881-888, 2003. (Epub ---)

Saelens, X, Vandenabeele, P.
Type II autophagic cell death and death-associated protein kinases
Chemtracts, Biochem Mol Biol 16, 387-392, 2003. (Epub ---)

Vanden Berghe, T, Kalai, M, van Loo, G, Declercq, W, Vandenabeele, P.
Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis
J Biol Chem 278, 5622–5629, 2003. (Epub 2002 Nov 18)

van Gurp, M, Festjens, N, van Loo, G, Saelens, X, Vandenabeele, P.
Mitochondrial intermembrane proteins in cell death
Biochem Biophys Res Commun 304, 487-497, 2003. (Epub ---)

van Loo, G, Lippens, S, Hahne, M, Matthijssens, F, Declercq, W, Saelens, X, Vandenabeele, P.
A Bcl-2 transgene expressed in hepatocytes does not protect mice from fulminant liver destruction induced by Fas ligand
Cytokine 22, 62-70, 2003. (Epub ---)

Beyaert, R, van Loo, G, Heyninck, K, Vandenabeele, P.
Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas
Int Rev Cytol 214, 225-272, 2002. (Epub ---)

Kalai, M, van Loo, G, Vanden Berghe, T, Meeus, A, Burm, W, Saelens, X, Vandenabeele, P.
Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA
Cell Death Differ 9, 981-994, 2002. (Epub ---)

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